association	dataset	threshold value	standardized value
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AG-0008-SM-48U2K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.934134
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	55.3374
GSE110178_2_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
suppressor	GeneRIF Biological Term Annotations	1.0	null
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2273
MONOMAC1	CCLE Cell Line Gene Expression Profiles	1.0	1.76582
Lung adenocarcinoma_LUAD_TCGA-86-8671-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIX5_02_78	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.58496
primary auditory cortex (core)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3863
REEP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60204
GSE154767_4_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19998
PMC12500496-262_2025_4178_MOESM2_ESM.xlsx-THP1_enriched_for_CVGBM-gene_name_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
KLHL42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82821
PMC8905236-mmc2.xlsx-Table_S10-Table_S10_Differentially_regulated_genes_in_SPI1_high_vs_low_group_in_CGGA_GBM_dataset_SPI1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DE-98-FC24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.393025
superficial stratum of r3BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14695
GSE215086_0_v_1_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.891279
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64383
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840291
GTEX-RN64-0326-SM-2TC5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.982157
MELHO	CCLE Cell Line Gene CNV Profiles	1.0	2.42576
ATF2	ENCODE Transcription Factor Targets	1.0	null
GSE234637_1_v_0_ikzf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
COL1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82122
NCOR-22465074-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NDUFAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51049
GSE166920_6_v_5_adalimumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97465
GSE217776,GSE217829_1_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellar white matter	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12799
BHLHE40_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158815_1_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
STAT3	ENCODE Transcription Factor Targets	1.0	null
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1615
MYO10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.096
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.13603
GTEX-W5WG-0008-SM-4KL25	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
GSE88819_5_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NFYB_02_24	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.39232
PMC5668942-supp_gr.216721.116_Supplemental_Data_S2.xlsx-Artery_Tibial_IR-TE-SRCAP_SRCAP	Rummagene Transcription Factor Associations 2026	1.0	null
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.05901
GSE149943_2_v_0_cd8a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_24_macaque_DRSG_lowerRes-Hg_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U412-0008-SM-4DXTE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
Sapanisertib_C32	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0164228
PD-70-VS77_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.206999
GTEx Brain 20-29 vs 30-39	GTEx Tissue-Specific Aging Signatures	-1.0	-3.012
NOP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81597
496100431_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09705
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4916-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Posterolateral visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05922
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IGR1	CCLE Cell Line Gene CNV Profiles	1.0	1.7276
GTEX-QXCU-0006-SM-2TC5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1923
GSE192663_3_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE147662_2_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.461599
CXCL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76537
mammalian	GeneRIF Biological Term Annotations	1.0	null
SUM159PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.631282
OVTOKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.829491
CENPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73286
NRBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34421
MT-CO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65857
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5175
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.65641
GSE171712_0_v_1_scgb1a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8405-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell projection organization	GO Biological Process Annotations 2025	1.0	null
cuneus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.832614
SSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55587
PAPSS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29065
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Pupa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.814
GTEX-UPK5-0008-SM-4IHJD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
AC-84-QG99_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.213129
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4714-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848828
GSE176008_7_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YK-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Microglial cell_Embryonic prefrontal cortex_Human	CellMarker Gene-Cell Type Associations	1.0	null
GSE76425_0_v_3_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BK-01B-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LOVO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DI-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841783
PPM1H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10205
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978458
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19998
GSE157777_1_v_3_foxa3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.18378
Accessory olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14344
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.72218
PMC3677161__F5	PFOCR Pathway Figure Associations 2023	1.0	null
Supramammillary nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35158
GSE166004_3_v_4_pld1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
perimammillary part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05015
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE183251_4_v_0_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FKBP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46384
GSE247862,GSE247863_0_v_5_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
THEM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72522
18818702-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
EP300_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE246195,GSE246305_2_v_5_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MED9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58361
Tubulin folding cofactor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.32
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST-18959480-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-RNOR-0526-SM-2TF4O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00166
CLK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69113
GSE146074_0_v_3_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GALNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23769
blood	GTEx Tissue Gene Expression Profiles	1.0	1.2211
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5986
cytoskeleton	GO Cellular Component Annotations 2023	1.0	null
CJUN-26792858-CHIP-SEQ-BT549-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
psychotic disorder	GWASdb SNP-Disease Associations	1.0	0.231147
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.03697
Adenoid cystic carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13726
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837358
GSE146074_9_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Fibronectin fibril	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.191
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.337
GSE125157_1_v_0_piceatannol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CLOCK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95777
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6I0-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PGA1	DepMap CRISPR Gene Dependency	1.0	3.27037
outer SZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.155
GTEX-PVOW-0008-SM-48TE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38827
TBL1XR1_02_43	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.32193
GSE68155_3_v_2_gpr3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UPIC-0002-SM-3NMDC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861861
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HK-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBMX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.45078
KDM2B-26808549-CHIP-SEQ-DND41-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_16733_KO_Hpgd_SRP049141	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.71228
Arcuate hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17053
Adult Oligodendroglioma	DisGeNET Gene-Disease Associations	1.0	null
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KIF13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.91178
SUSD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95858
RAD54L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58983
GSE135350_3_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88754
MAFK	ENCODE Transcription Factor Targets	1.0	null
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.97212
ARIH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17187
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.0357
PVRIG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41553
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.968885
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907956
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Purkinje cell layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08713
lateral part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37691
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72531
PHYHIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67354
DD-36-YH76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.346027
arteriosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.286187
Leukocyte adhesion deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.437
GTEX-X5EB-0008-SM-46MU3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-NB4-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_NB4_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-5963-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DYNC1LI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17983
ANO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98517
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5191-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU620	DepMap CRISPR Gene Dependency	1.0	8.75839
GSE173232_1_v_0_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HB-06-WU12_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.393614
HCFC1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-QVJO-0008-SM-447AU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32559
PMC4487811-mmc3.xlsx-siRE_enriched_geneLists-siRE_occupancy_pattern_gene_lists_after_RUNX1_ETO_knock_down_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
periventricular stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2276
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Chronic Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
HIF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09506
fasciola cinerea	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19132
GTEX-XXEK-0008-SM-4BRW7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37444
GSE180200,GSE180201_12_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
Supraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13278
GSE246195,GSE246305_1_v_3_sin3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lamellipodium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.626
GSE168076,GSE168080_1_v_0_batf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AP2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00594
GSE88819_11_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE229468,GSE229471_2_v_1_znf587_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.88759
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38164
RBMY1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.091
CGB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.77754
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.48157
COMMD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57829
GSE223008_4_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NEUROD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87815
FMNL1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11408
Supramammillary nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51841
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE135350_2_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
retromammillary area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58447
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852185
GSE145915_5_v_4_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE137325_2_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ANKRD34B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36296
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845923
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868112
FF-28-ES17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.580751
ASH2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58569
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NOP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01264
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CAKI-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.919216
CB-16-SY72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.373133
GSDMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02334
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
ventral part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32019
superficial stratum of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19239
PMC4205566__F1	PFOCR Pathway Figure Associations 2023	1.0	null
H3K36me3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.957368
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15546
PTX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62561
CDK6_knockdown_93_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.4149
FAM91A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63405
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52674
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.987556
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.959291
GTEX-P4QS-0926-SM-48TBS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43812
SIKE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73937
r2 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2276
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8047442-EMBJ-40-e105492-s003.xlsx-MR_plot_analysis-Gene_names_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.179
GTEX-WCDI-0008-SM-47JYE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11121
Cortical microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.861
cell adhesion	GO Biological Process Annotations 2015	1.0	null
MARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66308
PMC5842026-mmc5.xlsx-HIC1_directTargets_48h-Gene_symbol_HIC1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE66014_0_v_1_perhexiline_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44647
NELFE	ENCODE Transcription Factor Targets	1.0	null
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3QD-01A-32R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE164463_2_v_1_pax6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151829,GSE151831_7_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ALLSIL	CCLE Cell Line Gene CNV Profiles	-1.0	-1.8345
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041251
medial superior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09988
16651414-Supp2	GeneSigDB Published Gene Signatures	1.0	null
GSE202434,GSE202438_10_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
ZNF281	ChEA Transcription Factor Targets	1.0	null
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.922808
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDELR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21423
GTEX-SUCS-0008-SM-4DM53	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A5KG-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-REY6-0426-SM-2TF5G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919565
AD-51-FB60_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.478126
foxa2_20483781_p15_lung_lof_mouse_gpl1261_gse19204	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.149782
VZ in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.65355
GSE145476_2_v_0_hopx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
LMO2-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE101336_1_v_0_decitabine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE109913_1_v_2_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE110268_2_v_3_foxd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VAMP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31968
GTEX-TMMY-0008-SM-4DXU3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
Bladder	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE175787_5_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28044
HE-80-BQ08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.218922
GSE154767_4_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ventral premammillary nucleus (migrated)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00566
GTEX-R55F-1226-SM-2TF59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.970498
PANC0403	DepMap CRISPR Gene Dependency	1.0	2.05691
RNF103	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03498
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5645395__F6	PFOCR Pathway Figure Associations 2024	1.0	null
cell-substrate junction	GO Cellular Component Annotations 2025	1.0	null
GTEX-T2YK-0008-SM-4DM6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
GSE152432_5_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CXCR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53792
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3236
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.872651
ENDOV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.33253
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TNFAIP8L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21917
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WV-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Filopodium tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.641
FTSJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00945
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EP-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE179036_1_v_0_trim24_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CB-99-OG76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.234673
GSE234637_2_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9941
r1 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69406
SARS-CoV MA15_Day7-C57BL-6_None_GSE40824	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.92812
Brain Lower Grade Glioma_LGG_TCGA-S9-A6UA-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NB17	DepMap CRISPR Gene Dependency	1.0	3.32827
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AS-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.099
cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.051194
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DF-84-RT50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205208
GSE174498,GSE174500_5_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BS-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.982754
GB-57-XV52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.744032
ZNF462	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65597
GSE224969,GSE224971_0_v_7_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PLCG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11083
PMC6347838-13046_2019_1042_MOESM3_ESM.xls-PRDM16_group_peak_anno-Gene_PRDM16	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4819-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BE-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.1693
PM20D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15428
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7059-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
small intestine	GTEx Tissue Gene Expression Profiles	1.0	0.871973
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975254
medial trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.60844
lung	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HSPA12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67245
GSE190534,GSE190536_0_v_3_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-A53D-01A-32R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05147
EGR1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE110178_2_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
globose nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.944856
H3K4me1_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Anchoring junction	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
rostral periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05354
HCC1143	CCLE Cell Line Gene CNV Profiles	1.0	1.34282
RFX5	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IU-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SYT12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97421
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
GTEX-XUJ4-0226-SM-4BOP8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45894
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.75609
GTEX-SNOS-0008-SM-4DM6I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27067
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE220600_1_v_2_clpp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MYC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nb4	HPA Cell Line Gene Expression Profiles	1.0	0.871938
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain - Anterior cingulate cortex (BA24)	GTEx Tissue Gene Expression Profiles 2023	1.0	3.92427
GSE193282_2_v_0_cd44_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.81801
VZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.87599
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-E2A_Pre-Pro-B-Cells_ChIP-seq_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.307
GSE247159_8_v_3_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Microglial cell_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8597
MARCHF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91765
RUNX2	ChEA Transcription Factor Targets	1.0	null
GSE113106_3_v_4_dnm2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PC-68-DU31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.301129
Dystroglycan complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.075
primary motor-sensory cortex (samples)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.826461
FES	Kinase Library Tyrosine Kinome Atlas	1.0	97.94
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3351-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPI1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
kidney_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.94915
intermediate stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74201
Lung adenocarcinoma_LUAD_TCGA-55-8513-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NDUFA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16033
SIRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92685
FDXR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78136
Cerebellar nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32823
HC-11 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.806
SW48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10338
GSE222758_0_v_3_clofazimine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GC-04-UF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222119
parathyroid gland	HPA Tissue Protein Expression Profiles	-1.0	-1.14355
Megalencephalic leukoencephalopathy with subcortical cysts	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.121
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_12hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-WN-A9G9-01A-12R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3426-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RVPU-0008-SM-3NM8B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26138
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00893
STAT5A	ENCODE Transcription Factor Targets	1.0	null
Perturb_1229_KD_HNRNPK_SRP033393	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-13.8723
PITPNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07627
GSE120612_6_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7468443-Data_Sheet_5.xlsx-LPS_2h_over_6h-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
496100592_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.30689
CCDC134	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91011
GSE168401_1_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	1.0	null
NB7	DepMap CRISPR Gene Dependency	1.0	3.22437
GSE149124,GSE149128_3_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cortex of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08096
Tcf21	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.2156
PMC8016886-41419_2021_3630_MOESM6_ESM.xlsx-Sheet1-Table_S5_Differentially_expressed_genes_identified_between_HOXC6-low_and_HOXC6-high_expression_CRCs_using_TCGA_cohort_HOXC6	Rummagene Transcription Factor Associations 2026	1.0	null
ORAI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58996
promonocytic leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.377996
PMC4256277__F2	PFOCR Pathway Figure Associations 2023	1.0	null
non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.366
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1298
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00807
inferior temporal gyrus, right, bank of the its	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.914474
GSE174498,GSE174500_5_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
TPRA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81793
TCF7	ChEA Transcription Factor Targets	1.0	null
cell-substrate junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.678543
DPM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86726
MYC_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
submammillothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39656
NCIH2073	CCLE Cell Line Gene CNV Profiles	1.0	1.68638
SNU478	CCLE Cell Line Gene CNV Profiles	1.0	1.38061
Neurological pain disorder_Dorsal Root Ganglia_GSE15041	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.43753
SIRT6	ENCODE Transcription Factor Targets	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-ND-A4W6-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE135350_2_v_7_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NR2E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15216
GTEX-WRHU-0006-SM-3MJF6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.96133
Integrin alpha5-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.574
BTBD17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41735
KURAMOCHI	CCLE Cell Line Gene Expression Profiles	-1.0	-2.36132
RAP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99276
ARMC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18237
GSE74528_0_v_1_trex2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-O5YT-0008-SM-4E3IQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6324-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202434,GSE202438_3_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Dendritic filopodium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.691
GSE60217_1_v_10_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
no abnormal phenotype detected	MGI Mouse Phenotype Associations 2023	1.0	null
oligodendroglioma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.923387
SPRED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54638
GSE154337_0_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RAB3GAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88741
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7DV-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE128240_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GB2	DepMap CRISPR Gene Dependency	1.0	2.25039
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE180200,GSE180201_15_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Colorectal Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
GTEX-PLZ6-1526-SM-2S1OC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06166
JA-26-YQ32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.309052
JAG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44389
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.12383
GTF3C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41298
TPCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.185
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_55_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
lymphnode_5b	HPA Tissue Sample Gene Expression Profiles	1.0	0.889774
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13756
orbital frontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09613
GTEX-XUW1-0005-SM-4BOQ7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27147
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PDXK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36826
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05814
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
actin filament-based process	GO Biological Process Annotations 2015	1.0	null
GSE165682_0_v_1_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PRR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44314
TBL1XR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46647
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4496
MRPL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6804
BET1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62185
H2AC20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29913
superficial stratum of PHyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07023
GTEX-XV7Q-0008-SM-4BRWL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27161
Sarcoma_SARC_TCGA-K1-A6RT-01A-32R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE184884_4_v_1_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.56
molecular_function	GO Molecular Function Annotations 2015	1.0	null
GTEX-T8EM-0006-SM-3DB71	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01947
MEIS1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ES-I3 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.94969
GSE139992_1_v_0_mboat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
medial mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.87044
16166618-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	1.0	0.868122
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1187
BACH1	ENCODE Transcription Factor Targets	1.0	null
GTEX-R55E-0526-SM-2TC6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.979043
EOLA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04831
Lung adenocarcinoma_LUAD_TCGA-97-A4M6-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRSF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.21403
HDAC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18067
IL17RE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69124
Perturb_15031_Mut_Csf33_SRP347624	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GSE126463_5_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE100316_5_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE207611,GSE207612_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MTCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91853
PL4	DepMap CRISPR Gene Dependency	1.0	7.53839
Integrin alpha11-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.893
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8903
BRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23497
SP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.40232
GTEX-RU1J-0008-SM-46MV9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16412
IZ in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03937
Brain Lower Grade Glioma_LGG_TCGA-HT-7857-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F4	ENCODE Transcription Factor Targets	1.0	null
GTEX-UJMC-0008-SM-4IHKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37456
ATP5PF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46193
KA-29-AB08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.296206
GTEX-S7SE-0926-SM-2XCD6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873046
GTEX-WH7G-1626-SM-4LVMY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15279
GTEX-OHPL-0008-SM-4E3I9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
YA-78-MS95_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.603836
NOC4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23057
GSE182680,GSE182683_10_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
FA-63-WI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.341025
central nervous system disease	GWASdb SNP-Disease Associations	1.0	0.085194
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A656-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RWSA-0008-SM-47JYX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13178
OLFM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48913
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.71677
LE-40-JW92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.477257
TP53INP2_KO_GDS5053_544_mouse_skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
tolerance	GeneRIF Biological Term Annotations	1.0	null
SAFB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86909
GH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61544
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TTYH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39875
GSE166920_6_v_8_adalimumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
C2orf81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11998
mediodorsal nucleus of thalamus_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.93588
primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12732
mediodorsal nucleus of thalamus_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17126
cytoskeleton organization	GO Biological Process Annotations 2015	1.0	null
oligodendroglia	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.327164
GSE235550_1_v_0_hspa9_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAPKAPK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26128
TE-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MFF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99606
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87905
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SEMA6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64127
outer SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22708
salivary gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.140709
GTEX-OOBJ-0926-SM-48TDO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.76575
GSE182680,GSE182683_10_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
OGFOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53959
NFYA_02_76	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	7.01123
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041061
Lung adenocarcinoma_LUAD_TCGA-93-A4JQ-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TP63	ChEA Transcription Factor Targets	1.0	null
DF-95-CY55_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.449064
VZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.847816
GSE89767_7_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210580_0_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WVLH-0011-R11A-SM-3MJFO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874004
Six3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.6287
GTEX-OIZG-0008-SM-4E3J2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
Perturb_2121_KD_PRMT5_SRP276651	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.25087
Hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.23913
PMC4013678__F2	PFOCR Pathway Figure Associations 2023	1.0	null
OCIAML2	CCLE Cell Line Gene Expression Profiles	1.0	2.87044
GSE214931_4_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Anterior cingulate area, dorsal part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4975
NCIH1915	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61668
POLR2A_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4319	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
ZNF165	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80365
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.970321
TSSK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98452
GOLM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74346
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
VA-48-RJ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.301906
APEH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41587
lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.225395
BA-84-WN26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211768
r9 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18676
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.9512
Syntrophin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.776
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MFSD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9754
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.840363
IZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.31427
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
PDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49956
EGR1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_2_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Respiratory system_CT1_neutrophil	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
alzheimer disease	GWASdb SNP-Phenotype Associations	1.0	0.472241
GTEX-P4PP-0926-SM-48TBZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989845
cell junction	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
BV173 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.764
SPI1-23547873-NB4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R2-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DHDDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83184
TUBB2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49979
TIE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26126
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Q9WMX2	Virus MINT Protein-Viral Protein Interactions	1.0	null
PMC12528040-Data_Sheet_1.pdf-15-KLF4_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
YD-49-HM53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.822644
GTEX-XUZC-2126-SM-4BRW8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877161
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MRPS18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51246
Ebolavirus(EBOV)_1day_PBMCs_17725815_GSE8317	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	0.19695
GSE120415,GSE120447_0_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
amygdaloid complex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.86691
APH1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79192
NRL_Deficiency_GDS1693_237_mouse_Photoreceptors cells of retinas at P6	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GALNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89371
initial	GeneRIF Biological Term Annotations	1.0	null
oral cavity cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.122578
SKMEL2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53127
BMPR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71505
GTEX-QXCU-1726-SM-2TC6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841699
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-7353-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Actin filament bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.826
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2923
GSE226355,GSE226357_1_v_4_ybx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE234155_7_v_1_nfix_human	RummaGEO Gene Perturbation Signatures	1.0	null
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.17001
FE-56-PV35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.338378
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Ventromedial hypothalamic nucleus, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05918
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
hsa-miR-4301	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.961644
HNRNPUL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99017
SKNSH	DepMap CRISPR Gene Dependency	1.0	4.00247
cell projection assembly	GO Biological Process Annotations 2023	1.0	null
OLIG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28507
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
SUPHD1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77971
KIF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25605
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050951
striatum_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.94662
laminin-11 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.654
Prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
GSE128730_7_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U8XE-0008-SM-4E3K4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48549
SLC38A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.47081
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.14225
Retrochiasmatic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31601
G3BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32539
lymph node	HPA Tissue Gene Expression Profiles	1.0	1.03085
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE230329_0_v_3_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047707
Brain Lower Grade Glioma_LGG_TCGA-HT-8013-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
t66-lung_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.47486
GSE210580_5_v_2_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UNC119	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05018
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_4_chimp_DRSG_higherRes-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PB-18-HD85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.305934
superficial stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18676
GTEX-X4XY-0626-SM-4E3IN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.977
medial (fastigial) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.98028
cell-substrate adherens junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.690326
ATP6AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64522
FLT1_knockdown_111_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.83382
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE95077_5_v_2_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CHD2_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hyperphosphatemic familial tumoral calcinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.215
GTEX-TKQ2-0008-SM-4DM5L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
Lung squamous cell carcinoma_LUSC_TCGA-85-A4PA-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-2.05408
CPNE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46492
TUSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53095
GTEX-PW2O-1726-SM-2S1OO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917032
PMC5687749-pone.0188272.s005.xlsx-Supplementary_Table_3-Supplementary_Table_3_Differentially_Expressed_Genes_in_Common_between_AFX_compared_to_both_Keratinocytes_and_Fibroblasts_FOXO4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE113106_3_v_5_dnm2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20165
DCUN1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16985
GTEX-POYW-0526-SM-2XCEY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.84368
intermediate stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59281
hsa-miR-758	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.241414
Integrin signaling	KEGG Pathways 2026	1.0	null
PMC10042887-41419_2023_5742_MOESM4_ESM.xlsx-Table_S4-Table_S4_Overlap_genes_of_HOXB3_vs_HOXB3-_and_APC-KO_vs_APC-intact_HOXB3	Rummagene Transcription Factor Associations 2026	1.0	null
ZDHHC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96565
t67-small-intestine_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.47285
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8658
GSE218580_1_v_2_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-P4PP-1026-SM-3NM9O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.944182
DND41	CCLE Cell Line Gene Expression Profiles	1.0	1.37967
PMC8043114-Table_7.xlsx-PE1-gene_name_s_ETV3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE180200,GSE180201_5_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POU2F2_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.2408
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9629
GSE181966_0_v_3_has2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NR2F2_02_19	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.66297
PL21	CCLE Cell Line Gene Expression Profiles	1.0	1.48662
Primary motor area, Layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66222
GSE213632_3_v_5_acod1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	1.0	0.912564
abnormality of the coronary arteries	GWASdb SNP-Phenotype Associations	1.0	0.318467
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20O-01A-21R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE56235_1_v_0_prdm11_human	RummaGEO Gene Perturbation Signatures	-1.0	null
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.309843
primary motor-sensory cortex (samples)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.21024
MORN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11981
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	1.0	2.29333
GTEX-P4QS-1626-SM-2S1NH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857584
GSE160817_3_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158715_3_v_0_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DIXDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55205
t69-brown-adipose_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	6.63214
Urinary system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE110178_4_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Urinary tract	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23762
GSE178255_1_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.101
Leading edge of lamellipodium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.267
GSE107956,GSE107957_0_v_1_ythdf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.799
dorsolateral part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95657
SG in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.61068
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HL-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CIITA-18437201-Raji B cells and iDC-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4728-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
BEND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79365
16103065-Table2	GeneSigDB Published Gene Signatures	1.0	null
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.87443
GTEX-WEY5-0008-SM-4LMKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
NIFK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12525
SIN3A	ENCODE Transcription Factor Targets	1.0	null
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40762
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GSE110178_4_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Prepupa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.565
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63641
CEBPB_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DHX33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4612
ZNF354C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35692
GSE182770,GSE182784_0_v_1_chd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MXD3_02_83	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.88264
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40762
NACC1	Pathway Commons Protein-Protein Interactions	1.0	null
FGFR1_knockdown_94_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.86706
19549311-SuppTable2-MMLandPhenotype	GeneSigDB Published Gene Signatures	1.0	null
GSE167546_1_v_2_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NFATC1_02_22	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.0
GSE180200,GSE180201_15_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S7PM-0011-R6A-SM-3NM8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879975
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5VV-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XOTO-0011-R11B-SM-4B64O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04024
GTEX-T6MN-0008-SM-4DM7H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17575
lymphoid tissue	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.902127
GTEX-R55E-0006-SM-2TC5G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37141
GSE157777_1_v_0_foxa3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MIR140_OE_GDS3461_575_mouse_C3H10T1/2 fibroblast cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NCI-H650	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE178255_5_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.96984
Thymic carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.568
cerebellar nuclei of CbV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.982
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965147
Reticulum trabeculare	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.789
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36887
GSE159206_1_v_3_drd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Primary somatosensory area, mouth, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.17865
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
GSE228894_0_v_1_rnmt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE215086_8_v_6_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
ADPRH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43475
MTERF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65782
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB-26923725-CHIP-SEQ-MESODERM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE102505_5_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE135030_3_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_11347_KO_Hdac3_SRP360955	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.37656
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE229468,GSE229471_2_v_3_znf587_human	RummaGEO Gene Perturbation Signatures	1.0	null
C1RL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5375
cell-substrate adhesion	GO Biological Process Annotations 2015	1.0	null
AKAP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98222
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NANOG-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.869259
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NDUFAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63265
TAF1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.354
TMEM42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03153
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.31315
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227764
KIFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91484
GTEX-XUW1-0008-SM-4BOQH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24047
GLB1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94682
SBNO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37814
estradiol_mus musculus_gpl4134_gse23072	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE242083,GSE242098_2_v_0_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
STEEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31272
BCL11A	ENCODE Transcription Factor Targets	1.0	null
TMEM79	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39067
cell-substrate adherens junction	GO Cellular Component Annotations 2015	1.0	null
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19802
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0549
disease	GWASdb SNP-Disease Associations	1.0	0.037696
SPI1_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4231
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Tuberomammillary nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37785
ovary	HPA Tissue Protein Expression Profiles	-1.0	-1.14355
GSE176008_7_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.946204
GSE100316_7_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE76425_0_v_5_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SLC4A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03133
GSE94849_6_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RTLS-2326-SM-46MUH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907644
GSE103068_5_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T5JC-0226-SM-32PMA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02469
Primary somatosensory area, upper limb, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55967
substantia nigra, reticular part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00294
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042133
GTEX-WZTO-0826-SM-3NM8Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.958545
GSE226259_0_v_1_scd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.273
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.9176
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GALR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00574
MAPK8IP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51938
GSE202434,GSE202438_8_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69334
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC10933434-44319_2024_69_MOESM1_ESM.xls-HRV16_vs_MI-Associated_Gene_Name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
SOX2-21211035-LN229_GBM-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPV-0008-SM-47JYW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23273
PF-59-CY33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205421
DNAJA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.37701
GSE178255_2_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883706
GSE103068_5_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HW-A5KK-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AD-16-HL96_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.528383
GSE126777_0_v_1_otub1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE125862_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11119
GSE178255_3_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
amygdaloid complex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.882323
GTEX-WFG8-0001-SM-4LVN8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887379
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.8237
hippocampus (hippocampal formation)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.69677
GSE101239_5_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63785
appendices_4c	HPA Tissue Sample Gene Expression Profiles	1.0	0.875345
H3K4me1_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
abnormalities of the peripheral arteries	GWASdb SNP-Phenotype Associations	1.0	0.257243
H3K79me2_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE71491_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZE-45-CG69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.954982
GSE205163,GSE205164_5_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.181
outer SZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01034
IZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22506
KB-78-BE93_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.32767
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE226091,GSE226092_3_v_1_sall1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE157296,GSE157298_4_v_3_kbtbd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE180277_0_v_1_bach2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XPVG-0008-SM-4GICH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26037
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901083
POU6F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30842
UBE2G2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88604
T3M4	CCLE Cell Line Gene CNV Profiles	1.0	1.76399
GSE210476_9_v_8_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
T3M10	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39058
GSE221577_1_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91721
HOMER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54396
KELLY	CCLE Cell Line Gene CNV Profiles	1.0	1.39115
superficial stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42704
peripheral neuropathy	GWASdb SNP-Phenotype Associations	1.0	0.381704
PMC12410147-NIHMS2099518-supplement-3.xlsx-z-scores_DEGs_DGATi_LPS_vs_LPS-Z-scores_for_genes_differentially_expressed_when_comparing_DGATi_LPS_treatment_to_LPS_alone_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE140651,GSE140653_2_v_0_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Integrin alpha8-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.075
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2615
RELA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51309
frontalcortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.93926
RCBTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33828
ERBB3_knockdown_65_GSE19921	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.72299
GB-46-CK08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.287127
ZNF766	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43293
GTEX-XMD1-0008-SM-4AT41	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29679
GSE229914_2_v_3_keap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
LCLC-103H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.69407
non-membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
Integrin alphav-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.847
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H3-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85333
Perturb_17401_KD_HMGCR_SRP216293	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.56979
TP53_01_37	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.6188
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14004
a-HCV5 ()	NURSA Protein Complexes	1.0	null
GSE144347_1_v_0_crnkl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.1273
GSE122711_2_v_3_mpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE100316_7_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SMG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3805
Nucleus of the lateral olfactory tract, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17261
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.166
GTEX-PLZ6-0008-SM-48TD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11362
PMC10561055-mmc3.xlsx-LPS_T2-gene_name_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49233
uterus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.911054
orbital frontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.943135
EP300	ChEA Transcription Factor Targets	1.0	null
SKM1	CCLE Cell Line Gene Expression Profiles	1.0	2.03501
GTEX-UTHO-0726-SM-3GAEN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895856
anchoring junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.604017
arterial stenosis	GWASdb SNP-Phenotype Associations	1.0	0.257243
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
intermediate stratum of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67248
GSE152432_5_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-657	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
BPNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47671
DGKQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57589
REC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44758
NFE2L1_02_32	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.67243
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039912
CAMK2N1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4047
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A1HT-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
isthmic vestibulocerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04115
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PRDM14-21183938-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CNNM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19852
KMS-28PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27687
PMC6743792__F7	PFOCR Pathway Figure Associations 2024	1.0	null
ELF1	ENCODE Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CF-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE147366_1_v_4_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAGEE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26807
GSE136742,GSE136744_0_v_3_setd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A5RJ-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BD-A2L6-11A-21R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.247008
Perturb_11094_KO_Regnase1_DRP004811	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	17.4023
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.61221
GSE164757,GSE164759_1_v_3_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-R3RS-0008-SM-48FF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
GSE245134_2_v_3_atg5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
focal adhesion	GO Cellular Component Annotations 2015	1.0	null
GTEX-XMD3-0008-SM-4AT4V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06993
Brain Lower Grade Glioma_LGG_TCGA-HT-8106-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYDGF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76976
TBX3-20139965-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NO36	DepMap CRISPR Gene Dependency	1.0	2.1041
Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NM-01A-21R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE145323,GSE145324_9_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SOX10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5655
GSE201309_5_v_7_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.303
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.001
paracentral lobule, anterior part, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08446
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.55419
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.894685
rostral (anterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18184
Spleen	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-XYKS-0008-SM-4BRW6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58598
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23415
GSE182680,GSE182683_7_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE190235_0_v_2_foxo3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE98964_0_v_2_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SLC16A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15034
NELFE_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJHI-0126-SM-4IHLP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66314
LHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29919
PMC7887593-ADVS-8-2003526-s002.xlsx-TT_AR_vs_BR-Gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
actin cytoskeleton reorganization	GO Biological Process Annotations 2023	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-A56U-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE174735_1_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COLO741	CCLE Cell Line Gene CNV Profiles	1.0	2.96119
CHD7	ENCODE Transcription Factor Targets	1.0	null
GSE148692,GSE148695_1_v_4_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
coronary artery disease	GWASdb SNP-Phenotype Associations	1.0	0.351977
spleen	GTEx Tissue Gene Expression Profiles	1.0	1.79626
GSE223008_5_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26796
striatum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.18378
ruffle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.505537
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.152
RNASEH2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11713
H3K4me1_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE149903_0_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DCAF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76784
Rectum adenocarcinoma_READ_TCGA-DC-6156-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
evolution	GeneRIF Biological Term Annotations	1.0	null
GSE171175,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09136
GSE133683_3_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE223008_0_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06071
GSE118765_1_v_5_rreb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
hsa-miR-4480	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-Kasumi-1-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_Kasumi-1_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
Primary motor area, Layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12994
TFDP1_02_71	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.80735
MXI1	ENCODE Transcription Factor Targets	1.0	null
H4C5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68281
Lobules IV-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32393
POLR2AphosphoS5_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-8007-11A-01R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21732
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
TRIM28-17542650-NTERA2-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Immune system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
all	GWASdb SNP-Phenotype Associations	1.0	0.03421
Supramammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38225
HES7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6104
ZNF837	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56669
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54D-01A-21R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE160304,GSE163392_4_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE182680,GSE182683_10_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Brain - Frontal Cortex (BA9)	GTEx Tissue Gene Expression Profiles 2023	1.0	5.12004
SW620	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.44574
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-O5YT-0926-SM-48TDG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45094
GTEX-P44H-0008-SM-48TDW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08668
GSE149075_6_v_4_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SPARC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43192
DCTD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85144
RPS21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55447
FBXO17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9938
Obstructive sleep apnea_Hepatic Tissue_GSE1873	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.84093
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854525
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE174498,GSE174500_2_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13663
PAX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05326
superficial stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12732
GMPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85234
GTEX-T2IS-0008-SM-4DM75	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37897
Muscle tendon junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.47
ACTG1	Hub Proteins Protein-Protein Interactions	1.0	null
PMC8126329__F1	PFOCR Pathway Figure Associations 2024	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10773
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CG-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Integrin alphav-beta8 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.703
atherosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.318467
USF2	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE151612_4_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
H6PD_KO_GDS3195_602_mouse_Skeletal muscle - Soleus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CREM	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7735
NCIH3255	CCLE Cell Line Gene Expression Profiles	-1.0	-1.55276
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.39105
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GT-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202434,GSE202438_13_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GGA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04366
REST-18959480-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CEBPB-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MAGED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16336
lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066669
OCT4-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
JAR	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OE33	DepMap CRISPR Gene Dependency	1.0	2.86767
GSE185519_3_v_5_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2451
TMOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11651
HCC1195	CCLE Cell Line Gene CNV Profiles	-1.0	-1.93505
Brain Lower Grade Glioma_LGG_TCGA-HT-A74O-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ITGAV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86926
DEF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.04989
superficial stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93113
Renal agenesis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.262
ZNF559	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51874
GSE114883_0_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Rectum adenocarcinoma_READ_TCGA-DT-5265-01A-21R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UF-27-HS98_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.267694
FASN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17242
cerebellar cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.14245
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.627
FOXK2_02_31	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.39232
mantle zone of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.87889
H2AK5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_10187_KD_RUNX1|ETO_SRP035930	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.5938
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.8145
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.20919
AD-16-HL96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.693866
RND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3411
USF2_02_25	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	7.54689
GSE143212_1_v_2_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE188570,GSE188571_5_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PUR1	MotifMap Predicted Transcription Factor Targets	1.0	null
PDCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82919
GSE152432_1_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-V1-A8MM-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PLZ6-0126-SM-48TC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20293
GSE153124_4_v_3_dsg2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Integrin alphaL-beta2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.757
SPI1-23547873-NB4-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
STRIP1	Pathway Commons Protein-Protein Interactions	1.0	null
focal adhesion	GO Cellular Component Annotations 2025	1.0	null
GTEX-WRHK-1726-SM-3MJFK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904281
Cecal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.98
GSE203060_0_v_2_kdm4c_human	RummaGEO Gene Perturbation Signatures	1.0	null
SPATS2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21362
GSE149903_6_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
THRAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00074
C8orf76	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32861
MRNIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35765
GSE167886_2_v_1_chd7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC24A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41014
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36078
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.866296
PRKACB_knockdown_91_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.87461
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1783
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.987556
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.948752
GSE146074_1_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.95495
MATN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36611
JHOM2B	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46993
GSE182179_5_v_4_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
inner CP in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2551
CREB1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GGN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49481
GSE89767_1_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR1H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22536
CL11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47745
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0056
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3C8-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849567
sensory neuropathy	GWASdb SNP-Phenotype Associations	1.0	0.381704
planum temporale, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.70665
SH4	DepMap CRISPR Gene Dependency	1.0	9.02956
AB-33-EM56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210416
r3 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14626
BCL3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AF-99-HA02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214199
GSE199899_3_v_2_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4637-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF628	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52787
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Dentate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59844
GRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77852
SECISBP2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48157
Acute Myeloid Leukemia_LAML_TCGA-AB-2943-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE100316_5_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE117212,GSE117214_0_v_1_zbtb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EGR1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45654
ZNF337	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98863
RBM17_02_138	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.0
lateral orbital frontal cortex (area 12/47)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.912174
RNF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49322
SLITRK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68817
RUNX3	ENCODE Transcription Factor Targets	1.0	null
ODR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77563
hsa-miR-939	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
SOX11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4362
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28809
cell-substrate junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.514
X, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12819
GSE155567_3_v_0_cd33_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.33097
Perturb_16510_OE_Tafazzin_SRP284254	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
IRF2_01_100	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.10142
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21881
Mesothelioma_MESO_TCGA-TS-A7OY-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ctnnb1_21914722_ls174t_lof_human_gpl570_gds4386	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.355017
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041396
GTEX-XMK1-0008-SM-4GICF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53186
layer 6a of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0756
ZNF284	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96833
blood	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE202434,GSE202438_4_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SPI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
focal adhesion	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.693832
GSE240468_3_v_6_nfyc_human	RummaGEO Gene Perturbation Signatures	1.0	null
JUND_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE128730_4_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	1.0	2.10794
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KM-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE146072_0_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
XA-12-UL84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.242741
GSE143643,GSE143644_3_v_5_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Metabolite levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.6
Lung adenocarcinoma_LUAD_TCGA-44-7669-01A-21R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STRN3	Pathway Commons Protein-Protein Interactions	1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050441
SPI1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Glanzmann's thrombasthenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.146
NCBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95517
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.50207
NE-20-WM78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.269197
INTS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25995
GTEX-RM2N-0008-SM-48FF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27123
GSE144443_5_v_6_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF230	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94657
Accessory olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36267
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12279
ZNF182	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81421
sensory system disease	GWASdb SNP-Disease Associations	1.0	0.720957
Lobules IV-V, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38415
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-R2-A69V-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XQ8I-1726-SM-4BOQB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64924
RAB11FIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30184
KRT19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41478
ADD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18706
GSE103068_0_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09972
H3K27ac_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03693
inferior occipital gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.26578
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE100528_1_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
gh1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.573
GSE60217_1_v_0_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZIC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44636
GTEX-QV44-0008-SM-447AX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1042
GSE152432_1_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LK-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r5BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33176
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.994372
DB-54-GQ68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.347886
IKBKE_knockdown_97_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.69694
GSE218060_2_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16039
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57584
FLT4_knockdown_103_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.76295
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
MICAL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8905
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935233
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55031
pou5f1_20526341_human_embryonic_stem_cells_hesc_lof_human_gpl6947_gse21135	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.447705
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.924388
GSE129241_4_v_6_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PIGO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80519
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.037
hsa-miR-762	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
JL1	DepMap CRISPR Gene Dependency	1.0	2.18969
KMS34	DepMap CRISPR Gene Dependency	1.0	2.97103
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58317
amygdaloid complex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25137
Lung squamous cell carcinoma_LUSC_TCGA-56-8201-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SSA3-0008-SM-47JWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2717
DACH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11541
Perturb_10694_KD_Kat7_SRP174052	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Lung adenocarcinoma_LUAD_TCGA-55-6969-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE63048_11_v_8_morc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCA1	DepMap CRISPR Gene Dependency	1.0	2.11845
GSE152637_1_v_0_imiquimod_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91604
NR3C1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
ZNF384	ENCODE Transcription Factor Targets	1.0	null
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06764
Lung adenocarcinoma_LUAD_TCGA-55-8510-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NB5	DepMap CRISPR Gene Dependency	1.0	2.14011
NAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5504
POLR2AphosphoS5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TGBC18TKB	DepMap CRISPR Gene Dependency	1.0	2.27299
LCN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07215
GGH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81742
LINGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02378
USP24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87524
EPLC272H	CCLE Cell Line Gene CNV Profiles	1.0	1.49109
ChIP_PRDM14_21183938	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE169152_5_v_6_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
perimammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66061
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
blood cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055779
POLR2A_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01337
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7369
GSE178255_2_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
17192395-TableS2b	GeneSigDB Published Gene Signatures	1.0	null
GSE188832,GSE188835_0_v_1_irf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193624_1_v_0_med1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53035
GTEX-QCQG-0226-SM-48U28	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39549
GSE185519_3_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.56735
GTEX-VJYA-0126-SM-4KL1P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46991
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12573
YH13	CCLE Cell Line Gene Expression Profiles	-1.0	-2.00478
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-S4Q7-0008-SM-3NM8A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
GSE120612_7_v_2_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
STAT6	MotifMap Predicted Transcription Factor Targets	1.0	null
RPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.69344
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
CTBP1_02_41	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.80735
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.366
GTEX-R55G-0008-SM-48FEX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41439
SLMAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5825
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.64501
GTEX-QEL4-0826-SM-3GAF2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838297
alzheimer's disease	GWASdb SNP-Disease Associations	1.0	0.55372
Integrin-linked kinase signaling	PID Pathways	1.0	null
GSE202434,GSE202438_15_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE216043_11_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ruffle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.400527
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NR-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE159937_2_v_0_tfcp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CHD2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTTNBP2NL	Pathway Commons Protein-Protein Interactions	1.0	null
UBE4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22593
Actin cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05189
POLR2AphosphoS5_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09219
GSE114883_0_v_4_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94088
PPP2R1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04541
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE111102,GSE111105_4_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13881
PMC9894241-pnas.2211429119.sd05.xlsx-G3_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9170821-JCMM-26-3183-s001.xlsx-Mic_DAPI_ERG_VaDadj_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
PAX5	ENCODE Transcription Factor Targets	1.0	null
intracellular non-membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
GSE144120_3_v_1_plcg2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Mammary epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.278
SUCLG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.71339
GSE178255_1_v_0_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S7PM-0526-SM-3NM92	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.878774
TUBA4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4928
GSE126463_1_v_3_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07325
A-Netherlands-602-2009(H1N1)_0Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.09075
GSE210580_5_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RAB1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49624
Respiratory system_CT1_basophil	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
SPI1	ENCODE Transcription Factor Targets	1.0	null
496100537_FWM_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.13294
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04851
SOX2	ChEA Transcription Factor Targets	1.0	null
intermediate stratum of PHyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04318
GTEX-U3ZM-1226-SM-3DB9G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.891467
ILF2_02_70	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.80735
IER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35403
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A1OD-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.304503
DUSP28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48641
COX4I1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99012
GSE114992,GSE114993_8_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_8591_KO_Fto_SRP097869	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.7362
GSE160817_2_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X4EO-0926-SM-3P5Z2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21921
MV411	CCLE Cell Line Gene Expression Profiles	1.0	2.63116
GSE79291_1_v_2_streptozotocin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-SIU7-0226-SM-4BRX2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0814
Magnocellular reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18746
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27866
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
GDM1	CCLE Cell Line Gene Expression Profiles	1.0	2.01489
PA-75-VL17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.25532
HIGD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56311
GSE182680,GSE182683_7_v_9_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
ERBB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19348
PMC4013678__F2	PFOCR Pathway Figure Associations 2024	1.0	null
mantle zone of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19239
Adrenocortical carcinoma_ACC_TCGA-OR-A5JV-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14172
H3K79me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
operational	GeneRIF Biological Term Annotations	1.0	null
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935948
GSE254848_9_v_8_ptges_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE123022,GSE123030_8_v_0_trem2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE114258_1_v_0_foxk1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXM1	ENCODE Transcription Factor Targets	1.0	null
GSE180200,GSE180201_3_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SELENOV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8657
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HJ-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OGFOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.87144
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15452
PMC9038526-mmc1.xlsx-postCOVID_ctr_vs_LPS-symbols_98_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10561055-mmc3.xlsx-LPS_T0-gene_name_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33154
GTEX-S3XE-0526-SM-4AD4G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.910576
GSE205070_2_v_9_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.046797
GTEX-QVUS-0226-SM-3GIJY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06805
GSE120612_7_v_3_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
orbital frontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.34412
Kidney cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.071
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.920144
GSE149075_6_v_5_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ventrolateral periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02313
SNRPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56577
GAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45959
DRAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67438
Lung squamous cell carcinoma_LUSC_TCGA-46-6026-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE192870_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE72491_0_v_1_pcbp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE188570,GSE188571_3_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MLEC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60826
intermediate stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28907
FB-66-UU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.499977
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11039
SNU410	DepMap CRISPR Gene Dependency	1.0	2.81551
GSE128730_0_v_1_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE151782_2_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DPH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73922
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE165682_0_v_3_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4815-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR3C1_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.13833
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE236502_2_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
leukocyte	GeneRIF Biological Term Annotations	1.0	null
ZNF384_02_203	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.48113
GSE238018_1_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.61428
posterior part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11475
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15438
GSE183413_0_v_2_ash1l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
MDAMB435S	CCLE Cell Line Gene CNV Profiles	1.0	1.74332
Dorsal premammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17506
GSE176008_0_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.7592
CD-35-BD44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.450541
GSE92457_7_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QCQG-0008-SM-48U2G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0926
Hemidesmosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.179
GSE88819_3_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE128730_7_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE79663_2_v_0_tcf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211983_0_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Brain_CT2_Mgl 9	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
cell-matrix adhesion	GO Biological Process Annotations 2023	1.0	null
SIKE1	Pathway Commons Protein-Protein Interactions	1.0	null
HS578T	CCLE Cell Line Gene CNV Profiles	1.0	1.41728
AARD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5562
salivary gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.286381
HADHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67398
Vermal regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05617
GSE89018_10_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HES2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.926
biological_process	GO Biological Process Annotations 2015	1.0	null
CF-50-QK79_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.263181
THUMPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27871
GTEX-XUZC-0008-SM-4BOQG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09494
IGF2R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60297
GTEX-P78B-0008-SM-48TE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23977
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30188
RPAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97547
CLN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40646
organelle organization	GO Biological Process Annotations 2015	1.0	null
KCNAB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08147
ventrolateral prefrontal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.842059
GSE160817_3_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40397
CHTOP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24802
GSE146074_10_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE144231_2_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A6J3-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AH-0626-SM-48TZJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846196
posterior (caudal) superior temporal cortex (area 22c)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33287
GTEX-OXRK-0008-SM-3NB28	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18501
TIMELESS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45189
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83286
TMEM147	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42008
ARID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73508
Sarcoma_SARC_TCGA-SG-A849-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE178255_5_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KYSE-150	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.871844
IZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.900262
GTEX-WQUQ-0006-SM-3MJF4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52958
GTEX-X4XY-1726-SM-46MVO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840656
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.213
Integrin alpha10-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.859
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOT4-0008-SM-4B664	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.992204
Acute Myeloid Leukemia_LAML_TCGA-AB-2908-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-4626-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VUSH-0008-SM-47JWK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62214
tonsil	HPA Tissue Gene Expression Profiles	1.0	0.833222
GSE160817_2_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X585-0008-SM-46MU4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36893
NFYB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AF-41-QY60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.324463
GSE149903_0_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.6854
ARMC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98552
EE-98-PF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.484584
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.967633
TSPAN17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60282
ZDHHC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48274
hsa-miR-330-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055497
GSE136238_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TTLL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42308
TMEM35A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47544
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04901
DDX24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.06194
GTEX-TKQ2-0826-SM-33HB6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.92105
mantle zone of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17326
PLA2G12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.20742
BRCA1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKMEL19	DepMap CRISPR Gene Dependency	1.0	2.36241
substantia nigra reticulata, isthmic part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10692
Actin filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.761
ZFX_01_157	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.68081
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.958595
GSE248858_6_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GD-66-XE49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.42452
GSE114883_1_v_5_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-TSE9-0008-SM-4DXT8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42976
Integrin alphav-beta5 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.074
outer SZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.941997
GSE236502_1_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5169-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06764
ARL5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38407
intermediate stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72567
GTEX-P44H-0426-SM-2XCEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.961234
GSE126463_1_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-PWOO-0008-SM-48TDU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
Rectum adenocarcinoma_READ_TCGA-AF-2690-01A-02R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24246
GSE147943_0_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCOLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07621
Anterior cingulate area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.16461
GSE116354,GSE117379_2_v_4_cox2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Dilated cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.307
NDUFV3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85668
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
integrinlinked	GeneRIF Biological Term Annotations	1.0	null
SP in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.978163
Arp2/3 protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.429
Tuberomammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12531
GTEX-Q734-0226-SM-48U1A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10295
GSE114258_1_v_2_foxk1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11309649-medi-103-e37185-s002.xlsx-Sheet1-FOS_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
lateral mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93036
r8 part of the paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12797
SLC12A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77894
GSE154767_2_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
STRN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87622
CB-11-GB40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.530926
mantle zone of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10659
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4217-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11093744-41592_2024_2172_MOESM3_ESM.xlsx-ELP-genes_NR5A1	Rummagene Transcription Factor Associations 2026	1.0	null
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.988718
FF-86-NH56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.40949
GTEX-QLQW-0126-SM-447BK	GTEx Tissue Sample Gene Expression Profiles	1.0	2.27256
PK-59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11458
GSE106170_1_v_0_nap1l3_human	RummaGEO Gene Perturbation Signatures	1.0	null
dorsolateral part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75177
UTY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03709
DE-62-FI29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.326924
GSE202434,GSE202438_10_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16974
GSE85880,GSE85881_0_v_2_tretinoin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PCYT1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25427
posteroventral (inferior) parietal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.36502
GSE146074_0_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5012
lateral mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05722
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.40006
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.4528
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216043_7_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
cell junction	GO Cellular Component Annotations 2015	1.0	null
ALMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21399
JVE015	DepMap CRISPR Gene Dependency	1.0	2.2266
mantle zone of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65833
Sarcoma_SARC_TCGA-DX-A7ET-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.053
ABC1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.06334
TBP_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
neuropeptide-S nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0288
GSE185519_3_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE201309_1_v_6_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
HEK-AD293 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.315
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60224
GTEX-O5YV-2026-SM-2D7VS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.862067
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
Rectum adenocarcinoma_READ_TCGA-AG-3902-01A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28163
DLX1_02_55	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.64386
REST_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41308
GTEX-P4QR-0008-SM-48TE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
DCAF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58576
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A5RH-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.87678
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE202434,GSE202438_6_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCFC1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
protein binding	GO Molecular Function Annotations 2015	1.0	null
PMC6743792__F7	PFOCR Pathway Figure Associations 2023	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.632
GTEX-UJMC-2026-SM-3GADR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830816
GDAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38578
tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33331
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.435
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7861-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GD-73-ZF64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.212384
GSE123002_0_v_1_srsf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nucleus of the solitary tract, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20971
Lung adenocarcinoma_LUAD_TCGA-78-8648-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
dorsolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.892233
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60358
MAFK_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CENPE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1632
EOL1	CCLE Cell Line Gene Expression Profiles	1.0	1.93783
GSE86507,GSE86509_7_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Actomyosin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.914
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A5DY-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIGM5	CCLE Cell Line Gene Expression Profiles	1.0	1.59027
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21881
layer I of piriform cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.925764
GSE152432_1_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
striatum_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.9574
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40762
Perturb_1182_KD_RUNX1_ERP128097	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	17.2518
GSE227891_2_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.50462
GTEX-UJHI-0008-SM-4IHL1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
lateral trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33214
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70506
Perturb_638_KD_GATA3_SRP372594	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.08127
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
white matter of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52582
BC-25-VR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.373425
DZIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96722
GTEX-POYW-1326-SM-48TCG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.902377
GSE62292,GSE62295_2_v_0_col4a3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4486	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
AB-21-VE32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.269414
THBS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80637
medial geniculate complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05974
SRD5A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86574
hsa-miR-125b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
ICC3	DepMap CRISPR Gene Dependency	1.0	3.50977
Adrenocortical carcinoma_ACC_TCGA-OR-A5JK-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cortical amygdalar area, posterior part, lateral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0887
GTEX-R53T-0008-SM-48FEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
Prostate adenocarcinoma_PRAD_TCGA-V1-A8MU-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-5333-01A-01R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QEG5-0426-SM-2I5GJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.992752
GSE174735_4_v_0_il22_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
outer CP in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04786
GSE176008_4_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Myosin X complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.409
A-Vietnam-1203_CIP048_RG4-2004(H5N1)HAAvirmut_7day-MOI-10^4_None_GSE37572	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.69262
GTEX-QMR6-1326-SM-32PLB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841657
CEBPA-20513432-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_16521_KD_ASXL3_SRP247927	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE148692,GSE148695_1_v_6_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lobules IV-V, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23357
GSE139911_0_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.101
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.2283
CHD1	ENCODE Transcription Factor Targets	1.0	null
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07172
PMC11167707-JCMM-28-e18392-s006.xlsx-corr_lnc_with_mRNA_up_R_0_8-L3MBTL4_AS1_L3MBTL4	Rummagene Transcription Factor Associations 2026	1.0	null
Declive (VI)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34275
NFATC1	ENCODE Transcription Factor Targets	1.0	null
ERG28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66298
GTEX-VUSG-1726-SM-4KKZL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99418
Focal adhesion	KEGG Pathways 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A6W2-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
focal adhesion	GO Cellular Component Annotations 2023	1.0	null
OSBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40497
MTFMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06997
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44262
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08102
ALAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01487
NCI-H2228	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27758
GTEX-S4UY-0008-SM-3NM8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29887
single-organism process	GO Biological Process Annotations 2015	1.0	null
GSE155305_3_v_0_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SHISA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19031
Primary somatosensory area, mouth, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75177
GSE126463_6_v_3_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90195
SCML4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56068
ACTG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39223
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
I band	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.323
outer SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.57612
RUNX1_01_93	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.97671
TRIM28-17542650-NTERA2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7222-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83122
GSE152432_6_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9904760-elife-79363-supp2.xlsx-MDS1-Gene_MECOM	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26532
migration	GeneRIF Biological Term Annotations	1.0	null
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H727	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.36229
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.918965
thyroid gland	HPA Tissue Protein Expression Profiles	1.0	2.53285
GTEX-S7SE-0005-SM-2XCEA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37274
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KLK13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60687
GTEX-SNMC-0008-SM-4DM5A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39052
GSE146074_6_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.071
GTEX-QV31-1426-SM-2S1QD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.95956
hippocampus (hippocampal formation)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.53916
GSE227415_1_v_0_ucp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE94849_6_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
phi1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.833
PMC5105166-ncomms13331-s5.xlsx-Sheet1-Supplementary_Data_4_Gene_expression_signature_of_MEF2D-rearranged_cases_stranded_data_only_MEF2D	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UNC13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23932
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-XPVG-0626-SM-4B65B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10927
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mammillary area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.87817
GSE162688_3_v_4_pink1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151782_2_v_7_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PIDD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25554
outer CP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.920581
NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05558
Perturb_1001_KO_Adar1_SRP360154	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.8111
GSE141143_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
ABC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.92664
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NPY1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89286
polymorphisms	GeneRIF Biological Term Annotations	1.0	null
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SEC62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14138
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-8470-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXA1	JASPAR Predicted Transcription Factor Targets	1.0	null
U937	CCLE Cell Line Gene CNV Profiles	-1.0	-2.28953
Palatine tonsil_CT1_CD4 T cell	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CREB1	ENCODE Transcription Factor Targets	1.0	null
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57717
SNU213	DepMap CRISPR Gene Dependency	1.0	2.04043
SNU685	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51832
GSE169152_5_v_7_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051453
FD-91-OK66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.298048
Temporal association areas, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39405
ZFP30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12362
FAM111A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7811
NCI-H510A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CUEDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20321
GTEX-PSDG-0008-SM-48TE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42549
GSE169152_5_v_4_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
u937	HPA Cell Line Gene Expression Profiles	1.0	0.886074
Respiratory system_CT1_naive thymus-derived CD4-positive, alpha-beta T cell	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02017
IPAF inflammasome complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.042
SUPT11	CCLE Cell Line Gene CNV Profiles	1.0	1.91363
GSE223008_11_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RMDN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68678
RBM47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43874
GSE210476_2_v_0_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BIRC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41465
MEIS2_02_30	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	6.18982
C19orf81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22936
RXRA-24833708-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MBD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95527
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01453
H3C13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42201
NID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2043
H3K4me1_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SEMA4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34241
GTEX-XV7Q-0126-SM-4BRVK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950116
CABLES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56035
TNFRSF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14957
Acute Myeloid Leukemia_LAML_TCGA-AB-2861-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KDM2B-26808549-CHIP-SEQ-SUP-B15-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
amygdaloid complex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.65553
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.912641
GSE143830_0_v_1_trex1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.31904
isthmic roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02351
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE171837_0_v_3_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
DG-75	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE240896,GSE240899_3_v_0_ccnt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF143	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53936
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.0302
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.845076
CDCA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44513
59M	DepMap CRISPR Gene Dependency	1.0	2.65345
GSE154074_5_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7UY-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051658
WC-09-GD62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.417446
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.99112
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24427
GTEX-UTHO-0008-SM-4JBID	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.394
respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.6204
FGFR1OP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84381
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3WY-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9288051-13046_2022_2428_MOESM4_ESM.xlsx-Super_enhancers_in_AML2-CLOSEST_GENE_RUNX3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10561055-mmc3.xlsx-LPS_T2-hgnc_symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
STK24	Pathway Commons Protein-Protein Interactions	1.0	null
STMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32284
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4346-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.02308
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45269
MRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34314
GSE168807_0_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146074_6_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6433273-pone.0214296.s009.xlsx-Table_C-S3_Table_Differentially_expressed_mRNAs_in_human_primary_monocytes_after_6_hours_of_LPS_stimulation_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Well Differentiated Oligodendroglioma	DisGeNET Gene-Disease Associations	1.0	null
MALSU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77489
GSE229671,GSE229673_3_v_1_yrdc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5751-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4274
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PRICKLE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31379
GTEX-UPK5-2026-SM-4JBIM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67714
GSE146074_9_v_3_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE203158_1_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.857861
MANSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00812
GSE149903_6_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WH7G-0008-SM-4LVNM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18148
paresthesia	GWASdb SNP-Phenotype Associations	1.0	0.621094
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-U3ZH-0008-SM-4DXT2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28884
GSE128730_4_v_1_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
18450603-Table3S	GeneSigDB Published Gene Signatures	1.0	null
MZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04812
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cuneus, left, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.836444
GTEX-XLM4-0008-SM-4AT4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17996
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_FIGLA-Unnamed_2_FIGLA	Rummagene Transcription Factor Associations 2026	1.0	null
STRADB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24711
PDGFRB_knockdown_114_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.69828
GSE185519_4_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-TKQ1-1426-SM-4GICK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.981337
r8 part of inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21479
HCC1187	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.625379
GTEX-R55E-0008-SM-48FCG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
GSE111385_0_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NRF1_02_62	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.0
CIITA-25753668-RAJI-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-T6MO-0008-SM-4DM6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30175
PFKFB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43935
POLR2AphosphoS2_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFYB	ENCODE Transcription Factor Targets	1.0	null
Sarcoma_SARC_TCGA-DX-A8BQ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
biological adhesion	GO Biological Process Annotations 2015	1.0	null
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2798
actin filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.276671
NUDT21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7166
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11384
Lung adenocarcinoma_LUAD_TCGA-L4-A4E6-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Somatomotor areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07716
GTEX-T5JW-0126-SM-4DM6K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56506
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55494
GSE147834_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE114013,GSE114014_0_v_3_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40118
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.900262
STRN	Pathway Commons Protein-Protein Interactions	1.0	null
TNNC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33227
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SLC22A23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67142
Stalk cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.69
MDA-MB-435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.41014
Integrin alpha1-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.585
ZNF700	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4791
GSE154767_2_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H4K20me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NRL_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12191
GSE149124,GSE149128_3_v_1_cdk7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8554124-DataSheet2.XLSX-57-CEBPD_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF200	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56968
hsa-miR-1470	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21744
PMC4256277__F2	PFOCR Pathway Figure Associations 2024	1.0	null
GSE200352_5_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
rostral division of VL	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16282
PRORP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84699
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831668
Unconventional myosin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.24
GTEX-P78B-0926-SM-2I5FA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944331
ACOT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40562
GID4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52716
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044491
lateral (dentate) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01884
FLT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12507
PEG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25381
GSE120612_4_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
JHH7	CCLE Cell Line Gene CNV Profiles	1.0	1.48512
GSE207611,GSE207612_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-A4P8-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.00145
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6V1-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5J8-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
precentral gyrus, right, superior lateral aspect of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.27092
TAOK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94613
GSE114992,GSE114993_8_v_3_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE113106_0_v_4_dnm2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.6695
CFAP157	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48509
GSE88819_0_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE178255_1_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148510_3_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DPH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43611
RCOR1	ENCODE Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YL-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10852026-sxad088_suppl_supplementary_tables.pdf-93-NFATC2_NFATC2	Rummagene Transcription Factor Associations 2026	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.38792
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG8-0008-SM-4LVN6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10326
GATA3	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE161771_0_v_1_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-92b-3p	MiRTarBase microRNA Targets	1.0	null
dorsolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.877435
GTEX-Q2AH-1826-SM-2S1Q2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917551
Brain Lower Grade Glioma_LGG_TCGA-HT-8563-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GOLT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37893
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
KLF2_02_29	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.85798
Heschl's gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18083
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Perturb_12958_KO_KDSR_SRP308393	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.72137
no abnormal phenotype detected	MPO Gene-Phenotype Associations	1.0	null
CD151	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07706
CAPZB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50344
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
WC-09-GD62_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.374127
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42214
they	GeneRIF Biological Term Annotations	1.0	null
Rectum adenocarcinoma_READ_TCGA-AH-6547-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE144443_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48661
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3625
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33924
GSE160373_8_v_2_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE223893_2_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
IRF4	ENCODE Transcription Factor Targets	1.0	null
Integrin alpha6-beta4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.158
intermediate stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10559
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-2K-A9WE-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dystrophin-associated glycoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.074
CISH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75015
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.050946
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7079-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01458
GTEX-OHPM-0008-SM-4E3IP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
SRY	ChEA Transcription Factor Targets	1.0	null
BC-01-JL64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.350032
CTCF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8497824-Table_4.xlsx-Stage_4_EOMES_vs_Ctrl-Unnamed_1_EOMES	Rummagene Transcription Factor Associations 2026	1.0	null
CITED2_02_38	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.70044
GTEX-T5JC-0008-SM-4DM6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
GSE152441,GSE152442_7_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_62_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE226091,GSE226092_0_v_4_sall1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Sarcoma_SARC_TCGA-DX-A6BE-01A-41R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
22RV1	DepMap CRISPR Gene Dependency	1.0	9.45033
SLC16A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09233
GSE125014_1_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
leading edge membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.127694
Liver hepatocellular carcinoma_LIHC_TCGA-K7-A5RG-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular component assembly	GO Biological Process Annotations 2023	1.0	null
CAL148	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62264
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.757
Intercalated disc	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.862
SKIL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44809
lateral group of nuclei, right, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.943583
SMC3	ENCODE Transcription Factor Targets	1.0	null
HSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73648
GSE102505_5_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
filamentous actin	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.392001
GSE147943_7_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUS-01A-12R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Urinary bladder	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NECTIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01388
DBTRG05MG	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82578
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	1.0	1.22346
Fasting glucose	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.530103
CEBPB	JASPAR Predicted Transcription Factor Targets	1.0	null
ZNF680	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46246
GSE216043_10_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-4498	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GTEX-OIZI-0626-SM-2XCEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.924976
abnormality of the systemic arterial tree	GWASdb SNP-Phenotype Associations	1.0	0.149175
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30788
abnormality of nervous system morphology	GWASdb SNP-Phenotype Associations	1.0	0.121821
WT1-25993318-PODOCYTE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE128730_4_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PRDM14	ChEA Transcription Factor Targets	1.0	null
Perturb_2001_KO_Irf8_SRP265130	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Prostate adenocarcinoma_PRAD_TCGA-HC-8266-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
eye disease	GWASdb SNP-Disease Associations	1.0	0.119467
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_FIGLA-Unnamed_3_FIGLA	Rummagene Transcription Factor Associations 2026	1.0	null
skin	GTEx Tissue Gene Expression Profiles	-1.0	-1.15718
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.60529
Mammillary body	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60488
bladder	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
LRRN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28007
Orbital area, medial part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07779
GSE206226_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Z disc	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.365
ZNF143	ENCODE Transcription Factor Targets	1.0	null
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.3257
layer 3 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33754
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F4-06A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCL3	ENCODE Transcription Factor Targets	1.0	null
ATXN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94863
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.785969
cell-matrix adhesion	GO Biological Process Annotations 2025	1.0	null
Fanconi anaemia nuclear complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.193
PMC9794594-DataSheet_1.xlsx-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
actin cytoskeleton organization	GO Biological Process Annotations 2015	1.0	null
HCC2935	CCLE Cell Line Gene CNV Profiles	1.0	1.50362
NFE2L2_02_174	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.11548
GSE111102,GSE111105_1_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_7_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_17378_KD_Myc_SRP190223	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
FC-20-EQ58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.286118
posteroventral (inferior) parietal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.70516
ZNF554	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89233
GSE197564,GSE198513_2_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100652_PCx_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.00807
parvg	GeneRIF Biological Term Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A76A-01A-51R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_30min-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
MYORG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74921
FZD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60268
ZNG1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78622
MRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47498
Oligodendroglioma	DisGeNET Gene-Disease Associations	1.0	null
PNPLA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38109
superficial stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20479
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.315462
thyroid_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.909638
ELK1	ENCODE Transcription Factor Targets	1.0	null
HEY	DepMap CRISPR Gene Dependency	1.0	2.55096
organelle	GO Cellular Component Annotations 2015	1.0	null
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BT-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9174260-41467_2022_30960_MOESM6_ESM.xlsx-S3-RAS2_unique_GATA2-Gene_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7410-01A-21R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
duplication	GeneRIF Biological Term Annotations	1.0	null
GSE178255_1_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.922125
GSE180200,GSE180201_3_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.32268
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5295
TM9SF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16599
Prostate adenocarcinoma_PRAD_TCGA-KK-A7B2-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE86507,GSE86509_7_v_5_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Anterior cingulate area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49046
PMC5645395__F6	PFOCR Pathway Figure Associations 2023	1.0	null
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4Z8-0226-SM-4AD5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4626
medial part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10692
GTEX-X261-0326-SM-3NMD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04634
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2112
lymphoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057687
Integrin alpha3-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.314
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE216147_2_v_1_rbm20_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ETS1-22383799-G1ME-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
AC-93-LT43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215666
GSE110178_2_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26765
GTEX-TSE9-2226-SM-4DXUR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.991473
dorsolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02175
cell projection part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.048375
HC-74-HM63_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.341858
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.75976
SKIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12013
WAC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10158
FE-10-KQ78_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.47456
GTEX-P4QS-0008-SM-48TDY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
Kidney renal papillary cell carcinoma_KIRP_TCGA-4A-A93Y-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_1424_KD_RUNX3_SRP159180	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.392
UQCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77524
hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12387
CORL279	DepMap CRISPR Gene Dependency	1.0	2.68479
SKMEL28	CCLE Cell Line Gene CNV Profiles	1.0	1.79945
hsa-miR-4783-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Dense body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.664
cuneus, left, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.96508
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.73833
GBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55051
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.109
GSE166920_6_v_3_adalimumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FLI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4Z8-0008-SM-33HAZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56131
EID3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75348
MOLM13	CCLE Cell Line Gene Expression Profiles	1.0	1.84096
GSE174522_1_v_0_spp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GB-57-XV52_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.228616
JARID1B-DAIN-22020125-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
membrane	GO Cellular Component Annotations 2015	1.0	null
PMC8766486-42003_2021_2990_MOESM3_ESM.xlsx-ST18-Supplementary_Data_18_Gene_burden_for_deletions_by_subtype_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar nuclei of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26945
layer V of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18327
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_FIGLA-Unnamed_1_FIGLA	Rummagene Transcription Factor Associations 2026	1.0	null
Secondary motor area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00894
A431	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WFG8-2426-SM-3GILL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.866608
REST	ChEA Transcription Factor Targets	1.0	null
allograft	GeneRIF Biological Term Annotations	1.0	null
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.0887
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Nanog	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.3441
IZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12489
EC-62-OE64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.65173
GSE218580_1_v_5_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Focal adhesion	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.523
PKP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46936
NCIH1155	CCLE Cell Line Gene CNV Profiles	1.0	1.39985
USF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80094
GTEX-QMRM-0008-SM-447B1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12056
Perturb_14815_KD_Eral1_SRP293259	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.80489
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.050698
GSE125211_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Declive (VI), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22378
NB1643	DepMap CRISPR Gene Dependency	1.0	6.8193
laminin-8 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.708
GSE180200,GSE180201_3_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE231720,GSE231724_2_v_1_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_14865_KD_ZRSR2_SRP341591	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.46337
CLCN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44025
tauopathy	GWASdb SNP-Disease Associations	1.0	0.55372
GSE120612_6_v_3_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
vagina	HPA Tissue Protein Expression Profiles	-1.0	-1.14355
GTEX-X62O-0008-SM-46MU5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16247
496100666_HIP_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.92908
GSE58724_3_v_4_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.0807
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875517
glial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058585
Lung squamous cell carcinoma_LUSC_TCGA-85-7710-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytoplasm	GO Cellular Component Annotations 2015	1.0	null
CCDC153	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52988
GTEX-XBED-2626-SM-4E3J5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.962378
spleen_3b	HPA Tissue Sample Gene Expression Profiles	1.0	1.12117
Folium-tuber vermis (VII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.82663
MED20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99742
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7593-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE101527_0_v_1_smad4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
nrf1_22586274_liver_lof_mouse_gpl4134_gse35124	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.072016
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43U-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE114883_1_v_4_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intermediate stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24557
PMC4791243-oncotarget-06-43452-s006.xlsx-Supplementary_table_S5-Supplementary_table_S5_Differentially_expressed_genes_in_TP53_mutant_versus_TP53_wild_type_cell_lines_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.168
BCL11A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular component organization or biogenesis	GO Biological Process Annotations 2015	1.0	null
EP300-21415370-HL-1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
cd4.Tcell	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07371
GSE152432_3_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OIZI-0008-SM-2XCFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39488
GTEX-U4B1-1626-SM-3DB8N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900015
Respiratory system_CT1_CD4+ T cell resident memory	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
SLC5A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68375
FKBP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02496
Pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.085
TMEM175	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92331
BCLAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ICE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32351
GTEX-OHPK-0008-SM-4E3JL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52509
C15orf40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13896
ventral anterior nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18479
cochlear nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01041
superficial stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37149
TRAPPC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04592
PGR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7266
RPS18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07349
Accessory olfactory bulb, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.20736
ZNF727	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06846
GTEX-QESD-0008-SM-447B2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25939
Perturb_3240_OE_IK6_SRP136156	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.4482
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.959223
GSE199899_3_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
18974375-TableS5a	GeneSigDB Published Gene Signatures	1.0	null
HB-06-WU12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.244589
GSE228162_2_v_5_nr2f6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GJC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69278
Perturb_12132_KO_Irf8_SRP265130	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
SLC35B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34838
CPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5033
MAZ	ENCODE Transcription Factor Targets	1.0	null
GSE114883_0_v_5_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CEBPB-20176806-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874226
superficial stratum of r2BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0379
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26091
mediodorsal nucleus of thalamus_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.75184
CYB561	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55074
Lung squamous cell carcinoma_LUSC_TCGA-56-8309-11A-01R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02821
PMC4221415__F5	PFOCR Pathway Figure Associations 2023	1.0	null
GSE216043_11_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE146074_1_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
GSE206729_4_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
IGR-37	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.903319
GSE221577_3_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
outer SZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.850666
OCIAML5	CCLE Cell Line Gene Expression Profiles	1.0	1.98635
Perturb_14866_KD_ZRSR2_SRP341591	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10881
GSE201309_1_v_8_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
embryonic stem feeder layer	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.924416
23132-87	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SIX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92357
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16879
CMLT1	CCLE Cell Line Gene Expression Profiles	1.0	1.57296
GSE120612_7_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE210580_5_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
PGRMC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65435
PAX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66882
Perturb_16899_KO_Sp8/Sp9_SRP115902	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GSE157960_0_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12180985-BLOODA_ADV-2024-014495-mmc1.pdf-17-ZNF444_ZNF444	Rummagene Transcription Factor Associations 2026	1.0	null
DCPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64007
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7446
PMC12549544-mmc2.xlsx-AA_D1_VS_D7-Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.931025
FLI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Pancreatic carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.025
STAT5A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R45C-0008-SM-48FF2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8533
DDAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34827
GSE120336_0_v_2_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE217776,GSE217829_2_v_0_sgf29_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE180200,GSE180201_15_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.078933
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01319
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.25749
Childhood Oligodendroglioma	DisGeNET Gene-Disease Associations	1.0	null
ASRGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01882
MRPS14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06378
H3K9ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TMEM240	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53743
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Calponin homology domain	InterPro Predicted Protein Domain Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1IB-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BEND5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51535
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.045994
THAP1_02_46	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.32193
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WDR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22377
GSE223008_11_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ESYT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56454
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.303
cingulate gyrus, parietal part, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08685
single-organism organelle organization	GO Biological Process Annotations 2015	1.0	null
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.902127
CHAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63885
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4363
PMC12804025-mmc2.xlsx-LPS-Unnamed_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
F2RL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36343
SOCS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.561
ZNF677	Pathway Commons Protein-Protein Interactions	1.0	null
CLDN34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16156
MITF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6101
Blood-classical monocyte	Tabula Sapiens Gene-Cell Associations	1.0	6.99722
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20323
binding	GO Molecular Function Annotations 2015	1.0	null
PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
r2 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03857
CINP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22656
GSE86507,GSE86509_7_v_8_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K36me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE154074_1_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
medial (main) part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.92227
MYC_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.922125
Laminin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.305
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A66S-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE199899_4_v_2_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EJ-138 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.164
Declive (VI), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49854
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7SE-0008-SM-33HB1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60493
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A2I4-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE162739_7_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TSE9-0526-SM-3DB7Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.906168
GC-04-UF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.461226
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.445384
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_34_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE167886_2_v_0_chd7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SAMHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9993
hsa-miR-3937	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
ISCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24109
NCI-H1563	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8096-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular component organization	GO Biological Process Annotations 2015	1.0	null
parvins	GeneRIF Biological Term Annotations	1.0	null
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.44419
GTEX-POMQ-0126-SM-48TD6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15137
FANCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32228
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.42529
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3179
EP300-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.6669
Lung squamous cell carcinoma_LUSC_TCGA-51-4081-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.53699
actin binding	GO Molecular Function Annotations 2025	1.0	null
Leukocyte adhesion deficiency 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.011
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUP-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE203158_0_v_14_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-POMQ-0008-SM-48TE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1325
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.71979
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE231720,GSE231724_3_v_1_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44843
TP53INP2_KO_GDS5053_277_mouse_Skeletal muscle - SKM-KO	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
KMRC20	DepMap CRISPR Gene Dependency	1.0	2.2964
JUND_02_16	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.0
TRIP13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60481
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07097
KLF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5716
postcentral gyrus, right, bank of the posterior central sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18695
SMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61464
Lung adenocarcinoma_LUAD_TCGA-75-5122-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF722	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.77897
Cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.121
GTEX-XGQ4-0126-SM-4AT4H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6918
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052986
GSE139016_3_v_2_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE144443_5_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Nephrocyte diaphragm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.737
pineal gland	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.897034
GSE164757,GSE164759_1_v_0_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62858
Nucleus of the trapezoid body	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3916
SCN1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1155
H1-4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71636
GTEX-R3RS-0526-SM-3GADG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828044
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.858974
GSE120248,GSE120252_1_v_0_macf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26815
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923184
GSE216043_11_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
occipito-temporal gyrus, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02872
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-A4AQ-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EDEM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36973
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.034295
Integrin alphaX-beta2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.734
PMC4205566__F1	PFOCR Pathway Figure Associations 2024	1.0	null
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
central nucleus of the inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14073
LAMA-84	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.3703
Actin cap	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.741
CLN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.9646
CCDC34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49689
GSE157777_2_v_3_foxa3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Rimonabant_C32	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0254326
HL60	CCLE Cell Line Gene Expression Profiles	1.0	1.38522
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K36me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RASSF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01859
NF-21-HQ00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.412177
Lung squamous cell carcinoma_LUSC_TCGA-58-8386-11A-01R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5740757__F4	PFOCR Pathway Figure Associations 2023	1.0	null
Superior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06451
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30788
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64833
Perturb_794_KO_Tnfaip3_SRP332632	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
H3K4me1_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
LGALS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47207
actin binding	GO Molecular Function Annotations 2015	1.0	null
outer SZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09548
cytoskeletal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.051262
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE218060_1_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SPI1_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
MYL12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17776
intracellular part	GO Cellular Component Annotations 2015	1.0	null
mammillary part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57188
GSE178255_3_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08893
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE144231_2_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.3307
NA-30-HS87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.492334
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9853
TGFB1I1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31253
GSE169152_3_v_1_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10561055-mmc3.xlsx-LPS_T0-hgnc_symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.48192
TEN	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69953
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06833
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.835642
cell-substrate junction	GO Cellular Component Annotations 2023	1.0	null
GSE182179_0_v_4_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE152432_6_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2686
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04026
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.018
anterior (rostral) cingulate (medial prefrontal) cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.37921
Myosin filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.102
posteroventral (inferior) parietal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.94589
cell-substrate junction	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.862086
nr2c2_20864514_liver_1yo_lof_mouse_gpl4134_gse21903	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.510602
DA-85-SU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.233707
GTEX-S3XE-0626-SM-4AD6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44919
GTEX-PW2O-0126-SM-48TC8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34113
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.874435
ATF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HSPA14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08302
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886251
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
SLC39A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89271
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57384
H3K27ac_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04228
Perturb_17320_KO_miR106b~25_ERP121195	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.98724
GTEX-U3ZN-0126-SM-4DXUM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32536
STARD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72068
cell-substrate junction	GO Cellular Component Annotations 2015	1.0	null
NCBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08643
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25171
Acute Myeloid Leukemia_LAML_TCGA-AB-3005-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4798-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GTEX-OOBK-1626-SM-2HMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.96536
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.867485
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE145915_3_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IA-76-ZU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.27548
ANTXR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21695
GSE128730_0_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CCDC59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83665
Parvin	InterPro Predicted Protein Domain Annotations	1.0	null
BE-27-RQ61_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.386267
GTEX-XUJ4-0008-SM-4BOQI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06922
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052806
GTEX-U3ZM-0008-SM-4DXTQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.037
MYC_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0011-R11A-SM-32QOX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827549
IPO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82304
Lung squamous cell carcinoma_LUSC_TCGA-85-A513-01A-12R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZN-0008-SM-4DXTL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27774
AADAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34955
GSE195582_0_v_1_pim1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3M9-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S341-1826-SM-3K2AB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.824573
GSE180200,GSE180201_5_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TNFRSF21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46944
RNF182	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3566
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YE-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NOVA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03304
PPARA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46859
ACHN	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6726
tonsil_8e1	HPA Tissue Sample Gene Expression Profiles	1.0	0.878673
Dystrobrevin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.675
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14448
17676974-TableS5	GeneSigDB Published Gene Signatures	1.0	null
Perturb_1549_KO_Rpl23a_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.50406
Uropod	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.581
HS934T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.85945
BRCA1	ENCODE Transcription Factor Targets	1.0	null
RecQ family helicase-topoisomerase III complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.563
intermediate stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.869
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8T8-1426-SM-3DB9H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.881268
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FV-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OOBJ-0008-SM-3NB26	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14541
PPOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65057
GTEX-SUCS-0626-SM-32PM5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990307
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.6765
Respiratory system_CT1_mature NK T cell	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
GSE134191_6_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
POGK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17246
GSE116810_2_v_3_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-O5YW-0008-SM-4E3IE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
GSE193588_3_v_2_pax3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
anterior part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61252
Integrin alphav-beta6 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.751
EP300	ENCODE Transcription Factor Targets	1.0	null
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.922125
TBX20-22328084-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NCIH2228	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32878
GTEX-WFJO-0926-SM-4LVM2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25023
MV-4-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HOXB4_02_64	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.24793
PNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.28566
CTNNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84713
NPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88296
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.919216
MRPS18C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64443
GTEX-UJHI-0726-SM-3DB92	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84414
GSE242333_0_v_2_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
superficial stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.05836
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4887-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZFP281-27345836-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
REST_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4816-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ruffle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.834
FAHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94642
TMEM167A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53089
PRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89043
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.68974
exonintron	GeneRIF Biological Term Annotations	1.0	null
Squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.2009
AOB, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11541
PMC4072629__F3	PFOCR Pathway Figure Associations 2024	1.0	null
H3K79me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TCF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42684
BA-77-US35_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.226652
GSE238018_1_v_0_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SERPINE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49886
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92473
IRAK2_knockout_76_GSE24264	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	0.987477
GTEX-RN64-0008-SM-48FEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16732
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Posterolateral visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08156
GSE173873_12_v_13_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TBX3	ChEA Transcription Factor Targets	1.0	null
GSE185519_4_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_4141_KO_Apoe_SRP131850	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.32327
FAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45107
isthmic alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12265
RARG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44719
ventrolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.15508
basal part of terminal hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02474
DF-00-BU08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.466067
MAP2K1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13746
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
16166618-SuppTable4	GeneSigDB Published Gene Signatures	1.0	null
GTEX-S7SF-0008-SM-3NM8T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38593
PMS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47788
GSE151612_4_v_11_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-UPK5-1626-SM-4JBHI	GTEx Tissue Sample Gene Expression Profiles	1.0	2.05125
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51F-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Monocyte_Fetal kidney_Human	CellMarker Gene-Cell Type Associations	1.0	null
rhombomere 11	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0813
cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.162707
cellular process	GO Biological Process Annotations 2015	1.0	null
GSE148692,GSE148695_7_v_6_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cell projection assembly	GO Biological Process Annotations 2025	1.0	null
HEY1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4325
GTEX-X5EB-0426-SM-46MVY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10064
GSE223540_1_v_3_anxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9170821-JCMM-26-3183-s001.xlsx-Astro_DAPI_ERG_VaDadj_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q7-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX1-22412390-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE215086_5_v_6_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAPK1_knockdown_112_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.98699
AB-18-YN11_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.270328
GSE110178_1_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
schizophrenia	GWASdb SNP-Disease Associations	1.0	0.510157
hsa-miR-3691-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE152432_9_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-A5FZ-01A-31R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.099
orbital frontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05416
normal phenotype	MPO Gene-Phenotype Associations	1.0	null
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60837
JHH2	CCLE Cell Line Gene CNV Profiles	1.0	2.059
EXOSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86096
LRCH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55599
HESX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3511
cytoskeleton	GO Cellular Component Annotations 2025	1.0	null
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.97109
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Prostate adenocarcinoma_PRAD_TCGA-KK-A59V-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MOLT16	CCLE Cell Line Gene Expression Profiles	1.0	1.83055
GTEX-WWYW-0526-SM-3NB2W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.896444
EP300_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.375915
CDK9_knockdown_104_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.87824
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.283191
TMEM258	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3386
GTEX-XGQ4-0008-SM-4AT3Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11403
GSE178255_5_v_0_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r10 part of external cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37328
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.133
FOSL1	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TR-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PX3G-0006-SM-33HBQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24128
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZFP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14807
GSE60217_1_v_7_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SH3GLB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39803
GTEX-WEY5-2126-SM-3GILK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90367
NCIH292	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53322
PABPC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.64871
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.902127
KIF21A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18678
FOXP1_01_88	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.43732
GSE124410_3_v_0_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
esophagus	HPA Tissue Protein Expression Profiles	-1.0	-1.14355
TBCCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72068
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.892233
SPTSSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98175
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5092-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.976095
GSE185519_1_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
STAT3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826562
Perturb_1898_KO_Rbpj_SRP033707	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.35784
Folium-tuber vermis (VII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.0163
ZFHX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86765
bone	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.868511
striatum_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.38348
BCAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62999
GSE123502,GSE123504_1_v_0_chd4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_17377_KD_E2f1/Myc/Pparg/Stat6_SRP190223	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	18.4815
FF-86-NH56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.229558
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ARID1A-32646524-H9-HUMAN-BONEMARROW-LYMPHOMA	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WYVS-2326-SM-3NMAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832164
STEAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10875
RUNX2-22187159-C42B-HUMAN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
ventrolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.922032
PPIL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59522
H376	DepMap CRISPR Gene Dependency	1.0	2.21314
GSE151829,GSE151831_1_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A87Q-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bone_Marrow-monocyte	Tabula Sapiens Gene-Cell Associations	1.0	0.559713
mantle zone of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32019
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_24hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
NR1D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.08645
NCIH1869	CCLE Cell Line Gene CNV Profiles	1.0	1.62499
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.42627
UACA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20005
DLL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11717
NR3C2-34362910-WISTARRAT-HIPPOCAMPUS-STRESS	ChEA Transcription Factor Targets 2022	1.0	null
lateral periretromammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07058
REST	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4873-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAL1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Integrin alpha9-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.781
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19268
Dunn cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.786
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.958518
A-431	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.829491
GSE108614,GSE108615_3_v_2_setd1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40782
GTEX-QDVJ-0008-SM-48U2E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20136
GSE127970_2_v_3_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EMC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.6183
TCEA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47143
GTEX-PX3G-0926-SM-48U12	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17353
ADAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51499
Fastigial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.87331
GTEX-NFK9-0008-SM-4E3JE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8784
KLHL31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67319
Lung adenocarcinoma_LUAD_TCGA-O1-A52J-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08454
Respiratory system_CT1_classical inflammatory monocyte	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
POLR2A_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU2F2	ENCODE Transcription Factor Targets	1.0	null
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
Sarcoma_SARC_TCGA-DX-A3U6-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC7A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85958
Mammary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.286
inferior frontal gyrus, opercular part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.36433
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.302
IFT80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53331
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.51096
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04656
NCI-H2126	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.829491
COLO 679	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06003
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
WC-16-IR43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.357206
PMC8127234-12885_2021_8319_MOESM2_ESM.docx-0-CREB3L1_CREB3L1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE146074_9_v_11_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182179_5_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
NEK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43562
Rectum adenocarcinoma_READ_TCGA-EI-6917-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMRT-22465074-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TML8-1826-SM-32QOR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.995755
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.953437
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21744
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33111
MEIS1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50019
S0-EE-Y4UM_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.283147
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07555
GTEX-OHPN-0008-SM-4E3HW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54153
ZFP281-18757296-E14-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
AOB, mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4355
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CLC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17059
GSE174498,GSE174500_5_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
amygdaloid complex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01619
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.3989
ILK	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TP-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHMP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.74807
GLCCI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58724
GSE202434,GSE202438_10_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.005
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.66024
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_4_chimp_DRSG_higherRes-Hg_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.832872
KOSC2	DepMap CRISPR Gene Dependency	1.0	4.07903
shell part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10022
SOX2-21211035-LN229-GBM	ChEA Transcription Factor Targets 2022	1.0	null
skeletal muscle	HPA Tissue Protein Expression Profiles	-1.0	-1.14355
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE135350_3_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
UNC5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83447
HR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80724
dorsolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.40427
JD-44-KF86_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.268034
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70583
suprachiasmatic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11337
periventricular stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56886
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.01124
GTEX-TML8-0008-SM-4DXUI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
retromammillary area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57138
superficial stratum of IC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21713
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC3419980-leu201249x4.xls-H3K9Ac-RUNX1ETO_peaks_2fold-All_gene_regions_overlapping_with_RUNX1-ETO_peaks_changing_histone_acetylation_more_than_2-fold_after_knock-down_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
MXI1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NTHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19508
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21881
Primary motor area, Layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25249
Myosin II complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.424
layer 1 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07292
REXO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01927
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042343
hsa-miR-3164	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
CREB1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.824287
Lung squamous cell carcinoma_LUSC_TCGA-43-6143-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.27586
HSPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28655
viscus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.58149
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862236
SC-72-YW56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.270289
GTEX-XBED-0008-SM-47JWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43687
GTEX-XUYS-0008-SM-47JYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08593
precuneus, right, superior lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22495
SP2_02_42	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.41504
CTCF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03934
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26532
RFX5_02_61	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.70044
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.970321
mantle zone of PHyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05116
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940809
POLR2A_GM12891_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVN-0526-SM-48TZ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27243
TBP	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4971-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
laminin-5 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.807
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_Jurkat_ChIP-seq_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
terete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.05658
GTEX-WFON-0126-SM-4LVM9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81165
Uterine Carcinosarcoma_UCS_TCGA-N5-A59F-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CB-49-OG36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.69052
M14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SPI1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KIAA1191	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12332
GTEX-R55D-0008-SM-48FEV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
Perturb_11073_Mut_Tak1/Ripk1_SRP256942	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.16917
NBPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9475
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.234
MLMA	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.26981
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4992-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CA-60-LK14_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.341379
POLR2AphosphoS2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146074_10_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
P31FUJ	CCLE Cell Line Gene Expression Profiles	1.0	1.65602
r9 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51004
GSE135030_3_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Combined T cell and B cell immunodeficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.212
inner SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.12379
GSE208254_3_v_2_irf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-V1D1-0008-SM-4JBIJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25025
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041521
Sarcoglycan complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.624
ZDHHC19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77628
GTEX-P4PP-0326-SM-33HC4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877205
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8688
Lung adenocarcinoma_LUAD_TCGA-55-7728-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32348
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	1.0	0.949061
intracellular non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.161358
KMT5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41152
intermediate (interpositus) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39135
SLR20	DepMap CRISPR Gene Dependency	1.0	5.29718
KLC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85579
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.60659
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0476
PMC11716045-peerj-13-18816-s007.xlsx-Sheet1-ZNF440_ZNF440	Rummagene Transcription Factor Associations 2026	1.0	null
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.985762
inner SZ in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.50921
hippocampus (hippocampal formation)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10089
GSE180200,GSE180201_2_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE180200,GSE180201_2_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF718	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29376
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61941
PMC5927328-NIHMS77085-supplement-Table_S4.xlsx-Table_S4A_LPS_induced_genes_GO-Unnamed_15_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210580_5_v_6_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151829,GSE151831_7_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE203158_0_v_13_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE114883_1_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.515666
NCIH747	DepMap CRISPR Gene Dependency	1.0	3.94048
mouth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054433
cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17183
actin cytoskeleton	GO Cellular Component Annotations 2025	1.0	null
GSE199204,GSE211619_4_v_5_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
integrin	GeneRIF Biological Term Annotations	1.0	null
mediodorsal nucleus of thalamus_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.34678
H3K27ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.917793
SH2B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6517
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4492	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
late	GeneRIF Biological Term Annotations	1.0	null
RARB-24833708-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Stress fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.834
Filopodium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.342
GTEX-P4PP-0008-SM-48TDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12762
GTEX-WK11-2526-SM-3NM9Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01486
XPNPEP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79944
Culmen	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3222
POU3F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43402
cellular component assembly	GO Biological Process Annotations 2025	1.0	null
MDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24321
Perturb_16365_KO_Auf1_SRP076844	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.35808
GSE165579_0_v_1_opa1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BD-96-HO33_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.570022
GSE182179_0_v_1_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC35F5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24593
similar	GeneRIF Biological Term Annotations	1.0	null
GTEX-Q2AH-0008-SM-48U2J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39834
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042515
orbital frontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.881698
hsa-miR-3944-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
NFX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91138
neurodegenerative disease	GWASdb SNP-Disease Associations	1.0	0.244132
UBE2R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36596
KMS28BM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55688
superior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09993
MMP24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00012
layer 5 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24414
GTEX-QMR6-0008-SM-447AV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QG-01A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TKQ1-0003-SM-3NMAE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885211
GSE185519_4_v_5_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-WFJO-0008-SM-4LVN7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34794
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14505
GTEX-UJMC-0426-SM-4IHJF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37675
Bladder Urothelial Carcinoma_BLCA_TCGA-S5-A6DX-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZFYVE16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34811
superficial stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11475
GSE120612_4_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4989-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRPL24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92579
r7 part of parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20874
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100527_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.24188
DNAJB14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21288
retrotrapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49278
SLMAP	Pathway Commons Protein-Protein Interactions	1.0	null
HES5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0724
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.829491
rostral group of intralaminar nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.25604
NR3C1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
salivary gland adenoid cystic carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.874509
Prostate adenocarcinoma_PRAD_TCGA-J4-A6G1-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BBS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79642
Mesothelioma_MESO_TCGA-TS-A7P8-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KDM2B-26808549-CHIP-SEQ-SIL-ALL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
t69-brown-adipose_male_8w	MoTrPAC Rat Endurance Exercise Training	1.0	1.34548
CTNNB1	Pathway Commons Protein-Protein Interactions	1.0	null
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GSE147943_5_v_1_cited2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LU-139	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OIZG-0005-SM-2HMJC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16348
GSE95077_5_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
heart_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.828253
GTEX-NPJ8-0326-SM-2D7VV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886671
SNU410	CCLE Cell Line Gene CNV Profiles	1.0	1.75736
GSE205070_2_v_5_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
layer V of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13414
MCF7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48081
GSE201309_5_v_8_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05254
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02727
CASC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92679
behavioral abnormality	GWASdb SNP-Phenotype Associations	1.0	0.083939
FD-29-MM50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.236946
GTEX-QLQ7-0008-SM-447AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39523
lymphnode_4b	HPA Tissue Sample Gene Expression Profiles	1.0	1.06272
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.965246
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9R7-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.103
t61-colon_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.1675
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07969
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3232
TLE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38978
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.64322
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.985552
PTRHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81116
PCDHB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49937
r6 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42797
NEUROD2-26341353-CORTEX-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CIITA-18437201-RAJI-B-AND-IDC-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TOMM70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46643
amygdaloid complex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.29665
ZFP281-18757296-E14-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC6858560-NIHMS1538530-supplement-Supplementary_Tables.xlsx-Supplementary_Table_22-Supplementary_Table_22_Aberrant_Splicing_Events_in_TET2_SRSF2_co-mutated_AML_Patients_from_the_Beat-AML_cohort_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
RUSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3203
GTEX-PWN1-0008-SM-48TEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19975
NCI-H1155	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.87136
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE182680,GSE182683_7_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
SLC4A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47843
NCI-H1793	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
ZCCHC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00722
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837372
ZNF71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00824
PMC10149505-41392_2023_1393_MOESM2_ESM.xlsx-CPCMR-Hugo_Symbol_MEIS2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE203158_5_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PBK	Pathway Commons Protein-Protein Interactions	1.0	null
UBE2I	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58814
Perturb_16523_KO_Ahr_SRP318414	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.51615
GTEX-QEL4-0008-SM-447AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
GSE175787_5_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TRIM35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01722
Perturb_16609_KO_Larp7_SRP189392	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.68113
OCILY19	CCLE Cell Line Gene Expression Profiles	1.0	1.3936
Prostate adenocarcinoma_PRAD_TCGA-YL-A8HO-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_1236_KD_RBMX_SRP033393	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.64762
Brain Lower Grade Glioma_LGG_TCGA-HT-A61B-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_1181_KD_CBFB_ERP128097	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.45112
DDX49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57867
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.365
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8110-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer II of piriform cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.905667
DGKD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0668
PNMA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95078
GSE247862,GSE247863_4_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-1286	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Sarcoma_SARC_TCGA-DX-A2J1-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anterior cingulate area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86708
cd8.Tcell	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Anchoring junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.233
RTCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94591
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE143782_3_v_4_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Microfibril	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.893
GSC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85319
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QV31-0008-SM-447AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4425
GSE77108_4_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.98805
BD-61-OO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.830291
GSE124410_3_v_5_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GA-88-CF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210834
renal	GeneRIF Biological Term Annotations	1.0	null
Pupal wing	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.956
GSE174383_1_v_5_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PIK3CG_knockdown_96_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.90055
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2024
PON2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8627
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE60217_1_v_8_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE85874_4_v_5_kdm5c_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
TPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65155
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-NPJ7-0008-SM-4E3JS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
TUBG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39878
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Integrin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.739
LRRC58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98184
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A83P-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QXCU-0008-SM-48FCH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59055
Artery - Aorta	GTEx Tissue Gene Expression Profiles 2023	1.0	1.31751
YBEY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6745
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A62N-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05141
H4K20me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE175787_5_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PYDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26057
Cell trailing edge	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.699
GSE146982_7_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PRPF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49453
MLYCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70589
GSE151612_4_v_2_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.076
C5orf34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44502
ECHS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13298
r4 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46217
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-5248-01A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CCNF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89472
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3473-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U8T8-0008-SM-4DXSP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
GSE211983_0_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE137137_1_v_0_rcor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DROSHA-22980978-HELA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7315-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.41491
Brain Lower Grade Glioma_LGG_TCGA-DU-5872-02A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4634137-ncomms9549-s7.xlsx-ZF_Hair_cell_data-Unnamed_1_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE181966_5_v_3_has2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X638-0008-SM-47JZ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
FLI1	ChEA Transcription Factor Targets	1.0	null
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07033
GTEX-QDT8-0011-R11A-SM-32PKD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90101
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18847
GSE127970_1_v_3_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
malignant glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.204593
LUC7L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24467
GSE211983_1_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hl60	HPA Cell Line Gene Expression Profiles	1.0	0.912143
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.33324
Superior olivary complex, periolivary region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15524
GSE210373_0_v_1_cntnap4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135030_11_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
NOP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43024
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15005
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_downregulated_genes-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.45414
NH12	DepMap CRISPR Gene Dependency	1.0	3.84595
pleural fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.2559
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968606
BRD4-27068464-CHIP-SEQ-AML-CELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
POMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39897
BD-73-TX58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.307857
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15512
ACSM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70848
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12137
GSE223893_11_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC10933434-44319_2024_69_MOESM2_ESM.xls-HRV16-UV_vs_MI-Associated_Gene_Name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4988-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KA-75-LP02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.72349
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLK10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35726
PALS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56303
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_downreg-mouse_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43S-01A-21R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-A53C-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885464
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.443
TFEC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.47
ZBTB12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1408
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TY-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE234637_1_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GATA1-19941827-MEL-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
BCLAF1	ENCODE Transcription Factor Targets	1.0	null
TIE1_knockdown_107_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.44079
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.7811
PRDM14-21183938-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTHRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39933
IRX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88158
CHMP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37451
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.63054
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.93116
GSE111385_2_v_1_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CIITA	ChEA Transcription Factor Targets	1.0	null
SA-37-YW78_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.209011
FGF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77437
PMC7889611-41467_2021_21346_MOESM10_ESM.xlsx-High_TSA_score_correlations-Supplementary_Data_6_Genes_with_expression_that_positively_correlate_with_a_high_TSA_score_in_AIRE_and_corneocyte-like_mTECs_AIRE	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1417	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-X4XY-0008-SM-46MVL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25089
CPSF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95285
GSE88819_6_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SKNAS	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3265
coronary artery disease	GWASdb SNP-Disease Associations	1.0	0.910724
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15481
UTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71788
GTEX-X3Y1-0626-SM-3P5YS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929632
ZNF395_02_69	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.72792
AASDHPPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5397
amygdaloid complex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3164
mediodorsal nucleus of thalamus_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.18749
SNAI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9338
FGFR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53269
HNRNPUL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00588
principal sensory nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1747
ChIP_TBX3_20139965	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
AC-84-QG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.226164
ALDOA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53639
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.226
H3K27ac_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ATP6V0E2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10357
LCLC-97TM1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC10492032-mmc1.pdf-1-BATF2_BATF2	Rummagene Transcription Factor Associations 2026	1.0	null
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.51899
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.29665
arisen	GeneRIF Biological Term Annotations	1.0	null
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.970321
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
CF-87-AS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.331133
GSE116354,GSE117379_3_v_5_cox2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
E2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0411
GSE221577_3_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
UD-07-US73_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.252528
GARIN5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33132
VSX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16148
remarkably	GeneRIF Biological Term Annotations	1.0	null
GSE168807_6_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
laminin-2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.833
Brain Lower Grade Glioma_LGG_TCGA-TM-A84F-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE147210_3_v_4_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OIZI-0005-SM-2XCED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23512
corneal disease	GWASdb SNP-Disease Associations	1.0	0.720957
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51H-06A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAB6D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27261
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88754
SP1_02_67	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.05889
PMC9170821-JCMM-26-3183-s001.xlsx-Mic_DAPI_ERG_VaD_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8379
SH3PXD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45031
GSE132948,GSE132949_4_v_3_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ventral tegmental area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.832307
HEC251	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77057
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.027
RYBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83938
GSE135350_3_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
amygdaloid complex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05992
periventricular stratum of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52475
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.87136
PNMA6F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74333
GSE77108_6_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
SOX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33137
Perturb_12961_KO_NMNAT1_SRP313669	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
AHCYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.347
COPS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00017
RPL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90445
Lung adenocarcinoma_LUAD_TCGA-91-6829-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.7592
HOPX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89516
dorsolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.33915
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RMI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41829
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.922125
mediodorsal nucleus of thalamus_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00494
Amnioserosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.991
GSE162084,GSE162085_2_v_6_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BD-49-MD69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.350184
abnormal peripheral nervous system morphology	GWASdb SNP-Phenotype Associations	1.0	0.381704
ZNF417	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7518
GSE196407_1_v_0_fluorouracil_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
VDAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98893
A4FUK	CCLE Cell Line Gene CNV Profiles	-1.0	-1.90431
AOB, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03288
TGFBR1_knockdown_102_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.8284
GSE183251_1_v_0_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55206
GSE212772_0_v_1_ncoa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mantle zone of IC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0897
GTEX-W5X1-0001-SM-3P61V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847752
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07674
supraoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34048
TUT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.04762
GTEX-QDT8-0006-SM-32PL3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09699
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01536	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.08881
ISY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56093
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5Q5-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central medullary reticular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.828149
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30668
GTEX-PLZ4-0008-SM-48TE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39571
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.86481
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
ZNF517	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32823
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AD-51-FB60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.433993
TIGD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28552
Urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.046
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.125
Calpain complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.534
ANKIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13298
Perturb_1736_OE_NHD13_SRP068420	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.53903
GSE214514_3_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64022
GP1BA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40299
GSE203158_0_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
outer CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16017
GSE171177,GSE171181_1_v_0_e7107_human	RummaGEO Drug Perturbation Signatures	-1.0	null
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.064393
leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056895
GSE114992,GSE114993_4_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6449
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventral tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2887
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HE-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CXCL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68224
GTEX-Q2AI-0008-SM-48U2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42209
PIK3C2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81232
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14855
GSE157960_2_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.2382
GTEX-U8XE-0005-SM-3DB8I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4171
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02725
METTL25B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17411
GSE152441,GSE152442_6_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE180200,GSE180201_3_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-SN8G-0008-SM-4DM4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
PMC11701299-EXCLI-23-1375-s-001.pdf-5-IKZF5_IKZF5	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QV31-0126-SM-447BP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8299
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A3F2-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area, mouth, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44602
Breast Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
SRSF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41528
ATF3_02_54	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.16993
GSE216147_0_v_1_rbm20_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GATA3-21867929-CD8-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
FB-66-UU47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.353458
Attachment organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.626
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE180200,GSE180201_5_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NFYA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68629
XRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67227
GSE162688_1_v_2_pink1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HMGN3_02_45	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.49185
Blood-macrophage	Tabula Sapiens Gene-Cell Associations	1.0	0.457841
H3C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23516
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894677
Respiratory system_CT1_cDC2 CD1c-positive myeloid dendritic cell	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
MEIS1	ChEA Transcription Factor Targets	1.0	null
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35757
periventricular stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55288
TIMM50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50593
KO52	CCLE Cell Line Gene Expression Profiles	1.0	1.57329
thymus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
ZMIZ1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB-20513432-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-T5JC-0626-SM-3NMA6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888152
ACTB	Hub Proteins Protein-Protein Interactions	1.0	null
U937	CCLE Cell Line Gene Expression Profiles	1.0	1.35416
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28391
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17303
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30788
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.3052
RVH421	CCLE Cell Line Gene CNV Profiles	1.0	1.93277
GSE68155_1_v_0_gpr3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CBLL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35388
ETV4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22415
anchoring junction	GO Cellular Component Annotations 2015	1.0	null
GTEX-U4B1-0008-SM-4DXUW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
GSE147943_2_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A band	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.924
episupraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69219
TCCSUP	CCLE Cell Line Gene Expression Profiles	-1.0	-2.15293
GC-04-UF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.310413
PMC4580636-pone.0138782.s005.xls-Sheet1-Table_S3_List_of_Genes_with_RUNX1_binding_sites_in_each_Cytogenetic_Group_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
vomeralnasalorgan.VMO.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.869053
GSE157960_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
STAT5A_02_72	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.08746
GSE210476_9_v_0_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE111247_14_v_12_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC3245917-supp_gkr685_nar-01129-x-2011-File015.xls-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05708
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-OXRN-2426-SM-2I5EQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.987219
PMC7468443-Data_Sheet_2.xlsx-DEG_6h_LPS-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE143643,GSE143644_2_v_0_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.97156
GSE144443_0_v_6_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE212312_2_v_3_fbxw7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular non-membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
PMC11522423-41598_2024_76982_MOESM1_ESM.pdf-27-THAP9-AS1_THAP9	Rummagene Transcription Factor Associations 2026	1.0	null
ATXN7L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91451
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.194
TEAD2_02_33	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.58496
Perturb_13050_KD_Gad1_SRP304099	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.7195
BBS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63317
Sarcoma_SARC_TCGA-RN-A68Q-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04585
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40595
amygdaloid complex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.940588
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Primary somatosensory area, mouth	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21119
GTEX-PLZ5-1726-SM-2I5F6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.83407
Lung adenocarcinoma_LUAD_TCGA-97-A4M2-01A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053516
r4 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30646
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5472
OSBPL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36246
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.133
EF-80-OD07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.233053
GSE239844_7_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE211983_1_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ini1hsnf5	GeneRIF Biological Term Annotations	1.0	null
GTEX-QVUS-0008-SM-447AY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35834
laminin-10 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.997
IC-05-AW29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.30852
GTEX-S4P3-0008-SM-3NM8R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11121
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
PIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68974
GTEX-NL3H-0008-SM-4E3HU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26456
HEY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2891
C32	CCLE Cell Line Gene CNV Profiles	1.0	1.42833
Natural killer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.558
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.50593
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.984719
Sarcoma_SARC_TCGA-DX-A3M2-01A-21R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUN	JASPAR Predicted Transcription Factor Targets	1.0	null
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.193
glia	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058375
KG1	CCLE Cell Line Gene Expression Profiles	1.0	1.48608
H3K27ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4698	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
GTEX-SNMC-1426-SM-2XCFM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00879
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6004
SUM225CWN	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.604205
GSE134191_2_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE184884_7_v_1_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
striatum_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.973687
GTEX-R55C-0008-SM-48FCF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40937
deep layers of olfactory entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.53639
GSE124410_3_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98701
DC-70-EK34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.516071
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.69795
r3 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60543
COCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE185519_1_v_5_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-0.875773
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32001
HCC89	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.904204
PFSK1	DepMap CRISPR Gene Dependency	1.0	2.01053
DUSP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95905
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
MARVELD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54548
cell-matrix adhesion	GO Biological Process Annotations 2015	1.0	null
GSE216043_3_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
r9 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49349
MST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3763
HDLM2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40436
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YN-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XQ3S-0008-SM-4GIDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28345
GSE134191_3_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NISCH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53228
posteroventral (inferior) parietal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.10533
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.891671
lymphnode_5c	HPA Tissue Sample Gene Expression Profiles	1.0	1.30708
LDB1_02_35	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.08746
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4672
H3K4me1_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ELK1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CPXCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95052
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05442
Lung squamous cell carcinoma_LUSC_TCGA-21-1076-01A-01R-0692-07,TCGA-21-1076-01A-02R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIRT6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146982_7_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE220520_6_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ES4	DepMap CRISPR Gene Dependency	1.0	2.25489
ZNF441	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1144
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0367
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30115
inner CP in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06275
GTEX-OXRK-1826-SM-2HMJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.824441
GTEX-XBEC-0008-SM-4AT3X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
GSE60217_1_v_9_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Integrin alpha2-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.082
H4C9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09653
GSE180200,GSE180201_15_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CNPY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42252
lateral ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.31
PDGFRA_knockdown_117_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.89025
Muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.027
GTEX-QDVN-0008-SM-48U2D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
PSMA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29567
abnormality of the vasculature	GWASdb SNP-Phenotype Associations	1.0	0.107063
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.362
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LL-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF384_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15701
spleen_3a	HPA Tissue Sample Gene Expression Profiles	1.0	0.92398
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_24_chimp_DRSG_higherRes-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.064618
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
TBX20-22080862-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28015
GTEX-T2IS-0526-SM-32QP9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04088
Posterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28617
GTEX-XV7Q-0005-SM-4BRWI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876021
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-DEG_MDDC_C91-PL_LPS_vs_MDDC_Jurkat_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
JC-06-ED36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.591534
cell projection membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.089644
GSE171837_3_v_1_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE94849_7_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
QE-79-XO29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.312448
TBX3-20139965-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
amygdaloid complex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.72501
COPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16866
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19O-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE242083,GSE242098_2_v_5_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99658
NADK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07369
SCAMP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.94537
r9 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55288
HELQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14634
A-VN-1203-2004(H5N1)_Day7-10^3pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.96683
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910515
GSE135030_3_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE235596_0_v_1_pikfyve_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
lateral part of MM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.26488
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3498
medial geniculate complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.29666
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.861028
TBX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1327
GSE246911,GSE246913_4_v_1_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE231720,GSE231724_2_v_0_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE151782_1_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041293
SINHCAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77418
Ventral premammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16459
IFIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15877
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Mesothelioma_MESO_TCGA-LK-A4O4-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857633
KIF3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65538
CTCF	ENCODE Transcription Factor Targets	1.0	null
GSE85874_4_v_1_kdm5c_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DROSHA	ChEA Transcription Factor Targets	1.0	null
urinary bladder	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PU.1-20513432-BCELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Polar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.552
primary motor-sensory cortex (samples)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.69777
MEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75961
PMC6065369-41467_2018_5367_MOESM9_ESM.xlsx-Table_6-Correlation_analysis_between_expression_of_ESR1_and_actin_regulators_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
MFN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29553
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AV-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4PP-1626-SM-2HMJF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.82767
Perturb_14443_KO_Mtor_SRP106322	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.61753
CDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55352
ZNF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54858
Integrin alphaIIb-beta3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.416
KAT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10686
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06777
GSE69244_1_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GOSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05725
CDCA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39502
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.2975
dementia	GWASdb SNP-Disease Associations	1.0	0.339425
Lymphoid tissue	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.288158
PMC5670203-41467_2017_1251_MOESM5_ESM.xlsx-differential_expressed_BCL6_tar-ensembl_gene_id_BCL6	Rummagene Transcription Factor Associations 2026	1.0	null
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.50593
H3K27ac_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EP300_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X88G-0008-SM-47JWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2467
GSE178255_5_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158815_5_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OE-31-YC41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.311712
FBXL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88016
OA-54-FL10_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.604732
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3573
ERBB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2685
PMC5731741__F3	PFOCR Pathway Figure Associations 2024	1.0	null
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC5670203-41467_2017_1251_MOESM5_ESM.xlsx-differential_expressed_BCL6_tar-gene_id_BCL6	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM184C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92719
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GK-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE60217_1_v_2_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.183
ASPRV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52734
Respiratory system_CT1_non-classical or patrolling monocyte	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_57_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
inferior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02365
external cortical nucleus of inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43456
r10 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74339
RUNX1	ChEA Transcription Factor Targets	1.0	null
rnf2_20805357_u2os_osteosarcoma_lof_human_gpl570_gse23035	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.606584
CCNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61385
Granular lamina of the cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0897
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21253
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.911369
LHX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04555
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE174735_4_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MT-ND6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93334
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
dorsolateral part of Lat	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6207
HCFC1	ENCODE Transcription Factor Targets	1.0	null
ARHGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5502
SIPA1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46538
GSE160817_2_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Anterior cingulate area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.57057
urinary system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HE-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6379-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE111247_14_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CCDC103	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5438
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.980125
TCF7-22412390-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.8725
PRDM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49608
superficial stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.60989
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JO-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4PQ-0008-SM-48TDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32996
Lung squamous cell carcinoma_LUSC_TCGA-85-8355-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE168807_0_v_8_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE94849_1_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE111247_11_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RPIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93882
WTAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.51871
b220.bcell	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
GSE174735_1_v_0_il22_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9906
GSE172189_0_v_1_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
OF-05-CB18_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.484036
NFATC1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.911426
JUND	ENCODE Transcription Factor Targets	1.0	null
CETN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00945
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.64501
GTEX-O5YU-0008-SM-4E3I7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13507
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937149
GSE171837_1_v_2_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE221577_1_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S4UY-0006-SM-3K2A7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02126
OSTM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41308
RFX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bone marrow	HPA Tissue Gene Expression Profiles	1.0	1.06267
PPARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4643
IRF4_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE88819_0_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE224096_3_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
cytoskeletal protein binding	GO Molecular Function Annotations 2015	1.0	null
HEV_60Day_None_GSE53731	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.07324
PMC5927328-NIHMS77085-supplement-Table_S4.xlsx-Table_S4A_LPS_induced_genes_GO-Unnamed_14_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Caco-2/15 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.737
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.88582
GSE207582_4_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Septate junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.984
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.258
LYSMD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90691
GTEX-QDT8-0008-SM-48U2F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09037
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE180200,GSE180201_5_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PWCY-0008-SM-48TE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10832
GTEX-U4B1-0526-SM-4DXTK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50441
COLO679	CCLE Cell Line Gene CNV Profiles	1.0	1.36833
GSE77108_3_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
ARHGEF6	Pathway Commons Protein-Protein Interactions	1.0	null
Sarcoma_SARC_TCGA-HS-A5N9-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE240896,GSE240899_5_v_4_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PW2O-0008-SM-48TEB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19941
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8004
MME	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75507
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RW-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE188458_2_v_1_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PNKD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53877
KIAA1671	Pathway Commons Protein-Protein Interactions	1.0	null
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.38751
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851777
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.21588
Survival in colon cancer	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.51549
SUM102PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.776211
GSE160817_3_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
mantle zone of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57188
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.838569
Lung squamous cell carcinoma_LUSC_TCGA-90-7767-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149943_2_v_3_cd8a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899787
GTEX-Q734-0008-SM-48U2I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19976
adherens junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.634159
Lung adenocarcinoma_LUAD_TCGA-55-6968-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE160817_2_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-A4M0-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TANGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83525
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19P-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE199921_1_v_0_romidepsin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Adrenocortical carcinoma_ACC_TCGA-P6-A5OG-01A-22R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ChIP_H3K27me3_17603471_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
amygdaloid complex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.61213
PMC5731741__F3	PFOCR Pathway Figure Associations 2023	1.0	null
TCF7-22412390-EML-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
FF-28-ES17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.291103
GSE209698_2_v_1_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08157
JHOM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.86483
GSE85874_3_v_1_kdm5c_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE114013,GSE114014_1_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
OAZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95715
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.976574
USP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86281
OCIAML3	CCLE Cell Line Gene Expression Profiles	1.0	1.767
IDO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67982
GSE100316_3_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.16428
central gray of the pons, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02931
CHD2	ENCODE Transcription Factor Targets	1.0	null
CAPAN1	DepMap CRISPR Gene Dependency	1.0	2.77925
Perturb_12817_KD_Stmn2_SRP148807	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.11338
PMC6977700-aging-12-102667-s006..xlsx-Sheet1-The_identified_1173_dysregulated_LmiRM-CTs_in_MI_using_our_method_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
KASUMI6	CCLE Cell Line Gene Expression Profiles	1.0	1.6806
SCYL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07263
GA-28-SS67_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.409626
GSE110178_1_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4375
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56465
GSE154767_1_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OXRL-0008-SM-3NB29	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25227
JE-04-LS32_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.580445
GTEX-QDT8-3026-SM-32PKB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.878736
HS 69ST	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.885298
PITX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86488
PMC9307901-mmc2.xlsx-S5-GATA6-AS1_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
CYTH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97257
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4771-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.84287
GTEX-RWS6-0008-SM-47JYV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08485
GTEX-X4XX-0008-SM-46MVK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39397
MOLM6	CCLE Cell Line Gene Expression Profiles	1.0	1.50435
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04718
HNF3A	MotifMap Predicted Transcription Factor Targets	1.0	null
HC-01-FD24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.469728
GSE231720,GSE231724_3_v_0_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10933434-44319_2024_69_MOESM2_ESM.xls-HRV16-UV_vs_MI-Ensembl_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
HO-1-U-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FB-66-UU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.525043
GSE133213_11_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
smooth muscle	HPA Tissue Protein Expression Profiles	-1.0	-1.14355
GSE110178_1_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S33H-0008-SM-4AD6C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39986
HSF1_02_73	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.49185
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7802
GTEX-U3ZG-0001-SM-47JYF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874947
SREBF1	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-XOTO-0008-SM-4GICE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53552
GSE155567_1_v_0_cd33_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Primary somatosensory area, upper limb, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85447
GSE148510_1_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cerebralcortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.15136
CCND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87272
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Intrinsic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.212
GSE94849_3_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Rectum adenocarcinoma_READ_TCGA-AH-6643-11A-01R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4847-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GOT1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77042
MZ in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.69824
GTEX-R53T-1826-SM-3GIJX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.999346
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.931992
SNU886	CCLE Cell Line Gene Expression Profiles	-1.0	-2.72246
retina	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.10565
GTEX-XMK1-0126-SM-4B65F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52908
PMC4221415__F5	PFOCR Pathway Figure Associations 2024	1.0	null
GSE174498,GSE174500_3_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GB-06-BA49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.624578
GSE110178_5_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-K1-A6RV-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052869
RUNX1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1541
PMC9171028-Table2.XLS-Supplementary_material_2-SP100_SP100	Rummagene Transcription Factor Associations 2026	1.0	null
GSE171837_0_v_2_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RU72-0008-SM-46MV8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23661
GSE120612_6_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ADAM17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1056
Kindler syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.33
GTEX-WFG7-0008-SM-4LMKB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40857
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20769
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.309928
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02016
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053238
Contractile actin filament bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.845
precentral gyrus, right, inferior lateral aspect of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.46428
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93325
BMF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94798
A253	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE131425_2_v_3_arg2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OOBK-0008-SM-3NB27	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57206
C15orf62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66801
PMC10933434-44319_2024_69_MOESM1_ESM.xls-HRV16_vs_MI-Ensembl_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
FKBP15	Pathway Commons Protein-Protein Interactions	1.0	null
GATA1	ChEA Transcription Factor Targets	1.0	null
MT1X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.73076
FUBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10576
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.8428
EXOC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05015
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.2438
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047326
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
SPI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
20502458-TableS6a	GeneSigDB Published Gene Signatures	1.0	null
PANC0504	DepMap CRISPR Gene Dependency	1.0	8.01638
superficial stratum of r4BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30685
496100455_FWM_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.55087
FRS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5715
GTEX-SJXC-0008-SM-4DM7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.49223
C1QL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17539
GSE146074_0_v_11_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate stratum of IC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14142
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
RARA_KD_GDS4065_42_human_MCF-7	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.861236
gata1_15860665_megakaryocytes_lof_mouse_gpl1261_gds1245	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.048956
WC-09-GD62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.343883
PMC12634441-41375_2025_2771_MOESM8_ESM.xlsx-ATACseq-Table_S3_Bulk_ATAC-seq_GATA2_vs_control_Only_p-adj_0_05_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-OOBJ-1626-SM-2I3F7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.996551
TBX3-20139965-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-S7PM-0008-SM-3NM9Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09468
AQP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68371
TSC22D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.70989
focal adhesion	KEGG Pathways	1.0	null
HNRNPM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44762
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.44463
GSE173232_2_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4431	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Brain Lower Grade Glioma_LGG_TCGA-CS-6665-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6625
GTEX-Q2AH-0226-SM-48U1I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28958
SKGT2	DepMap CRISPR Gene Dependency	1.0	4.91341
PMC11148097-41698_2024_569_MOESM2_ESM.pdf-196-BCL11A_BCL11A	Rummagene Transcription Factor Associations 2026	1.0	null
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ACAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06862
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
intracellular membraneless organelle	GO Cellular Component Annotations 2025	1.0	null
hematopoietic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055711
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.289582
GTEX-WHSE-0926-SM-3NMBS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.886831
hsa-miR-378g	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Lung	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE166004_5_v_4_pld1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE162688_3_v_2_pink1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
share	GeneRIF Biological Term Annotations	1.0	null
PMC4823830-ncomms11171-s3.xlsx-high_in_shRNA_GATA3-GeneSymbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TMZS-0008-SM-47JWM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
GTEX-N7MS-0008-SM-4E3JI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
amygdaloid complex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.952606
GTPBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31355
ChIP_REST_18959480	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
hsa-miR-125a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
posterior (caudal) superior temporal cortex (area 22c)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.936501
ERBB2_druginhibition_7_GDS2139	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.59544
GTEX-Q734-0626-SM-2I3EF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852282
GSE148692,GSE148695_2_v_6_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5113908-pone.0166185.s004.xlsx-Supp_1-Supplementary_Table_1_mRNA_expression_correlates_with_STAT3_phosphorylation_for_1279_genes_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5081-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXM1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
X	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.47789
GSE226584,GSE226589_1_v_0_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3TX-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM86B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53277
MPRIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38063
Sarcoma_SARC_TCGA-3B-A9HO-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.927325
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15044
GSE206729_2_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MNT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5727
NFATC2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58713
Integrin alpha7-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.14
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01848
STRN4	Pathway Commons Protein-Protein Interactions	1.0	null
RABEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46545
NCIH211	DepMap CRISPR Gene Dependency	1.0	2.0347
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CUX1	ENCODE Transcription Factor Targets	1.0	null
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61372
GSE148692,GSE148695_1_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FAM216A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95011
SPI1	ChEA Transcription Factor Targets	1.0	null
GSE169152_5_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
spleen_3d	HPA Tissue Sample Gene Expression Profiles	1.0	1.13041
RARA-24833708-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
spleen	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE88819_0_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE238018_3_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PWOO-0726-SM-2I3EB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833303
YIPF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02575
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4798-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE190322,GSE190324_3_v_4_rbm4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEG4-0008-SM-48TYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE131798,GSE131804_1_v_0_igf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80834
GSE230656_0_v_1_gsdmd_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.354
primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.967633
PD-05-HV36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.40078
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.46106
u-937 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.377996
cell projection organization	GO Biological Process Annotations 2023	1.0	null
lung	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053175
Respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874943
superficial stratum of isBI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10592
COLO678	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77484
Focal adhesion	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A94Y-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gracile nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02471
PGBD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1514
GSE227891_5_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
actin cytoskeleton reorganization	GO Biological Process Annotations 2015	1.0	null
DF-75-OU25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.574823
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A6HP-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central gray of the pons, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03541
GSE129811_5_v_0_niacin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE184884_6_v_5_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KCL-22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4173-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYCN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.766
LONP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35848
superficial stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4626
M band	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.996
Podosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.215
GSE85874_3_v_5_kdm5c_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE127790_6_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.870339
GSE180200,GSE180201_12_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MRPL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71636
REC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51282
CACNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86941
TSPYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39278
NCIH1092	CCLE Cell Line Gene CNV Profiles	-1.0	-2.78553
GNL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51225
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42879
spleen_3c	HPA Tissue Sample Gene Expression Profiles	1.0	1.00948
ventrolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.46111
H3K27ac_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83T-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE169152_3_v_7_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE138938_1_v_4_foxp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GADD45A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72031
GTEX-RU72-0011-R7A-SM-2TF5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846958
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4697-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-V9-A7HT-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE111247_14_v_10_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7786291-Table_1.xlsx-Table_S1-Supplementary_table_1_ETV7-related_genes_in_the_TCGA_SKCM_data_set_ETV7	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XAJ8-0126-SM-47JYG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52569
Folium-tuber vermis (VII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.76885
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.126433
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
GSE223008_0_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE126463_6_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
laterodorsal tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00443
GTEX-XPT6-0008-SM-4B64Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07406
GSE144231_4_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23265
substrate adhesion-dependent cell spreading	GO Biological Process Annotations 2025	1.0	null
TLE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72953
vascular disease	GWASdb SNP-Disease Associations	1.0	0.092564
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.88453
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040093
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.829491
GTEX-XOT4-1426-SM-4B65T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914496
GSE135030_3_v_1_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE136233,GSE136234_0_v_1_zpbp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE120612_4_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LOUCY	CCLE Cell Line Gene Expression Profiles	1.0	1.46733
GTEX-SE5C-0008-SM-4B64J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55885
Tenocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.879
MYB-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.224
cell leading edge	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.18516
GE-53-SM76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.691635
LIM1215	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
schizophrenia	GWASdb SNP-Phenotype Associations	1.0	0.43573
retromammillary area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59281
GTEX-W5X1-0006-SM-3GIJZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57113
Primary somatosensory area, unassigned, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06845
SIN3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59345
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
lymphoid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071369
GSE147662_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Ebolavirus(ZEBOV)_3day_Spleen_None_GSE57214	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.58584
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
USP53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31585
GSE211177,GSE211178_9_v_3_ets1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6619
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ELK3_ELK3	Rummagene Transcription Factor Associations 2026	1.0	null
SMIM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78483
GTEX-SJXC-0526-SM-2XCFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00729
TXNIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36776
GSE199255,GSE199356_6_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AC-74-ZA35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.612
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.922125
GSE182181_1_v_0_ricolinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE169155_5_v_4_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC5095001-oncotarget-07-36293-s002.xlsx-Table_S2-Table_S2_MYCN-correlated_genes_and_their_correlations_with_other_transcription_factors_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
Posterolateral visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58008
GHITM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49951
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30077
Prostate adenocarcinoma_PRAD_TCGA-VP-A87C-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97155
VCX3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7785
Perturb_11900_KO_Irf8_SRP265303	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
AML193	CCLE Cell Line Gene Expression Profiles	1.0	1.43468
NOC3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01611
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LA-42-ER00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.320761
GSE159728,GSE159730_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SERPINB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89918
639V	DepMap CRISPR Gene Dependency	1.0	4.21576
GSE228894_3_v_2_rnmt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
periventricular stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1267
GRHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4222
GSE203060_0_v_1_kdm4c_human	RummaGEO Gene Perturbation Signatures	1.0	null
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27758
DA-20-VR86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203816
RBBP5	ENCODE Transcription Factor Targets	1.0	null
OTULIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99736
SP in perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.858313
LARP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12734
GTEx AdrenalGland 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	1.0	3.19324
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NFK9-1026-SM-2HMK1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859383
PMC9288051-13046_2022_2428_MOESM4_ESM.xlsx-Super_enhancers_in_AML2-OVERLAP_GENES_RUNX3	Rummagene Transcription Factor Associations 2026	1.0	null
PPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92715
BA-56-QV45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20255
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.21911
SNW1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33929
GSE144231_4_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A4/FUK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.72127
CE-18-AP15_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.612919
CUL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51862
GTEX-NL3G-0008-SM-4E3JX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
primary motor-sensory cortex (samples)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.878839
thp1	HPA Cell Line Gene Expression Profiles	1.0	0.969264
lm1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.763
GSE145639_1_v_2_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE123022,GSE123030_2_v_0_trem2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE182179_0_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC70	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48043
ovary_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.06454
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUR-01A-21R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CSRNP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3094
UBR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47445
APP	Pathway Commons Protein-Protein Interactions	1.0	null
MAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62474
internal granular layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17819
mammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88035
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02349
ARID3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33191
LARP4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48534
NUP133	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35876
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_downregulated_genes-Unnamed_6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
RP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1202
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	1.0	0.90136
GATA1-19941827-MEL-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877016
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
VZ in midcingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.60154
GB-57-XV52_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.262332
Pancreas-myeloid cell	Tabula Sapiens Gene-Cell Associations	1.0	2.78326
Hmx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.5272
GSE191174_0_v_1_ccdc92_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE224969,GSE224971_0_v_1_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
substrate adhesion-dependent cell spreading	GO Biological Process Annotations 2023	1.0	null
GSE151829,GSE151831_1_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DPCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88457
Cortical microtubule cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.577
EJM	CCLE Cell Line Gene CNV Profiles	-1.0	-2.70771
paracentral lobule, anterior part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.2663
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.847465
r5 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65115
exocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060744
GSE166294_0_v_1_etv5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CEBPB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE255680_1_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Malignant exocrine pancreas neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.13732
SMRT-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-2V-A95S-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE226091,GSE226092_0_v_1_sall1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
STX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84735
GYG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83873
periventricular stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01418
ME-31-RM40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220799
GSE214725_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
LRP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19588
FADU	CCLE Cell Line Gene CNV Profiles	1.0	2.48621
SRY-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37613
YA-92-YO01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.300206
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.47155
layer 1 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1747
GTEX-WYVS-0006-SM-3NMA7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61162
MBD3L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80658
JHH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.863321
SMARCA4_02_47	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.24793
COLO849	CCLE Cell Line Gene CNV Profiles	1.0	1.63828
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3123
PMC4072629__F3	PFOCR Pathway Figure Associations 2023	1.0	null
PMC6977700-aging-12-102667-s004..xlsx-Stage1-The_identified_3126_dysregulated_LmiRM-CTs_in_stage_1_of_MI_1_day_of_MI_using_our_method_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
morphological abnormality of the central nervous system	GWASdb SNP-Phenotype Associations	1.0	0.071177
oligodendroglioma	GeneRIF Biological Term Annotations	1.0	null
DNAJC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73808
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
lm5	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.212
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.28363
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7590-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
19218430-TableS3	GeneSigDB Published Gene Signatures	1.0	null
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
DICER1_Deficiency_GDS3685_518_mouse_Hepatocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Cellulose synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.682
Lung adenocarcinoma_LUAD_TCGA-55-6985-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE178255_2_v_0_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Myelin membrane	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.855
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.03716
PMC6080909-JEM_20171312_TableS1.xlsx-Each_THP1_Pulldown_Expt_Targets-Unnamed_1_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
Sarcoma_SARC_TCGA-QQ-A8VG-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE125219,GSE125221_4_v_8_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
Costamere	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.84
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.0596
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13825
GSE116492,GSE116495_3_v_2_stag2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE178255_3_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FGFR1OP2	Pathway Commons Protein-Protein Interactions	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
KIAA2013	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30919
PMC5577301-in-17-237-s001.xls-AR_upregulated_DEGs-Liver_GSE13440_GENE_AR	Rummagene Transcription Factor Associations 2026	1.0	null
2-iminoacetate synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.688
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1881
GSE166920_6_v_4_adalimumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE210476_9_v_4_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE201309_5_v_6_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
OC-10-FB51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200658
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_24_macaque_DRSG_lowerRes-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RTLS-0008-SM-48FET	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39418
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05065
TRIM28	ChEA Transcription Factor Targets	1.0	null
GTEX-U3ZH-1926-SM-4DXTR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.9354
GTEX-VUSG-0008-SM-4KL24	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22596
DROSHA-22980978-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
artery disease	GWASdb SNP-Disease Associations	1.0	0.128567
QA-07-KC40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.404753
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.39983
EMC-BAC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08435
intermediate periretromammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04417
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.62461
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5ED-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LITAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78608
HCC1171	CCLE Cell Line Gene Expression Profiles	-1.0	-1.85384
CLEC14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36309
GTEX-S341-0008-SM-4AD6D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21813
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.857774
salivary gland carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.304684
GSE158715_2_v_4_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FAM156B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02947
GTEX-V1D1-0826-SM-3P5ZA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14868
KB-78-BE93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.233985
PPP1R15A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33463
RPS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12909
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97852
PMC5740757__F4	PFOCR Pathway Figure Associations 2024	1.0	null
EN2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9909
coronary artery stenosis	GWASdb SNP-Phenotype Associations	1.0	0.800972
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.832805
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
REXO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70702
Kidney renal papillary cell carcinoma_KIRP_TCGA-KV-A6GD-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
Integrin alphaD-beta2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.992
spinal cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056274
SYMPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75388
THP1	CCLE Cell Line Gene Expression Profiles	1.0	2.06807
Primary somatosensory area, lower limb, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32306
NR2C2_02_77	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.9386
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.847321
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.079467
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A1A1-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10492032-mmc2.pdf-11-BATF2_BATF2	Rummagene Transcription Factor Associations 2026	1.0	null
NR3C1	ENCODE Transcription Factor Targets	1.0	null
GF1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
layer 4 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05922
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE148321,GSE169423_2_v_1_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE166920_6_v_1_adalimumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE147210_3_v_5_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
superficial stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20874
rostral group of intralaminar nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.58245
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_24_chimp_DRSG_higherRes-Hg_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.970321
MOB4	Pathway Commons Protein-Protein Interactions	1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE223008_6_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EIF5AL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60724
ZC3H12C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.782
deep layers of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.47138
striatum_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13389
PMC3677161__F5	PFOCR Pathway Figure Associations 2024	1.0	null
superficial stratum of r3BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60435
Pancreatic adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.903319
CCDC28B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02859
GTEX-WHPG-2226-SM-3NMBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.89289
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.872651
Integrin alpha6-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.928
PMC6684323-NIHMS1532201-supplement-Table_S6.xlsx-LPS-Sup_Table_6C_Delta_PVE_among_PopDE_genes_LPS_PopDE_FDR_0_2_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE110440_1_v_0_rad21_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TLR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28835
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.96245
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044612
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11143
Liver hepatocellular carcinoma_LIHC_TCGA-GJ-A3OU-01A-31R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE100316_0_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_1169_KD_CBFB_ERP128097	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.076
ZSWIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60299
PMC8190596-mmc2.xlsx-ETV6_mut-ETV6_mut_ETV6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-W5X1-0008-SM-4LMKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08649
Prostate adenocarcinoma_PRAD_TCGA-KK-A8I4-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE199204,GSE211619_4_v_6_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE215086_5_v_0_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
parolfactory gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.60794
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.40217
EBF1	ENCODE Transcription Factor Targets	1.0	null
GPRIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5653
GTEX-XXEK-0126-SM-4BRVU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61028
FC-85-OX77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.216386
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE117042_1_v_3_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RHOB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92174
Sarcoma_SARC_TCGA-3B-A9HJ-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAB8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82526
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.182
CRLS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7971
19192944-TableS4	GeneSigDB Published Gene Signatures	1.0	null
hsa-miR-3131	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A4BA-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Respiratory system_CT1_effector memory CD4-positive, alpha-beta T cell	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
GTEX-OIZH-0926-SM-48TBR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8241
APC	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF737	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84174
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02249
urinary tract	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ZXDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3455
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IJ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DC-43-KF54_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.23792
GTEX-WOFM-0126-SM-3MJFE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878846
Integrin alphav-beta3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.471
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	50.1795
MAPKAPK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6722
interpeduncular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.939925
GTEX-WK11-0526-SM-3NB3O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845809
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A7UA-06A-32R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZDHHC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00998
GTEX-RNOR-0008-SM-48FEY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61156
RNF138	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96814
18160665-TableS5	GeneSigDB Published Gene Signatures	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2832-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4656	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Primary motor area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45081
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7501
MEIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8522
ASB16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58364
cytoskeleton	GO Cellular Component Annotations 2015	1.0	null
OSBPL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5914
GSE112714_2_v_3_ctnnb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RPE1SS6	DepMap CRISPR Gene Dependency	1.0	2.38035
Uterine Carcinosarcoma_UCS_TCGA-ND-A4WF-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE255680_2_v_0_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_16419_Mut_Gli2_SRP154383	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.65123
GATA1-19941827-MEL86-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
EGR1	ENCODE Transcription Factor Targets	1.0	null
CORO2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23119
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828048
DD-74-PJ26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.12758
organization	GeneRIF Biological Term Annotations	1.0	null
GTEX-SIU8-0008-SM-4BRUC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44814
CERCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31329
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.4115
GSE133213_10_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEx AdrenalGland 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	4.74535
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.13959
DDHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67607
primary motor cortex (area M1, area 4)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06878
GSE195513_2_v_1_cpeb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CDK16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62033
LCLC103H	CCLE Cell Line Gene CNV Profiles	-1.0	-2.24125
posterior (caudal) superior temporal cortex (area 22c)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04908
PBX1	ChEA Transcription Factor Targets	1.0	null
GSE201309_4_v_7_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.35
TMEM140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27842
APELA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35762
GRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41109
orbital frontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.995815
GSE217201_1_v_0_asap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
20460173-ImmPortComprehensiveListofImmune-RelatedGenes	GeneSigDB Published Gene Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-YA-A8S7-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-11A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XBEW-0008-SM-4AT3Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
LENG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37492
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4341
GSE166920_6_v_2_adalimumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_17400_KD_HMGCR_SRP216293	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.12371
GSE126463_5_v_3_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ABRAXAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12141
Perturb_1787_KO_Irf8_SRP265303	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
KLHL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33318
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11216
striatum_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.20563
NKX2-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17575
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978651
MTA3	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A6I3-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77601
H3K27me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-OXRL-1626-SM-2YUMU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.992675
GCLM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49046
NYAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.54851
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01424
HES6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4754
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19641
seem	GeneRIF Biological Term Annotations	1.0	null
PMC9541747-AGE-53-680-s003.xlsx-TableS6-Table_S6_Genes_with_missense_mutations_in_Yaroslavl_cattle_MAF_0_1_and_FST_0_4_in_the_1000_Bull_Genomes_Run_9_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
actin cytoskeleton	GO Cellular Component Annotations 2023	1.0	null
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995705
GSE58724_1_v_4_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CREG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56124
GSE221577_4_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GATA2_02_28	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.2854
PMC10363146-41598_2023_38681_MOESM1_ESM.pdf-427-PRRX1_PRRX1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10123531-NIHMS1874945-supplement-Table_S6.xlsx-SOX2_BCAT_cobound_peaks-Gene_Name_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
UTP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31829
fusiform gyrus, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.54067
dorsolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13386
GTEX-PX3G-0008-SM-48U2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24543
GSE185519_4_v_7_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S95S-0008-SM-4AT5M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
Hepatitis C virus genotype 1b (isolate Con1)	Virus MINT Protein-Virus Interactions	1.0	null
GSE116810_5_v_1_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PIWIL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29146
FAM174C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46042
H3K9ac_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-30c-5p	MiRTarBase microRNA Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4354-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NAGPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1724
Focal adhesion	WikiPathways Pathways 2024	1.0	null
hsa-miR-491-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
likely	GeneRIF Biological Term Annotations	1.0	null
PMC8567138-Table_2.xlsx-Sheet1-IGFBP5_AND_IGFBP7_NOT_IGFBP3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
parasubicular cortex (parasubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.950914
NOMO1	CCLE Cell Line Gene Expression Profiles	1.0	2.48933
GSE202434,GSE202438_7_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-O5YV-0008-SM-4E3HP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63866
GTEX-XK95-0008-SM-4AT5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13337
GTEX-SNOS-1526-SM-32PLW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838972
Actin cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.25
SIN3A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARHGEF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19592
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54G-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
actin cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.291787
adherens junction	GO Cellular Component Annotations 2015	1.0	null
GTEX-RVPU-0011-R10A-SM-2XCAH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.894138
USP17L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78783
GTEX-X88G-0004-SM-47JZ6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85736
Pontine gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20693
GRM	CCLE Cell Line Gene Expression Profiles	-1.0	-1.72631
GTEX-T2IS-2626-SM-32QPP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01184
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.36123
CEBPB	ENCODE Transcription Factor Targets	1.0	null
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.35606
GSE175787_4_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K23me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE168458_1_v_3_disulfiram_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
WDR59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40088
critically	GeneRIF Biological Term Annotations	1.0	null
actin binding	GO Molecular Function Annotations 2023	1.0	null
ARV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35579
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30788
GSE239688_4_v_0_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RINT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90885
GSE129389_0_v_4_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.862578
VWCE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84492
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE199204,GSE211619_4_v_0_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC6870463-Table_7.xlsx-Family_H_No_LPS-Untreated_BMDMs_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
JUND	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59694
GSE141726,GSE141733_1_v_0_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PML	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OIZG-1326-SM-2HMIQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03229
PPM1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89321
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.77388
SRY-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-RUSQ-0126-SM-47JWV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19367
TCL1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35353
INCENP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57197
hematopoietic system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
DGCR6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84243
RVH421SKINFV1	DepMap CRISPR Gene Dependency	1.0	3.89331
Anterior cingulate area, dorsal part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09599
DMAC2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3978
22RV1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OS-01A-12R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
spleen	HPA Tissue Gene Expression Profiles	1.0	1.13866
KIAA1143	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43794
SKBR3	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.05752
GSE169152_3_v_2_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CDK5_knockdown_99_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.76295
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965678
HEPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55673
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27403
NSA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25395
TBC1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49683
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.964516
MAPK1IP1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53552
GTEX-TKQ1-0008-SM-4DXSO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20617
orbital frontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.952604
GTEX-S3XE-0008-SM-3NM8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54675
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.027
eye and adnexa disease	GWASdb SNP-Disease Associations	1.0	0.119467
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06377
Pancreatic adenocarcinoma_PAAD_TCGA-Q3-A5QY-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AB-09-EA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.586362
ZD-85-ND87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24716
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.871844
SOCS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80192
BC-54-ON71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.505887
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895188
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.826461
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
pleura	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.1927
GPX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53711
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4QT-0008-SM-48TDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45135
GTEX-R55G-0226-SM-48FEI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22611
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
primary visual cortex (striate cortex, area V1/17)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.69677
Cell leading edge	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.646
MYH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16761
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE70935_2_v_4_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BD-49-MD69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.476826
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE160817_4_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CUX1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCKAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98288
Acute Myeloid Leukemia_LAML_TCGA-AB-2920-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUYS-0005-SM-47JZ2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53964
GTEX-T5JW-0008-SM-4DM5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98525
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0