association	dataset	threshold value	standardized value
MCM3	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN011_HEPG2_24H:D06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17245
CRCGN015_MCF10A_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.4549
methotrexate-1957	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CALM1	Pathway Commons Protein-Protein Interactions	1.0	null
CDK3	Pathway Commons Protein-Protein Interactions	1.0	null
AR	ChEA Transcription Factor Targets	1.0	null
KMS34	CCLE Cell Line Gene Expression Profiles	1.0	1.4298
TUBA8	Pathway Commons Protein-Protein Interactions	1.0	null
AR-25329375-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.941106
ARHGEF6	Pathway Commons Protein-Protein Interactions	1.0	null
TUBB4B	Pathway Commons Protein-Protein Interactions	1.0	null
GSR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00516234
PMC6400843-Table_5.xls-C_FOXM1_Correlated_genes-Ensembl_ID_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.6941
primary motor cortex (area M1, area 4)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.902026
TestisSeminiferousTubule	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.27346
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.1506
GTEX-S4Z8-0926-SM-4AD6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Tcf21	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.5139
BRD-K02301426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21411
MHH-PREB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mrna metabolic process	GO Biological Process Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-6290-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PX3G-0726-SM-48TZT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BRD-K64730221	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73618
Whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
LARP7	Pathway Commons Protein-Protein Interactions	1.0	null
cytoplasmic stress granule	GO Cellular Component Annotations 2023	1.0	null
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.896871
testis_7d	HPA Tissue Sample Gene Expression Profiles	1.0	2.10085
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.57056
BRD-K05125666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.51511
CRCGN016_MCF10A.WT.HP_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.31256
BRD-K46376359	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02236
GTEX-R55F-1226-SM-2TF59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
RPL35	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-A15330900	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30153
H3K9me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MRPL20	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5051-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCBP1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-V1D1-0526-SM-4JBGW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
SNRPD1	Pathway Commons Protein-Protein Interactions	1.0	null
estradiol_homo sapiens_gpl96_gse4668	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GNAL	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K04495110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14912
DNAJC9	Pathway Commons Protein-Protein Interactions	1.0	null
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04232
skeletal muscle	HPA Tissue Protein Expression Profiles	-1.0	-1.42642
BRD-K71274071	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14617
BT-474	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hek293	HPA Cell Line Gene Expression Profiles	-1.0	-1.15677
BRD-K98320707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65298
BRD-K23435841	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67826
IKBIP	Pathway Commons Protein-Protein Interactions	1.0	null
SLFN14	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00616244
EIF3F	Pathway Commons Protein-Protein Interactions	1.0	null
9505BIK	DepMap CRISPR Gene Dependency	1.0	2.14422
GTEX-T2IS-1026-SM-32QP1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-V1D1-1726-SM-4JBHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BCLAF1	Pathway Commons Protein-Protein Interactions	1.0	null
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04313
GTEX-S7SE-0011-R11A-SM-2XCDD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847074
GTEX-NL4W-0011-R4a-SM-2I5GZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25241
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.11207
Gluteal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.548
COLO668	CCLE Cell Line Gene CNV Profiles	1.0	2.60423
UBA52	Pathway Commons Protein-Protein Interactions	1.0	null
TYMS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00428486
PTPRT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00561933
RPL36AL	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-N7MT-1426-SM-3LK5M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-PLZ6-1426-SM-2S1OQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
VMRCRCW	CCLE Cell Line Gene CNV Profiles	-1.0	-1.87027
EIF3E	MSigDB Cancer Gene Co-expression Modules	1.0	null
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.79836
LOXIMVI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FOXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87254
BRD-K11016405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79552
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.69092
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3019
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IK-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF15	Pathway Commons Protein-Protein Interactions	1.0	null
Monocyte_Fetal kidney_Human	CellMarker Gene-Cell Type Associations	1.0	null
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.18631
CRCGN015_HEPG2_48H:F04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.47975
zinc acetate_homo sapiens_gds1617	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ATP1A3	Pathway Commons Protein-Protein Interactions	1.0	null
SERPINA6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00473689
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.922541
ILKAP	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XPT6-2226-SM-4B66R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.024
preoptic region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.92297
HS 940.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.943011
BRD-K37658621	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92794
superior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39846
WDR18	Pathway Commons Protein-Protein Interactions	1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-Row_names_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HADHB	Pathway Commons Protein-Protein Interactions	1.0	null
LIVF001-013	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01707
imatinib_homo sapiens_gpl571_gds3518	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-O5YV-1826-SM-2YUNI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
LONP1	Pathway Commons Protein-Protein Interactions	1.0	null
PDHA1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K25322420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27724
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CCT7	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-R55E-0526-SM-2TC6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A7IN-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BRD-K30065842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3388
COLO 800	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08576
GTEX-QV44-2026-SM-2S1RD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
ME-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.39139
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-7130-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P44H-0011-R8A-SM-2XCEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02848
BRD-K73831546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17898
PPP2CB	Pathway Commons Protein-Protein Interactions	1.0	null
estradiol_homo sapiens_gpl570_gds3217	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-OHPM-0126-SM-2YUN9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.03877
GARS	Pathway Commons Protein-Protein Interactions	1.0	null
PSG6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00567263
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.29018
RPS6KA1	Pathway Commons Protein-Protein Interactions	1.0	null
Cell surface furrow	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.768
mediodorsal nucleus of thalamus_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.908274
ACTN1	Pathway Commons Protein-Protein Interactions	1.0	null
ATR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00682577
deferasirox_homo sapiens_gpl570_gds3558	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RPS11	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XPT6-2126-SM-4B66P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
TUBB4A	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3894
primary motor cortex (area M1, area 4)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.825081
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87148
GTEX-QVUS-0011-R1A-SM-3GAD2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03693
Ovarian disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
COLO800	CCLE Cell Line Gene CNV Profiles	1.0	1.6975
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-5275-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T2IS-1126-SM-4DM6Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
SMARCA5	Pathway Commons Protein-Protein Interactions	1.0	null
primary auditory cortex (core)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.885942
PPM1B	Pathway Commons Protein-Protein Interactions	1.0	null
IKBKB	Pathway Commons Protein-Protein Interactions	1.0	null
SMARCD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00781424
KATNAL2	Pathway Commons Protein-Protein Interactions	1.0	null
P-body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.7
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6933-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100496_FWM_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.3636
BRD-K51448234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38305
GTEX-QDVJ-1226-SM-48U1V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-QEL4-1526-SM-447AB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
testis_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.12979
GTEX-X261-0011-R5A-SM-3NMB4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06421
BEN	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.33036
CRCGN015_MCF10A_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.12105
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
RPS26	Pathway Commons Protein-Protein Interactions	1.0	null
G3BP1	Pathway Commons Protein-Protein Interactions	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-ZJ-A8QQ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRRT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00713035
GTEX-RM2N-0426-SM-2TF4T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
SNB19	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.11469
MV411	CCLE Cell Line Gene Expression Profiles	1.0	1.75461
RIBC2	Pathway Commons Protein-Protein Interactions	1.0	null
ARNT-22903824-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ7-0011-R6a-SM-2I3G7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877126
BRD-K54151058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0403
NKTR	Pathway Commons Protein-Protein Interactions	1.0	null
BL4961 (ABI1)	NURSA Protein Complexes	1.0	null
BRD-K35693854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03394
PMC6097700-pgen.1007515.s008.xlsx-S2_Table-S2_Table_SATB2_Cort_gene-set_list_SATB2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5352183-oncotarget-08-624-s009.xlsx-Table_S20-1_indicates_that_the_gene_is_both_a_TP53-MW_and_a_TP53-MSN_gene_in_the_correponding_cancer_and_0_indicates_not_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GSE182179_0_v_4_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
Oculopharyngodistal myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.631
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
SF3B3	Pathway Commons Protein-Protein Interactions	1.0	null
connective tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
SUFU	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00802028
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Multiple benign melanocytic nevi_Epidermis_GSE3189	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.61433
LEO1	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-73-4670-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K25942808	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.4752
poly-purine tract binding	GO Molecular Function Annotations 2025	1.0	null
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.96773
Muscle thin filament tropomyosin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.877
PMC8798411__F5	PFOCR Pathway Figure Associations 2024	1.0	null
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.1039
CA46	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15988
Prostate adenocarcinoma_PRAD_TCGA-EJ-8469-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CELA2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00759698
CRCGN009_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0359
GTEX-V955-1726-SM-4JBHF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BRD-K19608763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37878
NCIH2073	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70639
Duodenum Mucosa	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.836291
P4HB	Pathway Commons Protein-Protein Interactions	1.0	null
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.862137
MRPS22	Pathway Commons Protein-Protein Interactions	1.0	null
18387200-Genes	GeneSigDB Published Gene Signatures	1.0	null
lateral orbital frontal cortex (area 12/47)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13699
peripheral portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12495
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
Psoas_Muscle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.830603
BRD-K36468214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15457
BRD-K73463737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1795
HS 675.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.82935
medial parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.34722
GTEX-REY6-0526-SM-2TF5M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
CRCGN011_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2758
CRCGN016_MCF10A.WT.HP_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.66092
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01187
Breast Cancer_Mammary Gland Tissue_GSE2429	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.48444
GTEX-RU72-2626-SM-4GIE1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0137
MDA-MB-415	GDSC Cell Line Gene Expression Profiles	-1.0	-3.16819
FAM49A	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K17979415	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03756
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.907935
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YQ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRK-0326-SM-3NB3R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
MED16	Pathway Commons Protein-Protein Interactions	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-PR-A5PF-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BL3734 (CBX4)	NURSA Protein Complexes	1.0	null
SUN2	Pathway Commons Protein-Protein Interactions	1.0	null
Heterochromatin island	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.965
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K72488042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07877
VZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.83867
BRD-K59821372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12906
Brain Lower Grade Glioma_LGG_TCGA-DH-A66D-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05532
DDX17	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K93460493	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60455
GTEX-R55G-1226-SM-48FDC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-NPJ7-0011-R9a-SM-2TC5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09528
TUBA4A	Pathway Commons Protein-Protein Interactions	1.0	null
XPOT	Pathway Commons Protein-Protein Interactions	1.0	null
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.6834
GTEX-RNOR-0426-SM-2TF4U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
HSPA1L	Pathway Commons Protein-Protein Interactions	1.0	null
dorsolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.844217
Eukaryotic translation initiation factor 2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.494
GTEX-RU72-2926-SM-2TF66	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92895
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
3M complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.649
GNA12	Pathway Commons Protein-Protein Interactions	1.0	null
LARS	Pathway Commons Protein-Protein Interactions	1.0	null
SNU201	CCLE Cell Line Gene Expression Profiles	-1.0	-1.97802
BRD-K69349031	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.18577
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.4734
BRD-K31546068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29373
PLAA	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XAJ8-1026-SM-47JY9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
HCT-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50331
HLA-DQA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00805293
COR-L311	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.7952
STK38	Pathway Commons Protein-Protein Interactions	1.0	null
PPP1CA	Pathway Commons Protein-Protein Interactions	1.0	null
RPL12	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN017_MCF10A.TP53.M_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4085
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	1.03715
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.062
MRPL13	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-P4QR-0726-SM-2I5GO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896433
MAP1B	Pathway Commons Protein-Protein Interactions	1.0	null
DLD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00396349
BRD-K32118188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03702
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.171
FCRL6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0040154
GTEX-P4QS-0008-SM-48TDY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
SH3BP1	Pathway Commons Protein-Protein Interactions	1.0	null
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.89469
20124481-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
lung_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.10251
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01801
MED24	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-7109-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K81665173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11277
Acute Myeloid Leukemia_LAML_TCGA-AB-2806-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100417_HIP_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.59743
HCC1195	CCLE Cell Line Gene CNV Profiles	-1.0	-1.72417
RBM43	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K76329122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30334
GTEX-XV7Q-0526-SM-4BRWR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
496100361_TCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.17835
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960512
GTEX-XQ8I-0626-SM-4BOPT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BRD-K25199508	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.44355
Lung squamous cell carcinoma_LUSC_TCGA-77-7139-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC3226433-1756-8935-4-20-S1.XLS-Table_S4_Myc_KD_gene_exp_change-Genes_up-regulated_in_Myc_KD_hESC_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
DDX41	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K88086273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08675
GTEX-SE5C-0526-SM-2XCE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
CRCGN015_HEPG2_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.46249
DAB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0071588
MRPL27	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
ARNT	ChEA Transcription Factor Targets	1.0	null
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44745
BRD-K58245454	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38118
JD-44-KF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.311602
medial mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.24024
TFDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77876
GTEX-SNMC-0126-SM-2XCFO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09542
SK-OV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01181
hsa-miR-4726-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GTEX-QVJO-0011-R5A-SM-2S1QM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22342
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32649
GTEX-U4B1-0226-SM-4DXU8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-QLQ7-1726-SM-2S1QQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
RPL26	Pathway Commons Protein-Protein Interactions	1.0	null
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.22
CRCGN015_MCF10A.TP53.M_24H:E16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1057
BRD-K33767317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35265
AHR-22903824-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
NB-80-IM48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.286285
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ALDH18A1	Pathway Commons Protein-Protein Interactions	1.0	null
testis_7a	HPA Tissue Sample Gene Expression Profiles	1.0	1.5291
BRD-K35296094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21341
hsa-miR-4422	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
Secondary cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.788
AB-33-EM56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.20808
CLTA	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K89377615	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35962
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RQ-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TFEC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4764
TUBB2A	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K12741517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10555
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.8807
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4983-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PDIA6	Pathway Commons Protein-Protein Interactions	1.0	null
Myotonic cataract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.691
primary motor cortex (area M1, area 4)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.892758
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
PDE4C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00589629
CRCGN014_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2381
MDAMB157	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4221
FLG2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XV7Q-1626-SM-4BRWC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BRD-K61440521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10666
Prostate adenocarcinoma_PRAD_TCGA-YL-A8HM-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB33	ENCODE Transcription Factor Targets	1.0	null
GTEX-XBEC-1326-SM-4AT69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-V1D1-1926-SM-4JBGX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.829695
SW1116	CCLE Cell Line Gene CNV Profiles	1.0	2.39936
GTEX-UPK5-0326-SM-3GAF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
RPLP0	Pathway Commons Protein-Protein Interactions	1.0	null
ZR7530	CCLE Cell Line Gene Expression Profiles	1.0	1.83856
A2058	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.963833
RARG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00639733
Dinoflagellate cingulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.785
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z3-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STXBP2	Pathway Commons Protein-Protein Interactions	1.0	null
SIPA1L2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XUZC-0526-SM-4BOPF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
I-II	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.76991
BRD-K65887908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54189
midecamycin-2026	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-NPJ8-0011-R6a-SM-2HMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925216
Lung adenocarcinoma_LUAD_TCGA-78-7158-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WH7G-1026-SM-4LVML	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1PV-01A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K70992537	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44949
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC12664526-CJP2-12-e70055-s001.pdf-4-MECOM_MECOM	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PLZ6-1526-SM-2S1OC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Supramolecular complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
SCAMP3	Pathway Commons Protein-Protein Interactions	1.0	null
NCO2	CCLE Cell Line Gene Expression Profiles	1.0	1.46914
BRD-K39131701	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.88188
GSE166783_1_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-VUSG-1126-SM-4KKZQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33594
GTEX-QEL4-2126-SM-447AE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.573
KYSE-270	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
ZNF644	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46021
Leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.157
GTEX-S4Z8-0726-SM-4GICB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965596
BRD-K90693562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40162
Rectum adenocarcinoma_READ_TCGA-EI-6885-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.5459
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN008_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.3614
BRD-K51790412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27944
GTEX-XGQ4-0526-SM-4AT6C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BRD-K00081911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.0443
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.6749
ESR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.6167
inner CP in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.845983
PMC9529122-pone.0274785.s002.xlsx-S1_Table-S1A_Table_Differentially_expressed_genes_in_HeyA8_overexpressin_ZNF521_vs_HeyA8_control_cells_ZNF521	Rummagene Transcription Factor Associations 2026	1.0	null
DDB1	Pathway Commons Protein-Protein Interactions	1.0	null
17210682-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
GTEX-NFK9-0526-SM-2YUNL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
SMAD4-19686287-HACAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HCC2998	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.4434
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.22921
MOB1A	Pathway Commons Protein-Protein Interactions	1.0	null
CD70	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00470331
CRCGN015_MCF10A.TP53.M_24H:A23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15645
GTEX-TMMY-1326-SM-4DXU9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
SRRM2	Pathway Commons Protein-Protein Interactions	1.0	null
testis_7b	HPA Tissue Sample Gene Expression Profiles	1.0	1.51266
CAPZA2	Pathway Commons Protein-Protein Interactions	1.0	null
III, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06608
GTEX-QCQG-2126-SM-2S1P8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Ribonucleoprotein granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.07
GNAI3	Pathway Commons Protein-Protein Interactions	1.0	null
PRKRA	Pathway Commons Protein-Protein Interactions	1.0	null
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.84007
GTEX-QVUS-0011-R4A-SM-3GAE7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92513
nucleobase-containing compound metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-S95S-1226-SM-4GICG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46619
GTEX-OHPN-0011-R2A-SM-2I5FB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17227
GTEX-RNOR-1426-SM-48FDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.43374
GTEX-S3XE-1526-SM-4AD5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83911
SDC3	Pathway Commons Protein-Protein Interactions	1.0	null
HL-60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.99983
MRPL37	Pathway Commons Protein-Protein Interactions	1.0	null
Ocular motility disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.224
GTEX-PWO3-0011-R6A-SM-2I5F3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26334
hsa-miR-4676-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
NPM1	Pathway Commons Protein-Protein Interactions	1.0	null
Raji	GDSC Cell Line Gene Expression Profiles	1.0	1.80233
GTEX-PLZ6-0426-SM-2I5FG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41269
Prostate adenocarcinoma_PRAD_TCGA-XQ-A8TA-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-S4P3-1126-SM-4AD52	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Cytoplasmic stress granule	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
KPL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0901
GTEX-WRHU-0626-SM-3MJFI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HG-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
doxorubicin_homo sapiens_gpl96_gse12972	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-R55E-0011-R6A-SM-2TC5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16096
GTEX-SUCS-1626-SM-32PLS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.936137
UBA1	Pathway Commons Protein-Protein Interactions	1.0	null
Mrsv	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.508
ADCK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00465766
GTEX-T6MN-0011-R2A-SM-32QOW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.043
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4858-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Nfatc1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.4639
U266B1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61101
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.27774
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03091
Cytoplasmic ribonucleoprotein granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.057
PSMD12	Pathway Commons Protein-Protein Interactions	1.0	null
PKN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00364288
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SLAMF8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00500205
ARR3	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN017_MCF10A.WT.HP_24H:E16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0636
CNOT11	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OXRN-1326-SM-3LK5V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61H-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-4104-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CSNK2A1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-75-7031-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-HS-A5N9-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM129A	Pathway Commons Protein-Protein Interactions	1.0	null
Adductor magnus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.809
CTCF-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-QH-A6CW-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.86333
TEK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00608272
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22933
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-XQ3S-1526-SM-4BOOC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
H3K9me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SK-N-DZ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.831218
ADK	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OHPM-0426-SM-3TW8V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BRD-K42716291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.33642
BRD-K24529791	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35619
ANKFY1	Pathway Commons Protein-Protein Interactions	1.0	null
SF3B2	Pathway Commons Protein-Protein Interactions	1.0	null
SKMEL5	BioGPS Cell Line Gene Expression Profiles	1.0	1.35554
FOXR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82707
HT29	CCLE Cell Line Gene CNV Profiles	1.0	1.77348
BRD-K12864860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19575
CTNNB1	Pathway Commons Protein-Protein Interactions	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.889208
hsa-miR-3647-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
GTEX-XPVG-2226-SM-4B65U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48254
ventrolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.77526
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
ovary	HPA Tissue Protein Expression Profiles	-1.0	-1.42642
MZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.9692
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K70286959	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37662
BRD-K57035236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85186
Extracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
BRD-K54476947	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85509
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN013_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0845
extracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
SUZ12_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XV7Q-2926-SM-4BRUL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-NPJ8-0126-SM-2YUNR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
TUBA1A	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K36298208	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.49512
ILF2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43234
NP8	DepMap CRISPR Gene Dependency	1.0	2.39484
CRCGN014_HEPG2_3H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.664
GTEX-P4PP-0326-SM-33HC4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-OHPN-0011-R4A-SM-2I5FD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16508
ATAD3C	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K94353570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33679
ACVR1C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00634153
GSK3B_knockdown_209_GSE35351	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.47983
NOMO1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K32853527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07807
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.21133
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-13q34_1_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
GSE240386,GSE242143_8_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WFON-0126-SM-4LVM9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BRD-K54112192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.34166
DDX6	Pathway Commons Protein-Protein Interactions	1.0	null
DMS-273	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	3.33785
Ptosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.974
HS-Sultan cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.561
SLC3A2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-A18328003_GDC-0980_HEPG2_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EVSAT	DepMap CRISPR Gene Dependency	1.0	2.19837
BRD-A19766589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70958
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.998559
BRD-K26321439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95376
GTEX-W5X1-0426-SM-3GILB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04227
GTEX-OOBJ-0826-SM-3NB2K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
IL33	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00852438
TRPV4	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-PWO3-1026-SM-2I5F2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23873
GTEX-OXRN-0011-R10A-SM-2I5GC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11363
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Ferroxidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.515
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_30_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
tretinoin_homo sapiens_gpl96_gds3089	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K82619993	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84599
BRD-K07438795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76695
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
TALL1	CCLE Cell Line Gene CNV Profiles	1.0	1.36107
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.11358
RRM1	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7227-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM179B	Pathway Commons Protein-Protein Interactions	1.0	null
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.43374
HGC-27	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.70954
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36154
ZWILCH	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H1435	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.94162
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.914119
BRD-K62555617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9013
GTEX-WRHU-1126-SM-4E3I1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
EPRS	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_14766_KD_HDAC5_SRP265842	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.4324
RPS3	Pathway Commons Protein-Protein Interactions	1.0	null
IPO5	Pathway Commons Protein-Protein Interactions	1.0	null
UACC812	CCLE Cell Line Gene CNV Profiles	-1.0	-1.87307
NCIH1299	CCLE Cell Line Gene Expression Profiles	1.0	1.39496
GTEX-QEL4-1226-SM-447A4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-TSE9-0011-R5A-SM-3DB7J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880162
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.89492
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.32369
stomach	HPA Tissue Protein Expression Profiles	1.0	0.725477
ALOX5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00509536
inferior olive, dorsal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.57228
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26425
MTA2	Pathway Commons Protein-Protein Interactions	1.0	null
PPP1CB	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6937-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Seed coat	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.688
GTEX-PWO3-0011-R3A-SM-2I5EX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18636
MRPL43	Pathway Commons Protein-Protein Interactions	1.0	null
HNRNPH1	Pathway Commons Protein-Protein Interactions	1.0	null
BL2262 (DOCK9)	NURSA Protein Complexes	1.0	null
PSMC6	Pathway Commons Protein-Protein Interactions	1.0	null
primary auditory cortex (core)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.911088
TestisGermCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.05328
MBL2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K36176998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.16308
poly(U) RNA binding	GO Molecular Function Annotations 2025	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HH-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K21412601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8868
Retinitis pigmentosa 62	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.492
GTEX-RM2N-1726-SM-2TF55	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Autosomal dominant cerebellar ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.044
GTEX-QEL4-0526-SM-3GIJ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Brain Lower Grade Glioma_LGG_TCGA-TM-A84T-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T2IS-0626-SM-32QP6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	2.09995
CA SKI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.83309
BRD-K58674774_-666_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CBC2152 (RFWD3)	NURSA Protein Complexes	1.0	null
GTEX-WFJO-0926-SM-4LVM2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GSE76425_0_v_10_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1412
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.83499
GTEX-QMRM-0726-SM-2I5G8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30154
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A9PE-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NPJ8-0011-R7a-SM-2HMJV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989436
NCI-H250	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.79026
BRD-K98355012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25315
CYFIP2	Pathway Commons Protein-Protein Interactions	1.0	null
RPL6	Pathway Commons Protein-Protein Interactions	1.0	null
496100466_PCx_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.43708
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.41753
BRD-K06486611	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34329
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GTEX-QDVJ-0226-SM-2I5FV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13329
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.274
IGROV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EIF2AK4	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K17553044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36504
GTEX-XAJ8-0526-SM-47JYK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-Q2AI-1126-SM-48U19	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Extracellular vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
ROS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00524891
CCT3	Pathway Commons Protein-Protein Interactions	1.0	null
ACTR3	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-5311-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTPS1	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4688-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ALDH1L2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K40418847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1016
CRCGN009_HEPG2_24H:L08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.5445
IL9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00609667
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.4852
RPL4	Pathway Commons Protein-Protein Interactions	1.0	null
nucleus subputaminalis	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.902636
BRD-K38617061	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28136
Cytoplasmic side of nuclear pore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.349
ZRANB2	Pathway Commons Protein-Protein Interactions	1.0	null
SLC25A24	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN017_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03984
GTEX-UJMC-2026-SM-3GADR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BRD-A17831693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36575
GTEX-U4B1-1926-SM-3DB9E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
VPS35	Pathway Commons Protein-Protein Interactions	1.0	null
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02896
posteroventral (inferior) parietal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.825081
RPS17	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K47995281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18841
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-13q34_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN017_MCF10A.WT.HP_24H:J19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8658
PKP3	Pathway Commons Protein-Protein Interactions	1.0	null
salivarygland_6c	HPA Tissue Sample Gene Expression Profiles	1.0	0.988702
BRD-K75606012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57966
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.3816
BRD-K32537206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.132
VCAP	CCLE Cell Line Gene Expression Profiles	1.0	1.56583
NCI-H526	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K45984211	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25369
HEP_3B2_1-7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RPS16	Pathway Commons Protein-Protein Interactions	1.0	null
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.253
GTEX-UJHI-0426-SM-3DB8Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
EEF1G	Pathway Commons Protein-Protein Interactions	1.0	null
Internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.067
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1A6-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.974003
Mesothelioma_MESO_TCGA-MQ-A4LM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K04628654	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19614
GTEX-UJMC-1826-SM-3GADT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-PW2O-0426-SM-48TCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.875468
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.27303
BRD-K92059157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.10401
CCF-STTG1	GDSC Cell Line Gene Expression Profiles	-1.0	-2.4395
GTEX-RU72-0826-SM-46MUS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
NCI H23	BioGPS Cell Line Gene Expression Profiles	1.0	1.00812
PRKDC	Pathway Commons Protein-Protein Interactions	1.0	null
arcuate nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.41644
BRD-K01888220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10931
DBN1	Pathway Commons Protein-Protein Interactions	1.0	null
FBXW11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0054243
OVK-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.05706
IMMT	Pathway Commons Protein-Protein Interactions	1.0	null
FLNB	Pathway Commons Protein-Protein Interactions	1.0	null
ZMPSTE24	Pathway Commons Protein-Protein Interactions	1.0	null
HIST1H1A	Pathway Commons Protein-Protein Interactions	1.0	null
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1509
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	2.24242
ACO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00573414
DDX18	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K01922054	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94115
AP1B1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC7617265-EMS137094-supplement-Supplementary_Tables.xlsx-ST18-gene_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
KCNC3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00801602
Brain Lower Grade Glioma_LGG_TCGA-E1-5318-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.17077
Right_Ventricle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.869059
nucleus of diagonal band	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.947765
BL1569 (TRIM21)	NURSA Protein Complexes	1.0	null
RPS13	Pathway Commons Protein-Protein Interactions	1.0	null
PHGDH	Pathway Commons Protein-Protein Interactions	1.0	null
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	68.4857
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPS2	Pathway Commons Protein-Protein Interactions	1.0	null
TESK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00520304
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
PDCD6IP	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.82048
Acute Myeloid Leukemia_LAML_TCGA-AB-2994-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
k29	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.759
GTEX-PW2O-0526-SM-2I3DX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
FDFT1	Pathway Commons Protein-Protein Interactions	1.0	null
NUP205	Pathway Commons Protein-Protein Interactions	1.0	null
nucleic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.833087
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93119
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EL-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K19020285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45953
BRD-K87939000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03157
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.31224
MAPK1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QLQ7-1526-SM-2S1QA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03104
GTEX-SE5C-2126-SM-4BRUJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GSE236502_2_v_0_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
HNMT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0052546
AARS	Pathway Commons Protein-Protein Interactions	1.0	null
DAUDI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.197
PMC12069319-Table1.xlsx-OCAB_p34_BirA-Gene_Symbol_POU2AF1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K62200014_ANAGRELIDE HYDROCHLORIDE_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K42976515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98543
15902281-TableS1c	GeneSigDB Published Gene Signatures	1.0	null
ARRB2	Hub Proteins Protein-Protein Interactions	1.0	null
BRD-K74109014	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.15281
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SFXN3	Pathway Commons Protein-Protein Interactions	1.0	null
DLST	Pathway Commons Protein-Protein Interactions	1.0	null
HCC1954	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.588456
BRD-K46655163	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.18004
EPB41L5	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
MRPL15	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XUJ4-0526-SM-4BOON	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Tubulin folding cofactor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.377
GTEX-X4EO-2926-SM-4E3JH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BRD-K64075179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32577
exon-exon junction complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.57
MC-IXC	GDSC Cell Line Gene Expression Profiles	-1.0	-1.50062
GTEX-OHPN-0011-R5A-SM-2I5FF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35236
cisplatin_homo sapiens_gds3910	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC9884267-41467_2023_36114_MOESM4_ESM.xlsx-dereg_genes_upon_HMG20A_siRNA_p-Unnamed_0_HMG20A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WK11-0626-SM-3NMAV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
cellular nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
CPNE1	Pathway Commons Protein-Protein Interactions	1.0	null
CD68	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00662986
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.915274
HCC366	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49018
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.374
Gonad	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.067
GTEX-XQ8I-0126-SM-4BOPL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
NCI-H211	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
EEF2	Pathway Commons Protein-Protein Interactions	1.0	null
PMC12069319-Table1.xlsx-OCAB_p40_BirA-Gene_Symbol_POU2AF1	Rummagene Transcription Factor Associations 2026	1.0	null
COPG2	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H650	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PX3G-0426-SM-48U1C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5828
GTEX-UPIC-0726-SM-3GADW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.2298
NCI-H1836	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	3.65262
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GM2313	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.16005
BRD-K34158806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04788
rna metabolic process	GO Biological Process Annotations 2015	1.0	null
CYP4A11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00574698
PMC8040704-jcav12p2673s2.xlsx-Up-regulated_genes_in_EBF1-Unnamed_0_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
PRDX3	Pathway Commons Protein-Protein Interactions	1.0	null
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.81024
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91199
DDX50	Pathway Commons Protein-Protein Interactions	1.0	null
Pollen mother cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.78
GTEX-X88G-0226-SM-4GIE4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983365
GTEX-O5YT-2126-SM-3MJGD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53349
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.26974
hsa-miR-4760-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
L-1236	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ESO51	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN008_HEPG2_24H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.79235
HCFC2	Pathway Commons Protein-Protein Interactions	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.63462
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.40839
IDH2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K36063519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40519
Malignant ovarian germ cell neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.921
BRD-K40175214_torin-1_MCF7_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GNAT3	Pathway Commons Protein-Protein Interactions	1.0	null
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Change_in_both_CSDE1_KD_hESCs-hgnc_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
hel	HPA Cell Line Gene Expression Profiles	1.0	1.01686
hela	HPA Cell Line Gene Expression Profiles	-1.0	-1.94162
spleen	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GTEX-WL46-0726-SM-3LK5Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
RNF123	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00580693
BRD-K99859971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21218
BRD-K15433418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18216
ZNF750_KD_GSE38039_696_human_HaCaT keratinocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SRP14	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K82521348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02465
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.876939
NOLC1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00327
medial geniculate complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.842314
frontal pole, right, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11199
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57721
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17526
periaqueductal gray substance, ventral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.7469
EIF4B	Pathway Commons Protein-Protein Interactions	1.0	null
mRNA metabolic process	GO Biological Process Annotations 2025	1.0	null
GTEX-QDVJ-0926-SM-2I5FU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36747
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
DCTN2	Pathway Commons Protein-Protein Interactions	1.0	null
WM-266-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.8753
UPF1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K89476673	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20812
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7264
SSR1	Pathway Commons Protein-Protein Interactions	1.0	null
rna binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-XMK1-0008-SM-4GICF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03873
ATP5B	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K42181022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49413
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IE-01A-21R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OGDHL	Pathway Commons Protein-Protein Interactions	1.0	null
hydroxyzine-2024	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
LN340	CCLE Cell Line Gene Expression Profiles	-1.0	-1.53379
primary motor cortex (area M1, area 4)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11563
Farage	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.21742
testis_7f	HPA Tissue Sample Gene Expression Profiles	1.0	1.37329
WDR62	Pathway Commons Protein-Protein Interactions	1.0	null
Mobilized_CD34_Primary_Cells_Female	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.929588
GTEX-WHPG-0826-SM-3NMBF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
layer IIIu of area 35r	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.42216
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.862137
IGF2BP2	Pathway Commons Protein-Protein Interactions	1.0	null
ILF3	Pathway Commons Protein-Protein Interactions	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13046
nucleic acid binding	GO Molecular Function Annotations 2015	1.0	null
COPE	Pathway Commons Protein-Protein Interactions	1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
intracellular membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
GTEX-TSE9-0011-R8A-SM-3DB7R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03379
hsa-miR-1182	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.873
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE180468_1_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Adrenocortical carcinoma_ACC_TCGA-PK-A5HA-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.876256
BRD-K52157065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76473
sodium phenylbutyrate-434	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Promastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.146
PSMC3	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN015_MCF10A_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.9258
GCIY	DepMap CRISPR Gene Dependency	1.0	2.13239
BRD-K37262314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61922
POLR2A	ENCODE Transcription Factor Targets	1.0	null
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.65845
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.872608
BRD-K32191695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34563
GTEX-OXRN-0226-SM-2I5EJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40756
PL21	CCLE Cell Line Gene CNV Profiles	1.0	1.34147
PHB	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K91268803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71929
MRPL12	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8427-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K27132686	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70028
EW-13	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.35948
LRRTM4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00559424
ATP4A	Pathway Commons Protein-Protein Interactions	1.0	null
HNRNPF	Pathway Commons Protein-Protein Interactions	1.0	null
HSPB8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00436615
Lung squamous cell carcinoma_LUSC_TCGA-77-7463-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD8	Pathway Commons Protein-Protein Interactions	1.0	null
EVI2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0055533
BRD-K09721123	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07826
Testis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.067
Prostate adenocarcinoma_PRAD_TCGA-VP-A87H-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K21196859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49551
BRD-K37015376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50252
BRD-K32706281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.81527
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.875468
nasopharynx	HPA Tissue Protein Expression Profiles	1.0	1.32548
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15942
LOXL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00361193
Lung squamous cell carcinoma_LUSC_TCGA-22-1011-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_17786_KO_LDBI_SRP071739	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.78644
BRD-K00631971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59297
SRSF2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K92950328	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23777
RDES	DepMap CRISPR Gene Dependency	1.0	5.57547
Motor neuron disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.069
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05784
SRSF5	Pathway Commons Protein-Protein Interactions	1.0	null
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.14037
GTEX-XQ8I-2326-SM-4BOQC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
H3K27me3_iPS-15b	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
central gray of the pons, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.97025
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2827
SUPT20H	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00458096
CCT8	Pathway Commons Protein-Protein Interactions	1.0	null
PSMC4	Pathway Commons Protein-Protein Interactions	1.0	null
PLOD1	Pathway Commons Protein-Protein Interactions	1.0	null
GAPDH	Pathway Commons Protein-Protein Interactions	1.0	null
Hs-766T	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	3.34315
SUM1315MO2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.79067
BRD-K36170990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.4744
molt4	HPA Cell Line Gene Expression Profiles	1.0	1.80757
BRD-K26231789	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0359
BC-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.694
BA-68-FJ41_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.263513
ADRA2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00405146
GTEX-RTLS-0226-SM-2TF5E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-TKQ2-1826-SM-33HB2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865397
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OccipitalLobe	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.00896
BRD-K82504878	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21733
OLIG2-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-OOBJ-1526-SM-3NB1Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
KHDRBS1	Pathway Commons Protein-Protein Interactions	1.0	null
RBBP4	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K59709463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57792
ABCC3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00517943
BRD-A45498368_WYE-125132_HME1_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-5302-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K12492021	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05308
BB65-RCC	GDSC Cell Line Gene Expression Profiles	-1.0	-1.58355
GTEX-QVJO-0126-SM-3GIK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-P4QR-1026-SM-2I5GP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35418
MZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.842706
NCIH929	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35415
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC7A5	Pathway Commons Protein-Protein Interactions	1.0	null
NCIH660	CCLE Cell Line Gene Expression Profiles	1.0	1.50899
ventral tegmental area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.886828
DDOST	Pathway Commons Protein-Protein Interactions	1.0	null
RPL21	Pathway Commons Protein-Protein Interactions	1.0	null
GSK3B_knockdown_158_GSE35351	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.47983
GTEX-OIZI-0626-SM-2XCEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
CBX8	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8I8-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KCNJ8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00615977
BL6566 (KNTC1)	NURSA Protein Complexes	1.0	null
GTEX-QDVJ-0826-SM-48U1S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Lung squamous cell carcinoma_LUSC_TCGA-66-2782-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K84716908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23862
DGKE	Pathway Commons Protein-Protein Interactions	1.0	null
bone marrow	HPA Tissue Protein Expression Profiles	1.0	1.32548
ANKRD44	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00613408
STAT5A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00632484
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.41753
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.4596
HIST1H1C	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K42918627_GSK-2126458_HEPG2_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CHM	Pathway Commons Protein-Protein Interactions	1.0	null
Primary hematopoietic stem cells G-CSF-mobilized Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.17712
Central precocious puberty	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.524
organelle	LOCATE Curated Protein Localization Annotations	1.0	null
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.889878
Brain Lower Grade Glioma_LGG_TCGA-P5-A77W-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Extracellular exosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
PLS1	Pathway Commons Protein-Protein Interactions	1.0	null
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55553
SEMA4G	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00764517
RSL1D1	Pathway Commons Protein-Protein Interactions	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7886-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	176.0
Sarcoma_SARC_TCGA-WK-A8XT-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DHX15	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A632-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PES1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.14037
DGKZ	Pathway Commons Protein-Protein Interactions	1.0	null
CAPAN-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AFG3L2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-NPJ7-0011-R5a-SM-33HBK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845585
primary auditory cortex (core)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.83958
GTEX-XUJ4-0126-SM-4BOP7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Prostate adenocarcinoma_PRAD_TCGA-HC-7213-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
parafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05095
Male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.067
PAN complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.787
GSE149621_2_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV1-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SDHA	Pathway Commons Protein-Protein Interactions	1.0	null
PMC7794364-41540_2020_161_MOESM3_ESM.xlsx-U87MG_Unique_-_PPH2_predictions-Gene_Sym_SMAD9	Rummagene Transcription Factor Associations 2026	1.0	null
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K52094743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03841
Sarcoma_SARC_TCGA-3R-A8YX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gefitinib_homo sapiens_gpl570_gse20854	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76343
TNPO1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K44203030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31842
GTEX-XGQ4-0926-SM-4AT4U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825422
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6473-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Neuron projection cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.653
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48273
SMARCC2	Pathway Commons Protein-Protein Interactions	1.0	null
RPS24	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-A45498368_WYE-125132_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-SIU7-1426-SM-4BRWT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BRD-K26872015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51417
MMP26	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00578218
NCIH2066	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55252
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterine adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.674
SP1	ENCODE Transcription Factor Targets	1.0	null
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95591
Paraspeckles	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.751
GTEX-XGQ4-1326-SM-4GIDU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906171
CAMK2G	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00421541
SIT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00781127
Ribonucleoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.009
BRD-K07895476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49732
BRD-K42918627_GSK-2126458_LNCAP_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SKBR3	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.13143
GTEX-U3ZG-0326-SM-47JXN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
RPS4X	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OXRK-0626-SM-2HMJ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
poly(U) RNA binding	GO Molecular Function Annotations 2023	1.0	null
ARHGAP4	Pathway Commons Protein-Protein Interactions	1.0	null
Rectum adenocarcinoma_READ_TCGA-DY-A0XA-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K49656278	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54021
CRCGN011_HEPG2_24H:I15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6143
GTEX-XOTO-0011-R6B-SM-4B65X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826837
BRD-K63654001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4988
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.4898
DYNC1I2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K22679163	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60962
Skeletal muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.606
SMAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07061
SIN3A	Pathway Commons Protein-Protein Interactions	1.0	null
membrane-bounded vesicle	GO Cellular Component Annotations 2015	1.0	null
GTEX-PSDG-0426-SM-2S1OF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Uterine Carcinosarcoma_UCS_TCGA-NG-A4VU-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SF295	GDSC Cell Line Gene Expression Profiles	-1.0	-1.45459
Prostate adenocarcinoma_PRAD_TCGA-G9-6366-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A_48H:A07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.25328
SCYL1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WVLH-0011-R2A-SM-3MJFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951276
CRCGN015_MCF10A.WT.HP_24H:H20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.00371
CACNA1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00547608
E2F4-21247883-LYMPHOBLASTOID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7276
RPF2	Pathway Commons Protein-Protein Interactions	1.0	null
CDKN1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00594935
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-WZTO-0011-R7B-SM-4E3IS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97772
SCN1A	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-S7SE-0011-R7A-SM-2XCDI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888941
GTEX-TMZS-0326-SM-3DB9P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.81418
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Up_bins-Up_bins_gaining_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-N7MS-0011-R6a-SM-2HMJ4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879354
GTEX-OXRN-0526-SM-2I5EN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34479
NCSTN	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-U3ZH-0326-SM-3DB7A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-PW2O-0826-SM-48TC5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
paclitaxel_homo sapiens_gpl570_gse11550	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K92167240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36684
Brain Lower Grade Glioma_LGG_TCGA-DU-5871-01A-12R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100365_HIP_probable Alzheimer's disease_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.40754
CA-SKI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH1355	CCLE Cell Line Gene CNV Profiles	-1.0	-2.03465
SLAMF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00562996
Gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-WL-A834-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UM-UC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00594
Schizont	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.875
MDAMB436	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.912271
ALDH6A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00880561
GTEX-NL4W-0011-R10A-SM-2I3DY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889157
BRD-K80431395_TRICIRIBINE_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
OV-7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PFKFB3	Pathway Commons Protein-Protein Interactions	1.0	null
Miracidium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.877
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.52605
GTEX-P44H-0726-SM-48TBT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
CHEK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0046307
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.49566
RAF1_activemutant_219_GSE42964	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.5076
amidopyrine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01323
ACOT8	Pathway Commons Protein-Protein Interactions	1.0	null
RBM10	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K74916896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03356
Intersegmental muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.721
SNU449	CCLE Cell Line Gene CNV Profiles	-1.0	-1.83912
GTEX-P78B-1726-SM-3P5ZV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
ARRB2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OHPL-1026-SM-3MJGI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Reservosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.555
doxorubicin_homo sapiens_gpl6947_gse25741	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
bexarotene_homo sapiens_gpl96_gds2777	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EEF1A1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WVLH-0011-R5A-SM-3MJFW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05519
poly-pyrimidine tract binding	GO Molecular Function Annotations 2023	1.0	null
IPO8	Pathway Commons Protein-Protein Interactions	1.0	null
COR-L95	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.13004
17616640-TableS3	GeneSigDB Published Gene Signatures	1.0	null
GTEX-WYJK-1126-SM-3NM9Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XBED-0826-SM-47JYC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-1n_h-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
KCTD12	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K49721311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10532
UBA7	Pathway Commons Protein-Protein Interactions	1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-7966-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RMI2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00714902
intermediate portion of DFC (area 9/46)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.864482
cell part	GO Cellular Component Annotations 2015	1.0	null
GTEX-QDT8-0011-R4A-SM-32PKM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871207
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
W-13-643	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02775
GTEX-N7MT-0326-SM-48TDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-U3ZH-1126-SM-4DXUG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-T6MO-1926-SM-32QOJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
COPB1	Pathway Commons Protein-Protein Interactions	1.0	null
FAM105A	Pathway Commons Protein-Protein Interactions	1.0	null
HT3	DepMap CRISPR Gene Dependency	1.0	3.73878
CLASP2	Pathway Commons Protein-Protein Interactions	1.0	null
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.083
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4890-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SERPINB8	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K94012289_OSI-027_MCF10A_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6948-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K96198015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0674
outer CP in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.40233
outer CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.50012
Spindle Cell Oncocytoma Of The Adenohypophysis	DisGeNET Gene-Disease Associations	1.0	null
nucleus	GO Cellular Component Annotations 2023	1.0	null
ATP6V1A	Pathway Commons Protein-Protein Interactions	1.0	null
PLD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00669347
H3K4me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26425
DLX4	Pathway Commons Protein-Protein Interactions	1.0	null
CTNNA1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-A66025870	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0331
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05497
BRD-K88441035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90396
HNRNPUL1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35358
lateral habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.866005
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DEOC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.16018
tuberomammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15164
GTEX-OHPM-0526-SM-2YUMJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.68724
CNBP	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN015_HEPG2_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.87376
ESR2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-W5WG-2326-SM-3GIJH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
tRNA-splicing ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.574
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
PMC5095001-oncotarget-07-36293-s002.xlsx-Table_S2-Table_S2_MYCN-correlated_genes_and_their_correlations_with_other_transcription_factors_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
single-stranded rna binding	GO Molecular Function Annotations 2015	1.0	null
CAPN1	Pathway Commons Protein-Protein Interactions	1.0	null
MST1R	Kinase Library Tyrosine Kinome Atlas	1.0	95.64
AHR-22903824-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
FAM49B	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K86111620	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88526
GTEX-XQ3S-2526-SM-4BOOG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
RPL19	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93524
CLTB	Pathway Commons Protein-Protein Interactions	1.0	null
XPO1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN008_HEPG2_24H:H02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3457
ZNF750_KD_GDS4599_177_human_HaCaT keratinocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.861948
NCIH1876	CCLE Cell Line Gene Expression Profiles	-1.0	-1.93142
ACTG2	Pathway Commons Protein-Protein Interactions	1.0	null
DPYSL2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE206516,GSE206518_3_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8452624-41467_2021_25709_MOESM12_ESM.xlsx-ST12-Unnamed_2_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q6-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tamoxifen-143	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CAND1	Pathway Commons Protein-Protein Interactions	1.0	null
NPR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00698661
Extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GTEX-QDVJ-1826-SM-2S1P3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21718
EIF4G3	Pathway Commons Protein-Protein Interactions	1.0	null
KG-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.36268
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	53.1318
Brain Lower Grade Glioma_LGG_TCGA-DB-5273-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner CP in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.845446
MKN1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Neonatal myasthenia gravis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
ACTG1	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6953-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.60583
Oocyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.751
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.6724
BRD-K39140255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32502
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26777
FKBP8	Pathway Commons Protein-Protein Interactions	1.0	null
GSE240386,GSE242143_1_v_4_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06516
BRD-K23204256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20519
GTEX-RM2N-0826-SM-48FD3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
POLR1A	Pathway Commons Protein-Protein Interactions	1.0	null
FAM120A	Pathway Commons Protein-Protein Interactions	1.0	null
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Diencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.705
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A642-01A-12R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.146
GTEX-OIZI-1326-SM-3NB1B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
YWHAE	Pathway Commons Protein-Protein Interactions	1.0	null
temporal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.911522
MRPS9	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-A03940741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45428
emetine-hcl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03358
CMK86	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35983
SMARCA4-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN017_MCF10A.TP53.M_24H:D03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.39055
sirolimus_homo sapiens_gpl96_gds2494	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-QLQW-0726-SM-447AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
PDE1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00566633
GTEX-PLZ4-0926-SM-2S1OI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-TMMY-0526-SM-33HBC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Chromatoid body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.573
CPT1A	Pathway Commons Protein-Protein Interactions	1.0	null
PLCPRF5	DepMap CRISPR Gene Dependency	1.0	2.46077
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.95689
MYH9	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-3200-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
OS-RC-2	GDSC Cell Line Gene Expression Profiles	-1.0	-1.46453
MYRF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00960192
AJUBA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00516882
DYNC1H1	Pathway Commons Protein-Protein Interactions	1.0	null
ITGB2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7146-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Zbtb2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.1276
USP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26617
RPS9	Pathway Commons Protein-Protein Interactions	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A4XJ-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K18094884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74414
BRD-K81110981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67318
GTEX-OXRL-1826-SM-2YUMV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-QDT8-0011-R3A-SM-32PKR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892565
IGF2BP1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K74896637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48652
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40347
GSE182680,GSE182683_0_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7115-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
metabolic process	GO Biological Process Annotations 2015	1.0	null
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.852034
BRD-K38571893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18559
BRD-K04061325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25263
nucleus	GO Cellular Component Annotations 2025	1.0	null
BRD-K59221664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46874
Blastoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.608
496100368_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.00578
BRD-K47164766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41623
SW403	DepMap CRISPR Gene Dependency	1.0	6.06898
GTEX-T6MN-1226-SM-3NMA5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
QGP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.949166
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1311
HNRNPD	Pathway Commons Protein-Protein Interactions	1.0	null
MYH10	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WVLH-0011-R6A-SM-3MJFZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944593
Infertility, Male	CTD Gene-Disease Associations	1.0	1.03789
ZNF646	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00803214
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.38302
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CRCGN010_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.33585
RPS5	Pathway Commons Protein-Protein Interactions	1.0	null
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.3512
PCBP1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K33287655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16249
PMC12271601-mmc2.xlsx-OUT_cells_02-Gene_Symbol_TCF23	Rummagene Transcription Factor Associations 2026	1.0	null
HADHA	Pathway Commons Protein-Protein Interactions	1.0	null
KIF5A	Pathway Commons Protein-Protein Interactions	1.0	null
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1936
BEN	GDSC Cell Line Gene Expression Profiles	-1.0	-1.58333
RC-K8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31005
SSB	Pathway Commons Protein-Protein Interactions	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8315-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
M6PR	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_418_KD_EHF_SRP049988	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.5807
GTEX-NPJ8-2626-SM-2D7W2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898213
GTF3C5	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RU72-0011-R5A-SM-2TF6U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874857
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.8907
HNRNPU	Pathway Commons Protein-Protein Interactions	1.0	null
SNU216	DepMap CRISPR Gene Dependency	1.0	2.72766
L428	CCLE Cell Line Gene CNV Profiles	-1.0	-1.66845
SU-DHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.989558
JHU-011	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.83785
WM-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.22171
PTCD3	Pathway Commons Protein-Protein Interactions	1.0	null
COLGALT1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K00853706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43561
OUMS-23	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-U8T8-0126-SM-3DB94	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-XYKS-2426-SM-4AT43	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
KIF5C	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-4A-A93X-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18702
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ATAD1	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	144.565
SNU626	CCLE Cell Line Gene Expression Profiles	-1.0	-2.90107
OGDH	Pathway Commons Protein-Protein Interactions	1.0	null
LMAN2	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-J2-8194-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RVPU-0011-R9A-SM-3NM8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.7804
RD	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.86572
CCT5	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-UTHO-0726-SM-3GAEN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0842
Male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.067
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-FX-A8OO-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PCGF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03756
BRD-K21996934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.50824
PRPF31	Pathway Commons Protein-Protein Interactions	1.0	null
JSC-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.6058
superior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.40098
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.68825
SNU-719	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.913325
GTEX-WFON-0326-SM-3GIKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BRD-K34688736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65199
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.894692
GTEX-OHPN-0011-R7A-SM-2I5FI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26498
rostral (anterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.37712
BRD-K05135707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06691
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
BRD-K34423419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.27256
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GR-06A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PSDG-1526-SM-48TCY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5976-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-V955-1926-SM-4KL1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69751
BRD-K35119180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83301
organelle	GO Cellular Component Annotations 2015	1.0	null
GTEX-T6MO-2026-SM-33HB4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
tamoxifen_macaca fascicularis; macaca mulatta_gpl3535_gse14518	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCC1143	DepMap CRISPR Gene Dependency	1.0	3.31886
SNU626	CCLE Cell Line Gene CNV Profiles	1.0	1.36853
GTEX-SIU8-0526-SM-2XCDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
CLEC2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00564522
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.0
BCAT_GDS748	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A8O6-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KPNB1	Pathway Commons Protein-Protein Interactions	1.0	null
SCC25	DepMap CRISPR Gene Dependency	1.0	2.32928
RIT2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00514941
CRCGN017_MCF10A.WT.HP_24H:M10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0158
Brain Lower Grade Glioma_LGG_TCGA-DU-6396-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
HT115	DepMap CRISPR Gene Dependency	1.0	3.05036
CRCGN017_MCF10A.WT.HP_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6069
MRPL1	Pathway Commons Protein-Protein Interactions	1.0	null
SEC63	Pathway Commons Protein-Protein Interactions	1.0	null
SMAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.517
SKNMC	DepMap CRISPR Gene Dependency	1.0	4.09213
BRD-K64215435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.21605
IGF2BP3	Pathway Commons Protein-Protein Interactions	1.0	null
methotrexate_homo sapiens_gpl570_gse11440	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-V955-1026-SM-4JBHO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
MED4	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09542
Perturb_979_OE_NANOGP8_SRP065951	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.31039
FA-36-VA24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.213366
CRCGN017_MCF10A.WT.HP_24H:J07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0253
mRNA 3'-UTR binding	GO Molecular Function Annotations 2023	1.0	null
16207381-Table1Sa	GeneSigDB Published Gene Signatures	1.0	null
GTEX-TML8-1326-SM-4DXTO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
H3K9me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
layer I of piriform cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.94797
HMEL	CCLE Cell Line Gene Expression Profiles	-1.0	-2.08386
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
LA-42-ER00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.401775
APC2	Pathway Commons Protein-Protein Interactions	1.0	null
CARD9	Pathway Commons Protein-Protein Interactions	1.0	null
PMS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00567381
Transcription factor TFIIA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.756
BRD-K92378241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29358
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.2942
Reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
RPS27L	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QESD-2026-SM-447BI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Perturb_11219_KO_SMYD3_SRP396801	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-19.0
GTEX-U8T8-2226-SM-3DB95	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-OHPM-0326-SM-33HCA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GSE85880,GSE85881_0_v_1_tretinoin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ANXA2	Pathway Commons Protein-Protein Interactions	1.0	null
COPB2	Pathway Commons Protein-Protein Interactions	1.0	null
MS751	DepMap CRISPR Gene Dependency	1.0	3.9041
HIST2H2AB	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K73296134	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08514
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.271
CATSPER2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00593246
GTEX-QLQ7-0726-SM-2I5G2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29592
TRPV4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00620429
PTPN14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36695
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.39482
BRD-K87259147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70221
BRD-K87479423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05113
HF-91-IU60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.310692
GOTO	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.52116
RHOU	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00572178
HSPA5	Pathway Commons Protein-Protein Interactions	1.0	null
IGSF9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00568548
basal nucleus of meynert, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09662
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
valproic acid_homo sapiens_gpl96_gds1050	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	1.0	2.49526
GNAI2	Pathway Commons Protein-Protein Interactions	1.0	null
molecular	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U4-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K15742845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27954
BL5008 (RBM26)	NURSA Protein Complexes	1.0	null
ATP2A2	Pathway Commons Protein-Protein Interactions	1.0	null
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.906921
EZH2	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-7219-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-REY6-0726-SM-2TF4M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BRD-K07667918_linsitinib_MCF7_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-NPJ7-0011-R10A-SM-2I3E5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9272
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-XYKS-2626-SM-4BRUT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
RCC-JW	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.89696
COLO320	CCLE Cell Line Gene CNV Profiles	1.0	1.54607
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Decreased_in_both_CSDE1_KD_hESC-gene_short_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WFON-2526-SM-3LK7P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-XQ8I-0826-SM-4BOOE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
PTBP1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-X638-0326-SM-47JY1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
ATP2B1	Pathway Commons Protein-Protein Interactions	1.0	null
Neuronal ribonucleoprotein granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.953
CRCGN015_HEPG2_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.54396
RPL13A	Pathway Commons Protein-Protein Interactions	1.0	null
DNM2	Pathway Commons Protein-Protein Interactions	1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
GTEX-XOTO-0011-R5A-SM-4B657	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855989
FASN	Pathway Commons Protein-Protein Interactions	1.0	null
lymphoid tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.95759
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8606
H3K27me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MN-60	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QMR6-0011-R6A-SM-32PKP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968743
Eukaryotic translation initiation factor 4F complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.068
BRD-K39078753	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32248
GSE147366_3_v_0_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
NOP10	Pathway Commons Protein-Protein Interactions	1.0	null
Gracilis muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.786
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
COLO 206F	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35862
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MY-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GX-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K31796953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32046
ACTN4	Pathway Commons Protein-Protein Interactions	1.0	null
AP2B1	Pathway Commons Protein-Protein Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A7U8-06A-21R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZNF343	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.8186
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FLNC	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27me3_CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.366
ERH	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K30488928	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.33811
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01603
TE-11	GDSC Cell Line Gene Expression Profiles	1.0	2.37488
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.862137
KNS-42	GDSC Cell Line Gene Expression Profiles	-1.0	-2.3994
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
RNF43	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00826942
a-USP9X (USP9X)	NURSA Protein Complexes	1.0	null
PPT1	Pathway Commons Protein-Protein Interactions	1.0	null
dexamethasone_homo sapiens_gpl3921_gse28896	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K94378105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62596
HCC-56	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Unnamed_13_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7178-01A-21R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACAD11	Pathway Commons Protein-Protein Interactions	1.0	null
OLIG2	ChEA Transcription Factor Targets	1.0	null
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.871807
TMEM104	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00709711
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
POLR1B	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K80816131	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44567
SEC23B	Pathway Commons Protein-Protein Interactions	1.0	null
Thalamus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.47125
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K24669989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.15271
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4355-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LAMTOR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00737548
BRD-K38431962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28259
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3466-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
motor nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.49875
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.834443
sno(s)RNA-containing ribonucleoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.752
GTEX-XUW1-1726-SM-4BOOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
lymphnode_4b	HPA Tissue Sample Gene Expression Profiles	1.0	0.903408
BRD-K00789767	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50344
Caov-3	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.08041
Oligospermia	DisGeNET Gene-Disease Associations	1.0	null
BL1462 (MAD2L1)	NURSA Protein Complexes	1.0	null
CAMK2D	Pathway Commons Protein-Protein Interactions	1.0	null
RALY	Pathway Commons Protein-Protein Interactions	1.0	null
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-RT4-FOXA1_peaks_Context1_2-Nearest_Ensembl_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05264
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.832
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.095
Urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
RNA nuclear export complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.782
anterodorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.968278
Lung adenocarcinoma_LUAD_TCGA-78-7159-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDC5L	Pathway Commons Protein-Protein Interactions	1.0	null
PMC7190674-41467_2020_15815_MOESM3_ESM.xlsx-Tab3-Tab3_Detailed_information_of_the_SRG_mutational_landscape_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NL4W-0011-R6a-SM-2I3GA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07018
CRCGN017_MCF10A.WT.HP_24H:N11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.334
ZNF345	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83371
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TMMY-1226-SM-4DXT6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
ACTN2	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.36377
pcgf2_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.365595
NOP56	Pathway Commons Protein-Protein Interactions	1.0	null
SOX7_OE_GDS3300_123_human_HESC (CA1 and CA2)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
gonad	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
CRCGN011_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.1245
CWC15	Pathway Commons Protein-Protein Interactions	1.0	null
KURAMOCHI	CCLE Cell Line Gene CNV Profiles	1.0	1.67747
GTEX-W5WG-2726-SM-4LMIC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
PMC12956708-DataSheet1.xlsx-Supplementary_Table_6-Supplementary_Table_5_The_DEGs_from_sea_level_between_AMS_and_non-eAMS_group_of_GSE75665_TWIST2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K69932463_AZD8055_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K34234678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98627
BRD-A34891365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42937
17724462-TableS1	GeneSigDB Published Gene Signatures	1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTF3C1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-UTHO-0011-R1A-SM-3GIJO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BRD-K14207150	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18231
BRD-K60437668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21785
GTEX-W5WG-1426-SM-4KKZP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Sarcoma_SARC_TCGA-DX-A8BH-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K43306617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40231
SW403	CCLE Cell Line Gene CNV Profiles	1.0	1.61748
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.33635
SGS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.251
CRCGN011_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6745
sulfasalazine-204	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSN	Pathway Commons Protein-Protein Interactions	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.554
VIM	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K92929998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42537
GTEX-OOBJ-3026-SM-3NB1D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-SE5C-0626-SM-2XCDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5084-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.86205
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	153.594
RPL31	Pathway Commons Protein-Protein Interactions	1.0	null
TTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35869
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IF-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HNRNPK	Pathway Commons Protein-Protein Interactions	1.0	null
nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
AP3D1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K65733046	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69174
hsa-miR-451b	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
GTEX-NPJ7-0011-R2a-SM-2I3GF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846401
GTEX-Q734-0626-SM-2I3EF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GNAO1	Pathway Commons Protein-Protein Interactions	1.0	null
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05851
RARS	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K54099984	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00311
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
P300-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-RUSQ-0526-SM-2TF72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-T5JW-1826-SM-3GAE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
SMN2	Pathway Commons Protein-Protein Interactions	1.0	null
UBA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00651534
DDX1	Pathway Commons Protein-Protein Interactions	1.0	null
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.07009
Uterine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
YWHAB	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A8NY-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-REY6-1026-SM-2TF4Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.671479
NEK9	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K88200990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.42443
Nuclear cap binding complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.302
DAP3	Pathway Commons Protein-Protein Interactions	1.0	null
LRRC59	Pathway Commons Protein-Protein Interactions	1.0	null
GTPBP4	Pathway Commons Protein-Protein Interactions	1.0	null
Transcription preinitiation complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.47
GTEX-R45C-0926-SM-3GAD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
CRCGN017_MCF10A.WT.HP_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4218
NO11	DepMap CRISPR Gene Dependency	1.0	2.39808
Heart Diseases	CTD Gene-Disease Associations	1.0	1.02896
GTEX-XV7Q-2526-SM-4BRV9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
NPC1L1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00582831
CHI3L1	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-5281-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATG7	Pathway Commons Protein-Protein Interactions	1.0	null
Muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.868
CRCGN016_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.37684
GTEX-XAJ8-1226-SM-47JYS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
FIP1L1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE166783_3_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MZ in retrosplenial cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.8722
PMC7818749-12931_2021_1617_MOESM1_ESM.xlsx-TBX4-ENSEMBL_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
dorsomedial hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05803
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.43399
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
estradiol_homo sapiens_gpl570_gse29881	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PSMD2	Pathway Commons Protein-Protein Interactions	1.0	null
Ovarian germ cell cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.62
CRCGN017_MCF10A.WT.HP_24H:N23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.56245
LAN-6	GDSC Cell Line Gene Expression Profiles	-1.0	-2.09809
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.146
GTEX-OXRO-1726-SM-3LK6C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
LIVF001-017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59283
BE-81-QL64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.246542
NSF	Pathway Commons Protein-Protein Interactions	1.0	null
RBM47	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K81586131	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.9283
EF-74-KW12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.234865
EEF1A2	Pathway Commons Protein-Protein Interactions	1.0	null
HSP90AB2P	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OHPL-1626-SM-2HMIR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
RPL22	Pathway Commons Protein-Protein Interactions	1.0	null
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WYVS-1726-SM-3NMAY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Sarcoma_SARC_TCGA-SG-A6Z7-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7818749-12931_2021_1617_MOESM1_ESM.xlsx-TBX4-SYMBOL_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OOBJ-2126-SM-3NB1N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57527
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.8452
subgenual (subcallosal) division of MFC (area 25)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03394
BL1460 (MAD2L1)	NURSA Protein Complexes	1.0	null
PDHB	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
principal sensory nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17442
PFKL	Pathway Commons Protein-Protein Interactions	1.0	null
ATG2A	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RNOR-0526-SM-2TF4O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
SPIN1	Pathway Commons Protein-Protein Interactions	1.0	null
heart_5b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.08663
GTEX-XMK1-2426-SM-4B66I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Brain Lower Grade Glioma_LGG_TCGA-DB-5280-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLXNA4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00666276
APLF	Pathway Commons Protein-Protein Interactions	1.0	null
NCKAP1L	Pathway Commons Protein-Protein Interactions	1.0	null
TRPC5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.006085
HUPT4	CCLE Cell Line Gene Expression Profiles	1.0	1.5524
MCF2L	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K16843478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57585
EBNA1BP2	Pathway Commons Protein-Protein Interactions	1.0	null
inferior frontal gyrus, opercular part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.854984
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.906951
PMC7415402-oncotarget-11-2995-s004.xlsx-EWS-FLI1_Type_2_vs_Type_3-Gene_Symbol_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
IPO7	Pathway Commons Protein-Protein Interactions	1.0	null
MZ in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.927856
GTEX-OOBJ-0326-SM-33HBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-XMK1-2026-SM-4B65K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74023
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
HAT1	Pathway Commons Protein-Protein Interactions	1.0	null
RANGAP1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OHPN-0011-R3A-SM-2I5FC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01234
ARL4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33912
AP3B1	Pathway Commons Protein-Protein Interactions	1.0	null
pineal_night	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.831024
JHH-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.94162
KYM-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-4.68742
poly-purine tract binding	GO Molecular Function Annotations 2023	1.0	null
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.964893
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
ARHGEF2	Pathway Commons Protein-Protein Interactions	1.0	null
ATP1A2	Pathway Commons Protein-Protein Interactions	1.0	null
LANCL1	Pathway Commons Protein-Protein Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3ML-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.850978
SYNCRIP	Pathway Commons Protein-Protein Interactions	1.0	null
CDC16	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-T8EM-0826-SM-4DM76	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BOLA2	Pathway Commons Protein-Protein Interactions	1.0	null
GM1600	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.828968
Prostate adenocarcinoma_PRAD_TCGA-CH-5739-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
testis	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
BRD-K19045069	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99693
intracellular organelle	LOCATE Curated Protein Localization Annotations	1.0	null
CAKI-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.07146
bm93	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.487
GTEX-U3ZN-0826-SM-4DXSZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
CRCGN009_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24237
SART3	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-SNMC-1226-SM-2XCFP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
frontal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01984
hsa-miR-582-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
RBM38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.26942
GTEX-WZTO-0826-SM-3NM8Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-T5JW-1526-SM-4DM5E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
PFKP	Pathway Commons Protein-Protein Interactions	1.0	null
TBL2	Pathway Commons Protein-Protein Interactions	1.0	null
HDAC1	ENCODE Transcription Factor Targets	1.0	null
SLC25A13	Pathway Commons Protein-Protein Interactions	1.0	null
MED27	Pathway Commons Protein-Protein Interactions	1.0	null
17616640-TableS1	GeneSigDB Published Gene Signatures	1.0	null
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	53.1156
LRRC1	Pathway Commons Protein-Protein Interactions	1.0	null
KB-46-EJ60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.251113
BRD-K97052218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.29941
Tonsil	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
inner CP in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.914065
RSV_24Hour_19459069_GSE3397	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.6159
Cytoplasmic stress granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.004
Diazinon	CTD Gene-Chemical Interactions	1.0	null
PMC10319804-41467_2023_38747_MOESM10_ESM.xlsx-circARID1A_KD_genes_up-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.172
WDR77	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RN64-1826-SM-48FDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
INHBC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00701959
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05057
TMEM266	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00613462
KYSE270	DepMap CRISPR Gene Dependency	1.0	3.23858
GTEX-Q2AI-1426-SM-2S1P5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916628
GTEX-O5YW-1526-SM-3MJGL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80701
NRD1	Pathway Commons Protein-Protein Interactions	1.0	null
BL8796 (DAB2IP)	NURSA Protein Complexes	1.0	null
CD8A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0057656
RRBP1	Pathway Commons Protein-Protein Interactions	1.0	null
u138mg	HPA Cell Line Gene Expression Profiles	-1.0	-0.839674
CRCGN015_MCF10A_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.126
BL5315 (POLI)	NURSA Protein Complexes	1.0	null
RPL7	Pathway Commons Protein-Protein Interactions	1.0	null
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08557
HSP90AB1	Pathway Commons Protein-Protein Interactions	1.0	null
MTREC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.847
MOGS	Pathway Commons Protein-Protein Interactions	1.0	null
RSV_4Hour_19459069_GSE3397	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.68517
KRI1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XV7Q-0826-SM-4BRV7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
DOCK8	Pathway Commons Protein-Protein Interactions	1.0	null
DARS	Pathway Commons Protein-Protein Interactions	1.0	null
TPP1	Pathway Commons Protein-Protein Interactions	1.0	null
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58584
NFX1	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-423-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Rectum adenocarcinoma_READ_TCGA-DY-A1DD-01A-21R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PVOW-0626-SM-2XCF6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BRD-K08835142	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93015
CRCGN016_MCF10A.TP53.M_24H:G17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25813
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.936342
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A267-06A-21R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T2IS-0011-R6A-SM-32QP2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96782
Lung squamous cell carcinoma_LUSC_TCGA-63-7023-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3658	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
BRD-K45694673	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42636
Polyadenylate binding protein, human types 1, 2, 3, 4	InterPro Predicted Protein Domain Annotations	1.0	null
LYAR	Pathway Commons Protein-Protein Interactions	1.0	null
PMC6599263-13073_2019_654_MOESM2_ESM.xlsx-CAR1_tsv-gene_name_NR1I3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T8EM-1326-SM-3DB7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
IDH1	Pathway Commons Protein-Protein Interactions	1.0	null
NCIH2196	CCLE Cell Line Gene Expression Profiles	-1.0	-2.53588
PPP1R12A	Pathway Commons Protein-Protein Interactions	1.0	null
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.870739
Small ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.731
PMC9490984-12929_2022_858_MOESM7_ESM.xlsx-MRF-GeneSymbol_MYRF	Rummagene Transcription Factor Associations 2026	1.0	null
MRPL16	Pathway Commons Protein-Protein Interactions	1.0	null
RPL29	Pathway Commons Protein-Protein Interactions	1.0	null
Sarcoma_SARC_TCGA-DX-A1KY-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100380_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.51322
CRCGN015_MCF10A.TP53.M_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.129
H3K27me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-4716-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
PMC10158025-ijbsv19p2081s6.xlsx-SupTable5-ZBTB20_ZBTB20	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.96859
FXR2	Pathway Commons Protein-Protein Interactions	1.0	null
PDE4B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00460511
VZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.869391
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPM1A	Pathway Commons Protein-Protein Interactions	1.0	null
Cytosolic small ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.562
RNA metabolic process	GO Biological Process Annotations 2023	1.0	null
PRMT1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QV31-1326-SM-2S1QE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83958
GTEX-X5EB-0626-SM-46MVQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
PRPH	Pathway Commons Protein-Protein Interactions	1.0	null
PRSS53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94571
GTEX-PVOW-0011-R5A-SM-32PL7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10471
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.11096
CEP89	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00636756
GTEX-S4Q7-1426-SM-3K2B9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A5UE-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMC1A	Pathway Commons Protein-Protein Interactions	1.0	null
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21929
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85897
CRCGN014_HEPG2_3H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.4832
GTEX-R55G-0826-SM-2TC5U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834807
BRD-K75807957	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0084
IPO9	Pathway Commons Protein-Protein Interactions	1.0	null
Pellicular membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.864
GTEX-WWYW-0011-R6A-SM-3NB3G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866539
cyclosporine_homo sapiens_gpl570_gse15935	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GOLGA3	Pathway Commons Protein-Protein Interactions	1.0	null
TemporalLobe	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.94566
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PREPL	Pathway Commons Protein-Protein Interactions	1.0	null
planum temporale, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.925652
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.43619
COLO-792	GDSC Cell Line Gene Expression Profiles	-1.0	-1.75441
Brain Lower Grade Glioma_LGG_TCGA-CS-5390-01A-02R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPL3L	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-4778-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
PAICS	Pathway Commons Protein-Protein Interactions	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2912-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SF3A1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RVPU-2426-SM-2XCAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
CDK13	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-POYW-1126-SM-48TCI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A9PD-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPL27A	Pathway Commons Protein-Protein Interactions	1.0	null
SERPINH1	Pathway Commons Protein-Protein Interactions	1.0	null
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45406
BRD-K36782804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12269
extracellular region part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CRCGN008_HEPG2_24H:E14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5453
HCC1438	CCLE Cell Line Gene Expression Profiles	-1.0	-2.31074
GTEX-PLZ4-1226-SM-2I5FE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37363
L3MBTL3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00637248
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X8HC-1626-SM-46MWE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.00157
BRD-K64055724	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19061
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0243
ASB2	Pathway Commons Protein-Protein Interactions	1.0	null
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.99418
nucleoside phosphate binding	GO Molecular Function Annotations 2015	1.0	null
HSPA1B	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-V955-2026-SM-3GAFA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82571
GTEX-XUJ4-1426-SM-4BONT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
ZBED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40533
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.254
SQRDL	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-A61767497	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02527
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7004
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K24599650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66881
BRD-K17234088	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71823
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0317
DICER1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OXRK-1626-SM-3NB17	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Hypothalamus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.828975
RNPEP	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-VJWN-0426-SM-3GIJI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
MRPL40	Pathway Commons Protein-Protein Interactions	1.0	null
Prdm15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.4144
GTEX-S341-1826-SM-3K2AB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
TRIM24	Pathway Commons Protein-Protein Interactions	1.0	null
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.107
BL7507 (SOS1)	NURSA Protein Complexes	1.0	null
ATP2B3	Pathway Commons Protein-Protein Interactions	1.0	null
PMC7921413-41467_2021_21650_MOESM5_ESM.xlsx-002_DE-CD34_Blasts_AP1_low_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
USP15	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K33194123	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22044
BRD-K27870441	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27614
GTEX-VJYA-1426-SM-4KL1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55292
RPS23	Pathway Commons Protein-Protein Interactions	1.0	null
RPS3A	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K54639145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05197
Epimastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.067
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.842485
GTEX-OHPN-0011-R11A-SM-2I5FM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04795
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19J-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MN-0011-R4A-SM-32QPG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18206
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
BRD-K57719270	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05786
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-A5HU-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cerebellar ataxia type 47	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.046
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.379
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31126
CHCHD2P9	Pathway Commons Protein-Protein Interactions	1.0	null
HTRA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00531635
GTEX-QESD-0526-SM-2I5G5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851504
BRD-K01978082	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37975
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19952
BRD-K29661539	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06155
NCI-H2869	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.26841
Head and Neck squamous cell carcinoma_HNSC_TCGA-C9-A480-01A-12R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K12909905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47155
PMC7895828-41419_2021_3488_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_3_List_of_deregulated_genes_in_c-MYC_altered_human_HCC_from_TCGA_LIHC_dataset_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8567280-EMBR-22-e53014-s008.xlsx-PC3_TIP5_bound_promoter-Unnamed_4_BAZ2A	Rummagene Transcription Factor Associations 2026	1.0	null
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K96845170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40637
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.295
ESO51	DepMap CRISPR Gene Dependency	1.0	8.95732
TBX2-33478486-IMR90-HUMAN-LUNG	ChEA Transcription Factor Targets 2022	1.0	null
496100438_PCx_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.62944
Muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.076
BRD-K09017160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33211
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5430-01A-02R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
KIAA0196	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K58964288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.53533
GTEX-PWO3-0011-R5A-SM-2I5EZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04734
BHLHE23	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7378
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
OCUM1	CCLE Cell Line Gene CNV Profiles	1.0	1.47046
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7098
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4860-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1283	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5258-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K07530355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19376
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
CISD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00507483
BRD-K02395808	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2115
BRD-K24263752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20089
MAP4	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.888653
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.0817
hsa-miR-4477a	TargetScan Predicted Conserved microRNA Targets	1.0	0.293524
Large ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.258
GTEX-PX3G-1526-SM-48U11	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21793
BRD-K52416366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96937
KNS42	CCLE Cell Line Gene Expression Profiles	-1.0	-1.8468
Erg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.4132
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ACTBL2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K13543055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48496
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BRD-K74251295	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51386
BRD-K89338336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21069
AHR	ChEA Transcription Factor Targets	1.0	null
XPO7	Pathway Commons Protein-Protein Interactions	1.0	null
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.84522
GTEX-XXEK-1026-SM-4BRUW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BRD-K25127909	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33668
BRD-K47083242	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17248
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4167
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10937
MYL6	Pathway Commons Protein-Protein Interactions	1.0	null
HCC70	DepMap CRISPR Gene Dependency	1.0	9.15759
BRD-K78809123	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42608
SKMEL28	BioGPS Cell Line Gene Expression Profiles	1.0	0.869769
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K01951210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89236
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36154
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.273
mRNA metabolic process	GO Biological Process Annotations 2023	1.0	null
GTEX-XXEK-0426-SM-4BRVW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BRD-K23361743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13085
BRD-K50660797_EPICATECHIN MONOGALLATE_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CAL-120	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZU-06A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YWHAH	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-SNOS-1026-SM-4DM4Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
cloning	GeneRIF Biological Term Annotations	1.0	null
Eukaryotic translation initiation factor 3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.767
GTEX-QDT8-0926-SM-32PL2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
TRIP13	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OXRL-1626-SM-2YUMU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
PSMD13	Pathway Commons Protein-Protein Interactions	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00091
BRD-K01853144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33635
HOS	GDSC Cell Line Gene Expression Profiles	-1.0	-1.50844
RPS6KA3	Pathway Commons Protein-Protein Interactions	1.0	null
FTSJ3	Pathway Commons Protein-Protein Interactions	1.0	null
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.8173
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.922541
GTEX-PWO3-0011-R8A-SM-2I5GD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19816
GTEX-RUSQ-0926-SM-47JWU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
CGN	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN015_HEPG2_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.8008
JA-85-SW39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.341465
Sporocyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.89
TP53BP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00546896
GTEX-RM2N-0326-SM-48FD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-POYW-0526-SM-2XCEY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
BRD-K83045795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08413
GTEX-VJYA-0826-SM-4KL1M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BRD-K72351789	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69288
GTEX-N7MT-0011-R7a-SM-2I3FZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840015
GTEX-R53T-2026-SM-3GIJF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
NCL	Pathway Commons Protein-Protein Interactions	1.0	null
RBMXL2	Pathway Commons Protein-Protein Interactions	1.0	null
methotrexate_homo sapiens_gpl96_gse5118	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XUW1-0426-SM-4BOOT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
ELMSAN1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-O5YV-1126-SM-3LK73	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A7IP-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPL7A	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-P44H-0011-R10A-SM-2XCEK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843274
GTEX-UPJH-0926-SM-4IHKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-PLZ5-1526-SM-3P5ZX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5102
BRD-K56939159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23044
Kinetoplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.821
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36154
GTEX-QV31-0626-SM-447C5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
CAOV4	DepMap CRISPR Gene Dependency	1.0	3.04595
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.66395
SAG	Pathway Commons Protein-Protein Interactions	1.0	null
NBPF8	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K61189585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59883
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	96.0898
BRD-K63957636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39129
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K17420784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95914
GTEX-QXCU-0006-SM-2TC5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02924
BRD-K06146578	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34037
GTEX-REY6-0426-SM-2TF5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
DNM1L	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN015_HEPG2_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.75683
ESR2	Hub Proteins Protein-Protein Interactions	1.0	null
GNB2L1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.31735
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
poly(A) binding	GO Molecular Function Annotations 2025	1.0	null
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.123
SLC2A4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00595681
RARA_KD_GDS4065_42_human_MCF-7	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K9me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q734-1926-SM-2I5EV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25121
RPL23A	Pathway Commons Protein-Protein Interactions	1.0	null
RPL23	Pathway Commons Protein-Protein Interactions	1.0	null
RERF-LC-MS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.942065
BD-04-NG34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.22176
ATL3	Pathway Commons Protein-Protein Interactions	1.0	null
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.088
DNM1	Pathway Commons Protein-Protein Interactions	1.0	null
MRPL53	Pathway Commons Protein-Protein Interactions	1.0	null
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.851363
Congenital Absence Of Germinal Epithelium Of Testes	DisGeNET Gene-Disease Associations	1.0	null
U-698-M	GDSC Cell Line Gene Expression Profiles	1.0	2.51574
Left_Ventricle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.863834
KMRC2	DepMap CRISPR Gene Dependency	1.0	3.50859
KO52	CCLE Cell Line Gene Expression Profiles	1.0	1.6121
BRD-K23844489	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23518
CLNS1A	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K44950949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34386
PABPC5	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QDVJ-1726-SM-2I5FX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32297
VDAC2	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-L3-A524-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K08408085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33558
BRD-K67566344_KU-0063794_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ATP2A3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K85580909	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42303
BRD-K84788922	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24998
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.869204
BRD-K25709301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69994
BRD-K32018176	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25126
PAK1IP1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
17210682-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
LCP1	Pathway Commons Protein-Protein Interactions	1.0	null
SNU489	CCLE Cell Line Gene Expression Profiles	-1.0	-1.84684
CRCGN013_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.37615
DAUDI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.40756
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.575
RNA degradation	KEGG Pathways 2026	1.0	null
GTEX-P78B-0526-SM-2I5F7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19009
MOLM13	CCLE Cell Line Gene Expression Profiles	1.0	2.48798
supraoptic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.907303
CHSA8926	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NRIP1	Pathway Commons Protein-Protein Interactions	1.0	null
GSPT1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42108
GMPS	Pathway Commons Protein-Protein Interactions	1.0	null
HT-115	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.59957
extracellular region part	GO Cellular Component Annotations 2015	1.0	null
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06318
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.2627
EIF3H	Pathway Commons Protein-Protein Interactions	1.0	null
TMOD3	Pathway Commons Protein-Protein Interactions	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A6RY-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DNAJA1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	1.0	2.07221
ctnnb1_19652203_myeloma_lof_human_gpl570_gds3578	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.090673
RPS18	Pathway Commons Protein-Protein Interactions	1.0	null
lateral habenular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.82441
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A57G-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.081
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.041
Microspore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.516
CDK7	Pathway Commons Protein-Protein Interactions	1.0	null
SLC22A4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00700109
nucleus	LOCATE Curated Protein Localization Annotations	1.0	null
GSE148262,GSE150691_1_v_0_hdlbp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-UJMC-0426-SM-4IHJF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-XQ3S-0008-SM-4GIDZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938671
GTEX-V1D1-2626-SM-4JBJH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-QDVJ-1426-SM-48U1Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
DIMT1	Pathway Commons Protein-Protein Interactions	1.0	null
WSU-FSCCL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31144
CCT2	Pathway Commons Protein-Protein Interactions	1.0	null
LRRC8C	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XOTO-2826-SM-4B65I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
MT-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31005
TNPO2	Pathway Commons Protein-Protein Interactions	1.0	null
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.196
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Translation initiation complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.726
GTEX-XOTO-0526-SM-4B662	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-XUJ4-0008-SM-4BOQI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844156
extracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-OHPM-1826-SM-2YUNF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
kidney	HPA Tissue Protein Expression Profiles	-1.0	-0.808876
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.206
DOHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.922506
LIN28B	Pathway Commons Protein-Protein Interactions	1.0	null
vitamin c_homo sapiens_gpl570_gse11919	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-QVUS-0011-R9A-SM-3GIJA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984889
CA46	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.955885
OPLAH	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H1734	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.827221
DLGAP4	Pathway Commons Protein-Protein Interactions	1.0	null
JAK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00636792
SU-DHL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15988
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.5001
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.201
BL5345 (PTPN12)	NURSA Protein Complexes	1.0	null
GTEX-OOBJ-1826-SM-3NB1C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BRD-K45097650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06383
Cronkhite-Canada syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.484
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	47.4545
Pole plasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.162
FLG	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	1.0	2.30207
DDX39A	Pathway Commons Protein-Protein Interactions	1.0	null
NCIH2171	CCLE Cell Line Gene Expression Profiles	-1.0	-1.76269
GTEX-WFG8-0626-SM-3GILJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BRD-K35383890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.6524
GTEX-SNMC-0626-SM-4DM6H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.12467
ADRBK2	Pathway Commons Protein-Protein Interactions	1.0	null
extracellular vesicular exosome	GO Cellular Component Annotations 2015	1.0	null
vincristine_homo sapiens_gpl570_gse7556	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-X62O-0126-SM-4E3JN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
PMC3708595-NIHMS474972-supplement-1.pdf-8-MYB_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K53257307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23391
BRD-K91467861	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84715
VZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05621
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.58218
CRCGN011_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5073
ANAPC5	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K90872016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40919
BRD-K30589514	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.49446
GM2493	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.33868
BRD-K26163290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29875
PSMD14	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XOTO-0826-SM-4B65O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.093
P30-OHK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-UPIC-0926-SM-4IHLV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
NAP1L1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K42139332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44897
RPS6KA2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-U8T8-0326-SM-3DB93	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K45979235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53548
BRD-K29597572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3649
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.9631
OVCAR-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE240386,GSE242143_8_v_4_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.1658
small molecule binding	GO Molecular Function Annotations 2015	1.0	null
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45234
SKUT1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56306
HARS	Pathway Commons Protein-Protein Interactions	1.0	null
KIF5B	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4766-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Small saphenous vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.158
mediodorsal nucleus of thalamus_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.874842
ATP1A4	Pathway Commons Protein-Protein Interactions	1.0	null
NCIH1792	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32235
superior parietal lobule, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.871564
TIG3TD	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61735
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.5563
BRD-K15019832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05362
BRD-K11105500	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02375
BRD-K12460566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29686
RPL24	Pathway Commons Protein-Protein Interactions	1.0	null
HIST1H1E	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF326	Pathway Commons Protein-Protein Interactions	1.0	null
SURF4	Pathway Commons Protein-Protein Interactions	1.0	null
precommissural nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.41182
BRD-K34798837	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69432
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.66136
BRD-K36252987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10499
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_3_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K22139757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.25776
head and face region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23924
GART	Pathway Commons Protein-Protein Interactions	1.0	null
posterior group of nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.23394
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.54097
hsf1_17216044_hela_lof_human_gpl571_gds1733	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	1.06604
H3K27me3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RTLS-0426-SM-2TF5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Prostate adenocarcinoma_PRAD_TCGA-EJ-7783-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K83845379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50636
GFPT1	Pathway Commons Protein-Protein Interactions	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5L4-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QV44-2226-SM-447A3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Stomach disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.037
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.2997
CRCGN015_HEPG2_48H:I06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.24632
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48273
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZH-2126-SM-3NB1P	GTEx Tissue Sample Gene Expression Profiles	1.0	2.15197
GTEX-S341-1626-SM-3K2B8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975539
GTEX-WYJK-1026-SM-3NM8W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.29396
SP1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WCDI-0426-SM-4GIAL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861869
RAJI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.92722
APP	Pathway Commons Protein-Protein Interactions	1.0	null
CLTC	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN010_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.04825
GTEX-U3ZH-1526-SM-4DXV1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56121
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09641
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7432-11A-01R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-H4-A2HO-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Distal myopathy with rimmed vacuoles	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.317
SA1-27219007-CHIP-SEQ-ERYTHROID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCIH716	CCLE Cell Line Gene CNV Profiles	1.0	1.47147
male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Stomach cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.005
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-TSE9-0526-SM-3DB7Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
ATP1A1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K54260552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.1271
GTF3C4	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K05118964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.27836
CD4_Memory_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.12046
hsa-miR-1915	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
BRD-K04546974	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63951
OCI-AML5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.84538
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6097-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K37433647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.34103
BRD-K00557942	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.22104
HNRNPCL1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WZTO-0011-R5B-SM-3NMC5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05916
PAOX	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00447057
ACLY	Pathway Commons Protein-Protein Interactions	1.0	null
RIMS4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00475727
Alkyl hydroperoxide reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.513
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1707
MRPL19	Pathway Commons Protein-Protein Interactions	1.0	null
BZW2	Pathway Commons Protein-Protein Interactions	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.949507
SW1463	CCLE Cell Line Gene CNV Profiles	1.0	1.52059
CCT6A	Pathway Commons Protein-Protein Interactions	1.0	null
imatinib_homo sapiens_gpl96_gds3048	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-VUSG-2726-SM-4KKZJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
A172	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.07574
BL5433 (ERCC6)	NURSA Protein Complexes	1.0	null
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.896155
AGO1	Pathway Commons Protein-Protein Interactions	1.0	null
OVMANA	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60696
GTEX-V1D1-0626-SM-4JBHN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
TMPO	Pathway Commons Protein-Protein Interactions	1.0	null
MRPS28	Pathway Commons Protein-Protein Interactions	1.0	null
C11orf84	Pathway Commons Protein-Protein Interactions	1.0	null
MRPL44	Pathway Commons Protein-Protein Interactions	1.0	null
HNRNPH3	Pathway Commons Protein-Protein Interactions	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YR-01A-12R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K75143842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.2456
BRD-K39649723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39255
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-R55G-0126-SM-48FDS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-SSA3-0226-SM-32QPN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865735
BL7356 (WDR89)	NURSA Protein Complexes	1.0	null
BRD-K61247793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28256
Lung squamous cell carcinoma_LUSC_TCGA-85-A4QQ-01A-41R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H460	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	3.51968
GTEX-PWO3-0926-SM-2I5EY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09439
GTEX-XXEK-1826-SM-4BRVC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NF-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TUBB3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00622531
RBM25	Pathway Commons Protein-Protein Interactions	1.0	null
RPL18	Pathway Commons Protein-Protein Interactions	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NR-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WEE1_druginhibition_307_GSE38972	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.43268
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
H1FX	Pathway Commons Protein-Protein Interactions	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.15561
ZR-75-30	GDSC Cell Line Gene Expression Profiles	1.0	2.12929
Uterine Carcinosarcoma_UCS_TCGA-NG-A4VW-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5151-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.TP53.M_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.12274
Nuclear speck	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.132
BRD-K75815721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06115
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8636-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K11247495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02309
MED17	Pathway Commons Protein-Protein Interactions	1.0	null
CUL3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00569293
GEMIN2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K05950670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67928
Metacyclic form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.964
BRD-K69487461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65767
HNRNPC	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-S3XE-1626-SM-3K2AJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05491
heart_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.868207
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.4582
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IM-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VUSG-0926-SM-3GIK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
H3K4me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC12069319-Table1.xlsx-OCAB_WT_BirA-Gene_POU2AF1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WHSE-0926-SM-3NMBS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
mRNA cap binding complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.417
CANX	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-T2IS-2226-SM-4DM65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
hsa-miR-186	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
POLE3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00413696
AGO1	Hub Proteins Protein-Protein Interactions	1.0	null
DHX9	Pathway Commons Protein-Protein Interactions	1.0	null
RPL32	Pathway Commons Protein-Protein Interactions	1.0	null
mRNA binding	GO Molecular Function Annotations 2023	1.0	null
BRD-K98758203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.14215
Cytoplasmic side of Golgi membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.987
Ribonucleoprotein granule	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10758
DCD	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-R55D-0626-SM-3GAD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
CNOT3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K76068355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91541
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.98812
BRD-K41287744	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2963
FOXA1	JASPAR Predicted Transcription Factor Targets	1.0	null
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.25821
MRPS27	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07459
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.685307
Lymphatic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.144
Prostate adenocarcinoma_PRAD_TCGA-HC-8216-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNH1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K38380337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11407
CRCGN017_MCF10A.TP53.M_24H:K17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01996
SCN5A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00484999
CRCGN015_MCF10A_48H:D08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.27641
PRKACB	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K03935681	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23884
SC-596 (CCNA2)	NURSA Protein Complexes	1.0	null
CRLF2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00801815
GTEX-OHPN-2726-SM-2I5H4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08345
hsa-miR-1208	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.085
Exoribonuclease complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.883
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.559
Daudi	GDSC Cell Line Gene Expression Profiles	1.0	2.5055
BRD-K99034771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0243
HSPD1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC6961462-NIHMS1544104-supplement-Sup_Tab.xlsx-Sup_Table_3_a-Supplementary_Table_3_Genes_Regulated_by_A_MYB_in_Humans_and_Macaques_Bold_genes_with_reduced_expression_in_Group_3_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Liver hepatocellular carcinoma_LIHC_TCGA-RG-A7D4-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K34931072	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.76979
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.498
BRD-K95963125	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2395
lateral hypothalamic area, tuberal region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09987
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LD-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COPRS	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-NL4W-0011-R5a-SM-2I3GD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957572
CUL4A	Pathway Commons Protein-Protein Interactions	1.0	null
cuneus, right, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11227
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.368
SPIN3	Pathway Commons Protein-Protein Interactions	1.0	null
ATP6V1H	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.13348
Hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.011
MZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.53179
LS513	CCLE Cell Line Gene CNV Profiles	1.0	1.66458
GTEX-R55E-0011-R9A-SM-2TC6C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840889
nucleus coeruleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.85588
BL5826 (ORC6L)	NURSA Protein Complexes	1.0	null
ARHGEF7	Pathway Commons Protein-Protein Interactions	1.0	null
LIMA1	Pathway Commons Protein-Protein Interactions	1.0	null
MAP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00452019
496100281_HIP_probable Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0492
BRD-K32208085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85772
GTEX-POYW-0826-SM-2XCEM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
CRCGN008_HEPG2_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01455
RPS29	Pathway Commons Protein-Protein Interactions	1.0	null
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.959235
PMC12315868-Supplemental_Data_S1.xlsx-Supplemental_Data_S1F-TP53_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QVUS-0226-SM-3GIJY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-RN64-0726-SM-48FCV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40392
DYNC1LI2	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5097-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A7LX-01A-12R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.8955
BRD-K51275565	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12582
BRD-K65780164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88579
GTEX-T6MN-0426-SM-32PMF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
RERFLCSQ1	DepMap CRISPR Gene Dependency	1.0	3.39673
BRD-K84693638	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06338
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.54415
hsa-miR-513a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
CRCGN015_MCF10A_48H:H03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06205
GTEX-RUSQ-0326-SM-47JWS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
NET1_KD_GDS4196_437_human_AGS - gastric adenocarcinoma cells - (65 shRNA Knock-Down)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
MCF 10A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.832753
ATP6V1B2	Pathway Commons Protein-Protein Interactions	1.0	null
lateral orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16629
female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GTEX-WH7G-1526-SM-4LVMX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BRD-K27849471	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02463
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
adipose tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GTEX-S7SE-0011-R5A-SM-2XCDA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11376
GOLGA4	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-10a-5p	MiRTarBase microRNA Targets	1.0	null
GTEX-QDT8-2926-SM-32PKC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21397
GTEX-QMR6-0011-R2A-SM-32PKV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.998891
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.26963
CCAR1	Pathway Commons Protein-Protein Interactions	1.0	null
DMS-273	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RPL18A	Pathway Commons Protein-Protein Interactions	1.0	null
4star	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.04421
GTEX-X3Y1-2026-SM-3P5YM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.00157
BRD-K37740343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0107
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEG5-0926-SM-2TC64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-U3ZM-1626-SM-4DXSK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58129
caudal group of intralaminar nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.986194
Prostate adenocarcinoma_PRAD_TCGA-EJ-7789-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-T2-A6X2-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17999
PRR4	Pathway Commons Protein-Protein Interactions	1.0	null
E2F4-21247883-LYMPHOBLASTOID-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
MRPS14	Pathway Commons Protein-Protein Interactions	1.0	null
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ACK	Kinase Library Tyrosine Kinome Atlas	1.0	97.42
PSMD3	Pathway Commons Protein-Protein Interactions	1.0	null
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.893078
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.56251
GTEX-WFON-2026-SM-4LVMW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49348
GNAS	Pathway Commons Protein-Protein Interactions	1.0	null
Endodeoxyribonuclease complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.577
PMC11003700-pbio.3002240.s013.xlsx-siMYCN_RNA_IMR32_48h_q_0_05_1_5-Table_S6_Genes_commonly_and_differentially_regulated_by_MYCN_and_WDR5_in_IMR32_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
RPL13AP3	Pathway Commons Protein-Protein Interactions	1.0	null
SLC1A5	Pathway Commons Protein-Protein Interactions	1.0	null
TINF2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00751245
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CAPN2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-R55C-0726-SM-48FCN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15689
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
trovafloxacin_homo sapiens_gpl96_gse9166	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K70695911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87276
BRD-K18346873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90771
CRCGN017_MCF10A.TP53.M_24H:K18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.41193
NECTIN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00717485
dm15	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.165
RNAi effector complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.35
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63463
BRD-K92826631	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16726
CRCGN015_HEPG2_48H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.40793
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
RPLP1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-P4PP-1626-SM-2HMJF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
NCI-H1092	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	3.1895
GTEX-O5YV-0526-SM-2I5GE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41165
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5E-Down_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
temporal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.28753
MFSD2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00487323
BRD-K66754362	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22112
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.19825
MYO3B	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K09777330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00828
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.60778
inferior frontal gyrus, orbital part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.984326
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RPS19	Pathway Commons Protein-Protein Interactions	1.0	null
BUB3	Pathway Commons Protein-Protein Interactions	1.0	null
RPL3	Pathway Commons Protein-Protein Interactions	1.0	null
SMARCA4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00527996
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K91876603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.12577
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.856242
GTEX-S341-1026-SM-4AD71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
superior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.911932
GTEX-OOBJ-1626-SM-2I3F7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.31778
OPM-2	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.09563
BRD-K06830450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0494
SUPT6H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68747
T84	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.13614
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.28303
BRD-K66889220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.34736
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13494
GTEX-WHWD-0326-SM-3LK6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-RNOR-0011-R4A-SM-3GAD3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88517
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Trypanosomoid form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.366
cellular process	GO Biological Process Annotations 2015	1.0	null
FAR1	Pathway Commons Protein-Protein Interactions	1.0	null
DBT	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K95521279	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24617
GTEX-V1D1-1226-SM-4JBI5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69409
RISC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.36
LAS1L	Pathway Commons Protein-Protein Interactions	1.0	null
BPI	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00529096
BRD-K45272675	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.47598
INCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86595
BRD-A54769817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26322
BRD-K26479796	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.26462
PCBP2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XOTO-0008-SM-4GICE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03074
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47X-01A-31R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RMDN3	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5677-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K98153780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03584
OCI-AML2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.27809
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.994691
BRD-K26273412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23112
MYC_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUZC-1326-SM-4BRV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07338
MDA-MB-436	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.07986
NCIH1650	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44255
SKNFI	CCLE Cell Line Gene Expression Profiles	-1.0	-1.74066
BRD-K88934376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12932
GTEX-XBEC-1526-SM-4AT68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-WQUQ-0006-SM-3MJF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964034
VIIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.869122
CALU1	CCLE Cell Line Gene CNV Profiles	-1.0	-3.20482
GTEX-REY6-0626-SM-2TF4G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BRD-K26552461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.32835
MZ in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.46054
PSMD6	Pathway Commons Protein-Protein Interactions	1.0	null
meta1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.664
medial superior olive	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.72462
BRD-K14823121	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41896
Pancreas	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.8485
CRCGN011_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3631
CD1D	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00720241
Essential tremor 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.342
BRD-K54420800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15152
ERGIC3	Pathway Commons Protein-Protein Interactions	1.0	null
Liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43N-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K92433763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42583
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
CRCGN015_MCF10A.TP53.M_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.96045
CRCGN009_HEPG2_24H:F20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.239
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ACTB	Pathway Commons Protein-Protein Interactions	1.0	null
OS252	DepMap CRISPR Gene Dependency	1.0	4.70447
BRD-K61335814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80865
GTEX-OXRO-0011-R10A-SM-2I5EH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02273
COPA	Pathway Commons Protein-Protein Interactions	1.0	null
SK-UT-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3603
TUBB3	Pathway Commons Protein-Protein Interactions	1.0	null
AKAP8	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-U3ZN-1426-SM-3DB87	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
RB1_KD_GSE50532_627_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
MYBBP1A	Pathway Commons Protein-Protein Interactions	1.0	null
CHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.972183
SNRPD2	Pathway Commons Protein-Protein Interactions	1.0	null
midbrain reticular formation	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.978676
FLT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00706315
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XBED-2226-SM-47JYQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
poly-purine tract binding	GO Molecular Function Annotations 2015	1.0	null
CTPS2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K29850806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3059
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.976772
MORCPR	DepMap CRISPR Gene Dependency	1.0	2.29237
ARRB1	Pathway Commons Protein-Protein Interactions	1.0	null
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02029
IARS	Pathway Commons Protein-Protein Interactions	1.0	null
YWHAQ	Pathway Commons Protein-Protein Interactions	1.0	null
primary motor cortex (area M1, area 4)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10626
Small nuclear ribonucleoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.194
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.870739
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-gene_id_x_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.82197
AKAP9	Pathway Commons Protein-Protein Interactions	1.0	null
organic cyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-RN64-0326-SM-2TC5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.246
extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-POMQ-0008-SM-48TE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
PIK3R4	Pathway Commons Protein-Protein Interactions	1.0	null
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03637
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Tou	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.609
BRD-K72468471	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09297
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.94162
HEATR3	Pathway Commons Protein-Protein Interactions	1.0	null
FARAGE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.47689
GALK1	Pathway Commons Protein-Protein Interactions	1.0	null
EVSA-T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
A704	CCLE Cell Line Gene Expression Profiles	-1.0	-1.81839
GTEX-TSE9-0011-R7A-SM-3DB7P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.928885
Amastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.187
SLC12A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00752205
TestisLeydigCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.32974
GTEX-XUW1-1026-SM-4BONY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K37092508	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31991
CRCGN017_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.13635
GTEX-OXRL-0326-SM-2I3F2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GUCY1A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00496025
SLC7A6	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K95500312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44629
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7351
Sarcoma_SARC_TCGA-Z4-A9VC-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NDUFS1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K25485483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61983
CRCGN015_MCF10A.WT.HP_24H:A18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.20035
BRD-A52749901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48093
BCHE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00850371
MRPL23	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21964
CNN1	Pathway Commons Protein-Protein Interactions	1.0	null
BL759 (BANP)	NURSA Protein Complexes	1.0	null
PATU8902	CCLE Cell Line Gene Expression Profiles	1.0	1.46473
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.19516
Cytoplasmic ribonucleoprotein granule	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Decreased_in_both_CSDE1_KD_hESC-hgnc_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HIST1H2BO	Pathway Commons Protein-Protein Interactions	1.0	null
MRPL49	Pathway Commons Protein-Protein Interactions	1.0	null
GSE165334_2_v_0_dabrafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20194
GTEX-R55F-1526-SM-2TF4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A953-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPS8	Pathway Commons Protein-Protein Interactions	1.0	null
CC-61-HH09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.277623
extracellular vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.057922
globus pallidus, internal segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.4951
BRD-K35587518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12372
LRPPRC	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K96745500	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.15345
OLIG2-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K74803017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92355
GTEX-SNOS-1126-SM-4DM67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86972
ATXN2L	Pathway Commons Protein-Protein Interactions	1.0	null
ATP2A1	Pathway Commons Protein-Protein Interactions	1.0	null
MATR3	Pathway Commons Protein-Protein Interactions	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2822-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12069319-Table1.xlsx-OCAB_p34_BirA-Gene_POU2AF1	Rummagene Transcription Factor Associations 2026	1.0	null
basal nucleus of Meynert	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.950832
P31FUJ	CCLE Cell Line Gene CNV Profiles	1.0	1.89339
dorsolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00383
GTEX-TMMY-1026-SM-4DXTI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A3F3-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Germ plasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.122
GTEX-WWYW-0526-SM-3NB2W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
RXF393	BioGPS Cell Line Gene Expression Profiles	1.0	1.49047
ALYREF	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-O2-A52N-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Change_in_both_CSDE1_KD_hESCs-gene_short_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WFG7-1326-SM-4LMK1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BRD-K94082609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25163
CSE1L	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K58407898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15591
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2025	1.0	null
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.7041
NAT10	Pathway Commons Protein-Protein Interactions	1.0	null
AIMP1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-S33H-0126-SM-4AD62	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75769
KE-37	GDSC Cell Line Gene Expression Profiles	1.0	1.80126
RPN2	Pathway Commons Protein-Protein Interactions	1.0	null
NCOA3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K61491580	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09884
GTEX-SSA3-0326-SM-32QPS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BRD-K85567359	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14544
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.2096
Trypomastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.533
WIBG	Pathway Commons Protein-Protein Interactions	1.0	null
MRPS31	Pathway Commons Protein-Protein Interactions	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A556-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRE	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
HSP90AA1	Pathway Commons Protein-Protein Interactions	1.0	null
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.5833
MCF7	DepMap CRISPR Gene Dependency	1.0	2.03499
BRD-K59841546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36252
BL1691 (MAD1L1)	NURSA Protein Complexes	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WO-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K66216147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.39108
hsa-miR-502-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GTEX-QEG5-1226-SM-447AR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
HSPA6	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H2141	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.40798
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BM-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NPJ8-0011-R3a-SM-2HMIW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88082
PMC12069319-Table1.xlsx-OCAB_p35_BirA-Gene_Symbol_POU2AF1	Rummagene Transcription Factor Associations 2026	1.0	null
BV173	CCLE Cell Line Gene Expression Profiles	1.0	1.57377
BAG6	Pathway Commons Protein-Protein Interactions	1.0	null
MRPL48	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K67979704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03887
NCI-H1793	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SERBP1	Pathway Commons Protein-Protein Interactions	1.0	null
Breast Neoplasms	CTD Gene-Disease Associations	1.0	1.34227
17023574-TableS1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-R53T-1826-SM-3GIJX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-PLZ6-1626-SM-3NB23	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GFPT2	Pathway Commons Protein-Protein Interactions	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7289-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-5128-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.434
GTEX-QEG5-0226-SM-2I5GI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43355
DDX21	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K75900952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65256
CRCGN015_MCF10A_48H:M15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22055
BL8804 (STIL)	NURSA Protein Complexes	1.0	null
BRD-K15047839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.14019
BL1245 (MAML3)	NURSA Protein Complexes	1.0	null
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K54837534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94659
THOC6	Pathway Commons Protein-Protein Interactions	1.0	null
PSMD7	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K92144896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74106
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SLC25A12	Pathway Commons Protein-Protein Interactions	1.0	null
viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
vesicle	GO Cellular Component Annotations 2015	1.0	null
HSP90AA4P	Pathway Commons Protein-Protein Interactions	1.0	null
TLR8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00618096
ZBTB33_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VUSG-0726-SM-3GIK1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BL8346 (KIAA1688)	NURSA Protein Complexes	1.0	null
SkeletalMuscle	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.92573
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29403
MRPL2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-PVOW-0426-SM-2XCF8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
PABPC1L	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XYKS-2526-SM-4BOPX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BRD-K09975370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16925
RPS7	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WVLH-0011-R11A-SM-3MJFO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-PWCY-1726-SM-48TD3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
hsa-miR-3133	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79595
BRD-K31300534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20161
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TUBAL3	Pathway Commons Protein-Protein Interactions	1.0	null
SPRR1B	Pathway Commons Protein-Protein Interactions	1.0	null
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	128.002
cytoplasmic stress granule	GO Cellular Component Annotations 2025	1.0	null
ATP2B4	Pathway Commons Protein-Protein Interactions	1.0	null
EBF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00573827
RPS25	Pathway Commons Protein-Protein Interactions	1.0	null
hematopoietic system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
tail of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0087
GTEX-O5YW-1826-SM-2YUN2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-X4XX-0011-R6B-SM-46MWP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01066
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2H0-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
White sponge nevus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.492
salivary gland	HPA Tissue Gene Expression Profiles	1.0	1.53289
PABPC4	Pathway Commons Protein-Protein Interactions	1.0	null
EFTUD2	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H1694	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	3.53074
BRD-K84334677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08964
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
LBR	Pathway Commons Protein-Protein Interactions	1.0	null
BL5892 (MAP4K4)	NURSA Protein Complexes	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8405-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IKZF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00428579
BRD-K31939603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45369
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.1781
SMARCA4	ChEA Transcription Factor Targets	1.0	null
Head muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.083
BRD-K90697691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15226
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.274
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.801
SLC22A5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00628598
SR	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.19088
NCI-H630	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CAT	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RWSA-0626-SM-2XCBD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
SMAD4	ChEA Transcription Factor Targets	1.0	null
Lymphatic system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.108
BRD-K30643363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04661
H3K4me1_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
red nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.883889
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23402
BRD-K89967940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56377
GTEX-QCQG-1226-SM-48U23	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
AHCY	Pathway Commons Protein-Protein Interactions	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A6MB-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RU72-0011-R6A-SM-2TF71	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841507
Lung adenocarcinoma_LUAD_TCGA-64-5779-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K94247332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80654
BRD-K38557728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01232
TRPV5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00505264
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4422-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.845665
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70337
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_downreg-human_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4759	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.12
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.66608
GTEX-W5WG-2226-SM-4LMI3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Schinzel Giedion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.177
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6226
PTGER3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00676098
BRD-K23204014	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22962
BRD-K60337657	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68765
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BRD-K15714104	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39245
GTEX-XYKS-0226-SM-4BRW3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
RPL11	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-REY6-1226-SM-48FDR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
TUBA1C	Pathway Commons Protein-Protein Interactions	1.0	null
HTATSF1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC10363146-41598_2023_38681_MOESM1_ESM.pdf-403-PROX2_PROX2	Rummagene Transcription Factor Associations 2026	1.0	null
CAPZA1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-X4EP-3226-SM-3P5YR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
POLD1	Pathway Commons Protein-Protein Interactions	1.0	null
HPAFII	DepMap CRISPR Gene Dependency	1.0	5.67883
GTEX-XBED-0526-SM-47JY3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
XRCC5	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XV7Q-1326-SM-4BRWM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.85226
XPO4	Pathway Commons Protein-Protein Interactions	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A6W2-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
liver	HPA Tissue Protein Expression Profiles	-1.0	-1.42642
NAMALWA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.898832
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K80239721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20437
thyroid_5d	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.84065
posteroventral (inferior) parietal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.853714
tylosin-tartrate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23215
NCIH508	CCLE Cell Line Gene CNV Profiles	1.0	2.3174
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04209
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02491
BRD-K81660107	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01972
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.3225
CRCGN015_MCF10A_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.0764
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25842
Brain Lower Grade Glioma_LGG_TCGA-CS-4943-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K52613522	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07018
OCI-AML3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.51947
Lung adenocarcinoma_LUAD_TCGA-97-7547-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PSDG-0826-SM-48TCZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-X62O-2226-SM-46MW3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Adrenocortical carcinoma_ACC_TCGA-OR-A5LJ-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN011_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3093
PRKAG1	Pathway Commons Protein-Protein Interactions	1.0	null
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.62
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.70242
BRD-K43979194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2383
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
WDR26	Pathway Commons Protein-Protein Interactions	1.0	null
DRD4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00764583
ribavirin_homo sapiens_gpl570_gds4391	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.0899
CSNK1G2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00417807
LOVO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TP63_01_196	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59875
G3BP2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
k562clones	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.572
SAM complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.012
oculomotor nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.997061
BRD-K35780971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13875
BRD-K30214140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11382
GSE205729,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K34256721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0772
BRD-K75410936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13687
GTEX-WYJK-0426-SM-3NM9G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
mRNA cleavage and polyadenylation specificity factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.9
FGFR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00505743
CS-9665B (CASP3)	NURSA Protein Complexes	1.0	null
BRD-K84690141	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53161
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-V1D1-2426-SM-3GAER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
ALDH2	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8341-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
TUBA3C	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-58-A46L-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular aromatic compound metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-UJHI-1726-SM-3DB9B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
AA-11-RO46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.264775
zinc acetate_homo sapiens_gpl570_gds1617	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-K7-AAU7-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPL15	Pathway Commons Protein-Protein Interactions	1.0	null
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0044
GTEX-QMRM-0926-SM-447BR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BRD-K40175214_torin-1_A375_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-TSE9-0011-R6A-SM-3DB7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16076
Prdm14	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.5983
GTEX-QEG5-0426-SM-2I5GJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993639
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-1.04988
Extraocular muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.933
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20039
CRCGN015_HEPG2_48H:C18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23596
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09557
SYNGAP1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XLM4-0011-R9A-SM-4AT45	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-VJYA-1326-SM-3GIJC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BRD-K32471649	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86559
BRD-K32617235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14788
SNUC1	CCLE Cell Line Gene CNV Profiles	1.0	1.83841
Kidney Chromophobe_KICH_TCGA-KO-8406-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDR2L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00621466
CRCGN010_HEPG2_24H:B09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.51962
GTEX-T5JW-0326-SM-4DM6J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Huntington's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.025
GTEX-XPVG-0726-SM-4B658	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.46276
GTEX-T6MN-1126-SM-4DM71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Perisynaptic extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.759
BRD-K15975627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93335
GTEX-UJHI-1126-SM-4IHLN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
SW1417	COSMIC Cell Line Gene Mutation Profiles	1.0	null
STS-0421	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6407-01A-13R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K73114074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40363
membrane-bounded vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
posterior (caudal) superior temporal cortex (area 22c)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.44141
BRD-K27154831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65725
KF-18-RY71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.383215
Nuclear pore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.351
FAF2	Pathway Commons Protein-Protein Interactions	1.0	null
SBC-3	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.84378
IMPDH2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CAL120	DepMap CRISPR Gene Dependency	1.0	2.29191
TMEM132B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79562
BRD-K22280519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14506
GTEX-XK95-0008-SM-4AT5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
UBR5	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QEL4-1326-SM-447AD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
RAB11FIP5	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN011_HEPG2_24H:A22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.44925
Sertoli cell-only syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.267
BRD-K88620071	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69934
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DHCR24	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-S95S-0008-SM-4AT5M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
hsa-miR-450b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
ATAD3A	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-5277-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K92981306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68743
NR2C1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00498595
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
OVCAR8	CCLE Cell Line Gene CNV Profiles	-1.0	-1.85322
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
CRCGN016_MCF10A.TP53.M_24H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.31607
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
medial mammillary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14895
HNRNPL	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-R55G-2526-SM-2TC6D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876816
Sarcoma_SARC_TCGA-PT-A8TR-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K64730761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66265
JAK1_activemutant_61_GSE18239	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.57486
posteroventral (inferior) parietal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.911589
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19541
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.372
GTEX-XQ3S-0126-SM-4BOO9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
CSNK1A1L	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K43206373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69136
Lung	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.18681
GTEX-QEG5-0826-SM-2I5GF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3316
GTEX-XUW1-0826-SM-4BOP6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Lung adenocarcinoma_LUAD_TCGA-95-7562-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFG8-1926-SM-4LVM1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74734
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.98516
FUT4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00467313
SUZ12	ENCODE Transcription Factor Targets	1.0	null
daudi	HPA Cell Line Gene Expression Profiles	1.0	1.58636
CRCGN017_MCF10A.TP53.M_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.5061
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4859
inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.865525
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.34577
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-RT4-FOXA1_peaks_Context1_2-Gene_Name_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
heterocyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
U-266	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	3.18605
CPSF6	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K40175214_torin-1_HME1_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SRF	JASPAR Predicted Transcription Factor Targets	1.0	null
PMC11976705-cbm-22-266-s008.pdf-6-GLI1_GLI1	Rummagene Transcription Factor Associations 2026	1.0	null
NRF2-31884422-A549-HUMAN-LUNG-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
BRD-K31187110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20692
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.416
ESR1	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H520	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.0442
CTTN	Pathway Commons Protein-Protein Interactions	1.0	null
UBE2E2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00581934
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
FLNA	Pathway Commons Protein-Protein Interactions	1.0	null
RPL8	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OXRP-0526-SM-2I3EW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-V1D1-0326-SM-4JBIY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
organic cyclic compound metabolic process	GO Biological Process Annotations 2015	1.0	null
STAT3	Pathway Commons Protein-Protein Interactions	1.0	null
Rectus femoris	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.693
BRD-K26208451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31991
Female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.226
mRNA surveillance pathway	KEGG Pathways 2026	1.0	null
hydrocortisone_homo sapiens_keloid scar_gds3071	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K33956641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24752
extracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-6682-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
THP-1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.47877
BRD-K85162396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19291
Amyotrophic lateral sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.098
EJM	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.11264
smooth muscle	HPA Tissue Protein Expression Profiles	-1.0	-1.42642
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q1-06A-21R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE161864,GSE161866_4_v_3_ror2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K26402831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14458
H3K9me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.054
TIMM50	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K57902040	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54005
UOK101	DepMap CRISPR Gene Dependency	1.0	2.32659
SubthalamicNucleus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.941776
GTEX-OHPL-0326-SM-33HC8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
supramammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.34226
Poisoning	CTD Gene-Disease Associations	1.0	1.03901
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0802
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.833471
DHX30	Pathway Commons Protein-Protein Interactions	1.0	null
Glycosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.728
GTEX-U412-0326-SM-3DB9L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
A3-KAW	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.24873
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.158
GTEX-P78B-0926-SM-2I5FA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39921
GTEX-U3ZH-1926-SM-4DXTR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
TAB1	Pathway Commons Protein-Protein Interactions	1.0	null
SYNE1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00619
ABCD1	Pathway Commons Protein-Protein Interactions	1.0	null
CTNND1	Pathway Commons Protein-Protein Interactions	1.0	null
CYP3A5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00668046
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.956407
GRK6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00527779
HSPA8	Pathway Commons Protein-Protein Interactions	1.0	null
DKC1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC6400843-Table_5.xls-C_FOXM1_Correlated_genes-Symbol_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U8XE-1126-SM-3DB8W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.00275
KO52	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-X261-1026-SM-3NMDL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
CWC27	Pathway Commons Protein-Protein Interactions	1.0	null
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.13439
BRD-K48999921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10396
PMC8481886-Table_2.xlsx-A_subsets-common_MSC_AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
BBIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83871
TUFM	Pathway Commons Protein-Protein Interactions	1.0	null
Ribonucleoprotein complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
PMC5059470-ncomms12992-s6.xlsx-CRS-NOCRS-Supplementary_Data_5_Integration_Frequency_in_cirrhotic_CRS_and_non-cirrhotic_no-CRS_Tumor_Samples_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
NAA10	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K67740871	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60002
KMS-28BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.976938
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AP-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K27973265	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89215
ARHGAP21	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.4192
RDH12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00681979
CingulateCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.858468
SUM159PT	DepMap CRISPR Gene Dependency	1.0	2.90259
BRD-K77541177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59879
TNFRSF13B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0055023
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21051
GTEX-N7MT-0011-R5a-SM-2I3G6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18746
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	1.0	2.40215
GTEX-V955-0926-SM-4JBJ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
HUG1N	CCLE Cell Line Gene Expression Profiles	1.0	1.82763
SW948	CCLE Cell Line Gene CNV Profiles	1.0	2.26703
LPCAT1	Pathway Commons Protein-Protein Interactions	1.0	null
MDAMB134VI	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49575
Nrf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.431
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.864896
Polysome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.78
BRD-K85901675	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14878
ctnnb1_21914722_ls174t_lof_human_gpl570_gds4386	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.228548
CFL1	Pathway Commons Protein-Protein Interactions	1.0	null
SND1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC2866657-pone.0010547.s001.xls-ERG-high-GENES_UPREGULATED_IN_ERGhigh_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
extracellular vesicle	GO Cellular Component Annotations 2015	1.0	null
CCND2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00818861
HSP90B1	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7145-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K16432886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27602
GTEX-WH7G-0426-SM-3NMBJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BL3961 (PES1)	NURSA Protein Complexes	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4FD-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UJHI-0326-SM-4IHJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
SFTPC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00666564
MYO1E	Pathway Commons Protein-Protein Interactions	1.0	null
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.12
GTEX-PSDG-0726-SM-2I5FN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20966
SUM102PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.811599
Cytosol	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
PROSER2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K02053819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12525
GTEX-UJMC-0726-SM-3GADX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BRD-K25907192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35293
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.22
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4918-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE30	CCLE Cell Line Gene Expression Profiles	1.0	2.27273
TECR	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K44139185	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95194
ChaGo-K-1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.05454
AP2A1	Pathway Commons Protein-Protein Interactions	1.0	null
COLO-829	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CORO7	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K40252598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29312
SPTAN1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QVUS-2826-SM-3GADB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02816
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.88559
frontal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.60383
TCOF1	Pathway Commons Protein-Protein Interactions	1.0	null
imatinib_homo sapiens_gpl571_gds4175	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.906921
BRD-K86143816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38464
BD-49-MD69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.276875
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.90234
QARS	Pathway Commons Protein-Protein Interactions	1.0	null
AUTS2-25519132-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.771
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04699
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3346-01A-01R-1766-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.52672
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7438-01A-21R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33825
LPCAT2	Pathway Commons Protein-Protein Interactions	1.0	null
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3179
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fusome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.904
BL1739 (CARM1)	NURSA Protein Complexes	1.0	null
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.4285
BRD-K64434200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.34915
GSE149621_3_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Transcription factor TFIIF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.514
GTEX-XK95-1026-SM-4GIDV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24601
SCFD2	Pathway Commons Protein-Protein Interactions	1.0	null
RPS4Y1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-PLZ5-0726-SM-2I5F9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25303
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.832499
GTEX-R55G-2326-SM-2TC61	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
KG1	CCLE Cell Line Gene Expression Profiles	1.0	1.64128
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FS-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Translation preinitiation complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.819
KYSE410	CCLE Cell Line Gene Expression Profiles	1.0	1.67622
POLR1C	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-TKQ2-0826-SM-33HB6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
ANG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00535142
SMYD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00362659
Hypothalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.705
H3K4me1_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-T5JW-0926-SM-4DM5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3308-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BRD-K50315405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58734
MRPS7	Pathway Commons Protein-Protein Interactions	1.0	null
SVEC4-10 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.784
BRD-K42918627_GSK-2126458_MCF7_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SIG-M5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.42194
NCI-H1944	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.910058
BRD-K39223744	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44023
PSMC5	Pathway Commons Protein-Protein Interactions	1.0	null
A4-Fuk	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.70822
MZ in posterodorsal (superior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21735
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40114
lateral parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.75021
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-BI-A0VS-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular part	GO Cellular Component Annotations 2015	1.0	null
GTEX-Q734-0226-SM-48U1A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
D341MED	CCLE Cell Line Gene Expression Profiles	1.0	2.32287
EIF4G1	Pathway Commons Protein-Protein Interactions	1.0	null
TUBB8	Pathway Commons Protein-Protein Interactions	1.0	null
GFAP	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-UPK5-0226-SM-3GAEV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
RPS15A	Pathway Commons Protein-Protein Interactions	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6YC-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
U1 snRNP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.968
PRKACA	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K67750179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46368
SW1116	COSMIC Cell Line Gene CNV Profiles	1.0	2.76305
CLOCK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00459309
GTEX-XGQ4-2026-SM-4AT6G	GTEx Tissue Sample Gene Expression Profiles	1.0	2.20073
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06853
GTEX-R55D-0126-SM-48FEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61228
GTEX-P4QS-0426-SM-3NMCQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-SE5C-1526-SM-4BRWU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
MRPL9	Pathway Commons Protein-Protein Interactions	1.0	null
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CSTF3	Pathway Commons Protein-Protein Interactions	1.0	null
TestisIntersitial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.66793
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21194
outer CP in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.912946
BL5899 (NIN)	NURSA Protein Complexes	1.0	null
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.296
cisplatin_homo sapiens_gpl570_gds3910	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K36064145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94168
GTEX-Q734-1626-SM-48U1B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
C1QBP	Pathway Commons Protein-Protein Interactions	1.0	null
RPL36	Pathway Commons Protein-Protein Interactions	1.0	null
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03891
EBNA1-20929547-CHIP-SEQ-RAJI-CELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCIH1436	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40838
BRD-K13941175	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46693
ERLIN1	Pathway Commons Protein-Protein Interactions	1.0	null
heart_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.64469
GTEX-PX3G-0326-SM-2I3EO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
MRPL38	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VP-A875-01A-31R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24614
HT55	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EXOC5	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K85919350	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.97678
BRD-K13715646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54049
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03253
posteroventral (inferior) parietal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.58525
CAP1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-WFG8-1726-SM-4LVM6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-OHPK-0326-SM-2HMJO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GSE226355,GSE226357_3_v_4_ybx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.09367
posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07589
Casparian strip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.085
BRD-K11571815	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08636
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
CYP1A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00671029
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.82084
ADRBK1	Pathway Commons Protein-Protein Interactions	1.0	null
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00786
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.55289
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RBM14	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K34311186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2353
NCI-H748	COSMIC Cell Line Gene CNV Profiles	1.0	2.76305
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context1_2-Gene_Name_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
PTRH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00547922
BD-61-OO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.248169
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5698-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-283	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ovary	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
PTK2B	Pathway Commons Protein-Protein Interactions	1.0	null
PPP5C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00379918
19658189-TableS4	GeneSigDB Published Gene Signatures	1.0	null
PARK2	Pathway Commons Protein-Protein Interactions	1.0	null
ABC1	CCLE Cell Line Gene CNV Profiles	1.0	1.61787
GTEX-Q2AH-0326-SM-48U1K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
ARNT-22903824-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC7415402-oncotarget-11-2995-s004.xlsx-EWS-FLI1_Type_1_vs_Type_2-Gene_Symbol_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TKQ1-1126-SM-4GIAZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13055
GTEX-QDVN-0926-SM-2I5GL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36781
BL1868 (TRIP4)	NURSA Protein Complexes	1.0	null
ALAD	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-UTHO-0011-R3A-SM-3GIK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A2OS-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
zona incerta	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.969737
ventral tegmental area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.948386
MED13	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H2228	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06318
SLFN11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00626857
HDLBP	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6943-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MED1	Pathway Commons Protein-Protein Interactions	1.0	null
RARRES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8231
PSMD1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K10087503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01935
AB-33-EM56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.22075
BRD-K15087476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19781
BRD-K06094529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33365
BRD-K06174863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.35128
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.1751
ERLIN2	Pathway Commons Protein-Protein Interactions	1.0	null
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.1
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3RD-01A-12R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRN-0011-R5A-SM-2I5EF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09963
GTEX-SN8G-0326-SM-32PLG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
RNA recognition motif domain	InterPro Predicted Protein Domain Annotations	1.0	null
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K45904718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.38747
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.8544
NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6778
Vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.6061
Pollen coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.872
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.143
PMC12069319-Table1.xlsx-OCAB_WT_BirA-Gene_Symbol_POU2AF1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94795
HDAC2	ENCODE Transcription Factor Targets	1.0	null
Spliceosomal snRNP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.143
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-3_E2F2-Gene_E2F2	Rummagene Transcription Factor Associations 2026	1.0	null
RALYL	Pathway Commons Protein-Protein Interactions	1.0	null
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.991315
Brain Lower Grade Glioma_LGG_TCGA-DU-6397-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
brain	GTEx Tissue Gene Expression Profiles	1.0	1.73914
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	71.0591
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.941882
hsa-miR-3117-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.9384
Muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.82
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-QEL4-0926-SM-3GAD1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
COLO 205	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.84007
Lung squamous cell carcinoma_LUSC_TCGA-21-1080-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K80196706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02543
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.5635
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RPL17	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-WFON-2326-SM-3LK7M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
MDAMB175VII	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.945559
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.41921
MED12	Pathway Commons Protein-Protein Interactions	1.0	null
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Sarcoma_SARC_TCGA-X6-A8C4-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P44H-0011-R5A-SM-2XCEX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05866
GTEX-PLZ4-0226-SM-2S1NW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
MGMT	Pathway Commons Protein-Protein Interactions	1.0	null
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.76786
Ophthalmoplegia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.395
Prostate adenocarcinoma_PRAD_TCGA-YL-A8S9-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TNIP3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00623595
H3K9ac_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.999091
GTEX-PX3G-1426-SM-48U1J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
ENTPD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0078298
RNA cap binding complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.852
GTEX-X4EO-0526-SM-3P5Z3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
SKM1	CCLE Cell Line Gene Expression Profiles	1.0	1.87752
EIF4A1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K19817946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1507
cytoplasm	LOCATE Curated Protein Localization Annotations	1.0	null
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.88598
PRKCD	Pathway Commons Protein-Protein Interactions	1.0	null
MSH2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TEF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4505
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6353
PPP1CC	Pathway Commons Protein-Protein Interactions	1.0	null
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.3405
NCVADR RES	BioGPS Cell Line Gene Expression Profiles	1.0	1.20648
RNASEL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00396864
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.18447
cellular macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5L8-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS766T	CCLE Cell Line Gene Expression Profiles	-1.0	-3.99891
Nucleotide-binding alpha-beta plait domain	InterPro Predicted Protein Domain Annotations	1.0	null
SW1990	DepMap CRISPR Gene Dependency	1.0	3.64003
GTEX-POMQ-0126-SM-48TD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-S95S-0226-SM-4B656	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
YWHAG	Pathway Commons Protein-Protein Interactions	1.0	null
synapse-associated extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.758
EP300	ENCODE Transcription Factor Targets	1.0	null
VCP	Pathway Commons Protein-Protein Interactions	1.0	null
Ovarian cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.037
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
a431	HPA Cell Line Gene Expression Profiles	1.0	1.17434
BL3173 (MAVS)	NURSA Protein Complexes	1.0	null
GTEX-XPT6-1626-SM-4B655	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50736
SNRPA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00908371
EIF3B	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-4652-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Perinucleolar compartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.593
GTEX-NPJ8-0326-SM-2D7VV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
mRNA binding	GO Molecular Function Annotations 2025	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.915253
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE240386,GSE242143_1_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
DHX36	Pathway Commons Protein-Protein Interactions	1.0	null
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.42817
BRD-K02602127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4227
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.58958
SNRNP200	Pathway Commons Protein-Protein Interactions	1.0	null
H9 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.48299
BRD-K83751422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41279
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
fusiform gyrus, right, bank of cos	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.75679
Perineuronal net	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.763
YBX1	Pathway Commons Protein-Protein Interactions	1.0	null
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9219
BRD-K26091803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60938
midbrain raphe nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.46874
CARS	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ATP2B2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-NL3H-0011-R5a-SM-2I3GB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832346
GTEX-U4B1-1626-SM-3DB8N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.934048
GTEX-WHPG-1426-SM-3NMBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BRD-K11812419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41053
BRD-K10148216	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57748
H3K27me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Male infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.017
TCP1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RPL28	Pathway Commons Protein-Protein Interactions	1.0	null
PMC3644282-1471-2164-14-110-S3.xls-Contextual_Gene_Set_TCGA-GBM-OVOL2_OVOL2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A69Q-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HS 766T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-3.23449
single-stranded DNA-binding protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.866
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2501
Translation release factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.521
BRD-K59437706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06841
tonsil	HPA Tissue Protein Expression Profiles	1.0	0.894549
CBX2	ENCODE Transcription Factor Targets	1.0	null
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HNRNPH2	Pathway Commons Protein-Protein Interactions	1.0	null
HNRNPA1	Pathway Commons Protein-Protein Interactions	1.0	null
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
doxorubicin_homo sapiens_gpl96_gds3514	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.07411
Transcription export complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.925
DDX3X	Pathway Commons Protein-Protein Interactions	1.0	null
Bloodstream form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.065
ABC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.825698
BRD-K27885839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73434
HNRNPM	Pathway Commons Protein-Protein Interactions	1.0	null
COLO678	CCLE Cell Line Gene CNV Profiles	1.0	1.61172
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.80843
Lung squamous cell carcinoma_LUSC_TCGA-O2-A52W-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Non-Obstructive Azoospermia	DisGeNET Gene-Disease Associations	1.0	null
BRD-K33454318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.23601
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Decreased_in_both_CSDE1_KD_hESC-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XPVG-0008-SM-4GICH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07649
Mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
primary motor cortex (area M1, area 4)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20708
CLCF1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Box C/D RNP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.89
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3J4-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sclerenchyma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.502
BRD-K43798660	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.7775
CRCGN015_MCF10A_48H:I06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24055
GTEX-PLZ6-0326-SM-3P61J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BV-173	GDSC Cell Line Gene Expression Profiles	1.0	1.84142
heterocycle metabolic process	GO Biological Process Annotations 2015	1.0	null
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-0.99651
BRD-A29578214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4404
BRD-K60531990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05923
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.963833
H3K27me3_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K09108485	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02101
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.195
GTEX-O5YT-0926-SM-48TDG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-gene_id_y_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
heart_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.03591
H3K9me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.2544
NCIH522	CCLE Cell Line Gene Expression Profiles	-1.0	-2.2313
molecular_function	GO Molecular Function Annotations 2015	1.0	null
BRD-K59544784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4519
Oculopharyngeal muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.915
BRD-K31503053	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77704
heart muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.2567
CEM-VBL100 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.784
Prostate adenocarcinoma_PRAD_TCGA-FC-A4JI-01A-11R-A250-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KCNAB1	Pathway Commons Protein-Protein Interactions	1.0	null
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.2928
BRD-K42191735_buparlisib_MCF7_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3NA-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5098-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.0001
hippocampus (hippocampal formation)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01777
CCDC106	Pathway Commons Protein-Protein Interactions	1.0	null
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.965084
FBL	Pathway Commons Protein-Protein Interactions	1.0	null
CLGN	Pathway Commons Protein-Protein Interactions	1.0	null
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.9644
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.898054
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context1_2-Nearest_Ensembl_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
MRPS5	Pathway Commons Protein-Protein Interactions	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TW-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTSB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00423608
NCI-H1155	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.862579
EDC4	Pathway Commons Protein-Protein Interactions	1.0	null
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
22RV1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K21466747	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24581
GTEX-O5YT-1826-SM-32PK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
COPG1	Pathway Commons Protein-Protein Interactions	1.0	null
Exoneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.583
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.76786
posteroventral (inferior) parietal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.992444
MYO1F	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0062524
KARS	Pathway Commons Protein-Protein Interactions	1.0	null
MM1S	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.19608
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18139
PMC7455079-jciinsight-5-140380-s227.xlsx-Supp_Table_9-Supplemental_Table_9_Limma_DE_Analysis_of_HC_AA_to_EA_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A6UG-01A-32R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lung	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
poly(A) binding	GO Molecular Function Annotations 2023	1.0	null
GSK3B_KD_GDS4305_183_human_THP-1 acute myeloid leukemia cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-OHPL-1826-SM-2YUN8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
105KC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09542
FBXO7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00465924
Brain Lower Grade Glioma_LGG_TCGA-E1-5304-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CNOT10	Pathway Commons Protein-Protein Interactions	1.0	null
RCSD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00523496
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_3H:G08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.10981
MED23	Pathway Commons Protein-Protein Interactions	1.0	null
SU-DHL-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06853
RPL10	Pathway Commons Protein-Protein Interactions	1.0	null
famotidine-2029	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A4JJ-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K26233698	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4658
U2 snRNP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.982
BRD-K25649458	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.12538
GTEX-R55G-1126-SM-48FDG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
HSP90AB4P	Pathway Commons Protein-Protein Interactions	1.0	null
ZFR	Pathway Commons Protein-Protein Interactions	1.0	null
TCCSUP	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.33479
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BRD-K67868012_PI-103_HME1_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PLIN3	Pathway Commons Protein-Protein Interactions	1.0	null
HP1BP3	Pathway Commons Protein-Protein Interactions	1.0	null
Rectum adenocarcinoma_READ_TCGA-EF-5830-01A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K23670243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06372
CRCGN008_HEPG2_24H:B14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.70175
CTCF_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2218	GDSC Cell Line Gene Expression Profiles	1.0	1.65459
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A0VL-01A-21R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K18416855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01707
BRD-K66580188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93692
FU97	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCFC1	Pathway Commons Protein-Protein Interactions	1.0	null
sin3a_22783022_mcf7_lof_human_gpl570_gds4388	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.31189
GTEX-QVJO-0011-R4A-SM-2S1QL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949872
MRPS15	Pathway Commons Protein-Protein Interactions	1.0	null
CSDE1	Pathway Commons Protein-Protein Interactions	1.0	null
Ar	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.7301
IKBKG	Pathway Commons Protein-Protein Interactions	1.0	null
MZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01217
AXL	Kinase Library Tyrosine Kinome Atlas	1.0	97.68
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.917344
Anterior midgut	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.97
BICD1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K37696710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74643
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19437
BRD-K44416503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56992
U251	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.0273
GTEX-NL4W-0011-R2a-SM-2I5GV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939649
cisplatin_homo sapiens_gpl570_gse23553	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-VJYA-0426-SM-3GIJK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BRD-K77060313	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85014
esophagus	HPA Tissue Protein Expression Profiles	1.0	1.32548
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.62419
PRMT5	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RU1J-1026-SM-46MUR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
OLA1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K46313713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06603
TRIM28	Pathway Commons Protein-Protein Interactions	1.0	null
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.65551
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RNA metabolic process	GO Biological Process Annotations 2025	1.0	null
RPL14	Pathway Commons Protein-Protein Interactions	1.0	null
CBX8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10041
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.909941
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77704
LATS1	Kinase Library Serine Threonine Kinome Atlas	1.0	null
Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.038
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4698-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-5303-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RIGI	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0057031
MOV10	Pathway Commons Protein-Protein Interactions	1.0	null
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15491
GTEX-S341-2026-SM-2XCAA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
H3K27me3_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YJ-A8SW-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dcp1-Dcp2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.778
CRCGN011_HEPG2_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13765
PMC7880998-41467_2021_21255_MOESM8_ESM.xlsx-Sup_Data_5_TWIST_Panel-Gene_Name_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K47175449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27626
COLO201	CCLE Cell Line Gene CNV Profiles	1.0	1.42445
GTEX-QDT8-0011-R1A-SM-32PKS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1053
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	2.45089
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.970896
MCM6	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Extracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Intracranial aneurysm	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.61549
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.08165
AU565	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.28029
GTEX-T5JC-2126-SM-32PMO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
TEX10	Pathway Commons Protein-Protein Interactions	1.0	null
THRAP3	Pathway Commons Protein-Protein Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A729-06A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WYVS-2326-SM-3NMAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
RPL37A	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QDVJ-1926-SM-2S1PJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
outer CP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.855272
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Change_in_both_CSDE1_KD_hESCs-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.30366
SOBP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00649734
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.3624
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
FGA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00589517
BRD-K26282994	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35024
ELMO2	Pathway Commons Protein-Protein Interactions	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78O-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.WT.HP_24H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.4048
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0706
CRCGN015_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.97085
respiratory system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
NCI-H2803	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.915016
RTCB	Pathway Commons Protein-Protein Interactions	1.0	null
EIF4A2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
stratum radiatum of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19658
BRD-K56408846	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3692
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.584
GTEX-QCQG-1926-SM-2S1PI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
UQCRC2	Pathway Commons Protein-Protein Interactions	1.0	null
TRAP1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-SUCS-0926-SM-4DM4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BRD-K61168987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57332
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74813
BRD-K30055322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.82291
L428	CCLE Cell Line Gene Expression Profiles	1.0	1.4589
RCH-ACV	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MRPL45	Pathway Commons Protein-Protein Interactions	1.0	null
CA2 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.9174
GTEX-R55D-0926-SM-3GAEU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
S100A8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00440744
poly(a) binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K83846772	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47927
Female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-VUSG-2226-SM-4KKZO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41606
RNF2	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4770-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
EIF3D	Pathway Commons Protein-Protein Interactions	1.0	null
PRRC2C	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OIZI-0126-SM-3NB13	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5318
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
TK10	BioGPS Cell Line Gene Expression Profiles	1.0	0.869769
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7II-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HSP90AA2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QESD-0626-SM-2I5G4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41781
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55716
outer CP in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.940362
GTEX-RVPU-0011-R3A-SM-2XCAE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877708
SU-DHL-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.31951
RPS6	Pathway Commons Protein-Protein Interactions	1.0	null
HNRNPR	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-N7MT-0011-R4a-SM-2I3G9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865937
ACTN3	Pathway Commons Protein-Protein Interactions	1.0	null
testis	GeneRIF Biological Term Annotations	1.0	null
GSE236502_2_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
SUPHD1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39718
HNRNPA0	Pathway Commons Protein-Protein Interactions	1.0	null
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.974003
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.1161
BL2368 (KIAA0528)	NURSA Protein Complexes	1.0	null
GTEX-QMR6-0011-R7A-SM-32PKL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3582
DNAL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17391
BL5638 (AKAP13)	NURSA Protein Complexes	1.0	null
GTEX-PWCY-0526-SM-2I3ER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Methionine adenosyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.72
GTEX-PVOW-0008-SM-48TE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
496100306_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.3465
HR	Pathway Commons Protein-Protein Interactions	1.0	null
GNL2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BRD-K04771555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27569
GNL3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K64215924	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62034
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4389
GTEX-TML8-1826-SM-32QOR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10361
SF3B1	Pathway Commons Protein-Protein Interactions	1.0	null
Right_Atrium	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.3496
GTEX-WH7G-1626-SM-4LVMY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
XRCC6	Pathway Commons Protein-Protein Interactions	1.0	null
Female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K18978449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08535
GTEX-QESD-1526-SM-2S1QT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07887
KLC1	Pathway Commons Protein-Protein Interactions	1.0	null
NONO	Pathway Commons Protein-Protein Interactions	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A4BA-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.049
GTEX-X4XY-0526-SM-46MW1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
PLS3	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H2196	GDSC Cell Line Gene Expression Profiles	-1.0	-2.09562
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AG-2926-SM-2HMJ3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990762
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.25634
GTEX-UPIC-1426-SM-4IHLQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
RNF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEG5-0326-SM-2S1PB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89419
TUBB1	Pathway Commons Protein-Protein Interactions	1.0	null
496100462_PCx_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.37932
BRD-K54463500	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41759
BRD-K86537726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2312
GTEX-N7MS-0011-R5a-SM-2HMK8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850501
BRD-K62369921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34067
inferior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.28323
GTEX-P78B-1126-SM-3P615	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
MRPL3	Pathway Commons Protein-Protein Interactions	1.0	null
HSPA9	Pathway Commons Protein-Protein Interactions	1.0	null
HS 766T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.97285
FHL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00513082
ETNK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00562374
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K20951097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01769
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
VARS	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K91818277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66454
BRD-K97537859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1845
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88955
PMC3348545-NIHMS263168-supplement-3.pdf-284-VENTX_VENTX	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22481
ESYT1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-T2IS-2626-SM-32QPP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
PELP1	Pathway Commons Protein-Protein Interactions	1.0	null
CL-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40674
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HL60	CCLE Cell Line Gene Expression Profiles	1.0	1.56836
CBX2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.932342
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.950594
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6793-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DBTRG-05MG	GDSC Cell Line Gene Expression Profiles	-1.0	-1.45493
HCC2935	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61552
AGPAT5	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K62841603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22373
CD4_Naive_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.28458
H3K4me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05935
RPL13	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K00530465	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53179
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
PTPN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0065234
LB831-BLC	GDSC Cell Line Gene Expression Profiles	-1.0	-1.66989
H3K9me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
FMR1	Pathway Commons Protein-Protein Interactions	1.0	null
VANGL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00570231
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Lung adenocarcinoma_LUAD_TCGA-78-7154-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.876151
Translation repressor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.027
BRD-K63665694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40032
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A68F-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
F5 meningioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.552
GNA13	Pathway Commons Protein-Protein Interactions	1.0	null
APOBEC3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00741513
L-363	GDSC Cell Line Gene Expression Profiles	1.0	1.59907
GTEX-UJMC-1926-SM-3GADS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
sodium-phenylacetate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7642
CL-40	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22933
SNU1196	DepMap CRISPR Gene Dependency	1.0	4.08778
M14	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.912526
GTEX-XUZC-2026-SM-4BRW9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
ITCH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00661271
ELF1	ENCODE Transcription Factor Targets	1.0	null
HCC1806	CCLE Cell Line Gene CNV Profiles	-1.0	-1.84099
HUH6	CCLE Cell Line Gene Expression Profiles	1.0	1.68447
RAMP3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00675381
GTEX-T6MN-0926-SM-32PLX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.302
BRD-K19231873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52786
CRCGN015_MCF10A_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.05089
Polyadenylate-binding protein/Hyperplastic disc protein	InterPro Predicted Protein Domain Annotations	1.0	null
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-452	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
ATXN10	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
BL6410 (BCOR)	NURSA Protein Complexes	1.0	null
DNM3	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QDT8-0011-R6A-SM-32PKI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15473
male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
CRCGN017_MCF10A.WT.HP_24H:G18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22055
NCIH441	DepMap CRISPR Gene Dependency	1.0	2.78359
GTEX-SIU7-1626-SM-4BRUK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
COLO205	CCLE Cell Line Gene CNV Profiles	1.0	2.26306
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.9049
GTEX-TKQ1-1026-SM-4GICL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961324
ATAD3B	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K13551202	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5465
PPA2	Pathway Commons Protein-Protein Interactions	1.0	null
LARP1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K69491845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26497
vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
DHCR7	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K34929471	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.11518
SK-N-FI	GDSC Cell Line Gene Expression Profiles	-1.0	-1.65994
nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
MEF2A	JASPAR Predicted Transcription Factor Targets	1.0	null
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Lung squamous cell carcinoma_LUSC_TCGA-77-8007-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H748	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.82108
GTEX-QMR6-0011-R1A-SM-32PKW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00857
BRD-K16551475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07017
LU-135	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.914119
SRPR	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RU72-0226-SM-46MUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
KTN1	Pathway Commons Protein-Protein Interactions	1.0	null
MED14	Pathway Commons Protein-Protein Interactions	1.0	null
ERA-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC12956708-DataSheet1.xlsx-Supplementary_Table_7-Supplementary_Table_6_The_DEGs_from_high_altitude_between_AMS_and_non-eAMS_group_of_GSE75665_TWIST2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QVUS-2926-SM-3GIJB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.979559
GSE166783_8_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68403
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.870739
BRD-K72717797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43944
DNTTIP1	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5525-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BRD-K89668690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00744
L-428	GDSC Cell Line Gene Expression Profiles	1.0	1.78137
BRD-K38273665	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33546
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K59049340	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16183
BRD-K38258132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59089
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
NXPH4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00741605
CRCGN015_MCF10A_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.59897
Malignant mesothelioma of pleura_Pleura_GSE2549	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.85703
SLC25A5	Pathway Commons Protein-Protein Interactions	1.0	null
Sarcoma_SARC_TCGA-DX-AB2X-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.84135
XRCC4	Pathway Commons Protein-Protein Interactions	1.0	null
pedunculo(pontine) tegmental  nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12116
HEY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.840484
BRD-K53774864	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17784
WWOX	Pathway Commons Protein-Protein Interactions	1.0	null
CHCHD2	Pathway Commons Protein-Protein Interactions	1.0	null
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.837883
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KHSRP	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K23585987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55707
GTEX-RTLS-2626-SM-46MUJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
HCC2218	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41606
GTEX-XUW1-2326-SM-4BOO5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-U412-0426-SM-3DB9O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.40621
GTEX-R55E-0011-R5A-SM-2TC5N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92582
HEATR4	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K61168922	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33793
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K10494344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44712
LCLC103H	DepMap CRISPR Gene Dependency	1.0	5.36319
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
NCIH2227	CCLE Cell Line Gene Expression Profiles	-1.0	-1.66427
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWO3-0011-R1A-SM-2I5EW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20631
SK-N-SH	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.959734
PSMD11	Pathway Commons Protein-Protein Interactions	1.0	null
HDAC2	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.97317
THO complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.978
salivarygland_6b	HPA Tissue Sample Gene Expression Profiles	1.0	0.967773
BRD-K51697562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27401
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.3993
KLE	CCLE Cell Line Gene CNV Profiles	-1.0	-2.41434
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.25883
poly-pyrimidine tract binding	GO Molecular Function Annotations 2025	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A7M4-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYO1C	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN008_HEPG2_24H:I08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.15025
tamoxifen_homo sapiens_gpl96_gds2367	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TWISTNB	Pathway Commons Protein-Protein Interactions	1.0	null
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.189
MZ in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.48781
CRCGN017_MCF10A.WT.HP_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.70305
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ARHGAP18	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00512376
PMC8040704-jcav12p2673s2.xlsx-Up-regulated_genes_in_EBF1-Unnamed_5_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
ARHGAP27	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0052014
CLNK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0049662
TMEM255A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00560891
Eukaryotic translation initiation factor 2B complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.102
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE183101_0_v_1_hvcn1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MRPS2	Pathway Commons Protein-Protein Interactions	1.0	null
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-1n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
496100392_HIP_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.20371
SNU308	CCLE Cell Line Gene Expression Profiles	-1.0	-2.00799
TARS	Pathway Commons Protein-Protein Interactions	1.0	null
MRPS21	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K00234327_RU 24969_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
15208663-SuppTable1a	GeneSigDB Published Gene Signatures	1.0	null
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46014
CLIC1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-R53T-0926-SM-3GADH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	83.6838
PMC7415402-oncotarget-11-2995-s004.xlsx-EWS-FLI1_Type_1_vs_Type_3-Gene_Symbol_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K78196882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41226
ARPC5L	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPP2R1A	Pathway Commons Protein-Protein Interactions	1.0	null
SC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.22249
ACE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00632074
H3K9me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K82198647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-6.22777
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-R45C-1226-SM-48FEE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
GTEX-O5YW-0126-SM-3LK6D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BRD-K64264263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4778
GTEX-RM2N-1826-SM-2TF5B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
MV-4-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.80641
PMC10123531-NIHMS1874945-supplement-Table_S6.xlsx-SOX2_BCAT_cobound_peaks-Gene_Name_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K60807536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4303
RPL23A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00960644
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DYNLL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00484794
CHD1	ENCODE Transcription Factor Targets	1.0	null
HNF4, COUP	MotifMap Predicted Transcription Factor Targets	1.0	null
RRP12	Pathway Commons Protein-Protein Interactions	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
Rectum adenocarcinoma_READ_TCGA-CL-5918-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A50E-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBE3C	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IK-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIGLEC6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00550072
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.7678
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20039
GTEX-O5YV-2026-SM-2D7VS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
hsa-miR-149-5p	MiRTarBase microRNA Targets	1.0	null
SMARCA4-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
mRNA 3'-UTR binding	GO Molecular Function Annotations 2025	1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-SJXC-0526-SM-2XCFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.27
BL1575 (CDC2L6)	NURSA Protein Complexes	1.0	null
Messenger ribonucleoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.494
CHUK	Pathway Commons Protein-Protein Interactions	1.0	null
internal female genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
MYC	ENCODE Transcription Factor Targets	1.0	null
GSE76425_0_v_5_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:N23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06095
CI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.989558
GEMIN4	Pathway Commons Protein-Protein Interactions	1.0	null
dizocilpine-1386	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-94-A5I4-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.137
YD-49-HM53_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.268068
liver	GTEx Tissue Gene Expression Profiles	-1.0	-1.48883
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5466-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31345
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.900034
AF-41-QY60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.24893
GIGYF1	Pathway Commons Protein-Protein Interactions	1.0	null
D-247MG	GDSC Cell Line Gene Expression Profiles	-1.0	-1.85112
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.939223
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TGBC24TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
E2F4	ChEA Transcription Factor Targets	1.0	null
MCM4	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WL46-0626-SM-3LK7R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.825081
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ES-WA7 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.17245
UBB	Pathway Commons Protein-Protein Interactions	1.0	null
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.2985
ARPC2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WFG8-1326-SM-4LVN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Cytosolic ribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.642
EIF4A3	Pathway Commons Protein-Protein Interactions	1.0	null
CYP24A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00864629
KO52	CCLE Cell Line Gene CNV Profiles	1.0	1.96803
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8098-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BICR 22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20039
hsa-miR-590-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
BRD-K55399138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27756
GTEX-OOBJ-0226-SM-2YUMM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.94813
COQ2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00506807
LN235	CCLE Cell Line Gene Expression Profiles	-1.0	-1.75209
GTEX-WQUQ-1426-SM-3MJFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
ELAVL1	Pathway Commons Protein-Protein Interactions	1.0	null
HELF cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.549
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3998
CRCGN008_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4151
MYO1F	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-R53T-1326-SM-48FCQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Prostate adenocarcinoma_PRAD_TCGA-KK-A8ID-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.798
GTEX-S32W-0126-SM-4AD61	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
APEH	Pathway Commons Protein-Protein Interactions	1.0	null
NCAPG	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4354-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.224
GTEX-XOT4-1126-SM-4B66E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
MYLK2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79084
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.66109
BRD-K71059170_Cefixime_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
urinary bladder	HPA Tissue Protein Expression Profiles	1.0	1.32548
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K93335719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23481
CRCGN016_MCF10A.TP53.M_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.7445
DDX5	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K48863591	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65968
hsa-miR-3145-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1033
CUL4B	Pathway Commons Protein-Protein Interactions	1.0	null
PHB2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K97741413	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30313
KURAMOCHI	COSMIC Cell Line Gene CNV Profiles	1.0	2.76305
SMTN	Pathway Commons Protein-Protein Interactions	1.0	null
CYSLTR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00573795
GSS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00533362
MCM2	Pathway Commons Protein-Protein Interactions	1.0	null
CKAP4	Pathway Commons Protein-Protein Interactions	1.0	null
testis_7e	HPA Tissue Sample Gene Expression Profiles	1.0	1.94136
BRD-K40894545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07662
TLR9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00658061
Follicular thyroid cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.693
GNB3	Pathway Commons Protein-Protein Interactions	1.0	null
UPCISCC152	DepMap CRISPR Gene Dependency	1.0	2.29403
P granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.645
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7PM-0011-R5A-SM-3NM8G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94715
extracellular vesicular exosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.837446
GTEX-OOBK-1626-SM-2HMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
SPTBN1	Pathway Commons Protein-Protein Interactions	1.0	null
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2166
BPH1	DepMap CRISPR Gene Dependency	1.0	8.76835
EEF1D	Pathway Commons Protein-Protein Interactions	1.0	null
T84	DepMap CRISPR Gene Dependency	1.0	8.39323
Procyclic form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.16
SFPQ	Pathway Commons Protein-Protein Interactions	1.0	null
CYFIP1	Pathway Commons Protein-Protein Interactions	1.0	null
CD8_Naive_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.26753
Prostate adenocarcinoma_PRAD_TCGA-HC-A4ZV-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H508	COSMIC Cell Line Gene CNV Profiles	1.0	2.76305
PKM	Pathway Commons Protein-Protein Interactions	1.0	null
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.3203
CTCF-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ESYT2	Pathway Commons Protein-Protein Interactions	1.0	null
CYRIA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00578655
GTEX-OXRL-0526-SM-2I3EZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
layer V of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.65486
GTEX-RN64-2326-SM-48FDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6641
SMAD4-19686287-HaCaT-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCI-H510A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
precentral gyrus, right, bank of the precentral sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.65783
BRD-K81568980	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73233
SCYL2	Pathway Commons Protein-Protein Interactions	1.0	null
HCC1359	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06265
CRCGN015_MCF10A.WT.HP_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.82332
CTCF_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0226-SM-4B66H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
SUP-B15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.19192
GTEX-QVJO-0011-R9A-SM-2S1QH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969929
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.10971
SLC25A3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-A21524347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39366
BRD-K68635551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88285
Extracellular space	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
HEC-1-B cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.863
GTEX-SJXC-1226-SM-4DM78	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.991202
CRCGN015_HEPG2_48H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.26644
BRD-A71765365_Reserpine_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
YBX3	Pathway Commons Protein-Protein Interactions	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
SLC25A6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00550949
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70P-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K89995901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16373
PBRM1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-SIU8-0826-SM-2XCDQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Kinetoplastid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.211
CRCGN017_MCF10A.WT.HP_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.216
PABPC1	Pathway Commons Protein-Protein Interactions	1.0	null
Pharyngeal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.274
MARS	Pathway Commons Protein-Protein Interactions	1.0	null
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26904
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_InDel-F5-Thygro-r__CIC-1n_h-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
DNAJA2	Pathway Commons Protein-Protein Interactions	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2863-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDC37	Pathway Commons Protein-Protein Interactions	1.0	null
SMARCB1	Pathway Commons Protein-Protein Interactions	1.0	null
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.0569
SCCPDH	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K72519622	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82473
BRD-K07839394	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76695
PK59	CCLE Cell Line Gene CNV Profiles	1.0	1.43649
BRD-K35422614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98491
YT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN015_MCF10A_48H:M19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.26473
Brain Lower Grade Glioma_LGG_TCGA-CS-6666-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2PG-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH2291	CCLE Cell Line Gene CNV Profiles	-1.0	-1.98786
SPC25	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00696169
CYP17A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00661069
POTEKP	Pathway Commons Protein-Protein Interactions	1.0	null
extracellular organelle	GO Cellular Component Annotations 2015	1.0	null
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23249
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K19073426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35748
agranular insular cortex (area Iag)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13907
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K54657536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1526
DDX47	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN015_MCF10A.TP53.M_24H:C04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.08109
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17041
orbital frontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.833722
Cytosolic large ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.234
GTEX-T2IS-0011-R2A-SM-32QPF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997
BRD-K60296400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55816
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09398
BRD-K23503923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27302
PPP2R2A	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K71415389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29916
Prostate adenocarcinoma_PRAD_TCGA-HC-7744-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TKQ2-1726-SM-4DXUP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
BRD-K61868194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11752
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	2.29147
RPLP2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K71607378	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10417
BRD-K66327237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14345
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-4_E2F8-Gene_E2F8	Rummagene Transcription Factor Associations 2026	1.0	null
SUMO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00495558
Lung adenocarcinoma_LUAD_TCGA-49-6761-01A-31R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0816
BRD-K22591777	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24393
Immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.108
SIN3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00689697
primary visual cortex (striate cortex, area V1/17)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.41741
Lung adenocarcinoma_LUAD_TCGA-78-7536-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UPIC-1126-SM-4IHLO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917634
LAD1	Pathway Commons Protein-Protein Interactions	1.0	null
cytoplasm	GO Cellular Component Annotations 2015	1.0	null
PRDX4	Pathway Commons Protein-Protein Interactions	1.0	null