association	dataset	threshold value	standardized value
FANCI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67412
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1441
PITX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24997
FAU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03947
FOXG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45586
Esophagus - Mucosa	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.770108
CDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55352
Superficial temporal artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.963
H3C11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14025
MYBL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66584
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8403
TRIP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26194
DCAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56477
STX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54757
PRKAR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63883
GSE165636_0_v_4_tofacitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF134	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.514
VIPAS39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19601
Intracellular organelle lumen	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
intracellular non-membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
FOXD4L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47183
SMIM26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26787
SIRT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27398
CARD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63588
CENPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27972
RARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3052
Cerebral arterial disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.052
CORO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.68862
GXYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4317
496100384_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.08343
GPATCH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74828
GRHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19679
HLA-DQB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3436
TIMM17B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88712
GSE120612_7_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
modulating	GeneRIF Biological Term Annotations	1.0	null
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE189859,GSE189861_4_v_2_idh1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Nuclear lumen	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
PCNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34011
CYB5R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26839
ZNF692	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.1164
496100303_HIP_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.15588
PMC6187090-mmc1.xlsx-TP53_positive-Symbol_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM234	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.001
PRDM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05036
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.7692
CDC25A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3536
GLIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.1837
FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3405
SOCS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0452
CHEK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88257
TECPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20374
PDK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33929
PTTG1IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98226
NBPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9475
SENP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06297
SP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.913
MCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01003
CNTNAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24681
MGST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5133
KLKB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21075
WRAP73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49276
ELF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9794
HOXA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57349
TFAP2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	133.948
NETO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65427
TIMM8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55384
DPM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65991
ZNF646	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71735
UCHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4165
GSE148200_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
positive regulation of apoptotic process	GO Biological Process Annotations 2025	1.0	null
GAPVD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42448
LRSAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98469
nucleolus	GO Cellular Component Annotations 2023	1.0	null
positive regulation of apoptotic process	GO Biological Process Annotations 2023	1.0	null
IGF2BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12623
SLC16A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6199
NCOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.735
EIF3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06417
INSM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.2083
M6PR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28552
KLF16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56818
PDCD6IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34597
UBE2R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36596
ZIC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.9572
BCAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27404
SLCO4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9602
FURIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3809
ZNF282	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.6464
CAPN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53962
PFDN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11286
GSE130396_8_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNRPD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69454
STAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31408
IL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08707
CLK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69113
DYRK1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48869
MIA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88608
NFKB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.9072
intracellular membraneless organelle	GO Cellular Component Annotations 2025	1.0	null
CCNH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8181
GINM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.453
MEIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4656
RRAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40371
Irregular astigmatism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.09
MED12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1988
RUBCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21524
negative regulation of proteasomal ubiquitin-dependent protein catabolic process	GO Biological Process Annotations 2025	1.0	null
METTL27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07377
RPS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16154
NR2F6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2122
GSE102505_5_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CNOT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64595
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8662
RREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	117.455
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2602
GSE130401_4_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CCDC136	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53744
SCAI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3727
EGR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98549
NRIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94459
SPAST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.85933
MINK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61536
EPPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69618
SUSD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95858
GSE182680,GSE182683_7_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
COL4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30127
GUF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57822
496100553_TCx_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.11902
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
PEX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.18664
gh1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.65
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.7585
CASTOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01382
PMC12339377-41587_2024_2403_MOESM3_ESM.xlsx-TableS6_LPS_screen_GEPs-Unnamed_27_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE202434,GSE202438_15_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GALNT12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54955
Nerve - Tibial	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.869795
SLFN13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71959
NR1H4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61581
NAXD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30545
BIRC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08755
ANP32A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80614
MED28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69324
AFMID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33076
PPP4R3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.69155
HUS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28316
496100368_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.35459
GSE242290_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SRD5A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0587
LATS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05902
ERI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15483
TRAPPC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45967
SYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22533
SIAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6092
ZNF708	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2792
RAD17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2047
TRIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01051
USB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13616
IFT27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02249
UBE2E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80705
DNM1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81683
TERB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19408
GSE214583,GSE214585_1_v_0_steap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PDAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25968
SHPRH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01081
ZNF80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4278
POU2F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.24261
MYH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69273
GSE242290_3_v_2_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RSPRY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65604
CDY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43687
NSUN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38396
ZBTB7B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5958
PIK3C2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1175
INSYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50388
negative regulation of proteasomal ubiquitin-dependent protein catabolic process	GO Biological Process Annotations 2023	1.0	null
MSH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49656
itself	GeneRIF Biological Term Annotations	1.0	null
ASAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74936
ZNF460	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	110.169
membrane-enclosed lumen	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Cestode	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.57
TNRC6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42013
RNF31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09561
ETNK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36251
KIAA0040	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83991
RPRD1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72365
APOE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82522
H4C9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21742
PGAM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7623
SIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2099
PRKAG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34554
NUDT14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33686
NPW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53963
SLITRK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45928
RPL7L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95228
Congenital sucrase-isomaltase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.301
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-MECP2-toNode_MECP2	Rummagene Transcription Factor Associations 2026	1.0	null
ATP6AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64522
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.8353
RABEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46545
negative regulation of proteasomal protein catabolic process	GO Biological Process Annotations 2025	1.0	null
MED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45973
CCNE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05419
FEV	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4492
RAP2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8752
GSE128054_1_v_0_myt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Plasma membrane respirasome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.829
PAX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39549
HIPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56382
RPS24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02775
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8125
CLDN23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6222
MAD2L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.372
ADGRE5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74709
DDA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50723
regulation of proteasomal ubiquitin-dependent protein catabolic process	GO Biological Process Annotations 2025	1.0	null
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	68.2873
ADH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20343
PMS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36604
TMX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70805
WDR35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33564
PDK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63988
TFAP2E	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.551
KLC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73086
NEDD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42472
IZUMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15044
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.061
GSE119978,GSE180930_3_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZBTB7C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5806
LRRC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23599
ARMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19684
negative regulation of ubiquitin-dependent protein catabolic process	GO Biological Process Annotations 2023	1.0	null
ZNF174	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40686
PARL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39556
GSE209911_0_v_1_ncstn_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38398
GSE155031_5_v_3_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
S1PR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81601
FDXR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78136
ZSWIM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46811
GSE142210_3_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Adrenal Gland	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.637193
Organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
TP53I11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14801
WDFY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19007
NarGHI complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.839
GRINA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52737
TMEM263	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88813
PMC7219112__SF7	PFOCR Pathway Figure Associations 2023	1.0	null
GSE215086_0_v_1_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
FBRS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86966
DNM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18047
F8A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9238
POLR2E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32761
GRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41109
RBAK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67965
MON1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0845
TATDN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30294
TMEM88B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75684
FBXL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54806
PDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3675
ZCCHC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6668
SOCS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80192
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2667
CYB5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49036
ETV4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9097
KRIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06462
EXOSC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90188
ITLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.363
RAB41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15397
LSS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25209
HMGCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90213
RMND5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71812
STK36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96753
ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3021
ALDH3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87913
Histone mutated tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.326
C1orf52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51266
TMUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88859
KCNE5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28613
MAFG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21544
CRISPLD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6576
ZNRF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14844
NFIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85895
PARP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55233
IGSF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9006
ZNF101	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58361
SMC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61191
retromer, cargo-selective complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.948
Intracellular non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE189859,GSE189861_0_v_2_idh1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BICDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71548
AMBRA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73803
TAMALIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61568
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3986
ATOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48649
TBC1D10A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66846
NCOA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23256
GTPBP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08683
CYB5R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39232
EXOSC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27937
KCNE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07069
PELI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72011
TRMT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08294
DIXDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55205
ATXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.8703
TOR2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51424
TLE5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99414
Bladder	GTEx Tissue Gene Expression Profiles 2023	1.0	2.85183
TESMIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89093
DYNLT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45842
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.156
SMIM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84562
CBFA2T3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42519
PRR35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4966
RAB1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37325
H3C14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50218
ANKRD28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31679
MAFA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.6748
CLN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61648
GATA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62321
PARD6G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01797
ZNF79	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96694
EPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59907
STARD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61864
Intracellular anatomical structure	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE216043_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nitrate reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.68
COPS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16649
Narcissistic personality disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.705
RPS29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11552
MXI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-5.24138
MRPL24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92579
EEF1E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30046
ABCC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74625
FRS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33941
TRAPPC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04592
GSE202434,GSE202438_7_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27241
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.2369
PNN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44244
SLC29A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44546
KMT2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51715
GYG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51791
ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5554
DNMT3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43085
MAP3K10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28942
PLEKHA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28474
CCDC80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06251
ZNF682	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.0331
Intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
JAK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05473
HADH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25021
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.032
Nucleus	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
STC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43824
IL11RA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52129
LY6G5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17854
RPS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4681
LEFTY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41942
GSE180525,GSE180528_1_v_0_tbx3_human	RummaGEO Gene Perturbation Signatures	1.0	null
SNRNP48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07268
Diffuse midline glioma, H3 K27M-mutant	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.326
SNAP29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05201
PTAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5048
MRPL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19956
PDXP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14575
Esophageal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.142
496100381_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.1334
CCDC127	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0715
TCF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98237
TUBB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15478
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.25743
496100535_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.98216
RASA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94826
Organelle lumen	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GPBP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69428
EML4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3767
CXXC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33635
Syntrophin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.69
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.1588
DPPA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78154
MMRN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40881
PANK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36006
VAT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95525
KCNIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70442
CTCFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7947
POLE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13471
ZNF233	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91112
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.95
SNAI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8817
LDB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11743
CLCN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20837
MDFI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01168
SOGA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66905
GNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99301
LRAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2626
DCAF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.16983
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4786
ZNF22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57274
GSE213715_0_v_1_iqgap2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
OXCT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52027
PMC12358297-41388_2025_3481_MOESM3_ESM.xlsx-S9_ASCL1-regulated_genes-Unnamed_1_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
KIRREL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98426
LRP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.90208
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.428
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7365
UBA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95242
ETV5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4729
ETV5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92534
MTAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37415
HDHD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64611
DUSP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51126
MPST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24559
PNPLA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38109
TMEM25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42161
VPREB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25791
GSE145249_1_v_3_ppm1g_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CEP131	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20703
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_id_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
ASPRV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52734
EIF2B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74606
SETD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34771
RIPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.07254
FARP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43595
MCAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54429
GLI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9487
PGM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84443
Uterus	GTEx Tissue Gene Expression Profiles 2023	1.0	1.30669
NACA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47383
ABCD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35775
TCTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04191
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9442
COA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27302
HAPLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3905
TMEM123	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50588
DPYSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67475
KIF26A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1466
nuclear lumen	GO Cellular Component Annotations 2025	1.0	null
COQ8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31179
positive regulation of programmed cell death	GO Biological Process Annotations 2025	1.0	null
EMC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90726
TENM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24817
GRB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6747
SBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80218
ADPRS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20588
LYRM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.95925
UBE3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2069
KRT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99671
BAG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23826
GSS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43614
VRK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68677
HCFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.14239
RPL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72383
MRPL40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19884
EFEMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81305
KIAA1958	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10464
LSM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15465
TMEM138	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.18894
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.2512
MCM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17309
USP24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02449
mp90	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.362
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0064
NR2C2AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19271
SNX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77501
TNFRSF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41798
RHOA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14024
MAP2K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16679
Tonsil cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.061
GRTP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96362
HDAC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61598
SPINT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27981
PMC8384902-mmc5.xlsx-H128_ASCL1_ChIP-Symbol_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
TDRD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03819
DMTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97516
COL16A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72263
NOL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.9248
EEIG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86131
TMEM69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57438
Cambium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.722
TCF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46843
Htk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.972
MUC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33433
KIF1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63705
ZNF550	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45767
CENPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15437
GMFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33041
CCDC92B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50248
DCHS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45654
FAM76B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57997
regulation of proteasomal ubiquitin-dependent protein catabolic process	GO Biological Process Annotations 2023	1.0	null
AP5B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41416
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2192
PAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23902
APRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64889
LHX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57866
MSANTD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89872
PMC10247733-41408_2023_863_MOESM4_ESM.pdf-574-ZSCAN1_ZSCAN1	Rummagene Transcription Factor Associations 2026	1.0	null
ATP6V0B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54774
Adenoid cystic carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.073
496100507_FWM_dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07436
EDEM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41872
DCAF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47879
ZBTB24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.4372
Intracranial arterial disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
SLC9A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04249
TSPAN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18793
ZKSCAN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.6286
VPS18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47307
TUBB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17893
GSE121198,GSE129779_0_v_2_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
AAAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9856
Corneal ectasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.1
ABTB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98082
B3GALNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6344
496100363_TCx_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.32517
PPM1H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10205
ZBTB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35796
TRUB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.44171
ANAPC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15227
PMC7219112__F7	PFOCR Pathway Figure Associations 2024	1.0	null
Esophageal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.157
RPL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65988
GSE195663_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PRPF39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9343
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3073
KLHDC8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55611
RMI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40293
METTL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46115
Breast - Mammary Tissue	GTEx Tissue Gene Expression Profiles 2023	1.0	2.55277
CLPSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58085
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3424
GA-88-CF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.24566
CCDC90B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77832
ZEB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05939
SKIDA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02125
WDR44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62421
CDK2AP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52416
NCOA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25135
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.52904
ZNF449	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8214
GPR180	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52707
RPUSD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13238
AARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50495
MAP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9373
DCAF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76784
FAM193B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34856
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6637
MED6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42717
ACSM2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66404
MPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54159
MED24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95572
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8519
ESR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.5604
SEC23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34472
EVA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85231
GPRC5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.406
regulation of apoptotic process	GO Biological Process Annotations 2025	1.0	null
DHX38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31003
GORASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52919
RAB32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53096
TWIST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.26453
PRXL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79012
DKC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59476
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.3089
MTMR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.78905
PAS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.901
ENTPD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46569
DLGAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2907
CYRIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47388
PTPRCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33445
CHCHD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92305
RAPGEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77738
IRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32469
C10orf88	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23445
GSE106661,GSE106665_2_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
positive regulation of programmed cell death	GO Biological Process Annotations 2023	1.0	null
DPEP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63158
NTMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62806
ATXN7L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.91451
METTL25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38691
ZNF549	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.2983
SMURF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79293
LRRC34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56517
B4GALT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70371
DA-46-KH36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.241559
GART	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32471
GBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92675
RAB15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17886
Intracranial aneurysm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.109
TRIB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10702
GPX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83119
non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
DRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24981
negative regulation of proteasomal protein catabolic process	GO Biological Process Annotations 2023	1.0	null
NPHP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.764
SEC14L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83054
Plant candle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.883
CD200	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55404
ILKAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43402
ZNF681	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17998
HSD17B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56283
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3971
MG-63 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.876
NUP42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60729
MRPL52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06382
ATP13A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55045
GSE196505,GSE196507_1_v_2_kdm2b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
APOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3275
AMOTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17901
ACTR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27473
VEZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.1034
SUN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19222
H4C3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27793
WIPI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67623
RNF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28894
SMARCE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40559
GSE205163,GSE205164_3_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MROH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87035
ADAMTS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02277
ASB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5895
TRMT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49529
CWC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45534
SLC52A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49491
DPH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39635
EMC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01599
Mo-B cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.593
suppressor	GeneRIF Biological Term Annotations	1.0	null
LRRC75A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42719
PHACTR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29683
496100374_HIP_possible Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.03064
RUNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53543
Brain - Hypothalamus	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.869795
UBE3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79864
CBX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55118
Cysteine synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.917
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3977
C4orf36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.65416
POU6F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18139
NEFH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32815
496100359_PCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.11807
H1-4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71636
SLC37A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34555
CDC23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33626
NYAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.46866
DBNDD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.31585
SLC15A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54836
RASSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15223
TMEM169	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88272
GSE168918_1_v_0_tmprss4_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34029
CCND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42573
GCM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2558
TEAD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8169
RPP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13955
Intraciliary transport particle A	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.647
JMJD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15725
GSE133927_1_v_0_meox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SPATA20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96548
MRPS25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26179
Lung	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.670422
NMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23488
NFKB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.7704
KLF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39355
496100450_HIP_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.10925
MX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10214
GSE230573_1_v_0_dcaf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RNF130	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19453
GSE148200_0_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cellular anatomical entity	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
CD68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95111
NTF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69082
DHX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89795
candidate	GeneRIF Biological Term Annotations	1.0	null
SNX11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01536
RAPGEFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52986
ZSWIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41537
UBXN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9156
negative regulation of ubiquitin-dependent protein catabolic process	GO Biological Process Annotations 2025	1.0	null
PGAM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98235
SCN5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42733
SLC10A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24207
Schnyder corneal dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.24
496100531_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.23666
RBM26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54489
KLLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.617
GSE118939_1_v_0_nras_human	RummaGEO Gene Perturbation Signatures	1.0	null
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3094
SEPTIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94948
KLHDC7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63323
FLNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40881
PMM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2574
apoptosisinducing	GeneRIF Biological Term Annotations	1.0	null
GINS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83189
Cells - EBV-transformed lymphocytes	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.903023
UPF3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86941
MRPL54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48579
GSE139455_4_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RABGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90801
PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-DMOG_-_HIF1A-gene_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
EZR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76977
mp88	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.359
Cul2-RING ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.755
496100349_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.82906
CCT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91454
GPR50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73701
HRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09939
TMOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11651
OE-21 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.896
ZNF707	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.3319
IQGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53631
TTI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3255
UBFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68864
FBLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64254
regulation of apoptotic process	GO Biological Process Annotations 2023	1.0	null
MRPL19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11983
UBE2V2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34589
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_name_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF256	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54893
496100611_FWM_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.22425
496100549_FWM_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.17124
CUL4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.36653
FABP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72533
DNAJB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60007
nucleolus	GO Cellular Component Annotations 2025	1.0	null
AIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97073
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.336851
FBXW4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43182
ASAP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.729
INTS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20359
ZNF146	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23078
NDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47326
TRIM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03299
496100354_PCx_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.43231
BRINP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23236
XRCC2-RAD51D complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.613
CPNE9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60217
EDRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84817
MAPK11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16568
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8845
ACADVL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13444
BRME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57963
PTPRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41946
Sarcoglycan complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.674
TFAP2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35669
HIVEP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28912
LHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29919
nuclear lumen	GO Cellular Component Annotations 2023	1.0	null
CCZ1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68438
Cells - Cultured fibroblasts	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.869795
GSE130396_1_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAPK8IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90122
SP140L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11123
PELO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31859
CCDC96	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.31592
TMEM59L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54809
ZNF740	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	133.841
PPP1R1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19082
RAC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24311
ATP8B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61696
496100355_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.11349
ANKRD13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.59421
496100351_FWM_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.2862
AGAP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57787
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
ITPRIPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07869
ERF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4618
PCDHB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91975
PLS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35146
KDM3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32211
HDLBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08907
NOTCH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61052
Nucleolus	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
NPAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21727
MDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24321
GLIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4813
COX20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64307
RAB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26475
TMX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61743
CCDC97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19469
RPUSD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16092
CRYGD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59063
TUBA4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4928
RAB21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83252
TRIM26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29411
SOX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21095
RPS6KL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08454
ENDOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1668
p14arf	GeneRIF Biological Term Annotations	1.0	null
TMEM167B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50386
TMEM265	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58542
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.913
NFYC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22722
GNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51573
TP53BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36172
FNDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88077
EFS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72004
ZNF493	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25557
MAZ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	76.2276
HPS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7006
UTP14C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49516
AURKAIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94974
COX11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29694
DNAJC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31027
PMC12178829-mmc4.xlsx-Sheet_4-MEG3-KD_Up-GeneName_AR	Rummagene Transcription Factor Associations 2026	1.0	null
FIZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.94017
ZNF346	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28624
TMEM106A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2217
Fc-epsilon receptor I complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.731
CC2D1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55872
QTRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37625