association	dataset	threshold value	standardized value
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2608
SW1271	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE130081,GSE130082_0_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ebolavirus(ZEBOV)_1day_Spleen_None_GSE57214	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.69544
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.116
ZBTB32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50521
SLC35B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34995
OB granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.01704
TRIM5	Pathway Commons Protein-Protein Interactions	1.0	null
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28393
HDAC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77886
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5560-01A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATP1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96586
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUR-01A-21R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76725
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.35794
Medial amygdalar nucleus, posterodorsal part, sublayer a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24036
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.978492
increased basophil cell number	MGI Mouse Phenotype Associations 2023	1.0	null
MTMR9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3
ZFP64	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50001
hsa-miR-4638-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
NMRK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62739
HSD11B1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00463
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04468
HOOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50203
ARL4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95341
COPG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92505
Brain Lower Grade Glioma_LGG_TCGA-QH-A6CY-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GUCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4847
TCF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48836
VLDLR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29826
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.9902
Longissimus lumborum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.644
ARVCF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2089
cysteine-type peptidase activity	GO Molecular Function Annotations 2025	1.0	null
KRT18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22966
GSE130081,GSE130082_5_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21663
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
EN	DepMap CRISPR Gene Dependency	1.0	3.61596
PARD6G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07619
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.014
E2F8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97546
IRF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31248
layer 1 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3762
UACC812	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.84657
NANS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84451
H3K9me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.4098
NFYB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary somatosensory area, mouth, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35408
REPIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09478
PHF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31205
Inferior salivatory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.47212
127399	DepMap CRISPR Gene Dependency	1.0	2.89423
NKX2-6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09811
U2OS	CCLE Cell Line Gene CNV Profiles	1.0	1.56987
Cerebellum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
mantle zone of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.12697
PAX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54122
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4352-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE200673,GSE200691_1_v_4_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.033
Agranular insular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14334
ASH1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98871
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.984476
ventrolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.86245
PMC7910580-41467_2021_21715_MOESM3_ESM.xlsx-DUBs_screen-Supplementary_Data_1_Results_of_DUB_shRNA_screen_ZUP1	Rummagene Transcription Factor Associations 2026	1.0	null
SLC46A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58285
HSD17B10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86083
superficial stratum of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39698
Sarcoma_SARC_TCGA-X6-A7W8-01A-21R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SURF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62805
EM2	DepMap CRISPR Gene Dependency	1.0	2.27553
HOP-62	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3937
BRD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81121
ZNF384_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZFTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7907
mantle zone of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20053
NCI-H3122	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.7119
GSE120413,GSE120447_0_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7134
P2RY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41545
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06316
SWI5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48808
mantle zone of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29802
r1 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39224
hsa-miR-4784	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
Plagl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.6747
MYC_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-MN-A4N5-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.309
SLC25A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76046
HCC89	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11985
TRIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01051
MZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21718
Crus I, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16484
HT1197	DepMap CRISPR Gene Dependency	1.0	3.31645
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB1-F2del_7Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.53785
THAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71039
Lung adenocarcinoma_LUAD_TCGA-78-7155-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAB11FIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.433
ALDH6A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68025
EEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67512
GTSE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.454
Lung adenocarcinoma_LUAD_TCGA-75-5147-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ASPC1	DepMap CRISPR Gene Dependency	1.0	4.35178
SEPTIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2557
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A708-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1166
VZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.913342
RNF24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60827
LPS6	DepMap CRISPR Gene Dependency	1.0	5.41895
GSE196671_5_v_8_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18121
intermediate stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01147
NDUFS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18255
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01068
BRISC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.577
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06404
IZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.902585
PWWP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60301
RAB12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38822
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SELENON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60743
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.999052
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48012
Agranular insular area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53944
Cerebellar ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.573
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
mantle zone of VPrP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13761
mRNA_SMAD4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PET100	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10244
BTAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39635
AP2M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0248
parasubicular cortex (parasubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.35465
MYBPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83288
PUM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73456
nucleus sagulum, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39765
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.954917
TRIM39	Pathway Commons Protein-Protein Interactions	1.0	null
LRRC26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03151
Lung adenocarcinoma_LUAD_TCGA-53-7624-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
globose nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.23744
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.66308
Perturb_5092_KO_Max_SRP078684	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.31913
TTYH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31623
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.80918
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q4-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNF2	Pathway Commons Protein-Protein Interactions	1.0	null
HEL9217	DepMap CRISPR Gene Dependency	1.0	2.20144
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.86507
SAMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48154
MAPK8IP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51938
GYG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51791
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73F-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0334
parasubthalamic nucleus (migrated)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05806
LDB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27646
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.933345
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.968943
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.85063
DIS3L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22303
PMC8528285-pbio.3001085.s010.xlsx-Fig_7A-MLX_TESTES_MLX	Rummagene Transcription Factor Associations 2026	1.0	null
STAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55882
CAL851	CCLE Cell Line Gene CNV Profiles	1.0	2.00839
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14504
cochlear nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.900985
SOCS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80192
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.985025
metabolic process	GO Biological Process Annotations 2015	1.0	null
mantle zone of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10357
H4C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30562
SUIT-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FBXO45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51507
Prostate adenocarcinoma_PRAD_TCGA-KK-A7B2-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100359_PCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.37048
PMC12081856-41420_2025_2522_MOESM6_ESM.xlsx-Sheet_1-Table_S4_Complete_Gene_List_of_the_MEblack_Gene_Module_and_the_DUB_Family_ZUP1	Rummagene Transcription Factor Associations 2026	1.0	null
FKBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55283
peripheral portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.45033
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.45272
RAX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12917
OGG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41114
PAX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24687
TRMT61A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79567
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5293
HDGFL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24286
THY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06086
DGKQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57589
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.125
increased circulating HDL cholesterol level	IMPC Knockout Mouse Phenotypes	1.0	null
ZBTB47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02154
intermediate stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31879
PMC7300082-41598_2020_66556_MOESM11_ESM.xlsx-Supplementary_Table_10-TGIF1_TGIF1	Rummagene Transcription Factor Associations 2026	1.0	null
LMSU	CCLE Cell Line Gene CNV Profiles	1.0	1.90595
YIPF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44068
CCDC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11966
Primary motor area, Layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17342
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.5075
TCF7L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58384
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2154
LU99	CCLE Cell Line Gene CNV Profiles	1.0	2.20946
HMX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30624
ventrolateral part of m2A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24227
P30-OHK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNU449	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71686
H3K9me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZNF674	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80907
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.937876
ICC2	DepMap CRISPR Gene Dependency	1.0	11.4751
GSE226316_11_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
lateral part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04632
orbital frontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.827289
ubiquitinyl hydrolase activity	GO Molecular Function Annotations 2015	1.0	null
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.144
Perturb_5059_KD_Usp7_SRP235595	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.40561
CD47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32753
peptidase activity, acting on l-amino acid peptides	GO Molecular Function Annotations 2015	1.0	null
CTCF_GM20000_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STK11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82039
Primary somatosensory area, unassigned, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13593
HCC1395	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35576
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5479
PMC12855127-Table1.xlsx-Sheet1-Table_S1_A_total_of_576_E3_genes_and_95_DUB_genes_were_identified_in_the_iUUCD_2_0_database_ZUP1	Rummagene Transcription Factor Associations 2026	1.0	null
PIP5K1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68956
APBB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75134
ABHD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92412
H3K9me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
protein deubiquitination	GO Biological Process Annotations 2025	1.0	null
ZMAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05073
protein K27-linked deubiquitination	GO Biological Process Annotations 2025	1.0	null
MED14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73641
PROP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44557
cysteine-type peptidase activity	GO Molecular Function Annotations 2023	1.0	null
Retrosplenial area, lateral agranular part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41058
outer SZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.858715
CHCHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97439
GSE125219,GSE125221_3_v_8_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
Esophageal epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.604
PTPRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8012
KCTD17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91449
TAGLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74889
liver	HPA Tissue Protein Expression Profiles	-1.0	-0.964232
KLHL36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94564
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.955371
PALD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92898
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.143
intermediate stratum of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96569
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A4BA-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEF2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3512
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.191
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9346
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.93829
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GLUD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10469
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26556
superficial stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1532
Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NN-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARHGAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.79696
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0102
LACTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99515
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.44951
Prostate adenocarcinoma_PRAD_TCGA-G9-6365-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD151	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07706
WDHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74242
ZC3HAV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98708
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2776
CALM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19596
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
dorsal subnucleus of MG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03128
GCM2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1994
SAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5956
GSE149075_3_v_11_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PCSK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37141
REL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46616
ZKSCAN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33004
SG in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13748
SARAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76214
layer IIIu of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.16486
496100389_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.12549
LTBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38235
PMC12719073-mmc1.pdf-24-DUB_ZUP1	Rummagene Transcription Factor Associations 2026	1.0	null
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.203
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5885-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
parvocellular part of r8LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68301
LLGL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36294
TRIM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03299
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WX-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CSDE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95695
IGR1	CCLE Cell Line Gene CNV Profiles	1.0	1.35754
GSE127790_13_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A498	CCLE Cell Line Gene CNV Profiles	1.0	1.85678
CTCF	ENCODE Transcription Factor Targets	1.0	null
IPO8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9802
MFAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41831
proteolysis	GO Biological Process Annotations 2015	1.0	null
RNF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37225
periventricular stratum of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81059
H3C8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6524
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9315
KIRREL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98426
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05666
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.40178
ZNF853	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47111
DPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98231
PMC9225015-elife-72879-supp6.tsv--DUB_ZUP1	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73899
vagina	HPA Tissue Protein Expression Profiles	1.0	1.70014
Brain Lower Grade Glioma_LGG_TCGA-HT-8011-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78639
ANTXR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21695
GSE216043_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
TNFAIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92997
VAMP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52857
NFYB	ENCODE Transcription Factor Targets	1.0	null
medial amygdala, anterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08452
PSMD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44938
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.975058
ACVR2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91231
UBXN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41911
CAPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04598
subbrachial nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93145
cellular protein modification process	GO Biological Process Annotations 2015	1.0	null
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47037
periventricular stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.02551
MARF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10855
r3 liminal central gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22721
TRIM45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33965
OXTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25502
GSE159937_1_v_0_tfcp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FU-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26238
Central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MCM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2945
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3041
STARD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59099
TIA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42744
mRNA_EOMES_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Primary somatosensory area, unassigned, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22181
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7297
fallopian tube	GTEx Tissue Gene Expression Profiles	1.0	1.55635
Lateral reticular nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48949
Acute Myeloid Leukemia_LAML_TCGA-AB-2872-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04999
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4813-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
496100349_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.36458
MLLT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68751
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.39267
protein K27-linked deubiquitination	GO Biological Process Annotations 2023	1.0	null
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28901
H3K9me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EDEM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36973
SPAST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85933
Gastrointestinal tract	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ADNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04737
HCC70	DepMap CRISPR Gene Dependency	1.0	5.43009
SUOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51534
HLA-A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22705
GSE179002_2_v_6_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PLAUR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60212
Sublaterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05313
ALX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97056
hsa-miR-4668-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
ERCC4-ERCC1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.771
RUSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62171
substantia nigra, pars compacta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.889594
MYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7557
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PLOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85513
Vagina	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BMPR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71505
CEBPB-21427703-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
EEF1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-7.82121
SUSD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95858
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70E-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.42494
layer 3 of VPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02718
FOXS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35934
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.1958
protein K33-linked deubiquitination	GO Biological Process Annotations 2023	1.0	null
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.0127
REEP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96021
olfactory bulb, principal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4508
MARK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19005
FOXI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34088
ANKRD39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58987
PRDX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4375
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6324-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A76B-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.7995
MRPS27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06858
hsa-miR-3678-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Acute Myeloid Leukemia_LAML_TCGA-AB-2941-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.27746
CX3CL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00015
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09292
retina	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.880172
microcellular tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.47386
layer 4 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17342
Main olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46243
hsa-miR-5095	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
PMC9574515-mmc2.xls-THP1_0_min_GM-CSF-Target_Gene_Symbol_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
PROCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85179
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.865176
UCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10632
NCIH650	CCLE Cell Line Gene CNV Profiles	1.0	1.47557
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02075
RGS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27163
NCIH747	CCLE Cell Line Gene CNV Profiles	1.0	1.46317
MIEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40394
Brain stem	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27447
H3K27me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.827672
Brain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TMEM208	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65989
WDR73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26411
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10265
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.71552
intermediate stratum of m2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.3123
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-885-ENSG00000189299_FOXR2	Rummagene Transcription Factor Associations 2026	1.0	null
Lymphoid tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
LU-134-A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PPP1R1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19082
DOLPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23042
STK25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87984
BTBD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80087
IGLON5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44853
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
hsa-miR-4510	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Lung adenocarcinoma_LUAD_TCGA-05-4402-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
protein K11-linked deubiquitination	GO Biological Process Annotations 2025	1.0	null
MYL12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64777
lateral part of r8B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.1253
Agranular insular area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48658
RPEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97241
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.324
NP5	DepMap CRISPR Gene Dependency	1.0	7.5917
parabigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.38637
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.859018
FASTKD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20835
ABCC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74625
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WQ-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Yy1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.7206
HUH7	CCLE Cell Line Gene CNV Profiles	1.0	1.47468
PMC9574515-mmc1.xls-THP1_0_min_GM-CSF-Target_Gene_Symbol_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
ZFP69B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34106
DNAJC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90933
stratum lacunosum-moleculare of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.60038
principal sensory nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17644
DGKE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3781
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0157
PCYT1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25427
OB inner plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.07683
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTF2H2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95795
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.60466
mantle zone of r7Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33107
PTPRZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58808
NDUFS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37688
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3342
LRRC58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94224
Colonic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.103
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM132A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03078
COMMD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57829
RCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44917
SW954	DepMap CRISPR Gene Dependency	1.0	2.75329
SNU46	DepMap CRISPR Gene Dependency	1.0	2.66465
STEAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3331
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17436
SUM102PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.37299
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.24039
UDP-N-acetylglucosamine transferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.925
FOXA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05467
MCM3AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32819
nucleus of the inferior collicular brachium, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.29292
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33263
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.835685
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.5344
superficial stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70682
CBLC	Pathway Commons Protein-Protein Interactions	1.0	null
ECI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27595
EVX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16297
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NV-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
increased circulating cholesterol level	MGI Mouse Phenotype Associations 2023	1.0	null
Paragigantocellular reticular nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.55459
r3 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45298
MLH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41677
ABHD17A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4919
Fundus of striatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07963
RFLNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8933
LIN28A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60968
r10 part of vagal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02395
ASB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63199
RCM1	CCLE Cell Line Gene CNV Profiles	1.0	1.4597
Ar	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.4893
OVCA 429	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.966817
ZNF91	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65212
GTPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79085
ERBIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67811
intermediate stratum of isLim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60879
ZNF66	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00305
RABGGTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65945
S1PR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66414
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.75916
GSE127790_6_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
C4orf3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61582
BHLHE40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28463
PITPNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79533
PI4KB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24686
Lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42556
Prostate adenocarcinoma_PRAD_TCGA-HC-7078-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
protein k29-linked deubiquitination	GO Biological Process Annotations 2015	1.0	null
YIPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6571
Crus 1, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01184
496100380_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.70932
IZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.936685
ZNF444	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16484
MZ in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.898757
parathyroid gland	HPA Tissue Protein Expression Profiles	-1.0	-1.93195
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.864936
HCC44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.07409
GSE83145_1_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ARHGAP35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17222
PDE7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91809
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Brain Lower Grade Glioma_LGG_TCGA-HW-8319-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HUH1	CCLE Cell Line Gene CNV Profiles	1.0	1.42376
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-436-FOXR2_FOXR2	Rummagene Transcription Factor Associations 2026	1.0	null
SMIM30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71257
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.005
PC3	DepMap CRISPR Gene Dependency	1.0	3.718
CERS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2097
laterodorsal part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01596
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6435
EB1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.92848
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5262-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15257
GSE130081,GSE130082_4_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Facial motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46706
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41663
H3K9me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
ARF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83908
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF773	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29087
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.27783
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.899889
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K36me3_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7058
protein modification by small protein removal	GO Biological Process Annotations 2015	1.0	null
PPM1F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76344
TP53_01_68	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.69074
Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.91965
VMRCLCP	CCLE Cell Line Gene CNV Profiles	1.0	2.09423
subbrachial nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61374
protein k33-linked deubiquitination	GO Biological Process Annotations 2015	1.0	null
LU-135	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HOXD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52224
Sarcoma_SARC_TCGA-DX-A7ER-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78O-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Accessory olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25776
E2F6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32315
NPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.31157
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.883838
esophagus	HPA Tissue Protein Expression Profiles	1.0	1.70014
Stat5a::Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.1319
Lung adenocarcinoma_LUAD_TCGA-55-A4DF-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PGAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57155
molecular_function	GO Molecular Function Annotations 2015	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-YY-A8LH-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.126
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.9619
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.76138
CCDC142	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54606
ADD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44579
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5183-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Six3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.1904
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.96791
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08941
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
ELK4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0913
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.74918
ENSG00000170846	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69918
corticoid layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12807
PMC8528285-pbio.3001085.s010.xlsx-Fig_S7A-GENE_LIST_UPLOADED_TO_ENRICHR_MLX_TESTES_855_GENES_MLX	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZKSCAN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.9381
PARP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94913
H3K9me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
LEMD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94175
periventricular stratum of r2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22653
RAB3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58543
SNUC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6409
EGR1	ENCODE Transcription Factor Targets	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-4756-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
mantle zone of m2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24164
small intestine	HPA Tissue Protein Expression Profiles	1.0	1.70014
Perturb_17309_KO_Ddx25_SRP247988	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
METTL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72314
TSPAN14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40616
Locus ceruleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11584
hsa-miR-1252	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2807
lateral terminal nucleus of the accessory optic tract, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.12015
ventrolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25931
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3416
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.8701
H2BC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77795
PROKR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11978
intermediate stratum of m2AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18044
CSNK2A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86025
IZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08196
LSM12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55621
SPRR2F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57296
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
protein K11-linked deubiquitination	GO Biological Process Annotations 2023	1.0	null
IRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82794
GSE203329_2_v_1_mettl5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXA1-25552417-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
primary auditory cortex (core)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3209
PTGES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99797
Cornified envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.743
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NN-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9me3_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
INAFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15089
PANC 05.04	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.864799
Central lateral nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07294
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.856089
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A4AV-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70C-01A-21R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STPG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29764
LINGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02378
liminal alar domain of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24036
appendix	HPA Tissue Protein Expression Profiles	-1.0	-0.964232
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
ZNF599	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81054
MLYCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70589
Nucleus of the brachium of the inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02871
NUDUL1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35512
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.99396
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47134
insular cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.019
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
RPUSD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34398
mantle zone of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01745
STXBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78572
Brain Lower Grade Glioma_LGG_TCGA-DU-7301-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.87301
CD55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31747
Nucleus sagulum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23351
DPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40446
r7 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.84082
intermediate stratum of r4Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41711
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.826441
Paragigantocellular reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.17516
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-UC-A7PF-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE118765_1_v_5_rreb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RBPMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8037
GSE127790_10_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RAB1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37325
anterior pretectal nucleus, ventral superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60667
mantle zone of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45216
peptidase activity	GO Molecular Function Annotations 2015	1.0	null
FTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53822
hsa-miR-3620	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Accessory olfactory bulb, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13593
YD38	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45096
periventricular stratum of r3Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22721
PIGQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81825
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
periventricular stratum of r10Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02626
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3876
CPCN	CCLE Cell Line Gene CNV Profiles	1.0	1.60969
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RN-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CSNK1G2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72317
GSE200673,GSE200691_2_v_4_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.9284
GSE198165,GSE198166_5_v_11_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RTL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49487
PANX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56343
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A819-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE226316_4_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AKAP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11739
nucleus of the inferior collicular brachium, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83388
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.39889
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.865884
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25S-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.38534
ANOS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0751
ADSS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74564
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.01339
Piriform area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1169
FARAGE	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A7CF-02A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.948247
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33309
superficial stratum of r3BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45036
layer 2 of LPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1275
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.711667
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5888-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5578490-pgen.1006879.s017.xlsx-Top_ETV1_downregulated_genes-Gene_Symbol_ETV1	Rummagene Transcription Factor Associations 2026	1.0	null
OS9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06578
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4718
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.185
18614019-TableS4c	GeneSigDB Published Gene Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7689-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13033
PXYLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07376
H3K9me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QY-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.75301
ZNF780A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01381
SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0393
protein K29-linked deubiquitination	GO Biological Process Annotations 2025	1.0	null
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.8537
r8 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58304
NCIH716	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76154
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CREB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94741
HES4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66291
SUMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46197
Perturb_5669_KD_Yy1_SRP281855	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	17.1965
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.056
AOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04487
Brain Lower Grade Glioma_LGG_TCGA-TM-A7CF-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BSG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45139
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
IM9	DepMap CRISPR Gene Dependency	1.0	3.21916
Immune system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NPTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43121
CSNK1G3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56305
mRNA_MEF2C_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE107505_3_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.79786
FGFR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03947
hsa-miR-4749-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AQ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXA1-26743006-CHIP-SEQ-LNCAP-ABL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.13477
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.26941
NCIH3122	DepMap CRISPR Gene Dependency	1.0	5.83295
GSE127790_9_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HES7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8452
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02075
CPXM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04797
hsa-miR-3065-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
CALM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28035
CROCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85634
CCNY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02165
TLK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54787
NAT8L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17838
GSE202603_1_v_2_bhlhe40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PRR15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24883
periventricular stratum of r1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24
CMTR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55441
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.913
CDS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64375
Male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
TUT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04762
cellular process	GO Biological Process Annotations 2015	1.0	null
hsa-miR-3622a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Site of DNA damage	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.799
HDAC6	ENCODE Transcription Factor Targets	1.0	null
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.30109
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.865
GTF2IRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32551
Prostate adenocarcinoma_PRAD_TCGA-EJ-7789-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SEC24C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15747
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.74805
GTEx Testis 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-3.91443
KLHL24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40915
SPAG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60593
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6845
external part of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70334
YWHAE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79824
EPHA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65462
MZ in dorsomedial parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0284
MZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.837736
MAP1S	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64147
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.823959
Acute Myeloid Leukemia_LAML_TCGA-AB-2995-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7080-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Main olfactory bulb, inner plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.42029
CCN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04704
fastigial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.954253
CAL62	CCLE Cell Line Gene CNV Profiles	-1.0	-2.3514
MED23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42893
NCI-H1417	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RGL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10075
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.846914
GNPDA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66227
TC-YIK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1662
Bed nuclei of the stria terminalis, anterior division, fusiform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63644
TINF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09194
COPRS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26226
mantle zone of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0451
CELF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29496
GSE226316_6_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SG in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19064
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.5523
SPACA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04052
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1307
Lung adenocarcinoma_LUAD_TCGA-44-2665-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03756
CBLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18505
hsa-miR-4456	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
OTUD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3022
GSE238018_3_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC39A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07305
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.55878
GSE173873_8_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
QTRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78915
r8 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96305
VCaP cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.87
PMC5727433-41467_2017_2029_MOESM3_ESM.xls-Sheet1-Supplementary_Data_1_DUB_shRNA_list_used_in_this_study_ZUP1	Rummagene Transcription Factor Associations 2026	1.0	null
KM-H2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.114
r7 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86564
NPAS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45693
VZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.961311
TREX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90668
PPM1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21869
FADU	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
ESR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.306
SMG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3805
IZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.986402
superficial stratum of r7Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69704
Primary motor area, Layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09538
hsa-miR-3919	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
C1orf210	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45569
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2439
NCI-H2009	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.7119
SLC35E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3758
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Skeletal Muscle Female	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.51799
Agranular insular area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07963
liminal reticular formation of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.73686
oculomotor nuclear complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.62499
H3K9me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
increased eosinophil cell number	MGI Mouse Phenotype Associations 2023	1.0	null
ITGA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31226
ASXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13293
Brain Lower Grade Glioma_LGG_TCGA-RY-A843-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Smooth endoplasmic reticulum membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.793
Pontine reticular nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14967
Lung adenocarcinoma_LUAD_TCGA-49-4490-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBE2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45627
Brain Lower Grade Glioma_LGG_TCGA-FG-A60J-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE235596_0_v_1_pikfyve_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.900266
isthmic vestibulocerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21959
hsa-miR-4435	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
stratum lacunosum-moleculare of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11459
GOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18984
SCABER	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61651
Cortical amygdalar area, anterior part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23351
PRRC2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60985
ZSWIM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05762
VZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.57669
TK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ACSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84781
SELENOO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48604
PCIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69154
hsa-miR-1976	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
DBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3495
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15326
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_T_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r9 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01147
RBBP5	ENCODE Transcription Factor Targets	1.0	null
ACHE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76667
CAKI2	DepMap CRISPR Gene Dependency	1.0	2.11418
YTHDF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69484
UPCISCC116	DepMap CRISPR Gene Dependency	1.0	4.94938
ADPRH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63399
Autosomal dominant cerebellar ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.773
increased circulating cholesterol level	IMPC Knockout Mouse Phenotypes	1.0	null
hippocampus (hippocampal formation)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04751
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15171
PROX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6782
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.9543
PBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32791
cuneiform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1793
NCI-H2347	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KMS20	DepMap CRISPR Gene Dependency	1.0	2.29576
PRKD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3264
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.873818
superficial stratum of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95227
Ovarian Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
MAP6D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72398
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.22837
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.953979
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
AFF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34457
Lung squamous cell carcinoma_LUSC_TCGA-63-7020-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE127790_11_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary motor cortex (area M1, area 4)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-3.19599
Embryonic cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.524
NME4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75133
Spinal nucleus of the trigeminal, oral part, rostral dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02626
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35565
PMC6930440-jcav11p0520s3.xlsx-MI_vs_FG-Unnamed_0_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_5093_KO_Mga_SRP078684	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.69791
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.996044
Nucleus of the lateral olfactory tract, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03075
Intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6094
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.923993
MYOZ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3112
CHD2	ENCODE Transcription Factor Targets	1.0	null
496100549_FWM_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.08449
AP3D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65996
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.857297
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.97905
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3679
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51R-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adrenal cortex cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.554
Primary somatosensory area, unassigned, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22552
GBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53496
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-4710	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.3176
layer I of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.870503
H3K9me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bronchus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SW 780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.865475
FBXO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4544
RERFLCAD2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6032
Accessory olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08399
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7449
ZSCAN20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65085
GSE199255,GSE199356_6_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8345-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C9orf40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15602
superficial stratum of InsCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01953
ATG14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98114
FZD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86187
PRKAG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18095
GSE102505_1_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC1162	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1307
MZ in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.847799
496100355_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.05488
r7 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03713
NCIH2882	DepMap CRISPR Gene Dependency	1.0	10.6677
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
ERF::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2363
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.935524
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.134
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9627
EID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95716
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.0859
subparafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.894133
COIL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22744
ROR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59397
SIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40425
Machado-Joseph disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.0
PPCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89705
ZFP14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.2142
OSBPL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5914
TUBB2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36538
MALSU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77489
GSE201877_1_v_0_yap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25216
Lung adenocarcinoma_LUAD_TCGA-55-7995-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.64912
TE5	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59447
VANGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48183
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1307
POLR2A	ENCODE Transcription Factor Targets	1.0	null
substantia nigra, reticular part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10697
PODXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22438
LRRC34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56517
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HT1376	CCLE Cell Line Gene CNV Profiles	1.0	1.75331
184A1N4	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.04589
hsa-miR-3667-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.147
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.62102
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A1-11A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LZTS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3503
C5orf24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4347
NACA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78296
Agranular insular area, ventral part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28462
KP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26338
RHBDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50831
PARP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56103
Junctional epidermolysis bullosa non-Herlitz type	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.196
TCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1464
VMAC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55722
PRMT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94588
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16193
FASTKD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60978
DUS1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52379
Superior olivary complex, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25689
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23751
Lung adenocarcinoma_LUAD_TCGA-MN-A4N4-01A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Agranular insular area, ventral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79725
TMEM106C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00661
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27335
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.137
SG in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28067
rostral ventrolateral reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.79786
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70N-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MZ in retrosplenial cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02658
H3K9me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE233679_14_v_4_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
r7 portion of ambiguous motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69816
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.9888
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6942-01A-21R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EDEM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56139
A1CF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82003
PPRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65122
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MY-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VCP-NSFL1C complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.107
RELCH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2816
ABT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54274
UACC893	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.30402
GSE179002_3_v_8_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE241701_4_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K36me3_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
INPP5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31147
r8 part of lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.87318
Superior vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39139
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TY-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10036
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6909-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.96268
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ES-WA7 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.13662
ZNF692	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96087
TTLL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10914
Lung adenocarcinoma_LUAD_TCGA-67-3771-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATP6V0E2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10357
Small intestine mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.512
TAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48784
PTPRS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14639
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05735
H3K23me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_GM13976_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cul7-RING ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.702
H3K9me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16936
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
COLO 800	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.70317
RBCK1	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-FC-A8O0-01A-41R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD164L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04168
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RM-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ITCH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31202
laterostriatal stripe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03903
H3K9me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A6YR-01A-33R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90128
dorsal paracommissural tectal nucleus, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03345
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.64207
VZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.45273
PMC9574515-mmc1.xls-THP1_60_min_GM-CSF-Target_Gene_Symbol_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
Ovarian tumour, otubain	InterPro Predicted Protein Domain Annotations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-6513-01A-21R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r2 liminal central gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22794
Hereditary ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.561
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LA-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cysteine-type deubiquitinase activity	GO Molecular Function Annotations 2025	1.0	null
CTNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72746
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14561
Pancreatic adenocarcinoma_PAAD_TCGA-LB-A7SX-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1423
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A4XJ-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100434_HIP_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.04398
PK-59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02075
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7801
496100631_PCx_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10362
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10987
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.16011
microcephaly, seizures, and developmental delay	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.355
FKBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61221
NMU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32621
FAM170A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97593
A3KAW	DepMap CRISPR Gene Dependency	1.0	6.41313
FIZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87066
GAPDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39396
CERS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93716
TRERF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.673
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.58521
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11836
ANGEL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56338
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8182
NT5C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09917
UHRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28941
deubiquitinase activity	GO Molecular Function Annotations 2025	1.0	null
CLPP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58101
PNMA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37753
RAB8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82526
superficial stratum of CoPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.1224
paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14719
SARS-CoV MA15_Day7-PFU-10^4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.88055
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11836
NCIH1573	DepMap CRISPR Gene Dependency	1.0	2.46469
SHMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.235
MYC	ENCODE Transcription Factor Targets	1.0	null
ABHD16B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.69046
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2658
GNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99301
NCIH1355	CCLE Cell Line Gene CNV Profiles	-1.0	-1.92591
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.57105
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_7E-MLX_TESTES_MLX	Rummagene Transcription Factor Associations 2026	1.0	null
SPRED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26473
CIITA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85308
r1 part of the 'mesencephalic' trigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41797
GSE189772,GSE189773_3_v_2_fbxo11_human	RummaGEO Gene Perturbation Signatures	1.0	null
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.00453
IDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55992
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RB-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54682
mRNA_DNMT3B_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
FOXO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46169
outer SZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.90773
CRAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23729
AR_01_278	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59355
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10R-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.70111
ISOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94197
Esophagus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
FAM181B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24489
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70K-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.31512
SP in entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.45525
TBX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68199
Bronchoalveolar system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
biological_process	GO Biological Process Annotations 2015	1.0	null
Respiratory system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
cysteine-type deubiquitinase activity	GO Molecular Function Annotations 2023	1.0	null
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.319
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.113
HCC1359	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.865475
RRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.64818
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08028
TRA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77489
CRTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60389
SCF-Skp2 ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.638
superficial stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26716
superficial stratum of Ist	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16014
THAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33347
amygdaloid complex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.49843
EGFR_druginhibition_82_GSE27638	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.32648
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2955
PMC8567280-EMBR-22-e53014-s008.xlsx-PC3_TIP5_bound_promoter-Unnamed_4_BAZ2A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE195559_0_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
A-Vietnam-1203_CIP048_RG3-2004(H5N1)_7Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.14034
para-abducens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05869
LUBAC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.58
gracile nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05607
ZNF669	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50924
H3-3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95405
DHRS7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28741
UGT3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4249
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09976
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lymph node	HPA Tissue Protein Expression Profiles	-1.0	-0.964232
COA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55386
PMC10335698-pone.0285806.s007.xlsx-DMKN-shRNA_KD_Vs_ShSrc-Unnamed_9_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE127790_5_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5817105-thnov08p0972s2.xls-SIX3_MTA3-GeneName_SIX3	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7745-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ALKBH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09161
FARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87493
lateral tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08557
GSE127790_13_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bed nuclei of the stria terminalis, posterior division, strial extension	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39224
Presubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25473
HAUS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26451
NUP88	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16939
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.98452
UBC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31806
GNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51573
SLC17A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62008
HNF4G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43707
GSE168797_1_v_3_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Gustatory areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05982
superficial stratum of LPrP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12309
HCC70	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.574613
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WO-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17526
Prostate adenocarcinoma_PRAD_TCGA-CH-5790-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0512
FBLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62591
PSS008	DepMap CRISPR Gene Dependency	1.0	3.03746
H3K9me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE48812_0_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DTX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6097
hsa-miR-4532	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
IZ in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.854708
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02075
Lung adenocarcinoma_LUAD_TCGA-95-8494-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BAK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27732
IKBKG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70684
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.9218
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-0.894895
FEM1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21318
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.923993
hsa-miR-1260	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
BRSK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35871
COL6A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87102
Superior olivary complex, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02277
ZSCAN32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8728
HCC2157	CCLE Cell Line Gene CNV Profiles	1.0	1.5046
DIAPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22831
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GMCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18852
GSE199255,GSE199356_6_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTSZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68006
Integument	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SQ1	CCLE Cell Line Gene CNV Profiles	1.0	1.37127
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.974243
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
dorsal periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00033
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.893105
NEK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69767
hsa-miR-4533	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9274
LMO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7774
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.64404
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE199255,GSE199356_3_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MDFIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45583
hsa-miR-4419a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
oculomotor nuclear complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05496
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RI-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17436
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WV-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IGFBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0311
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Small intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GRHPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64351
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.083
NR5A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67849
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01094
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.9326
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.80918
KYSE520	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4939
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RV-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDKN1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73634
Hematopoietic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ATP13A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36777
SSBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71114
Perturb_4559_KD_Rnf2_SRP126769	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.29423
UMUC3	CCLE Cell Line Gene CNV Profiles	1.0	1.34129
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26142
MZ in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15897
ZNF140	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.5033
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	69.4034
RTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81862
HCC1428	CCLE Cell Line Gene CNV Profiles	-1.0	-1.8092
COPS7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49322
Prelimbic area, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15302
DHRS4L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3019
ZNF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16433
superficial stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60879
ETFBKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87905
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A726-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15675
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HU-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.297
ZNF740	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97888
periventricular stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57119
GINM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.453
r3 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0408
Retrosplenial area, lateral agranular part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07375
KYSE-220	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Duodenum Mucosa	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.950394
PDX1	JASPAR Predicted Transcription Factor Targets	1.0	null
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5349
RHOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98692
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.995742
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.60013
ACAA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21129
GABRD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48147
ES-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49157
Lateral reticular nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41797
lateral part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1023
C19orf12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77718
DNASE1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33262
USP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89891
MYB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42898
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31218
ZNF584	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42517
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.842669
Medial amygdalar nucleus, anterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04218
SNU-1040	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.7119
Agranular insular area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23477
NCI-H650	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.948144
UMUC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43485
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A1-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior group of nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.87095
Main olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75157
intermediate part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08621
SUP-HD1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SKPNDW	DepMap CRISPR Gene Dependency	1.0	2.0025
SNU-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.937876
PDE6D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85547
GSE254848_9_v_8_ptges_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
body of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10521
CLDN34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16156
Gustatory areas, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41874
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1765
PPM1M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53034
CW9019	DepMap CRISPR Gene Dependency	1.0	2.11079
BTG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54781
NOL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54545
Skin	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21273
NCI-H647	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Meiotic prophase fetal germ cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
496100559_FWM_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.25256
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.969772
hippocampus	HPA Tissue Protein Expression Profiles	-1.0	-0.964232
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.847457
MYOCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3963
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE145249_0_v_3_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
MCRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99814
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.91351
subgranular zone of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.842496
CGTHW1	CCLE Cell Line Gene CNV Profiles	1.0	2.63432
VIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.898812
ZNF333	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19761
hsa-miR-3135b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.9414
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0715
spleen	HPA Tissue Protein Expression Profiles	-1.0	-1.93195
DHX40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22128
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05139
LIN28B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22623
intermediate stratum of m1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10802
MZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07067
EHMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92291
USP34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90361
ZNF124	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75582
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2273
HCFC1R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14245
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.058
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7529
RPSA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76554
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IR-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lm9	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.823
WASF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57667
REC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44758
superficial stratum of VPrP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44052
NUDT16L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24594
RNF139	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55035
GSE226316_1_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SFRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60063
PHF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96225
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IY-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DNAJB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60007
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_7day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.77131
PRRX2	JASPAR Predicted Transcription Factor Targets	1.0	null
PRDM16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18467
Bed nucleus of the accessory olfactory tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51663
corticoid layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01643
Inflorescence stalk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.046
SIX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35075
inferior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05124
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34762
Prostate adenocarcinoma_PRAD_TCGA-HC-A76W-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF878	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11207
SENP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76378
liminal part of the r7 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33028
protein deubiquitination	GO Biological Process Annotations 2023	1.0	null
SLU7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10788
CRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12061
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6906-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3861
r3 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34918
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90987
ZBTB11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9111
mantle zone of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.27106
Tonsil	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.147
PAK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00565
C20orf96	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51809
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ZNF775	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02179
valproic acid_mus musculus_gpl6246_gse23957	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
143B	CCLE Cell Line Gene CNV Profiles	1.0	1.64841
NCIH1703	CCLE Cell Line Gene CNV Profiles	1.0	1.38599
ZNF384	ENCODE Transcription Factor Targets	1.0	null
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7953
GSE168697_0_v_1_wdr6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8329168-41418_2021_763_MOESM8_ESM.docx-0-DUB_ZUP1	Rummagene Transcription Factor Associations 2026	1.0	null
PERP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23623
H3K9me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CCNC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63023
BMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70986
bronchus	HPA Tissue Protein Expression Profiles	1.0	1.70014
ovary	HPA Tissue Protein Expression Profiles	-1.0	-0.964232
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8871
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2910-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLCB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67041
DNM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95115
Parabrachial nucleus, medial division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09067
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7XO-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Piriform area, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17988
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05232
CTSF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4286
superficial stratum of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45654
A4 noradrenergic cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54474
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.8215
MRPL19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11983
Adrenocortical carcinoma_ACC_TCGA-OR-A5J9-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10806
THOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11415
496100381_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.03433
IRF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40249
H3K9me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FBXW5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.152
ATF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45564
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.045
NFYB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.78128
hsa-miR-92a-3p	MiRTarBase microRNA Targets	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE241701_1_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06607
MAX	ENCODE Transcription Factor Targets	1.0	null
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.858509
ZNF626	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07412
PMC7300082-41598_2020_66556_MOESM11_ESM.xlsx-Supplementary_Table_10-ZBTB10_ZBTB10	Rummagene Transcription Factor Associations 2026	1.0	null
ENAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51182
Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4U1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hyperactivity	IMPC Knockout Mouse Phenotypes	1.0	null
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.01
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A7IN-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HASPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68982
hypothalamic amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00787
layer 1 of LPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51934
amygdaloid complex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17046
PTPN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74973
Prostate adenocarcinoma_PRAD_TCGA-CH-5753-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70P-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GLO1_OE_GDS4991_546_mouse_anxiety disorders	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10189
GSE199255,GSE199356_6_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4476	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
protein k11-linked deubiquitination	GO Biological Process Annotations 2015	1.0	null
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.16529
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.13981
Perturb_4539_KD_A2l_SRP126769	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.32287
NAP1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04074
EVX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94143
Alimentary canal	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
VZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.829505
Prostate disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.01
CCDC174	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35117
ZNF430	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6539
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	107.096
cuneate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01056
MRPL41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65165
MATCAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5208
layer 2 of VPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38831
KANK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07627
PHF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83291
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7593-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LOU-NH91	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02896
MAN2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45807
NCIH727	CCLE Cell Line Gene CNV Profiles	-1.0	-2.00394
BFTC905	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44896
posteroventral (inferior) parietal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02007
MZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.827607
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC16A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15572
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.5604
Nucleus y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0445
NCOA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4769
PEPD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86401
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.36122
LLPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64776
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.937985
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM167A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56988
cuneus, right, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.884714
ACTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63136
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35655
Lung adenocarcinoma_LUAD_TCGA-67-3770-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.12294
SBC5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39593
Lung adenocarcinoma_LUAD_TCGA-55-8096-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAB14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90802
MRPS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86232
ZNF644	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46021
tail of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.964314
PHF5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60161
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MIER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92521
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.923993
cls1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.601
INO80E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97589
Primary somatosensory area, mouth, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47351
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11836
SW1573	DepMap CRISPR Gene Dependency	1.0	2.19983
IDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88101
posteroventral (inferior) parietal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23751
HNF4A	JASPAR Predicted Transcription Factor Targets	1.0	null
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.980369
inner SZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01044
TWF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00102
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A51X-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0373
STAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16191
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE125219,GSE125221_5_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
layer 1 of VPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78351
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.58644
TCP10L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26109
SFR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78699
TMCO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18341
Prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.013
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.75301
inner SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11068
Liver hepatocellular carcinoma_LIHC_TCGA-GJ-A6C0-01A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-4591-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of r1BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39057
HCC95	CCLE Cell Line Gene CNV Profiles	1.0	1.57913
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of r3Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04814
496100374_HIP_possible Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.78464
Primary visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0359
SW1271	CCLE Cell Line Gene CNV Profiles	1.0	1.78237
anteroventral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03533
XPO7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61098
ZNF384_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	46.1005
parasolitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.872767
amygdaloid complex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.4062
lateral ventricle	HPA Tissue Protein Expression Profiles	-1.0	-1.93195
496100357_TCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.64207
SLC6A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06378
TCTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87351
H3K36me3_CH12.LX_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ANG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04961
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DCUN1D5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82637
GSE195786_0_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7611
RIPPLY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06532
mantle zone of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08748
TENM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21929
r5 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41118
ZNF85	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19892
medial amygdala, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37487
GSE130081,GSE130082_0_v_10_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF596	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36412
Viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
EZH2	ENCODE Transcription Factor Targets	1.0	null
PACSIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76371
ADAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93869
ENGASE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46454
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IK-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40322
ubiquitin-like protein-specific protease activity	GO Molecular Function Annotations 2015	1.0	null
RBM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84485
IPPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22585
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4034
Lung adenocarcinoma_LUAD_TCGA-64-1679-01A-21R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4258	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
HDAC6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EXO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.79295
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5677
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.969042
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39Z-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.939147
OVCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7464
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.907261
primary auditory cortex (core)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32093
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5545
superficial stratum of AHy	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00787
ZNF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89731
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A4BK-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-8265-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
macromolecule modification	GO Biological Process Annotations 2015	1.0	null
Cortical amygdalar area, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06299
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.125
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2222
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.60645
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.893045
KHSRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90412
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.62283
PTPN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07299
VZ in midcingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23951
Sarcoma_SARC_TCGA-IF-A4AJ-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4651
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4691-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.863948
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
m1Lim part of the midbrain reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10912
TOLLIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19026
CUL4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72991
496100371_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.04815
FBXO28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2558
MAMSTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90632
GPRIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70503
trochlear nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.20081
HOXD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39323
GRIN2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18321
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.974243
HERPUD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60822
SULT1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11071
protein k27-linked deubiquitination	GO Biological Process Annotations 2015	1.0	null
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
INAFM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7735
SIN3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59345
Midbrain trigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19501
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.923993
MDAMB361	DepMap CRISPR Gene Dependency	1.0	2.97939
TOX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2358
ZR75B	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.549592
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18745
hsa-miR-607	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
YEATS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78897
ventromedial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2249
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAB24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50917
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.319
PLS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35146
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.908101
CEP85	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35077
CA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32543
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17436
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1035
Agranular insular area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2182
Cerebellar disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.552
CHRNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20512
USP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21003
LDB1-21186366-BM-HSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hydrolase activity	GO Molecular Function Annotations 2015	1.0	null
Rosette leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.611
ZC3H14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35068
SARS-BatSRBD_Day2_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.29096
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.5458
protein deubiquitination	GO Biological Process Annotations 2015	1.0	null
Main olfactory bulb, granule layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.96564
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02821
Parasubthalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65958
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF765	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98925
496100365_HIP_probable Alzheimer's disease_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.75666
r8 part of linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51075
NAA60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49021
TIE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33269
Prelimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44522
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20653
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7PW-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CLDN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27692
Posterolateral visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51055
EGR1	ChEA Transcription Factor Targets	1.0	null
USP22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64339
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.21239
ventral part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29951
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06471
KDM1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37442
r9 part of the lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36202
intermediate stratum of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24509
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10T-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MA-AA41-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARHGEF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05506
CIART	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7545
TMX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70805
TCF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19773
hsa-miR-4739	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Piriform area, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47625
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IG-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NABP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51428
MZ in posteroventral (inferior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.53843
WSB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42476
liminal part of the r6 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19783
GSE120413,GSE120447_4_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JHOS4	CCLE Cell Line Gene CNV Profiles	1.0	2.36415
DPP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69331
LRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41948
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.44912
r2 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44611
MZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.62813
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A262-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ANKRD13D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33042
r6 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2436
GSE131649_4_v_11_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.935524
CHID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55783
H3K9me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
PPARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.7857
Basomedial amygdalar nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37089
Brain Lower Grade Glioma_LGG_TCGA-HT-7884-01B-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE112860_3_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PRKD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24307
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SR-01B-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNFT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1135
UBR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09696
GPATCH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23139
Metencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
B4GALT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12086
Gustatory areas, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09647
TC138	DepMap CRISPR Gene Dependency	1.0	2.88568
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SNRPE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68044
CSRNP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34949
ZNF814	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30862
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.90375
YIPF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82207
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7696
PMC2809080-1471-2164-10-637.nxml--Missing_DUB_Genes_Protein_in_Zebrafish_ZUP1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE120413,GSE120447_3_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.927822
PIGS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71601
H3K9me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF227	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20543
retrotrapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0494
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23062
TSPYL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57952
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.845725
NCIH2009	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52516
RCCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12788
Female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.014
r5 part of A5 noradrenergic cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78809
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
CORT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08633
intermediate stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58207
GSE199255,GSE199356_4_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CELF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35214
CLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15946
principal sensory nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.39775
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5201-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRKCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5802
SCYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03484
GTF2A1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25113
ZNF559	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51874
FU-OV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Nucleus ambiguus, ventral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.9545
NR4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98694
PCDHB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92823
PMC10247733-41408_2023_863_MOESM4_ESM.pdf-591-ZNF774_ZNF774	Rummagene Transcription Factor Associations 2026	1.0	null
CSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75291
CA4 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.839077
mRNA_ASCL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.3359
KE39	CCLE Cell Line Gene CNV Profiles	-1.0	-2.20312
496100611_FWM_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.37304
MDAMB361	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63507
ubiquitin-specific protease activity	GO Molecular Function Annotations 2015	1.0	null
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Anchoring collagen complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.611
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A3JL-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-5668-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ENKD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10065
nucleus of the stria terminalis, medial division, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04526
HSDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56883
SREBF2	JASPAR Predicted Transcription Factor Targets	1.0	null
dentate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.982521
RAB23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30757
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.92994
UBC13-UEV1A complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.592
cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
ANXA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66846
Posterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09323
rostral putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.979207
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MF-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE146074_6_v_3_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5817
N4BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34813
STN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66008
EW-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.38337
AU565	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.884258
WWC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76183
RNH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77208
PIGV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51906
r9 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06429
increased basophil cell number	IMPC Knockout Mouse Phenotypes	1.0	null
MKI67	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72482
TCEAL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00343
Kidney Chromophobe_KICH_TCGA-KN-8426-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QG-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IMMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52515
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.866849
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
496100553_TCx_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.37938
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.3364
CORO1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75024
dorsolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05429
external segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.876594
TNPO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86957
SPTY2D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78526
GSE126621,GSE126920_1_v_0_dppa4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
outer CP in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.904224
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4670-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
intermediate stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86564
OCIMY7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34654
DISP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28511
intermediate stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.12534
Gustatory areas, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4099
NR4A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57559
OB outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32467
lateral part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.27106
TPRX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42388
superficial stratum of r5Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17982
GSE140092_2_v_1_socs3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IK-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.84997
Y-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.556
MT-ATP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8797
r4 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41625
mRNA_MSC_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
IV, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.47335
Main olfactory bulb, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44806
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10994
PMC9574515-mmc2.xls-THP1_60_min_GM-CSF-Target_Gene_Symbol_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5353
primary motor cortex (area M1, area 4)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3766
GSE173873_2_v_13_stra8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAFA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7731
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.98
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03906
HCC1569	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PLEKHO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64746
KYSE-30 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.971
molecular layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10994
TRAF3IP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57659
REM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14913
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.4231
CAL33	CCLE Cell Line Gene CNV Profiles	1.0	1.6884
ULK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75557
Hindbrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TRIM46	Pathway Commons Protein-Protein Interactions	1.0	null
outer SZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.995773
ERI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60162
KDM5A	ENCODE Transcription Factor Targets	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.4794
PMC5817105-thnov08p0972s2.xls-SIX3-GeneName_SIX3	Rummagene Transcription Factor Associations 2026	1.0	null
protein modification by small protein conjugation or removal	GO Biological Process Annotations 2015	1.0	null
YWHAZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4804
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.9165
PRKX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28497
SULF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89262
UNC50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39924
GPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49058
increased circulating HDL cholesterol level	MGI Mouse Phenotype Associations 2023	1.0	null
PMC8526018-KAUP_A_1856493_SM1378.xlsx-Table_S5-_DUB_genes-Table_S5_Compared_deubiquitinating_enzyme_genes_ZUP1	Rummagene Transcription Factor Associations 2026	1.0	null
GABRQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99516
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6606
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7591-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Trunk	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Brain Lower Grade Glioma_LGG_TCGA-P5-A72U-01A-31R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7QX-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_RHOX6_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
NKX2-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12046
VZ in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.886506
Pancreatic adenocarcinoma_PAAD_TCGA-S4-A8RO-01A-12R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4224-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.123
Excretory gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15546
WDR5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63597
layer 2 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34086
DENND6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52152
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.978261
DEXI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21949
NCIH1930	CCLE Cell Line Gene CNV Profiles	-1.0	-2.09288
Lung adenocarcinoma_LUAD_TCGA-50-6590-01A-12R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE179002_3_v_7_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
KDM5B	ENCODE Transcription Factor Targets	1.0	null
NDUFA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89741
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Adrenocortical carcinoma_ACC_TCGA-PK-A5H8-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Thorax	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Primary somatosensory area, unassigned, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.00793
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.877489
Head	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
OB mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35343
TFAP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55016
PRR22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8394
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.52353
SUPT3H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92286
protein K33-linked deubiquitination	GO Biological Process Annotations 2025	1.0	null
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.94303
ZNF726	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00365
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81P-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WIZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75718
hsa-miR-3150b-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
TRIM59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73951
HNRNPUL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00588
anaphase-promoting complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.182
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
small intestine	GTEx Tissue Gene Expression Profiles	-1.0	-1.38028
Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KT-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAB6D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27261
LYSMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07034
cysteine-type peptidase activity	GO Molecular Function Annotations 2015	1.0	null
Anterior amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31166
Anterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23103
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.823959
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.87009
NCIH1838	CCLE Cell Line Gene CNV Profiles	1.0	2.93448
ENHO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81647
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.865884
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
Acute promyelocytic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.736
PPP2R5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13519
Perturb_12599_KD_Gatad2b_SRP366371	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.46052
H3K9me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SEPTIN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68569
FOXD4L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47183
TMEM256	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62057
HDAC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81461
deubiquitinase activity	GO Molecular Function Annotations 2023	1.0	null
hsa-miR-4763-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
CCDC88C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81773
cellular macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8ID-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FUT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74353
dorsolateral preisthmic part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81059
LRRFIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61744
PPP2R3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93935
KYSE450	CCLE Cell Line Gene CNV Profiles	1.0	1.81639
ZNF781	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87941
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.75752
HPDL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57797
lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.958015
NCIH520	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5396
Nucleus of the lateral olfactory tract, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56203
SNU1033	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36447
HT55	COSMIC Cell Line Gene Mutation Profiles	1.0	null
paraterete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14025
ZNF383	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74839
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE195559_6_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PEMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72622
mantle zone of AHy	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00787
locus coeruleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23861
ANKS1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64123
Myc-CaP cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.336
HDAC2	ENCODE Transcription Factor Targets	1.0	null
SFXN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97555
496100369_PCx_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.42623
AFMID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33076
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TIGD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01599
SLC35B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3541
496100392_HIP_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.11662
MPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9112
PIGT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25234
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5058
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22935
E2F6	ENCODE Transcription Factor Targets	1.0	null
protein modification process	GO Biological Process Annotations 2015	1.0	null
PDXP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2125
Crus 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03282
ARID3A	JASPAR Predicted Transcription Factor Targets	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1M6-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine luminal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.687
salivary gland	GTEx Tissue Gene Expression Profiles	-1.0	-1.38028
Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.5525
TRIM65	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45426
PAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60924
CRYGD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59063
WDR83	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87241
Agranular insular area, ventral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22367
STEAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10875
CXCL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90531
KCTD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70334
hsa-miR-1280	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
NT5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22265
MZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.897341
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4602
hsa-miR-4756-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
VDR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73972
hsa-miR-720	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
intermediate stratum of r5Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40951
PHC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82962
SLC35C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00706
SSH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31017
intermediate stratum of r7Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.84082
LTA4H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0555
RS4-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Breast	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
C1orf226	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44164
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5319
ERBB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5018
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZBTB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27207
RIMKLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73607
COLO-320-HSR	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-1260b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
PLBD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6722
Sarcoma_SARC_TCGA-DX-A8BZ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCMH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01781
cervix uteri	GTEx Tissue Gene Expression Profiles	1.0	1.23077
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.65014
MZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.7007
ZNF581	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80177
protein metabolic process	GO Biological Process Annotations 2015	1.0	null
ventropallial prepiriform area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13706
D423MG	DepMap CRISPR Gene Dependency	1.0	16.3119
FLYWCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67985
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TESK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97193
Perturb_16084_KO_Nfya_SRP270915	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.29208
DDIT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75242
FAM216A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95011
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5264-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FARP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43595
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-4794	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
intermediate stratum of r2BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43756
MGAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95382
NDUFB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26284
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-1321	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7924-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZRANB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28949
Barrington's nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3783
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06753
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.23019
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0796
superficial stratum of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03345
NCIH1568	CCLE Cell Line Gene CNV Profiles	-1.0	-1.86706
Lung	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
medial amygdala, posterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04113
PMM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31839
TMEM37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34728
layer 3 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28524
Parabrachial nucleus, medial division, medial medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08877
CDC25B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66565
PGBD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.36879
GSE117212,GSE117214_0_v_1_zbtb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3995
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04141
OAZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98409
DNMT3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80589
Colon cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
SH10TC	DepMap CRISPR Gene Dependency	1.0	2.18133
protein K29-linked deubiquitination	GO Biological Process Annotations 2023	1.0	null
increased eosinophil cell number	IMPC Knockout Mouse Phenotypes	1.0	null
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.967045
ZNF257	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.6396
r10 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44867
SMC1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01353
GSE127916_1_v_4_nras_human	RummaGEO Gene Perturbation Signatures	1.0	null
CHAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84205
TNPO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56582
TMEM129	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82161
hyperactivity	MGI Mouse Phenotype Associations 2023	1.0	null
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.4008