association	dataset	threshold value	standardized value
abducens nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.8492
SINHCAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77418
BRAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25229
SU-DHL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Transitional cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.682
HNRNPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.16852
NAPRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67408
liver	HPA Tissue Gene Expression Profiles	-1.0	-0.932793
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CHD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41985
NRDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15456
Mitotic cohesin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.738
PLA2G12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20742
LCN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03545
biological_process	GO Biological Process Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-8185-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SELENOK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71166
FEZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73834
endometrium_4b	HPA Tissue Sample Gene Expression Profiles	1.0	0.851483
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.835608
chr5_141195638_G_T_b38	GTEx eQTL 2025	1.0	1.04589
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9947
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.839544
Lung adenocarcinoma_LUAD_TCGA-50-5935-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial parabrachial nucleus,right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.854729
thorax	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064425
Integument	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.157
cation binding	GO Molecular Function Annotations 2015	1.0	null
GSE184087_4_v_5_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.66425
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3KJ-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3668	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GSE190316,GSE190324_6_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
SLC16A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04865
GTEX-P4PQ-0726-SM-3NMCR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966614
K029AX	DepMap CRISPR Gene Dependency	1.0	2.63605
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5550-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LAMA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12232
outer CP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.40458
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-GK-A6C7-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.849557
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-A7CX-01A-12R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_medulloblastoma_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
ZNF841	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87216
CD276	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89985
hnf4a_21852396_wao9_lof_human_gpl570_gds3926	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.081185
liver	GTEx Tissue Gene Expression Profiles	-1.0	-1.16612
DHX32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32388
Brain Lower Grade Glioma_LGG_TCGA-HW-A5KJ-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MKN1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QCQG-1926-SM-2S1PI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08735
endometrium	HPA Tissue Gene Expression Profiles	1.0	1.0342
GSE172016_2_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
GTEX-TSE9-3126-SM-4DXSY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953382
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A217-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
BARHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5029
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CAMSAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49378
CAS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.921407
lateral group of nuclei, right, ventral division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.38165
hippocampus (hippocampal formation)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13915
SIN3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59345
inner CP in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.54206
PCBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22196
orbital frontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.981541
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5788
RP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1202
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CTCF_mammary epithelial cell_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27141
TRIM26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29411
MSLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63673
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZN-0726-SM-4DXT5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47745
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3YL-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81Q-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-5874-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PKIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35144
COLO668	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40371
DYNC2I1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55305
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.75985
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.16927
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16058
FBXO48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55953
SETD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75208
G70101JE	GlyGen Glycosylated Proteins	1.0	null
KLK10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77914
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03446
Brain Lower Grade Glioma_LGG_TCGA-FG-7634-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34184
CTCF_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WY7C-2826-SM-3NB3Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05057
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.20166
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05836
GSE199538,GSE199539_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GP5D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.866478
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
MYBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79506
GTEX-P4PP-0008-SM-48TDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.960929
KCNE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07069
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.35387
globe disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.27153
GBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22331
GSE149760_0_v_1_elof1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF485	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86183
PCYOX1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83569
GTEX-U3ZG-0001-SM-47JYF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.950206
EDF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39992
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PRDM12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11937
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POU5F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93266
INTS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69022
CYB5R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42631
SW 480	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.88609
GTEX-PVOW-0011-R5A-SM-32PL7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17394
NARF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4741
EBNA1-20929547-CHIP-SEQ-RAJI-CELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.06493
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B5-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	68.0784
GTEX-U3ZH-0002-SM-3NMDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
AFAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80874
COLO679	DepMap CRISPR Gene Dependency	1.0	2.13502
ATP6V1F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56232
PRRX2	JASPAR Predicted Transcription Factor Targets	1.0	null
CRABP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06047
POMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39897
GSE235066_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE245270_2_v_0_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW1088	CCLE Cell Line Gene CNV Profiles	1.0	1.48222
GTEX-P44H-0011-R1A-SM-3NM8J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892996
HCC364	Achilles Cell Line Gene Essentiality Profiles	1.0	1.00682
GTEX-T5JW-0003-SM-3NMAD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01708
TCEAL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58548
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NTERA-2_CL_D1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
anterior group of nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.828346
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
CTCF_fibroblast of pedal digit skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Retinal rod	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.74
Lung squamous cell carcinoma_LUSC_TCGA-18-3406-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.865613
Sarcoma_SARC_TCGA-HB-A3YV-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
Lung adenocarcinoma_LUAD_TCGA-64-5815-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COV504	Achilles Cell Line Gene Essentiality Profiles	1.0	1.16385
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Fetal alcohol spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
Perturb_13379_OE_SFRP2_SRP115559	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.49357
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
GSE235066_4_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.19944
USP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48139
DU-4475	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OIZI-1126-SM-3NB1F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26801
PPP4R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99914
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943809
DLG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.33473
CDKN2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24986
SPG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49518
DOHH2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50177
GTEX-T6MN-0426-SM-32PMF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900651
GSE192870_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.925104
central medullary reticular group, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01382
GTEX-S4Q7-0003-SM-3NM8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7890-01A-12R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57349
Lung squamous cell carcinoma_LUSC_TCGA-56-A4BX-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01066
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCFL_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6778-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C16orf54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05009
ERG-21242973-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
DARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50813
GSE205687_1_v_0_mta1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.993231
IGFBP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01027
CTCF_WI38_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE178714_5_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NFE2L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44945
GTEX-XBED-2426-SM-4AT4O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06529
HSPA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66477
H3C3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47332
NIPAL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86076
UACC893	DepMap CRISPR Gene Dependency	1.0	4.3664
ADAMTS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25943
EPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99321
BOD1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65882
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
Lung adenocarcinoma_LUAD_TCGA-55-6969-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HSPA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71296
19658189-TableS3	GeneSigDB Published Gene Signatures	1.0	null
GSE206984_1_v_0_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RABEPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06907
MAEA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40509
RNF38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99297
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0627
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6228-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF556	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24734
nucleus subceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08632
GTEX-U3ZN-0002-SM-3NMDF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
FYN	Pathway Commons Protein-Protein Interactions	1.0	null
H4K20me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE214931_2_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FTC238	CCLE Cell Line Gene CNV Profiles	1.0	1.58219
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32407
RTCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01286
testis	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Acute Myeloid Leukemia_LAML_TCGA-AB-2839-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Wnt signaling pathway	PANTHER Pathways	1.0	null
DMS153	CCLE Cell Line Gene CNV Profiles	-1.0	-1.91127
SKOV3	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.48348
SDHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17371
DNASE1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3745
central medullary reticular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.983423
Lung adenocarcinoma_LUAD_TCGA-69-7973-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-T2-A6X0-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.67707
GSE186471_1_v_2_carnosol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.32346
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50573
Lung squamous cell carcinoma_LUSC_TCGA-18-3408-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF140	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.7011
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15733
TMEM59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12811
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4977-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner CP in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.911635
IL17RB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62731
APBB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42358
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.50098
HTRA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10193
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942769
NR5A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27306
CHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11862
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.596
ZNF549	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22694
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
anterograde trans-synaptic signaling	GO Biological Process Annotations 2023	1.0	null
CTCF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23693
NCCIT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-W5X1-2326-SM-3GIL6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877895
SLIK (SAGA-like) complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.578
FREY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22373
SW837	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5B-Up_H3K4me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45U-01A-12R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.8645
pou5f1_20526341_human_embryonic_stem_cells_hesc_lof_human_gpl6947_gse21135	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.152773
PABPC1L2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88186
ADIPOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82452
rpmi8226	HPA Cell Line Gene Expression Profiles	-1.0	-1.28527
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.915289
Brain - Putamen (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.19521
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.6647
MGST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5133
Lung squamous cell carcinoma_LUSC_TCGA-37-5819-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Medial entorhinal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.137
GSE214931_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
orbital frontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.4313
GSE210101,GSE210114_8_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.914683
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A7CZ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FUZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14123
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33327
ECHDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43957
MZ2-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.979166
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.38934
pituitary	GTEx Tissue Gene Expression Profiles	1.0	1.15621
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.8143
FKBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46059
SPTBN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08884
Kidney Chromophobe_KICH_TCGA-KM-8443-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF394	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49514
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6848-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MSX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8096
POU3F2-20337985-501MEL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SETD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32074
hsa-miR-494	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
LEMD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94175
MESP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01087
GTEX-WFON-0526-SM-4LVLY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30514
Lung adenocarcinoma_LUAD_TCGA-44-5644-01A-21R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRAPPC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12427
SLC46A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59968
COLO320	DepMap CRISPR Gene Dependency	1.0	4.73752
OPM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.431
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12717
hsa-miR-3662	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
JHOS4	CCLE Cell Line Gene CNV Profiles	1.0	1.87873
Eye	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.242
FAM83G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12199
SLAIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58844
GTEX-TKQ2-0926-SM-4DXU5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938679
Lung adenocarcinoma_LUAD_TCGA-64-5775-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SAMD4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23147
GSE175787_5_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_6_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RAD21_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOHLH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32191
GTEX-POMQ-0008-SM-48TE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.89162
Lung adenocarcinoma_LUAD_TCGA-50-6592-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
INSIG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9587
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
GSE168401_1_v_3_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EFO21	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.10881
MCF 10A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.69111
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054129
VZ in subgenual cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.34555
ARL4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21367
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.43919
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-P4QS-0426-SM-3NMCQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64645
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31394
ERF::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1164
PRM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55882
hsa-miR-4742-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
RHOBTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72479
SIG-M5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE175787_8_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HUP-T4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Small intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.157
GTEX-SSA3-0002-SM-3P61R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
Lung squamous cell carcinoma_LUSC_TCGA-22-4593-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
supramarginal gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.980355
CKAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45398
RPS26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66306
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.916058
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2559
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
STARD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59099
KIF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09943
CAL-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FBRS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86966
ZNF562	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44809
19168792-TableS3	GeneSigDB Published Gene Signatures	1.0	null
UWB1.289 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.997
GSE214931_3_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
C2CD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10494
TSSK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96364
CTCF_GM12870_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS 695T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4W0-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PVOW-2726-SM-48TCA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836591
PEA15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67979
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.70929
hsa-miR-532-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Cervix - Ectocervix	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.06535
LRRC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23599
MO-T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_keratinocyte_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYL12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36784
GTEX-N7MT-0011-R5a-SM-2I3G6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840557
MAP2K3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18392
ATP2A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5378
GTEX-T6MN-0326-SM-32PMK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958396
PLAA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84554
ORAI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14238
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
GTEX-S4Z8-0726-SM-4GICB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20235
ANXA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08489
Skin - Sun Exposed (Lower leg)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.701733
Colon - Transverse	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.15192
IER5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0834
WWP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55354
BRCA1_DEPLETION_GDS3791_502_human_Hela cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CTCF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0208
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23213
CORL88	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43445
RAD21_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PALM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15885
ALKBH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00435
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02951
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell-cell adhesion	GO Biological Process Annotations 2015	1.0	null
Cadherin, N-terminal	InterPro Predicted Protein Domain Annotations	1.0	null
SK-MM-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QVJO-0526-SM-447CE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02026
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01011
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2591
GSE135400_1_v_0_kdm1b_human	RummaGEO Gene Perturbation Signatures	1.0	null
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3I0-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine cervix	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.157
SLC30A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68092
dexamethasone_homo sapiens_gpl6244_gse20963	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.079783
AKIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7062
Prostate adenocarcinoma_PRAD_TCGA-HC-7213-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLEKHH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11243
internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.090078
KIAA0930	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83791
MZ7-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SFMBT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1161
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
MZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.873517
CHST7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98877
NCI-H28	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-562	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CYREN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89022
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.869697
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A71A-01A-22R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
frontal pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.2016
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.25168
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.87256
GTEX-SNOS-0003-SM-3NMAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888969
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
IGR39	CCLE Cell Line Gene CNV Profiles	1.0	1.39854
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06691
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
MTFP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46966
Lung squamous cell carcinoma_LUSC_TCGA-34-2596-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
TGFB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42271
ZBED1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5949
ZNF486	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05111
MCFD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82258
TSPAN14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40616
pcgf2_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.156104
DYNLT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56613
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28329
NKX2-5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77096
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CBX3_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
GTEX-NPJ7-0011-R11A-SM-2I3E8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2582
JHH-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0035
CTCF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3910	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
ACCMESO1	CCLE Cell Line Gene CNV Profiles	1.0	1.74865
GTEX-V955-0004-SM-3NMDH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.950185
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5362
PMC10315050-12920_2023_1588_MOESM2_ESM.pdf-27-THAP9_THAP9	Rummagene Transcription Factor Associations 2026	1.0	null
TMUB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76253
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
SRSF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21403
PODXL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94225
GSE161864,GSE161866_0_v_2_ror2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HS 38.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07163
SCAMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27164
GSE151090_5_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6145927-41467_2018_5729_MOESM6_ESM.xlsx-TF_Activity_Genesets-SNAIL_UP_SNAI1	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_MEL cell line_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.93467
KMH-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CAL51	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.11016
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3129-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Lung squamous cell carcinoma_LUSC_TCGA-56-8628-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C2orf69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97829
SLITRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73152
Lung squamous cell carcinoma_LUSC_TCGA-77-7140-01A-41R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
M059J	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
ELAVL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97737
RAD21-21589869-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.862024
spleen	HPA Tissue Protein Expression Profiles	-1.0	-1.30659
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11424
SNU349	CCLE Cell Line Gene CNV Profiles	1.0	2.74063
SPECC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5405
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
substantia nigra, pars compacta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.31074
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.911777
refractive error	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.00203
GTEX-UPK5-1426-SM-4JBHH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.8737
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BET1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62185
SKN	DepMap CRISPR Gene Dependency	1.0	3.89323
PLB985	Achilles Cell Line Gene Essentiality Profiles	1.0	1.24716
CTCF_fibroblast of pulmonary artery_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6268
SWI5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48808
GTEX-R55G-0426-SM-48FDH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23952
SYT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9831
WFDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54207
ARX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24474
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.15854
PFDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29278
sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.24996
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
Lung adenocarcinoma_LUAD_TCGA-86-8673-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE133087_5_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ADAM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70488
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chr5_141189780_G_A_b38	GTEx eQTL 2025	1.0	1.50117
ChIP_CTCF_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
LIN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64045
SGSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57488
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41066
TE-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-V955-0926-SM-4JBJ8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04655
HT-1197	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1734	COSMIC Cell Line Gene Mutation Profiles	1.0	null
VZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26422
melan-a cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.52
Rectum adenocarcinoma_READ_TCGA-EI-6509-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GA-10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AFTPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99976
CTCF_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRKX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28497
CNTRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25019
GTEX-V1D1-0326-SM-4JBIY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829713
BRAF_druginhibition_175_GSE42872	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.62098
JMJD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20828
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.922017
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.7745
Brain Lower Grade Glioma_LGG_TCGA-CS-5390-01A-02R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZSCAN25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20279
GSE213228_2_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ATOH7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.342
CTCF-33576154-HUMAN-HILARLN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0605
HEXA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76108
HCC202	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.06993
CRLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8717
KDM4C_natural variation_GSE41040_588_human_fibroblasts fron neonatal foreskin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-POMQ-1426-SM-3P61D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30243
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.868171
OARD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53019
NANOS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56682
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03848
KALS1	CCLE Cell Line Gene Expression Profiles	1.0	1.37175
NCI-H508	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH716	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.40048
CRACR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02303
hsa-miR-548h	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GSE162892_4_v_2_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03583
LIN28A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60968
RIPPLY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62732
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22599
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
MSTO-211H	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RAD21_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral hemisphere of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05861
u698	HPA Cell Line Gene Expression Profiles	-1.0	-1.28527
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.985739
Brain Lower Grade Glioma_LGG_TCGA-HT-A74L-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VUSG-2826-SM-4KKZM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02339
SUPT6H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68747
SVBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72303
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15573
ZCCHC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16834
Brain Lower Grade Glioma_LGG_TCGA-HT-7469-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05927
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06813
Lung adenocarcinoma_LUAD_TCGA-55-1592-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8620-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
granular layer of caudal dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.7542
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.10971
CNNM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58299
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.904709
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
synapse organization	GO Biological Process Annotations 2015	1.0	null
AN3 CA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17461
TMEM86A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31676
TDRD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57512
GTEX-T2IS-3126-SM-32QPK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53844
GSE138863_2_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1469
PMC8292420-41598_2021_94064_MOESM5_ESM.xlsx-Sheet1-Supplementary_Table_S4_AA_ESCC_SNVs_and_short_InDels_that_were_previously_identified_and_listed_in_COSMIC_database_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
496100303_HIP_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.23767
CTCF_fibroblast of foreskin _hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
RAD21_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CERF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.755
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.994344
Rectum adenocarcinoma_READ_TCGA-G5-6572-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LAMA-84	COSMIC Cell Line Gene Mutation Profiles	1.0	null
smoothmuscle_8a	HPA Tissue Sample Gene Expression Profiles	1.0	0.988093
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.895516
COX7A2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90685
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.3555
GSE196343_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-4692	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GSE102132_2_v_1_irf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-R53T-1826-SM-3GIJX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830934
Occipital lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.429
GSE210101,GSE210114_7_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FBXO21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62149
ATPSCKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91256
SMIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67912
GSE132694,GSE132717_0_v_2_meis1_human	RummaGEO Gene Perturbation Signatures	1.0	null
WDR90	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43827
SW 837	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.62405
GSE77108_8_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-1273e	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
HAL-01	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XV7Q-1526-SM-4BRWB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06705
PMC11979751-table_s1_trajectoryderivation_elad055.xlsx-Cluster_DE_Genes_Summary-Cluster_2_AP2_Up_GTF3A	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1569	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.774782
GSE231524,GSE231526_0_v_1_dusp6_human	RummaGEO Gene Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.924054
TOPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45249
ACAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18767
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.835608
GTEX-VJYA-1726-SM-3NMDQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848254
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QI-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZFTRAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89925
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MK-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE229070,GSE229071_0_v_2_sotorasib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S4UY-1426-SM-4AD6Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08333
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
Mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.157
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01066
GTEX-S32W-0426-SM-4AD6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4916
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33327
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5435-01A-01R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1105	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50312
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X5EB-0004-SM-46MWA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
CLEC11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35141
NPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51951
Lung adenocarcinoma_LUAD_TCGA-50-8459-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6683136-41598_2019_47363_MOESM2_ESM.xlsx-GENE_SET-Positive_correlation_of_ZEB1-AS1_and_other_genes_ZEB1	Rummagene Transcription Factor Associations 2026	1.0	null
CBX3	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5494-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33476
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.864788
Prostate adenocarcinoma_PRAD_TCGA-G9-6364-01A-21R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WDR11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84958
RCC-AB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ATP13A2	Pathway Commons Protein-Protein Interactions	1.0	null
RGS14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97119
synapse assembly	GO Biological Process Annotations 2023	1.0	null
ZNF318	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63888
RCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44917
KIRREL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95846
MAFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4742
POLR2E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32761
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
496100547_HIP_no dementia_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.19023
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P78B-1326-SM-3P611	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874596
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Amylin receptor complex 2	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.409
hippocampus (hippocampal formation)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03206
CTCF_fibroblast of lung_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ERBB2	Pathway Commons Protein-Protein Interactions	1.0	null
SMURF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90719
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.68083
GSE175787_5_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Vitelline envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.742
cell-cell adhesion via plasma-membrane adhesion molecules	GO Biological Process Annotations 2025	1.0	null
GTEX-U4B1-0008-SM-4DXUW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.937568
hsa-miR-186	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
HUH7	DepMap CRISPR Gene Dependency	1.0	3.44646
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	99.3935
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61054
GTEX-R55E-0006-SM-2TC5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
QGP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.847675
RNF168	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59497
HLF	Achilles Cell Line Gene Essentiality Profiles	1.0	1.46007
SP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08071
chemical synaptic transmission	GO Biological Process Annotations 2023	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28166
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.916058
Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YN-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3246
CLTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61321
GTEX-W5X1-0006-SM-3GIJZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
CTCF_astrocyte of the spinal cord_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBXN2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03898
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TMBIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95519
GSE195559_6_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Colorectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.157
CHCHD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55555
PPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36743
ALG12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87004
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.973865
AGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20013
PSAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70945
rostral division of OFCi (area 11)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.58086
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
PFKL_OE_GDS4410_202_human_biceps	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.157
CTCF_choroid plexus epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7293
RAD21_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYCN-21190229-SHEP-21N-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66308
GSE178714_1_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC2263127-pone.0001816.s001.xls-E2F3_down_Bild-Symbol_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-HB-A5W3-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TUBB4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32027
hsa-miR-4269	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
PITX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81416
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PRPSAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0572
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.3069
Prostate adenocarcinoma_PRAD_TCGA-KK-A59Y-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2806-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mda-mb-231 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.459532
RAD21_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHPG-2326-SM-3NMBP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847195
GTEX-X261-3226-SM-3NMC3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966879
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.858968
MND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63819
breast cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.080906
DPY-21335234-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K27me3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
16288011-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
CL-34	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_13371_OE_TRF2_SRP290161	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.54414
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.3095
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.82757
hsa-miR-4307	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
CTSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.50148
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZS-06A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FLVCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8669
KCNE5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27608
RBBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21282
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.058
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.85656
ZNF565	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59642
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2403
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.957227
JUN_01_172	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.73608
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6827-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NBEAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3675
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SU8686	Achilles Cell Line Gene Essentiality Profiles	1.0	1.29538
Epididymis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.157
hsa-miR-635	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
lateral group of nuclei, left, ventral division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18467
parathyroid gland	HPA Tissue Protein Expression Profiles	-1.0	-1.30659
PIKFYVE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31473
SU-DHL-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
temozolomide_homo sapiens_gpl10558_gse43452	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE175787_5_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.867283
GTEX-R55E-2726-SM-48FCX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06549
PPP2R5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32861
CHST12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60992
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1768
METTL22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5937
ZNF337	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98863
CACNA2D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36247
PMC6167382-41467_2018_6258_MOESM4_ESM.xlsx-TEAD-associated_GSC-Specific_UP-Nearest_Ensembl_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
LC1SQ	DepMap CRISPR Gene Dependency	1.0	7.49681
FER	Pathway Commons Protein-Protein Interactions	1.0	null
NIBAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21541
SYTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07356
hsa-miR-1248	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
NUDT14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33686
rnf2_21051595_92dot1_lof_human_gpl10558_gse24896	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.561546
GSE175787_8_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
amygdaloid complex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.9383
RAD21	ChEA Transcription Factor Targets	1.0	null
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91477
IMR-32 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.708
Perturb_11550_KD_HNRNPC_SRP366058	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE225901_2_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE245270_2_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-P4PP-2026-SM-3P61N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69773
GTEX-XV7Q-1426-SM-4BRWA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988813
GTEX-XPVG-0926-SM-4B651	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850197
GTEX-X88G-0004-SM-47JZ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926016
Retinitis pigmentosa 11	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.195
GTEX-RN64-0526-SM-2TC5P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04118
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.75483
NCI-H727	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
GTEX-RWS6-1326-SM-47JXB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24309
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GO-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LU-134-A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RAD21_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS 578T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04019
hsa-miR-664	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
stratum pyramidale of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02388
Brain Lower Grade Glioma_LGG_TCGA-DB-A64P-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1272	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
granular layer of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1145
NCIH146	CCLE Cell Line Gene Expression Profiles	1.0	1.51784
Prostate adenocarcinoma_PRAD_TCGA-HC-7821-01A-12R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NSMCE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33054
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.78791
Lung squamous cell carcinoma_LUSC_TCGA-77-7335-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTF2A1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25113
GTEX-Q2AG-0526-SM-2S1PW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911044
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.912897
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.868819
GTEX-S32W-0526-SM-4AD6F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23338
GTEX-QDT8-1026-SM-43V6X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47748
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Q-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATXN1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92314
CA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32543
A-Netherlands-602-2009(H1N1)_48Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.3542
CEP290	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96754
MED13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79345
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STT3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77509
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02128
PMC7021759-41467_2020_14682_MOESM10_ESM.xlsx-downregulated_genes-Table_S7_Dowregulated_genes_in_SKNMM_and_U2OS_cells_with_MYCN_induction_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
USP19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85239
MIDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76037
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5469-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06452
PMC10864182-41588_2023_1596_MOESM4_ESM.xlsx-ST12_Significant_Genes_combine-Supplementary_Table_12_Genes_prioritisation_combining_FUMA_MAGMA_Hi-C_MAGMA_and_TWAS_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
ANKLE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04397
143B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.08303
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.676
YIPF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56506
20460173-ImmPortComprehensiveListofImmune-RelatedGenes	GeneSigDB Published Gene Signatures	1.0	null
substantia nigra, pars reticulata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14223
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QW-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H9	COSMIC Cell Line Gene Mutation Profiles	1.0	null
STEEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31272
GSE192870_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-V1D1-2626-SM-4JBJH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06098
TBCCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72068
GSE262134_0_v_1_dnajc12_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE120216_3_v_0_cbfb_human	RummaGEO Gene Perturbation Signatures	1.0	null
COPG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69726
GTEX-VJYA-0001-SM-3NMDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00342
GTEX-SUCS-0002-SM-3NMAJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01534
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
GSE77108_4_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_fibroblast of lung_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4C7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81879
Adrenocortical carcinoma_ACC_TCGA-OR-A5JI-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
caudal division of IPC (area 39)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.69622
PSMD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66364
RARA_KD_GDS4065_42_human_MCF-7	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
GTEX-RN64-0726-SM-48FCV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2995
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.91168
KIF5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78909
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
CTCF_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-3026-SM-3NMA2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5193
184A1N4	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.12133
SHMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.235
DOK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.866478
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RAD21_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF750	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91298
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.68083
SUZ12	ChEA Transcription Factor Targets	1.0	null
Artery - Coronary	GTEx Tissue Gene Expression Profiles 2023	1.0	1.46695
GSE216043_3_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3644
GTEX-PW2O-0426-SM-48TCC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77282
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7369-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
15361855-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.982843
L363	Achilles Cell Line Gene Essentiality Profiles	1.0	1.25066
WSU-DLCL2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MIEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6612
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064627
LOVO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.69111
GTEX-XMD1-2826-SM-4AT5F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23125
CLASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81809
ANGEL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56338
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
HCC1395	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.05391
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
GTEX-R55E-0008-SM-48FCG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858429
GTEX-UPIC-0002-SM-3NMDC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
HCC38	CCLE Cell Line Gene Expression Profiles	1.0	2.34738
HDAC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77886
TFPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30625
CTCF_HCT116_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ANO8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79356
H3K9me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7014-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE79572_0_v_1_pax8_human	RummaGEO Gene Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-WK-A8XQ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A9FL-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
NCIH1581	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59052
OV-90	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
SK-N-FI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PGM2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47571
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.6789
GUSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42976
CTCF_GM13977_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.58244
hsa-miR-545	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
KRT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99671
RAD21_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sense organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.242
Condensin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.965
hsa-miR-548w	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GSE193258,GSE193259_9_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6932815-ppat.1007634.s015.xlsx-ST5_DGE_ELF1-R8AvIFN48-mock_lfc-ensembl_gene_id_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SHPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59092
MRPL37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57324
GTEX-X585-0011-R10A-SM-46MUY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99313
EPHX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38867
C2CD4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27302
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4894-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UPIC-0926-SM-4IHLV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.924674
FUOM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16474
synapse assembly	GO Biological Process Annotations 2015	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8437-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-SU-A7E7-01A-22R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04761
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5832-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EPHA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17454
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
ISYNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53232
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TUBA1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40287
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96804
CTCF_GM12864_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-548y	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GSE205729,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
supraoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.892338
Buccal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.753
SMC loading complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.092
FAM170A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97593
C15orf39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00018
anterior group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.35099
hsa-miR-577	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
CTCF_epithelial cell of proximal tubule_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.7796
GTEX-XQ3S-0126-SM-4BOO9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08757
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.496
PLC/PRF/5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.930924
GSE247084,GSE247087_0_v_1_cdyl_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
REH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE242199_9_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J9-A8CL-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
motor nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.68261
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5183-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of villous mesenchyme_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CUX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13647
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.949361
GTEX-U3ZN-0008-SM-4DXTL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.834944
EEF2K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69715
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A0S7-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MMS22L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25164
CDYL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05073
Rectum adenocarcinoma_READ_TCGA-F5-6813-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE233679_5_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MU-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE139455_4_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1422
Thyroid	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.53285
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02988
GTEX-OHPK-2026-SM-3MJH7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34024
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
OPM-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CD2AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59837
Lung squamous cell carcinoma_LUSC_TCGA-33-4583-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1155
SLC5A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38869
ABITRAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36638
primary motor cortex (area M1, area 4)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12879
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dhori Virus_24Hour_20090954_GSE17400	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.69373
RCC-JF	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cell adhesion	GO Biological Process Annotations 2015	1.0	null
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.83235
C170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.854419
POU5F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28676
DEOC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.12335
TPM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25222
GSE178714_6_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RAD21_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3686	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
ovary	HPA Tissue Protein Expression Profiles	-1.0	-1.30659
GSE139455_2_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FV-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-548n	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
PAOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16438
GSE189859,GSE189861_3_v_2_idh1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
JUND	ENCODE Transcription Factor Targets	1.0	null
FLOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29663
WM-266-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.889089
GRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41109
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.901372
HOP-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.28169
GSE196962_2_v_6_parg_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100521_HIP_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.18734
RT4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.51085
HCC1395	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.34122
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3M9-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039683
496100576_HIP_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.06594
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2BC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10194
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-T2YK-0008-SM-4DM6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
Sarcoma_SARC_TCGA-SI-AA8C-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC25A29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24797
motor nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.34496
GSE245270_2_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
ACD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7402
GSE244710_1_v_2_srsf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SK-N-AS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.824
hippocampus (hippocampal formation)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09405
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26253
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A410-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
prostate gland cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.317315
GTEX-REY6-1126-SM-48FDU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02383
GTEX-U8XE-1026-SM-4E3HM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43652
GSE115542_5_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ctf18 RFC-like complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.721
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.914839
GSE161864,GSE161866_4_v_3_ror2_human	RummaGEO Gene Perturbation Signatures	1.0	null
ATF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30312
GSE160442,GSE160444_1_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
TFEB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49438
GATA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05497
PMC3526356-supp_jem.20121387_JEM_20121387_sm.pdf-36-PAX6_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XMK1-2526-SM-4B666	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902309
GSE143782_3_v_4_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
RAD21-21589869-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
primary auditory cortex (core)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.67315
breast cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.085921
CTCF_GM12865_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GDAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66327
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4635	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
SW48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KDM4C_natural variation_GSE41040_589_human_fibroblasts fron neonatal foreskin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NR0B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32387
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
C3orf62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79613
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.901898
EARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00867
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Spondylocostal dysostosis 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.331
hsa-miR-4803	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
KIAA0753	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38255
Lung adenocarcinoma_LUAD_TCGA-78-8655-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-362-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
RAD21_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-70-6723-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A82F-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
GSE228106_3_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE168401_1_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
Lung squamous cell carcinoma_LUSC_TCGA-43-A474-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CORL311	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37869
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YV-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE130401_4_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4329
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06342
REP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56892
CACFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78009
LANCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79341
GSE218060_7_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
A2058	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.55831
SEPTIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2557
RWDD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45785
HNRNPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41982
primary motor cortex (area M1, area 4)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.960907
CD37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77802
Brain Lower Grade Glioma_LGG_TCGA-DB-A64R-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE186112_1_v_0_med23_human	RummaGEO Gene Perturbation Signatures	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.339
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03019
WEE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31799
posterior cortical nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01083
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.848047
GTEX-TKQ1-0008-SM-4DXSO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.84195
TEAD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19585
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866335
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19206
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.37064
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.234
GTEX-XBED-0726-SM-4GIAR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915595
CTCF_fibroblast of foreskin _hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TOV-112D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
PMC8025515-12859_2021_4105_MOESM12_ESM.xlsx-PW1-gene_stable_id_PEG3	Rummagene Transcription Factor Associations 2026	1.0	null
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6551
BARX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39229
GTEX-WL46-3026-SM-3LK7Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34213
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00414
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
Adrenocortical carcinoma_ACC_TCGA-OR-A5K5-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE239688_4_v_3_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.87472
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
TAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.795
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.31954
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.884272
GSE190316,GSE190324_1_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCFL_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80P-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FGD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43864
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824493
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5877-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.3434
ADCYAP1R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16251
Synapsis initiation complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.83
AP2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00594
CTNND1	Pathway Commons Protein-Protein Interactions	1.0	null
CORL23	DepMap CRISPR Gene Dependency	1.0	2.18589
KNS60	Achilles Cell Line Gene Essentiality Profiles	1.0	1.58011
U-698-M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7203
H3K9me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RIPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10337
CAPAN-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.732
769-P	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNU410	CCLE Cell Line Gene CNV Profiles	1.0	2.31765
MAZ	ENCODE Transcription Factor Targets	1.0	null
YPEL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92099
FRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88601
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6836-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.900081
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.5284
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.835802
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HI-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.8665
stratum pyramidale of caudal CA3	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.42152
SUDHL8	DepMap CRISPR Gene Dependency	1.0	6.69807
TCC-SUP cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.258
Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KR-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRRC2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81937
TSEN15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22483
GSE171352_2_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain - Frontal Cortex (BA9)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.14326
LARP4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69795
GTEX-T5JC-0008-SM-4DM6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.966598
GSE196835_0_v_1_ddx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5769-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6516
ARMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66715
cell-cell adhesion via plasma-membrane adhesion molecules	GO Biological Process Annotations 2023	1.0	null
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
GARIN5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33132
Neuroblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.147
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72402
brain	HPA Tissue Gene Expression Profiles	1.0	1.4696
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3167
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3945
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-2.06114
SW837	CCLE Cell Line Gene CNV Profiles	1.0	1.50076
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MRK-NU-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KK-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MON1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24841
Cadherin conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
CCDC90B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77832
PMC3921136-CIN-13-2014-021-s001.pdf-146-PAX3_PAX3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X4XX-0011-R10B-SM-46MWO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961369
GSE210101,GSE210114_1_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE129241_4_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-UJHI-0226-SM-4IHJL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07504
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.864639
GTEX-U3ZN-0426-SM-4DXSH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03993
eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056481
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1283
PMC7857731-elife-63093-supp5.xlsx-ECMdegsTCGAMITFlowvs_high-Differentially_expressed_ECM_genes_in_MITFlow_vs_MITF_high_tumours-SKCM_TCGA_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.862024
GTEX-UPK5-0003-SM-3NMDI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.912703
GSE235550_1_v_0_hspa9_human	RummaGEO Gene Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.27342
PTAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5048
RPS6KB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21915
RTL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49487
ARL8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53148
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
TMEM102	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96744
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.91256
Brain Lower Grade Glioma_LGG_TCGA-DH-A7UR-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF614	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23718
ANAPC15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96688
GSE158743_1_v_2_nfkbia_human	RummaGEO Gene Perturbation Signatures	1.0	null
TDG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49276
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CTCF_SK-N-SH_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ESET-19884257-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
b9	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.747
SMC3	ENCODE Transcription Factor Targets	1.0	null
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
Lung squamous cell carcinoma_LUSC_TCGA-56-5898-01A-11R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PDIA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2039
CSNK2A2	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_6635_KO_SATB1_ERP024525	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-17.3757
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EH-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5590-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069772
GTEX-OXRN-2626-SM-48TBX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73388
hsa-miR-548a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
PSAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25865
IRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32567
ARPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08953
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
HCC2998	DepMap CRISPR Gene Dependency	1.0	2.07737
C1orf50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07171
NB13	DepMap CRISPR Gene Dependency	1.0	2.47532
FLI1-21867929-CD8-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-33-4533-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MECOM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28401
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3457
LBHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06122
GTEX-WFG8-0001-SM-4LVN8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
cell junction assembly	GO Biological Process Annotations 2023	1.0	null
hsa-miR-4482	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GTEX-S32W-2426-SM-2XCAT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845973
hsa-miR-3163	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.919268
DB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36505
retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.222938
GSE211262,GSE211263_3_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CDC42BPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81017
LRP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55914
GSE193402_0_v_3_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CCM2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74786
ZMYND11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36324
DIS3L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21126
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SMC3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.3113
CDCA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38089
Amylin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.12
Acute Myeloid Leukemia_LAML_TCGA-AB-2939-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210870_0_v_2_snai1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAJI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NAGK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52559
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.52198
outer CP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.883442
CP in rostral hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10791
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
KMS12BM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56017
GSE216273,GSE216292_0_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BCL9L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66214
496100320_PCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10039
GJC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3878
lingual gyrus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.20788
NCI-H747	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H460	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.13305
HS 695T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.47137
Brain - Amygdala	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.00474
GSE181461_1_v_4_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_HCT116_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6683136-41598_2019_47363_MOESM4_ESM.xlsx-GENE_SET-Positive_correlation_of_ZEB1_and_other_genes_ZEB1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE230263,GSE230265_5_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09989
PCDHB15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71108
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052099
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09036
A172	CCLE Cell Line Gene Expression Profiles	1.0	1.59363
paclitaxel_homo sapiens_gpl570_gse39042	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-N7MT-1426-SM-3LK5M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30255
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.38301
PMC8684775-CTM2-11-e640-s002.xlsx-Sheet1-Table_S3_MAF_file_of_the_CCS_samples_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM12870_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC3906982-1471-2164-14-830-S1.xlsx-Sheet1-Table_S1_HOXC9-responsive_genes_HOXC9	Rummagene Transcription Factor Associations 2026	1.0	null
MAPRE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.38456
CTCF-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-W5X1-0001-SM-3P61V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-S7PM-0426-SM-3NM91	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953787
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
496100502_TCx_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.50251
DBT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73106
RERF-LC-KJ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF484	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49019
GSE227698_5_v_4_g0s2_human	RummaGEO Gene Perturbation Signatures	1.0	null
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.5808
OVTOKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A7IP-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE216273,GSE216292_14_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_GM12875_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ion binding	GO Molecular Function Annotations 2015	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5888-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-590-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.14232
orbital frontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.13101
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2556
KBTBD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94541
AN3-CA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-VJWN-0426-SM-3GIJI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.929964
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4973-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE130401_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TBC1D17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44925
brain_3c	HPA Tissue Sample Gene Expression Profiles	1.0	0.967798
GSE210101,GSE210114_8_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE139455_0_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.076844
HCC1171	CCLE Cell Line Gene CNV Profiles	1.0	1.73745
GTEX-WH7G-0002-SM-4LVN9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
GSE220806_0_v_3_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.9815
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NOP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01264
TUHR14TKB	CCLE Cell Line Gene CNV Profiles	1.0	2.04152
CSNK1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46321
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.32483
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.890517
GSE178714_5_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
Adrenocortical carcinoma_ACC_TCGA-OR-A5JG-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QV31-0326-SM-447BM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28045
SP in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.852048
CEBPA-26348894-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE139016_3_v_2_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8066
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1836	CCLE Cell Line Gene Expression Profiles	1.0	1.48333
dorsolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.07123
GTEX-XLM4-3126-SM-4AT6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08668
Buccal epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.269
Testis	GTEx Tissue Gene Expression Profiles 2023	1.0	1.52756
Kidney Chromophobe_KICH_TCGA-KL-8344-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AMIGO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45537
ZNF143	ENCODE Transcription Factor Targets	1.0	null
GSE229973_3_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.68742
ZNF227	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21118
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
ventral tegmental area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.845407
Lung squamous cell carcinoma_LUSC_TCGA-85-7696-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KP-N-YN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-T6MN-2726-SM-4DM77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26399
GSE138863_3_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.239
GTEX-X4XY-0526-SM-46MW1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995487
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05045
IFI16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79859
hsa-miR-4514	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GSE216540_1_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZCCHC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85697
GSE197850_4_v_2_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IPO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66778
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.65759
PRMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12756
GTEX-WYJK-0005-SM-3NMA1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.998254
PMC7933708-mmc2.xlsx-DNMT-target_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OHPL-3026-SM-3MJGS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75462
GTEX-VUSG-0003-SM-3NMDK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
ASPC1	DepMap CRISPR Gene Dependency	1.0	7.44719
GSE143406_1_v_0_carfilzomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_Symbol_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
LN235	DepMap CRISPR Gene Dependency	1.0	2.71573
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6618
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.423
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06606
GTEX-WFG7-2326-SM-3GIKV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861408
ETS1	ENCODE Transcription Factor Targets	1.0	null
PYCARD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73455
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6105
H3K9me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TIMM50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50593
RIOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4741
HCC70	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Olfactory receptor neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.031
GMCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18852
GSE162892_3_v_2_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SKNFI	CCLE Cell Line Gene Expression Profiles	1.0	1.47322
OVCAR8	Achilles Cell Line Gene Essentiality Profiles	1.0	1.57739
hypoglossal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.312
GTEX-WCDI-0002-SM-3P61U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.999116
C11orf98	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.43586
primary motor cortex (area M1, area 4)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.860589
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
GSE162892_3_v_2_sox9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XE-01A-12R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0251
HLA-B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5514
PCNX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5468
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	GO Biological Process Annotations 2025	1.0	null
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
ACOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06413
GTEX-QVJO-0011-R10A-SM-2S1QJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09458
CTCF_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RM-A68T-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TDOTT	DepMap CRISPR Gene Dependency	1.0	4.71823
KANK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07627
Lung squamous cell carcinoma_LUSC_TCGA-90-A4ED-01A-31R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0832
nervous system development	GO Biological Process Annotations 2025	1.0	null
GSE139455_7_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BIRC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.69657
ZER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41512
Lung squamous cell carcinoma_LUSC_TCGA-85-8479-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44R-06A-41R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-X6-A8C7-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TML8-1426-SM-4DXUT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891712
NECTIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17569
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Transverse filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.534
GSE210870_0_v_1_snai1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7223-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19626
TTC38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46131
ZNF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33804
hsa-miR-539	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
CTCF_GM12866_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Heart - Left Ventricle	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.11729
Medial habenular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.707
EJM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
anterograde trans-synaptic signaling	GO Biological Process Annotations 2025	1.0	null
GTEX-WEY5-0001-SM-3P61Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-5899-01A-11R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rostral putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05889
CAMA1	CCLE Cell Line Gene CNV Profiles	1.0	1.72543
Sarcoma_SARC_TCGA-DX-A2IZ-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9049
G120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.89274
TMEM209	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1705
GSE178714_5_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T6MN-0011-R11A-SM-32QOX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962404
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4139
H3K27me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-MJ-A68H-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.829754
THEM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13044
H3K9me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19D-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-UZ-A9PJ-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAB8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82526
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.67966
GTEX-O5YT-0426-SM-3MJHD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78642
vitamin c_homo sapiens_gpl570_gse11919	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CCDC103	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5438
PMC9424213-41467_2022_32537_MOESM5_ESM.xlsx-HeLa_IER3-AS1sh_DEGs-DEGs_in_HeLa_IER3-AS1sh_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
SEPTIN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68569
JURKAT, CLONE E6-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.925119
FOXA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15058
KLK13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60687
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6294
Bb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.602
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09989
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3373-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCOR1	ChEA Transcription Factor Targets	1.0	null
MZ in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.978274
MYC_KD_GSE22139_685_human_medulloblastoma	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LTBR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51711
homophilic cell adhesion via plasma membrane adhesion molecules	GO Biological Process Annotations 2015	1.0	null
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.869093
RAP2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8752
APBA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73436
CTCF_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213588_10_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4123
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056196
SATB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18576
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
SCC-25	COSMIC Cell Line Gene Mutation Profiles	1.0	null
smooth muscle	HPA Tissue Protein Expression Profiles	-1.0	-1.30659
hsa-miR-140-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
HCaRG_OE_GDS2426_711_human_HEK293 kidney cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SNU-182	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU201	CCLE Cell Line Gene Expression Profiles	1.0	2.30977
ventrolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.65381
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
GTEX-RWS6-0001-SM-3NMAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00412
TYK-NU.CP-R	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.896422
PMC11003700-pbio.3002240.s013.xlsx-siMYCN_RNA_IMR32_48h_q_0_05_1_5-Table_S6_Genes_commonly_and_differentially_regulated_by_MYCN_and_WDR5_in_IMR32_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM131L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40222
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01127
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RS4-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-3130-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77483
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
MYB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41047
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.924066
LRIG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90835
SCARF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13478
eye and adnexa disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.267977
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01066
Urinary bladder transitional cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.685
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36195
Sarcoma_SARC_TCGA-WK-A8XT-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.89774
EXOC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51413
TRMT9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.65783
NKAPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29678
CCND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4374
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10714175-mmc2.xlsx-KD_Gene_list-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PFKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27299
striatum_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06766
C11orf87	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98306
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04995
GTEX-S7SF-0001-SM-3K2BE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934537
H3K9me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF514	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.969
endometrium_8b	HPA Tissue Sample Gene Expression Profiles	1.0	1.03828
abducens nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.871083
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QMRM-0626-SM-447BQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910494
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW403	DepMap CRISPR Gene Dependency	1.0	2.38459
Prostate adenocarcinoma_PRAD_TCGA-VP-A87D-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A673	Achilles Cell Line Gene Essentiality Profiles	1.0	1.05059
JUND_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NAA80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68067
MAGOHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26018
PUF60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20862
G22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.928686
FLOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06219
GTEX-XPT6-0001-SM-4B64G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.932842
GSE149035_3_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HEK-293H cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.241
FZR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22105
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
RNF182	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38815
H3K9me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
NUP42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60224
MAP3K1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04707
Dosage compensation complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.585
PFKFB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62546
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
DB	DepMap CRISPR Gene Dependency	1.0	2.28053
GTEX-WWYW-0011-R5A-SM-3NB3E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844854
LITAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78608
Amylin receptor complex 1	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.209
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.976356
SREK1IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11414
YD8	CCLE Cell Line Gene CNV Profiles	1.0	2.48871
Silver-Russell syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.151
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GHITM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49951
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.875876
CTNND2	Pathway Commons Protein-Protein Interactions	1.0	null
CTCFL	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5031-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU3F2-20337985-501MEL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ITPRIPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07869
CTCF_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RNF126	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.11025
GTEX-SUCS-0008-SM-4DM53	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.825379
Prostate	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.42896
GSE178714_3_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TPCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.185
LNZTA3WT4	DepMap CRISPR Gene Dependency	1.0	3.18569
CTCF_GM12875_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
paravermis of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.959182
SNUC1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.40817
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.835608
SLC36A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46821
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A6MD-01A-41R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.27174
496100579_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.63193
SMC3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.21638
PMC8040704-jcav12p2673s2.xlsx-Down-regulated_genes_in_EBF1-Unnamed_5_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P78B-0826-SM-3NMCA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13241
MAP3K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.73323
SSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78645
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.89588
ELAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17023
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.26154
GTEX-WYVS-0006-SM-3NMA7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.924915
KG-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE140997_10_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
GSE148657_3_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CCDC127	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0715
UBFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79006
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.988208
GTEX-RVPV-0226-SM-2TF6W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990368
GSE140997_2_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PA-TU-8902	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S7SF-0008-SM-3NM8T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03708
H3K9me3_Rectal Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.998103
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
precuneus, right, superior lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.2789
HTR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9434
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
HS 69ST	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
EGR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16729
GTEX-N7MT-1026-SM-3TW8T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961448
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44314
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.66123
HIC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13008
ENTPD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22295
CPEB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67631
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0F7-01A-11R-A084-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE175787_8_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07425
GSE210101,GSE210114_6_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ARFGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4014
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.94123
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H650	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.950082
Hemoglobin H disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.014
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
ABL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20406
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.40243
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.916653
ARID3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95479
hsa-miR-3189-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periaqueductal gray substance, ventral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05755
locus ceruleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.65094
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
GTEX-PWOO-0008-SM-48TDU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892369
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.68083
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.97243
CORL51	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61509
MRPS34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54552
GSE214931_1_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NAA38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80978
EDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67639
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
RBBP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.089
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.379
SLC26A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18956
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4584
GSE140646_0_v_1_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8432
TE8	CCLE Cell Line Gene Expression Profiles	1.0	1.64973
TREX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90668
Lung adenocarcinoma_LUAD_TCGA-69-7980-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66236
GTEX-XV7Q-0626-SM-4BRV5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88411
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.16022
H3K9me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KLHDC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33418
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HC-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
EW-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BECKER	CCLE Cell Line Gene Expression Profiles	1.0	1.91525
CTCF_A549_hg19_10	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0643
GTEX-XQ3S-0001-SM-4B64K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
single organism signaling	GO Biological Process Annotations 2015	1.0	null
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.30248
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065987
EEIG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33414
NBDY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.31018
GSE249404_0_v_1_oxytocin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BHLHE23	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5871
PABPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91396
inner CP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.972853
SYT13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8566
hsa-miR-3935	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ6-0326-SM-3P61J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17533
carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070891
GSE214931_4_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.979525
TCCSUP	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-T6MN-1126-SM-4DM71	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23259
synaptic transmission	GO Biological Process Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61J-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
PMC9013128-NIHMS1795992-supplement-4.xlsx-SKmel147_ARID2_KO_Upregulated-Gene_name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-335-5p	MiRTarBase microRNA Targets	1.0	null
hsa-miR-1178	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
15902281-TableS1e	GeneSigDB Published Gene Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7220-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cohesin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.605
precommissural nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08239
claustrum, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.835103
GTEX-WYVS-2426-SM-3NMA9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848774
PANC-08-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of villous mesenchyme_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056432
FHIP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46976
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-XMD1-0011-R11A-SM-4AT5J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23329
GSE157609,GSE158123_0_v_1_ifi16_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-633	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
FBXL22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96241
CTCF_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPN-2826-SM-3LK67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01796
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
Mesothelioma_MESO_TCGA-MQ-A4LP-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MFE-280	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UBAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89016
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
RAD21_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4763-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Aflatoxin B1	CTD Gene-Chemical Interactions	1.0	null
ACADM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09221
CTCF_LNCaP clone FGC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.208
TBC1D2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50245
UBN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66564
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.50368
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23188
GTEX-T6MO-0626-SM-4DM6P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919077
CTCF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cadherin-like	InterPro Predicted Protein Domain Annotations	1.0	null
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.43812
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.835608
smc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.836
liver_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.06573
Brain Lower Grade Glioma_LGG_TCGA-DH-A7UU-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NO-10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8995879-Table_1.xlsx-exome_variants_MAF_0_01-Gencode_34_hugoSymbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
RPL18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55627
ALKBH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60795
hsa-miR-559	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
CYYR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18977
GTEX-WH7G-0626-SM-4LVMO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01892
GTEX-WRHU-1326-SM-4E3K7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876492
CTCF_MEL cell line_mm9_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.853332
PMC10510228-13287_2023_3481_MOESM7_ESM.xlsx-DEGs-Differentially_expressed_genes_DEGs_in_bone_marrow-derived_MSCs_from_six_human_donors_cultured_at_high_confluency_MSC-HC_versus_low_confluency_MSC-LC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28172
TSEN34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32855
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.93027
ZNF544	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37736
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.50466
LRRC57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73521
rostral group of intralaminar nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.901033
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.3264
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KG1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.61479
GNL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86045
principal sensory nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.32208
496100654_HIP_no dementia_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.11623
PMC6932815-ppat.1007634.s015.xlsx-ST5_DGE_ELF1-R8AvIFN48-mock_lfc-external_gene_name_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
POLR2A	ENCODE Transcription Factor Targets	1.0	null
PMC8185471-mmc4.xlsx-D4-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_4_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
MRPL35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88123
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.51266
MAN2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1194
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02198
UBXN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58143
HSPB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53726
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE221327_8_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
PHLPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8616
GTEX-TKQ2-0004-SM-3NMAC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00936
NATD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78399
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067078
NR3C1	JASPAR Predicted Transcription Factor Targets	1.0	null
SART3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14623
CCDC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74537
DNAJC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89372
SIVA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29925
medial group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12941
CTCF_retinal pigment epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0011-R6a-SM-2HMJ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4392
GSE168587,GSE168752_3_v_1_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
DSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17428
GSE120612_6_v_3_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CPNE7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28415
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
15735024-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
MCC26	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE96777,GSE96778_3_v_2_zbtb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
WM-239 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.293
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.50982
PMC5798892-41421_2017_3_MOESM7_ESM.xlsx-TM_KO_vs_WT-Supplementary_Table_S2-2_Up-_and_downregulated_genes_in_ATF6_cells_relative_to_ATF6_cells_in_the_presence_of_TM_early_passage_ATF6	Rummagene Transcription Factor Associations 2026	1.0	null
LC1SQSF	CCLE Cell Line Gene CNV Profiles	1.0	2.0233
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9443
HAND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39704
CTCF_GM12874_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01066
GTEX-TKQ1-0003-SM-3NMAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
NACC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7458
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6013-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07343
CTCF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
BICR 10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05758
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06342
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral orbital frontal cortex (area 12/47)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.74995
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05772
Colon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.157
CDC26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10878
Kidney renal clear cell carcinoma_KIRC_TCGA-EU-5905-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14518
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05076
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NN-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BXPC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE139540_4_v_1_menadione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q4-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUFIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1305
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.17939
SC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
substantia nigra, pars compacta, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.44701
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.906589
RTN4IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88166
HCC1419	DepMap CRISPR Gene Dependency	1.0	2.30642
nervous system development	GO Biological Process Annotations 2023	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M7-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skov-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.728152
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052336
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.484
FARAGE	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6649
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.867224
GTEX-XV7Q-0526-SM-4BRWR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15436
GSE238018_1_v_5_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5101
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YI-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_Caco-2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.06675
NALM-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.098
SCRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25042
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.64243
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
WDR26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30413
ALDH5A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13697
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
5637	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-4698	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
FRA10AC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62106
PBX1	ChEA Transcription Factor Targets	1.0	null
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q1-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
GSE216540_10_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCC021	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H2023	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.16073
GTEX-P4PP-0426-SM-3NM9H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28866
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.916058
ATPAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22595
dorsolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03896
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80V-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBPJL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72889
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17064
GTEX-UTHO-3126-SM-3P5ZB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883992
GTEX-OIZI-0005-SM-2XCED	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.932098
JMJD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27113
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.825859
ETV2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2978
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6196
RAD21_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RNF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9765
Perturb_354_OE_MITF_SRP298756	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
LN-229	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07134
Brain Lower Grade Glioma_LGG_TCGA-HT-7687-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05836
C1orf56	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67029
WIPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23241
brain_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.3536
GSE143782_3_v_11_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
tonsil	HPA Tissue Protein Expression Profiles	-1.0	-0.842423
stratum pyramidale of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16708
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GSE140997_4_v_3_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
MDAMB157	CCLE Cell Line Gene CNV Profiles	1.0	2.17112
CTCF_HEK293_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V1D1-0003-SM-3NMDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02369
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58805
MCAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67518
ovary adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.658272
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
rnf2_20805357_u2os_osteosarcoma_lof_human_gpl570_gse23035	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.405204
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.950396
Lung adenocarcinoma_LUAD_TCGA-55-8207-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferior olive, dorsal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14437
PCDH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01604
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4UY-1226-SM-4AD51	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899754
CTCF_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RNOR-2426-SM-48FDY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59473
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20T-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YKG1	CCLE Cell Line Gene Expression Profiles	1.0	1.40217
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YT-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
Prostate adenocarcinoma_PRAD_TCGA-KK-A7B3-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JAM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02177
CTCF_GM12864_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
GTEX-QXCU-0126-SM-2TC5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853936
lymph node	HPA Tissue Protein Expression Profiles	-1.0	-1.30659
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.969914
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937496
OVTOKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.48751
prostate gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.099312
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895265
RNASE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37727
CTCF_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R53T-0326-SM-48FEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0398
PARP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03587
496100582_HIP_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.18394
H3K9me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.857849
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.09441
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65243
LC1F	CCLE Cell Line Gene CNV Profiles	1.0	1.50785
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16224
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
KP4	Achilles Cell Line Gene Essentiality Profiles	1.0	1.29597
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.30366
SUM1315MO2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.75379
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.5936
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29585
psn1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.132
GFY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88334
ovary cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.122657
TOMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55319
MICA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78811
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CENPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15437
GATA3	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
RAD21_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96638
DIPK2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34465
cuneus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.53248
OVOL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42741
ASXL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37188
KU-19-19	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ORMDL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99664
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.896446
a431	HPA Cell Line Gene Expression Profiles	-1.0	-1.28527
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HH-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43466
GSE219195_1_v_3_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4899-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-2665-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AP4M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53334
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.29
OCIAML2	Achilles Cell Line Gene Essentiality Profiles	1.0	1.20818
15656903-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
DHRS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63573
GTEX-QXCU-0926-SM-48FEP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45378
GTEX-Q2AG-0926-SM-48U1Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85281
PMC10111863-supp_gad.350269.122_Supplemental_Paun350269_FileS3.xlsx-A_ASCL1-regulated_DGE-geneID_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
EGFR	Pathway Commons Protein-Protein Interactions	1.0	null
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.901898
HCC1395	CCLE Cell Line Gene Expression Profiles	1.0	1.41095
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09989
KLK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77323
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19362
CEMIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81972
PRSS50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89655
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05973
MUSTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62247
oncostatin-M receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.296
Pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.404
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33422
GTEX-T6MO-1526-SM-4DM57	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834428
DAB2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52695
GTEX-XOT4-0426-SM-4B66T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894375
internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
VMRCLCD	DepMap CRISPR Gene Dependency	1.0	2.26072
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPN-0011-R11A-SM-2I5FM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03486
metal ion binding	GO Molecular Function Annotations 2015	1.0	null
SW626	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
Brain Lower Grade Glioma_LGG_TCGA-QH-A65Z-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09086
HOPX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89516
GSE239844_6_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCT 116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04265
Digestive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.157
SNU349	CCLE Cell Line Gene Expression Profiles	1.0	3.17126
CHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00446
GSE142210_3_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A23B-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cuneus, right, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.78539
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
PURB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26
RCOR1	ENCODE Transcription Factor Targets	1.0	null
CSNK2B	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.855227
NCI-H2347	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.35995
GTEX-XYKS-0002-SM-4BRWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
GSE225901_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.157
PIAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46308
CTCF	ENCODE Transcription Factor Targets	1.0	null
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19982
GTEX-REY6-0926-SM-48FDA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860221
EEF1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2911
EED	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41254
TMEM265	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58542
STK26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17161
NEFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72945
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.0859
PGK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77099
EP300	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.63332
RPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28041
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.4983
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.68083
PMC7439574-13148_2020_914_MOESM2_ESM.xlsx-log2_fold_change_-2-1280_genes_are_more_than_four-fold_downregulated_in_PRDM8-_-_compared_to_control_PRDM8	Rummagene Transcription Factor Associations 2026	1.0	null
OACP4C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RPUSD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13238
CTCF_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ALAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01487
B4GALT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83391
Calcitonin family receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.932
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.3854
ovary cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.519647
MCIDAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48644
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.211
PMC9992472-41467_2023_36735_MOESM5_ESM.xlsx-SOX11_OE_9h_in_SH-EP-Unnamed_7_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
GRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87843
breast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068645
hsa-miR-548i	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
PARP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56103
MRPL24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24204
MV411	Achilles Cell Line Gene Essentiality Profiles	1.0	1.12292
CCNE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61545
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.86396
KELLY	CCLE Cell Line Gene Expression Profiles	1.0	1.61123
smooth muscle	HPA Tissue Gene Expression Profiles	1.0	0.95217
POLDIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26303
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.20334
AUTS2-25519132-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7327-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45218
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8178
MYCN-21190229-SHEP-21N-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUZC-0926-SM-4BOQF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10478
GSE133763_0_v_2_chd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAP3K7_knockdown_37_GDS5023	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	0.876213
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8098-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
stratum oriens of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31891
MCF10DCIS.COM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17461
CTCF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RUSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30426
KG1C	CCLE Cell Line Gene CNV Profiles	1.0	1.48882
ID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31874
Brain Lower Grade Glioma_LGG_TCGA-QH-A65R-01A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873086
GSE201309_1_v_8_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20X-01A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18051
cuneate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.989241
MAGEL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63785
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A68B-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of mammary gland_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GMPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85234
GTEX-VUSG-0526-SM-4KL22	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55942
hsa-miR-3613-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.94186
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.34359
PQBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39178
TFRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28262
A-CA-04-2009(H1N1)_3Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.3399
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I2-06A-21R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01435
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.24941
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.49306
NCI-H1623	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CSNK2A1	Pathway Commons Protein-Protein Interactions	1.0	null
ZSCAN31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30356
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78N-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Pectoral fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.668
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.92484
GSE178907_0_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-WH-A86K-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HAGHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48327
GSE111247_14_v_12_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HLTF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40956
MOLM16	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42196
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.8645
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A42R-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF354C	JASPAR Predicted Transcription Factor Targets	1.0	null
AMER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23442
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MYCN-27167114-CHIP-SEQ-NEUROBLASTOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7424-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATOH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12373
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-WYVS-2526-SM-3NMAT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27735
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.1266
OVCAR-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00486
GTEX-U8XE-1226-SM-4E3HN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21123
GTEX-WHPG-0004-SM-3NMDO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.880385
TOV-21G	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-64-5774-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NH6	CCLE Cell Line Gene Expression Profiles	1.0	2.09649
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
GSE117212,GSE117214_0_v_1_zbtb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07076
Brain Lower Grade Glioma_LGG_TCGA-HW-8322-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LRRC32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52963
ZSCAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21747
MDAMB436	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.05955
TK-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30712
CCDC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08739
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14518
PPP2R3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93935
GSE118077_1_v_8_sprr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100607_TCx_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.06037
KYAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30474
GTEX-U8XE-0005-SM-3DB8I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
SR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55468
CIAO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76395
Prostate adenocarcinoma_PRAD_TCGA-HC-A8CY-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell-cell signaling	GO Biological Process Annotations 2015	1.0	null
calcium ion binding	GO Molecular Function Annotations 2015	1.0	null
mediodorsal nucleus of thalamus_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.831954
GTEX-PX3G-2026-SM-48U1H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.96903
CPNE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.786
Acute Myeloid Leukemia_LAML_TCGA-AB-2917-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CISH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75015
parataenial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.889105
DIFI	DepMap CRISPR Gene Dependency	1.0	4.50159
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7698
PMC12179407-MCO2-6-e70261-s004.xlsx-up_TET3-KO_PQ_vs_Cas9_PQ-Unnamed_10_TET3	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF704	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09562
STX12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71861
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100445_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.03292
PLA2G4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23469
NCIH1836	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34252
EZH2	ENCODE Transcription Factor Targets	1.0	null
inner CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00818
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.962007
HUH-6-CLONE5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PX3G-0008-SM-48U2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.864234
JAR	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-SIU7-0001-SM-3NMAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.882808
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.990835
NB7	DepMap CRISPR Gene Dependency	1.0	5.36968
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.139
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.74276
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LE-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-V1D1-0008-SM-4JBIJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86675
LOUCY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
psi2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.632
PACC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46663
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.03701
TRPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45897
MOGGCCM	CCLE Cell Line Gene Expression Profiles	1.0	1.38663
CTCF_foreskin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE178714_3_v_4_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
OSBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43868
SMC3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24321
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65348
NUP205	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59674
PAQR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41274
SKCO1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.73735
ADAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21504
outer CP in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31566
LENG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37492
MTRES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07783
signaling	GO Biological Process Annotations 2015	1.0	null
NKRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93395
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.871176
NIF3L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.76679
SNRPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56577
TRIM27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6881
SGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80324
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	114.844
NCIH1993	DepMap CRISPR Gene Dependency	1.0	3.4026
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7374-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular component assembly	GO Biological Process Annotations 2015	1.0	null
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.1865
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01521
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3707
GTEX-SNMC-0008-SM-4DM5A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7430-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pc-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.53267
ATAD3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34915
ERGIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75805
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.8838
496100639_TCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.47403
HES7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51707
HS729	DepMap CRISPR Gene Dependency	1.0	2.01804
GSE201309_5_v_8_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
RNF220	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57733
CTCF_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-W3-A824-06A-21R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.09434
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
GTEX-OIZG-0005-SM-2HMJC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34509
hsa-miR-203	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
PMC7857731-elife-63093-supp5.xlsx-ECMdegs-pB-MITF-FLAGvs_pB-FLAG-Unnamed_3_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1304
GTEX-O5YV-0626-SM-3LK64	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12717
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6797-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74555
H3K9me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SPARC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43192
G59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.988267
VZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.902432
CTCF_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
OAW42	DepMap CRISPR Gene Dependency	1.0	7.23196
Corpus callosum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.316
FEM1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21318
HMGB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11614
AU565	CCLE Cell Line Gene CNV Profiles	1.0	1.41392
Lung squamous cell carcinoma_LUSC_TCGA-43-5670-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF865	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99835
Brain Lower Grade Glioma_LGG_TCGA-DU-6393-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
endometrium_8a	HPA Tissue Sample Gene Expression Profiles	1.0	0.824069
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08499
PMC10149505-41392_2023_1393_MOESM2_ESM.xlsx-CPCMR-Hugo_Symbol_MEIS2	Rummagene Transcription Factor Associations 2026	1.0	null
SPRED3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31735
NMRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09183
IFT20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34888
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.9993
OLIG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4971
496100335_PCx_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2538
ovary cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.361527
GSE195559_6_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TRIM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58698
TCF23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64019
GTEX-XUYS-0005-SM-47JZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904722
GNA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72808
GSE158320,GSE183351_2_v_3_lin28b_human	RummaGEO Gene Perturbation Signatures	1.0	null
KMS34	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62166
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895009
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9603
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_6906_KD_DDR1_SRP334383	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.01882
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4907-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BE2-M17	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE139016_0_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837399
prostate_a	HPA Tissue Sample Gene Expression Profiles	1.0	0.92123
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2716
oculomotor nuclear complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.45742
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5675-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T2IS-1126-SM-4DM6Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957231
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879805
127399	DepMap CRISPR Gene Dependency	1.0	3.37153
GTEX-PX3G-0006-SM-33HBQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.87076
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.64171
CTCF_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SEC14L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.69977
SAMHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9993
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
CTCF_MCF-7_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.827178
CTCF-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-POYW-0006-SM-2XCF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
496100656_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07118
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-IF-A3RQ-01A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JVM-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-329	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GTEX-X585-0011-R3B-SM-46MVG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853459
sirolimus_homo sapiens_gpl6244_gse15703	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6724
GSE168233_0_v_1_setdb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-A4QQ-01A-41R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
EFCAB14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27801
GTEX-SIU8-0426-SM-4BRUE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01243
PLEKHG4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11155
HS 69ST	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.22975
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07529
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.918691
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3MA-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT3	JASPAR Predicted Transcription Factor Targets	1.0	null
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055671
GSE230263,GSE230265_0_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Autonomic nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.147
lingual gyrus, right, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08184
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.56448
JIMT-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
11823860-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
Sarcoma_SARC_TCGA-DX-A8BT-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OS252	DepMap CRISPR Gene Dependency	1.0	3.77493
ZNF526	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31297
PUM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46478
posteroventral (inferior) parietal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10151
GDM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25211
GSE221327_8_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
TRPC4AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2479
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.84555
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.262
GSE139455_4_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.856138
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
synapse assembly	GO Biological Process Annotations 2025	1.0	null
GTEX-R55E-1126-SM-48FDZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0736
TCL1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26253
GTEX-NPJ7-0011-R10A-SM-2I3E5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23453
CCDC74B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69408
PTPN1	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21987
hsa-miR-3926	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.21973
KLF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41124
CALB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42463
LARP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85863
GSE205163,GSE205164_2_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.38221
SPIRE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3488
GTEX-QVUS-0008-SM-447AY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.921122
PRRT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43359
GTEX-U3ZH-0626-SM-4DXT3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28595
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7685
medial geniculate complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.8996
SF126	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S33H-0726-SM-4AD6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89175
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06643
UQCC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67624
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5229
CTCF_fibroblast of lung_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34746
REST-19997604-NEURONS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.72218
TRIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04108
DFFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03951
TBC1D15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52284
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NPJ8-0011-R6a-SM-2HMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26526
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GSE135352_0_v_3_napabucasin_human	RummaGEO Drug Perturbation Signatures	1.0	null
DPPA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78154
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.45766
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DNAL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17391
GTEX-S3XE-0826-SM-4AD4U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03442
SHMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15462
GSE210101,GSE210114_8_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23696
LN235	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.97981
SNUC1	DepMap CRISPR Gene Dependency	1.0	6.8889
TOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32238
primary motor cortex (area M1, area 4)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.893335
GTEX-NPJ8-0526-SM-3MJHN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899053
EFO-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.16073
PRR35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4966
NCCSTCK140	CCLE Cell Line Gene CNV Profiles	-1.0	-1.81735
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9151
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
GTEX-NPJ7-0011-R8a-SM-2I3G2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02193
PMC7880998-41467_2021_21255_MOESM8_ESM.xlsx-Sup_Data_5_TWIST_Panel-Gene_Name_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.236
Birk-Barel syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
MAP2K7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95595
RGMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10718
SLC25A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76046
GSE178714_1_v_4_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7478-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00519
GSE210388_2_v_0_ror2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Embryonic brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.451
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.77362
REST	ChEA Transcription Factor Targets	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U9-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.914057
M14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2AphosphoS5_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
PGBD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28769
BSPRY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82643
HCC44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.08072
Acute Myeloid Leukemia_LAML_TCGA-AB-2849-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NALM-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.855707
POLE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8369
HELB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56073
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5921
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70V-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
22RV1	DepMap CRISPR Gene Dependency	1.0	7.23931
CTCF-33576154-HUMAN-PERIGASTRICLN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
SR-786	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43466
hsa-miR-4330	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-NPJ7-2826-SM-2I3FU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03249
Sarcoma_SARC_TCGA-X6-A7WC-01A-12R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2703
COR-L32	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
PCF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41587
FGD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27376
CLPTM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39108
LRRC37B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34137
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1114
CTCF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lower (caudal) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.6317
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044632
CHSY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47385
HCC78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.918089
subgranular zone of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.89184
duodenum	HPA Tissue Protein Expression Profiles	1.0	1.86497
GTEX-WWYW-0011-R10A-SM-3NB35	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10642
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XN-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAFK	ENCODE Transcription Factor Targets	1.0	null
YARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09631
GSE135030_8_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
LARGE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92441
C4orf48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63872
IA-LM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SRF	JASPAR Predicted Transcription Factor Targets	1.0	null
ECC10	CCLE Cell Line Gene CNV Profiles	-1.0	-1.84618
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0022
GSE195559_2_v_7_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FLNC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71467
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.18335
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM121B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98126
Calcium	HMDB Metabolites of Enzymes	1.0	null
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.48054
FNBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55131
SNB75	DepMap CRISPR Gene Dependency	1.0	3.18989
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5007-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LRRC40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41701
H3K9me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH1648	CCLE Cell Line Gene CNV Profiles	1.0	1.52597
KP2	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.00422
CTCF_BE2C_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8040704-jcav12p2673s2.xlsx-Down-regulated_genes_in_EBF1-Unnamed_0_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
ACTR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51934
TCF7L2_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE245270_2_v_5_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
SU-DHL-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00701
PRMT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94588
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.896562
CPT1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37841
OAW42	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30526
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.793772
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45364
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
TMEM87B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38881
prostate cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.320591
H3K9me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85864
CTCF_GM12865_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R53T-0726-SM-48FCS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946435
CTCF_fibroblast of the aortic adventitia_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Breast - Mammary Tissue	GTEx Tissue Gene Expression Profiles 2023	1.0	2.18985
GSE140441_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
GSE178714_3_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-5304-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-155	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
SYNJ2BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35357
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.83269
PSPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12143
PEX11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57445
PMC7857731-elife-63093-supp5.xlsx-ECMdegs-pB-MITF-FLAGvs_pB-FLAG-Unnamed_4_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	GO Biological Process Annotations 2023	1.0	null
CTCF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.259
CTCF_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DUSP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95905
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.30368
Lung squamous cell carcinoma_LUSC_TCGA-NK-A5D1-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHP126	CCLE Cell Line Gene Expression Profiles	1.0	2.57164
ROR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48609
CTCF_cardiac muscle cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HT3	DepMap CRISPR Gene Dependency	1.0	2.56003
striatum_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.848557
PMC12179525-mmc1.xlsx-Group_HNF4A_vs_Null_sign-Supplemental_Table_S1_Differentially_expressed_genes_in_HNF4A-transduced_cells_vs_Null_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
BORCS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5594
MECP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30812
QGP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.863454
GSE222758_0_v_3_clofazimine_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SJCRH30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.52075
HEL9217	DepMap CRISPR Gene Dependency	1.0	3.72131
N4BP2L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89074
BGN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82234
LN319	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.50095
ZNF703	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34724
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.389
HDAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11418
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.72362
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040611
SLC35E2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99882
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
CAPAN1	DepMap CRISPR Gene Dependency	1.0	7.77103
MCRIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74349
GSE140997_4_v_6_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.837787
GTEX-T6MN-0002-SM-3NMAH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.882311
RNF115	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37104
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
KNS81	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.26723
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06259
ZNF771	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84775
ISL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27115
TPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54361
FAM204A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40612
Autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.4
male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
ovary	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.096745
HS343T	CCLE Cell Line Gene CNV Profiles	-1.0	-2.07898
RCC4	CCLE Cell Line Gene CNV Profiles	1.0	1.82416
ARHGEF39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79003
hsa-miR-4708-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
CTCF_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4480	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2913-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE235550_2_v_0_hspa9_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10714175-mmc2.xlsx-KD_Gene_list-Supplemental_Table_3_FAM13B_knockdown_mediated_changes_in_gene_expression_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
GSE172494_3_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HS 852.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.856703
Lung adenocarcinoma_LUAD_TCGA-78-7537-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5458-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATXN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0325
hel	HPA Cell Line Gene Expression Profiles	-1.0	-1.28527
GSE178714_3_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K9me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Cadherin signaling pathway	PANTHER Pathways	1.0	null
Dyslexia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.124
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.28686
GSE122425_1_v_0_nsun2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PDGFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88412
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65243
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
P2RY11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07334
hypoglossal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.54103
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.68904
ZNF431	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41224
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.44
upper (rostral) rhombic lip_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.966624
RER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58459
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QV44-2226-SM-447A3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878259
membrane part	GO Cellular Component Annotations 2015	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7836-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12871_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNRNPD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84097
cell-cell adhesion via plasma-membrane adhesion molecules	GO Biological Process Annotations 2015	1.0	null
ERVV-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69601
FAM117A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42889
GOSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05725
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.83198
Lung adenocarcinoma_LUAD_TCGA-J2-8192-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3763
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33177
KLF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02344
FOXB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21957
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.895092
SIMA	CCLE Cell Line Gene Expression Profiles	1.0	1.36257
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
ATP11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56851
ZNF428	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57471
MICALL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2718
GSE220668_0_v_1_ncapg_human	RummaGEO Gene Perturbation Signatures	1.0	null
COV-644	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.966
RAD21_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATP5F1E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48916
GSE202434,GSE202438_8_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-VUSG-0626-SM-4KL1Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85807
Reading disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.12
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
cetuximab_homo sapiens_gpl570_gse21483	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.924217
NCI-H647	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2804	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5383
GTEX-P4PQ-0426-SM-3NMCI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02407
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4986-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HT-29	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HSFX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88967
CTCF_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RNF166	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10858
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11285
GOS3	CCLE Cell Line Gene Expression Profiles	1.0	1.95331
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.03053
CTCF_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SJXC-1226-SM-4DM78	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.912881
JMY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57921
COLO-668	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NALF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69212
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5201-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE152699,GSE152723_0_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
CTCF_astrocyte of the spinal cord_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DDHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67607
GSE140997_4_v_5_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A42K-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65543
17699763-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.916598
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
PLCB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45086
A388	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CLIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.59221
GTEX-R53T-2026-SM-3GIJF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945805
GSE176144_0_v_1_zfc3h1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CFAP97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53086
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3HU-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARMC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67096
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06937
CCRF-SB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.68584
MTFR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65547
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6936-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CALD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51855
SLC38A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58192
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_ID_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
OCI-LY7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.999485
GTEx Muscle 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	17.1224
adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.088285
gallbladder	HPA Tissue Protein Expression Profiles	1.0	1.86497
GTEX-S95S-0002-SM-3NM8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00322
NCIH647	DepMap CRISPR Gene Dependency	1.0	2.24171
AGMAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66048
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.08331
TBX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1418
GSE235066_7_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.979166
COR-L105	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endometrium_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.60816
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7371-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DNAJA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1059
CTCF_GM12868_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GOLPH3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25121
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27531
GDI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50421
MDM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10934
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6935-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H630	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CDX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3395
SLC35A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49488
C2orf81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11998
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HIF-2alpha_DEPLETION_GDS2760_643_human_Hypoxic MCF-7 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Mesothelioma_MESO_TCGA-MQ-A4LI-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.45723
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFJO-0002-SM-3P61X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02121
RAD21_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WEY5-0726-SM-4LMID	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908623
SF295	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01521
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063083
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-8175-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67865
GSE227698_2_v_4_g0s2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29W-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01386
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q5-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
SYT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83302
PPP1R11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64414
DHCR24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85564
SLC7A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77075
cellular component organization	GO Biological Process Annotations 2015	1.0	null
Cornified envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.728
FGFR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1536
GTEX-S33H-2426-SM-2XCB2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927006
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.945943
PMC9305137-PATH-256-297-s005.xlsx-CIC_associated_DE_genes_IDH1-W-Unnamed_1_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
INAVA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80292
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
GCNT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01534
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5984-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COL6A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34942
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.872263
GTEX-P44H-1026-SM-3NM96	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0471
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
CTNND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73377
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
GTEX-QEG5-1226-SM-447AR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77939
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.909681
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06259
DGKZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98087
STX1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34673
LNX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35106
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.699439
GTEX-TKQ2-0008-SM-4DM5L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840726
CTCF_GM12869_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01386
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7253-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I8-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE176008_0_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
CI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.986354
PRDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07142
Prostate adenocarcinoma_PRAD_TCGA-XQ-A8TA-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE147366_1_v_4_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE220806_1_v_3_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S7SE-0005-SM-2XCEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.928835
REEP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05389
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.857122
CTCF_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21386
NOP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82855
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A5RJ-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE238018_1_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6983-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TPM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86611
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8392
PMC11585558-41467_2024_54547_MOESM8_ESM.xlsx-TP53_vs_WT_DEG_FFPE-gene_name_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_3664_KD_RBM27_SRP243927	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTF2IRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08642
RAB3IL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08385
PTGER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70273
synapse organization	GO Biological Process Annotations 2025	1.0	null
KPNYS	DepMap CRISPR Gene Dependency	1.0	4.8848
GSE258991_5_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NALM1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.26568
CFLAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26602
ORC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47841
GTEX-RWSA-0926-SM-47JXW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2252
PMC2866657-pone.0010547.s003.xls-ERG_corr-Genes_correlated_anticorrelated_to_ERG_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
GSE176008_4_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.97088
IKBKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24152
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.84938
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13097
ZNF281	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42152
medial group of nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17146
NUGC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061274
SK-UT-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PHF20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01861
D341MED	CCLE Cell Line Gene Expression Profiles	1.0	1.47461
PMM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32597
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7261-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HDHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1754
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0011-R10A-SM-2HMLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42863
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
FGFR3_KD_GDS4454_78_human_RT112	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YD-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NPTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43121
C11orf24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82446
GTEX-TML8-0001-SM-3NMAF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
SAGA-type complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.211
CTCF_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070009
NCIH2171	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32679
NGFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52199
SLC26A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65616
CTCF_GM12872_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02848
TLDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03795
BCAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16641
PMC4266008-mmc3.xlsx-iPS-MSC_vs_MSC-Unnamed_1_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
C-33-A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WRHU-1126-SM-4E3I1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13607
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32407
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.999462
hsa-miR-548s	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GTEX-XBED-0003-SM-47JWP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.971723
GTEX-S95S-0226-SM-4B656	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948273
HCC56	DepMap CRISPR Gene Dependency	1.0	2.41387
cellular component organization or biogenesis	GO Biological Process Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7418-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
INCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86595
ERG-21242973-JURKAT-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
GMFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33041
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55G-0626-SM-48FDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72013
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.37444
paraventricular nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05751
BRAF_druginhibition_38_GDS5085	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.62098
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0225
MSH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25366
ZNF99	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70835
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3N6-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain - Cerebellum	GTEx Tissue Gene Expression Profiles 2023	1.0	2.25478
CORL279	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35408
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.867609
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.28911
M07E	CCLE Cell Line Gene CNV Profiles	-1.0	-2.95159
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GD-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_MCF-7_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Distal-RefSeq_Name_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE140997_4_v_8_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
ES1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9074
IMPACT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77186
NEURL1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66833
STEAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30026
CYTH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97257
624 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10552
SPRYD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48724
GTEX-PLZ6-0008-SM-48TD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.824125
Cadherin	InterPro Predicted Protein Domain Annotations	1.0	null
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RASD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37348
SUMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06837
OCI-AML5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02417
GJA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22883
KNS81	CCLE Cell Line Gene Expression Profiles	1.0	1.73996
internal segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.856323
SRP54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21008
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJHI-0326-SM-4IHJE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02882
GSE77108_5_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF	ChEA Transcription Factor Targets	1.0	null
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43813
hsa-miR-548d-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A897-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE238018_3_v_0_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1657
ZC3HAV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98708
ETS1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLB985	CCLE Cell Line Gene CNV Profiles	1.0	1.37271
GTEX-WVLH-3126-SM-3MJGA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0081
TTLL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03314
IFI35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4339
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	108.51
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6950-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G-401	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NR5A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68348
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.917387
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.994422
PMC5687749-pone.0188272.s005.xlsx-Supplementary_Table_3-Supplementary_Table_3_Differentially_Expressed_Genes_in_Common_between_AFX_compared_to_both_Keratinocytes_and_Fibroblasts_FOXO4	Rummagene Transcription Factor Associations 2026	1.0	null
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.918072
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.899902
Uterine endometrium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.157
BTBD18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.71501
Lung squamous cell carcinoma_LUSC_TCGA-92-8065-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-69-7764-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HL-60	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.813
BRSK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90723
MCM3AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32819
CTCF_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_epithelial cell of esophagus_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMR6-0011-R6A-SM-32PKP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11847
GTEX-Q2AG-3026-SM-48U1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72301
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060823
Brain - Cortex	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.580529
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
WASHC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02901
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73R-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral group of nuclei, left, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11668
NCIH1963	CCLE Cell Line Gene CNV Profiles	-1.0	-2.20396
GTEX-WHWD-2426-SM-3LK6S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829108
CTCF_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
GTEX-TMZS-0001-SM-3P61Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
SPNS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40605
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.89861
Prostate adenocarcinoma_PRAD_TCGA-J9-A52B-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM101	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34565
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.835608
TPI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62999
KPNRTBM1	CCLE Cell Line Gene Expression Profiles	1.0	1.91179
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fulvestrant_homo sapiens_gpl570_gse22533	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7434
SEMA3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56923
PMC10864182-41588_2023_1596_MOESM4_ESM.xlsx-ST12_Significant_Genes_combine-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
H1-6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17592
CCK-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
U251MG	CCLE Cell Line Gene Expression Profiles	1.0	1.61486
ARHGEF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97919
ZC3H13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87998
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.977866
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060521
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.866382
MYRFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.0212
GSE211262,GSE211263_0_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.993806
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
SLC16A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16747
SPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26462
GSE113817_0_v_1_bach1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PJVK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61496
GTEX-T5JC-0001-SM-3NMAK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
Prostate adenocarcinoma_PRAD_TCGA-HC-7230-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MFSD14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55184
ERBB3	Pathway Commons Protein-Protein Interactions	1.0	null
RNF185	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85169
NCI-H1876	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TWIST1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5321
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
CUL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04219
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.4006
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
posteroventral (inferior) parietal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.904463
GTEx AdiposeTissue 20-29 vs 40-49	GTEx Tissue-Specific Aging Signatures	1.0	5.69265
breast adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.226155
EXOSC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40101
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1ML-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.891726
REST-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC7680901-Table_6.xlsx-both_up_GSE117165-SETBP1_SETBP1	Rummagene Transcription Factor Associations 2026	1.0	null
outer CP in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04891
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	GO Biological Process Annotations 2015	1.0	null
ATXN7L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91451
Prostate adenocarcinoma_PRAD_TCGA-WW-A8ZI-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-N7MS-2625-SM-3LK77	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96336
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.86563
ONS76	CCLE Cell Line Gene Expression Profiles	1.0	1.60692
MDAMB361	DepMap CRISPR Gene Dependency	1.0	7.52098
16135788-Table13	GeneSigDB Published Gene Signatures	1.0	null
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7437-01A-21R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BTG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80699
RMDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80291
TMEM104	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94861
ST486	COSMIC Cell Line Gene Mutation Profiles	1.0	null
eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.271886
GTEX-WYVS-1726-SM-3NMAY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874378
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-0011-R6A-SM-4AT4B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23486
CALU-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.840115
FANCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59459
Renal medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.651
WWC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24497
Spinal cord	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.253
doxorubicin_homo sapiens_gpl6947_gse25741	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8731
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
KRT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40015
BRI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44594
Lung squamous cell carcinoma_LUSC_TCGA-56-8309-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLEKHO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64746
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6135-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCaRG_OE_GDS1411_72_human_HEK293 embryonal kidney cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
293-F FreeStyle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.055
membrane	GO Cellular Component Annotations 2015	1.0	null
MMP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41682
mediodorsal nucleus of thalamus_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.83027
synapse organization	GO Biological Process Annotations 2023	1.0	null
LUZP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61949
biological adhesion	GO Biological Process Annotations 2015	1.0	null
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.66773
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.37113
DCPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72681
STOM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08361
SBC-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-N7MT-0011-R6a-SM-2I3G3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936414
GSE175787_4_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TYK-NU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052337
NOBOX	JASPAR Predicted Transcription Factor Targets	1.0	null
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.098
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16399
SK-LMS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF382	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15413
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.65772
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A5RH-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell junction assembly	GO Biological Process Annotations 2025	1.0	null
TMEM184C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92719
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.862024
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.061
DMS79	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52819
BECN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03728
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	100.833
GNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50999
gracile nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06347
INO80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73858
UNC5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.02985
GAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44483
CASTOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01382
GTEX-R55F-1726-SM-2TF4R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987717
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CTCF_WI38_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846258
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-CoV_12Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.14217
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
BHLHA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53005
Parietal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.392
COLO 205	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.835608
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8567138-Table_2.xlsx-Sheet1-IGFBP5_AND_IGFBP7_NOT_IGFBP3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.996247
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.62405
CTCF_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EIF2AK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71722
NCI-H2373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.23012
hsa-miR-548ab	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0129
KPNA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93341
AK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48473
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A68F-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rostral group of intralaminar nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.36368
TSEN54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29179
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.18706
Prostate adenocarcinoma_PRAD_TCGA-CH-5769-11A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.953609
ZNF774	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71403
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IJ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01066
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SP-01B-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9902
SKNBE2	CCLE Cell Line Gene Expression Profiles	1.0	1.40299
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23319
Perturb_2630_OE_ROR2_SRP293436	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
HEK-293F cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.64
ZNF266	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70568
CP in retrosplenial cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17169
JHOM1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.0868
tonsil_8e1	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.983638
RNF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57431
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.928928
HK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26619
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.90706
Mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.157
mRNA_JARID2_20075857	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35898
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IR-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SYNRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88033
NCI-H1963	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.13481
RELL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32824
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
IGF2BP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94152
lateral group of nuclei, right, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03438
CTCF_CH12.LX_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
epididymis	HPA Tissue Protein Expression Profiles	1.0	1.86497
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Bgm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.543
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07637
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16568
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZMIZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86025
GSE176008_4_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TAOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65264
CTCF_GM12864_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.50933
PPP1R7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17479
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QA-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DENND10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97604
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7445
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.97063
GSE76425_0_v_7_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SET2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.99148
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27229
CTCF_GM12872_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.3478
hsa-miR-3978	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
RAD21_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
craniofacial-deafness-hand syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.362
CTCF_GM12874_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.61337
DBNDD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78191
SP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.917292
NPAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43047
GTEX-POMQ-0426-SM-3P61G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39448
ZNF432	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51916
brain_3b	HPA Tissue Sample Gene Expression Profiles	1.0	2.18767
GSE168401_2_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5752-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-407	COSMIC Cell Line Gene Mutation Profiles	1.0	null
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-0.945981
CIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38088
PMC2866657-pone.0010547.s001.xls-ERG-high-GENES_UPREGULATED_IN_ERGhigh_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
ets_00000000_2008_ovarian_cancer_cells_gof_human_gpl6244_gse21129	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.279521
WM-115 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.021
Bacterial nucleoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.876
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.8309
RAD21_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
GSE115542_5_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-O5YW-0426-SM-3MJHJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931809
GTEX-WFON-0001-SM-3P61W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00284
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.125
PARP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64509
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.34061
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WM-266-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.897
ARG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7088
RPEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97241
UBXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63879
KDM3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19628
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-A5NK-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE176008_0_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BICR 31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.840115
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.835608
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.0536
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00568
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.69724
GTEX-QCQG-1326-SM-48U24	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83962
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.53752
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7177-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-A5G3-01A-31R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.840952
NCIH1435	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41544
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
647-V	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DKMG	CCLE Cell Line Gene Expression Profiles	1.0	1.64596
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25682
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.08303
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P7-A5NY-05A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-DX-AB2F-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chemical synaptic transmission	GO Biological Process Annotations 2025	1.0	null
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03098
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.922435
CORL47	DepMap CRISPR Gene Dependency	1.0	6.36497
inner portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14319
gonad	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.7799
ZNF84	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46727
H-NS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.031
SRC	Pathway Commons Protein-Protein Interactions	1.0	null
RCCFG2	DepMap CRISPR Gene Dependency	1.0	2.59061
MED28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69324
ZNF671	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42833
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6771
SNU489	CCLE Cell Line Gene Expression Profiles	1.0	1.73347
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14518
GTEX-S32W-1226-SM-4AD67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01128
CRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6155
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
ITCH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42677
GTEX-XMD1-0011-R6A-SM-4AT5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01299
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-7332-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
efo21	HPA Cell Line Gene Expression Profiles	1.0	1.12214
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19982
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.867403
SU-DHL-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.887538
CTCF_MCF-7_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LZTS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18488
PIGU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48871
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.907571
hsa-miR-548aa	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
CTCF_MEL cell line_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2435
NOZ	DepMap CRISPR Gene Dependency	1.0	2.13623
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
facial motor nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1359
GTF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90221
CTCF_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV6-01A-21R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
GTEX-NPJ8-1426-SM-3MJHR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17028
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06342
PDGFRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81725
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MY-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
NENF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4804
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A5W9-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRAPPC2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3076
molecular_function	GO Molecular Function Annotations 2015	1.0	null
GTEX-QVJO-0011-R5A-SM-2S1QM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971924
MAFK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03955
peripheral portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.906911
WNK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26365
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8630-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.30916
Duodenum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.157
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3912
PTPN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56533
CTCF_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNOS-0326-SM-4DM6C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0299
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.920941
ETV4_01_356	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.71495
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888445
RAB22A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07979
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4545
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.961336
hsa-miR-3187-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Peripheral nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.121
GTEX-PLZ5-0426-SM-3P612	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829355
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
GTEX-XMK1-0001-SM-4B64F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
RC-K8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.85184
GTEX-WRHU-0006-SM-3MJF6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.950995
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNF4A	JASPAR Predicted Transcription Factor Targets	1.0	null
cell communication	GO Biological Process Annotations 2015	1.0	null
GTEX-NPJ7-0011-R6a-SM-2I3G7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48113
Perturb_16513_KD_C11orf53_SRP343255	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.5687
H2AZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71811
SC-8002 (ESR1)	NURSA Protein Complexes	1.0	null
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.17304
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6221-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23972
facial motor nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11422
GSE98898_8_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MYCN	ChEA Transcription Factor Targets	1.0	null
Lateral entorhinal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.52
NEPRO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1491
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2672
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.883191
BEND5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51535
Cornelia de Lange syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.873
HUP-T3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.19137
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-06A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vas efferens	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.673321
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Roberts syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.307
ZNF276	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92773
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MBLAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11172
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5676-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
smoothmuscle_8b	HPA Tissue Sample Gene Expression Profiles	1.0	1.06251
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.2366
hsa-miR-548c-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.541
CTCF_A549_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12872_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LOU-NH91	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.919033
KARPAS-299	COSMIC Cell Line Gene Mutation Profiles	1.0	null
blood	GTEx Tissue Gene Expression Profiles	-1.0	-2.10018
SPAG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12001
GSE216273,GSE216292_14_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CA2 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.909087
HRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93944
PMC3708595-NIHMS474972-supplement-1.pdf-8-MYB_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
CDC25A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3536
SNU213	DepMap CRISPR Gene Dependency	1.0	2.2316
OVK-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16937
hsa-miR-548b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
MYOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73494
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
hsa-miR-548j	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
NCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85145
PFKL_OE_GDS4410_75_human_Biceps muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.40741
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MARCHF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91765
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.51249
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9563
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.910654
GSE205163,GSE205164_9_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
IRF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8792
Lung adenocarcinoma_LUAD_TCGA-55-6970-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO741	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63759
DOR 13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.31701
SSTR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53084
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8336-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.71023
DUT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52515
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.909049
SNU1272	CCLE Cell Line Gene CNV Profiles	1.0	1.38787
CAL-62	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4427-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TADA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14655
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
TDGF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6776
GCT	CCLE Cell Line Gene CNV Profiles	1.0	1.69343
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A9DC-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
breast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074852
H3K9me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
MED30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46039
ERG	ChEA Transcription Factor Targets	1.0	null
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_AA_NP-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
COLO 678	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.881106
PTPRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45267
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.916058
Lung squamous cell carcinoma_LUSC_TCGA-85-A4CL-01A-41R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EXOSC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18961
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840336
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
hsa-miR-548ak	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.197
TBC1D22B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76893
CTCF_fibroblast of mammary gland_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular process	GO Biological Process Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6989-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LT-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KANK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48995
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RU72-3126-SM-46MUB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81898
CTCF_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ccnd1_18413728_imr_neuroblastoma_lof_human_gpl570_gse8866	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.139631
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A66S-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
GTEX-X4EP-3226-SM-3P5YR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36045
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NC-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PKDCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03562
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39155
hippocampus (hippocampal formation)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.850666
GSE205163,GSE205164_2_v_0_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5739
MED16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78791
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE161864,GSE161866_1_v_3_ror2_human	RummaGEO Gene Perturbation Signatures	1.0	null
16715129-SuppTable4	GeneSigDB Published Gene Signatures	1.0	null
GTEX-UPK5-1526-SM-4JBJA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04281
male reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.077668
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888711
hsa-miR-4775	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
496100326_TCx_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1929
POU3F2	ChEA Transcription Factor Targets	1.0	null
ERBB4	Pathway Commons Protein-Protein Interactions	1.0	null
GSE162892_4_v_2_sox9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF383	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74839
NCI-H1793	COSMIC Cell Line Gene Mutation Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.54055
SH3BGRL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52884
Retinal cone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.751
NCI-H2126	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.71176
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5261-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC25A51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92592
CTCF_cardiac fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Buccal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.144
VASN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60564
MDAMB415	CCLE Cell Line Gene CNV Profiles	1.0	1.41285
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.897305
MGMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00767
RT4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
19621087-Table1e	GeneSigDB Published Gene Signatures	1.0	null
NCI-H2135	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PSDG-0008-SM-48TE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.833587
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CELF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35214
Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9D2-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23516
GTEX-RWS6-0526-SM-4GIAJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11933
A-CA-04-2009(H1N1)_18Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.89912
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26488
PPIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29342
MALME3M	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76164
POLR3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7805
CTCF_fibroblast of pedal digit skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01386
YEATS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78897
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01288
GSE151083_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19L-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828195
GTEX-NPJ8-0011-R10A-SM-2YUMO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932271
GTEX-NPJ7-1326-SM-3MJHO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18833
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-8500-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE235066_4_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1077
CNOT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70434
gata3_21892208_mda_mb_231_gof_human_gpl570_gds4080	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.149133
PMC11390959-41598_2024_70075_MOESM3_ESM.xlsx-520_DMD_common_down_gene_list-HES4_HES4	Rummagene Transcription Factor Associations 2026	1.0	null