association	dataset	threshold value	standardized value
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08481
GTEX-U3ZM-0008-SM-4DXTQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56247
Mesothelioma_MESO_TCGA-TS-A7P8-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OC316	DepMap CRISPR Gene Dependency	1.0	8.99906
MTF2-20144788-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE173911,GSE173917_0_v_1_morc3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE225869_3_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
17555561-Table2	GeneSigDB Published Gene Signatures	1.0	null
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05526
cerebellar white matter	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28161
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GT-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T5JW-0003-SM-3NMAD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09019
GSE235066_4_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J9-A52E-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Carbamazepin-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U0-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE179531_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
A2058	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Adenoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.752
REST_PFSK-1_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF_Q1_vs_Q4-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF7L2_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_PHC1_16625203	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_MYOD1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
PMC3636213-pgen.1003459.s012.xlsx-Sheet1-KD_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12499388-ADVS-12-e01774-s002.xlsx-Table_S1-Table_S1_Differentially_Expressed_Genes_between_wild-type_and_TET3-knockout_PANC-1_cells_TET3	Rummagene Transcription Factor Associations 2026	1.0	null
midbrain reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.33028
GSE102505_1_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8224457-MSB-17-e9760-s005.xlsx-C_Ctrl_v_HMGB1-KD_IMR90-Gene_AR	Rummagene Transcription Factor Associations 2026	1.0	null
orbital frontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.935697
superficial stratum of r4Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69652
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03472
Perturb_5768_KO_Sip1/Nkx21_SRP010804	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context1_2-Nearest_Ensembl_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE166315_2_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
17724462-TableS1	GeneSigDB Published Gene Signatures	1.0	null
GSE205070_2_v_7_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_14110_OE_C11orf53/Pou2f3_SRP343255	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.18319
mantle zone of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49845
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE94814_1_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135030_3_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-MethylMerc-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
NFYB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PK59	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4622
hsa-miR-3177-5p	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
CMK115	DepMap CRISPR Gene Dependency	1.0	4.31329
POLR2A_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane	GO Cellular Component Annotations 2015	1.0	null
GTEX-S4P3-0008-SM-3NM8R	GTEx Tissue Sample Gene Expression Profiles	1.0	3.15593
preweaning lethality, incomplete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
GSE195559_6_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE226439,GSE226441_6_v_2_hnf4g_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202825_2_v_1_ano1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6939-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40971
Perturb_5323_KD_Hif1a_SRP386119	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
BT16	DepMap CRISPR Gene Dependency	1.0	2.47179
GSE233679_6_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_CD19 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE228181_0_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01385
desmosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.284401
mRNA_GATA3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.544152
GSE151090_5_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE239844_4_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE229671,GSE229673_2_v_1_yrdc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
lmx1b_18351676_hind_limb_bud_lof_mouse_gpl1261_gds3320	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.271
Fastigial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1494
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VH-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE172016_2_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QV31-0008-SM-447AT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57098
CTCF_WI38_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040609
Bed nuclei of the stria terminalis, posterior division, interfascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71186
cerebellar cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.24165
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.98242
Prostate adenocarcinoma_PRAD_TCGA-HC-7752-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.957945
CAL 27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41668
CTCF_epithelial cell of proximal tubule_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10489
GSE213588_8_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
r3 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26498
PMC12661646-dmm-18-052290-TableS6.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	1.72779
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09433
Inflammation	CTD Gene-Disease Associations	1.0	1.28518
H3K27me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ALG13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0516
GSE203308_4_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE119978,GSE180930_6_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE225900_1_v_0_hsdl2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE221742,GSE221743_1_v_2_sipa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.974536
MDH1	Pathway Commons Protein-Protein Interactions	1.0	null
CCND1-20090754-RETINA-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE233679_5_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
placenta_6c	HPA Tissue Sample Gene Expression Profiles	1.0	0.960187
H3K4me3_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SCL-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A3JM-01A-12R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE214382,GSE214383_5_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
JUN	ENCODE Transcription Factor Targets	1.0	null
SW1990	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52535
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.293
Brain_CT2_CGE 284	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
PTPN1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830769
KAT14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05884
Paraventricular hypothalamic nucleus, parvicellular division, medial parvicellular part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22422
GSE205070_2_v_9_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-CA-geneName_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF-_SURVIVAL-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.89771
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41515
GSE229978_4_v_1_morphine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF143_02_59	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.80735
GSE142210_9_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3HZ-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U9-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE233679_12_v_13_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S4UY-0008-SM-3NM8H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05434
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57217
Mebendazole_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0203354
Male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.047
mRNA_MSC_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE216043_11_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.29103
PCDH18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83308
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_3_SED-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21173
zfx_17448993_embryonic_stem_cell_lof_mouse_gpl1261_gds2718	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.170685
PMC9585487-NIHMS1838959-supplement-4.xlsx-Downregulated-Table_S3_FOXC1_regulated_genes_FOXC1	Rummagene Transcription Factor Associations 2026	1.0	null
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9232687-13238_2021_887_MOESM3_ESM.xlsx-37_KD_sgCDC20_vs_sgNTC-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22075
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OQ-11A-21R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hyperactivity	MGI Mouse Phenotype Associations 2023	1.0	null
Connective tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PMC5414054-ncomms15013-s11.xlsx-SupplementaryData10-Supplementary_Data_10_Genes_differentially_expressed_due_to_infection_in_IRF5-_-_compared_to_parent_KOLF2_cells_IRF5	Rummagene Transcription Factor Associations 2026	1.0	null
Dorsal lip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.58
primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.22793
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE216043_7_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.35676
BRK1	Pathway Commons Protein-Protein Interactions	1.0	null
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.944826
GTEX-XPT6-0008-SM-4B64Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37365
Perturb_8481_KD_DAP5_SRP073613	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-14.2806
GSE120612_7_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
TC32	DepMap CRISPR Gene Dependency	1.0	5.87285
superficial stratum of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18538
biological_process	GO Biological Process Annotations 2015	1.0	null
blood	GTEx Tissue Gene Expression Profiles	-1.0	-2.10021
FGFR1HighNME5- epithelial cell_Esophagus_Human	CellMarker Gene-Cell Type Associations	1.0	null
GSE210655_3_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
periventricular stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05627
H3K9me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-2578-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_foreskin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE133087_5_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
superficial stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31976
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
hsa-miR-182	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13569
lymphnode_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.90904
GSE233679_12_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Superior colliculus, motor related, deep white layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62291
Perturb_9250_KO_Rgnef_SRP185891	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	15.7981
Perturb_8760_KO|KD_LATS1/LATS2|MK5_SRP222878	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
mantle zone of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.92399
CACFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12511
BFTC-909	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.960476
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5B-Up_H3K4me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4264	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GTEX-T2IS-0011-R11A-SM-32QPC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857758
GSE171401_1_v_0_adnp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216757_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8325-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anatomical structure development	GO Biological Process Annotations 2015	1.0	null
bj	HPA Cell Line Gene Expression Profiles	1.0	0.870527
ATF3-23680149-GBM1-GSC-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TBX22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1137
GSE173201_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Infigratinib_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0120019
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00893
kidney	HPA Tissue Protein Expression Profiles	-1.0	-0.721964
GSE140651,GSE140653_2_v_7_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE186223,GSE186224_6_v_3_hmces_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
medial superior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03367
CORL24	CCLE Cell Line Gene Expression Profiles	-1.0	-2.04677
mRNA_EOMES_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Paraventricular hypothalamic nucleus, parvicellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62037
GSE100102_2_v_5_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
Perturb_13185_Mut_Cry2_SRP303502	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.731
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02768
GSE160817_5_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BL6028 (WDR20)	NURSA Protein Complexes	1.0	null
GTEX-T5JW-2026-SM-4DM63	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82589
GTEX-WYJK-0005-SM-3NMA1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836821
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Desmosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.251
GTEX-OIZI-0005-SM-2XCED	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00233
cerebral cortex	HPA Tissue Protein Expression Profiles	-1.0	-1.87787
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE217694_3_v_0_pold1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7149-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_5139_KD_Dax1/Dux_SRP311833	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.88271
MZ2-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Sulfisoxazole_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0194398
TAF1	ENCODE Transcription Factor Targets	1.0	null
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.974536
Cadherin conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.134
c4i	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.544
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940739
17963910-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18573
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5177-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.946362
GSE144796_1_v_0_linagliptin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-73-7498-01A-12R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.41743
GTEX-NFK9-0008-SM-4E3JE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2661
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3433-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE232631_0_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.935592
stratum lacunosum-moleculare of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03352
GSE147626_3_v_1_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33111
CEBPD-23245923-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.947714
mRNA_MYC_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
hippocampus (hippocampal formation)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00739
GTEX-R55E-0006-SM-2TC5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.964027
Perturb_13875_KO_LIN28B_SRP335506	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.5255
JEKO1	CCLE Cell Line Gene CNV Profiles	1.0	2.25556
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20788
GTEX-RWS6-0001-SM-3NMAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887255
microcephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.595233
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.60008
USF1	ENCODE Transcription Factor Targets	1.0	null
hatching gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.41583
GSE186065_0_v_1_sirt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7566571-supp_075176.120_Supplemental_Tables.xlsx-Supplemental_Table_S9-Down_in_MSC_chond_2_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE111247_2_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE186707_1_v_0_hdac4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
pharynx	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.401765
GSE96641_5_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Lithium_Chloride-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
GSE203131_0_v_1_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
vitamin c_homo sapiens_gpl6884_gse16590	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZNF566	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39785
Perturb_8941_Mut_RB1_SRP220467	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-14.8466
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4345-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IPO13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12234
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
LOU-NH91	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.66307
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Pimozide_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0222566
solitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04705
GSE128333_4_v_5_tcf4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_3662_KD_RBM26_SRP243927	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.831516
dorsolateral part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58283
GTEX-XPT6-0001-SM-4B64G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30492
GSE134412_0_v_1_siah2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Uterus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.05156
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901946
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20R-11A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreas	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PMC8561673-NIHMS1742950-supplement-Table_S7.xlsx-Housekeeping_MYC_ProxTubGenes-Proximal_Tubule_Enriched_Genes_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S3XE-0526-SM-4AD4G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.829568
PMC7566571-supp_075176.120_Supplemental_Tables.xlsx-Supplemental_Table_S9-Down_in_OE_HAC_and_Down_in_MSC_chond_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE225982_1_v_0_ezetimibe_human	RummaGEO Drug Perturbation Signatures	-1.0	null
caudal division of IPC (area 39)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.828367
GSE210682_2_v_1_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE154074_2_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28875
corneal opacity	MGI Mouse Phenotype Associations 2023	1.0	null
GSE120612_4_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE137325_3_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
cingulate gyrus, retrosplenial part, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03206
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4538	TargetScan Predicted Conserved microRNA Targets	1.0	0.389112
HOXD8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5381
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.855548
PMC10243915-uxad037_suppl_supplementary_table_s1b-table_s3b.pdf-97-SETDB2_SETDB2	Rummagene Transcription Factor Associations 2026	1.0	null
Cortical amygdalar area, posterior part, lateral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25548
LN-229	COSMIC Cell Line Gene Mutation Profiles	1.0	null
glia	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.137762
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
r2 part of superior vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81026
GSE184356_3_v_0_tfam_human	RummaGEO Gene Perturbation Signatures	1.0	null
PFSK1	DepMap CRISPR Gene Dependency	1.0	3.95348
Dorsal peduncular area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14742
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.998152
hallux	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.03214
CEBPD-21427703-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE131588,GSE131690_1_v_0_setd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	3.06658
GSE174701_4_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
RIDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06752
developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.158097
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CCND1	ChEA Transcription Factor Targets	1.0	null
GSE165647_2_v_3_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Squamous Cell Carcinoma Of The Head And Neck	DisGeNET Gene-Disease Associations	1.0	null
Perturb_6447_OE|KD_EGFR|TRIM24_SRP100743	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE185944_2_v_4_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PRADC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32698
LOUNH91	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48821
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.690687
hsa-miR-4796-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GSE242199_9_v_7_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
WDR73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21094
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27715
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Vismodegib_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0284289
shortened QT interval	MGI Mouse Phenotype Associations 2023	1.0	null
TE9	CCLE Cell Line Gene CNV Profiles	1.0	2.0737
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.35647
liver	HPA Tissue Protein Expression Profiles	-1.0	-1.87787
Sclerotome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.86
PMC12621392-12864_2025_12212_MOESM2_ESM.xlsx-GSF-S_48h_1-Unnamed_0_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context1_2-Gene_Name_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.46857
PMC10123531-NIHMS1874945-supplement-Table_S3.xlsx-SOX17_BCAT_cobound_coreg_peaks-Gene_Name_SOX17	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02802
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7391-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE240386,GSE242143_1_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8895
Microcephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.323
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-SOX4_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.125
SKLMS1	CCLE Cell Line Gene CNV Profiles	1.0	1.41292
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.912865
EP300	ENCODE Transcription Factor Targets	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5K9-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCND1-20090754-RETINA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
intermediate stratum of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60279
GSE198165,GSE198166_0_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
outer CP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06072
Interventricular septum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.839
POLR2A	ENCODE Transcription Factor Targets	1.0	null
CHK1_KD_GSE54267_672_human_U2OS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
periventricular stratum of PPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36458
NB5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary motor cortex (area M1, area 4)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1575
DAOY	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53532
second (ventral) preoptic domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13859
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
Perturb_16648_KO_Tardbp_SRP201975	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.40824
hsa-miR-543	TargetScan Predicted Conserved microRNA Targets	1.0	0.085563
lymphnode_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.2366
Acute Myeloid Leukemia_LAML_TCGA-AB-2882-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
estradiol_homo sapiens_gpl6947_gse27375	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE217405_0_v_1_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Dentate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13029
PMC9377669-tx1c00392_si_002.xlsx-Favipiravir-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
STX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05155
SCS214	DepMap CRISPR Gene Dependency	1.0	2.12169
NFIC_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E8-11A-12R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE112358,GSE112359_0_v_1_med23_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE128730_4_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE119978,GSE180930_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
pyramidal layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.47751
GTEX-QVJO-0008-SM-447AU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37732
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XK95-0008-SM-4AT5G	GTEx Tissue Sample Gene Expression Profiles	1.0	2.25878
Prostate adenocarcinoma_PRAD_TCGA-YL-A8HO-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11003700-pbio.3002240.s013.xlsx-siMYCN_RNA_IMR32_48h_q_0_05_1_5-Table_S6_Genes_commonly_and_differentially_regulated_by_MYCN_and_WDR5_in_IMR32_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4261	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
CTCF_fibroblast of pulmonary artery_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
GTEX-R3RS-0008-SM-48FF1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17128
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXF1_FOXF1	Rummagene Transcription Factor Associations 2026	1.0	null
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.84498
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01669
GSE213588_10_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Refractive error	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.0301
hsa-miR-4672	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
GSE93309_2_v_0_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7376-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of TG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14902
SHP77	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3658
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060155
GSE233647_4_v_5_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Olanzapine_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0249636
hsa-miR-4289	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
GSE214823,GSE214824_6_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TAF7L_KO_GDS2857_556_mouse_ES cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01639
GSE151090_0_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain_CT2_Inh L1 LAMP5 NMBR	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7123-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.81463
layer II of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.893009
GSE231720,GSE231724_3_v_1_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_13869_KO_LIN28B_SRP284310	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.47681
PMC9377669-tx1c00392_si_002.xlsx-Doxylamine-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
RERF-LC-SQ1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Developmental and epileptic encephalopathy 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.704
TCF12_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.00576
COR-L88	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WFJO-1926-SM-3GILA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00289
GTEX-OHPM-0008-SM-4E3IP	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02638
NCI-H2803	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03472
GTEX-WYVS-1726-SM-3NMAY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870375
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
corpus callosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.853788
schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.1936
Bicalutamide_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0256993
GSE130956_0_v_3_icaritin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Nearest_Ensembl_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
NANOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55749
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.839215
Prostate adenocarcinoma_PRAD_TCGA-EJ-7783-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
CTCF_choroid plexus epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
forelimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.165482
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.51594
GSE232836_2_v_6_morphine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Integral component of the cytoplasmic side of the plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.22
PMC12629827-mmc8.xlsx-DDR2_KD-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TRIM28	ENCODE Transcription Factor Targets	1.0	null
PPARG-20887899-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HS578T	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.900054
GSE150349_0_v_1_msx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-R55F-1726-SM-2TF4R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849332
GSE115363_2_v_0_esrrb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.859363
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.942376
GTEX-OXRK-0008-SM-3NB28	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33032
mRNA_NRIP1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Internal female genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4280	TargetScan Predicted Conserved microRNA Targets	1.0	0.103424
17660535-TableS4c	GeneSigDB Published Gene Signatures	1.0	null
hsa-miR-550a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GSE168458_1_v_3_disulfiram_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Heart - Atrial Appendage	GTEx Tissue Gene Expression Profiles 2023	1.0	1.2293
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.15024
GSE156923_2_v_1_rbmx_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE123689_1_v_0_cbx8_human	RummaGEO Gene Perturbation Signatures	1.0	null
Internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.047
BMI1	ChEA Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BX-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adult body size	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.65229
Prenatal Injuries	CTD Gene-Disease Associations	1.0	1.34285
GSE126463_4_v_2_arid2_human	RummaGEO Gene Perturbation Signatures	1.0	null
retrotrapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16805
decreased body size	MPO Gene-Phenotype Associations	1.0	null
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_PSc_vs_NB_2D_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE223008_0_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.2806
PMC10123531-NIHMS1874945-supplement-Table_S7.xlsx-SOX17_BCAT_4TCFKO_peaks-Gene_Name_SOX17	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.977277
Perturb_5571_KO_RELA_SRP149723	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.27771
GSE233679_14_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.943747
GSE149760_0_v_5_elof1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_keratinocyte_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-4A-A93W-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KML1	DepMap CRISPR Gene Dependency	1.0	3.2482
DOK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072272
GSE137818_2_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151090_2_v_1_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intermediate stratum of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13753
Perturb_8482_KD_DAP5_SRP073613	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE142210_9_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
upper (rostral) rhombic lip_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.77121
GTEX-X585-0008-SM-46MU4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66556
GSE80098,GSE80366_0_v_6_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Heart septal defect	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.055
Esmolol (hydrochloride)_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0189993
GTEX-XOT4-0008-SM-4B664	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54893
GSE184892_7_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
vestibular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.284253
PMC9169777-pnas.2120787119.sd07.xlsx-Sheet1-Dataset_S7_Significantly_differentially_expressed_genes_between_G2_and_GATA3_WT_T-ALL_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
21205295-TableS1	GeneSigDB Published Gene Signatures	1.0	null
ZNF578	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4758
GTEX-TKQ2-1826-SM-33HB2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994147
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213153_1_v_0_ulixertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE258991_5_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE185944_2_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EBC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_2088_OE_APTX_SRP174572	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Heart disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.541
GTEX-UPK5-1826-SM-3GAEB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913263
GSE178714_5_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lhx8	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	13.3532
PMC10111863-supp_gad.350269.122_Supplemental_Paun350269_FileS3.xlsx-A_ASCL1-regulated_DGE-geneID_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_5588_KO_RELA_SRP149723	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
PMC5749531-jci-128-96551-s002.xlsx-Mouse_SPOP_Human_ERG-Hgene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
GSE174498,GSE174500_2_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CCDC174	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.35117
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20582
GSE158743_1_v_2_nfkbia_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5716
GSE148066,GSE157787_11_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FER	Pathway Commons Protein-Protein Interactions	1.0	null
ARID1A_01_345	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.68131
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10489
mantle zone of r2Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81333
CEBPB-21427703-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE221327_4_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
MZ in dorsomedial parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10353
GSE89767_1_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Neurobehavioral Manifestations	CTD Gene-Disease Associations	1.0	1.20751
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08563
hsa-miR-137	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
hsa-miR-3679-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GSE193351_1_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7328-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Relugolix_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0256883
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mRNA_FEM1B_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
CNN3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE142210_9_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.398357
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-TCF21_TCF21	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
vemurafenib_homo sapiens_gpl6244_gse24862	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XLM4-0008-SM-4AT4W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72539
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IGHA1	Pathway Commons Protein-Protein Interactions	1.0	null
Posaconazole_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0230319
GSE214823,GSE214824_4_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10489
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28096
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MW-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE221327_4_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
SUZ12	ChEA Transcription Factor Targets	1.0	null
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS821T	CCLE Cell Line Gene Expression Profiles	1.0	1.41769
GSE103003_1_v_0_zeb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
periventricular stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33329
TAL1-26923725-CHIP-SEQ-HEMANGIOBLAST-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.8269
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZH-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FV-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00526
GSE108675_3_v_0_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135030_8_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.25899
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01948
Prostate gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.047
r2 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29616
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE225869_1_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ERBB3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE175787_5_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Bone Marrow Diseases	CTD Gene-Disease Associations	1.0	1.09506
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
endometrium_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.06875
Perturb_158_KD_Prmt1_SRP360688	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.2208
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10489
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Essential hypertension (time to event)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.739794
mRNA_ASCL1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
JURLMK1	CCLE Cell Line Gene CNV Profiles	1.0	1.55814
r3 part of parvicellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12031
GSE142210_11_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.061097
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7485
Tetracycline (hydrochloride)_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0250248
glial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.130242
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.89316
PATU8902	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51572
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21525
GSE147366_1_v_4_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10489
intermediate stratum of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02717
colliculus superior	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16426
GTEX-N7MS-2526-SM-2D7W3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860513
lateral spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32393
ATF3-23680149-GBM1-GSC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Perturb_339_KD_EIF4A1_SRP072285	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.03939
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Palatine tonsil_CT1_tonsil squamous cell	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE184892_7_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OCIMY5	CCLE Cell Line Gene CNV Profiles	1.0	2.59961
Ovarian Neoplasms	CTD Gene-Disease Associations	1.0	1.05274
GTEX-W5X1-0001-SM-3P61V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.95212
Perturb_11684_KD_NCAPH2_SRP157799	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.54472
GSE219274,GSE219276_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE142210_11_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE188870,GSE188871_0_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205163,GSE205164_2_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cadherin	InterPro Predicted Protein Domain Annotations	1.0	null
hippocampus (hippocampal formation)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45495
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.17497
Mafg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.9151
GSE216538_0_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-516b	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61201
GSE125153_1_v_0_bcl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211128_4_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_13182_Mut_Cry2_SRP303502	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.14891
Torkinib_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0464302
GTEX-QMR6-0008-SM-447AV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34525
SUZ12-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-4420	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
PMC7857731-elife-63093-supp5.xlsx-ECMdegs-pB-MITF-FLAGvs_pB-FLAG-Unnamed_4_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XV7Q-0008-SM-4BRWL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1397
RAD21_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_ZSCAN4C_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
PMC12621392-12864_2025_12212_MOESM2_ESM.xlsx-GSF-F_48h_1-Unnamed_0_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_fibroblast of mammary gland_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ2-0004-SM-3NMAC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21113
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10489
GTEX-T6MN-0002-SM-3NMAH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46458
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cochlea	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.317315
GTEX-RU72-0008-SM-46MV8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19884
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0781
DUSP1_Deficiency_GDS1606_765_mouse_Spleen	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
r1 part of vestibulocerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52947
PMC9377669-tx1c00392_si_002.xlsx-L-Thyronine-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.47596
GSE238018_1_v_2_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_5570_KO_NFKBIA_SRP149723	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.02811
RBM4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13383
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE211151_1_v_4_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SW1463	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain stem	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE48812_0_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
amygdaloid complex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.851142
H3K27me3_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10305740-pwac061_suppl_supplementary_table_s1.xlsx-FOXO3-knockout_bulk_RNA-seq-Differentially_expressed_genes_identified_in_bulk_RNA-seq_of_FOXO3-_-_vs_FOXO3_hMyotubes_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142210_2_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE193258,GSE193259_9_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.0058
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6ZZ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-642b	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
PGR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.689
HLF	CCLE Cell Line Gene CNV Profiles	1.0	1.75076
PMC11196642-41419_2024_6838_MOESM5_ESM.xlsx-Supplementary_Table_3-Supplementary_Table_3_Differentially_expressed_genes_in_RNA-seq_between_MCF7_SMAD4-KO_and_parental_groups_SMAD4	Rummagene Transcription Factor Associations 2026	1.0	null
SKM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.83694
RNF2-18974828-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
cisplatin_mus musculus_gpl339_gds3099	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE214823,GSE214824_5_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055538
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE89018_6_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.942335
GTEX-R55E-0008-SM-48FCG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24592
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.92207
Lung squamous cell carcinoma_LUSC_TCGA-33-4533-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Weight Gain	CTD Gene-Disease Associations	1.0	1.03641
dactinomycin_homo sapiens_gpl7172_gse12459	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23984
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
THOC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89238
amygdaloid complex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16942
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7393-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
root	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.096762
Brain Lower Grade Glioma_LGG_TCGA-HT-8011-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_8942_KO_RB1_SRP220467	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.8018
GSE135030_3_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
paraventricular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.99103
GSE157894_2_v_0_cystine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cerebellum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-GATA4_GATA4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7566571-supp_075176.120_Supplemental_Tables.xlsx-Supplemental_Table_S9-DOWN_in_MSC_chondrogenesis_420_1_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Smith-Magenis syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
glioblastoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.702717
Colon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-466	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
Perturb_11624_KD_DUSP11_SRP113334	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.32708
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12119
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28832
Lung squamous cell carcinoma_LUSC_TCGA-56-6545-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
No annotation - 2	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
amygdaloid complex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.66635
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05129
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11294
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5875-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28304
GSE121319_1_v_2_gprc5a_human	RummaGEO Gene Perturbation Signatures	1.0	null
amygdaloid complex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.945922
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35874
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hallux	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.826
GTEx Nerve 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	-1.0	-6.83219
GSE213588_8_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
ChIP_EZH2_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GSE128730_4_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE142210_3_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
macroglia	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.165658
GSE202434,GSE202438_9_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10120965-pwac038_suppl_supplementary_table_s4.xlsx-siFOXP1-2_vs_siNC-Differentially_Expressed_Genes_DEGs_in_hCMs_upon_Silence_of_FOXP1_FOXP1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WFJO-0002-SM-3P61X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35671
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.13316
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.976765
PMC4387713-supp_gad.255984.114_Table_S4.xlsx-S4B-Up_Nanog_KD-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE138633_2_v_0_bag3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148066,GSE157787_8_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11784
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.49607
Kidney renal papillary cell carcinoma_KIRP_TCGA-4A-A93Y-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CJUN-26792858-CHIP-SEQ-BT549-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PK-59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09433
lower (caudal) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02073
GSE121319_1_v_0_gprc5a_human	RummaGEO Gene Perturbation Signatures	1.0	null
RARRES1_KD_GDS4818_314_human_SUM149	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-WQUQ-0006-SM-3MJF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21993
CTCF_cardiac muscle cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SE-0008-SM-33HB1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94737
Perturb_5030_KO_4930500J02Rik_SRP072189	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.00225
GSE233679_14_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BHY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CYFIP1	Pathway Commons Protein-Protein Interactions	1.0	null
Tectum mesencephali	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.887
midbrain raphe nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04394
GSE198165,GSE198166_5_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AR-22383394-PROSTATE-CANCER-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SNU-283	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.897267
U-CH2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Mesothelioma_MESO_TCGA-MQ-A4LP-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STK36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06862
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AG-2826-SM-2HMJQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.83339
central nervous system development	GO Biological Process Annotations 2025	1.0	null
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_downregulated_genes-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7330-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EC-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_4708_KD_Dnmt3b_SRP069225	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.17739
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7653
mantle zone of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13942
GSE95685_2_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Other source	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	4.617
GSE213588_8_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9862
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Body size at age 10	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.922185
UTP14C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02377
PMC7566571-supp_075176.120_Supplemental_Tables.xlsx-Supplemental_Table_S9-DOWN_in_MSC_chondrogenesis_420_2_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
CCN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27517
PMC9170110-pgen.1010161.s047.xlsx-DBP_DEP-nearestGene_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854434
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5012
GSE213588_9_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
brain cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.161754
GSE154074_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
496100396_HIP_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02142
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05113
GTEX-POYW-0726-SM-2XCEO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12154
frontal pole, right, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.838273
GSE178714_1_v_4_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SOX9	ChEA Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.058539
GSE174701_1_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
AR-22383394-PROSTATE_CANCER-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10489
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
pancreas_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.894039
GSE102505_6_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01009
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4165364-13059_2014_406_MOESM5_ESM.xls-Supp_Dataset_1-SUPPLEMENTARY_DATASET_1_AML3_AzaC_SigDiff_1147_Note_to_reviewers_-_view_these_files_as_xls_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PWCY-0008-SM-48TE9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36681
H3K4me1_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE217873_1_v_2_nusap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE160765_2_v_1_twist1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_6636_KO_SATB1_ERP024525	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GTEX-SUCS-0002-SM-3NMAJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22781
Riluzole hydrochloride_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0217949
EOL1	CCLE Cell Line Gene CNV Profiles	1.0	1.38602
EWS-26573619-CHIP-SEQ-HEK293-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.076927
GSE180185_4_v_8_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_EC_CSc_vs_NB_2D_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE171269_1_v_4_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
mediodorsal nucleus of thalamus_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0215
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12541
Adrenocortical carcinoma_ACC_TCGA-OR-A5KZ-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-2.02223
EGFR	Pathway Commons Protein-Protein Interactions	1.0	null
GSE235587_2_v_1_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CCFSTTG1	CCLE Cell Line Gene Expression Profiles	1.0	1.53921
GSE228181_3_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TKQ1-0008-SM-4DXSO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06953
LMSU	CCLE Cell Line Gene CNV Profiles	1.0	1.80953
PMC6932815-ppat.1007634.s015.xlsx-ST5_DGE_ELF1-R8AvIFN48-mock_lfc-external_gene_name_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4272	TargetScan Predicted Conserved microRNA Targets	1.0	0.293524
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE166169_0_v_3_elp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE116492,GSE116495_3_v_2_stag2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.355942
J82	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_2859_Mut_BRAF_SRP404927	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.743
H3K4me1_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02242
GTEX-VJYA-0001-SM-3NMDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.891887
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7923-01A-12R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE211128_2_v_1_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Temperament	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
urinary bladder	HPA Tissue Protein Expression Profiles	-1.0	-0.721964
PMC10201771-12864_2023_9385_MOESM1_ESM.xlsx-ST18-Unnamed_11_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TML8-2026-SM-32QOP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992959
Perturb_4198_KO_Fmr1_SRP075646	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.37793
GSE202434,GSE202438_8_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QEG4-0008-SM-48TYZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23604
GTEX-RWSA-0008-SM-47JYX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967322
GSE140997_10_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T5JC-2326-SM-32PMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885226
PEER cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.734
Cdc42 GTPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.94
terminal nucleus of the stria medullaris	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.61328
outer CP in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.61259
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0251
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10489
Lymphoid tissue	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE184892_6_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE155830_1_v_0_fkbp5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.25966
496100466_PCx_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.26124
hsa-miR-548p	TargetScan Predicted Conserved microRNA Targets	1.0	0.241055
PMC12540438-Data_Sheet_1.PDF-20-ENSG00000189164_ZNF527	Rummagene Transcription Factor Associations 2026	1.0	null
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30962
hsa-miR-135b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
ATF3	ChEA Transcription Factor Targets	1.0	null
hydrocortisone_homo sapiens_keloid scar_gds3071	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE198165,GSE198166_9_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r2 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31976
MAPK14_KD_GDS2693_533_mouse_A431	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
cerebellar cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.35226
KARPAS-299 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.91
nucleotide-excision repair factor 3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.578
RBBP5	ENCODE Transcription Factor Targets	1.0	null
GSE174498,GSE174500_2_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE205163,GSE205164_1_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-5_5-Diphenylhydantoin-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
superficial layers of olfactory entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02781
Liver hepatocellular carcinoma_LIHC_TCGA-HP-A5N0-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_8911_KO_YAP1_SRP132362	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-16.5795
NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.185016
CTCF_fibroblast of the aortic adventitia_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_STAT3_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
NFI-21473784-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
r5 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43693
GTEX-S7SE-0005-SM-2XCEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14413
GSE154219_0_v_2_cholestyramine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-4680-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Anterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51415
physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.478289
short tibia	MGI Mouse Phenotype Associations 2023	1.0	null
PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Differentially_expressed_genes_identified_in_bulk_RNA-seq_of_FOXO1-_-_vs_FOXO1_hMSCs_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE193258,GSE193259_2_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
periventricular stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28055
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
CLPP_KO_GDS4791_537_mouse_testis	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE136622_0_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE96641_3_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_6965_KO_MFng_SRP057171	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.56475
GSE130396_8_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-8_DEGs_RUNX1-OE_vs_control-Gene_Symbol_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-O5YW-0008-SM-4E3IE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6425
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10489
PMC11758349-11130_2024_1262_MOESM1_ESM.docx-4-RFXDC2_RFX7	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10489
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
alimentary canal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HOXB8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4818
GTEX-Q2AG-0008-SM-48U2K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11354
GSE142210_3_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Paraventricular hypothalamic nucleus, magnocellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.338
GSE205976,GSE205978_3_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
REST_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lymphoma_burkitts(Daudi)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.999725
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.40453
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX5_OE_GDS4978_548_human_L428-PAX5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
LN319	DepMap CRISPR Gene Dependency	1.0	2.22615
ventrolateral prefrontal cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.4147
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10489
Acute Myeloid Leukemia_LAML_TCGA-AB-2987-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10592962-media-4.xlsx-OC2_genes-gene_ONECUT2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XMK1-0008-SM-4GICF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54077
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33462
UACC893	DepMap CRISPR Gene Dependency	1.0	3.89673
GSE149359_2_v_0_asap2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6611
GSE211262,GSE211263_0_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.401
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Abnormalities, Multiple	CTD Gene-Disease Associations	1.0	1.1403
CHK2_KD_GSE54268_667_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE127916_1_v_2_nras_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02467
GSE135030_8_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
STAT3	ChEA Transcription Factor Targets	1.0	null
CTCF_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
occipito-temporal gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.978482
cetuximab_homo sapiens_gpl570_gse21483	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CP in retrosplenial cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.881539
rnf2_20805357_u2os_osteosarcoma_lof_human_gpl570_gse23035	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.459393
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.912865
c-Myc_OE_GDS3321_157_mouse_lung adenocarcinomas alveolar epithelia	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE205070_2_v_5_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intermediate stratum of r2Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81333
Gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE202434,GSE202438_3_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-V1D1-0003-SM-3NMDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52131
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RPL30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55468
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3559
GSE226355,GSE226357_1_v_0_ybx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE132369,GSE132371_1_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	1.0	null
Auditory vesicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.19
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15
Brain Lower Grade Glioma_LGG_TCGA-DU-5847-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral hypothalamic area, mammillary region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00738
GSE98705_1_v_0_mdm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.50914
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27419
hsa-miR-4465	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
astrocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.177671
GSE151829,GSE151831_3_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bisoprolol (hemifumarate)_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0137845
Metencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-XMK1-2226-SM-4B673	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06678
layer IIIu of area 35r	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.77656
CTCF_fibroblast of mammary gland_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE158815_1_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CSNK2A1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE233679_6_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Epstein-Barr virus copy number in lymphoblastoid cell lines	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.6
retina	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.31354
19621087-Table1d	GeneSigDB Published Gene Signatures	1.0	null
SIN3A_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5ED-11A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE207728,GSE207808_2_v_1_c646_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE205070_1_v_4_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH1355	CCLE Cell Line Gene CNV Profiles	1.0	1.39668
inferolateral temporal cortex (area TEv, area 20)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.868401
PMC5798892-41421_2017_3_MOESM9_ESM.xlsx-CARGs-MSC-Supplementary_Table_4_Gene_list_for_IARGs_and_CARGs_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE111247_14_v_3_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
AZ521	CCLE Cell Line Gene Expression Profiles	1.0	2.67735
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GATA2_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE139016_3_v_2_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE233679_5_v_9_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE195663_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_13890_KD_BRCA1_SRP135799	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-14.9113
lateral hypothalamic area, tuberal region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.836908
19356222-SuppTable6	GeneSigDB Published Gene Signatures	1.0	null
PHB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44215
GSE233647_2_v_3_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
r6 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05277
GSE224742_0_v_1_slc1a5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GNL3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60619
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE242199_9_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_6169_KD_PROX1_SRP073100	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.42877
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF_D1_vs_D10-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T6MN-0008-SM-4DM7H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75544
GSE226249_2_v_6_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XGQ4-0008-SM-4AT3Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36499
Perturb_15037_KD_Eif2ak3_SRP201230	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.87171
PMC4531812-13058_2015_618_MOESM11_ESM.xlsx-TCGA_Sparse_KM-TFAP2B_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
ETC-206_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0344714
DKMG	CCLE Cell Line Gene Expression Profiles	1.0	1.49784
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IQ-01A-31R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-9-cis_retinoic_acid-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal body composition	MPO Gene-Phenotype Associations	1.0	null
GSE200673,GSE200691_2_v_0_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CREB5_CREB5	Rummagene Transcription Factor Associations 2026	1.0	null
HS675T	CCLE Cell Line Gene Expression Profiles	1.0	2.11492
IGR-37	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTNND1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE226249_5_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06072
brain development	GO Biological Process Annotations 2015	1.0	null
Lateral reticular nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0477
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE213650_3_v_1_everolimus_human	RummaGEO Drug Perturbation Signatures	-1.0	null
deep white layer of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56867
GTEX-NPJ8-0226-SM-48TBN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829569
Intrinsic component of the cytoplasmic side of the plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.13
decreased total body fat amount	IMPC Knockout Mouse Phenotypes	1.0	null
GSE202434,GSE202438_9_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE111247_2_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC3708595-NIHMS474972-supplement-1.pdf-8-MYB_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Decreased_in_both_CSDE1_KD_hESC-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.74983
EP300_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_11618_KD_CEBPB_SRP113334	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.52117
PMC9509360-41419_2022_5262_MOESM6_ESM.xlsx-Fig_2D_MSC_targeted_RNF4-Down_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE216043_3_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC38	CCLE Cell Line Gene CNV Profiles	1.0	1.49868
GSE183606_1_v_0_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HOXB7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8093
Perturb_550_KD_EWSR1FLI1_SRP273158	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.4052
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18274
GSE127205_1_v_0_asf1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE224004,GSE224005_0_v_1_chd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
r3 part of vestibular sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.92221
PMC4904359-12915_2016_267_MOESM12_ESM.xlsx-LEUTX_DOWN-All_significantly_up_regulated_genes_determined_by_DESeq2_fold_change_greater_than_1_25_going_down_from_an_FPKM_of_at_least_2_LEUTX	Rummagene Transcription Factor Associations 2026	1.0	null
RPL38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48575
ATG5	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-144	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
GSE217115_3_v_0_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE210101,GSE210114_8_v_9_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135352_0_v_4_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17767
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14197
Medication use (agents acting on the renin-angiotensin system)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.839794
GTEX-R55D-0008-SM-48FEV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1485
GTEX-WVLH-0226-SM-3MJG6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937571
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5689-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.0422
ventrolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.37912
SNAP47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2827
CL-34	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.15434
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.97034
ARNT-22903824-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
P wave terminal force	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.852288
H3K27ac_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE217405_3_v_2_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211983_1_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SGCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02734
H1-10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03907
GTEX-X88G-0008-SM-47JWN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14195
GSE64642_0_v_1_sirt6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.937985
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.36933
GSE129858,GSE129859_1_v_3_robo1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.1094
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MALME3M	DepMap CRISPR Gene Dependency	1.0	2.30059
hsa-miR-579	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GSE210101,GSE210114_2_v_9_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4789-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NB-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Rectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE180185_4_v_5_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE160304,GSE163392_0_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE242199_6_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A66S-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Atherosclerosis	CTD Gene-Disease Associations	1.0	1.34547
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059116
GSE142232,GSE142234_0_v_2_gcgr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XPVG-0008-SM-4GICH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22413
GSE158182_4_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE102486,GSE102490_1_v_5_setdb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
C19orf53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01554
GTEX-UJHI-1426-SM-3DB9C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830603
BUB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.7334
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11663
GSE135030_3_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-QDT8-0626-SM-48TYW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0827
Mesothelioma_MESO_TCGA-LK-A4NW-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anastrozole_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0400607
Kidney Chromophobe_KICH_TCGA-KM-8442-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE225869_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE180185_9_v_8_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210383_0_v_1_trim71_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SMC3-22415368-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7794-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE139966_4_v_3_figla_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148321,GSE169423_2_v_1_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung Neoplasms	CTD Gene-Disease Associations	1.0	1.26021
GTEX-TMZS-0001-SM-3P61Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69497
Perturb_14247_KO_FOXM1_SRP328179	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.14288
Superior colliculus, motor related, intermediate white layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47019
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1	ENCODE Transcription Factor Targets	1.0	null
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75245
Spinocerebellar ataxia type 18	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.249
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5797
CHAGOK1	CCLE Cell Line Gene CNV Profiles	1.0	1.58962
congenital nervous system abnormality	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.476772
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE157383_6_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE191037_0_v_1_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE114690_1_v_3_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
REL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0588
RXYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17324
HDDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25082
Perturb_2633_KD_RCF31_SRP302775	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
RAD21	ENCODE Transcription Factor Targets	1.0	null
GSE101537_1_v_3_neurog3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_Symbol_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.831516
AR	ChEA Transcription Factor Targets	1.0	null
Liver_CT1_portal fibroblast	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
GSE113734_1_v_0_qprt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Oviduct	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Copper levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.51549
OCILY3	CCLE Cell Line Gene CNV Profiles	1.0	2.19205
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PMC12621392-12864_2025_12212_MOESM2_ESM.xlsx-GSF-S_48h_2-up-regulated_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PW2O-0008-SM-48TEB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71136
H3K79me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H4K5ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SCLY	ChEA Transcription Factor Targets	1.0	null
HES5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30496
GSE164757,GSE164759_1_v_3_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
striatum_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.58807
GSE232631_5_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE144500_7_v_6_ventx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.54105
Anterior hypothalamic nucleus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.96204
SOX2	ChEA Transcription Factor Targets	1.0	null
GSE178255_1_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_HCT116_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-889	TargetScan Predicted Conserved microRNA Targets	1.0	0.265648
Oleic acid_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0208836
GSE153137,GSE153140_2_v_1_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_16810_KD_Setd7_SRP075653	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE242199_2_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE184087_2_v_1_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE196318_0_v_1_xpo4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19995
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
cell-cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.068046
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.1341
Acute Myeloid Leukemia_LAML_TCGA-AB-2992-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7SF-0001-SM-3K2BE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06221
GSE198794_0_v_3_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE155836,GSE155839_3_v_2_alvocidib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216043_11_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1032
supramammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.12262
GTEX-RNOR-0008-SM-48FEY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21024
GSE206516,GSE206518_3_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE134896_0_v_3_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12224929-ADVS-12-2416784-s006.xlsx-DEG_circGLIS3_KD-Unnamed_6_AR	Rummagene Transcription Factor Associations 2026	1.0	null
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.6215
Perturb_15864_KD_LSD1_SRP228812	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
PMC11024792-DataSheet_1.pdf-33-KLF2_KLF2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE172494_3_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE150669_2_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
intermediate gray layer of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37823
PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_1_TRC-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_foreskin fibroblast_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bed nuclei of the stria terminalis, anterior division, fusiform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10507
Nutritional deficiency, NEC_Skeletal Myocyte_GSE1776	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	0.923828
GTEX-R53T-1526-SM-48FEK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03184
Epididymis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MEOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3508
EDARADD	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-T5JC-0001-SM-3NMAK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.998372
Bed nuclei of the stria terminalis, posterior division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49738
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EGFR_drugactivation_19_GDS2146	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	0.772876
Lhx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.228
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05545
cation binding	GO Molecular Function Annotations 2015	1.0	null
Perturb_4199_KO_Fmr1_SRP075646	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.2517
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-LEF1_LEF1	Rummagene Transcription Factor Associations 2026	1.0	null
mRNA_SETDB1_19884255	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.915214
GTEX-X88G-0004-SM-47JZ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903929
Rectum adenocarcinoma_READ_TCGA-F5-6811-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11866_OE_Il13_ERP005901	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.3144
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE176008_4_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A13J-11A-13R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hyperactivity	IMPC Knockout Mouse Phenotypes	1.0	null
NCI-H1417	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1734	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Dorsal part of the lateral geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36055
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0008-SM-4DM6A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22208
PMC8065135-41467_2021_22068_MOESM6_ESM.xlsx-E_MYOG_binding_in_downreg-Unnamed_1_MYOG	Rummagene Transcription Factor Associations 2026	1.0	null
GSE186440,GSE186443_0_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CLPP_KO_GSE40207_378_mouse_Testies	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
r3 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2273
EN2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8843
memory t-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.31877
SW1271	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5307
GSE122215,GSE122217_0_v_4_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
shoot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065837
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2108
GSE216043_11_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE132369,GSE132371_3_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	1.0	null
BICR 31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39109
GSE142210_2_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Orbital area, medial part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07978
subgranular zone of caudal dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.928705
SOX2-21211035-LN229_GBM-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-8459-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE233679_14_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ACAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93276
GTEX-OIZI-0008-SM-2XCFD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8544
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
496100411_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.15995
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.932103
GTEX-SNMC-1326-SM-2XCFK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12411
persistence of hyaloid vascular system	IMPC Knockout Mouse Phenotypes	1.0	null
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE184892_7_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Embryo Loss	CTD Gene-Disease Associations	1.0	1.22112
PMC8224457-MSB-17-e9760-s005.xlsx-C_Ctrl_v_HMGB1-KD_IMR90-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P4QS-0008-SM-48TDY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16024
MAFK_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
morula	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.10106
SUPT1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.87659
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5552-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHL1	CCLE Cell Line Gene Expression Profiles	1.0	1.75304
GSE119564_1_v_0_zfp217_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14313
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.253
GSE102467_3_v_2_pazopanib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_11592_KD_CASP4_SRP345007	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.6021
GSE142210_3_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EP300_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_ID1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GSE176008_0_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.7546
TestisGermCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.834427
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.913658
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE223893_2_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLF5-25053715-YYC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
JAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17582
Perturb_8939_Mut_RB1_SRP220467	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-14.1267
GSE135030_8_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042721
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-1297	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
CTCF_fibroblast of villous mesenchyme_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_12_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
gastrointestinal tract	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
C32	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_2852_Mut_NRAS_SRP404927	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
PMC3921136-CIN-13-2014-021-s001.pdf-146-PAX3_PAX3	Rummagene Transcription Factor Associations 2026	1.0	null
blastomere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.09832
ATPSCKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52913
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XXEK-0008-SM-4BRW7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37546
PBX3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ventilator-associated lung injury_Lung Tissue_GSE2411	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.07736
H4K91ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-H1876	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12897
GSE233679_6_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2872
Perturb_4991_KO_Mettl5_SRP268611	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.70777
Parathyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Bed nuclei of the stria terminalis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04929
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0934
Acetazolamide_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0305557
NKM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE133087_1_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Thyroid primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.601
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20004
fallopiantube_8b	HPA Tissue Sample Gene Expression Profiles	1.0	1.06297
MZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.874071
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE148263_6_v_9_trim3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233679_5_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lateral vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78309
EOL-1-CELL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FXR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74367
GTEX-T2IS-0008-SM-4DM75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05759
GSE211931_0_v_3_ncoa4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal body weight	MPO Gene-Phenotype Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
r8 part of lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45239
bcl11b_18199763_brain_lof_mouse_gpl1261_gds3178	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.13708
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4115-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r6 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12395
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE91015_0_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE174498,GSE174500_2_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
mRNA_ZFX_17448993	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GTEX-VJYA-1326-SM-3GIJC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17951
GTEX-XBED-0008-SM-47JWO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76743
Immune system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.219
periderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.00109
GSE146612_1_v_3_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE133213_6_v_1_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNCA_KO_GDS4153_442_mouse_Cerebellum - 6 month	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12605
GTEX-VUSG-0008-SM-4KL24	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56887
hsa-miR-548q	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Blastopore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.631
T84	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XBEW-0008-SM-4AT3Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34319
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24598
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE195568_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Chromosome 15q24 deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.174
Neurula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.043
GSE231720,GSE231724_2_v_1_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19223
mantle zone of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05108
600MPE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.642447
PMC5749531-jci-128-96551-s002.xlsx-Mouse_SPOP_ERG_PTEN_WT-Hgene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
GSE159728,GSE159730_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE115363_3_v_5_esrrb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Developmental and epileptic encephalopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.145
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.25105
Prostate adenocarcinoma_PRAD_TCGA-EJ-7781-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE198794_2_v_3_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R53T-1626-SM-3GAEW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39044
GSE165939_2_v_1_poldip2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
GSE210580_3_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-6175-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10489
PMC9377669-tx1c00392_si_002.xlsx-Valproic_Acid-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210682_2_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE126463_4_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE226249_0_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE207302,GSE207303_0_v_2_tp53bp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-VUSH-0008-SM-47JWK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41502
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE164884_2_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NG25_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0289178
GSE205163,GSE205164_9_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE155852_0_v_2_apigenin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Liver Diseases	CTD Gene-Disease Associations	1.0	1.36504
Prostate	GTEx Tissue Gene Expression Profiles 2023	1.0	5.87846
hippocampus	HPA Tissue Protein Expression Profiles	-1.0	-1.87787
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.1894
EW-22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WHPG-0004-SM-3NMDO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11659
Osteoarthritis_Chondrocyte_GSE16464	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.29735
r6 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18438
cholecalciferol_mus musculus_gpl339_gse18993	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC10742386-pnas.2311372120.sd05.xlsx-DLX3_EVT-Gene_Symbol_DLX3	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Human - Motor Cortex - Cluster - VIP+ UG0898H09+ Layer 3-6 GABAergic neuron	HuBMAP Azimuth Cell Type Annotations	1.0	null
astrocytoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.671692
MBLAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46849
MAPK14_knockdown_101_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.79074
Wnt signaling pathway	PANTHER Pathways	1.0	null
Crus 1, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18249
spleen	HPA Tissue Protein Expression Profiles	-1.0	-0.721964
PMC12068594-pgen.1011693.s007.xlsx-MCR_vs_MCW-gene_id_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XV7Q-1526-SM-4BRWB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07264
GSE135030_11_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE120612_6_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11873652-mmc1.pdf-4-ETS1_ETS1	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_fibroblast of lung_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE162688_1_v_4_pink1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hoxa11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8593
Perturb_10396_KD_MAFB_SRP352813	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.30512
Paraventricular hypothalamic nucleus, parvicellular division, anterior parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.0466
496100529_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.26731
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.938457
GSE246184,GSE246195_0_v_1_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WFG7-0008-SM-4LMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56209
GSE154767_1_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-498	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GTEX-QXCU-0006-SM-2TC5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1453
LASV_FML29_24hr_24069471_GSE41300	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.00894
GSE239844_7_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE226249_2_v_4_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Adipose tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.373
GSE180185_9_v_5_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-7831-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
icSARS CoV_24Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.29126
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03472
GSE228181_2_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10489
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE226249_5_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
biological adhesion	GO Biological Process Annotations 2015	1.0	null
Perturb_5556_KD_KLF1_SRP317797	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.84997
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MH-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XQ3S-0001-SM-4B64K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0103
GSE210885_0_v_4_klf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE95077_5_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_9664_KD_TCF4_SRP188467	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.71822
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051656
OLIG2	ChEA Transcription Factor Targets	1.0	null
CTCF_fibroblast of foreskin _hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE112860_3_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20N-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.07874
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IJ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.545
GSE185944_0_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233679_5_v_13_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31342
GSE216043_10_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE225982_2_v_0_ezetimibe_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_6028_KD_KHDRBS1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.60025
SW1573	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35258
GTEX-WCDI-0002-SM-3P61U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29551
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6132-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE128844_0_v_1_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Immune System Diseases	CTD Gene-Disease Associations	1.0	1.02262
GSE213588_9_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pallidum, caudal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05169
GTEX-SNOS-0003-SM-3NMAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.913492
SW48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC5322933-pone.0172430.s013.xls-Immune_MSC_Single_Basal_vs_MSC-Unnamed_1_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
r4 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02956
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6826-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6281
GSE200352_1_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE235066_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100374_HIP_possible Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.75126
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01512
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K14ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE169571_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Belumosudil (mesylate)_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0160687
MRK-NU-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XUW1-0008-SM-4BOQH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34262
psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.192657
PMC6190866__F6	PFOCR Pathway Figure Associations 2024	1.0	null
GSE100863,GSE100864_2_v_1_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H2722	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0934
GSE140576_0_v_2_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE127790_13_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE173262_2_v_0_ash1l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04487
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5798892-41421_2017_3_MOESM7_ESM.xlsx-Veh_KO_vs_WT-Supplementary_Table_S2-1_Up-_and_downregulated_genes_in_ATF6_cells_relative_to_ATF6_cells_in_the_presence_of_Vehicle_early_passage_ATF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XBED-1626-SM-47JYN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918328
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC2694838-1471-2164-10-241-S2.xls-Sheet1-Regulated_genes_by_ZNF191_knockdown_ZNF24	Rummagene Transcription Factor Associations 2026	1.0	null
EZH2-18974828-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE173873_10_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-33a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
NCI-H1568	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Photoreceptor connecting cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.793
central gray substance of midbrain, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01016
HCC1162	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.960476
GSE157555,GSE157556_4_v_7_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE157555,GSE157556_4_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UMUC7	DepMap CRISPR Gene Dependency	1.0	3.34967
GSE108084_3_v_2_epinephrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4863-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HNRNPM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01086
GSE144750_1_v_0_six1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE205163,GSE205164_3_v_0_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.858779
medial amygdala, posterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.96858
Perturb_12299_KD_METTL3_ERP137121	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.49726
Perturb_15103_KD_KLF1_SRP319563	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.84997
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.943299
Spinal cord	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	5.0
CTCF_fibroblast of foreskin _hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_11647_KD_LOC399818_SRP113334	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.52809
GSE235066_7_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RCOR1	ChEA Transcription Factor Targets	1.0	null
HOXA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7645
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872554
GTEX-NPJ7-0008-SM-4E3JS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2098
PMC9377669-tx1c00392_si_002.xlsx-Entinostat-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10385841__F6	PFOCR Pathway Figure Associations 2024	1.0	null
r3 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1893
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18512
GSE157894_1_v_0_cystine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE151829,GSE151831_1_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SYPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09937
OCUBM	DepMap CRISPR Gene Dependency	1.0	4.5089
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC8283158-mmc2.xlsx-TCF4_Glut-Gene_TCF4	Rummagene Transcription Factor Associations 2026	1.0	null
REST_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XBED-0003-SM-47JWP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23038
lateral hypothalamic area, anterior region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.839254
GSE189653,GSE203344_4_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-515-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
SK-MEL-31	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.22793
molecular layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.855414
SRY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12824
GTEX-OXRK-0326-SM-3NB3R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889533
zygote	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.093573
GSE189356_5_v_6_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE127790_5_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LRP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2734
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.3047
amygdaloid complex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10704
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.280717
GSE109565_12_v_4_glyphosate_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Extrinsic component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.328
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cuneiform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.28169
Lung squamous cell carcinoma_LUSC_TCGA-56-7582-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Seminal vesicle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
r6 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04103
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-6647-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IV	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.891102
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
nes	HPA Cell Line Gene Expression Profiles	1.0	1.50001
GSE146247_0_v_1_sirt7_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903801
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.959805
MDAMB175VII	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.801154
SRC	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFG8-0008-SM-4LVN6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73746
Perturb_18451_KD_H2AFJ_ERP124778	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.8018
PARP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02356
CTCF_WI38_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SJXC-0008-SM-4DM7G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4321
GSE167373_0_v_3_rbfox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4260	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GTEX-XMD3-0008-SM-4AT4V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99274
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q1-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12621392-12864_2025_12212_MOESM2_ESM.xlsx-GSF-S_72h_1-Unnamed_0_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
BSX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5093
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE130081,GSE130082_5_v_10_neil2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
t60-adrenal_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	9.44566
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.079
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.955639
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YQ-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9224
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5149
HOP-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.887034
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08075
H3K4me3_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_8043_KO_Zeb2_SRP261907	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.59991
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.831516
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.97925
GSE48812_0_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE150055_0_v_2_melphalan_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE193258,GSE193259_9_v_15_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
valproic acid_homo sapiens_gpl6883_gse26940	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_6027_KD_KHDRBS1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.93721
GSE162892_4_v_2_sox9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
OV7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34638
GSE173873_0_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE106661,GSE106665_0_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.81592
Bed nucleus of the anterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00981
GTEX-O5YT-0008-SM-4E3IQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838997
Medial amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57958
Lung adenocarcinoma_LUAD_TCGA-50-6591-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pulmonary hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.370368
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.45053
496100657_FWM_probable Alzheimer's disease_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.80408
GSE157555,GSE157556_3_v_7_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebral degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.340906
r4 part of lateral vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69505
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-JUN_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210870_0_v_2_snai1_human	RummaGEO Gene Perturbation Signatures	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.4829
SUZ12-16625203-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE242096,GSE242098_1_v_0_med1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.38943
Infralimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19057
Liver hepatocellular carcinoma_LIHC_TCGA-MR-A8JO-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUZC-0008-SM-4BOQG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33502
HAND2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
malignant glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.413901
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70J-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EED-16625203-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.83028
Bladder Urothelial Carcinoma_BLCA_TCGA-SY-A9G0-01A-12R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148657_2_v_1_cd44_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Retinol-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
HMBS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10603
BHLHE23	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8123
congenital heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.46466
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216273,GSE216292_14_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-548ag	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.29673
GSE211262,GSE211263_3_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4489	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
mRNA_POU5F1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.68603
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
r5 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05277
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059664
GSE235945_1_v_0_pikfyve_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
orbital frontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.96516
YY1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
293-F FreeStyle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.89
GSE171292_5_v_2_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.835746
Perturb_9601_KO_Satb2_SRP307576	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.6519
hsa-miR-3116	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
SNU182	DepMap CRISPR Gene Dependency	1.0	4.66425
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE130081,GSE130082_5_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S7PM-0008-SM-3NM9Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03653
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8002-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Neurotoxicity Syndromes	CTD Gene-Disease Associations	1.0	1.32816
hsa-miR-3688-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
GSE113734_1_v_2_qprt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6097700-pgen.1007515.s008.xlsx-S2_Table-S2_Table_SATB2_Cort_gene-set_list_SATB2	Rummagene Transcription Factor Associations 2026	1.0	null
Paraventricular hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58445
Mammary Neoplasms, Animal	CTD Gene-Disease Associations	1.0	1.07696
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_2_TBRC-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
USF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE133764_1_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-450b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6221-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
Perturb_5436_KO_Rspo3_SRP363653	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.0954
GSE196104,GSE196106_3_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.13574
Ameloblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.734
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.922752
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08468
GSE164874_5_v_8_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
FAM204A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40612
Indacaterol (maleate)_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0251388
GTEX-TKQ2-0008-SM-4DM5L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65514
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5486
PMC12621392-12864_2025_12212_MOESM2_ESM.xlsx-GSF-F_72h_1-Unnamed_0_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
FGFR1_knockdown_94_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.7666
GSE119978,GSE180930_2_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ERBB4	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1364
GSE167956_1_v_0_trim28_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Paraflocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07136
GSE150669_0_v_3_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-4496	TargetScan Predicted Conserved microRNA Targets	1.0	0.159923
GTEX-WFON-2226-SM-3TW8W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922876
Rectum adenocarcinoma_READ_TCGA-F5-6810-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2938-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11655_KD_MCFP_SRP113334	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.33465
superior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.913893
SRC_overexpression_276_GSE37428	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.39595
lymphoid tissue	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
KYSE450	CCLE Cell Line Gene CNV Profiles	1.0	1.46102
JEKO-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.958708
fat_a.V1	HPA Tissue Sample Gene Expression Profiles	1.0	1.31745
Usher syndrome type 1F	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
Lung adenocarcinoma_LUAD_TCGA-55-8299-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5483-01A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H9	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.871783
HT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_HEK293_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.95611
GSE233679_6_v_13_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE198254_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE133691_1_v_3_lgr5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135030_11_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF701	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.5336
GSE174522_1_v_0_spp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6024-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Delta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.143
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10489
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.838168
GTEX-QDT8-0008-SM-48U2F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982109
GSE233679_5_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE150669_0_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.7002
GSE226249_5_v_3_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE225869_1_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GATA2	ENCODE Transcription Factor Targets	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.452
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.2702
GTEX-OOBK-0008-SM-3NB27	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10684
NCI-H23	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6938-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Poisoning	CTD Gene-Disease Associations	1.0	1.45883
Prostate adenocarcinoma_PRAD_TCGA-EJ-7785-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE176008_8_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RNF2-16625203-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
SA1-22415368-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE230744,GSE237803_5_v_3_hira_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hindlimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.141244
Extrinsic component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.528
u937	HPA Cell Line Gene Expression Profiles	-1.0	-0.894171
inner nuclear layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.578816
GTEX-S3XE-0008-SM-3NM8O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91988
GSE198794_2_v_1_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Methicilin-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12661646-dmm-18-052290-TableS7.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
Hydroxyfasudil_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0220961
AF4-26711339-SEM-HUMAN-BLOOD-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
GSE240468_3_v_6_nfyc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Anterodorsal preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10911
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.974536
hsa-miR-4519	TargetScan Predicted Conserved microRNA Targets	1.0	0.389112
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.376
GSE224096_3_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Larotrectinib sulfate_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.032731
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23574
Perturb_9710_KD_SMARCB1_SRP279089	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-13.9569
GSE216043_10_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.114326
GSE233679_6_v_11_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
E2F1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of r1Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11402
Perturb_5732_KO_Gpr124_SRP064844	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.32901
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_16435_KD_APP_SRP187586	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4918-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.84213
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PHB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83187
Perturb_14245_KO_IKZF3_SRP139731	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.41564
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36534
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Dextrometh-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
BRD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37994
GTEX-U3ZN-2626-SM-3DB7T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850044
Lateral vestibular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.561
GTEX-QESD-0008-SM-447B2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57401
H3K4me3_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE210101,GSE210114_6_v_9_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
short tibia	IMPC Knockout Mouse Phenotypes	1.0	null
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.245
Notochord	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.052
lateral (dentate) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29413
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU1J-0008-SM-46MV9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47321
Elimusertib hydrochloride_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0341161
CTCF_fibroblast of lung_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4789-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.4174
P53-22387025-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-W3-A825-06A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Edema	CTD Gene-Disease Associations	1.0	1.46909
INHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18178
GSE229344_1_v_0_cyb5r3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Ascorbic_Acid-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
GSE221356_1_v_0_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210655_3_v_7_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7857731-elife-63093-supp5.xlsx-ECMdegs-pB-MITF-FLAGvs_pB-FLAG-Unnamed_3_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE213228_4_v_3_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46532
GSE228181_2_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE242199_2_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.7409
primary auditory cortex (core)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.840249
GSE151090_2_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Superior colliculus, motor related, intermediate gray layer, sublayer c	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56146
Lung adenocarcinoma_LUAD_TCGA-38-4627-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE118939_1_v_0_nras_human	RummaGEO Gene Perturbation Signatures	1.0	null
chr4_137368492_C_T_b38	GTEx eQTL 2025	1.0	1.16155
periventricular stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22526
MZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02653
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12882
COLO678	CCLE Cell Line Gene CNV Profiles	-1.0	-1.84011
PMC8208823-mmc2.xlsx-CDX2-dataset-feature_CDX2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CEBPD-23245923-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SG in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.849046
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6241
Kidney Chromophobe_KICH_TCGA-KO-8407-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.896245
DND-41	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Hematopoietic cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	4.217
GSE148695,GSE167284_2_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30325
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10489
GSE161055,GSE161056_1_v_0_hira_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-02A-21R-A36H-07,TCGA-DU-6404-02B-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE95077_1_v_3_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RMGI	CCLE Cell Line Gene CNV Profiles	1.0	1.57928
EED	ChEA Transcription Factor Targets	1.0	null
GSE174498,GSE174500_3_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
r2 part of vestibular sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81333
neural plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.173396
GSE173262_6_v_0_ash1l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intracranial hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.574217
sirolimus_homo sapiens_gpl2895_gse16944	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.558856
GSE144796_3_v_0_linagliptin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
451LU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2857-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer CP in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06968
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15909
Perturb_6446_OE|KD_EGFR|TRIM24_SRP100743	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
hippocampus (hippocampal formation)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.68177
oral mucosa	HPA Tissue Protein Expression Profiles	-1.0	-0.721964
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE118766_2_v_0_ifng_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_15_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE235066_7_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.955726
GSE173578_1_v_0_atf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PGBD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02396
GSE123943_1_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rimonabant_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0428281
doxorubicin_homo sapiens_gpl10558_gse42531	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC9287735-mmc8.xlsx-MI_Related_Genes-TNF_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6364-01A-21R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW626	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ETS1-22383799-G1ME-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE226983_1_v_0_ddx5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
USF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r1Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14849
Pulmonary vascular system_CT1_fibroblast of pulmonary artery	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6148-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86462
bed  nucleus of stria terminalis, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.873823
Animal cap	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.451
hela	HPA Cell Line Gene Expression Profiles	-1.0	-0.894171
GSE213588_8_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
breast	HPA Tissue Protein Expression Profiles	-1.0	-0.721964
Kidney renal papillary cell carcinoma_KIRP_TCGA-EV-5903-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CLPP_KO_GSE40207_379_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE218580_1_v_4_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
t70-white-adipose_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.45282
GSE213588_8_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE93309_1_v_0_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Glucose Intolerance	CTD Gene-Disease Associations	1.0	1.09751
orbital frontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.845761
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17427
colorectum	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-PBX3_PBX3	Rummagene Transcription Factor Associations 2026	1.0	null
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36534
Isocorydine_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0233613
PLSCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27967
Spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26915
GSE201882,GSE201883_3_v_4_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6242972-41467_2018_6699_MOESM5_ESM.xlsx-Sheet1-Supplementary_Data_2_Significantly_up-_and_down-regulated_genes_adj_P_Val_0_05_upon_TBX2_knockdown_in_the_IMR-5_75_cell_line_TBX2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HMV-II	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4662a-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.32519
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.9231
paraventricular nucleus, cap part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31929
Pyridoxine (hydrochloride)_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0243629
GTEX-RVPU-0008-SM-3NM8B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08342
syndactyly	MGI Mouse Phenotype Associations 2023	1.0	null
PMC5322933-pone.0172430.s013.xls-HG_MSC_Single_Basal_vs_MSC_AD_B-Unnamed_1_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XMK1-1126-SM-4IHJ8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8618
GSE221577_1_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain_CT2_CGE 284	HuBMAP ASCT+B Annotations	1.0	null
GSE213588_9_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
small_intestine	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.16315
GTEX-WL46-2826-SM-3LK81	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857172
Hatching gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.365
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.2833
POU5F1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2142
Acute Myeloid Leukemia_LAML_TCGA-AB-2899-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
increased lean body mass	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-S33H-0008-SM-4AD6C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98361
GSE162892_4_v_2_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03257
GSE216043_3_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE123943_4_v_5_sox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7012-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.152
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040628
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPK5-0008-SM-4IHJD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60616
GSE133505_5_v_4_myf6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Adipocyte	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
Bed nuclei of the stria terminalis, anterior division, magnocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33235
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.279307
GSE174701_1_v_7_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
HS688AT	CCLE Cell Line Gene Expression Profiles	1.0	2.17798
GSE202434,GSE202438_6_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WRHU-0006-SM-3MJF6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34176
dexamethasone_rattus norvegicus_gpl1355_gse29912	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BMI1-23680149-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-S4P3-1326-SM-4AD6V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852645
GSE240645_3_v_2_u90926_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE176555,GSE176556_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE183994_1_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
STAT3-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
r3 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14211
CTCF_cardiac fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3N_Peaks_YAP1FAM118B_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JD-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLVL	DepMap CRISPR Gene Dependency	1.0	2.09389
GSE201270,GSE201272_5_v_1_mybl2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE167004_0_v_3_thpo_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Stomach	GTEx Tissue Gene Expression Profiles 2023	1.0	0.999243
mRNA_SALL4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Pericyte_Lung_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H5-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-769-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
parvicellular interstitial nucleus of the posterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59667
FYN	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SG in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07641
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Change_in_both_CSDE1_KD_hESCs-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.66734
JUN_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE264621_1_v_6_secretin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC3573965-1471-2407-12-422-S1.pdf-53-POU3F3_POU3F3	Rummagene Transcription Factor Associations 2026	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
Perturb_17047_KD_IRF4_SRP201887	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-15.9695
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53909
GTEX-U4B1-0008-SM-4DXUW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34663
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Ansiform lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08947
Perturb_13894_KD_BRCA1_SRP135799	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.61328
GSE198794_0_v_1_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.159
Tcf21	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.7278
SUM1315MO2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.19116
GSE135030_8_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
liminal part of the r6 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38336
GTEX-R45C-0008-SM-48FF2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01692
GTEX-S341-2026-SM-2XCAA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943064
GTEX-P4QR-0008-SM-48TE2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851223
GTEX-XYKS-0002-SM-4BRWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52301
Lung adenocarcinoma_LUAD_TCGA-44-2661-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX2_01_350	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-1.01746
TMOD3_KO_GDS4827_418_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC12358249-supplementary_table_s5_ioaf064.xlsx-DMRT1_-_vs_WT__4_months-Unnamed_1_DMRT1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE48812_4_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
SUPHD1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.66105
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WCDI-0008-SM-47JYE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900175
GSE135352_2_v_3_napabucasin_human	RummaGEO Drug Perturbation Signatures	1.0	null
lateral posterior nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44874
GTEX-WFON-1826-SM-3GILG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00155
GSE71529,GSE71558_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE200352_4_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-1267	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GSE195568_3_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
gallbladder_5c	HPA Tissue Sample Gene Expression Profiles	1.0	0.923736
hsa-miR-33b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5358-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TIMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3006
20490655-ST3	GeneSigDB Published Gene Signatures	1.0	null
EXOC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16867
GSE216043_10_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01631
SW 837	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.911151
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.3719
shortened ST segment	MGI Mouse Phenotype Associations 2023	1.0	null
GSE151090_5_v_1_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6231
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29009
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10489
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15969
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.930684
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-7637-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Levothyrox-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
JAK1_knockdown_160_GSE37012	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.8297
P2URK562	DepMap CRISPR Gene Dependency	1.0	6.36234
GSE216147_0_v_1_rbm20_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE214596,GSE214598_1_v_3_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CHST15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31309
GSE120370_4_v_1_thrombin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10247733-41408_2023_863_MOESM4_ESM.pdf-574-ZSCAN1_ZSCAN1	Rummagene Transcription Factor Associations 2026	1.0	null
SYMPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.71495
GSE111035,GSE111040_8_v_9_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13574
GSE206516,GSE206518_5_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE168798_0_v_1_isg15_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U8T8-0008-SM-4DXSP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.537
Dabrafenib_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0509067
SUMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28761
inner CP in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01521
PMC3172216-pone.0023082.s005.xlsx-EGR1_expression_table_txt-CLID_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.936879
SYCE1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38454
PF-382	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08991
r3 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02795
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32413
GSE128099,GSE128159_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SW982	DepMap CRISPR Gene Dependency	1.0	7.54359
GSE202434,GSE202438_15_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UBF1/2-26484160-CHIP-SEQ-FIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-R55C-0008-SM-48FCF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958413
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67119
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37995
Lung squamous cell carcinoma_LUSC_TCGA-37-4141-01A-02R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.839652
IZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.897517
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE235701,GSE261434_2_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE119978,GSE180930_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
dorsolateral SC part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53925
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051513
H3K9me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XK95-0426-SM-4AT4R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882403
GTEX-T5JW-0008-SM-4DM5X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59818
BACH1_01_59	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.93818
Perturb_11654_KD_MCFP_SRP113334	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.00075
MET_knockout_250_GDS3148	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.05713
Folic acid_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0262384
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Decreased_in_both_CSDE1_KD_hESC-gene_short_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
OLIG2-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE127790_4_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TOV112D	CCLE Cell Line Gene Expression Profiles	1.0	1.97999
KLF7_01_340	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.12854
FAM216A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20338
GSE202284,GSE202289_12_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.42113
GSE233679_14_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216043_7_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12685885-Table1.xlsx-Table_S9-Du_PanCancer_SOX6_TrsFib_SOX6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Ampicilin-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
Patent foramen ovale	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.316
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.39567
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
astroglia	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.175765
ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.177229
increased lean body mass	IMPC Knockout Mouse Phenotypes	1.0	null
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2532
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0065
GSE144346_0_v_1_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hyperpallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.613
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53139
GSE199606_5_v_7_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
glioblastoma multiforme	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.587833
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
14633610-Table2	GeneSigDB Published Gene Signatures	1.0	null
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8335
GSE206516,GSE206518_0_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
periventricular stratum of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5567
SOX2_Deficiency_GDS4853_321_human_AZ-521 gastric cancer (GC) cell line - 18 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05385
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.45616
r1 part of superior vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11491
GSE200352_4_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.48602
GSE202434,GSE202438_10_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-U3ZH-1426-SM-4DXSR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920169
Human - Fetal Development - L2 - Pancreas-Smooth muscle cells	HuBMAP Azimuth Cell Type Annotations	1.0	null
GSE222758_0_v_3_clofazimine_human	RummaGEO Drug Perturbation Signatures	1.0	null
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.427636
Perturb_12157_KD_LIN28/LIN28A1_SRP061243	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.84574
Lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10255
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4457140-Data_Sheet1.PDF-31-PRDM1_PRDM1	Rummagene Transcription Factor Associations 2026	1.0	null
SG in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32248
GSE169356_0_v_5_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE65617_0_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Rhomboid nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.743
EPCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0196
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.960476
GTEX-RTLS-0008-SM-48FET	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75235
Cadherin, N-terminal	InterPro Predicted Protein Domain Annotations	1.0	null
RNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68672
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XOT4-0226-SM-4B66Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917537
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.639
GSE93309_1_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2142
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0934
Prostate adenocarcinoma_PRAD_TCGA-G9-6365-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-7631-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRL-0008-SM-3NB29	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07978
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE171401_1_v_2_adnp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Fluvoxamine (maleate)_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0349418
GSE196962_2_v_1_parg_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE126345_7_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.06698
VI, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.57364
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052183
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.85332
KYO1	DepMap CRISPR Gene Dependency	1.0	5.95779
IRF1-21803131-MONOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE158431_5_v_1_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
COLO 678	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.79602
GSE151829,GSE151831_7_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.95111
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-RN64-1626-SM-48FD7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990263
GSE183335,GSE183351_1_v_0_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
19038878-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
germ layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.227445
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.1917
mRNA_DLX3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3WC-11A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.069764
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.87074
GSE237666,GSE237688_1_v_2_igf2bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_14933_KO_miR302_SRP221297	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE135030_11_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE146982_7_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SW579	DepMap CRISPR Gene Dependency	1.0	2.83148
IGR-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
toe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.81565
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.37073
astroglial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.176723
Gut	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	5.0
developmental process	GO Biological Process Annotations 2015	1.0	null
ACSBG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23202
Tooth enamel	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.778
GSE154577_6_v_12_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10353540-Table_1.xlsx-HCC1954_AR_vs_HCC1954_A-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE245407,GSE245412_0_v_1_smurf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
organ development	GO Biological Process Annotations 2015	1.0	null
CEBPD	ChEA Transcription Factor Targets	1.0	null
hsa-miR-1323	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE145915_5_v_1_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.06445
ac88	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.63
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HAND1_cust_neg_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16426
GSE198165,GSE198166_8_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H2023	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Alimentary canal	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE85565_1_v_0_tcf21_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3BM-11A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R53T-0008-SM-48FEW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2653
hsa-miR-488	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
syndactyly	IMPC Knockout Mouse Phenotypes	1.0	null
Perturb_13891_KD_BRCA1_SRP135799	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
superior colliculus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0815
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE221327_5_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10794847-mmc3.xlsx-PBRM1_KD_down-Table_S2_Differentially_expressed_genes_with_PBRM1_knockdown_in_the_differentiation_state_Related_to_Figure_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
786-0	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EU-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE105406_0_v_3_ptcd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SNOS-1426-SM-32PLY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85171
STAT3-1855785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
REST_PFSK-1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_NIPBL_20720539	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
ChIP_SUZ12_16625203	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE158182_4_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.264
TCF12	ENCODE Transcription Factor Targets	1.0	null
smooth muscle	HPA Tissue Protein Expression Profiles	-1.0	-0.721964
GSE202434,GSE202438_15_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PKBalpha_KO_GDS1784_197_mouse_Embryonic fibroblasts (MEFs) - 48h	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8625-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.277
GSE157383_3_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11461876-42003_2024_6975_MOESM3_ESM.xlsx-Supplementary_Data_1-Supplementary_Data_1_Differentially_Expressed_Genes_HSE_THP1_Vs_THP1_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE180185_7_v_8_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02009
GSE81803,GSE81912_3_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-W5X1-2326-SM-3GIL6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09433
CAMA1	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.624679
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A3JJ-11A-12R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4769-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GSE92364_0_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SK-MEL-24	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
SMSCTR	DepMap CRISPR Gene Dependency	1.0	2.40275
dorsolateral part of Lat	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50361
Learning Disorders	CTD Gene-Disease Associations	1.0	1.68084
GSE128076_1_v_3_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11558691-tables5_bbae592.xlsx-SOX17-Genes_SOX17	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH28	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52116
endometrium_8b	HPA Tissue Sample Gene Expression Profiles	1.0	1.18821
GSE213988_0_v_1_rrm2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE129241_3_v_6_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.4474
GSE112365_0_v_1_sirt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC2866657-pone.0010547.s001.xls-ERG-high-GENES_DOWNREGULATED_IN_ERGhigh_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
wing	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.676172
GTEX-U3ZN-0002-SM-3NMDF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.942315
GTEX-XOTO-0008-SM-4GICE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50229
Perturb_9651_KO_TREX1_SRP355094	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.53297
SNU-407	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-6595-01A-12R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57161
PMC7338542-41389_2020_247_MOESM5_ESM.xlsx-BRN2_2_of_3_UP_48_h-Symbol_POU3F2	Rummagene Transcription Factor Associations 2026	1.0	null
G402	DepMap CRISPR Gene Dependency	1.0	2.97112
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
DDX24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11512
GSE125862_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LBHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05481
liver	GTEx Tissue Gene Expression Profiles	-1.0	-0.895912
limb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.154309
Brain Diseases	CTD Gene-Disease Associations	1.0	1.32015
SUZ12-18974828-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-X4XY-0008-SM-46MVL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43621
GSE213588_9_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3M_Peaks_YAP1MAMLD1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
viscus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE48812_4_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Spleen	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE125782_3_v_2_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-4698	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
r1 part of vestibular nucleus Y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21847
Perturb_6035_KD_MBD3_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.8376
GSE148692,GSE148695_2_v_6_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
pallidohypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.2087
parasolitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.1712
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59442
Ovary	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Myosin X complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.952
HH	CCLE Cell Line Gene CNV Profiles	-1.0	-2.08154
PMC8212786-DataSheet_4.xlsx-CESC-ZBED3_ZBED3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE116580_0_v_1_smug1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE130081,GSE130082_0_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10489
Declive (VI), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18538
Catenin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.434
lateral part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76295
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
496100566_FWM_no dementia_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.26856
mRNA_MYBL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
corneal opacity	IMPC Knockout Mouse Phenotypes	1.0	null
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.6415
MMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35912
superficial stratum of AHy	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86612
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4Q7-0008-SM-3NM8A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50068
decreased total body fat amount	MGI Mouse Phenotype Associations 2023	1.0	null
Disseminated Intravascular Coagulation	CTD Gene-Disease Associations	1.0	1.09011
primary visual cortex (striate cortex, area V1/17)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06829
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cell-cell adhesion via plasma-membrane adhesion molecules	GO Biological Process Annotations 2015	1.0	null
Perturb_8471_Mut_IDH1_SRP099826	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.84741
GSE148692,GSE148695_2_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NRL_Deficiency_GDS1693_235_mouse_Photoreceptors cells of retinas at E16	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
vitamin c_homo sapiens_gpl570_gse11919	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Somite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.249
HS863T	CCLE Cell Line Gene Expression Profiles	1.0	1.68289
ETK-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_4869_KO_GATA2_SRP059386	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.58697
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16244
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.983408
superficial stratum of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08604
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9306206-12915_2022_1367_MOESM6_ESM.xlsx-Table_S7_-_JIP-Gene_SMAD4	Rummagene Transcription Factor Associations 2026	1.0	null
Uterine endometrium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SUZ12-16625203-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19804
GSE165548_2_v_13_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Leflunomide-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH23	CCLE Cell Line Gene CNV Profiles	-1.0	-2.0646
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
astroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.176723
GSE162892_4_v_5_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-U3ZN-2526-SM-3DB7V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963415
GSE145915_3_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
inferior occipital gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.27998
dorsolateral TG part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14902
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_13895_KD_BRCA1_SRP135799	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-Q2AH-0008-SM-48U2J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997019
COLO800	DepMap CRISPR Gene Dependency	1.0	2.93996
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.964733
KYSE-270	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11941
Perturb_5438_KO_Kansl3_SRP225948	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.19251
DDX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12288
IRF1-21803131-MONOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6599263-13073_2019_654_MOESM2_ESM.xlsx-CAR1_tsv-gene_name_NR1I3	Rummagene Transcription Factor Associations 2026	1.0	null
ANAPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4069
dorsal lateral geniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40651
hsa-miR-4804-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Binimetinib_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0464085
CCDC43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14287
GSE138841_0_v_1_trim6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-SUCS-0008-SM-4DM53	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901839
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.954484
BRD4_druginhibition_224_GSE50865	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.20608
NFIC	ENCODE Transcription Factor Targets	1.0	null
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.83028
hsa-miR-23a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Thorax	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4843-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF12_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXA5	JASPAR Predicted Transcription Factor Targets	1.0	null
PMC8481886-Table_2.xlsx-A_subsets-common_MSC_HSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE103309_2_v_0_ube3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Congenital Abnormalities	CTD Gene-Disease Associations	1.0	1.29502
Lung adenocarcinoma_LUAD_TCGA-86-8358-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74915
Prostate adenocarcinoma_PRAD_TCGA-EJ-7314-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.865695
Medial amygdalar nucleus, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15548
medial (fastigial) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36615
Perturb_6368_KD_ETV1_SRP264999	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.7963
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	12.9196
PPP1R3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21536
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09118
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.727494
Perturb_11664_KD_PROK2_SRP113334	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.28135
GSE210101,GSE210114_5_v_9_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LN443	CCLE Cell Line Gene CNV Profiles	-1.0	-2.74591
H3K4me3_Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE203308_1_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7061-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
astrocytoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.622639
CTLL-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.91
GSE130437_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE142210_2_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Adipose - Subcutaneous	GTEx Tissue Gene Expression Profiles 2023	1.0	1.72884
PMC13138062-mmc7.xlsx-DUGs_ESR1_targets-DUGs_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE205163,GSE205164_5_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Sarcoma_SARC_TCGA-QQ-A8VH-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral tuberal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.65158
YAP1-20516196-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_6977_OE_ALOX12_SRP321065	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PELP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08468
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64112
PMC12661646-dmm-18-052290-TableS9.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
Paraflocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16805
KMS-21BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50159
CADO-ES1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE221327_5_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pontocerebellar hypoplasia type 15	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.692
GSE214382,GSE214383_6_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
GTEX-OIZG-0005-SM-2HMJC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.919176
GSE149880_2_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MMAC-SF	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE242199_9_v_11_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RBM8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82079
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5891-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE198165,GSE198166_7_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SK-GT-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC12621392-12864_2025_12212_MOESM2_ESM.xlsx-GSF-F_72h_2-up-regulated_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
PMC9377669-tx1c00392_si_002.xlsx-Teriflunomide-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5798892-41421_2017_3_MOESM8_ESM.xlsx-down-regulated-Supplementary_Table_S3_Up-_and_downregulated_genes_in_ATF6-_-_hMSCs_compared_to_ATF6_hMSCs_late_passage_ATF6	Rummagene Transcription Factor Associations 2026	1.0	null
CSNK2B	Pathway Commons Protein-Protein Interactions	1.0	null
GSE213588_9_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.858636
Perturb_6279_KO_TP53_SRP200689	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.95465
neurological	GAD High Level Gene-Disease Associations	1.0	0.293278
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49155
mantle zone of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29823
rostral putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20051
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NC-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE48812_0_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
heart muscle	HPA Tissue Protein Expression Profiles	-1.0	-0.721964
PA-TU-8902	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.06445
ChIP_MTF2_20144788	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
I-II	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.28116
VIIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.74489
BL5018 (RBM34)	NURSA Protein Complexes	1.0	null
JHU029	DepMap CRISPR Gene Dependency	1.0	3.20888
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC12661646-dmm-18-052290-TableS5.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-935	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GSE89018_10_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10489
upper (rostral) rhombic lip_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.55756
GTEX-OHPN-0008-SM-4E3HW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23405
GSE135030_11_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE119564_1_v_3_zfp217_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.051984
SG in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11811
pcgf2_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.240767
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03826
PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Unnamed_1_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
Superior colliculus, motor related, deep gray layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48421
superficial stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1864
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20Q-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE233679_6_v_2_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Celecoxib_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0163993
GSE182179_5_v_4_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.65755
NCI-H2110	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RHOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34397
GSE138863_3_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Paroxetine-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R7-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BFTC905	CCLE Cell Line Gene CNV Profiles	-1.0	-2.7449
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.984469
pancreas_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.08274
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10489
Temporal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20737
GTEX-TSE9-0008-SM-4DXT8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52946
GTEx Nerve 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-10.1142
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE214596,GSE214598_1_v_2_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE128844_0_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Ltk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.908
YAP1	ChEA Transcription Factor Targets	1.0	null
GSE167546_1_v_2_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7103-01A-21R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Buspirone-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-548ai	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4708
Fetal Death	CTD Gene-Disease Associations	1.0	1.48967
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE97278,GSE97280_2_v_3_nsd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5890-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09709
GTEX-UTHO-0008-SM-4JBID	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27509
Perturb_642_KD_FASTKD1_SRP299834	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.06667
ganglion cell layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.304279
heart septal defect	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.705144
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10489
Hindbrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
WM35	COSMIC Cell Line Gene Mutation Profiles	1.0	null
pretectal region	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15741
Vagina	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
mantle zone of r5Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30365
H3K9ac_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Thyroid Diseases	CTD Gene-Disease Associations	1.0	1.1977
pou5f1_20526341_human_embryonic_stem_cells_hesc_lof_human_gpl6947_gse21135	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.858505
Perturb_14591_KD_SUV420H2_SRP119315	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
dorsal septopreoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11624
GTEX-R55G-0008-SM-48FEX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16495
hippocampus (hippocampal formation)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.56814
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ATR_knockdown_120_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.65721
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00851
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.420385
central gray of the pons, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.837173
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18578
GSE96777,GSE96778_3_v_2_zbtb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SNCA_KO_GDS4153_528_mouse_cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Gastrointestinal tract	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4789-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
perifornical nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.22159
Tomivosertib_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00939478
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31808
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
adult testis	HPM Cell Type and Tissue Protein Expression Profiles	-1.0	-1.16984
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.236
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12093
placenta_6b	HPA Tissue Sample Gene Expression Profiles	1.0	0.9238
HLFA	CCLE Cell Line Gene Expression Profiles	1.0	1.84898
GATA3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04344
GSE142210_4_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.48944
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.829588
PMC7857731-elife-63093-supp5.xlsx-ECMdegsTCGAMITFlowvs_high-Differentially_expressed_ECM_genes_in_MITFlow_vs_MITF_high_tumours-SKCM_TCGA_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE120415,GSE120447_0_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE235066_4_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Human - Motor Cortex - Cluster - VIP+ LINC01013+ Layer 1-5 GABAergic neuron	HuBMAP Azimuth Cell Type Annotations	1.0	null
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_16736_KO_Tug1_SRP176442	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.31647
GTEX-XBEW-0002-SM-4AT5O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03762
JHH7	CCLE Cell Line Gene CNV Profiles	1.0	1.53392
hsa-miR-4526	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
abnormal postnatal growth/weight/body size	MPO Gene-Phenotype Associations	1.0	null
LN-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
medial amygdala, anterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4216
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.18261
GTEX-Q734-0008-SM-48U2I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24065
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03826
Perturb_4992_KO_Mettl5_SRP268611	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.90306
496100546_TCx_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.17799
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8423434-mmc7.xlsx-OCT4_Primed-Genes_n_912_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
Urate levels (BMI interaction)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.604576
BHLHA15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6698
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
inner CP in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02593
A-Vietnam-1203_CIP048_RG4-2004(H5N1)HAAvirmut_2day-MOI-10^4_None_GSE37572	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.71223
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10489
SUZ12-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Posterodorsal preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75091
FOXP2	ENCODE Transcription Factor Targets	1.0	null
inner SZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01635
RT11284	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37167
Perturb_9018_KO_YAP1_SRP132362	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Bendamustine_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0187884
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.92823
GTEX-U3ZG-0001-SM-47JYF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08706
GSE158320,GSE183351_0_v_1_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC13138062-mmc7.xlsx-DUGs_E2F1_targets-DUGs_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
VMRC-LCD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
lateral portion of the shell	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.999467
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66028
GSE213588_9_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25289
ERBB2_knockdown_236_GSE8373	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.53997
GTEX-QDT8-0226-SM-32PL4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982065
GTEX-XUYS-0226-SM-47JX1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988002
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.83028
GSE233679_6_v_4_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5204
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21117
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K36me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05925
PMC5789885-41467_2017_2812_MOESM4_ESM.xls-Supplementary_Data_1-Supplementary_Data_1_Non-cardiac_mesoderm_and_endoderm-permissive_differentiation_of_EOMES_KO_hESCs_EOMES	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10181932-41588_2023_1366_MOESM4_ESM.xlsx-Supplementary_Table_2-Supplementary_Table_2_Additional_information_for_all_SOX9-dependent_genes_SOX9	Rummagene Transcription Factor Associations 2026	1.0	null
GSE135514_8_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-N7MS-0011-R11A-SM-2HMJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.919768
Perturb_11946_KO_IRF2_SRP096865	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.02281
OVTOKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04934
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE202434,GSE202438_3_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mRNA_SALL4_19060217	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
PMC10319804-41467_2023_38747_MOESM9_ESM.xlsx-KHSRP_KD_genes_down-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TMZS-0008-SM-47JWM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70679
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Bed nuclei of the stria terminalis, posterior division, transverse nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4798
NCIH2106	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48079
medial parabrachial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.27546
GSE63048_11_v_6_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SOX9-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
III, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.32777
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.915591
GSE199606_5_v_7_csf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.960476
GSE111035,GSE111040_3_v_12_plag1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14526
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Gene_Name_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
ion binding	GO Molecular Function Annotations 2015	1.0	null
Obesity-related traits	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.609691
RAD21_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rosiglitazone_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0161134
GTEX-SIU8-0226-SM-2XCDS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952661
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10489
CTCF_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.985453
GTEX-SSA3-0008-SM-47JWJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16563
SCL-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MTF2-20144788-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
supporting cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.232881
GTEX-WFON-0001-SM-3P61W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05974
Volasertib_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0318052
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE153189_2_v_3_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7382-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE216273,GSE216292_0_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lateral ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NUS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.70632
Crus 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18342
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10489
PAPLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3694
Obsessive-compulsive disorder or autism spectrum disorder	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.539794
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.879848
SUM185PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.849898
Sarcoma_SARC_TCGA-WK-A8XQ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE168097_3_v_2_epinephrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_14982_KO_Setd1a_SRP330236	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.00442
Congenital nervous system abnormality	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.292
Lung adenocarcinoma_LUAD_TCGA-86-A4P8-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE85880,GSE85881_4_v_2_tretinoin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE231720,GSE231724_3_v_0_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Everolimus_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0385789
GSE221020,GSE221023_2_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Blastoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.866
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10489
hsa-miR-1910	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Perturb_13929_KD_NBAT1_SRP221510	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
SKNO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70202
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14834
egg	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.160579
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54315
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12173
GSE125014_1_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
YAP1-20516196-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
JHUEM1	DepMap CRISPR Gene Dependency	1.0	3.12196
artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04646
auditory vesicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.22425
Medial amygdalar nucleus, posterodorsal part, sublayer b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.99618
ChIP_RNF2_16625203	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7331-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100330_PCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.64271
NCI-H1793	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE217115_2_v_0_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
20460173-ImmPortComprehensiveListofImmune-RelatedGenes	GeneSigDB Published Gene Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.876512
BI-78D3_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0243276
GSE85880,GSE85881_0_v_2_tretinoin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HS840T	CCLE Cell Line Gene Expression Profiles	1.0	1.47897
GTEX-WXYG-2226-SM-4E3IM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872412
GSE135439_0_v_1_pax5_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9232687-13238_2021_887_MOESM3_ESM.xlsx-37_KD_sgCDC20_vs_sgNTC-Differentially_expressed_genes_DEGs_upon_CDC20_knockdown_under_37_culture_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10489
GSE118766_1_v_0_ifng_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Postsynaptic endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.054
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.25168
Perturb_12158_KD_LIN28A1_SRP061243	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.12231
Perturb_5566_KO_Sorbs2_SRP221026	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.52133
GSE205163,GSE205164_1_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMARCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45685
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06127
GSE84462,GSE84762_0_v_7_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1428	COSMIC Cell Line Gene Mutation Profiles	1.0	null
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-0.721964
GSE171401_1_v_0_adnp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216043_7_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
AGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3606
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
GTEX-XMD1-0011-R11A-SM-4AT5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843149
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE235701,GSE261434_0_v_1_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-P4QR-0426-SM-2S1NV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1437
GTEX-XUYS-0008-SM-47JYZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18179
vitamin c_mus musculus_gpl6246_gse19378	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-S4Z8-0008-SM-33HAZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82208
primary visual cortex (striate cortex, area V1/17)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.898682
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5470-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
m1AD (DM) part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55551
Breast	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7245-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Thalidomide-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
Perturb_6374_KD_COP1_SRP073333	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.3187
Colorectum	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE246911,GSE246913_4_v_1_arid1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE224311_3_v_2_chaetocin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.048
PKBalpha_KO_GDS1784_196_mouse_Embryonic fibroblasts (MEFs) - 24h	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10489
GSE239457_1_v_0_rasa1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.981741
EEF1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	9.0061
CLPP_KO_GDS4791_375_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GP5D	DepMap CRISPR Gene Dependency	1.0	4.86314
GSE145171_0_v_1_prox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158431_5_v_4_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ChIP_H3K27me3_17603471_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
TAL1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.86246
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.43451
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19D-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158182_5_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854434
GSE151829,GSE151831_5_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Heart Defects, Congenital	CTD Gene-Disease Associations	1.0	1.37275
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-REY6-1226-SM-48FDR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857282
ARNT-22903824-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC11615365-41467_2024_54246_MOESM4_ESM.xlsx-RT4-Numb-KD_vs_Ctr-KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-3941	TargetScan Predicted Conserved microRNA Targets	1.0	0.37496
VMCUB1	DepMap CRISPR Gene Dependency	1.0	2.76868
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
inner CP in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0003
decreased total tissue mass	MPO Gene-Phenotype Associations	1.0	null
GTEX-R55F-1426-SM-2TF53	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24145
ATG16L2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-Q2AI-1426-SM-2S1P5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879611
GSE189653,GSE203344_5_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE172016_2_v_0_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE95386_0_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X62O-0008-SM-46MU5	GTEx Tissue Sample Gene Expression Profiles	1.0	2.18707
Sarcoma_SARC_TCGA-KD-A5QS-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BMI1-23680149-NPCS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
GTEX-S95S-0008-SM-4AT5M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94027
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-548l	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GSE210101,GSE210114_7_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE178255_2_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE164757,GSE164759_1_v_0_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MBD3-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
AURKB_knockdown_92_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.56368
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE226249_0_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE138863_2_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE118617,GSE118619_0_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superior parietal lobule, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.32308
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.981741
H3K4me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.9312
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10834
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9112
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-O5YV-0008-SM-4E3HP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22547
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057391
TMOD3_KO_GDS4827_415_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me3_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
foot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.451428
GTEX-O5YT-0226-SM-32PK5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829614
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.827
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15941
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.887034
GTEX-QDVJ-0008-SM-48U2E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57321
GSE214823,GSE214824_0_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135705_5_v_3_corticosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12619835-41467_2025_66007_MOESM13_ESM.xlsx-Sheet1-Basal_like_KLF5_peaks_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-SNU-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE176008_7_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_fibroblast of pedal digit skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDT8-0426-SM-32PKZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987364
metabolic	GAD High Level Gene-Disease Associations	1.0	0.293278
GTEX-WFJO-0008-SM-4LVN7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20739
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.0
HOXB9_02_15	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.45943
anterior (rostral) cingulate (medial prefrontal) cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02032
YY1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1838	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
intermediate stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08134
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35475
PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_6_MRC-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.160053
hsa-miR-3910	TargetScan Predicted Conserved microRNA Targets	1.0	0.059817
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0635
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.472
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
neural tube	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.67821
KLF4-25985364-ATHEROSCLEROSIS-LESION-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWS6-0008-SM-47JYV	GTEx Tissue Sample Gene Expression Profiles	1.0	2.41568
GSE213588_10_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.545
anterior part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.82759
PMC11214527-mmc5.xlsx-TP53-gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Leydig precursor cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
H3K79me2_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_16434_KD_APP_SRP187586	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GSE181966_0_v_3_has2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE111035,GSE111040_8_v_5_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4531812-13058_2015_618_MOESM11_ESM.xlsx-Metabric_Sparse_KM_976-TFAP2B_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pralsetinib_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0319139
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53918
GSE197850_4_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-488	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
GTEX-XBEC-0008-SM-4AT3X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29218
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17197
GSE139540_4_v_1_menadione_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF-31629814-HEPATOCYTES-MOUSE-TYROSINEMIA	ChEA Transcription Factor Targets 2022	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JT-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4113
GSE145215_0_v_3_krt13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-371-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
SKNAS	CCLE Cell Line Gene CNV Profiles	1.0	1.80953
20622163-TableS2	GeneSigDB Published Gene Signatures	1.0	null
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39687
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20322
GSE124471,GSE124488_2_v_3_lats1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7315-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6452
caudal presubiculum (postsubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23579
GTEX-W5X1-1426-SM-3GIKH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23909
GSE229671,GSE229673_3_v_1_yrdc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE242083,GSE242098_2_v_5_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE242199_2_v_11_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TMEM208	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06623
RBM17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02571
calcium ion binding	GO Molecular Function Annotations 2015	1.0	null
GSE233679_12_v_11_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
TLE5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0572
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE125219,GSE125221_5_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
posterior hypothalamic area, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17088
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.48555
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0731
hsa-miR-4321	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
peduncular nucleus of the stria medullaris	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5288
GSE138001_5_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042888
SH3GLB1	Pathway Commons Protein-Protein Interactions	1.0	null
primary motor cortex (area M1, area 4)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.28057
Lung adenocarcinoma_LUAD_TCGA-44-6777-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_EC_PSc_vs_NB_2D_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Chlorophenamine-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.06445
AMO1	DepMap CRISPR Gene Dependency	1.0	7.24982
PMC10967149-12903_2024_4167_MOESM3_ESM.xlsx-LPS_VS_LPS_PDLSC-CM_776-Gene_symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SIU8-0008-SM-4BRUC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3195
GSE138818_1_v_0_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
SIN3A_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.995265
GSE182680,GSE182683_10_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
ventrolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13
Adrenocortical carcinoma_ACC_TCGA-OR-A5J8-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE178255_5_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE209582_1_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
terminal paraventricular area of THyA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10189
SCH	DepMap CRISPR Gene Dependency	1.0	2.3687
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4770-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE48812_3_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100372_HIP_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.47003
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01117
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17528
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40962
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059153
GSE185944_5_v_4_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE173810_0_v_1_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XQ3S-0008-SM-4GIDZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86579
Medial amygdalar nucleus, anterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35212
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10489
Pexidartinib (hydrochloride)_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0326983
SET2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Rough endoplasmic reticulum membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.889
YMB-1-E	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-455-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-0.865447
Mesopallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.583
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884357
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7397-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE152055_0_v_1_mpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Atrial heart septal defect	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.179
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14738
superficial stratum of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20677
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_SUZ12_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
MZ in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38985
B-lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	4.217
HLE	CCLE Cell Line Gene CNV Profiles	1.0	1.6712
GSE48812_4_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
layer VI of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.03936
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19052
GSE226983_2_v_0_ddx5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE164757,GSE164759_4_v_3_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CABIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01379
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE140997_10_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HS695T	DepMap CRISPR Gene Dependency	1.0	2.7989
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.948333
GSE118766_2_v_3_ifng_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12621392-12864_2025_12212_MOESM2_ESM.xlsx-GSF-F_48h_2-up-regulated_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
Breast Cancer_Mammary Gland Tissue_GSE1379	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.80311
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE205163,GSE205164_2_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Nanog	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.645
hsa-miR-1273g	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Tonsil	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-U3ZH-0008-SM-4DXT2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88455
GSE92589_0_v_1_sirolimus_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
KMS-28BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.835746
hsa-miR-4802-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GSE174498,GSE174500_5_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Sarcoma_SARC_TCGA-IW-A3M4-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central part of CEl	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23425
SUZ12-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-SSA3-0226-SM-32QPN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.959895
HS888T	CCLE Cell Line Gene Expression Profiles	1.0	1.54337
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052674
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.29195
AZD1390_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0118791
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WEY5-0008-SM-4LMKC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44504
Perturb_2265_KO_RACK7_SRP223446	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.911151
GSE142210_3_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.80785
nfe2l2_23639809_whole_esophagus_lof_mouse_gpl7202_gse39629	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.01463
adipose tissue	GTEx Tissue Gene Expression Profiles	1.0	0.857695
hsa-miR-33b	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
Ascl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.5989
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.912865
GSE226249_5_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF718	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41182
r1 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06623
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
plant form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057608
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4QT-0226-SM-3LK68	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890369
Perturb_2858_Mut_BRAF_SRP404927	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
SK-MEL-24	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ARHGEF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22653
GSE154767_4_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XV7Q-1726-SM-4BRUU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925398
GSE210870_0_v_1_snai1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE117730,GSE117732_0_v_2_apobec2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ5-1826-SM-3NB22	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860249
Liver hepatocellular carcinoma_LIHC_TCGA-5R-AA1D-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11696420-41467_2024_55617_MOESM3_ESM.xlsx-Sheet1-Supplementary_Data_1_The_2495_differentially_expressed_genes_between_the_L3MBTL3_knockout_L3-KO4_or_L3-KO5_and_control_C_groups_of_SUM159PT_cells_L3MBTL3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PVOW-0008-SM-48TE8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77541
GSE228181_4_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XMK1-0001-SM-4B64F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.956468
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24077
KYSE-150	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE152699,GSE152723_0_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PK-45P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0839
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
Cadherin signaling pathway	PANTHER Pathways	1.0	null
cSARS Bat SRBD_48Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.84191
HUP-T3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03826
mRNA_SFPI1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0251
BTN3A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05851
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE147834_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
periventricular stratum of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54266
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12288
TMOD3_KO_GDS4827_39_mouse_fetal liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A8HJ-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
H3K4me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EGR1	ENCODE Transcription Factor Targets	1.0	null
GSE101112_0_v_4_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MZ in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.859174
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68106
single-organism process	GO Biological Process Annotations 2015	1.0	null
Nervous System Diseases	CTD Gene-Disease Associations	1.0	1.20913
EHF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2577
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051152
GSE77108_6_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.88869
Autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.114
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW620	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59001
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Neoplasms	CTD Gene-Disease Associations	1.0	1.01137
CLPP_KO_GDS4791_106_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
TCFCP2L1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
induseum griseum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08911
PMC8755441-mmc3.xlsx-IRF1-UP-mono_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-891b	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
GTEX-WH7G-0008-SM-4LVNM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43456
Lung adenocarcinoma_LUAD_TCGA-44-2655-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OAW-42	COSMIC Cell Line Gene Mutation Profiles	1.0	null
amygdaloid complex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1196
GSE206516,GSE206518_1_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE100464,GSE100465_1_v_3_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
inner CP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02838
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.15032
GTEX-UPK5-0003-SM-3NMDI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26397
hsa-miR-135a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54301
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5989-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30449
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
PMC5263239-mmc2.xls-SEM_siMLL-AF4-MLL-AF4_gene_targets_with_increase_in_MLL-AF4_ChIP-seq_signal_371_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GATA3	ENCODE Transcription Factor Targets	1.0	null
GABPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5766
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.40258
mRNA_ASCL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GSE178714_5_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9385264-NIHMS1828071-supplement-8.xlsx-AR-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XV7Q-2626-SM-4BRVA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23916
pineal gland	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.59074
Acute Myeloid Leukemia_LAML_TCGA-AB-2980-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00456
JUND	ENCODE Transcription Factor Targets	1.0	null
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14217
MZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.870744
GTEX-S95S-0002-SM-3NM8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.989631
Adenine_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0186839
MG-63	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE179693,GSE179694_4_v_2_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Glottis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.86
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.930344
Retinopathy in non-diabetics	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.530103
GSE142210_3_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10489
ABI2	Pathway Commons Protein-Protein Interactions	1.0	null
pancreas	GTEx Tissue Gene Expression Profiles	-1.0	-0.847317
RUNX2	ChEA Transcription Factor Targets	1.0	null
spleen	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CTCF_fibroblast of pedal digit skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
spiral organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.392686
SP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.67858
GTEX-W5WG-0002-SM-3NMDN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889408
SOX9-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YN-11A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1264	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
hsa-miR-676	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
T98G	CCLE Cell Line Gene Expression Profiles	1.0	1.47031
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.853833
GSE242199_2_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148692,GSE148695_7_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_8677_KD_KLF11_SRP044756	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.46737
GTEX-UJHI-0008-SM-4IHL1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6468
GSE214823,GSE214824_4_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4686761-ncomms10068-s3.xlsx-S2G-MSC_down_specific-Supplementary_Data_2G_-_expression_of_down-regulated_genes_2_fold_change_specifically_in_MSC_PTEN-_-_vs_MSC_PTEN_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64407
Lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	4.217
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9158
GTEX-UJHI-1626-SM-3DB9A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05517
GTEX-PLZ4-0008-SM-48TE6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24681
ZMYM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36203
PMC9377669-tx1c00392_si_002.xlsx-Magnesium_Cl-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
SNU739	DepMap CRISPR Gene Dependency	1.0	5.3464
GSE218580_1_v_0_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE106661,GSE106665_2_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
WERIRB1	DepMap CRISPR Gene Dependency	1.0	4.2105
19168792-TableS3	GeneSigDB Published Gene Signatures	1.0	null
Perturb_14783_KO_Mof_SRP225948	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.60554
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_17048_KD_BATF3_SRP230607	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.10686
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.06445
colon	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SNAPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51148
GTEX-XYKS-1826-SM-4E3JV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91118
hsa-miR-4652-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
PMC5787244-13229_2018_191_MOESM1_ESM.xlsx-FOXO1_GSEA_txt-GENE_SYMBOL_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.913198
GSE142210_11_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE111102,GSE111105_3_v_7_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE242199_6_v_7_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
periventricular stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0079
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08133
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
upper dorsal perifornical nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1889
GSE127790_9_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06171
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
interventricular septum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.630314
GSE138818_1_v_3_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135350_2_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
outer CP in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22645
ATG16L1	Pathway Commons Protein-Protein Interactions	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-F2-6879-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
LC-1-SQ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE146982_3_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28113
PMC5263239-mmc2.xls-SEM_-_MLL-AF4-Non-spreading_targets_gene_names_2497_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X5EB-0004-SM-46MWA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.970922
hsa-miR-26b	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
Myocardial Infarction	DisGeNET Gene-Disease Associations	1.0	null
Hemispheric regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09293
Human - Motor Cortex - Cluster - LAMP5+ NMBR+ Layer 1 GABAergic neuron	HuBMAP Azimuth Cell Type Annotations	1.0	null
GSE142210_9_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
lateral parabrachial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.865263
GTEX-QMRM-0008-SM-447B1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59106
GTEX-QLQ7-0008-SM-447AW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30207
hsa-miR-580	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
GSE139540_0_v_1_menadione_human	RummaGEO Drug Perturbation Signatures	1.0	null
RNF2-16625203-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_ID_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6148-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K36me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsal paracommissural tectal nucleus, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46376
TAF1_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854434
Flutamide_A-427	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0157117
Perturb_6419_KD_PTPRN_SRP322005	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
HS934T	CCLE Cell Line Gene Expression Profiles	1.0	1.39174
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854434
GSE122067_2_v_1_mtch2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.413912
mRNA_TCF7L2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CTCF_medulloblastoma_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hexylresorcinol_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0190427
PMC6754502-41598_2019_50051_MOESM3_ESM.xlsx-Br_Thermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41212
Medial amygdalar nucleus, posterodorsal part, sublayer a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.8707
intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.305226
GSE252857_1_v_0_klf15_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36856
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41601
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.948572
Ixazomib_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0173686
patent ductus arteriosus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.96918
hippocampus (hippocampal formation)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.988205
HS839T	CCLE Cell Line Gene Expression Profiles	1.0	1.78187
hsa-miR-485-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.907058
Bed nuclei of the stria terminalis, posterior division, principal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52199
Lung adenocarcinoma_LUAD_TCGA-50-5935-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain_CT2_Inh L1 LAMP5 NMBR	HuBMAP ASCT+B Annotations	1.0	null
hsa-miR-3671	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13846
wi38va13	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.616
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.857143
H3K27me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1581	CCLE Cell Line Gene Expression Profiles	1.0	1.37129
GTEX-OHPK-0008-SM-4E3JL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09938
Brain ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3365
GSE202933_1_v_0_ugt2b28_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OXRN-0226-SM-2I5EJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05869
GSE128634,GSE128636_4_v_5_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10881685-Data_Sheet_5.CSV--CASZ1_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-548c-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.056784
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE226316_3_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142210_9_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE189789_0_v_1_oridonin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Medial amygdalar nucleus, posterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75091
intermediate stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34739
GSE160373_6_v_4_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211126_3_v_4_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043282
inner CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.873268
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.945335
head of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02773
RAD21_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
17952122-GeneList	GeneSigDB Published Gene Signatures	1.0	null
BRD4_knockdown_223_GSE50865	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.59979
CTCF_LNCaP clone FGC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_ESX1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
dactinomycin_mus musculus_gpl6246_gse21233	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-6560-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-3.07352
Clotrimazole_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.026795
GSE149760_0_v_1_elof1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF780A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42018
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1143	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3323
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PHC1-16625203-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Nervous System Malformations	CTD Gene-Disease Associations	1.0	1.22534
GSE233679_14_v_8_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053936
GSE119498_0_v_10_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041144
GSE205163,GSE205164_2_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_15258_KO_Sall2_SRP171624	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Archenteron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.588
GSE238005_5_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135030_8_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE166315_2_v_4_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_fibroblast of villous mesenchyme_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7439574-13148_2020_914_MOESM2_ESM.xlsx-log2_fold_change_2-1769_genes_are_more_than_four-fold_upregulated_in_PRDM8-_-_compared_to_control_PRDM8	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U412-0008-SM-4DXTE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67715
GTEX-UPIC-0002-SM-3NMDC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30278
EZH2	ChEA Transcription Factor Targets	1.0	null
colon	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.95794
TAL1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
GSE174498,GSE174500_5_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RAP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42888
CTCF_astrocyte of the spinal cord_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE245270_1_v_5_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.062242
SUDHL6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.9281
Bone marrow	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SOX2-21211035-LN229-GBM	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_13141_KO_Ctr1_SRP165861	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.41364
PMC4165364-13059_2014_406_MOESM5_ESM.xls-Supp_Dataset_3-SUPPLEMENTARY_DATASET_3_AML3_AzaC_WIMSi_246_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
Interposed nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3719
deep gray layer of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.8677
ventral paracommissural tectal nucleus, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54622
Paraventricular hypothalamic nucleus, magnocellular division, medial magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5119
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04821
GSE216413_1_v_0_gata3_human	RummaGEO Gene Perturbation Signatures	1.0	null
SKM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Vismodegib-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6754502-41598_2019_50051_MOESM3_ESM.xlsx-Br_Heat_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
preoptic region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.975641
(R)-Verapamil (hydrochloride)_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0148869
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE233679_12_v_4_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE226249_0_v_4_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
basal nucleus of Meynert	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03741
PMC10319804-41467_2023_38747_MOESM10_ESM.xlsx-cARID1A_KD_genes_down-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10305740-pwac061_suppl_supplementary_table_s1.xlsx-FOXO3-knockout_bulk_RNA-seq-Unnamed_1_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5080-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LC-2-AD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6978-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ABITRAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36638
GSE158458_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XL-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVUS-0008-SM-447AY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39178
GSE152666,GSE152668_2_v_1_carm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TIG3TD	CCLE Cell Line Gene Expression Profiles	1.0	1.55325
arcuate nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.832925
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B8-01A-31R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-7523-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS822T	CCLE Cell Line Gene Expression Profiles	1.0	1.44626
P31FUJ	CCLE Cell Line Gene CNV Profiles	-1.0	-2.12287
TMOD3_KO_GDS4827_313_mouse_Liver erythroblast	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8419-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Sucralose-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
ATP5F1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12665
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-5318-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE194396,GSE194429_2_v_3_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142210_9_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5453-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25246
GTEX-P4PP-0008-SM-48TDV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02693
mantle zone of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26498
GTEX-PWN1-0008-SM-48TEA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76661
Piroxicam_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0164321
Declive (VI)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2273
CTCF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.1696
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052625
ABHD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34954
Nucleus y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66183
molecular_function	GO Molecular Function Annotations 2015	1.0	null
r1 part of vestibular sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14849
Mesothelioma_MESO_TCGA-SC-A6LM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.407
GSE174701_4_v_7_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
inner ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.243918
GSE205163,GSE205164_3_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HS172T	CCLE Cell Line Gene Expression Profiles	1.0	2.9297
GSE138938_1_v_2_foxp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE151083_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WYVS-0006-SM-3NMA7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18013
GSE188458_2_v_4_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intermediate white layer of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.90969
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7072-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD56+_NKCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.82577
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.56076
leg	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.153809
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.59
Prostate adenocarcinoma_PRAD_TCGA-EJ-7786-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7792-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4773	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Frontal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	5.0
GTEX-P44H-0008-SM-48TDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23211
PMC9377669-tx1c00392_si_002.xlsx-Ranitidine-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-3143	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
pyramidal layer of IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08527
COLO-783	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Septohippocampal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02283
Bed nuclei of the stria terminalis, anterior division, dorsomedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40815
16651414-Supp3	GeneSigDB Published Gene Signatures	1.0	null
u-87mg cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.907109
Gallic acid_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0147588
Perturb_5012_Mut_Sall4_ERP122174	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.1649
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13917
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854434
GSE214823,GSE214824_0_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE184356_1_v_2_tfam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S4Q7-0003-SM-3NM8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.906172
GSE154074_1_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Decreased_in_both_CSDE1_KD_hESC-hgnc_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE245270_2_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.306444
GSE158182_3_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
a431	HPA Cell Line Gene Expression Profiles	-1.0	-0.894171
skin	GTEx Tissue Gene Expression Profiles	1.0	1.38734
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06135
GSE216273,GSE216292_0_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SOX2_Deficiency_GDS4853_322_human_AZ-521 gastric cancer (GC) cell line - 24 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-7004-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TUHR14TKB	DepMap CRISPR Gene Dependency	1.0	3.23755
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intestine	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE126345_4_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01279
Perturb_5904_KD_EBNA1BP2_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.02381
Blood	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	4.217
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4386
GSE227891_2_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
substantia nigra, pars compacta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.55979
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.095
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10247733-41408_2023_863_MOESM2_ESM.pdf-375-PBX1_PBX1	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6975-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56437
GSE238018_3_v_0_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE157383_3_v_2_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HINFP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44602
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TY-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9130782-Table_3.xlsx-downregulated-ZNF366_ZNF366	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PBX3	ENCODE Transcription Factor Targets	1.0	null
GSE184892_4_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4332
GSE130081,GSE130082_0_v_10_neil2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_11608_KD_ASB15_SRP113334	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.38371
TEK_knockdown_122_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.62931
intermediate stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78471
GTEX-SNMC-0008-SM-4DM5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79789
GF1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4512-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.274394
posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.840142
Perturb_8655_KO_ESRRA/ESRRG_SRP304242	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061861
GSE233679_12_v_2_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10489
brain development	GO Biological Process Annotations 2023	1.0	null
PMC5749531-jci-128-96551-s002.xlsx-Mouse_SPOP_ERG_PTEN_Loss-Hgene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33816
hsa-miR-4643	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_3663_KD_RBM26/RBM27_SRP243927	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
CHD2	ENCODE Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VV-A86M-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H3122	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-1185	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Brain Lower Grade Glioma_LGG_TCGA-CS-6188-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE206870,GSE206872_1_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-W5X1-0008-SM-4LMKA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24259
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
GSE81803,GSE81912_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-587	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
growth/size/body phenotype	MPO Gene-Phenotype Associations	1.0	null
cervix, uterine	HPA Tissue Protein Expression Profiles	-1.0	-0.721964
Branchial arch	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.328
cerebellar cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.52508
Facial motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45239
GSE213588_8_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3MA-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4729	TargetScan Predicted Conserved microRNA Targets	1.0	0.31417
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7045-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04273
PHC1-16625203-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45284
GSE94011_0_v_3_pias3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
optic fiber layer of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01519
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06393
GSE201110_0_v_1_sirt4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158182_3_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4775	TargetScan Predicted Conserved microRNA Targets	1.0	0.119151
GSE140646_0_v_1_atf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NVP-BHG712_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.031436
GSE129241_3_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cerebellar nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.774
lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056401
GSE148692,GSE148695_2_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-P4PP-2026-SM-3P61N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91603
lung	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	3.10125
GSE113734_3_v_0_qprt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WOFL-0826-SM-3MJG1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830634
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-HAND1_neg_targets-Gene_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
SCC-9	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_3673_KO_SLC25A4_SRP372860	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GTEX-W5X1-2626-SM-4LMI8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14375
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Change_in_both_CSDE1_KD_hESCs-gene_short_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8935
Bach1::Mafk	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.2368
Precommissural nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2023
OCI-M1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE189653,GSE203344_2_v_0_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE127790_11_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cSARS Bat SRBD_60Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.34276
GSE125014_6_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Gastrula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.226
medial part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43298
GTEX-U8XE-0005-SM-3DB8I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61765
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
NFIC::TLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0
HS819T	CCLE Cell Line Gene Expression Profiles	1.0	1.51295
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7091-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11632_KD_HSPC182_SRP113334	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.18958
PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_CSc_vs_NB_2D_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.957213
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.1635
anchoring junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.272267
PMC10769395-media-2.xlsx-S2D_EF_Repressed_genes-Ebegboni_et_al_Supplemental_Table_S2D_Increased_expression_following_depletion_of_EWSR1_FLI1_TC-32_TC-71_and_A673_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3	ENCODE Transcription Factor Targets	1.0	null
GTEX-U3ZN-0726-SM-4DXT5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939952
stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.08324
mantle zone of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11221
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-5783-01A-41R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_6170_KD_PROX1_SRP073100	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.12346
mantle zone of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03199
GSE169571_0_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE216043_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Human - Motor Cortex - Cluster - VIP+ SOX11+ Layer 2-5 GABAergic neuron	HuBMAP Azimuth Cell Type Annotations	1.0	null
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_4280_KO_Smchd1_SRP134966	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.4932
Perturb_5586_KO_RELA_SRP149723	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
PEER	CCLE Cell Line Gene CNV Profiles	1.0	1.84194
GTEX-X4XX-0008-SM-46MVK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5494
PMC8390679-41467_2021_25186_MOESM5_ESM.xlsx-ISL1-Unnamed_4_ISL1	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Weight Loss	CTD Gene-Disease Associations	1.0	1.4275
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16397
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.22794
JHU011	DepMap CRISPR Gene Dependency	1.0	3.95863
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE166315_1_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE192513,GSE192515_2_v_0_atg16l1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.379875
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.0741
LUC7L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00276
GTEX-U3ZH-0002-SM-3NMDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11621
r3 part of lateral vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.1696
CTCF_brain microvascular endothelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.545
substantia nigra, pars compacta, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.73778
cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.35334
GSE233647_4_v_6_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.943506
ARNT	ChEA Transcription Factor Targets	1.0	null
Perturb_17580_KO_Rif1_SRP348198	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.69661
CTCF_retinal pigment epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_SUZ12_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE104508_2_v_3_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Medial preoptic nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00676
21152935-TableS1	GeneSigDB Published Gene Signatures	1.0	null
GSE234334,GSE234336_1_v_0_zhx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-O5YU-0008-SM-4E3I7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884457
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-HAND1_neg_targets-ID_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9950457-mmc3.xlsx-GRHL2_binding_sites-RBBP8NL_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54003
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S33H-1126-SM-2XCB6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08433
hsa-miR-4277	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
Lung squamous cell carcinoma_LUSC_TCGA-43-6770-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
precuneus, right, superior lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05889
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24877
DAB1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-S4P3-1826-SM-3K2AL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907318
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10489
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10489
IRF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5952
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-513a-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
GSE217156_1_v_3_trpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X638-0008-SM-47JZ7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95901
PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_4_FDC-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43236
TAF1_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Growth cone membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.639
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_9665_KD_TCF4_SRP188467	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
paraventricular nucleus, peduncular or principal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36263
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAJI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50051
GSE184892_6_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
Large intestine	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.834051
Fetal Growth Retardation	CTD Gene-Disease Associations	1.0	1.08055
central nervous system development	GO Biological Process Annotations 2023	1.0	null
shortened ST segment	IMPC Knockout Mouse Phenotypes	1.0	null
GSE228181_4_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
metal ion binding	GO Molecular Function Annotations 2015	1.0	null
hsa-miR-337-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-RT4-FOXA1_peaks_Context1_2-Gene_Name_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
Nucleus x	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04103
Ciclopirox_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0331817
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.7861
upper (rostral) rhombic lip_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08194
paclitaxel_homo sapiens_gpl570_gse39042	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
parastrial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43089
LXF-289	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20W-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31985
mantle zone of r4Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43693
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888918
GSE126345_2_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-NR2F2_NR2F2	Rummagene Transcription Factor Associations 2026	1.0	null
STAT3-18555785-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
19286929-SuppTable2a	GeneSigDB Published Gene Signatures	1.0	null
CTCF_astrocyte of the spinal cord_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE239844_7_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE164874_5_v_6_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2821-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6867
GATA5_KO_GSE47425_386_mouse_lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CAL27	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69988
Brain Lower Grade Glioma_LGG_TCGA-DU-7007-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_14907_KO_Pgr_ERP140354	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Cepharanthine_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0462719
Vestibular nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00953
GSE154767_2_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE225869_3_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-PLZ6-0008-SM-48TD5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11398
BICR31	DepMap CRISPR Gene Dependency	1.0	2.50079
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.48462
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.974536
hsa-miR-26a	TargetScan Predicted Conserved microRNA Targets	1.0	0.348832
PMC6932815-ppat.1007634.s015.xlsx-ST5_DGE_ELF1-R8AvIFN48-mock_lfc-ensembl_gene_id_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
NCKAP1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE140997_2_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TGBC11TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE166315_1_v_4_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE226249_2_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
stratum oriens of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05378
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4296
GSE210885_0_v_7_klf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61115
GSE213588_9_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SP in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13787
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YR-11A-13R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS618T	CCLE Cell Line Gene Expression Profiles	1.0	1.90619
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11611169-pone.0314092.s001.docx-3-PPARG_PPARG	Rummagene Transcription Factor Associations 2026	1.0	null
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-XYKS-0008-SM-4BRW6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25375
mcf7	HPA Cell Line Gene Expression Profiles	-1.0	-0.894171
Sarcoma_SARC_TCGA-MO-A47R-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GPR150	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37626
inferolateral temporal cortex (area TEv, area 20)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.894472
GSE213996_1_v_0_fhl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6190866__F6	PFOCR Pathway Figure Associations 2023	1.0	null
GSE226249_0_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE84148,GSE96938_0_v_2_nrros_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HUTU80	CCLE Cell Line Gene Expression Profiles	1.0	2.45222
hsa-miR-23c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
hippocampus (hippocampal formation)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09679
periventricular stratum of r1Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21946
postcentral gyrus, right, bank of the posterior central sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07462
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7097-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Declive (VI), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26068
GSE163240_3_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4373
Bergenin_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0294248
GSE206870,GSE206872_1_v_5_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
NCI-H720	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.27226
MXI1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCIM2	DepMap CRISPR Gene Dependency	1.0	4.88606
hsa-miR-374c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
PMC9305137-PATH-256-297-s005.xlsx-CIC_associated_DE_genes_IDH1-R-Unnamed_1_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6106
GSE186647,GSE217288_1_v_4_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE150669_2_v_3_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-SN8G-0008-SM-4DM4X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2417
hsa-miR-23b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsal motor nucleus of the vagus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.867773
dorsal part of m1A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49845
CTCF_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100653_PCx_probable Alzheimer's disease_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.32862
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	110.086
GTEX-W5X1-0006-SM-3GIJZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10489
GSE233647_4_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MZ in posterodorsal (superior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.28429
GSE176008_4_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-2053	TargetScan Predicted Conserved microRNA Targets	1.0	0.31417
PMC11839389-PUL2-15-e70058-s003.xlsx-FLF_TBX4_mergeRNAseqChIPseq-symbol_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
lymphoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053792
GTEX-QMRM-1726-SM-2S1QG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842212
Signal recognition particle receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.969
amygdaloid complex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.919728
Hearing Loss, Sensorineural	CTD Gene-Disease Associations	1.0	1.07875
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.974536
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
496100406_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.08453
Male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.047
HOXA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7374
Rectum adenocarcinoma_READ_TCGA-F5-6702-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
preweaning lethality, incomplete penetrance	IMPC Knockout Mouse Phenotypes	1.0	null
GTEX-P44H-0011-R11A-SM-2XCER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.859902
GSE225901_2_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC11615365-41467_2024_54246_MOESM4_ESM.xlsx-RT4-Numb-KD_vs_Ctr-KD-ensemblGeneId_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_astrocyte of the cerebellum_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22182
RNF2-18974828-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
mRNA_POU5F1_20526341	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PPARG-20887899-3T3-L1 PREADIPOCYTE CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
large intestine	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE242199_6_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE120370_0_v_3_thrombin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF417	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01806
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.993161
KMS21BM	CCLE Cell Line Gene CNV Profiles	1.0	2.02015
Tubulin inhibitor 6_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0587467
Perturb_6634_OE_KAT7_SRP174052	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.1031
PBX3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE96777,GSE96778_1_v_0_zbtb4_human	RummaGEO Gene Perturbation Signatures	1.0	null
primary auditory cortex (core)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.49937
GSE196104,GSE196106_2_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142210_3_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE210580_3_v_6_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WV-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5163-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148010,GSE148120_3_v_2_tet2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Fatty Liver	CTD Gene-Disease Associations	1.0	1.40953
GSE202434,GSE202438_13_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.3261
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14621
abnormal total tissue mass	MPO Gene-Phenotype Associations	1.0	null
GSE79291_1_v_2_streptozotocin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ChIP_RNF2_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05526
EGR1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8283158-mmc2.xlsx-TCF4_NPC-Gene_TCF4	Rummagene Transcription Factor Associations 2026	1.0	null
Medial amygdalar nucleus, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.23676
GSE179880_4_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8283158-mmc2.xlsx-TCF4_ChIP-symbol_TCF4	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-101	TargetScan Predicted Conserved microRNA Targets	1.0	0.32519
Rectum adenocarcinoma_READ_TCGA-AG-3732-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.93869
SCAR complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.441
GSE252857_1_v_0_prednisone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hypothalamic amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86462
RB1_KD_GSE50532_591_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC9714459-DataSheet3.xlsx-Supplement_3A-1037_elements_included_exclusively_in_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-1160_PS-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
STAT3-1855785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-RT4-FOXA1_peaks_Context1_2-Nearest_Ensembl_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
SLITRK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41106
EKVX	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BL1825 (TAOK3)	NURSA Protein Complexes	1.0	null
central gray substance of midbrain, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08976
GSE221327_5_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
P300-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
paraventricular nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30182
OVK-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7434-11A-01R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
INA6	DepMap CRISPR Gene Dependency	1.0	2.20066
lateral mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.20826
PMC9377669-tx1c00392_si_002.xlsx-TSA-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LE-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7633-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE110268_0_v_3_foxd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Methorexate-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.86108
gastrula	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.00894
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65816
Perturb_13581_OE_Trpc1_SRP291421	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11132
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CLPP_KO_GSE40207_394_mouse_Liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC3526356-supp_jem.20121387_JEM_20121387_sm.pdf-36-PAX6_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8752
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-653	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GSE169691_1_v_2_saha_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MEOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1913
NB-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36534
SUZ12-18974828-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
cell property	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069464
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-WT1_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
mRNA_NR0B1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE214823,GSE214824_3_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7941712-40478_2021_1135_MOESM12_ESM.xlsx-Table_S4D_DEG_ST-EPN-RELA-Unnamed_6_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.911151
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
r2 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00953
preopto-hypothalamic band	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03918
Acute Myeloid Leukemia_LAML_TCGA-AB-2807-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE240386,GSE242143_1_v_5_morc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
18922855-Table1	GeneSigDB Published Gene Signatures	1.0	null
r5 part of the oral Sp5 subnucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03199
GSE158182_5_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YT-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_14100_KO_ARID1A_SRP355686	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE157555,GSE157556_3_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE128844_0_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Anal canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.816
MAFK_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE130401_4_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE180185_7_v_10_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
blastodisc	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.193544
GSE196962_4_v_3_parg_human	RummaGEO Gene Perturbation Signatures	1.0	null
RNF2-27304074-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
FOXP2_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11282827-40659_2024_524_MOESM5_ESM.xlsx-MSX1-sequence_name_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.51335
CRO-AP3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE214823,GSE214824_6_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE184892_6_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE164874_5_v_3_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary motor cortex (area M1, area 4)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11966
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.0799
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01388
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE131649_4_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Feather bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.161
GSE233679_12_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ESRRG_Deficiency_GDS2811_637_mouse_Fetal heart - Heterozygous null mutant	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3N_Peaks_YAP1FAM118B_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RN64-0008-SM-48FEZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64011
CLPP_KO_GDS4791_104_mouse_testis	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WL46-0326-SM-3LK6Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05572
SNRNP200	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24322
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TJ-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5798892-41421_2017_3_MOESM7_ESM.xlsx-TM_KO_vs_WT-Supplementary_Table_S2-2_Up-_and_downregulated_genes_in_ATF6_cells_relative_to_ATF6_cells_in_the_presence_of_TM_early_passage_ATF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7581777-41419_2020_3029_MOESM6_ESM.xlsx-MNX1_ChIP-Symbol_MNX1	Rummagene Transcription Factor Associations 2026	1.0	null
SARS-CoV NSP16_Day7_None_GSE49263	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.72863
mRNA_SMAD7_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
hsa-miR-33a	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
GSE202284,GSE202289_5_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
spinal cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.119833
17660535-TableS4a	GeneSigDB Published Gene Signatures	1.0	null
HS255T	CCLE Cell Line Gene Expression Profiles	1.0	1.61301
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54505
LY2090314_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0210108
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Change_in_both_CSDE1_KD_hESCs-hgnc_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SOX9-26525672-CHIP-SEQ-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KYSE-410	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7785-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE142210_11_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SERINC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04524
GSE81193_3_v_5_irf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854434
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-CA-ID_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE154350_1_v_0_ascl2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE242199_6_v_11_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.949929
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6134-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell adhesion	GO Biological Process Annotations 2015	1.0	null
hsa-miR-340	TargetScan Predicted Conserved microRNA Targets	1.0	0.069137
pioglitazone_homo sapiens_gpl570_gds4132	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE216043_11_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE195663_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE88819_7_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lymphoid cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	4.217
patent foramen ovale	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.13543
mouth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071969
CTCF_BE2C_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
animal cap	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.824849
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.24446
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.61082
SP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0876
VIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.842912
lateral part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4477
ChIP_SUZ12_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-S33H-2426-SM-2XCB2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920009
External cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0912
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.86276
hsa-miR-4796-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GTEX-VUSG-2226-SM-4KKZO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878227
GSE180185_9_v_10_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5322933-pone.0172430.s013.xls-Pathways_MSC_Single_Basal_vs_MS-Unnamed_1_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XMD1-0008-SM-4AT41	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00924
RHOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28059
intermediate stratum of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12664
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053004
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058895
GSE119498_2_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12621392-12864_2025_12212_MOESM2_ESM.xlsx-GSF-S_72h_2-up-regulated_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cerebellum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.909856
abnormal body size	MPO Gene-Phenotype Associations	1.0	null
intermediate (interpositus) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.97503
GSE202434,GSE202438_8_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Anterior hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16834
REST_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE235066_7_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CACNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07613
GSE248045,GSE248046_6_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A57E-11A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.907058
PMC8437976-41416_2021_1470_MOESM2_ESM.xls-List_of_MAF_in_SNP_Rectum-Hugo_Symbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06702
NFKB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23926
SG in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33874
GSE135705_5_v_1_corticosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE226249_2_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QEL4-0008-SM-447AZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65892
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.6551
GSE146074_10_v_3_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.853862
Hippocampus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CTCF_fibroblast of lung_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE114690_1_v_0_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWCY-2126-SM-48TEC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972438
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LN340	CCLE Cell Line Gene Expression Profiles	1.0	1.44028
GSE201217_2_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146982_7_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.09
OLIG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8697
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53508
glioblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.656648
UBTF_02_56	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.45943
mantle zone of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0384
GSE193282_2_v_0_cd44_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE178255_2_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hydrocortisone_homo sapiens_gpl570_normal scar_gds3071	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25202
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.960476
endometrium	HPA Tissue Gene Expression Profiles	1.0	0.860422
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.974536
Fetallung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55362
MDAMB134VI	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.886566
GSE128634,GSE128636_1_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXP1_01_209	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59401
TCP10L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66612
GSE126345_7_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC3962334-pone.0088950.s001.pdf-25-STAT5B_STAT5B	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial amygdala, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.62781
Perturb_10185_KD_ARNT1/3_SRP337185	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.8733
dexamethasone_homo sapiens_gpl6480_gds3946	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
mRNA_ATF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Perturb_13820_KO_Bmi1_SRP237434	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.76021
GSE151090_5_v_3_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE152699,GSE152723_3_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Medication use (beta blocking agents)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.9
lateral subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14342
GTEX-WEY5-0001-SM-3P61Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21888
Perturb_2851_Mut_NRAS_SRP404927	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
SIN3A_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193999,GSE194000_3_v_2_atf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3M_Peaks_YAP1MAMLD1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NL3H-0008-SM-4E3HU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20123
GSE207978_1_v_0_rai1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BT549	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.02207
hsa-miR-4766-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GSE238018_3_v_2_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE201042_2_v_4_ptpmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
PHC1	ChEA Transcription Factor Targets	1.0	null
r4 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1212
single-organism developmental process	GO Biological Process Annotations 2015	1.0	null
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE229973_3_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PPARD	ChEA Transcription Factor Targets	1.0	null
GSE97278,GSE97280_2_v_1_nsd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE214382,GSE214383_4_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TML8-0008-SM-4DXUI	GTEx Tissue Sample Gene Expression Profiles	1.0	2.31745
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14431
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4355-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATG3	Pathway Commons Protein-Protein Interactions	1.0	null
Cortical amygdalar area, posterior part, lateral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23199
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cerebellar nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51772
C-33-A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3R3-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.62381
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0934
superficial stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11584
GTEX-P4PQ-0008-SM-48TDX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05444
hsa-miR-138	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GSE245270_2_v_5_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE229671,GSE229673_0_v_1_yrdc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_6026_KD_KAP1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.70709
disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.205585
CSNK2A2	Pathway Commons Protein-Protein Interactions	1.0	null
Vocal fold	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.886
HF-91-IU60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.501738
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.7873
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-3923-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7566571-supp_075176.120_Supplemental_Tables.xlsx-Supplemental_Table_S9-Down_in_MSC_chond_1_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TML8-0001-SM-3NMAF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47263
GSE163240_3_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
immune	GAD High Level Gene-Disease Associations	1.0	0.293278
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-downregulated_in_ATF4OE-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
r4 part of vestibular sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43693
GTEX-QCQG-1326-SM-48U24	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826501
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10489
r4 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21265
USF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPDEF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15437
CEP170	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0519
PMC4858740-ncomms11473-s2.xls-HAdV-D9_Cr1b_Library_2-Hit_name_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE235066_4_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE242199_9_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
u138mg	HPA Cell Line Gene Expression Profiles	1.0	1.22476
Brain Lower Grade Glioma_LGG_TCGA-HT-8563-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_6087_KD_XRN2_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.698
GSE233679_14_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC5787244-13229_2018_191_MOESM1_ESM.xlsx-FOXO1_GSEA_txt-PROBE_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.545
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2129
cerebellar cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.19623
GTEX-QLQW-1326-SM-2S1QS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832166
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-11A-13R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF391	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0465
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9362
PMC5263239-mmc2.xls-SEM_-_MLL-AF4-All_targets_genes_names_2597_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
496100579_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.40676
GSE102505_4_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE227891_5_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S4Q7-1626-SM-3K2AE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858442
GSE164874_5_v_14_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Human - Motor Cortex - Cluster - SST+ DEFB108B+ Layer 1 GABAergic neuron	HuBMAP Azimuth Cell Type Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-5645-11A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934072
PMC12611713-Table2.xlsx-Sheet_1-Training_Database_AND_Validation_Database_NOT_Diabetes_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Neoplasms	CTD Gene-Disease Associations	1.0	1.06987
Uterine Carcinosarcoma_UCS_TCGA-NA-A4R1-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_17397_KO_Ring1_SRP321271	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.61743
branchial arch	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.61578
cisplatin_mus musculus_gpl339_gse6206	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-SE5C-0008-SM-4B64J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51208
CLPP_KO_GDS4791_539_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
craniofacial-deafness-hand syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.653
SG in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.3102
GSE146982_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-SSA3-0002-SM-3P61R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44187
PMC12661646-dmm-18-052290-TableS8.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
Adagrasib_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0357976
posterior paraventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0915
U266B1	CCLE Cell Line Gene CNV Profiles	1.0	1.91961
GTEX-QDT8-0006-SM-32PL3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889024
GSE152050,GSE152052_1_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20387
GTEX-RVPU-2326-SM-2TF6R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847405
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3009
persistence of hyaloid vascular system	MGI Mouse Phenotype Associations 2023	1.0	null
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.50011
MZ in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19804
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.40471
GTEX-XUYS-0005-SM-47JZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1018
posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.52219
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9585487-NIHMS1838959-supplement-4.xlsx-FOXC1-bound_downregulated-Table_S3_FOXC1_regulated_genes_FOXC1	Rummagene Transcription Factor Associations 2026	1.0	null
HUP-T4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE214596,GSE214598_1_v_4_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.0027
PMC5735185-41467_2017_1200_MOESM4_ESM.xlsx-Table_S1-Choi_et_al_2016_DUX4_up-regulated_targets_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142210_9_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216043_11_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE214931_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08468
FOXA1-33576154-HUMAN-LUNG-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
GSE205163,GSE205164_5_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
rostral division of VL	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.54939
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_6615_OE_MATR3_SRP132715	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.58777
HOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3936
PMC12540438-Data_Sheet_1.PDF-20-ZNF527_ZNF527	Rummagene Transcription Factor Associations 2026	1.0	null
KDM5A	ENCODE Transcription Factor Targets	1.0	null
GSE135030_11_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Photoreceptor distal connecting cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.82
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.15399
GTEX-P78B-0008-SM-48TE1	GTEx Tissue Sample Gene Expression Profiles	1.0	2.18923
GSE194358,GSE194361_0_v_1_kdm5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11033585-BLOOD_BLD-2023-021752-mmc2.xlsx-S11_DGEA_CDKN2A_PAX5-Supplemental_Table_11_Differentially_expressed_genes_between_CDKN2A_PAX5_and_all_other_subcluster_PAX5	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QXCU-0008-SM-48FCH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.959673
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mantle zone of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08604
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13826
GSE233679_5_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mantle zone of AHy	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86612
ChIP_SOX17_20123909	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
hsa-miR-3714	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GTEX-VUSG-2426-SM-4KKZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14963
GSE189653,GSE203344_2_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Famotidine-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7726-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bed nuclei of the stria terminalis, anterior division, ventral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36554
WDR82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19942
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE226249_5_v_6_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158431_5_v_7_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE87404,GSE87812_2_v_3_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10282096-41467_2023_39038_MOESM4_ESM.xlsx-All_genes_Upregulated-ENSG00000177426_TGIF1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Atrovastatin-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-DPH-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_10184_KD_ARNT1_SRP337185	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.9108
GSE96641_5_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WFG8-0001-SM-4LVN8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52355
GSE244072_10_v_8_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE100102_0_v_3_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QCQG-0008-SM-48U2G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952328
GSE169571_5_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
496100307_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.2415
Micronuclei, Chromosome-Defective	CTD Gene-Disease Associations	1.0	1.05237
17724462-TableS2	GeneSigDB Published Gene Signatures	1.0	null
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.22793
GSE146612_1_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K029AX	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4867
170MGBA	DepMap CRISPR Gene Dependency	1.0	4.63445
RNF2	ChEA Transcription Factor Targets	1.0	null
RIOK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61071
mRNA_RXRA_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GSE81803,GSE81912_2_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsolateral part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55731
homophilic cell adhesion via plasma membrane adhesion molecules	GO Biological Process Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-R8-A6YH-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
943 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.852
GSE216043_3_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE174498,GSE174500_5_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of r5Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43449
GTEX-XMK1-0926-SM-4B66X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867479
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.09634
telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.472315
SUM149PT	DepMap CRISPR Gene Dependency	1.0	2.15646
GSE197850_4_v_2_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
WM1799	DepMap CRISPR Gene Dependency	1.0	2.58532
EZH2-18974828-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE142210_3_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE203308_14_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
brain cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.643669
Grey cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.835
GSE151090_0_v_1_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
lateral ventricle	HPA Tissue Protein Expression Profiles	-1.0	-0.721964
Prostate adenocarcinoma_PRAD_TCGA-H9-A6BX-01A-31R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.907334
GSE256181_2_v_0_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06488
Cadherin-like	InterPro Predicted Protein Domain Annotations	1.0	null
CHK1_KD_GSE54267_671_human_U2OS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me1_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A172	DepMap CRISPR Gene Dependency	1.0	5.54593
GSE202434,GSE202438_12_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T6MO-1526-SM-4DM57	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03197
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.404
superficial stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03199
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NA-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33677
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-7_DEGs_USF2-KO_vs_control-Gene_Symbol_USF2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar nuclei of CbV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36281
GSE168171,GSE168173_0_v_1_ddx41_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X5EB-0008-SM-46MU3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27737
Triglyceride levels x short total sleep time interaction (2df test)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.9
GSE173810_0_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T6MO-0008-SM-4DM6T	GTEx Tissue Sample Gene Expression Profiles	1.0	2.03299
Ropivacaine (hydrochloride monohydrate)_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0452644
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10489
hsa-miR-4654	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05147
Lung adenocarcinoma_LUAD_TCGA-97-8174-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
glioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.460305
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.42473
GSE198165,GSE198166_6_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE233679_5_v_8_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-SHOX2_SHOX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE180200,GSE180201_12_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE131161_1_v_0_rarres1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE153189_1_v_3_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_9219_KO_Mecp2_SRP056141	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-14.855
Bentamapimod_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0464046
GTEX-WFON-1726-SM-4LVMQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827596
GTEX-S7SF-0008-SM-3NM8T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29589
SMARCE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42163
GSE122101,GSE122103_0_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142210_2_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.463013
GSE214596,GSE214598_1_v_0_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26128
Perturb_12701_KO_Anxa5_SRP379319	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.11001
GSE176093_2_v_3_mineral oil_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35798
OLIG2-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19142
NKX6-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3816
GSE217405_0_v_1_osimertinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7566571-supp_075176.120_Supplemental_Tables.xlsx-Supplemental_Table_S9-DOWN_in_MSC_chondrogenesis_420_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
pineal_day	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.05964
mantle zone of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38681
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE176008_7_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-5396-01A-02R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_14101_KO_ARID1A_SRP355686	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEY	DepMap CRISPR Gene Dependency	1.0	2.40159
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4696-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_epithelial cell of esophagus_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE248045,GSE248046_6_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Memory Disorders	CTD Gene-Disease Associations	1.0	1.36848
SUZ12-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Capivasertib_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0399172
outer SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01804
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE112714_2_v_0_ctnnb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135352_0_v_1_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POU5F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30473
H3K9me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
germ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.35743
GTEX-VUSG-1426-SM-3GIJN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29536
cell-cell adhesion	GO Biological Process Annotations 2015	1.0	null
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3692	TargetScan Predicted Conserved microRNA Targets	1.0	0.034317
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.948081
Perturb_7964_OE_GATA2_SRP167936	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE226249_2_v_3_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XUJ4-0008-SM-4BOQI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63594
GSE210911_1_v_0_crem_human	RummaGEO Gene Perturbation Signatures	-1.0	null
IRF1	ChEA Transcription Factor Targets	1.0	null
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-1.03732
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.91301
GSE158431_2_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75535
RCC10RGB	CCLE Cell Line Gene Expression Profiles	-1.0	-1.7509
GSE202434,GSE202438_4_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6853
layer IIIb of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29324
GSE196962_4_v_1_parg_human	RummaGEO Gene Perturbation Signatures	1.0	null
b19	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.55
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE96641_1_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Calcium	HMDB Metabolites of Enzymes	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8339-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MZ in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23104
GTEX-R55C-1626-SM-48FEG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891146
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42533
PMC5322933-pone.0172430.s013.xls-Oncopath_MSC_Single_Basal_vs_MS-Unnamed_1_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
ACOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08055
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-A4D9-01B-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193258,GSE193259_2_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
rostral division of OFCi (area 11)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13982
shortened QT interval	IMPC Knockout Mouse Phenotypes	1.0	null
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213588_9_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
posterior part of anterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05089
SQ1	CCLE Cell Line Gene CNV Profiles	1.0	1.53088
GSE109565_12_v_11_glyphosate_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
UBE2M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36843
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55366
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hydrocephalus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.631991
hl60	HPA Cell Line Gene Expression Profiles	-1.0	-0.894171
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.444
tuberomammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.254
PMC10742386-pnas.2311372120.sd05.xlsx-GCM1_EVT-Gene_Symbol_GCM1	Rummagene Transcription Factor Associations 2026	1.0	null
Parkin_OE_GDS4476_55_human_U87MG	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14183
Brain Lower Grade Glioma_LGG_TCGA-FG-7634-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
PMC4051124-1471-2164-15-256-S16.XLSX-WES_IPD-RBCK1_2-Target_RBCK1	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1648	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE214931_3_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QV44-0008-SM-447AX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5445
Medial amygdalar nucleus, posterodorsal part, sublayer c	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43914
Sarcoma_SARC_TCGA-KD-A5QT-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
parvicellular part of Lat	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00708
PPARG	ChEA Transcription Factor Targets	1.0	null
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TECPR1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE173307,GSE173391_0_v_1_rgcc_human	RummaGEO Gene Perturbation Signatures	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
Perturb_5952_KD_RBM15_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.08074
PMC10353540-Table_1.xlsx-HCC1954_AR_vs_HCC1954_A-Gene_Name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.105
PF-06260933_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.016524
Lung squamous cell carcinoma_LUSC_TCGA-22-5482-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ERBB2	Pathway Commons Protein-Protein Interactions	1.0	null
Sarcoma_SARC_TCGA-FX-A2QS-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_5010_KO_Sall4_ERP122174	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Lung adenocarcinoma_LUAD_TCGA-91-6830-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.97909
PMC8567138-Table_2.xlsx-Sheet1-IGFBP5_AND_IGFBP7_NOT_IGFBP3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE135244_0_v_1_trdmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CAL-33	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE198165,GSE198166_7_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FLO-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IGKV1-5	Pathway Commons Protein-Protein Interactions	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.44839
daudi	HPA Cell Line Gene Expression Profiles	-1.0	-0.894171
GSE242199_9_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100284_FWM_probable Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.17323
Adverse response to radiation therapy	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.6
hsa-miR-4453	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
brain cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.485935
TE-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OIZG-0008-SM-4E3J2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21292
TRIM28_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q734-1826-SM-2I3EL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04364
GSE245270_1_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE96991,GSE97117_5_v_2_il11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10489
superficial stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16805
GSE216043_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cerebellar nuclei of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78949
PMC5550886-cddis2017345x3.xlsx-siRAD21_DEGs_NOT_rescued_by_Myc-Unnamed_1_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_8956_KO_RB1_SRP220467	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-17.8477
GSE235066_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC3419980-leu201249x2.xls-RUNX1-ETO_siRE_ChIPSeq_peaks_ge-gene_name_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_8909_KD_CCDC144NLAS1_SRP135858	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.868927
FOXM1-26100407-CHIP-SEQ-HEK293-FLP-IN-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE216043_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BARX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1254
r5 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30257
CTCF_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.87924
Lung adenocarcinoma_LUAD_TCGA-44-7661-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100500_PCx_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.55035
SRSF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32176
Leukemia, Acute Megakaryocytic_Megakaryocyte_GSE2433	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.80141
Superior colliculus, motor related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16267
GSE233679_5_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Disease Models, Animal	CTD Gene-Disease Associations	1.0	1.29072
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38003
GSE202434,GSE202438_6_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8208823-mmc2.xlsx-CDX2-KO_mesenchymal_DEG-feature_CDX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE217405_3_v_2_osimertinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CLPP_KO_GSE40207_392_mouse_Testis	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE248858_4_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907499
PA-TU-8988S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854434
amygdaloid complex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.962178
GSE199899_4_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_13378_KD_SFRP2_SRP115559	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.5003
GSE150055_0_v_1_melphalan_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EP300_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5195898-NIHMS825571-supplement-3.xlsx-Sheet1-H1975_M1_vs_H1975_M1_CIC_reconstitution_Differential_gene_expression_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
PWP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03851
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Artery disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.545
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE213588_10_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE233679_14_v_13_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_11576_KO_Zip8_SRP344283	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.69357
inner CP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.880294
GSE193351_4_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.900942
hsa-miR-34b	TargetScan Predicted Conserved microRNA Targets	1.0	0.293524
CLPP_KO_GSE40207_388_mouse_testis	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Cerebral lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
respiratory system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	3.10125
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TKQ1-0003-SM-3NMAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.932198
GTEX-W5WG-0008-SM-4KL25	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65425
Nkx3-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.5448
GTEX-WHWD-0826-SM-3LK6R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995348
GSE135350_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
heart	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066886
GSE169571_3_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE142210_11_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HNF4A	JASPAR Predicted Transcription Factor Targets	1.0	null
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.48728
Liver Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
GSE148263_6_v_0_trim3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169334,GSE169336_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE164757,GSE164759_4_v_0_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Protocadherin-mediated cell adhesion and signaling	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
LN18	CCLE Cell Line Gene Expression Profiles	1.0	1.64736
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Tek	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.13
Pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
hippocampus (hippocampal formation)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.275
17430594-table4	GeneSigDB Published Gene Signatures	1.0	null
GTEX-QDVN-0008-SM-48U2D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4683
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8487
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Nearest_Ensembl_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
Human - Motor Cortex - Cross-Species Cluster - Vip+ GABAergic neuron_4	HuBMAP Azimuth Cell Type Annotations	1.0	null
TAF15-26573619-CHIP-SEQ-HEK293-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-607	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
GSE216043_11_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
astrocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.551686
Perturb_8995_KO_RGCC_SRP316360	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.6199
decreased body weight	MPO Gene-Phenotype Associations	1.0	null
GSE216273,GSE216292_0_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.904265
18707017-Table1	GeneSigDB Published Gene Signatures	1.0	null
Ahr::Arnt	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.375
GSE225869_2_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U3ZN-0008-SM-4DXTL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72937
REST	ENCODE Transcription Factor Targets	1.0	null
Perturb_5009_Mut_Sall4_ERP122174	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.95491
Premature Birth	CTD Gene-Disease Associations	1.0	1.25776
GSE207787_3_v_2_pdha1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.74923
PRDM16_DEPLETION_GDS4021_460_mouse_WAT - white adipose tissue (stromal-vascular cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-PX3G-0006-SM-33HBQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887093
EED-16625203-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7162-01A-21R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935421
Perturb_12689_KO_Rap1_SRP169501	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
ChIP_EED_16625203	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
MAFK	ENCODE Transcription Factor Targets	1.0	null
GSE133213_2_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LN382	CCLE Cell Line Gene Expression Profiles	1.0	2.10929
t-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.084595
PMC6347712-pnas.1812449116.sd06.xlsx-iPSC_IRF7_48h_rest_RNAExpress-Gene_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
UMC-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE135030_3_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ANO8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35919
Leukocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	4.217
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33509
GTEX-PX3G-0226-SM-3NB2C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945676
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854434
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0542
GSE178714_5_v_4_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cochlear duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.371994
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.222938
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
4EGI-1_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0148804
Perturb_11256_KO_Nek7_SRP375473	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.22767
heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.120379
GSE213588_8_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
WASF1	Pathway Commons Protein-Protein Interactions	1.0	null
Elagolix sodium_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0105328
PMC10534007-Table_2.xlsx-S4_unique_down_MSC_V-745_elements_included_exclusively_in_VM-CUB1_MSC_down_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149359_3_v_0_asap2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
atrial heart septal defect	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.882701
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.1034
hsa-miR-4282	TargetScan Predicted Conserved microRNA Targets	1.0	0.31417
PMC8370976-41467_2021_24932_MOESM6_ESM.xlsx-Annotation-Supplementary_Data_4_GO_and_metascape_analysis_of_the_genes_downregulated_in_U87_cells_upon_ZNF768_knockdown_ZNF768	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8403-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.949118
GTEX-WHPG-0626-SM-3NMBD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841079
CTNND2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE178714_5_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU761	DepMap CRISPR Gene Dependency	1.0	2.17346
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.867238
MTF2	ChEA Transcription Factor Targets	1.0	null
hsa-miR-583	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
blastula	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.102537
GTEX-TMMY-0008-SM-4DXU3	GTEx Tissue Sample Gene Expression Profiles	1.0	2.27017
PMC6459557-pbio.3000201.s012.xlsx-Sheet1-FOXD1_FOXD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE240386,GSE242143_1_v_4_morc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NB1	DepMap CRISPR Gene Dependency	1.0	2.29653
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19598
lateral hypothalamic area, mammillary region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12256
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GSE129811_5_v_0_niacin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-V955-0004-SM-3NMDH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10489
RELA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5
GSE165636_0_v_4_tofacitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_downregulated_genes-Unnamed_6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.50691
endometrium_5a	HPA Tissue Sample Gene Expression Profiles	1.0	0.988309
GSE207582_4_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Endothelioma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.083
GSE125782_3_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE173873_8_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S341-0008-SM-4AD6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1109
GSE203267_0_v_1_alkbh5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.70487
SKN	DepMap CRISPR Gene Dependency	1.0	5.72282
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6907
ST486	CCLE Cell Line Gene CNV Profiles	-1.0	-2.06698
hmc1	HPA Cell Line Gene Expression Profiles	-1.0	-0.894171
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-RQ-A6JB-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_6609_KO_STK11|KEAP1_ERP124775	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
CAL-12T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZFX_KO_GDS2718_150_mouse_embryonic stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7825
cancer	GAD High Level Gene-Disease Associations	1.0	0.293278
GSE165704_0_v_1_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_13_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-N7MS-0008-SM-4E3JI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24276
GSE216273,GSE216292_14_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NFYB	ENCODE Transcription Factor Targets	1.0	null
GTEX-PWOO-0008-SM-48TDU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74832
GATA3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22953
Lung adenocarcinoma_LUAD_TCGA-38-4627-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE119498_0_v_7_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10794847-mmc2.xlsx-PBRM1_KD_down-Table_S1_Differentially_expressed_genes_with_PBRM1_knockdown_in_the_progenitor_state_Related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WQ-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE92457_7_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Breast Neoplasms	CTD Gene-Disease Associations	1.0	1.51708
H4K20me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Folic_Acid-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
RUNX1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
GSE164874_5_v_0_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
frontal pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.38692
medial amygdala, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56263
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4865-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE136894_1_v_0_psen1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NL3G-0008-SM-4E3JX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937985
superior colliculus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.29044
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5884-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11960529-mmc4.xlsx-Ventricular_ZNF711_KOoverCT-gene_ZNF711	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-3163	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
GSE169356_0_v_3_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Unnamed_12_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51015
GSE119498_0_v_5_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GATA3_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPL-0008-SM-4E3I9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19984
feather	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.77857
SSTR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02941
BL6534 (TRAF3IP1)	NURSA Protein Complexes	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51R-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Colorectal Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Perturb_1670_KO_Rigi_SRP119759	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.6943
TAF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8XE-0008-SM-4E3K4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02653
Lung squamous cell carcinoma_LUSC_TCGA-18-3409-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_3835_KD_RNPK_SRP342664	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
brain development	GO Biological Process Annotations 2025	1.0	null
NCIH2342	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63645
placenta_3a	HPA Tissue Sample Gene Expression Profiles	1.0	1.21486
Perturb_2087_KO_APTX_SRP174572	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE205163,GSE205164_3_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
Hypertension	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.545
GSE246195,GSE246305_2_v_0_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
superficial stratum of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46051
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE180200,GSE180201_2_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE239844_4_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HYAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4555
Perturb_13181_Mut_Cry2_SRP303502	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.68578
vestibular labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.283545
LU65	DepMap CRISPR Gene Dependency	1.0	2.57704
hsa-miR-3660	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Ventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75072
Perturb_6944_KO_Xirp2_SRP259323	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.73438
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02538
hepg2	HPA Cell Line Gene Expression Profiles	-1.0	-0.894171
HMC18	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3612
Perturb_13790_KO_Zeb2_SRP066910	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Intestine	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
glial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.139331
GSE133213_6_v_13_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE176008_0_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lonafarnib_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0206596