association	dataset	threshold value	standardized value
IgA glomerulonephritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.164
Autosomal dominant disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.061
Catalytic step 1 spliceosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.957
PMC11426526-ppat.1012555.s011.xlsx-DEG_MDDC_Jurkat_LPS_vs_MDDC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE147943_0_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MA-06-DJ95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.236597
Bone disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.23
PECAPJ15	DepMap CRISPR Gene Dependency	1.0	2.18601
HD-51-KD29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.561014
PMC10290283-biol-2022-0622-sm3.pdf-376-SCMH1_SCMH1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Change_in_both_CSDE1_KD_hESCs-gene_short_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158834_12_v_9_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216273,GSE216292_0_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE192689_0_v_1_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE206729_5_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
UBE2V2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65194
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Change_in_both_CSDE1_KD_hESCs-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Change_in_both_CSDE1_KD_hESCs-hgnc_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CBLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27626
rt1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.261
PMC8384902-mmc5.xlsx-H2107_PROX1_ChIP-Symbol_PROX1	Rummagene Transcription Factor Associations 2026	1.0	null
HARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64322
GTEx Breast 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	-1.0	-3.14202
GSE103068_5_v_1_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Comedo carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.105
GSE217071_1_v_2_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE159893_2_v_1_genistein_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE242083,GSE242098_3_v_0_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PD-70-VS77_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.502048
IA-27-CK10_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.317797
GSE141624_3_v_6_cocaine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE176555,GSE176556_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Thymic cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.576
F5	DepMap CRISPR Gene Dependency	1.0	2.11402
FB-66-UU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.259303
Estimated glomerular filtration rate	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.9699
CTCF-33576154-HUMAN-HILARLN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
Mean arterial pressure x alcohol consumption (light vs heavy) interaction (2df test)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.05229
6862_PSMC5_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.575415
PMC7293310-41467_2020_16179_MOESM8_ESM.xlsx-Table_S9_GATA1_WT24h_vs_SET24-Unnamed_10_GATA1	Rummagene Transcription Factor Associations 2026	1.0	null
NPEPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03061
GSE217776,GSE217829_2_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Glaucoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.756
TYSND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15683
Hindbrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE163282_12_v_8_aspirin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE207135_2_v_0_sod2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8384902-mmc6.xlsx-DEG_ASCL1_3TF_shared-GeneSymbol_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
Abdominal obesity-metabolic syndrome	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.061
RPS20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51368
CTCF-33576154-HUMAN-LIVER-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
8666_TAF5_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.681827
GSE186647,GSE217287_1_v_3_hnrnpc_human	RummaGEO Gene Perturbation Signatures	1.0	null
CE-00-EK89_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.349815
PMC5352183-oncotarget-08-624-s009.xlsx-Table_S20-1_indicates_that_the_gene_is_both_a_TP53-MW_and_a_TP53-MSN_gene_in_the_correponding_cancer_and_0_indicates_not_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GSE242555_1_v_0_fn3k_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VD-88-MW70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.38089
Heart disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.852
SLC48A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14044
GSE247230_0_v_1_anp32b_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8384902-mmc7.xlsx-105_ASCL1_Direct_repressed-Unnamed_1_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.3202
GSE228430_2_v_3_fabp5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE42805,GSE42811_2_v_3_cocaine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10120965-pwac038_suppl_supplementary_table_s4.xlsx-siFOXP1-2_vs_siNC-Differentially_Expressed_Genes_DEGs_in_hCMs_upon_Silence_of_FOXP1_FOXP1	Rummagene Transcription Factor Associations 2026	1.0	null
DC-51-WE27_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.240384
GSE202434,GSE202438_2_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE215086_0_v_2_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE234043_0_v_1_abcb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
XC-81-LR46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.252821
Monogenic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.061
GSE226285_3_v_1_nr0b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.41758
PMC11665559-jciinsight-9-183889-s131.xlsx-Fig2DiffBind_MYB_TR-PLEvsNTC-WT-Gene_Name_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
DC-84-CJ21_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.48719
GSE144796_3_v_0_linagliptin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-1n_h-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
MAD2L1BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0312
GSE165939_2_v_1_poldip2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GE-22-ME44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.20216
GSE186707_1_v_0_hdac4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE121198,GSE129779_3_v_1_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DC-93-RZ62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.330418
PMC11665559-jciinsight-9-183889-s131.xlsx-Fig2DiffBind_MYB_TR-PLEvsNTC-WT-Nearest_Ensembl_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
DDX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5935
GSE113221,GSE113968_6_v_1_prdm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158632_2_v_5_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2697
GSE135030_8_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE198380_0_v_1_phgdh_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146982_4_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE87412,GSE92423_0_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LARP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06101
HT1376	DepMap CRISPR Gene Dependency	1.0	2.30998
Prdm15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.8476
SLC25A51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92592
GSE171175,GSE171181_1_v_0_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE188458_2_v_4_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CCDC78	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05394
OE-31-YC41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.293189
GSE102675_3_v_0_atf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Whole Blood	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.17015
GSE153124_4_v_3_dsg2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PACADD119	DepMap CRISPR Gene Dependency	1.0	2.17868
GSE151412_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MRPL57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85427
GSE249544,GSE249637_6_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_12_v_4_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MMACHC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59035
496100305_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.01754
KA-29-AB08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.390036
GSE224877_3_v_0_pctp_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Increased_in_both_CSDE1_KD_hESC-gene_short_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE258991_5_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE135030_8_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GINS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05814
496100485_PCx_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.58773
RUNX1-22343733-PBMC-HUMAN-BONEMARROW	ChEA Transcription Factor Targets 2022	1.0	null
ZNF555	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07607
GSE199644_3_v_2_palmitic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE203485_1_v_0_zdhhc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE76425_0_v_3_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE151829,GSE151831_3_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Major depressive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.559
AF-99-HA02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.325142
Acne (severe)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.05229
PMC12513837-41588_2025_2336_MOESM4_ESM.xlsx-Supplementary_Table_1-Supplementary_Table_1_List_of_AR-only_and_p300_AR-shared_enhancer_regulated_genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE182680,GSE182683_5_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100338_HIP_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.24931
ETV6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4379
FOXA1-33576154-HUMAN-LIVER-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
GSE171837_0_v_3_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE121824,GSE121826_0_v_7_scaf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE198036,GSE198041_4_v_3_sox9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_12_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9362915-pone.0272017.s003.xlsx-Day5_-0_7_Top-BBX_BBX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE79663_2_v_0_tcf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210885_5_v_7_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TA-34-CK62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.371334
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2971
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.216127
GSE134375_3_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GE-47-OO30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.28977
PMC9013128-NIHMS1795992-supplement-4.xlsx-501mel_ARID2_KO_Downregulated-Gene__name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210505_0_v_1_sox1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RINL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06094
PMPCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1083
GSE115363_1_v_5_esrrb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AA-30-BE85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.251573
8897_THTPA_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.558017
SYNM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5503
GSE146612_2_v_3_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE206226_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ANKRD13C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3645
BT16	DepMap CRISPR Gene Dependency	1.0	2.36479
GSE261563_3_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CDH4-35650610-MESC-MOUSE-STEM-AUTISM	ChEA Transcription Factor Targets 2022	1.0	null
FA-63-WI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.90973
GSE195503_3_v_2_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TCEAL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45087
GSE221327_8_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
7091_RANBP10_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.520106
NP5	DepMap CRISPR Gene Dependency	1.0	2.31147
BB-86-BE19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.202514
GE-53-SM76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.204312
GSE202434,GSE202438_4_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE139966_4_v_0_figla_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MRPL55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61702
CDC14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.602
GSE103124_1_v_0_bmpr1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Increased_in_both_CSDE1_KD_hESC-hgnc_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
JOPACA1	DepMap CRISPR Gene Dependency	1.0	2.05751
Rheumatoid arthritis disease specific synovial fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.064
ZNF770	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.7141
GSE166783_3_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RBMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12053
NCIH1568_LUNG	CCLE Cell Line Proteomics	1.0	5.09565
Mean platelet volume	GWAS Catalog SNP-Phenotype Associations 2025	1.0	3.9
PMC8901773-41598_2022_7986_MOESM3_ESM.xls-PIO_vs_LPS-Gene_symbol_ENSEMBL_ID_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE200430_1_v_0_sema3d_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TA-34-CK62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.341157
GSE103122_0_v_1_riok3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
7753_SEC61G_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.511392
ZBTB11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5244
GSE166783_1_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Hippocampus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE218949_0_v_1_cep20_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE70499_3_v_1_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MH7A cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.999
ANAPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20458
PMC11951866-mmc1.pdf-5-MLXIP_MLXIP	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158834_12_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9181267-mmc5.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
GSE233679_6_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4521181-oncsis201520x8.pdf-67-ZNF80_ZNF80	Rummagene Transcription Factor Associations 2026	1.0	null
DUSP22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79056
MERO82	DepMap CRISPR Gene Dependency	1.0	2.31546
1197_CARS_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.531625
Thymus gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.018
GSE112761,GSE112767_2_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
C2CD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00389
GSE166920_6_v_8_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE150072,GSE169209_6_v_11_qser1_human	RummaGEO Gene Perturbation Signatures	1.0	null
KA-75-LP02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.367934
GSE202434,GSE202438_7_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.4167
PMC11655728-12672_2024_1562_MOESM2_ESM.xlsx-Sheet1-Hs_ESC_SOX2_targets_Boyer_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE200839,GSE233826_5_v_0_tnrc18_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lymph node	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.052
GSE171175,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE226316_6_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE228413_2_v_5_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.852
PMC6080909-JEM_20171312_TableS1.xlsx-miR-196_predicted-Table_S1_miR-196a_b_predicted_targets_by_PITA_PicTar_TargetScan_and_DIANA_prediction_algorithms_ZFP1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE215849_2_v_1_muc1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EL-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.845
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.73294
Microtubule bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.61
PMC12586162-41593_2025_2050_MOESM3_ESM.xlsx-Supplementary_Table_7-ELK1_unique_ELK1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11437185-41467_2024_50986_MOESM4_ESM.xlsx-HDSP-KD-RNAseq-Gene_Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE190186,GSE190188_8_v_10_apoe_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE226249_5_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.500928
Pparg::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.8684
GSE121824,GSE121826_0_v_2_scaf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE195503_1_v_2_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AF-99-HA02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.207412
GSE216394_2_v_0_pfkp_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE77108_0_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DD-75-HY40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.349916
PMC8755441-mmc3.xlsx-IRF3-Up-IRF3-Hela_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE247862,GSE247863_0_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8387919-mmc2.xlsx-ST2_NEUROG3_binding_sites-Unnamed_13_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
496100478_HIP_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.80033
NCIH2882	DepMap CRISPR Gene Dependency	1.0	2.13982
GSE202434,GSE202438_8_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7406
PMC10836071-media-2.xlsx-Supplementary_Table_5-ELK1_all_ELK1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE60837_2_v_4_bcl9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9104818__F5	PFOCR Pathway Figure Associations 2024	1.0	null
GSE131660_2_v_0_piperlongumine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE154940_1_v_0_nbdy_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Gastroesophageal cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FF-86-NH56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.67229
MFE319_ENDOMETRIUM	CCLE Cell Line Proteomics	1.0	3.01235
TECR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74387
GSE195559_6_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Mean arterial pressure x alcohol consumption interaction (2df test)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.809691
PMC8452624-41467_2021_25709_MOESM12_ESM.xlsx-ST12-Unnamed_2_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Diastolic blood pressure x alcohol consumption interaction (2df test)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.5699
7141_RBBP5_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.503249
ETV7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6933
PR interval	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.739794
PMC12623973-41467_2025_64981_MOESM3_ESM.xlsx-downregulated-c0_ACKR4_SCS_ceiling_LEC_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE200352_10_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE60367_2_v_1_cxcr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE82110,GSE82299_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Connective tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.23
OF-05-CB18_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.448122
MCC13	DepMap CRISPR Gene Dependency	1.0	2.05161
MAGED4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03218
IE-49-AI35_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.342068
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8393
KA-29-AB08_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.258827
GSE221327_10_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE108500_1_v_0_foxp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5452392-13058_2017_854_MOESM3_ESM.xlsx-Table_S7-Variants_within_GWAS_blocks_control_MAF_0_01_case_MAF_control_MAF_within_gwas_breast_cancer_regions_deleteious_score_0_5_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
Cytosol	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.895
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_Jurkat_LPS_vs_DC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CEBPE	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9807
PMC8566473-41467_2021_26653_MOESM3_ESM.xlsx-SOX2_interacting_proteins-Gene_symbol_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE139966_5_v_3_figla_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBED1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7345
GSE202434,GSE202438_3_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE166920_6_v_2_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF140	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.0804
GSE133213_6_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE242290_1_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Abdominal obesity-metabolic syndrome 1	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.061
ECC4	DepMap CRISPR Gene Dependency	1.0	2.04283
GSE185944_2_v_4_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Tranilast_PANC-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00204209
HTRA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60412
GSE112760,GSE112767_1_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH522_LUNG	CCLE Cell Line Proteomics	1.0	3.37945
YD-49-HM53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.216585
OCUG1	DepMap CRISPR Gene Dependency	1.0	2.02556
GSE111035,GSE111040_8_v_5_plag1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GIMEN	DepMap CRISPR Gene Dependency	1.0	2.00006
ELK4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5851
Arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.23
FU97	DepMap CRISPR Gene Dependency	1.0	2.02517
GSE168797_2_v_0_cannabidiol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE137914_4_v_3_tet3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6268
GSE151782_1_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SBC5_LUNG	CCLE Cell Line Proteomics	1.0	2.02889
GSE223287,GSE223290_2_v_4_braf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Alectinib	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.65
EGLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99788
GSE200839,GSE233826_2_v_0_tnrc18_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135350_3_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6347712-pnas.1812449116.sd04.xlsx-Differential_IRF7_to_GFP-ID_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
GNL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29942
GSE200673,GSE200691_2_v_0_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POGK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28148
GSE196671_6_v_1_obox4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12224833-12967_2025_6787_MOESM3_ESM.xlsx-DEGs_PDX1-GeneSymbol_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
SNU182	DepMap CRISPR Gene Dependency	1.0	2.26253
EIF4G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02845
GSE196671_6_v_8_obox4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193258,GSE193259_5_v_1_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CAKI2_KIDNEY	CCLE Cell Line Proteomics	1.0	2.72531
GSE62843,GSE64371_4_v_3_furan_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
496100611_FWM_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10631
SB-28-EJ14_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.212818
ZNF236	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00412
M140325	DepMap CRISPR Gene Dependency	1.0	2.25989
GSE195503_3_v_0_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RL_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	2.36874
QE-18-WG07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.29236
CPNE9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60217
GSE185944_0_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZSCAN29	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6263
GSE135030_8_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
STAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25365
IFT140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.681
GSE128333_3_v_0_tcf4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
C17orf49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07091
BA-69-TQ80_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.248846
Liver	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.17053
IC-05-AW29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.284239
GSE240027,GSE240030_1_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0583
GSE224877_2_v_1_pctp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PC-68-DU31_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.299523
EE-32-EY37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.254941
GSE111385_0_v_1_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CNTROB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17057
COX6A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01997
Proventriculus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.652
GSE155695,GSE155696_1_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SOX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11495
CA-75-HA22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.258445
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_4_Overlap_of_ERM_proteom-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
Waist-to-hip ratio adjusted for BMI (additive genetic model)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.752288
SLC25A22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15221
ANAPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11679
PMC10537816-12967_2023_4509_MOESM1_ESM.xlsx-ST12-Unnamed_4_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE216273,GSE216292_14_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.256356
GSE135030_8_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00914
ABCB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02265
GFM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07073
Minor Salivary Gland	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.46383
GSE138945,GSE138947_0_v_1_mboat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PAX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1818
PMC10746608-427_2023_709_MOESM5_ESM.xlsx-SOX2_partners-SOX2_known_protein_partners_according_to_BioGrid_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
Cerebral lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PMC12515692-MOL2-19-2882-s001.xlsx-Phosphoproteome_AKT2_KD_vs_SCR-Unnamed_3_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Eplerenone_J82	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00520191
Systemic lupus erythematosus	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.51549
PMC8384902-mmc5.xlsx-H128_PROX1_ChIP-Symbol_PROX1	Rummagene Transcription Factor Associations 2026	1.0	null
Large cell neuroendocrine carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.515
UMUC9	DepMap CRISPR Gene Dependency	1.0	2.18946
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.746034
GSE228181_0_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.892
Spz1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.8333
SKUT1	DepMap CRISPR Gene Dependency	1.0	2.34129
Brain - Spinal cord (cervical c-1)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.35455
SUCLG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65753
4116_INCENP_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.5781
PMC4856960-supp_gkv1471_nar-01762-z-2015-File012.xlsx-GO_common_7H-HIF1_chip-Common_elements_in_chip7h_and_chip_hif1_2530_official_gene_symbols_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
AB-71-CI37_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.320197
GSE202434,GSE202438_6_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PECAPJ34CLONEC12	DepMap CRISPR Gene Dependency	1.0	2.10099
GSE139966_1_v_2_figla_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mBAF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.49
PMC8995879-Table_1.xlsx-exome_variants_MAF_0_01-Gencode_34_hugoSymbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE180185_7_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HES2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5484
MAPK1IP1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20334
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Increased_in_both_CSDE1_KD_hESC-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HOOK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07295
GSE233679_5_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE235945_1_v_0_pikfyve_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CACNB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03964
POLE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31819
GSE166783_8_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.37655
Pituitary	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.34178
GSE242199_6_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE242290_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AURKA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12441
GSE216273,GSE216292_0_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Eye disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.756
Bone marrow cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE231648_1_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE144443_0_v_6_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE147056_0_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BAG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00878
TIMELESS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45189
GSE144231_4_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE235701,GSE261434_2_v_1_enasidenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RA-49-ZB08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.375025
GSE142684_4_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ELK1::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5668
Brain stem	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
AB-71-CI37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.385527
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF_D1_vs_D10-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
CARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33147
Genetic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.061
CFAP97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33303
GSE137914_0_v_3_tet3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Thymus cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
GSE135400_1_v_0_kdm1b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
IKBKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09883
GSE226285_3_v_1_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
Tfcp2l1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	52.2428
GSE242333_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202434,GSE202438_15_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BB-87-SF89_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.252407
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.081
TIMMDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79672
KB-05-VJ83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.273744
GSE158834_2_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Precatalytic spliceosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.984
2022_DAGLB_ENST00000297056.6	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.565544
GSE139966_4_v_3_figla_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.52223
ZNF418	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43671
GSE58724_3_v_4_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ND-39-PO34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214576
PD-14-WO27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.271344
CD-20-MH57_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.526467
ZNF77	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23578
POU2F1-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE213588_9_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HNRNPAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92616
GSE203308_14_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BE-29-HA72_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.278581
GSE189356_5_v_6_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Dexrazoxane	DeepCoverMOA Drug Mechanisms of Action	1.0	0.24
GSE158100,GSE158101_1_v_0_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158834_12_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4856960-supp_gkv1471_nar-01762-z-2015-File010.xls-Genes_5kb_E2F7_Hyp-gene_name_E2F7	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11655728-12672_2024_1562_MOESM2_ESM.xlsx-Sheet1-Hs_ESC_NANOG_targets_Boyer_NANOG	Rummagene Transcription Factor Associations 2026	1.0	null
SNU1544	DepMap CRISPR Gene Dependency	1.0	2.13108
GSE138019_4_v_5_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEx Skin 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	-1.0	-5.82874
GSE137144_3_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE188382_4_v_0_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_17_KD_HEK293-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE160017,GSE160022_1_v_0_trem2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157383_6_v_2_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE103122_0_v_1_puromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
YD-49-HM53_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.214257
GSE133516_5_v_6_kat7_human	RummaGEO Gene Perturbation Signatures	1.0	null
ARPP19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17811
PMC10120406-JEM_20220962_DataS2.xlsx-Elf1_target-Data_S2_List_of_Elf1-target_genes_2_d_after_LPS_pIpC_stimulation_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_A549_KD-GeneID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NUBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71449
Diastolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.0
PMC9362915-pone.0272017.s004.xlsx-Day5_-0_7_Top-BBX_BBX	Rummagene Transcription Factor Associations 2026	1.0	null
JE-72-KV75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.219343
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1627
GSE193258,GSE193259_5_v_8_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
colo829	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.887
GSE196540,GSE196542_2_v_5_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8755441-mmc3.xlsx-IRF3-Up-IRF3-encode-consensu_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE247862,GSE247863_2_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135030_8_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MB-46-BT89_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.240957
Placental membrane	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.932
Erythroleukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE185944_0_v_3_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE185944_5_v_3_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23823
PIP5KL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59196
GSE112763,GSE112767_4_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AB-33-EM56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.23788
KDM5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41482
FB-66-UU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.256846
PMC9181267-mmc5.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
GB-57-XV52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.400261
GSE134615_1_v_0_lats1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MRPL46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02235
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5656
GSE60837_6_v_4_bcl9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9181267-mmc5.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
GSE243199_1_v_0_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
OLIG2-29049317-MOUSE-SPINALCORD	ChEA Transcription Factor Targets 2022	1.0	null
DETROIT562	DepMap CRISPR Gene Dependency	1.0	2.12096
Thymoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.043
HC-01-FD24_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.532127
MDFI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09882
CNIH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4086
Integumentary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.892
FE-64-KC49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.290173
GSE139455_4_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE140607_3_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9452874-40246_2022_406_MOESM3_ESM.xlsx-ARM_HT_ST18_Replicate_Evangelou-Supplementary_Material_X_Summary_statistics_for_known_HT_GWS_signals_in_our_dataset_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
POMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43479
GSE167956_4_v_0_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
SNU216	DepMap CRISPR Gene Dependency	1.0	2.03005
GSE192771_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MLH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24992
Sensory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.756
Bone inflammation disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.23
GSE151782_6_v_5_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE60217_1_v_10_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE233679_6_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H838 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.212
GSE244072_10_v_9_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE242290_1_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202310_1_v_0_ube3d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4634137-ncomms9549-s7.xlsx-ZF_Hair_cell_data-Unnamed_1_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
SNX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15007
PAX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1296
GSE149035_3_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE236504,GSE236505_0_v_1_atmin_human	RummaGEO Gene Perturbation Signatures	1.0	null
MC-40-IP75_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202405
Thymidine	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.26
EDF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20982
GSE245270_1_v_5_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE142210_2_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
HKA1	DepMap CRISPR Gene Dependency	1.0	2.30018
NFKB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6068
SOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40128
GSE228181_2_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE127790_10_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BB-93-VT73_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.55504
GSE168918_1_v_0_tmprss4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142588_2_v_1_cinobufagin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney - Cortex	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.43078
GSE137144_2_v_0_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9941047-41591_2022_2163_MOESM3_ESM.xlsx-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE198165,GSE198166_7_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EA-18-FP00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.229212
Oligodendrocyte_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
GSE231648_4_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE242290_1_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF-31629814-HEPATOCYTES-MOUSE-TYROSINEMIA	ChEA Transcription Factor Targets 2022	1.0	null
PMC10153265-media-3.xlsx-BENPORATH_SOX2_TARGETS_v2023_1-STANDARD_NAME_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6855629-pone.0225186.s009.xlsx-Sheet1-DEGs_downregulated_in_HEK293_MEIS1_KO_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
ACTR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60119
GSE213588_10_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NRSN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49479
BD-49-MD69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.294954
PMC8387919-mmc2.xlsx-ST2_NEUROG3_binding_sites-Unnamed_12_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12019345-41598_2025_98989_MOESM10_ESM.xlsx-Sheet_1-CCNE2_related_genes_AND_HNSCC_HNSCC_DDP_NOT_DDR_Genes_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE195503_1_v_0_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE74251_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11031761-mmc2.pdf-3-ZFPM2_ZFPM2	Rummagene Transcription Factor Associations 2026	1.0	null
Coronary artery disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.769897
SP2509	DeepCoverMOA Drug Mechanisms of Action	-1.0	-1.31
GSE137144_2_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
UNK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91068
KIAA1522	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50574
GSE121824,GSE121826_0_v_6_scaf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MON	DepMap CRISPR Gene Dependency	1.0	2.3927
ZNF177	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46399
GSE248858_1_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10061014-Table5.XLSX-C_vs_LD-Table_S5c_Results_of_gene-wise_analysis_of_cd-ASE_depending_on_LPS_DEX_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
KA-29-AB08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.372564
GSE127790_9_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149903_5_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.484267
AS-605240	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.29
GSE150669_0_v_3_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
2291_DNAJC17_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.572832
GSE152055_0_v_1_mpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NE-94-VE83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.256065
DPPA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07012
ND-54-NO97_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204064
Syndromic microphthalmia 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.095
6868_PSMD14_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.637636
GSE125219,GSE125221_4_v_8_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DB-54-GQ68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.272887
GSE213588_10_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE95826_4_v_1_tcra_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE235701,GSE261434_0_v_1_enasidenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DIS3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27375
GSE228181_3_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Zfx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.7473
FF-22-NB12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.224358
S0-EE-YNU4_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202242
PMC9314667-Table_1.xlsx-Regulons-HES6_HES6	Rummagene Transcription Factor Associations 2026	1.0	null
496100359_PCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.23817
PMC9336541-Table_3.XLSX-C-vs-H6-L_filter_annot-Unnamed_18_HMX1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7645
MAPACHS77	DepMap CRISPR Gene Dependency	1.0	2.10705
GSE218960_0_v_1_nrf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE227891_5_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE201309_5_v_8_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE87404,GSE87812_1_v_0_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09227
JD-81-YX02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.278345
GSE112995,GSE132079_1_v_3_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE206502_2_v_1_igf2bp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE227592_6_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RRN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.88206
GSE166536_1_v_2_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10153265-media-3.xlsx-BENPORATH_NANOG_TARGETS_v2023_1-STANDARD_NAME_NANOG	Rummagene Transcription Factor Associations 2026	1.0	null
KCNE5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28613
GSE186660_2_v_1_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10061014-Table5.XLSX-C_vs_L-Table_S5a_Results_of_gene-wise_analysis_of_cd-ASE_depending_on_LPS_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE93674_2_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158834_1_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE114883_0_v_5_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE60691_0_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE205730,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAVER1	DepMap CRISPR Gene Dependency	1.0	2.15099
NXT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20566
SMPDL3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1366
2236_DLAT_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.505892
a-Naphthoflavone	DeepCoverMOA Drug Mechanisms of Action	1.0	0.25
GSE189941_1_v_2_kdm4c_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE209582_1_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE166920_6_v_5_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11385326-joces-137-261952-TableS5.xlsx-AP2_possible_cargo-Gene_names_AP2_GTF3A	Rummagene Transcription Factor Associations 2026	1.0	null
Rheumatoid arthritis disease specific synovial tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.827
GSE131798,GSE131804_2_v_0_igf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CD-05-PU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.349847
GSE151782_2_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WE-48-PP43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.308352
MGME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67411
GSE203308_14_v_0_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216273,GSE216292_0_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H-1152	DeepCoverMOA Drug Mechanisms of Action	1.0	0.26
GSE121198,GSE129782_1_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9084694-RMB2-21-e12464-s005.xlsx-GV_MI_MII_GV-up-GeneName_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE212760_0_v_1_fxr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE185944_2_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.892
GSE95685_2_v_5_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ACD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41921
Metencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Nrf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	69.8686
GSE169571_3_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.36106
GSE112763,GSE112767_0_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE203060_0_v_2_kdm4c_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.422644
GSE202434,GSE202438_7_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11373733-ABR-13-34_Suppl1.pdf-177-SETDB1_SETDB1	Rummagene Transcription Factor Associations 2026	1.0	null
MBIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17156
JURKAT	DepMap CRISPR Gene Dependency	1.0	2.45184
CHORDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73198
PMC7181646-41523_2020_157_MOESM4_ESM.xlsx-RNAseq_KD_vs_Control_DEG-Gene_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE77178_5_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE112761,GSE112767_2_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.329408
KMT2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4476
Brain - Frontal Cortex (BA9)	GTEx Tissue Gene Expression Profiles 2023	1.0	2.24503
BD-49-MD69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.228964
RPS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14787
GSE184892_7_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE212848_1_v_0_pum1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
U5 snRNP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.271
NCIH28	DepMap CRISPR Gene Dependency	1.0	2.19418
WASHC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14911
FNBP1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05766
Dichlorisone	DeepCoverMOA Drug Mechanisms of Action	1.0	0.23
GSE205730,GSE205731_2_v_0_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE95685_6_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ELF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.296
GSE139966_4_v_2_figla_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GC-04-UF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.494308
GSE165274_1_v_2_poldip2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MRPL44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53121
GSE151782_1_v_5_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE140607_5_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE196505,GSE196507_3_v_2_kdm2b_human	RummaGEO Gene Perturbation Signatures	1.0	null
KF-18-RY71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.241362
Serum uric acid levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.669897
GSE110524_2_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CCDC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07402
Refractive error	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.05229
GSE242333_0_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
9910_XRN1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.581797
GSE242290_3_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE167373_2_v_3_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE245270_1_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE261563_9_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF-_SURVIVAL-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE203329_2_v_1_mettl5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_3_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9181267-mmc5.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7293310-41467_2020_16179_MOESM8_ESM.xlsx-Table_S9_GATA1_WT24h_vs_SET24-Unnamed_12_GATA1	Rummagene Transcription Factor Associations 2026	1.0	null
6581_POT1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.95834
BB-64-EE60_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.553507
GSE151494_8_v_3_nrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148252_1_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7794364-41540_2020_161_MOESM3_ESM.xlsx-NSP_Unique_-_PPH2_predictions-Gene_Sym_SMAD9	Rummagene Transcription Factor Associations 2026	1.0	null
Nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.756
GSE196104,GSE196106_2_v_0_vsx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135030_11_v_1_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PTPN13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23258
2893_TAFA2_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.522291
PMC12515692-MOL2-19-2882-s001.xlsx-Phosphoprot_AKT1_AKT2_KD_vs_SCR-Unnamed_3_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SIRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50976
496100335_PCx_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.09339
DDX42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36378
GSE121198,GSE129779_3_v_2_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DCUN1D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.87542
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.29228
t60-adrenal_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.81901
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_2_TurboID_10m_ERM_proteome-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
SERHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3333
PMC12586162-41593_2025_2050_MOESM3_ESM.xlsx-Supplementary_Table_7-ELK1_all_ELK1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE206516,GSE206518_1_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE125007,GSE125008_10_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE242290_3_v_2_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216273,GSE216292_14_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE147943_2_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE118548_1_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE74251_0_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CAL120	DepMap CRISPR Gene Dependency	1.0	2.21636
GSE190186,GSE190188_0_v_5_apoe_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Osteoarthritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.23
BICR31	DepMap CRISPR Gene Dependency	1.0	2.16928
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
496100631_PCx_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.59032
10623_ZNF774_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.928204
U4/U6 snRNP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.004
PMC3964217-oncotarget-05-417-s001.xls-Supplemental_Table_3-GABPA-bound_promoters_GABPA	Rummagene Transcription Factor Associations 2026	1.0	null
CXXC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34729
5521_NDE1_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.607146
GSE111385_0_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE225141,GSE225143_2_v_3_mettl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KA-75-LP02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.209111
Cervix - Ectocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	1.64491
Cerebellum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE192689_0_v_3_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TOPORS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02563
GSE261563_0_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142588_2_v_0_cinobufagin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AC-28-RT00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.23486
GSE124375_13_v_0_chd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146982_4_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE240027,GSE240030_5_v_2_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE144443_10_v_3_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Common_KLF5_peaks-Nearest_Ensembl_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8384902-mmc7.xlsx-105_ASCL1_Direct_repressed-Unnamed_15_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
DB-21-FY75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.387115
PMC9195629-Table1.xlsx-Supplementary_Table_1-JUN_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7098486-mmc2.xlsx-Kgg_Quant_NGN2_AAVS_-_WCL-Unnamed_2_NEUROG2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE193258,GSE193259_2_v_8_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11096100-41588_2024_1714_MOESM3_ESM.xlsx-ST18-Unnamed_1_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
GSE238018_3_v_5_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
AC-84-QG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.273421
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.32199
UC-00-QA88_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.277692
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_A549_KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE201877_1_v_0_yap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEx Skin 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-12.2474
Thap11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.8561
DA-35-DU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222612
RERFLCAD2	DepMap CRISPR Gene Dependency	1.0	2.3939
GSE127790_4_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE235017_1_v_0_uba52_human	RummaGEO Gene Perturbation Signatures	1.0	null
KA-81-AG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.23149
Nimesulide_PANC-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00705407
KC-48-OO62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205866
AQ-390/43364023	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.23
GSE160373_6_v_2_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JA-02-IU07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.37418
S1PR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17924
PC3	DepMap CRISPR Gene Dependency	1.0	2.13963
GSE222598_1_v_0_sf3b4_human	RummaGEO Gene Perturbation Signatures	1.0	null
6611_PPAT_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.551538
GSE206729_5_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NBTGR	DeepCoverMOA Drug Mechanisms of Action	1.0	0.24
GSE140997_4_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100316_TCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.37842
GSE199921_1_v_0_romidepsin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE161295_2_v_5_cdk8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE247862,GSE247863_0_v_3_eomes_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Syndrome	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.061
PMC10836071-media-2.xlsx-Supplementary_Table_5-ELK1_unique_ELK1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE150895,GSE150896_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12515692-MOL2-19-2882-s001.xlsx-Phosphoproteome_AKT1_KD_vs_SCR-Unnamed_3_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE200673,GSE200691_2_v_3_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100463_FWM_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01455
PC14_LUNG	CCLE Cell Line Proteomics	1.0	3.68288
PMC12585103-pbio.3003444.s013.xlsx-List_of_genes_for_GO_analysis-List_of_genes_undergoing_significant_MXE_upon_PRMT5_KD_under_hypoxia_AR	Rummagene Transcription Factor Associations 2026	1.0	null
DC-70-EK34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.590402
open-angle glaucoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.756
BHT101	DepMap CRISPR Gene Dependency	1.0	2.31465
GSE186287_2_v_3_ufm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Brain - Substantia nigra	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.11908
DLX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34453
Leukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Synovial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.791
GSE148263_6_v_9_trim3_human	RummaGEO Gene Perturbation Signatures	1.0	null
MIA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76034
Erg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.9475
Musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.23
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3136
NCAPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39019
PMC8481886-Table_2.xlsx-A_subsets-common_MSC_AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE60691_2_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TR146	DepMap CRISPR Gene Dependency	1.0	2.17048
VA-92-QP54_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.347334
Prespliceosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.731
FUOV1_OVARY	CCLE Cell Line Proteomics	1.0	2.47968
PMC5358377-pnas.1615015114.sd02.xlsx-Sheet1-genes_with_VDR_peaks_with_and_without_D3_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE84678,GSE93902_1_v_2_bcl11b_human	RummaGEO Gene Perturbation Signatures	1.0	null
Colon adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
BB-74-RX30_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.282286
Small Intestine - Terminal Ileum	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.26404
RVH421_SKIN	CCLE Cell Line Proteomics	1.0	5.88141
TE10	DepMap CRISPR Gene Dependency	1.0	2.12552
GSE213588_10_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-MBNL1_KD_HFE-145-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
POLR1H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01828
GSE60217_1_v_8_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6347712-pnas.1812449116.sd06.xlsx-iPSC_IRF7_48h_rest_RNAExpress-Gene_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
GSE109111_2_v_0_stim1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BA-84-WN26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.33102
HDMYZ	DepMap CRISPR Gene Dependency	1.0	2.00349
GSE226544_1_v_0_hnrnpa2b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE185944_5_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE152441,GSE152442_7_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8684775-CTM2-11-e640-s002.xlsx-Sheet1-Table_S3_MAF_file_of_the_CCS_samples_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC4149371-pone.0105180.s010.xls-NANOG-GENE_NANOG	Rummagene Transcription Factor Associations 2026	1.0	null
GSE249544,GSE249637_6_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DF-00-BU08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.234895
HCC1500_BREAST	CCLE Cell Line Proteomics	1.0	4.43627
Melancholic depression	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.559
GSE122215,GSE122217_5_v_4_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC1419	DepMap CRISPR Gene Dependency	1.0	2.23584
GGPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23852
GSE148262,GSE150691_3_v_2_hdlbp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
interleukin-23 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.599
GSE242290_3_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cervical carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE154069_2_v_4_satb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7181646-41523_2020_157_MOESM4_ESM.xlsx-RNAseq_KD_vs_Control_DEG-GeneName_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BE-79-QU25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.250124
SKBR3	DepMap CRISPR Gene Dependency	1.0	2.05505
GSE196835_0_v_1_ddx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE42805,GSE42811_1_v_0_cocaine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7293310-41467_2020_16179_MOESM8_ESM.xlsx-Table_S9_GATA1_WT24h_vs_SET24-Unnamed_9_GATA1	Rummagene Transcription Factor Associations 2026	1.0	null
EBV-B cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.681
PMC8384902-mmc7.xlsx-105_ASCL1_Direct_repressed-Unnamed_7_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
9680_UTP14A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.551559
GSE248858_1_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Acne	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.892
Ikzf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.1167
GSE190384,GSE190386_3_v_4_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF135	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.4272
S0-EE-YEKU_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.405533
GSE103068_5_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE102870_7_v_0_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_13_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
LYSP100-associated nuclear domain	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.542
Autosomal genetic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.061
JC-95-LT07_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.759004
A2058_SKIN	CCLE Cell Line Proteomics	1.0	4.23626
VMCUB1	DepMap CRISPR Gene Dependency	1.0	2.124
GSE185944_2_v_3_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
S100A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09065
IB-56-JN40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.205616
GSE151412_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Temporal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZNF707	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.7217
PA-75-VL17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.56231
GSE44157,GSE44163_3_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3C11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06691
GSE139239_2_v_6_ddr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
REEP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60361
GSE148252_1_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FEZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.3208
GSE198036,GSE198041_0_v_3_sox9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cognitive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.559
GSE158834_1_v_3_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Common_KLF5_peaks-Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE217156_1_v_3_trpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE200673,GSE200691_2_v_4_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8891017-41586_2022_4394_MOESM4_ESM.xlsx-ST6_-_MAF_enrichment-Unnamed_4_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE226316_1_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8065135-41467_2021_22068_MOESM6_ESM.xlsx-E_MYOG_binding_in_downreg-Unnamed_1_MYOG	Rummagene Transcription Factor Associations 2026	1.0	null
BC-00-YH62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.223952
GSE153443_1_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RPS29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61784
GSE227592_8_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
COPB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59555
GSE103068_0_v_1_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7888619-pgen.1009309.s032.xlsx-S9_Table-S9_Table_Predicted_target_genes_of_POU3F2_POU3F2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
RWDD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15488
GSE249544,GSE249637_6_v_7_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-MBNL1_KD_HFE-145-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HC-01-FD24_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204603
LK2_LUNG	CCLE Cell Line Proteomics	1.0	2.02969
HCC1143	DepMap CRISPR Gene Dependency	1.0	2.13463
GSE173232_1_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AB-09-YX02_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.230796
ZNF783	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20798
GSE211286_1_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TIMM23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74973
MA-58-RR04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.267339
ZBTB12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0862
GSE121824,GSE121826_0_v_8_scaf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PANC0327	DepMap CRISPR Gene Dependency	1.0	2.09651
GSE233049_1_v_3_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE233679_14_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PD-70-VS77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.911849
RSL1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43208
JC-06-ED36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.262187
GSE101767_1_v_0_wdr11_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hand1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.0132
TF-77-DW08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214107
ALDH9A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71204
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Nearest_Ensembl_1_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
ESR1-26153859-T47D-HUMAN-BREAST-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
Synovial sarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.651
GSE188869,GSE188871_1_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Yy1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.8305
GSE205976,GSE205978_2_v_5_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.332871
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4841
Colon - Sigmoid	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.6854
GSE117643_1_v_0_irx5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CDC34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22813
BICR6	DepMap CRISPR Gene Dependency	1.0	2.17677
GSE227698_5_v_0_g0s2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
10875_NON-TARGETING_NON-TARGETING	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.724102
GSE158834_12_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE109140_0_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE185519_3_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE237426_0_v_1_eif4a1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TBCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46634
GSE226584,GSE226589_2_v_0_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Systolic blood pressure x alcohol consumption interaction (2df test)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.0
GSE139966_1_v_0_figla_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HERC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00396
Glutathione hydrolase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.806
5462_NAPA_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.591741
GSE164521_0_v_1_nitric oxide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FAM117A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03812
GSE203017_0_v_1_irs2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Blood cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
6059_TENT2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.538124
Thymoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.594
PRPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89215
BC-62-RZ55_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.236336
ITPR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21396
KYSE450_OESOPHAGUS	CCLE Cell Line Proteomics	1.0	2.39665
GSE207122_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HT1080_SOFT_TISSUE	CCLE Cell Line Proteomics	1.0	3.37945
GSE148252_7_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE203485_1_v_0_sunitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
4959_MED9_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.728479
TPD52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01497
496100628_FWM_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01685
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Gene_Name_1_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
OCIAML5_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	3.68288
IKBKG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10293
QA-50-YO37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.499095
U87MG_CENTRAL_NERVOUS_SYSTEM	CCLE Cell Line Proteomics	1.0	2.73637
Mean arterial pressure	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.03979
DB-21-FY75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.470666
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_17_KD_HEK293-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
EPHA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68818
GSE87404,GSE87812_1_v_3_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE121824,GSE121826_0_v_3_scaf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE224742_0_v_1_slc1a5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE242555_1_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE116810_2_v_4_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
WDR83	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29673
GSE133329_2_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE196104,GSE196106_3_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE168797_2_v_5_cannabidiol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE112763,GSE112767_0_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
M040416	DepMap CRISPR Gene Dependency	1.0	2.06042
Systolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.969897
RBM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02448
GSE240027,GSE240030_1_v_0_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CEBPB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0433
GSE231891_1_v_0_cdk8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE98898_4_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
6889_PSPH_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.639617
NFYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7796
GSE95688_1_v_0_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8758144-elife-74272-supp3.xlsx-AP2_REP2-GeneName_GTF3A	Rummagene Transcription Factor Associations 2026	1.0	null
PMC4823830-ncomms11171-s3.xlsx-high_in_shRNA_GATA3-GeneSymbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
SOWAHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43248
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1609
GSE237040_4_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE139948_3_v_6_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE261563_6_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100538_HIP_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.00109
Anterior pharynx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.543
GSE199204,GSE211619_4_v_3_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_1_BioID_ERM_proteome-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
Depressive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.559
HCC827GR5	DepMap CRISPR Gene Dependency	1.0	2.19371
GSE213588_10_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
EN2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5541
PMC4149371-pone.0105180.s010.xls-SOX2-GENE_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
496100395_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.97736
GSE158438_4_v_12_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Heel bone mineral density	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.55229
GSE128730_0_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE178340_7_v_2_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE137144_4_v_6_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146072_0_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Mood disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.559
GSE217071_3_v_0_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sebaceous gland disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.892
Skin disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.892
BC-10-SB73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.391777
GSE70499_5_v_1_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100380_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.02478
GSE95685_2_v_0_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37856
GSE151090_5_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Natural killer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.862
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.559
PMC8755441-mmc3.xlsx-IRF7-Up-IRF7Del246-647_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
GSE84148,GSE96938_0_v_1_nrros_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE218814_1_v_0_suv39h1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE209601_0_v_1_mef2a_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100324_FWM_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.00424
GSE60837_0_v_3_bcl9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.623
PMC7794364-41540_2020_161_MOESM3_ESM.xlsx-U87MG_Unique_-_PPH2_predictions-Gene_Sym_SMAD9	Rummagene Transcription Factor Associations 2026	1.0	null
Muscle - Skeletal	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.38346
496100319_HIP_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.46273
AB-27-LS15_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.495273
GSE210718_1_v_0_shmt2_human	RummaGEO Gene Perturbation Signatures	1.0	null
NR2F6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75025
BCOR complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.267
GSE203060_0_v_1_kdm4c_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4074
MRPL28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7398