association	dataset	threshold value	standardized value
MYC_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Formic acid	HMDB Metabolites of Enzymes	1.0	null
DNM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18047
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57335
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35434
CRCGN015_MCF10A.TP53.M_24H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.7432
PMC8507136-12935_2021_2224_MOESM5_ESM.xlsx-CREB1_downregulated_RRHO_list-RRHO_concordant_degree_CREB1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QDVJ-0008-SM-48U2E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45231
GTEX-T8EM-0526-SM-4DM64	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996627
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853046
RAD21_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-FX-A2QS-11A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PWOO-0008-SM-48TDU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18266
GTEX-NPJ8-0011-R9a-SM-2YUN5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0106
HCFC1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89871
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6553
CRCGN013_HEPG2_24H:B07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.03651
GSE171837_0_v_2_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NBPF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75641
GTEX-XV7Q-0226-SM-4BRVL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841783
STARD3NL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96181
HINFP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.297
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CBARP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84944
888	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14273
TCF12_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8647
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
ILF3	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QEG5-1426-SM-447AS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09467
IM-95	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ABT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54274
Sarcoma_SARC_TCGA-FX-A48G-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CMTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52999
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.866462
PRKDC	Pathway Commons Protein-Protein Interactions	1.0	null
Peptide deformylase	InterPro Predicted Protein Domain Annotations	1.0	null
HT144SKINFV1	DepMap CRISPR Gene Dependency	1.0	2.75399
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
GTEX-XYKS-1626-SM-4BRUQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992366
CRCGN017_MCF10A.WT.HP_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.27645
PBX3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tRNA-specific adenosine-34 deaminase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.413
hydrolase activity	GO Molecular Function Annotations 2015	1.0	null
SPRED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57364
POLR2A_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE214931_4_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
WC-59-RG09_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.273189
TRAPPC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04592
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC4677459-NIHMS65392-supplement-Dataset3.xlsx-RELA-Unnamed_1_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
ZBTB33_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LSM14A	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN013_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.07945
RBM27	Pathway Commons Protein-Protein Interactions	1.0	null
SIN3A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYBL2	ENCODE Transcription Factor Targets	1.0	null
CRCGN015_HEPG2_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.44536
CRCGN017_MCF10A.WT.HP_24H:M04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.70065
GABPA_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PBX3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RKO-E6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
HCC44	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.01305
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
EIF4H	Pathway Commons Protein-Protein Interactions	1.0	null
H4K5ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBK-0008-SM-3NB27	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11259
PARP1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC7697260__F3	PFOCR Pathway Figure Associations 2023	1.0	null
RAB3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58543
HT55	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.85956
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18957
HCC1162	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01738
USP10	Pathway Commons Protein-Protein Interactions	1.0	null
PACS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48774
Sarcoma_SARC_TCGA-X6-A7W8-01A-21R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PBX3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G118	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.99153
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE165548_2_v_1_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Signal recognition particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.6
RCOR1	ENCODE Transcription Factor Targets	1.0	null
NCDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64315
Breast Cancer_Mammary Gland Tissue_GSE1378	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.386
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.33456
SIRT6	ENCODE Transcription Factor Targets	1.0	null
LN319	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.22808
FE-56-PV35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.989227
GTEX-P4PP-0008-SM-48TDV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6285
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RPL26L1	Pathway Commons Protein-Protein Interactions	1.0	null
peptide deformylase activity	GO Molecular Function Annotations 2015	1.0	null
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
MEL-HO	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.59923
CA-42-YI34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.216472
CRCGN016_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.63143
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5462-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1341	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36363
NXF1	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-5787-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0945
TFPI	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SMSCTR	DepMap CRISPR Gene Dependency	1.0	2.39892
SREK1	Pathway Commons Protein-Protein Interactions	1.0	null
SW620	CCLE Cell Line Gene CNV Profiles	1.0	1.99096
peptidyl-methionine modification	GO Biological Process Annotations 2025	1.0	null
Photosystem	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.24
CRCGN016_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.1559
ELK4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4071
FAM98B	Pathway Commons Protein-Protein Interactions	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
inhibition	GeneRIF Biological Term Annotations	1.0	null
MTFMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06997
GSE203072_2_v_3_rpl3l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.26696
GTEX-XOTO-0826-SM-4B65O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24815
CRCGN015_HEPG2_48H:M17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.84864
THAP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7829
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45Q-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04598
SF3B1	Pathway Commons Protein-Protein Interactions	1.0	null
CDC25B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66565
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.56544
LN18	CCLE Cell Line Gene CNV Profiles	1.0	1.7078
Planktonic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.616
GTEX-VUSG-0008-SM-4KL24	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05703
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.72398
CCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21692
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
lung	GeneRIF Biological Term Annotations	1.0	null
GLIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.4909
YY1_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TADA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69777
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6378
SP5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.6779
biosynthetic process	GO Biological Process Annotations 2015	1.0	null
PARD6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63693
Lung adenocarcinoma_LUAD_TCGA-55-A492-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GLS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90483
SF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4108
Nitrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.737
POLR2A_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EIF4B	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN015_HEPG2_48H:H04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.37268
AGTRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09838
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.84106
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51903
MBD4_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-REY6-1226-SM-48FDR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34182
GTEX-UJMC-2026-SM-3GADR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872444
GSE201454_1_v_4_ftcd_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PCM6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76943
Adrenocortical carcinoma_ACC_TCGA-P6-A5OG-01A-22R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27353
GATA1	ENCODE Transcription Factor Targets	1.0	null
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4306
gain	GeneRIF Biological Term Annotations	1.0	null
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NUDT4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32856
USP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89891
andor	GeneRIF Biological Term Annotations	1.0	null
TRMT6	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
AMPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42716
VPS13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53843
POLR2A_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.841532
SERPING1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20142
IRAK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12919
H3K4me1_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN011_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1128
SUM149PT	DepMap CRISPR Gene Dependency	1.0	2.58933
Bb-3497	DrugBank Drug Targets	1.0	null
THG1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.6565
GSE229973_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.29419
GTEX-NL4W-0011-R11A-SM-2I3DW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41401
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.910412
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S13-Table_S13_MR_resluts_of_brain_pQTL_and_large-artery_atherosclerotic_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN017_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.95796
co-translational protein modification	GO Biological Process Annotations 2015	1.0	null
CRCGN017_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.36825
ELK4_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COQ4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56056
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NFATC1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWN1-1526-SM-48TDA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.985818
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE201309_1_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE161771_0_v_1_secretin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-V1D1-0008-SM-4JBIJ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08169
YY1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4K91ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38908
GSE137177_2_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RNF112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23301
Lung squamous cell carcinoma_LUSC_TCGA-92-7341-01A-31R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.WT.HP_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4546
MRPL30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55379
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
YY1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE223893_11_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GABPA_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0726-SM-4B659	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42866
GA-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52797
Lung squamous cell carcinoma_LUSC_TCGA-77-6845-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AB-17-WP43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.581099
LIG3	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SP9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	83.2566
ND-39-PO34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.349277
ZNF263	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6273
KB-46-EJ60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.440495
USP38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78711
DNAJC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89372
peptidyl-amino acid modification	GO Biological Process Annotations 2015	1.0	null
Bile	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.874
CRCGN016_MCF10A.WT.HP_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.53506
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00858
RPS24	Pathway Commons Protein-Protein Interactions	1.0	null
496100468_PCx_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.04774
NFIC	ENCODE Transcription Factor Targets	1.0	null
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.08452
KA-29-AB08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.543718
CA-42-YI34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.319049
OB-20-LP90_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.397453
fallopiantube_8b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.94509
toxin-antitoxin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.174
TRIB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10702
SKMM2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65114
BA-84-WN26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.367184
E2F4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
GTEX-TMMY-0526-SM-33HBC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1357
TAF15	Pathway Commons Protein-Protein Interactions	1.0	null
H3K36me3_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04357
H3K36me3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE166783_8_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5400-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-556-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
CAPN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53962
GSE140997_4_v_8_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Plastid nucleoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.65
Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YO-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KLF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.4394
GSE248883_0_v_1_shmt2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA3	ENCODE Transcription Factor Targets	1.0	null
TOX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64595
TAF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:A22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.42663
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.825889
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5678-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Thylakoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.205
Aspartate carbamoyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.679
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61851
GABPA_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JB-75-NC66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.32962
WHSC1	ENCODE Transcription Factor Targets	1.0	null
GSE196505,GSE196507_1_v_2_kdm2b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DAXX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41067
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21765
Acute Myeloid Leukemia_LAML_TCGA-AB-2979-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TE10	CCLE Cell Line Gene CNV Profiles	1.0	1.63726
FAM120AOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80984
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TSE9-0011-R11A-SM-3DB7N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02946
GTEX-PWO3-0011-R1A-SM-2I5EW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.941517
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08739
NCI-H1650	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.37462
HR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80724
C19orf25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.05957
heart muscle	HPA Tissue Protein Expression Profiles	1.0	1.93179
L-cysteine desulfurase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.04
CRCGN008_HEPG2_24H:J15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0944
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32014
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.72398
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.925798
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
IK	Pathway Commons Protein-Protein Interactions	1.0	null
Nymph	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.745
CRCGN010_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.27491
YY1AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11286
SNU-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26248
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE169691_1_v_2_saha_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
JD-81-YX02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.645522
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GYS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81237
496100427_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.0518
NFIC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-M7-A71Z-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Macrolide transmembrane transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.818
WIZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75718
Photosynthetic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.241
NFIC_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NSUN2	Pathway Commons Protein-Protein Interactions	1.0	null
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.05141
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFX5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FB-66-UU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.760057
PMC12712253-12672_2025_4014_MOESM1_ESM.xlsx-Table_S4-Table_S4_The_result_of_MR_analysis_for_PC_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
XXYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61614
NCIH209	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50418
DPY30	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-T5JC-1526-SM-4DM68	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878362
RASD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.65596
TBK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13388
RPS15A	Pathway Commons Protein-Protein Interactions	1.0	null
DB-54-GQ68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.503452
EP300_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-94-A4VJ-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LPS6	DepMap CRISPR Gene Dependency	1.0	4.47839
pyrroline-5-carboxylate reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.511
PRPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05201
FA-63-WI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.277608
GTEX-WOFM-1726-SM-3MJFA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30611
Brain Lower Grade Glioma_LGG_TCGA-HT-A74K-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN010_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.43696
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5470-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_astrocyte of the spinal cord_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OL-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PNRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04007
ZNF70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30625
GTEX-T6MN-0002-SM-3NMAH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82763
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE179880_10_v_13_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4761-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE97278,GSE97280_2_v_1_nsd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OHPL-0326-SM-33HC8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17865
CTV1DM	DepMap CRISPR Gene Dependency	1.0	6.30272
PHACTR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47187
DUS3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20478
SGPL1	Pathway Commons Protein-Protein Interactions	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
GSE203158_0_v_13_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11365
TGBC52TKB	DepMap CRISPR Gene Dependency	1.0	2.39762
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32316
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4514-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLEK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44204
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09671
TRIP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76107
TPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54361
TEX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72645
JUND_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A6J3-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Exosome (RNase complex)	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.864
POLR2A_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.998001
Esophageal Varices	DisGeNET Gene-Disease Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4621-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QDT8-0011-R11A-SM-32PKD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17648
CRCGN015_HEPG2_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.88184
LSM1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34936
GTEX-RN64-1226-SM-2TC6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.07949
UBALD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17344
cellular_component	GO Cellular Component Annotations 2015	1.0	null
CRCGN008_HEPG2_24H:G24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.90975
PMC12706077-44318_2025_598_MOESM21_ESM.xlsx-Dataset_EV19-hKidney_TPP-PISA-Genes_ZNF568	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U412-0008-SM-4DXTE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15446
CRCGN015_HEPG2_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.07375
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MRGBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17353
GTEX-QMR6-0011-R2A-SM-32PKV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09513
RPS8	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6IJ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18109
eGFP-GATA2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8025515-12859_2021_4105_MOESM12_ESM.xlsx-PW1-gene_stable_id_PEG3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-N7MT-0011-R2a-SM-2I3GI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45388
GSE151782_3_v_7_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TMEM129	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82161
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.69049
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Cytochrome b6f complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.673
AKT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73399
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ELF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2228	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.82722
cellular protein modification process	GO Biological Process Annotations 2015	1.0	null
KLF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.0438
DDX6	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AP-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chr16_69338024_A_G_b38	GTEx eQTL 2025	1.0	1.63365
provide	GeneRIF Biological Term Annotations	1.0	null
GTEX-XYKS-1726-SM-4E3IO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15134
CRCGN016_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.22242
HNRNPK	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF512	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86881
GP2D	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.67622
hsa-miR-3191	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
NFATC2IP	Pathway Commons Protein-Protein Interactions	1.0	null
GSE160817_4_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
ELF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMH2	CCLE Cell Line Gene CNV Profiles	1.0	2.03029
SNRPA1	Pathway Commons Protein-Protein Interactions	1.0	null
EGR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	78.4171
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.913361
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
lines	GeneRIF Biological Term Annotations	1.0	null
PMC12498101-cd-24-1904_supplementary_tables_s1-s12_suppst1.xlsx-S7-Supplementary_Table_7_Human_tissue_RNA-seq_differential_analysis_for_SPOPmut_vs_SPOPwt_AA_vs_AG_and_AG_vs_GG_clone_data_DEG_set_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN014_HEPG2_3H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.59775
CLEC14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26651
ZER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41512
GSE166783_3_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
i-AAA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.064
TAT protein transport complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.052
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.72398
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DRG1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN012_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.12804
GSE165548_2_v_13_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Sarcoma_SARC_TCGA-DX-A8BS-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74575
NCI-H358	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.16526
CCDC22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36261
lb4	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.727
MAX_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.04884
USF1_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6366-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963293
CRCGN012_HEPG2_24H:J20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.17174
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.218
OARD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53019
BCL7C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40929
CTCF_GM12870_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IGF2BP3	Pathway Commons Protein-Protein Interactions	1.0	null
cation binding	GO Molecular Function Annotations 2015	1.0	null
PMC8986528-41586_2022_4598_MOESM6_ESM.xlsx-Fig_4f-NOL9_KD_upreg_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CLASP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58445
ZNF277	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34989
H3K36me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26355
GTEX-SJXC-0426-SM-2XCFH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.902749
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06704
H3K79me2_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
thyroid gland	HPA Tissue Gene Expression Profiles	1.0	0.929617
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SRSF11	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN009_HEPG2_24H:H03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.66968
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MOGS	Pathway Commons Protein-Protein Interactions	1.0	null
USF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
metal ion binding	GO Molecular Function Annotations 2015	1.0	null
H4K20me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56831
A3/KAW	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30516
SMIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67912
GTEX-NPJ8-0011-R4a-SM-2HML3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21631
496100339_HIP_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.11642
GABPA_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AI-0926-SM-48U1F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02941
GSE151782_2_v_5_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JUN	ENCODE Transcription Factor Targets	1.0	null
POLR2AphosphoS5_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4490-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-MN-A4N4-01A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.865745
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79281
PKNOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96209
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BE-38-UW72_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.916558
ERCC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60649
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTMR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62397
MYC_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR2C2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LE-80-QM43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20658
hsa-miR-4769-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.55701
GTEX-S4UY-0006-SM-3K2A7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.951115
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3Y7-01A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_K562_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZC3H15	Pathway Commons Protein-Protein Interactions	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7UY-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HDLM2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53389
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
RAD21_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AI-0226-SM-48U1D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00145
Bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.444
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.665771
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4088
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70O-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
polyadenylation	GeneRIF Biological Term Annotations	1.0	null
FNBP1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48369
PSMD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44938
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.915324
H3K36me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00628
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL3H-0011-R2a-SM-2I3GG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1792
positions	GeneRIF Biological Term Annotations	1.0	null
KMS12BM	Achilles Cell Line Gene Essentiality Profiles	1.0	1.0283
lack	GeneRIF Biological Term Annotations	1.0	null
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37891
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DGKA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25489
FKBP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02496
CA-75-HA22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.727361
RPP30	Pathway Commons Protein-Protein Interactions	1.0	null
SHCBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66041
OE-84-HO42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.247871
BZW1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67921
CRCGN015_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.27729
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.14324
HNRNPR	Pathway Commons Protein-Protein Interactions	1.0	null
C1orf115	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76829
BD-96-HO33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.441381
Commensal bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2H1-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.WT.HP_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.41938
stomach_3b	HPA Tissue Sample Gene Expression Profiles	1.0	1.10397
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.33376
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.925798
GTEX-R53T-2026-SM-3GIJF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0203
GTEX-NPJ7-0011-R4a-SM-2I3GJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48971
C-33 A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.904302
estradiol_homo sapiens_gpl570_gse5102	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE125153_2_v_0_bcl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Body mass index	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.0301
GTEX-TML8-0001-SM-3NMAF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32413
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.910412
POU2F2_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.91683
Translation release factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.654
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.18269
GSE191174_0_v_1_ccdc92_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RPL5	Pathway Commons Protein-Protein Interactions	1.0	null
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.101
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.05615
GSE127790_10_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213588_9_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MacAB-TolC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.003
P30-OHK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-U8T8-0126-SM-3DB94	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3371
CFPAC1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.15513
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4842-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7697260__F4	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-TKQ1-0003-SM-3NMAE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.048
FAM200A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60822
H3K36me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACTR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02221
496100466_PCx_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05948
TAF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.21168
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.863659
RPS28	Pathway Commons Protein-Protein Interactions	1.0	null
PEG10	Pathway Commons Protein-Protein Interactions	1.0	null
CSNK1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52118
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7046-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WVLH-0011-R8A-SM-3MJFC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09862
CAL148	CCLE Cell Line Gene CNV Profiles	-1.0	-2.18969
ERG	ChEA Transcription Factor Targets	1.0	null
GSE162739_7_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OOBJ-0008-SM-3NB26	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53914
RABEP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98313
GTEX-S7PM-0011-R6A-SM-3NM8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07196
GUF1	Pathway Commons Protein-Protein Interactions	1.0	null
TOR1AIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93333
GSE212330_1_v_0_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PEX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50668
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.77486
OV-56	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.06945
TEAD4_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
samestrand	GeneRIF Biological Term Annotations	1.0	null
SRP14	Pathway Commons Protein-Protein Interactions	1.0	null
HNRNPD	Pathway Commons Protein-Protein Interactions	1.0	null
dh82	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.556
YY1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P44H-0008-SM-48TDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51398
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QC-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Type IV secretion system complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.028
ELAVL1	Pathway Commons Protein-Protein Interactions	1.0	null
Tfcp2l1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.2777
STOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64437
TAF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fluorouracil	CTD Gene-Chemical Interactions	1.0	null
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06086
PMC10830421-41589_2023_1452_MOESM5_ESM.xlsx-HEK293T_MAX-Tg_tissues-Unnamed_0_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.829617
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-3.56336
GTEx AdiposeTissue 20-29 vs 30-39	GTEx Tissue-Specific Aging Signatures	-1.0	-6.51558
PACS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06337
TRIM28_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.011
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M7-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_id_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
CXCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4663
HMGB1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE205316,GSE205317_0_v_1_nrip1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE199874_3_v_5_gabpb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DA-35-DU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.411021
endometrium_8a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.36314
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07266
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.64258
GSE131649_2_v_0_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN011_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6474
BHY	DepMap CRISPR Gene Dependency	1.0	2.22131
H3K36me3_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNRNPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88249
primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.67368
FA-63-WI26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.342557
GTEX-QVUS-0008-SM-447AY	GTEx Tissue Sample Gene Expression Profiles	1.0	2.21776
ALAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05472
C170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.836865
SIX5	ENCODE Transcription Factor Targets	1.0	null
ott1_22490678_hematopoietic_stem_cell_lof_mouse_gpl8321_gds4315	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.065766
CRCGN017_MCF10A.WT.HP_24H:O09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.824
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
colonrectum_a	HPA Tissue Sample Gene Expression Profiles	1.0	0.886532
ACHN	CCLE Cell Line Gene CNV Profiles	1.0	1.46508
HMGB2	Pathway Commons Protein-Protein Interactions	1.0	null
NMT1	Pathway Commons Protein-Protein Interactions	1.0	null
SNU668	DepMap CRISPR Gene Dependency	1.0	4.48359
MAX	ENCODE Transcription Factor Targets	1.0	null
STK25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79896
NCIH28	DepMap CRISPR Gene Dependency	1.0	2.12415
Lung adenocarcinoma_LUAD_TCGA-55-7570-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148066,GSE157787_0_v_1_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.222
FXR1	Pathway Commons Protein-Protein Interactions	1.0	null
GEMIN5	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U3ZM-0008-SM-4DXTQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90657
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	1.0	2.24053
ATF3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49674
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REC1	CCLE Cell Line Gene CNV Profiles	1.0	1.46367
Lung adenocarcinoma_LUAD_TCGA-86-A4D0-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GABP-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
488395315_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.04736
BA-72-YP01_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.206594
RELA	ENCODE Transcription Factor Targets	1.0	null
EE-04-QG34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.206083
CRCGN016_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.06525
TLE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33306
ELF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4494-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-FB-A5VM-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN009_HEPG2_24H:H04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.37498
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35275
CPSF7	Pathway Commons Protein-Protein Interactions	1.0	null
PLEKHA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23718
GTEX-WFG8-0126-SM-4LVMH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969021
Acute Myeloid Leukemia_LAML_TCGA-AB-2875-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LUC7L	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN011_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.0844
CBX3	ENCODE Transcription Factor Targets	1.0	null
Subesophageal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.509
INPPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6858
RPS10	Pathway Commons Protein-Protein Interactions	1.0	null
HNRNPDL	Pathway Commons Protein-Protein Interactions	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
SATB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41467
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
C6orf141	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80187
SLC35E4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77809
ATXN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0325
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.912749
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-Fay_Heat_LPStoThermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
UF-14-LK87_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.296087
AP5M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82543
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74088
REST_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X638-0326-SM-47JY1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27825
ACHN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.856212
GTEX-TSE9-0726-SM-3DB8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44353
FZD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77944
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.967783
ZNF384	ENCODE Transcription Factor Targets	1.0	null
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00942
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C3orf38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80225
CRCGN015_HEPG2_48H:G04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.16112
RXRA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AC-36-SY22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.279553
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TMMY-1126-SM-4DXSX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01609
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.32726
GSE186287_2_v_0_ufm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HSFY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17109
ZBED4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	139.741
GTEX-R55F-0011-R8A-SM-2TF4F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5474
RPS27	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-U3ZN-0826-SM-4DXSZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01304
Internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-SUCS-0726-SM-4DM7J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3008
GTEX-U8XE-0826-SM-4E3J1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05837
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
those	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_HEPG2_48H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.90243
H3K4me1_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE139455_7_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CEP68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78549
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR2F2	ENCODE Transcription Factor Targets	1.0	null
regulation of cell population proliferation	GO Biological Process Annotations 2025	1.0	null
UB-83-HM84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.238142
GSE139455_4_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RAB43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01214
GSE139966_1_v_2_figla_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TP53	JASPAR Predicted Transcription Factor Targets	1.0	null
SERBP1	Pathway Commons Protein-Protein Interactions	1.0	null
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Squamous cell carcinoma of lung_Lung Tissue_GSE3268	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.17715
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSTCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97284
GSE122101,GSE122103_3_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TCF12_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-PQ-A6FN-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
THAP1	ENCODE Transcription Factor Targets	1.0	null
HCC2218	CCLE Cell Line Gene CNV Profiles	-1.0	-2.02298
SK-MEL-24	COSMIC Cell Line Gene Mutation Profiles	1.0	null
various	GeneRIF Biological Term Annotations	1.0	null
SLC2A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97691
DOT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55636
FLI1_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Abdominal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.505
ZNF521	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81436
NCIH650	DepMap CRISPR Gene Dependency	1.0	4.84751
PMC3879300-pone.0084292.s002.xlsx-SPD_dataset-Gene_symbol_HOXD13	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U3ZH-0008-SM-4DXT2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24358
C8166	DepMap CRISPR Gene Dependency	1.0	6.34134
BCLAF1	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF1	ENCODE Transcription Factor Targets	1.0	null
COLO-783	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.24687
AC-30-XU83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.52863
ETS1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN009_HEPG2_24H:F05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.07604
TGIF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21206
GA-30-HJ41_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.240417
JC-02-ZR15_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.373568
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYOG_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FBL	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-X4XY-0326-SM-46MVZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00263
OSTM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21357
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7154-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Parasitic infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.134
GTEX-TKQ2-0226-SM-4DM6V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34486
H3K18ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Small ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.502
ZEB1	ENCODE Transcription Factor Targets	1.0	null
GSE140997_4_v_5_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
RPS29	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WFG7-2326-SM-3GIKV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872522
RPS26	Pathway Commons Protein-Protein Interactions	1.0	null
GSE119978,GSE180930_6_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A728-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LD-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DBR1	Pathway Commons Protein-Protein Interactions	1.0	null
ALG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46363
SMARCC1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-PSDG-1326-SM-48TD2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30934
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PWCY-0726-SM-48TCS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965382
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ICAM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30406
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
report	GeneRIF Biological Term Annotations	1.0	null
LNZTA3WT4	DepMap CRISPR Gene Dependency	1.0	2.07235
POLR1C	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN009_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.42495
Plastid chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.923
BAG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54388
GSE239844_6_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-SNOS-0326-SM-4DM6C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927184
GTEX-TKQ2-0008-SM-4DM5L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961059
GSE142684_3_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14585
SFPQ	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RNF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.82904
USTEKINUMAB	DGIdb Drug Targets 2026	1.0	0.330825
496100328_TCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.05175
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RK-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.906502
Formylmethionine deformylase	InterPro Predicted Protein Domain Annotations	1.0	null
EIF2S3	Pathway Commons Protein-Protein Interactions	1.0	null
separase-securin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.586
CRCGN015_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0119
GTEX-X4XY-1626-SM-46MVN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29682
GTEX-XV7Q-1526-SM-4BRWB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07924
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
cerebellar cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.27476
TGFBR1_knockdown_102_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.82848
SRRT	Pathway Commons Protein-Protein Interactions	1.0	null
HD-51-KD29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.453743
KYSE150	Achilles Cell Line Gene Essentiality Profiles	1.0	1.06506
GTEX-NPJ7-0011-R9a-SM-2TC5R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.914001
GSE139966_1_v_0_figla_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149264,GSE149267_9_v_1_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PML_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLK1	Pathway Commons Protein-Protein Interactions	1.0	null
BDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98812
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AD-16-HL96_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.897083
GTEX-OHPN-0011-R7A-SM-2I5FI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69256
Lung adenocarcinoma_LUAD_TCGA-44-6774-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN010_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.496
mitochondrion	LOCATE Predicted Protein Localization Annotations	1.0	null
PHF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97368
BCL3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
WASHC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93155
496100301_TCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.05233
CCNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93669
HSPA9	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
UF-27-HS98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.720873
TAF1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24694
NCIH1048	CCLE Cell Line Gene CNV Profiles	-1.0	-1.90137
ME-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.80873
TEX261	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38809
NFATC1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBM42	Pathway Commons Protein-Protein Interactions	1.0	null
IGF2BP1	Pathway Commons Protein-Protein Interactions	1.0	null
ATF3	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7579-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE218879_1_v_2_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
protein modification process	GO Biological Process Annotations 2025	1.0	null
GABARAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61522
GABPA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MT-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.31556
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
WASHC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38145
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06579
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE207787_3_v_2_pdha1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GABPA_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PIAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78495
GTEX-QMR6-0011-R11A-SM-32PKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10293
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.261499
Phellem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.635
GTEX-U4B1-0008-SM-4DXUW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06375
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RPS25	Pathway Commons Protein-Protein Interactions	1.0	null
AU565	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4184
GTEX-QDT8-0926-SM-32PL2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52981
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02192
salivarygland_6c	HPA Tissue Sample Gene Expression Profiles	1.0	0.835031
Brain Lower Grade Glioma_LGG_TCGA-QH-A65X-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XYKS-0526-SM-4BRW2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843151
SNRPD3	Pathway Commons Protein-Protein Interactions	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A852-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BEND6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39567
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
GSE231648_0_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DHCR24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97267
NZM42	DepMap CRISPR Gene Dependency	1.0	3.50031
ZNF765	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96957
SCAMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01865
gp16	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.554
HIPK2_defectivemutant_17_GDS1793	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.23494
GJA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32838
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC9084694-RMB2-21-e12464-s005.xlsx-GV_MI_MII_GV-up-GeneName_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158815_1_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148269,GSE148273_0_v_1_arid4b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H3-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TRIM28_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.79897
ARF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83908
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Farage	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.44218
kidney_a	HPA Tissue Sample Gene Expression Profiles	1.0	2.27483
hsa-miR-509-3-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
CORO1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09353
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
smoothmuscle_8a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.13022
OAW42	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56831
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.527
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NRN1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66505
GSE165548_2_v_7_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE240027,GSE240030_5_v_3_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PROCR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16111
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETS1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07357
ATP1B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3952
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CF-91-JY05_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.267861
Brain Lower Grade Glioma_LGG_TCGA-HT-A61C-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUB1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE128099,GSE128159_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RNOR-1226-SM-48FDQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935777
RPS23	Pathway Commons Protein-Protein Interactions	1.0	null
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2823
REST_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
FSTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77051
GSE131660_2_v_0_piperlongumine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78582
CRCGN013_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.41805
NE-94-VE83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.301201
EHEB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RFC1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC5072418__F1	PFOCR Pathway Figure Associations 2024	1.0	null
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPU-0011-R5A-SM-2XCAD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00064
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCFL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.398
BICR 22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.09323
ion binding	GO Molecular Function Annotations 2015	1.0	null
RPL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43754
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.84765
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GC-04-UF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.348001
CCNG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0647
GSE168602,GSE168604_2_v_1_selumetinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49058
Brain Lower Grade Glioma_LGG_TCGA-DU-A7T6-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.553
turnover	GeneRIF Biological Term Annotations	1.0	null
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.863766
E2F1	ENCODE Transcription Factor Targets	1.0	null
RNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68672
POU2F2_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:F13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.30901
NPTXR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2339
GSE201309_4_v_2_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.19588
ZNF682	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.948
CRCGN014_HEPG2_24H:H21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.27851
translation	GO Biological Process Annotations 2015	1.0	null
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TUBB	Pathway Commons Protein-Protein Interactions	1.0	null
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.9156
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.284
USF1	ENCODE Transcription Factor Targets	1.0	null
CRCGN015_MCF10A.WT.HP_24H:J06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00766
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26355
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A65B-01A-12R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ERMAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06739
GTEX-POMQ-0126-SM-48TD6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840446
AE-42-HT01_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.25139
SRRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68092
SMC3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RUSQ-0226-SM-47JWT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97703
EIF3A	Pathway Commons Protein-Protein Interactions	1.0	null
HTR3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57928
evolution	GeneRIF Biological Term Annotations	1.0	null
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.721
UBAP2L	Pathway Commons Protein-Protein Interactions	1.0	null
PCBP2	Pathway Commons Protein-Protein Interactions	1.0	null
Mesothelioma_MESO_TCGA-MQ-A6BN-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DC-49-EJ23_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.374859
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5868
SMIM12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11463
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35275
GSE213228_2_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
HNRNPA2B1	Pathway Commons Protein-Protein Interactions	1.0	null
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EXOSC6	Pathway Commons Protein-Protein Interactions	1.0	null
AF-99-HA02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.707239
CRCGN015_HEPG2_48H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.27351
GTEX-S341-0008-SM-4AD6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78474
GSE73561,GSE73563_0_v_1_mef2c_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IM-95M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100433_HIP_probable Alzheimer's disease_TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.05202
CRCGN015_HEPG2_48H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.46895
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14561
GSE135400_1_v_0_kdm1b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
496100542_PCx_no dementia_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.04964
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
C12orf43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4751
TARS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29101
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.86643
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2E	Pathway Commons Protein-Protein Interactions	1.0	null
A549	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.945847
TNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44576
NR4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07529
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JN-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DPP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12565
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5864
CRCGN015_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.87752
PMC11385366-Table2.xlsx-DBP-Overlapped_Gene_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
NUAK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24952
LRP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19588
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_HEPG2_48H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06968
PMC5263239-mmc2.xls-SEM_siMLL-AF4-MLL-AF4_gene_targets_with_decrease_in_MLL-AF4_ChIP-seq_signal_2198_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
Middle East Respiratory Syndrome	DisGeNET Gene-Disease Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VM-A8C9-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4279
PMC8410083-elife-65574-fig7-data1.xlsx-KLF10_network-Genes_bound_by_KLF10_in_their_-10_1kb_region_or_differentially_expressed_in_WT_vs_HepKO_hepatocytes_challenged_with_high_sugar_KLF10	Rummagene Transcription Factor Associations 2026	1.0	null
TAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Photosystem I	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.678
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ATIC	Pathway Commons Protein-Protein Interactions	1.0	null
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NANOG	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EN-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PSDG-0008-SM-48TE5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42907
GTEX-XYKS-0426-SM-4BRW4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834584
GSE125025_2_v_3_lyl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PNPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02564
GSE96641_1_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ANPR-A receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.957
Mitochondrial ribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.787
RPS4X	Pathway Commons Protein-Protein Interactions	1.0	null
BC-25-VR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.818182
LN235	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.39902
MAX_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_astrocyte of the spinal cord_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNRNPA3	Pathway Commons Protein-Protein Interactions	1.0	null
CREM	ChEA Transcription Factor Targets	1.0	null
18081427-TableS7	GeneSigDB Published Gene Signatures	1.0	null
TBC1D25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76973
hek293	HPA Cell Line Gene Expression Profiles	1.0	1.85388
GTEX-XUZC-2126-SM-4BRW8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921381
AA-58-FJ71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.11101
DPP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69331
GSE209898,GSE209899_0_v_1_flcn_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC5474565-onc2016488x2.xlsx-Table_S4_MLL_Target_Genes-THP-1_MLL-AF9_target_genes_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HG-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BICD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95359
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.41281
CRCGN015_MCF10A.TP53.M_24H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.8999
HNRNPLL	Pathway Commons Protein-Protein Interactions	1.0	null
GSE223241_2_v_0_cdkn2a_human	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A42Y-01A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RMDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80291
GSE238116_1_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-A5G7-01B-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.04731
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
MAMLD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15221
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.36378
CRCGN010_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.34622
adrenal gland	HPA Tissue Protein Expression Profiles	1.0	1.93179
GTEX-N7MS-0926-SM-2HMIZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.961333
GTEX-RVPU-0011-R7A-SM-2XCAB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54591
GTEX-NPJ8-0011-R1a-SM-33HCB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12902
Lung squamous cell carcinoma_LUSC_TCGA-18-3412-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DDX42	Pathway Commons Protein-Protein Interactions	1.0	null
GTF2B	Pathway Commons Protein-Protein Interactions	1.0	null
mechanistic	GeneRIF Biological Term Annotations	1.0	null
estradiol_homo sapiens_gpl570_gse23610	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RNASEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75488
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89329
DUS3L	Pathway Commons Protein-Protein Interactions	1.0	null
ECC10	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38823
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
signals	GeneRIF Biological Term Annotations	1.0	null
POLR2AphosphoS5_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE206516,GSE206518_3_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SNRPD2	Pathway Commons Protein-Protein Interactions	1.0	null
Thymus	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.73545
GLIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.4029
PMC6078963-41467_2018_5311_MOESM5_ESM.xlsx-48h_KD_UP_Vs_ATAC-z_e_o_To_AR	Rummagene Transcription Factor Associations 2026	1.0	null
LYZ	Pathway Commons Protein-Protein Interactions	1.0	null
BFTC905	DepMap CRISPR Gene Dependency	1.0	4.60119
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.33314
TXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79591
BRCA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BGN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82234
EML4	Pathway Commons Protein-Protein Interactions	1.0	null
DA-35-DU85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.2941
KLF16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4041
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE213588_10_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TCF3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03185
BDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46586
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVJO-0008-SM-447AU	GTEx Tissue Sample Gene Expression Profiles	1.0	2.4503
MXI1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RTL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.03407
POLD1	Pathway Commons Protein-Protein Interactions	1.0	null
MAP2K1_knockdown_105_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.70448
MYORG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74921
CEPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12015
HSPA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32633
appendices_4a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.16749
chr16_69315882_T_C_b38	GTEx eQTL 2025	1.0	1.15644
CRCGN017_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.8964
primary motor cortex (area M1, area 4)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10415
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2897
GSE195559_8_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NUDT21	Pathway Commons Protein-Protein Interactions	1.0	null
GLI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.579
GYG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97575
LN18	DepMap CRISPR Gene Dependency	1.0	3.06455
seems	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.83398
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU16	CCLE Cell Line Gene CNV Profiles	1.0	1.54592
POLR2A_K562_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PEA1	DepMap CRISPR Gene Dependency	1.0	2.39171
C2CD4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.44748
PJVK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68736
EBF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-OHPK-0008-SM-4E3JL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901512
MTMR12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75577
POLR2A_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3218
GSE119978,GSE180930_0_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
IGF2BP2	Pathway Commons Protein-Protein Interactions	1.0	null
TMEM187	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8381
BCL7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-4098-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PDLIM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32466
GSE213048_1_v_2_irf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JUND_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mitochondrion	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
JE-72-KV75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.819865
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.10503
GSE118794_5_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SRSF7	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89691
GSE151782_2_v_7_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ELK4	ENCODE Transcription Factor Targets	1.0	null
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLITRK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68817
MXI1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100337_HIP_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.05005
PAX5	ENCODE Transcription Factor Targets	1.0	null
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.0802
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dbtrg05mg	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.116
UBE2S	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00151
HCFC1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAU2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70755
PMC12478325-12672_2025_3468_MOESM1_ESM.xlsx-Table_S9-Table_S9_Results_of_MR_analysis_between_druggable_genes_eQTLs_and_CrNEN_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0753
ZNF300	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86258
GSE172146_2_v_1_mettl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T5JW-0008-SM-4DM5X	GTEx Tissue Sample Gene Expression Profiles	1.0	2.20866
MPHOSPH9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23419
smooth muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.01551
HIF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09506
TRIMETREXATE	DGIdb Drug Targets 2026	1.0	0.735167
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.88805
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NFYB	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K36me3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCP1_02_194	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.5993
LA-42-ER00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.270275
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.834932
C1QTNF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06698
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:H02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01505
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ERG-21242973-JURKAT-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_HEPG2_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.00294
POLR2A_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPL8	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF610	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	162.336
TCCSUP	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.30792
NCL	Pathway Commons Protein-Protein Interactions	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2910-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K36me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NB-80-IM48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.87979
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5605
HCC78	DepMap CRISPR Gene Dependency	1.0	2.07943
GSE119978,GSE180930_0_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Thoracic ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.664
SDCBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39657
Lung adenocarcinoma_LUAD_TCGA-55-1596-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NSMF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15958
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.58958
PMC13187244-41392_2026_2766_MOESM2_ESM.xlsx-Table_S18-Table_S18_Differentially_expressed_genes_in_OCI-AML3_cells_ZMIZ1_inhibitor_SIH-002_4H_vs_DMSO_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CCDC184	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3152
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
FOXM1	ENCODE Transcription Factor Targets	1.0	null
LHX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45208
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.977137
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.11133
hsa-miR-520h	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
CRCGN015_HEPG2_48H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.7227
PUF60	Pathway Commons Protein-Protein Interactions	1.0	null
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FECH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81011
HLF	Achilles Cell Line Gene Essentiality Profiles	1.0	1.0193
FUS	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OXRN-0526-SM-2I5EN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889203
kidney_d	HPA Tissue Sample Gene Expression Profiles	1.0	0.97091
HLA-A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.22705
H4K8ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.73932
496100558_PCx_probable Alzheimer's disease_TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.05128
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.64746
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10779
GSE148066,GSE157787_3_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RUNX3	ENCODE Transcription Factor Targets	1.0	null
C2orf49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87266
GTEX-WFJO-0008-SM-4LVN7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.321
GSE229309,GSE229314_4_v_1_elavl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE111247_2_v_8_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH322	CCLE Cell Line Gene CNV Profiles	1.0	1.54547
496100537_FWM_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.0495
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64634
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6391560__F6	PFOCR Pathway Figure Associations 2024	1.0	null
PSPC1	Pathway Commons Protein-Protein Interactions	1.0	null
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.837636
dactinomycin_homo sapiens_gpl7172_gse12459	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MFSD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34197
GSE140937,GSE140938_1_v_2_slfn11_human	RummaGEO Gene Perturbation Signatures	1.0	null
HCV JFH-1_12Hour_20200238_GSE20948	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.85063
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.859107
S0-EE-Y737_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.229985
m-AAA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.335
SPI1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5369
OV-7	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.809
GSE168602,GSE168604_2_v_6_selumetinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FAM124B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49374
PMC8859258__F4	PFOCR Pathway Figure Associations 2024	1.0	null
MYL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76172
LSM12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55621
GTEX-VJYA-0726-SM-4KL1T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84316
DECR1	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67O-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.26015
GTEX-R53T-0326-SM-48FEC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31906
CRCGN015_MCF10A_48H:F02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1032
HBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54714
CCDC88C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9386
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
AA-86-YY62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.213132
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0048
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.12181
UBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00102
HMOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36036
NALM-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.0909
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8046-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.7495
GSE124375_10_v_9_chd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12663470-41467_2025_65818_MOESM3_ESM.xlsx-Data_S17-Data_S17_One-sample_MR_for_replicated_SCZ_risk_genes_for_each_omics_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Ribonuclease P complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.928
ENO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47175
E2F4	ChEA Transcription Factor Targets	1.0	null
CRCGN012_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.44857
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	GO Molecular Function Annotations 2015	1.0	null
GMFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33041
GSE104508_0_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KF-18-RY71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.237266
Molting gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.802
GSE131649_2_v_9_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HEC59	DepMap CRISPR Gene Dependency	1.0	9.15447
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CAL-72	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF93	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7929
Neurologic Manifestations	CTD Gene-Disease Associations	1.0	1.09998
PMC11953091-12035_2025_4695_MOESM1_ESM.xlsx-s5-Supplementary_Table_5_Results_of_the_2-sample_pQTL_MR_on_insomnia_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-5420-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H4K91ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TMEM60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89422
THAP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66462
SD-69-QA40_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.212347
GTEX-T6MN-0011-R1A-SM-32QOY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.9467
CCDC136	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53744
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.969757
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DARS	Pathway Commons Protein-Protein Interactions	1.0	null
FAM229B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75984
FLI1	ChEA Transcription Factor Targets	1.0	null
SNRPD1	Pathway Commons Protein-Protein Interactions	1.0	null
PNN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01182
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
RPS12	Pathway Commons Protein-Protein Interactions	1.0	null
NFKB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.0775
POLR2AphosphoS2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4507-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H1F0	Pathway Commons Protein-Protein Interactions	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.85404
TRAPPC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93313
H3K27ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RBM14	Pathway Commons Protein-Protein Interactions	1.0	null
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
KYSE-450	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.55697
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-6.07884
Organellar small ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.542
GSE113734_1_v_0_qprt_human	RummaGEO Gene Perturbation Signatures	1.0	null
NFIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63357
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUJ4-0008-SM-4BOQI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859513
hippocampus (hippocampal formation)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.849717
TAF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNRNP200	Pathway Commons Protein-Protein Interactions	1.0	null
GSE237040_6_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cervicitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.109
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6756575__F3	PFOCR Pathway Figure Associations 2024	1.0	null
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.72398
CRCGN016_MCF10A.WT.HP_24H:F14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.19193
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cytosolic proteasome complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.607
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.08388
FUBP1	Pathway Commons Protein-Protein Interactions	1.0	null
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.54152
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE149264,GSE149267_4_v_5_trp53_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AS-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.WT.HP_24H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.65193
estradiol_homo sapiens_gpl1225_gse1486	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XV7Q-2126-SM-4BRVX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904756
TCF12_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HINT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80654
Protocerebrum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.733
primary somatosensory cortex (area S1, areas 3,1,2)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01689
GSE110440_2_v_3_rad21_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DNAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94586
SOX5	JASPAR Predicted Transcription Factor Targets	1.0	null
HS 578T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.886824
C14orf166	Pathway Commons Protein-Protein Interactions	1.0	null
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
Right_Atrium	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.878205
TCF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.7663
GSE142684_0_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
loss	GeneRIF Biological Term Annotations	1.0	null
prostate cancer	GAD Gene-Disease Associations	1.0	null
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5084-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7895828-41419_2021_3488_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_3_List_of_deregulated_genes_in_c-MYC_altered_human_HCC_from_TCGA_LIHC_dataset_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
cellular biosynthetic process	GO Biological Process Annotations 2015	1.0	null
YD-49-HM53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.892636
CRCGN008_HEPG2_24H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.78075
MYOG	ENCODE Transcription Factor Targets	1.0	null
AK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48473
Skin Cutaneous Melanoma_SKCM_TCGA-IH-A3EA-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUJ4-0126-SM-4BOP7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09006
IC-05-AW29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207498
ZIC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12611
TKFC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45916
CLDN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27842
CRCGN015_HEPG2_48H:J17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.915
KDM4A	ENCODE Transcription Factor Targets	1.0	null
TRMT61A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE137144_3_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CEBPD_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FD-91-OK66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.26063
SOX2-16153702-HESC-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
HNF4A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PCOLCE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52266
POU3F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43402
GSE183271_4_v_3_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
REST_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
KIF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4568
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.29585
CRCGN010_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.16458
WDFY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31885
RHOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83925
GTEX-QEL4-0526-SM-3GIJ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.883099
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4638-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10458
ERI1	Pathway Commons Protein-Protein Interactions	1.0	null
AD-77-UF99_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.33697
combined	GeneRIF Biological Term Annotations	1.0	null
CRCGN016_MCF10A.WT.HP_24H:D19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.00584
preservation	GeneRIF Biological Term Annotations	1.0	null
BT16	DepMap CRISPR Gene Dependency	1.0	4.23933
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
GTEX-T8EM-1626-SM-3DB7K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.983048
PRPF31	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_HEPG2_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.83566
GSE149124,GSE149128_3_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ONECUT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07625
NOL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50559
DIS3	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QESD-2026-SM-447BI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.96286
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.11548
SPI1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04033
OCIAML2	Achilles Cell Line Gene Essentiality Profiles	1.0	1.18688
molecular_function	GO Molecular Function Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7163-01A-12R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6K1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
GTEX-SNOS-0008-SM-4DM6I	GTEx Tissue Sample Gene Expression Profiles	1.0	3.24546
ELF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AKNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14372
USF2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AIMP2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TIM22 mitochondrial import inner membrane insertion complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.569
CDH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.755
process	GeneRIF Biological Term Annotations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A69H-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TFDP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.2372
AB-70-GR31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.482169
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytotoxic	GeneRIF Biological Term Annotations	1.0	null
GJB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04732
NDUFS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37688
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H1-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_24H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.02681
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_downreg-mouse_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE160817_7_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
KP3	CCLE Cell Line Gene CNV Profiles	1.0	1.34908
BCL3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VSIG10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67989
PMC5263239-mmc2.xls-SEM_-_MLL-AF4-All_targets_genes_names_2597_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
RBM15	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RVPV-0008-SM-47JYW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07966
Kidney renal papillary cell carcinoma_KIRP_TCGA-IZ-A6M8-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TIA1	Pathway Commons Protein-Protein Interactions	1.0	null
LACTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92613
Cytosolic ribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.365
PMC10290283-biol-2022-0622-sm3.pdf-293-ZNF429_ZNF429	Rummagene Transcription Factor Associations 2026	1.0	null
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TIGD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65286
FOSL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Outer membrane protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.538
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPD	ENCODE Transcription Factor Targets	1.0	null
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35434
GSE243491_3_v_0_oxaliplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
plicamycin_homo sapiens_gpl570_gse25127	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC4801062__F3	PFOCR Pathway Figure Associations 2023	1.0	null
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GA10	CCLE Cell Line Gene CNV Profiles	1.0	1.71796
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GNG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03775
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RTCB	Pathway Commons Protein-Protein Interactions	1.0	null
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.89138
COBLL1	Pathway Commons Protein-Protein Interactions	1.0	null
C1QBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01492
GSE218378_1_v_0_pbx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OHPN-0011-R4A-SM-2I5FD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24362
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51179
TRAF3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79478
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ESR1_ECC-1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFYA	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
S0-EE-Y79N_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.36882
POLR2AphosphoS2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC13000489-mmc1.xlsx-Table_S3-Table_S3_LC_related_genes_screened_by_MR_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_name_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39X-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TESK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97193
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.66717
PMC6078963-41467_2018_5311_MOESM5_ESM.xlsx-48h_KD_UP_Vs_ATAC-mgi_database_human_gene_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ZFP57	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.4139
ME1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.05916
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
substrate	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC3466441__F1	PFOCR Pathway Figure Associations 2024	1.0	null
Ewing's family tumor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.623
LIN7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22085
GTEX-S33H-1126-SM-2XCB6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07081
H2BK12ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MAP1LC3B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07997
WDR18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90108
PTPN14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36695
GSE139975_3_v_0_rnf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC2A14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9788
RPL26	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XLM4-0011-R9A-SM-4AT45	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09514
EBC1	CCLE Cell Line Gene CNV Profiles	1.0	1.77101
POLR2A_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01173
RAD21	ENCODE Transcription Factor Targets	1.0	null
cerebellum	HPA Tissue Protein Expression Profiles	-1.0	-1.19213
ETS1	ENCODE Transcription Factor Targets	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2937-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN012_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.00343
EBAG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73732
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN009_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.08653
SA-32-CC58_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.291985
EVSA-T	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.80774
SS18L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32565
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93636
SSB_02_107	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60163
thyroid_5c	HPA Tissue Sample Gene Expression Profiles	1.0	1.34621
Cell septum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.942
GTEX-RWSA-1126-SM-2XCAZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.825862
DNAJC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55534
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61962
PPP1CA	Pathway Commons Protein-Protein Interactions	1.0	null
SIN3A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210655_3_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SNRPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23243
PBX3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41743
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83S-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PML	ENCODE Transcription Factor Targets	1.0	null
CRCGN014_HEPG2_3H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.47185
ATF2_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100285_TCx_probable Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.05104
contribution	GeneRIF Biological Term Annotations	1.0	null
DHX9	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN010_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.34245
BT20	CCLE Cell Line Gene CNV Profiles	1.0	2.50334
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4713-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69051
MM1S	DepMap CRISPR Gene Dependency	1.0	4.86426
HMGN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45145
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
STOM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08361
GSE226316_11_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NEURL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87683
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.162
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12955
XPNPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81745
GTEX-O5YT-0008-SM-4E3IQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857813
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888671
Peripheral_Blood_Mononuclear_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.841144
CRCGN015_HEPG2_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.2415
SLFN13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71959
NCI-H1048	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.48515
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
TRMT9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37034
Hs-633T	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-1.86138
AB-92-LS83_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.234186
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cytochrome o ubiquinol oxidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.505
H3K36me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HC-74-HM63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.209752
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
GTEX-T5JW-1126-SM-4DM5V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902269
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JM-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AB-18-YN11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.435639
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
iron ion binding	GO Molecular Function Annotations 2015	1.0	null
MAFK	ENCODE Transcription Factor Targets	1.0	null
BT-20	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.25899
tn5b14	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.666
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39797
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74338
Type V protein secretion system complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.619
MIX23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66186
PMC10795826-jciinsight-8-170518-s128.xlsx-Fig_5B-Gene_Regulated_by_VDR_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
HS683	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.8708
YY1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE165122_0_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
KLF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	94.5547
Plant gall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.227
RPL3	Pathway Commons Protein-Protein Interactions	1.0	null
ZKSCAN1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.20419
AGAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6201
Liver hepatocellular carcinoma_LIHC_TCGA-5R-AA1D-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6499-01A-12R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Signal peptidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.917
CC-04-WK34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.338727
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EP-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
GTEX-XBEC-1326-SM-4AT69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69071
H3K9ac_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MAP2K7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95595
Lateral nerve cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.787
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3127-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.914338
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0117
SLC27A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32972
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6954-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LRRC8E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01453
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.20483
cellular macromolecule biosynthetic process	GO Biological Process Annotations 2015	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.393
CAMSAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49378
GSE201309_4_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7910854__F8	PFOCR Pathway Figure Associations 2024	1.0	null
RNMT	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-TSE9-0011-R9A-SM-3DB7Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.863676
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.212
GSE140441_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.79753
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB33_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF852	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84741
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DHX15	Pathway Commons Protein-Protein Interactions	1.0	null
GSE142430_2_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PRKCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54357
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.011
BC-61-BE07_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205324
NAMPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38611
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
NFIC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AD-98-UM13_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.218915
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NDUFAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65994
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
STAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.281
GTEX-NFK9-0926-SM-2HMJU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05177
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_24H:G03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0291
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LSM7	Pathway Commons Protein-Protein Interactions	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A4ZP-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.978464
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Polycystic Ovary Syndrome_Skeletal muscle_GSE6798	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.90396
CRCGN011_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.44655
PMC8564070-DataSheet1.docx-4-Supplementary_Table_5_the_correlation_of_ten_RNAs_with_MYCN_status_SD_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF782	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18185
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31577
KHSRP	Pathway Commons Protein-Protein Interactions	1.0	null
THAP1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
F2R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89496
HCST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16578
NRF1	ENCODE Transcription Factor Targets	1.0	null
GSE220058,GSE220059_0_v_1_prrc2b_human	RummaGEO Gene Perturbation Signatures	1.0	null
Apicoplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.603
origin	GeneRIF Biological Term Annotations	1.0	null
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X5EB-1926-SM-4E3IW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832763
protein modification process	GO Biological Process Annotations 2015	1.0	null
GSE166783_1_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZSCAN5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2354
GTEX-QMR6-0008-SM-447AV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45495
chr16_69328549_C_G_b38	GTEx eQTL 2025	1.0	1.69789
PML_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPK5-0226-SM-3GAEV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.964351
GSE159967_3_v_0_arid5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SUDHL1	CCLE Cell Line Gene CNV Profiles	1.0	1.66667
HNRNPF	Pathway Commons Protein-Protein Interactions	1.0	null
TFEB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7399
BTN3A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58781
RPL26L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20401
NDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47326
MRPS30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50904
GABPA_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
overexpressed	GeneRIF Biological Term Annotations	1.0	null
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UPIC-0926-SM-4IHLV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03994
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RPL24	Pathway Commons Protein-Protein Interactions	1.0	null
NCIH1993	DepMap CRISPR Gene Dependency	1.0	4.43776
Brain Lower Grade Glioma_LGG_TCGA-DU-6407-02B-11R-A36H-07,TCGA-DU-6407-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFON-0001-SM-3P61W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861503
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_1h-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
TEAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5912
RPS14	Pathway Commons Protein-Protein Interactions	1.0	null
HK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26619
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.28501
DA-10-HD17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.553817
JUND	ENCODE Transcription Factor Targets	1.0	null
GSE183271_2_v_3_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_HEPG2_48H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.47459
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SJXC-0326-SM-2XCFI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.996108
TMEM151B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61916
CRCGN015_HEPG2_48H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.7125
biological regulation	GO Biological Process Annotations 2015	1.0	null
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.953334
Kidney renal clear cell carcinoma_KIRC_TCGA-T7-A92I-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RPS2	Pathway Commons Protein-Protein Interactions	1.0	null
CAOV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.47622
GSE76771_1_v_3_atf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellar cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.974839
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.54754
ZRANB2	Pathway Commons Protein-Protein Interactions	1.0	null
DD-42-PC65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.459668
GSE158182_5_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VPS25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90708
GTEX-PVOW-2626-SM-32PL8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843174
Invertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.998
TMEM50A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14279
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.71285
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.9504
GRINA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37062
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
explanation	GeneRIF Biological Term Annotations	1.0	null
CRCGN010_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.68856
DNAJC9	Pathway Commons Protein-Protein Interactions	1.0	null
POLR3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7035
AIMP1	Pathway Commons Protein-Protein Interactions	1.0	null
BCL3	ENCODE Transcription Factor Targets	1.0	null
MED26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.589
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE171837_0_v_3_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EGR1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GD-46-OD81_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20556
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.99687
CRCGN012_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.94357
RARS	Pathway Commons Protein-Protein Interactions	1.0	null
GSE109140_0_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TOR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97292
496100566_FWM_no dementia_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.05069
MSTO211H	CCLE Cell Line Gene CNV Profiles	1.0	2.09793
TCF12	ENCODE Transcription Factor Targets	1.0	null
GTEX-X62O-0008-SM-46MU5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56771
EIF2S1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58577
CRCGN012_HEPG2_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.27481
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6379364-41598_2018_37489_MOESM2_ESM.xlsx-Sheet2_DESeq_MSC_vs_fibroblast-Unnamed_1_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
GLRX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87308
ZBTB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02947
CDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37921
Sarcoma_SARC_TCGA-DX-A7ER-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.52655
GSE201217_3_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FAM210A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48161
sites	GeneRIF Biological Term Annotations	1.0	null
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.977137
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05741
GTEX-WOFM-0126-SM-3MJFE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06323
CRCGN012_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.3124
C2BBE1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00768
TTF2-22483619-CHIP-SEQ-HELA	ChEA Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7DV-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05433
G3BP2	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H838	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.24176
RIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18347
H3K27ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
metabolic process	GO Biological Process Annotations 2015	1.0	null
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
HIST1H1E	Pathway Commons Protein-Protein Interactions	1.0	null
CB-16-SY72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.306702
GTEX-PVOW-0426-SM-2XCF8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20824
SHF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69478
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09294
ARMCX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7084
ARID3A	ENCODE Transcription Factor Targets	1.0	null
PML_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.84572
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39V-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09704
PMC6379364-41598_2018_37489_MOESM2_ESM.xlsx-Sheet2_DESeq_MSC_vs_fibroblast-DESeq_MSC_vs_fibroblast_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
SKNMC	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61541
E2F4-21247883-LYMPHOBLASTOID-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
MAX::MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0
NANOG	ChEA Transcription Factor Targets	1.0	null
TRIM28	Pathway Commons Protein-Protein Interactions	1.0	null
tRNA (m2G10) methyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.525
DC-51-WE27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.714788
EAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14007
GSE63048_11_v_12_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cytosolic small ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.92
GC-04-UF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.2047
H3K36me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Type II polyketide synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.097
ZNF678	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25597
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PECR	Pathway Commons Protein-Protein Interactions	1.0	null
NDUFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0536
CPHXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63257
GTEX-QDT8-0011-R4A-SM-32PKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.9587
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.063
PFN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72507
CA-48-SW47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.393318
C3orf52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66221
CE-04-OJ56_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.266479
PMC8410083-elife-65574-fig7-data1.xlsx-KLF10_network-Unnamed_25_KLF10	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5113908-pone.0166185.s004.xlsx-Supp_1-Supplementary_Table_1_mRNA_expression_correlates_with_STAT3_phosphorylation_for_1279_genes_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN009_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.3015
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31577
ATP-binding cassette (ABC) transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.022
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.938817
PMC9248879-supp_gr.275831.121_Supplemental_Table_S2.xlsx-TP53-dependent_proteins-GeneName_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE108326_1_v_0_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35828
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
against	GeneRIF Biological Term Annotations	1.0	null
rt1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.837
QPCT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41321
Lung adenocarcinoma_LUAD_TCGA-62-A46P-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.04547
Calu-6	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.90584
CRCGN011_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.46385
GTEX-OHPN-0011-R1A-SM-2I5GB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29171
CRCGN016_MCF10A.TP53.M_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01633
Embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.54778
CRCGN016_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.99718
GSE100732,GSE100733_0_v_1_lrpprc_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KAT2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DDX21	Pathway Commons Protein-Protein Interactions	1.0	null
CHLA57	DepMap CRISPR Gene Dependency	1.0	3.42615
Rectum adenocarcinoma_READ_TCGA-DC-6155-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100370_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.05029
rnf2_20805357_u2os_osteosarcoma_lof_human_gpl570_gse23035	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.015233
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RRP12	Pathway Commons Protein-Protein Interactions	1.0	null
POU2F2	ENCODE Transcription Factor Targets	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.986291
WRAP53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67093
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LRCH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26642
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XV7Q-0926-SM-4BRVQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960874
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.37268
R3HCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27833
ADM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8088
GSE203158_1_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC7A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33131
striatum_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.5267
ENDOU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82452
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A560-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC25A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67744
CRCGN009_HEPG2_24H:H02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.05082
primary auditory cortex (core)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.883719
plastid-encoded plastid RNA polymerase complex B	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.544
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MATN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11247
CAPRIN1	Pathway Commons Protein-Protein Interactions	1.0	null
ACADVL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14868
POLR2AphosphoS5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46169
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.12744
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27354
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-POYW-0006-SM-2XCF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.81175
CRCGN012_HEPG2_24H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.38849
LAGE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66501
GSE249544,GSE249637_6_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DDX3Y	Pathway Commons Protein-Protein Interactions	1.0	null
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	GO Molecular Function Annotations 2025	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TMMY-0626-SM-33HBD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858382
PMC7584566__F5	PFOCR Pathway Figure Associations 2024	1.0	null
TAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92955
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.83611
Lung squamous cell carcinoma_LUSC_TCGA-85-7697-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZMIZ1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Stipule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.674
DAZAP1	Pathway Commons Protein-Protein Interactions	1.0	null
Congenital Contractural Arachnodactyly	DisGeNET Gene-Disease Associations	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LG-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CD-05-PU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.08434
GSE147662_3_v_5_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lb7	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.906
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DH-A669-02A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AH-0826-SM-48TZN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15824
HNRNPA1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23944
WDR35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33564
E2F4_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S3XE-0926-SM-4AD4S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925416
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K36me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YV-0008-SM-4E3HP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03583
SNRPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56577
GTEX-QMR6-0011-R1A-SM-32PKW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1329
cerebellar cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-3.2217
GTF2I	Pathway Commons Protein-Protein Interactions	1.0	null
496100445_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.08116
MYC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBM39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82096
CTCF_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF213	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.0888
TRIM28	ENCODE Transcription Factor Targets	1.0	null
steps	GeneRIF Biological Term Annotations	1.0	null
Intracellular immature spore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.634
Malignant Head And Neck Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
GSE202434,GSE202438_10_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19429
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-0011-R9A-SM-2TF67	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6296
CRCGN014_HEPG2_24H:P01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.38811
Hs-940-T	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.70334
GSE164508_1_v_0_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
DTYMK	Pathway Commons Protein-Protein Interactions	1.0	null
PMC5358377-pnas.1615015114.sd02.xlsx-Sheet1-genes_with_VDR_peaks_with_and_without_D3_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
SP1	ENCODE Transcription Factor Targets	1.0	null
RNF2	ENCODE Transcription Factor Targets	1.0	null
USP39	Pathway Commons Protein-Protein Interactions	1.0	null
NT5C3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95497
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29C-06A-21R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NANOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10087
TC-71	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GAR1	Pathway Commons Protein-Protein Interactions	1.0	null
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8160578-JCB_202009147_TableS4.xlsx-E2F1_targets-Genes_n_1867_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
ZMYM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33856
LSM3	Pathway Commons Protein-Protein Interactions	1.0	null
RDM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59999
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bone marrow	HPA Tissue Protein Expression Profiles	-1.0	-1.78868
KTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91101
Lung adenocarcinoma_LUAD_TCGA-MP-A4TA-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE215351,GSE215794_4_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.58461
SP4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
RPL31	Pathway Commons Protein-Protein Interactions	1.0	null
IC-76-JU42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.955413
enzyme	GeneRIF Biological Term Annotations	1.0	null
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWOO-0826-SM-48TCL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39275
hsa-miR-520g	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-O5YV-1126-SM-3LK73	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05412
ZEB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60683
SRSF5	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-NL3H-0011-R7a-SM-2I3G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17302
CRCGN015_HEPG2_48H:B21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.25098
CRCGN013_HEPG2_24H:P02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.09991
rh30	HPA Cell Line Gene Expression Profiles	-1.0	-1.80223
PK-45P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47095
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A6C6-01A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTF2H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42045
striatum_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06877
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-XPVG-0526-SM-4B65N	GTEx Tissue Sample Gene Expression Profiles	1.0	3.39901
GSE190384,GSE190386_0_v_8_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0273
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain_Germinal_Matrix	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.21604
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.08824
496100432_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01014
EFEMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81305
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4267	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
TMEM205	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98597
E2F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7165
DTX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.6097
LIN28A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60112
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-1.78868
CRCGN017_MCF10A.WT.HP_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5865
HNRNPH3	Pathway Commons Protein-Protein Interactions	1.0	null
CAL-120	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.58633
CRCGN009_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.72554
GNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51573
B-cell chronic lymphocytic leukaemia-small lymphocytic lymphoma_Peripheral blood mononuclear cell_GSE8835	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.13719
PMC10534007-Table_2.xlsx-S2_overlap_MSC_down_B_V-395_common_elements_in_VM-CUB1_MSC_down_and_BFTC905_MSC_down_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
MARCKS	Pathway Commons Protein-Protein Interactions	1.0	null
GSE166920_6_v_4_adalimumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RUSQ-0826-SM-47JWW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31902
GSE195568_1_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FE-10-KQ78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.605096
GTEX-Q2AG-0008-SM-48U2K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18502
PMC7697260__F4	PFOCR Pathway Figure Associations 2023	1.0	null
CRCGN017_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.00615
CHD2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OV7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38102
CRCGN016_MCF10A.TP53.M_24H:B22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.00341
JKAMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35113
SLC52A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49491
GGNBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39014
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_HEPG2_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.72227
ADCY5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21864
GTEX-WYBS-0426-SM-3NM9M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892638
ATOH7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56848
FOXE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39085
PEG3	Pathway Commons Protein-Protein Interactions	1.0	null
SPARC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43192
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
modeling	GeneRIF Biological Term Annotations	1.0	null
PMC3827940-2045-3329-3-12-S1.docx-1-Supplementary_Table_2_Minor_allele_frequencies_MAF_and_p-values_for_comparison_of_genotype_frequencies_Z9001_genotyped_whites_n_273_versus_non-whites_n_58_1_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S4Z8-0008-SM-33HAZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843017
CRCGN015_HEPG2_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.90152
GTEX-OIZI-0526-SM-2XCEG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879864
GSE133213_9_v_15_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
amygdaloid complex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02603
GSE140997_10_v_5_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.51118
ZIC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.356
MYL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57727
SEC62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22297
RASGEF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98537
Brain Lower Grade Glioma_LGG_TCGA-DU-6402-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
documented	GeneRIF Biological Term Annotations	1.0	null
CRCGN010_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.41645
POGZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90425
MRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47498
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.841574
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.1339
GTEX-XYKS-0008-SM-4BRW6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0886
CIART	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7545
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LOXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6972
FOXA1_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149124,GSE149128_2_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBM19	Pathway Commons Protein-Protein Interactions	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.76135
GSE57871_1_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KLC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84727
GSE125862_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
NDUFS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87466
MSH2	Pathway Commons Protein-Protein Interactions	1.0	null
SND1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE57871_1_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE137144_5_v_7_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FLI1	ENCODE Transcription Factor Targets	1.0	null
GABPA_01_191	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	9.99679
EGR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.5687
primary motor cortex (area M1, area 4)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.935465
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-7109-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cerebral ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.668
hsa-miR-16-5p	MiRTarBase microRNA Targets	1.0	null
GSE233647_4_v_6_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
NC-01-ET52_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.209075
PMC3910540-725780.f1.xlsx-Table_S5-MYC_target_genes_in_human_ES_cells_Ji_Wu_et_al_2011_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
MAPK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63748
dorsolateral prefrontal cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02948
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PGGHG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36625
FXYD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68972
PAX5_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S4-Table_S4_The_result_of_MR_analysis_and_sensitivity_analysis_for_IPF_susceptibility_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.25875
TMEM121B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98126
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXP2_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DNA polymerase V complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.096
INF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09865
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65334
primary auditory cortex (core)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.10503
A-Vietnam-1203_CIP048_RG4-2004(H5N1)HAAvirmut_1day-MOI-10^4_None_GSE37572	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.80299
DAGLB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70395
SHOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01083
ZNF524	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7891
GTEX-QVJO-0011-R1A-SM-2S1QI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.72398
GTEX-QMR6-0011-R5A-SM-32PKT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.939874
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20929
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28742
GTEX-S4P3-1826-SM-3K2AL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26368
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09671
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.03802
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.60255
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE119978,GSE180930_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.15255
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PVOW-0008-SM-48TE8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93697
GF-32-FY02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.206717
GTEX-OHPN-0011-R5A-SM-2I5FF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.9725
Brain Lower Grade Glioma_LGG_TCGA-VW-A7QS-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tou	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.527
Sarcoma_SARC_TCGA-MJ-A850-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Parasitic protozoa infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.136
COLO792	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37908
GTEX-QDT8-0426-SM-32PKZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30831
POLR2A_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
codon	GeneRIF Biological Term Annotations	1.0	null
DNA recombinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.896
HKDC1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM10847_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BC-40-TU13_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.321381
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-WFON-1726-SM-4LVMQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941669
NANOG-16153702-HESC-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
SART1	Pathway Commons Protein-Protein Interactions	1.0	null
Plastid ribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.825
PMC8787225-Data_Sheet_1.xlsx-STable_2_DEG-Supplementary_Table_2_1150_up-_and_down-regulated_differential_expressed_genes_upon_GATA2_activation_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN012_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.456
GTEX-SE5C-0008-SM-4B64J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37019
CRCGN016_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.42049
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-7269-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6ES-01A-12R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U3ZM-0526-SM-4DXTB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871924
PMC11668092-12884_2024_7077_MOESM1_ESM.xlsx-Table_S1-Table_S1_Instrumental_variables_used_in_MR_analysis_of_the_association_between_druggable_genes_and_HG_based_on_Finngen_study_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
ENTREP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44102
GTEX-RM2N-1626-SM-2TF5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30677
YD-49-HM53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.237381
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.910412
Acute Myeloid Leukemia_LAML_TCGA-AB-2861-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HC-74-HM63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.367268
eRF1 methyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.52
BAIAP2L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68041
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DA-33-BM26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.264582
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JE-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4PP-0326-SM-33HC4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21083
karpas707	HPA Cell Line Gene Expression Profiles	-1.0	-1.12734
TMF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3159
BCL3	ChEA Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ES-A2HT-01A-12R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMPD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04766
ALG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15988
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KCNJ11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24272
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11502753-41467_2024_53330_MOESM11_ESM.xlsx-Sheet1-SMAD3_target_genes_hES_SMAD3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE137177_1_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-Q2AI-0008-SM-48U2H	GTEx Tissue Sample Gene Expression Profiles	1.0	2.13809
COL8A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47628
496100451_TCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.0465
GABPA_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YTHDF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77265
HCA-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.81786
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-PN-A8MA-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE199255,GSE199356_6_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.881129
MM160113	DepMap CRISPR Gene Dependency	1.0	4.59382
A1CF	Pathway Commons Protein-Protein Interactions	1.0	null
DCLRE1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81953
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A8YI-01A-21R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-MEL-24	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
hs888lu	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.043
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A7VF-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XXEK-1426-SM-4BRW1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853815
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.955193
H4C16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93741
ZNF71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00824
GTEX-O5YT-0226-SM-32PK5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17472
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56011
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MPHOSPH10	Pathway Commons Protein-Protein Interactions	1.0	null
GSE139455_4_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE201270,GSE201272_5_v_1_mybl2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
methylcrotonoyl-CoA carboxylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.344
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.74526
IB-33-TE51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.346658
RSPRY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65604
DDX54	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08808
Bladder Urothelial Carcinoma_BLCA_TCGA-S5-A6DX-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7832
GTEX-R55D-1126-SM-48FEB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02704
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54E-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.43227
CDC5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63376
TRIM45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33965
GTEX-WRHK-1726-SM-3MJFK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25421
GSE210885_5_v_6_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4149371-pone.0105180.s010.xls-NANOG-GENE_NANOG	Rummagene Transcription Factor Associations 2026	1.0	null
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.910412
GF-35-IT27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.43431
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
APTX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87012
LDHA	Pathway Commons Protein-Protein Interactions	1.0	null
Leaf base	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.501
overlap	GeneRIF Biological Term Annotations	1.0	null
NCIH1650	CCLE Cell Line Gene CNV Profiles	1.0	2.05462
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BC-72-DZ30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.234832
ACHE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76667
H3K36me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SC5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44441
GTEX-O5YU-0008-SM-4E3I7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24036
PMC12559107-12035_2025_5221_MOESM1_ESM.xlsx-Supplment_Tab_3-Supplement_Tab_3_The_result_of_MR_analysis_for_SCZ_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8979909-13353_2022_690_MOESM1_ESM.xlsx-ESR1_targets-genes_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
EGR1	ENCODE Transcription Factor Targets	1.0	null
GSE214931_2_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SH3BGRL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32959
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SHANK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40561
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MACF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53115
ATF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16754
GTEX-OHPN-0011-R11A-SM-2I5FM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41917
KMT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22104
SPATS2L	Pathway Commons Protein-Protein Interactions	1.0	null
MSH6	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.34703
MYC_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
breast	HPA Tissue Protein Expression Profiles	-1.0	-0.773434
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.72398
Arsenic	CTD Gene-Chemical Interactions	1.0	null
BYSL	Pathway Commons Protein-Protein Interactions	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
CTCF_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JIMT-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.21803
GTEX-RTLS-0826-SM-2TF5Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37356
GTEX-R3RS-1326-SM-48FE7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59576
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PARP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58461
MD-92-LN15_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.23106
CRCGN012_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.92353
CBX3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6I0-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BB-87-SF89_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.272128
DB-21-FY75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.465551
SP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	106.374
MAPK1IP1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81758
PIDD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25554
MAX_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX2	ChEA Transcription Factor Targets	1.0	null
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39745
SIRT6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
XRCC6	Pathway Commons Protein-Protein Interactions	1.0	null
SRF	ENCODE Transcription Factor Targets	1.0	null
POP5	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VN-A88R-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mitochondrion	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
LARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04288
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pneumonia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.119
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
breast	GeneRIF Biological Term Annotations	1.0	null
NCI-H460	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21637
H3K36me3_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAKI1	DepMap CRISPR Gene Dependency	1.0	3.29011
GTEX-QLQ7-0926-SM-447BC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00076
PAX5_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-622	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
VAT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85994
Adrenocortical carcinoma_ACC_TCGA-OR-A5K5-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FRAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64051
RPS4Y2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-U3ZN-0008-SM-4DXTL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48242
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-64-1677-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-gene_id_x_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.29938
anterior (rostral) cingulate (medial prefrontal) cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.916597
ZC3H11A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2858-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7606598-NIHMS1624889-supplement-1624889_Supp_Tab1-10.xlsx-S8_MR-JTI-genename_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.927075
PTGR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53292
GSE88819_11_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
THAP1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7584566__F5	PFOCR Pathway Figure Associations 2023	1.0	null
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1156
Mycoplasma pneumoniae pneumonia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.245
KA-81-AG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.584161
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.845247
CSDE1	Pathway Commons Protein-Protein Interactions	1.0	null
MYBL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FAM98A	Pathway Commons Protein-Protein Interactions	1.0	null
BT-20	COSMIC Cell Line Gene CNV Profiles	1.0	2.15316
despite	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HELZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55233
FOXM1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF280A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5061
Prostate adenocarcinoma_PRAD_TCGA-YL-A9WH-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE152432_5_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MIER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23395
TMEM250	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5837
CTCFL_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRCA1	ENCODE Transcription Factor Targets	1.0	null
GSE228181_3_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
C2orf15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92296
GTEX-WL46-0011-R9A-SM-3MJFP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.916509
lung	HPA Tissue Protein Expression Profiles	-1.0	-0.979191
C8orf82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35718
GSE213588_8_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
S117	DepMap CRISPR Gene Dependency	1.0	3.15474
TSNAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.70251
EIF4G1	Pathway Commons Protein-Protein Interactions	1.0	null
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.063
HDAC2	ENCODE Transcription Factor Targets	1.0	null
similar	GeneRIF Biological Term Annotations	1.0	null
GSE145323,GSE145324_9_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IL17RB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62731
PDHA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41955
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.092
positive regulation of cellular process	GO Biological Process Annotations 2025	1.0	null
CRCGN010_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.09248
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PACC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39329
H3K36me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2973-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
SMARCB1	ENCODE Transcription Factor Targets	1.0	null
CRCGN017_MCF10A.WT.HP_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2818
SLC1A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02413
SF295	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.7114
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12749419-41598_2025_28826_MOESM3_ESM.xlsx-RFT_iBody3_hexaplicate-Genes_MBD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE168697_0_v_1_wdr6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.999111
GSE171837_3_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE112760,GSE112767_2_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.875647
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
hsa-miR-187	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
HIV_Infected-mDC_None_GSE42058	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.07062
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fulvestrant_homo sapiens_gpl570_gse22533	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TCF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.7044
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Nerve ring	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.735
MAP3K14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45406
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHLHE40_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
IA-LM	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-1.81475
RKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.910412
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPN-0011-R2A-SM-2I5FB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23393
POLR2A_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR2C2	ENCODE Transcription Factor Targets	1.0	null
BICR 31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.99811
LSM2	Pathway Commons Protein-Protein Interactions	1.0	null
KIF2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5208
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
kidney	GTEx Tissue Gene Expression Profiles	1.0	2.15264
C19orf53	Pathway Commons Protein-Protein Interactions	1.0	null
MAP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43065
GSE189336_1_v_0_nitric oxide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CHD4	ENCODE Transcription Factor Targets	1.0	null
GSE88819_5_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPS17	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNRNPU	Pathway Commons Protein-Protein Interactions	1.0	null
GSE157383_0_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PKDCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03562
PMC5072418__F1	PFOCR Pathway Figure Associations 2023	1.0	null
Urethritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.226
Logical memory (delayed recall) in normal cognition	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.61549
GSE240896,GSE240899_3_v_0_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NOVA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99918
RFX5	ENCODE Transcription Factor Targets	1.0	null
STRAP	Pathway Commons Protein-Protein Interactions	1.0	null
496100429_TCx_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.33247
CEBPD_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P44H-0526-SM-2XCF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1517
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A7B0-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SN8G-0008-SM-4DM4X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32126
ventrolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.98236
Kidney Chromophobe_KICH_TCGA-KL-8339-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.992294
ZNF787	Pathway Commons Protein-Protein Interactions	1.0	null
ARRDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69579
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
Mitotic checkpoint complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.247
CRCGN009_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.11382
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
single-stranded DNA-binding protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.888
GSE216043_11_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
kinetics	GeneRIF Biological Term Annotations	1.0	null
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.925798
positive regulation of cell proliferation	GO Biological Process Annotations 2015	1.0	null
NANOG_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF706	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31039
AUH	Pathway Commons Protein-Protein Interactions	1.0	null
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.862779
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.99153
GSE131649_2_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49205
LD-69-ZV56_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.604444
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4VX-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2725
ADD1	Pathway Commons Protein-Protein Interactions	1.0	null
PA-75-VL17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.377613
hepg2	HPA Cell Line Gene Expression Profiles	1.0	1.00538
binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-S32W-0126-SM-4AD61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41424
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3639
PURA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18786
follow	GeneRIF Biological Term Annotations	1.0	null
GTEX-POYW-1126-SM-48TCI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921008
TFPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39306
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KJ-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.5187
TAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49558
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC12179407-MCO2-6-e70261-s004.xlsx-up_TET3-KO_PQ_vs_Cas9_PQ-Unnamed_10_TET3	Rummagene Transcription Factor Associations 2026	1.0	null
TOR2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82032
PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT38_Protein_cis-instrument_MR-eTable_38_Cis-instrument_Mendelian_randomizaion_screen_of_1_901_cortical_proteins_on_lifetime_smoking_behavior_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
SIX5_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NONO	Pathway Commons Protein-Protein Interactions	1.0	null
Metallochaperone complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.705
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5697-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ASF1A	Pathway Commons Protein-Protein Interactions	1.0	null
Efflux pump complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.717
GTEX-S4UY-0426-SM-3K2AF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.942323
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EO-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4470	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A23K-01A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HELA	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.962965
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_30min-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JU-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UMUC16	DepMap CRISPR Gene Dependency	1.0	2.22141
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ribulose bisphosphate carboxylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.93
SNU-719	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.914338
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZC-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chr16_69322792_A_G_b38	GTEx eQTL 2025	1.0	1.6122
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A762-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
splice	GeneRIF Biological Term Annotations	1.0	null
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF148	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	115.507
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5886-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRPF19	Pathway Commons Protein-Protein Interactions	1.0	null
HEY1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7955
Plastid stroma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.774
H3K36me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S32W-0926-SM-4AD5X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37892
GABPA_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DDX3X	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858529
YY1_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRSF2	Pathway Commons Protein-Protein Interactions	1.0	null
EA-18-FP00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.410901
DEF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12338
GSE221633_0_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03231
GTEX-XGQ4-0008-SM-4AT3Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60415
PML_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUN_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE139455_4_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QEG4-0008-SM-48TYZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92002
Lung squamous cell carcinoma_LUSC_TCGA-39-5036-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKUT1	DepMap CRISPR Gene Dependency	1.0	3.19918
JUND_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OBSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40225
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWS6-0426-SM-47JXH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937283
EPB41L2	Pathway Commons Protein-Protein Interactions	1.0	null
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12478272-mmc1.xlsx-Table_S7-Supplementary_Table_7_Proteome-wide_MR_and_sensitivity_analysis_results_using_the_brain_pQTL_dataset_from_Wingo_et_al_1_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
CRCGN015_MCF10A_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.4048
CRCGN014_HEPG2_24H:J15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.92955
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SF3B3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE223008_11_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN009_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.165
TE5	CCLE Cell Line Gene CNV Profiles	1.0	1.33048
496100361_TCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.04804
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCNN1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35832
EEF2K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54366
GSE165174,GSE165175_0_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
colon	GeneRIF Biological Term Annotations	1.0	null
drive	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
SNF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08996
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
MXI1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SFPQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89495
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.927215
SKIC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.79275
FOSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34025
BA-56-QV45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.254007
true	GeneRIF Biological Term Annotations	1.0	null
GTEX-R55E-0006-SM-2TC5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860149
AD-16-HL96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.650151
BCL3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CLDN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93902
ANTXR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21695
GSE145249_0_v_2_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
RRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10328
MCF7	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.11425
GTEX-QMR6-0011-R7A-SM-32PKL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.973498
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SIN3A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56831
E2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58459
EC-00-KR26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.251259
GGCT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32591
LN-405	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.60017
GOSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0652
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
GSE119978,GSE180930_2_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67179
TEK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12688
GUCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4847
GTEX-X4XY-0626-SM-4E3IN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00235
FB-66-UU47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.414712
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CF-65-GU65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.230299
ARFRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13016
SLC25A30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89666
posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1875
ZBTB7A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1878
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31876
JUND_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-W5WG-0002-SM-3NMDN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05262
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2706-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.27955
PML_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
doxorubicin_homo sapiens_gpl6947_gse25741	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CELF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85325
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PPP1R8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23604
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A263-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MI-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.1038
NFYB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE185944_0_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4691-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
TBP_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.70197
KLHL34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94119
SLC39A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69703
SUMF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.70522
GABPA_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fatty acid elongase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.853
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.8662
LBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61896
BACH1	ENCODE Transcription Factor Targets	1.0	null
PMC6756575__F3	PFOCR Pathway Figure Associations 2023	1.0	null
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-8660-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DDX51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06556
HEPG2	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.28285
GSE93309_2_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199921_1_v_0_romidepsin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54041
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67L-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.04956
CRCGN015_HEPG2_48H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.27454
initiation	GeneRIF Biological Term Annotations	1.0	null
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.460417
FB-66-UU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.548188
ERLEC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63428
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-Fay_Heat_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
UBE3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96452
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of biological process	GO Biological Process Annotations 2015	1.0	null
GSE196259_2_v_3_gcm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
showing	GeneRIF Biological Term Annotations	1.0	null
SAPCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47001
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21113
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TE-4	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.36273
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.832732
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
macromolecule modification	GO Biological Process Annotations 2015	1.0	null
YH-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE200352_11_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ATM_knockdown_113_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.78108
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.989801
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TFAM	Pathway Commons Protein-Protein Interactions	1.0	null
GSE203060_0_v_2_kdm4c_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
XRCC5	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5Q6-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7UI-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TPSG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79168
GSE97278,GSE97280_2_v_3_nsd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT38_Protein_cis-instrument_MR-Unnamed_2_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
AKIRIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46594
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.25963
ELK4_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100426_PCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.01351
GABPA_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.50162
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35434
ZDHHC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42194
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22817
NEURL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86636
GTEX-XUJ4-1026-SM-4BOPB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825654
ALKBH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10453
QUINOLONYL-OXAZOLIDINONE ANTIBIOTIC DNV3837	DGIdb Drug Targets 2026	1.0	6.6165
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TACC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42344
POLR2A_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PTBP1	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67S-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.959249
SORBS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87988
CRCGN009_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.7245
GSE113329,GSE113335_2_v_4_taf6l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZBTB24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.8659
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18466
TNFRSF11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87197
GTEX-RU72-0011-R2A-SM-2TF6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0817
ZFAND6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31598
CRCGN015_HEPG2_48H:A14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.25871
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CD-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.41142
NCI-H2347	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.20886
CYP2U1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05524
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BA-77-US35_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.232164
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-R45C-0926-SM-3GAD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.944463
ELK1	ENCODE Transcription Factor Targets	1.0	null
OCIMY5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48141
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.865068
SKMES1	CCLE Cell Line Gene CNV Profiles	1.0	1.39656
RAB14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90802
U2AF1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN017_MCF10A.WT.HP_24H:N22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2783
CNMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02791
GSE202434,GSE202438_9_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE203158_12_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QMR6-1326-SM-32PLB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.932877
LRRC59	Pathway Commons Protein-Protein Interactions	1.0	null
TEAD4	ENCODE Transcription Factor Targets	1.0	null
regulation of cell proliferation	GO Biological Process Annotations 2015	1.0	null
E2F6	ENCODE Transcription Factor Targets	1.0	null
ALCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.662
KLF15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	103.256
PMC12178937-mmc6.xlsx-L_AKAP12_KDvsD_AKAP12_KD_deg_al-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210885_3_v_1_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BE-27-RQ61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.396488
496100421_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.00643
GTEX-UTHO-0726-SM-3GAEN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848949
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IM-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RH28	DepMap CRISPR Gene Dependency	1.0	2.02583
GSE158197_2_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A204	Achilles Cell Line Gene Essentiality Profiles	1.0	1.41321
REST_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3	ENCODE Transcription Factor Targets	1.0	null
HDDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84623
appendices_4c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.18774
MYOG_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCL3-23251550-MUSCLE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
MBD4_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:N19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.08725
peptidyl-amino acid modification	GO Biological Process Annotations 2025	1.0	null
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFG8-0008-SM-4LVN6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08645
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
CDC5L	Pathway Commons Protein-Protein Interactions	1.0	null
HCC1395	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.35081
Psoriasis vulgaris_Skin tissue_GSE6710	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.46183
PMC6337418__F5	PFOCR Pathway Figure Associations 2023	1.0	null
hsa-miR-509-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
H3K36me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZMIZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86025
CRCGN015_MCF10A_48H:I01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5458
TAF1_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15687
Prostate adenocarcinoma_PRAD_TCGA-FC-A6HD-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
phenylalanine-tRNA ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.62
H3K27ac_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9911396-41467_2023_36178_MOESM11_ESM.xlsx-Sheet1-Genes_in_10kb_vicinity_of_ZBTB12_ChIP-seq_peaks_ZBTB12	Rummagene Transcription Factor Associations 2026	1.0	null
JC-06-ED36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.336857
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
LRRC75B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46845
SIN3A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF460	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	136.342
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_HEPG2_48H:B20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0629
CHD4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-0008-SM-4DXT8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06543
Eyestalk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.873
CRCGN010_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1445
hsa-miR-2110	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
CRCGN010_HEPG2_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.37582
PMC6078963-41467_2018_5311_MOESM5_ESM.xlsx-48h_KD_UP_Vs_ATAC-Genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
mitochondrion	GO Cellular Component Annotations 2015	1.0	null
POLR2AphosphoS5_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOTHC	DepMap CRISPR Gene Dependency	1.0	2.10021
DENND4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95117
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
proteasome-activating nucleotidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.779
PCBP1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
GTEX-QESD-0008-SM-447B2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88308
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ascl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.8065
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S14-Table_S14_MR_resluts_of_brain_pQTL_and_cardioembolic_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
NOA1	Pathway Commons Protein-Protein Interactions	1.0	null
TMEM214	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-1258	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
MAZ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.5678
PMC5263239-mmc2.xls-SEM_-_MLL-AF4-Non-spreading_targets_gene_names_2497_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0011-R9A-SM-32QOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.05092
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211474,GSE212779_0_v_1_phf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CHD7	ENCODE Transcription Factor Targets	1.0	null
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.62924
CEP19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61051
GTEX-S7SE-0005-SM-2XCEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62134
G141	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06022
HCFC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
QA-50-YO37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.60349
CRCGN016_MCF10A.TP53.M_24H:F14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.03032
PMC9608343__F1	PFOCR Pathway Figure Associations 2024	1.0	null
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-05A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0309
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.29139
PMC11096100-41588_2024_1714_MOESM3_ESM.xlsx-ST18-Unnamed_1_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DDX1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-V955-0726-SM-3GAFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843242
AJM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83821
GC-04-UF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.390386
CRCGN015_HEPG2_48H:P15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.12971
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8085-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.7809
ventrolateral prefrontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.928662
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.44708
TAF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FNDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88077
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.13541
H3K79me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SKIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08281
GTEX-RWSA-0626-SM-2XCBD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895623
brain_3c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0728
BD-04-NG34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.380861
RNF135	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71105
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
NCI-H1105	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.05495
CREB3L4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0845
HA-E2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29079
Lung squamous cell carcinoma_LUSC_TCGA-77-A5GA-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETS1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	123.962
ELOVL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54013
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.67475
IPC-298	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5C0-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56363
RPL23	Pathway Commons Protein-Protein Interactions	1.0	null
GSE158197_2_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.39706
G protein-coupled receptor heterodimeric complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.54
H3K9me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9008
SUPT5H	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS5_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEXIM1	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF750	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44863
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.852357
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.80583
SP4	ENCODE Transcription Factor Targets	1.0	null
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	GO Molecular Function Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-62-8402-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE206502_2_v_1_igf2bp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7304-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRAME	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09836
MYC_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S341-0526-SM-4AD5U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16901
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Optic ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.878
brain	GTEx Tissue Gene Expression Profiles	-1.0	-1.36898
GTEX-WQUQ-0006-SM-3MJF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49696
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4480	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.82886
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CCDC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49954
BD-69-GX17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.432553
SP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77759
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.14781
ZNF579	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60098
FOSL2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Photosystem II	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.302
Germinated grain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.897
MATCAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5208
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BT-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SE5C-0426-SM-4BRUI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16293
SPI1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SIU8-0008-SM-4BRUC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91443
MET_knockout_248_GDS3148	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.05436
Lung squamous cell carcinoma_LUSC_TCGA-94-7033-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FEN1	Pathway Commons Protein-Protein Interactions	1.0	null
TWF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6385
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.49825
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MICU1	Pathway Commons Protein-Protein Interactions	1.0	null
TCF7L2_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE160246_9_v_5_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6855629-pone.0225186.s009.xlsx-Sheet1-DEGs_downregulated_in_HEK293_MEIS1_KO_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
DPPA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78154
HT144SKINFV2	DepMap CRISPR Gene Dependency	1.0	7.75495
L33	DepMap CRISPR Gene Dependency	1.0	2.07875
nes	HPA Cell Line Gene Expression Profiles	-1.0	-1.57529
RALA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29058
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NELFE_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EF-92-OO68_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.298661
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XMK1-1726-SM-4B64Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06738
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6IH-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KU1919	CCLE Cell Line Gene CNV Profiles	1.0	1.38401
RWDD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45785
GSE216043_11_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
XPO7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58067
KYSE-150	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.29212
CRCGN008_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.0575
ZZZ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77366
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE223008_11_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
protein metabolic process	GO Biological Process Annotations 2015	1.0	null
CRCGN008_HEPG2_24H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.60685
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.929212
FBXL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68605
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
macromolecule biosynthetic process	GO Biological Process Annotations 2015	1.0	null
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN014_HEPG2_24H:B12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.19391
G6PD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87404
SLC41A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.33273
YY1	ENCODE Transcription Factor Targets	1.0	null
GTEX-NL4W-0011-R2a-SM-2I5GV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907877
dorsolateral prefrontal cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.840692
POLR2AphosphoS2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ADAM17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1056
IC-05-AW29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.46557
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IMR32	DepMap CRISPR Gene Dependency	1.0	2.70882
D283MED	CCLE Cell Line Gene CNV Profiles	-1.0	-2.36569
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NALM6	Achilles Cell Line Gene Essentiality Profiles	1.0	1.00354
H1_BMP4_Derived_Mesendoderm_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.17281
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3127
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AL-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05702
EB-67-WB79_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.386175
HLX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98542
GTEX-XBEW-0002-SM-4AT5O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54696
EPRS	Pathway Commons Protein-Protein Interactions	1.0	null
GSE213228_2_v_3_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BE-66-GV20_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.243295
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U7-06A-21R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCDC71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76428
GSE148200_0_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CAMLG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83653
DDX5	Pathway Commons Protein-Protein Interactions	1.0	null
Olfactory glomerulus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.547
SF3A3	Pathway Commons Protein-Protein Interactions	1.0	null
DPF2_02_14	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.5875
RUFY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35245
STK10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67991
ETS1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KATNBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37009
cellular macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
E2F8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4714
NCIH1573	DepMap CRISPR Gene Dependency	1.0	3.70896
GTEX-S33H-0826-SM-4AD5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951126
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C6orf89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44367
CRCGN012_HEPG2_24H:J19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.47655
GTEX-VUSG-0126-SM-4KL1X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02399
CDKN2AIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40793
PMC3466441__F1	PFOCR Pathway Figure Associations 2023	1.0	null
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.16647
SRP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21263
GDM1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.84452
ZFPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98728
TTF2	ChEA Transcription Factor Targets	1.0	null
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNRNPH1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RTLS-0008-SM-48FET	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878331
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29V-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
S-layer	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.573
UFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82697
CD4_Memory_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.922905
GTEX-T2YK-0008-SM-4DM6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39013
DE-34-DT75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.23631
RPS3A	Pathway Commons Protein-Protein Interactions	1.0	null
PHC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51546
496100622_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1656
496100660_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.13182
GSE226316_1_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:I12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.52955
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
reveals	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRL-0008-SM-3NB29	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15256
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.05616
SPI1	ENCODE Transcription Factor Targets	1.0	null
skbr3	HPA Cell Line Gene Expression Profiles	-1.0	-0.98772
ELF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPK5-0008-SM-4IHJD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876549
PA-80-RV09_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.236533
RPL23A	Pathway Commons Protein-Protein Interactions	1.0	null
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
CRCGN015_HEPG2_48H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6152
POLR3A	Pathway Commons Protein-Protein Interactions	1.0	null
ARFGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4014
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XY-0226-SM-4E3IZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35078
GSE199899_3_v_2_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Progression Of Prostate Cancer	DisGeNET Gene-Disease Associations	1.0	null
pdf	GeneRIF Biological Term Annotations	1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8518-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WBSCR22	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A766-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.171
CRCGN013_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.7707
HDLBP	Pathway Commons Protein-Protein Interactions	1.0	null
RAB6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93003
CYP2D6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38298
positive regulation of cell population proliferation	GO Biological Process Annotations 2025	1.0	null
Cytoophidium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.708
CRCGN017_MCF10A.TP53.M_24H:I18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0636
H3K36me3_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBP_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61969
ODF2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15979
Uterine Carcinosarcoma_UCS_TCGA-N7-A4Y0-01A-12R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE153871_1_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Esophageal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.613
CLUH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9172
QARS	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EW-7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DDX17	Pathway Commons Protein-Protein Interactions	1.0	null
ELAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17023
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A3-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
co-translational protein modification	GO Biological Process Annotations 2025	1.0	null
GTEX-OXRP-2526-SM-2S1NO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904914
plastid-encoded plastid RNA polymerase complex A	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.394
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53021
Cell envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.514
testis_7d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.80194
GTEX-NL3H-0011-R5a-SM-2I3GB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30692
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.949235
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02603
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.93035
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-64-1676-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE186647,GSE217288_11_v_7_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U8T8-0008-SM-4DXSP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2351
PMC5575985-mp2016192x4.xlsx-ST18-Unnamed_5_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21749
GTEX-S33H-1626-SM-4AD68	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85855
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A85I-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN014_HEPG2_24H:A03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4541
KDM5B	ENCODE Transcription Factor Targets	1.0	null
PMC12749419-41598_2025_28826_MOESM3_ESM.xlsx-RFT_iBody3_triplicate-Genes_MBD1	Rummagene Transcription Factor Associations 2026	1.0	null
Cell envelope Sec protein transport complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.76
PMC6089552-oncotarget-09-31018-s004.xlsx-compound_targets_chip_rnaseq-Chip-seq_derived_EWS-FLI1_targets_Bilke_et_al_2013_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
confirmed	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-4691-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
CRCGN015_HEPG2_48H:B11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.65885
PPP1R7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16213
CRCGN014_HEPG2_3H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06276
POLR2A_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EXD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17868
UBTF	ENCODE Transcription Factor Targets	1.0	null
NOLC1	Pathway Commons Protein-Protein Interactions	1.0	null
PEX14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0835
CNTRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91419
IDH3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12572
GTEX-PWOO-1326-SM-48TCJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07912
GSE96777,GSE96778_1_v_0_zbtb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RA-27-ST16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.232597
NFATC1	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-934	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
PMC11167905-10194_2024_1805_MOESM1_ESM.xlsx-S6-Table_S6_MR_results_of_brain_eQTLs_and_migraine_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN011_HEPG2_24H:P07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6255
TP53BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38288
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BE-27-RQ61_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.705031
hsa-miR-4279	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GSE203060_0_v_1_kdm4c_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FB-32-PY27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.23901
BA-46-YF32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.302805
NELFB	Pathway Commons Protein-Protein Interactions	1.0	null
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:I04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.46535
GTEX-Q2AI-0426-SM-48U13	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824495
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ELF1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LUC7L2	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN008_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.51875
CRCGN013_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.07839
LGR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36066
H3K14ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RNF103	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03498
CHCHD1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SRSF3	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ELAVL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71096
CRCGN015_HEPG2_48H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.12193
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-548ah	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GTEX-NL3H-0011-R4a-SM-2I3GK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02872
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S15-Table_S15_MR_resluts_of_brain_pQTL_and_small-vessel_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN008_HEPG2_24H:I03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1468
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NR2F2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28443
Brain Lower Grade Glioma_LGG_TCGA-DB-5274-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mitochondrial small ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.543
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CREB1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BE2M17	DepMap CRISPR Gene Dependency	1.0	2.67262
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PRALATREXATE	DGIdb Drug Targets 2026	1.0	2.2055
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S6-Table_S6_The_result_of_MR_analysis_and_sensitivity_analysis_for_DLco_decline_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE153871_4_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Bacteriocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.023
GTEX-T5JW-2026-SM-4DM63	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48107
colonrectum_b	HPA Tissue Sample Gene Expression Profiles	1.0	1.14635
PRRC2A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE155031_5_v_0_dextran_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
PMC9745835-supp_079195.122_Supplemental_Table_1.xlsx-ADAR-KD-Gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-N7MS-1626-SM-3LK5F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23866
RPL22	Pathway Commons Protein-Protein Interactions	1.0	null
RUNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56027
ESS-1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.99947
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6267
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUW1-0008-SM-4BOQH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12172
RPL38	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QCQG-0008-SM-48U2G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07901
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A97G-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PLZ4-1326-SM-2S1O7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.72398
ZBTB14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.395
CRCGN017_MCF10A.WT.HP_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6122
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0153
SMC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08495
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3027
GTEX-X4XY-1726-SM-46MVO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34954
DHX35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67497
FOXF2	JASPAR Predicted Transcription Factor Targets	1.0	null
YY1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.35884
GTEX-RVPU-0011-R9A-SM-3NM8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.72398
UGCG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82489
ERCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80505
SP8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.205
GSE209898,GSE209899_0_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Chelate leg	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.555
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7413
CRCGN012_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5032
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26049
TRIP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19129
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A1NK-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DC-22-OP01_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.219606
BCLAF1	ENCODE Transcription Factor Targets	1.0	null
BA-69-TQ80_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.438271
L-5178-Y cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.814
IGBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63573
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:A18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.16193
CEBPB_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU1J-0008-SM-46MV9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19339
GTF2E2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PBX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ITK_knockout_241_GSE12465	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.93144
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.45604
ALYREF	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-PX3G-0008-SM-48U2L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49357
GTEX-TKQ2-1026-SM-33HB7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.931381
METOPRINE	DGIdb Drug Targets 2026	1.0	2.2055
ZNF846	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5185
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACLY	Pathway Commons Protein-Protein Interactions	1.0	null
GSE131649_6_v_5_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EP300_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30704
GSE84462,GSE84762_0_v_1_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SMARCB1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QV44-0008-SM-447AX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941843
liver	GTEx Tissue Gene Expression Profiles	1.0	1.16572
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TA-34-CK62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.249606
NCI-H1734	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.8545
MAP4	Pathway Commons Protein-Protein Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I0-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LSM14B	Pathway Commons Protein-Protein Interactions	1.0	null
HNF4A	ChEA Transcription Factor Targets	1.0	null
GTEX-XK95-0008-SM-4AT5G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92082
Ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.487
CTNND1	Pathway Commons Protein-Protein Interactions	1.0	null
CDK11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19507
MONOMAC6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43685
GSE122378_0_v_1_carmil3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.03807
GTEX-RU72-0726-SM-46MUW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41577
TRA2B	Pathway Commons Protein-Protein Interactions	1.0	null
GSE131649_6_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GABPA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
where	GeneRIF Biological Term Annotations	1.0	null
NOTCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86416
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20615
GTEX-S4P3-0426-SM-4AD56	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0423
KLF13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.8772
GTEX-NPJ8-0011-R2a-SM-2TC6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43868
TBP_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF7_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S32W-1926-SM-4AD63	GTEx Tissue Sample Gene Expression Profiles	1.0	2.26144
MEGF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71248
plastid-encoded plastid RNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.357
inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06166
GABPA	ENCODE Transcription Factor Targets	1.0	null
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.846782
RECQL	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AQ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PWCY-0226-SM-48TD8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20186
RPS4Y1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40822
CREB1	ENCODE Transcription Factor Targets	1.0	null
CRCGN009_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.10732
YY1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4Z8-0526-SM-4AD4T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66662
METAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06775
Kidney renal papillary cell carcinoma_KIRP_TCGA-KV-A74V-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-7268-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KAT2A	ENCODE Transcription Factor Targets	1.0	null
EXOSC4	Pathway Commons Protein-Protein Interactions	1.0	null
RCOR1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UTHO-0011-R2A-SM-3GIKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.89579
RPS13	Pathway Commons Protein-Protein Interactions	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RM-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKIV2L2	Pathway Commons Protein-Protein Interactions	1.0	null
NCIH510	DepMap CRISPR Gene Dependency	1.0	2.33247
ZIC5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.238
GSE249893_1_v_0_tfam_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SPHK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92048
start	GeneRIF Biological Term Annotations	1.0	null
AD-51-FB60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.296906
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Crown gall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.604
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9885
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB134VI	CCLE Cell Line Gene CNV Profiles	-1.0	-1.84825
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5239
FOSL2	ENCODE Transcription Factor Targets	1.0	null
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MRFAP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18813
CHD7_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_3H:M21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.9506
PUS7	Pathway Commons Protein-Protein Interactions	1.0	null
posteroventral (inferior) parietal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.867579
TCFL5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.7553
POLR2A	ENCODE Transcription Factor Targets	1.0	null
H3K4ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-QDT8-0011-R1A-SM-32PKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.993516
FADS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09092
NFIC_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SDAD1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
RPL36A	Pathway Commons Protein-Protein Interactions	1.0	null
n-terminal protein amino acid modification	GO Biological Process Annotations 2015	1.0	null
MTA3	ENCODE Transcription Factor Targets	1.0	null
CRCGN017_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.82147
H3K36me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Organism form	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Cardiac Arrhythmia	DisGeNET Gene-Phenotype Associations	1.0	null
H3K27ac_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE162739_6_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TCF7L2_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
PAX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7562
intracellular part	GO Cellular Component Annotations 2015	1.0	null
TAMALIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55921
PMC11953390-41598_2025_94761_MOESM1_ESM.xlsx-Table_S3-Table_S3_The_result_of_MR_analysis_and_sensitivity_analysis_for_CKD_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
C11orf96	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17346
CREB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
S100A14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95286
PNMA6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48356
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0068
GTEX-QDVN-1326-SM-48TZ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06344
TNRC6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22434
VPS37A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35111
KHDRBS1	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
formylated	GeneRIF Biological Term Annotations	1.0	null
GSE149075_1_v_4_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.97552
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PSME3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97219
GSE239844_8_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8635809-Table_2.xls-LPS-downregulated-Unnamed_4_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4506-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QV31-0008-SM-447AT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.2822
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEAD4_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VPS26C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44212
Skin Cutaneous Melanoma_SKCM_TCGA-GF-A6C8-06A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZDBF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61645
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.2662
S100A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37387
ZNF740	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.894
Chela	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.556
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-4749-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A2058	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.39947
CENPX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29852
FOS	ENCODE Transcription Factor Targets	1.0	null
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
organic substance biosynthetic process	GO Biological Process Annotations 2015	1.0	null
HNRNPA0	Pathway Commons Protein-Protein Interactions	1.0	null
PDCD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.0363
Nicotine addiction_Ganglioneuroblastoma_GSE11208	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.53575
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18815
ALKAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84992
CRCGN015_MCF10A.WT.HP_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.64439
COQ6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9681
NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.7064
Malaria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
LUC7L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92546
hippocampus (hippocampal formation)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08999
SNAI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35967
STAT1	ENCODE Transcription Factor Targets	1.0	null
GTEX-QVUS-0011-R9A-SM-3GIJA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69481
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.832045
G84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.876476
GSE213588_10_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HOOK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78071
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
overlaps	GeneRIF Biological Term Annotations	1.0	null
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.82787
GSE225218_0_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5402
ALX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61578
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JF-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE201309_4_v_7_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Sarcoma_SARC_TCGA-QQ-A5VC-01A-31R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79506
Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4U1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCAN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04989
EFTUD2	Pathway Commons Protein-Protein Interactions	1.0	null
PIP5K1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26818
CRCGN015_HEPG2_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.033
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA-60-LK14_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.219209
RHBDD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29851
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.04679
GTF2F1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.986999
Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J1-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN008_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.22255
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07266
HACL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30561
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8237
CDK5RAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89486
GALT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62708
Adenoma_Colon_GSE4183	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.29666
CRCGN015_MCF10A.TP53.M_24H:E17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.7489
PMC3607232-mmc1.xls-MLLN_prom_RS411-MLL_prom_RS411_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WHSB-1626-SM-3LK6J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86462
GSE228181_4_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF695	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67286
FE-82-WB22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.717713
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-RUSQ-0526-SM-2TF72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.11502
CRCGN008_HEPG2_24H:G17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.78765
AGRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95411
iron-sulfur cluster assembly complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.162
PMC4801062__F3	PFOCR Pathway Figure Associations 2024	1.0	null
SIN3A_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZXDB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51905
H2AC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8066
Pheochromocytoma and Paraganglioma_PCPG_TCGA-XG-A823-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TADA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40553
GTEX-OIZG-0008-SM-4E3J2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23878
RBMX	Pathway Commons Protein-Protein Interactions	1.0	null
TBC1D10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70554
GSE118766_2_v_0_ifng_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HslUV protease complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.106
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USP7	Pathway Commons Protein-Protein Interactions	1.0	null
GSE224547_1_v_0_cftr_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K79me2_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.579684
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRO-0011-R10A-SM-2I5EH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15116
496100648_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.05244
ME-31-RM40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.221038
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A_48H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2091
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5881-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TENT4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06558
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7PM-0008-SM-3NM9Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56179
GSE131649_2_v_3_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFON-1926-SM-3LK7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00175
AB-33-EM56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.21505
MYC_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.4583
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPL35	Pathway Commons Protein-Protein Interactions	1.0	null
GSE200388_0_v_1_gemin5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE157296,GSE157298_4_v_5_kbtbd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S5-Table_S5_The_result_of_MR_analysis_and_sensitivity_analysis_for_FVC_decline_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
SW1783	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.6088
GTEX-U3ZH-0926-SM-4DXU4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937833
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
U2AF2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-S4UY-0008-SM-3NM8H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978356
TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9247
GTEX-S95S-0008-SM-4AT5M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832771
POLI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35047
GSE139455_7_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
S0-EE-Y4UM_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214987
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13365
SMU1	Pathway Commons Protein-Protein Interactions	1.0	null
HCFC1	ENCODE Transcription Factor Targets	1.0	null
GTEX-XMK1-0226-SM-4B65D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33702
GTEX-QDT8-0011-R5A-SM-32PKN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28414
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
only	GeneRIF Biological Term Annotations	1.0	null
GSE213228_1_v_3_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CNN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90845
GTEX-XYKS-0926-SM-4BRVG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0453
EGR1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETS1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.7974
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
496100505_TCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.78828
HT144	DepMap CRISPR Gene Dependency	1.0	4.54536
GTEX-WFG7-0008-SM-4LMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09475
GSE213588_8_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE203158_5_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Middle lamella	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.564
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157F_vs_MSX1-Gene_id_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE185519_4_v_5_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-95-7043-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPINT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50476
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TIFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24654
GSE192771_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Placenta	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
POLR2A_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JE-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8481886-Table_1.xlsx-A_subsets-iMSC_fetal_MSC_UC_MSC_bone_marrow_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
PSRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48982
GTEX-OHPN-0011-R3A-SM-2I5FC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.72398
CRCGN016_MCF10A.WT.HP_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.74105
SYNCRIP	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A48D-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SSB	Pathway Commons Protein-Protein Interactions	1.0	null
MARS	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN008_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.97785
stomach	HPA Tissue Gene Expression Profiles	1.0	0.862619
CRCGN017_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4094
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21722
Heterocyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.648
TEAD4_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Polyketide synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.34
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KCL-22	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-4.12547
KIFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50637
GTEX-PWO3-0011-R2A-SM-2S1OX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47297
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.948102
ITGA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12587
cancers	GeneRIF Biological Term Annotations	1.0	null
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRACR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02303
CRCGN008_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.4071
MED14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73641
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.31478
Urease complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.984
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.899968
CRCGN016_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.34783
EE-98-PF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.388598
GSE151782_4_v_5_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-P44H-0011-R8A-SM-2XCEL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850443
EPN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20435
GSE110440_1_v_0_rad21_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN010_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.68173
ZNF138	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06558
SKBR3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.72878
PES1	Pathway Commons Protein-Protein Interactions	1.0	null
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9181
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EIF3F	Pathway Commons Protein-Protein Interactions	1.0	null
KPNB1	Pathway Commons Protein-Protein Interactions	1.0	null
NOP9	Pathway Commons Protein-Protein Interactions	1.0	null
GSE165548_2_v_8_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE244072_10_v_3_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59535
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
spleen	HPA Tissue Protein Expression Profiles	-1.0	-0.979191
SHOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15622
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08863
PAPLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44493
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH2030	CCLE Cell Line Gene CNV Profiles	1.0	1.84969
HNRNPAB	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A657-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EP300_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6369-01A-21R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tonsil_8b1	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.85836
FOXA1	ENCODE Transcription Factor Targets	1.0	null
ZNF778	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91033
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A6I1-01A-12R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8143797-elife-62857-fig3-data2.xlsx-DEgenes_SW872_TAZ-CAMTA1_vs_EV-Gene_CAMTA1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XYKS-0002-SM-4BRWN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2474
GTEX-QVUS-2926-SM-3GIJB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.992332
496100330_PCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.04725
GSE200673,GSE200691_2_v_3_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A1-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157F_vs_MSX1-Gene_name_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF514	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02244
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE139455_4_v_1_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN013_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.05764
CRCGN017_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.53603
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-6594-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AW-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TP53_01_286	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.58836
GSE185944_5_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RFC4	Pathway Commons Protein-Protein Interactions	1.0	null
KLF5	JASPAR Predicted Transcription Factor Targets	1.0	null
NatB complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.32
SNRPB2	Pathway Commons Protein-Protein Interactions	1.0	null
MRPS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55971
MYC_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cytoplasmic exosome (RNase complex)	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.872
ZNF343	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.2687
FGF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02616
SNU13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8138
ovary_8a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.25798
PLD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16858
NCIH838	CCLE Cell Line Gene CNV Profiles	1.0	1.68061
GTEX-WCDI-0008-SM-47JYE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91386
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
transition metal ion binding	GO Molecular Function Annotations 2015	1.0	null
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
pockets	GeneRIF Biological Term Annotations	1.0	null
LGALS3BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87177
MAX_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GA-88-CF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215808
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5386
KLF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65296
Methemoglobinemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.01
PBX3	ENCODE Transcription Factor Targets	1.0	null
MAFA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.2918
GTEX-T5JC-0008-SM-4DM6A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92622
USF2	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61G-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
INO80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73858
EE-98-PF86_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.326841
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.08185
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.58461
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN012_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.82847
gata1_15860665_megakaryocytes_lof_mouse_gpl1261_gds1245	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.385566
CRCGN016_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.91572
LRPPRC	Pathway Commons Protein-Protein Interactions	1.0	null
MRPL52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06382
POLR2A_GM18526_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_3H:E07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.45805
b19	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.62
RPS11	Pathway Commons Protein-Protein Interactions	1.0	null
GSE199092_3_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TARBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57594
MYC_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00369
MM426	DepMap CRISPR Gene Dependency	1.0	2.72255
H3K36me3_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
first	GeneRIF Biological Term Annotations	1.0	null
KA-81-AG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.312479
POLR2H	Pathway Commons Protein-Protein Interactions	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3HZ-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.977438
GTEX-WFJO-1026-SM-3GIKL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02106
POU2F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88771
ZEB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Squamous Cell Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
GTEX-XOTO-0011-R9A-SM-4GICI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12828
GTEX-TML8-0008-SM-4DXUI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53412
TMX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70805
GSE166169_0_v_3_elp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Alzheimer Disease	DisGeNET Gene-Disease Associations	1.0	null
GSE213588_8_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
YY1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPS18	Pathway Commons Protein-Protein Interactions	1.0	null
JD-44-KF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.236859
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CPSF2	Pathway Commons Protein-Protein Interactions	1.0	null
CREM-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
NRF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UTHO-0011-R11A-SM-3GIJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18046
ARID3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4476
GTEX-UTHO-0011-R4A-SM-3GIJP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71481
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65874
RAMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21296
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SW620	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.19925
GTEX-QLQW-0226-SM-447BJ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.61368
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05433
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
DAUDI cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.593
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
peptide	GeneRIF Biological Term Annotations	1.0	null
ATIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56334
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.81952
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.52587
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mature B-cell neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.001
NIPSNAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96275
HIST1H4F	Pathway Commons Protein-Protein Interactions	1.0	null
PYCR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01503
DGCR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.321
GSE203158_12_v_14_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN009_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6459
Sennetsu fever	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.62
SYPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70853
GTEX-RWSA-1426-SM-47JXA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960028
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HC-18-NB46_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.234014
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14848
GSE140997_4_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2986-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE240027,GSE240030_5_v_2_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
antisense	GeneRIF Biological Term Annotations	1.0	null
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12628
CHMP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28634
CRCGN009_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.44924
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN008_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.67335
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.685388
KA-75-LP02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.326223
HT-1080	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.8337
GSE241036_0_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
EN	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-4.2342
ADCY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81167
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TGBC24TKB	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.23331
PUR1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE199255,GSE199356_6_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NAPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03538
GSE118766_1_v_0_ifng_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
REST	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	105.489
GSE237040_0_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100526_TCx_dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.05184
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42477
GTEX-QMRM-0008-SM-447B1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.9356
ZBTB33_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:L02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.69539
GTEX-V955-2026-SM-3GAFA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.913839
GSE157894_2_v_0_cystine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Plastid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.004
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.863766
FOXP2_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-W5X1-0526-SM-3GILH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838798
PTF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49132
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.733446
ATRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02826
TMED9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85557
GSE239844_8_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE114690_2_v_0_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN013_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.17575
H3K79me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Foxn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.3832
A-CA-04-2009(H1N1)_4day-RIPK3KO_None_GSE51526	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.41171
TMC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2984
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.882143
Gli2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.4603
Zfp961	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.2842
PITRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76867
POLR2A_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RM2N-1926-SM-48FCU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15999
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06824
GTEX-T6MO-0008-SM-4DM6T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28438
A704	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.12647
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20538
primary auditory cortex (core)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04898
GTEX-XMK1-1026-SM-4B65H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915569
BCL2L12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30589
USF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.74356
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.854281
GD-79-TW34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.239175
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-94-7557-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Endopeptidase Clp complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.458
EWSR1	Pathway Commons Protein-Protein Interactions	1.0	null
LSM6	Pathway Commons Protein-Protein Interactions	1.0	null
CF-91-JY05_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.337792
amygdaloid complex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.922182
SUZ12	ENCODE Transcription Factor Targets	1.0	null
CTCF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TDRKH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01408
MET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99182
TRMT112	Pathway Commons Protein-Protein Interactions	1.0	null
GSE133516_0_v_1_kat7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TKQ2-1726-SM-4DXUP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18273
CRCGN015_MCF10A.TP53.M_24H:F22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.9802
RBM39	Pathway Commons Protein-Protein Interactions	1.0	null
SOCS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0452
NALM-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FD-91-OK66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.585454
H3K36me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE102505_4_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ATF3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NatC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.035
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06166
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MT-0011-R4a-SM-2I3G9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40377
CCNT2	ENCODE Transcription Factor Targets	1.0	null
GTEX-QVUS-0011-R4A-SM-3GAE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.925199
FOXM1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ1-0008-SM-4DXSO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05768
LRRC75A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42719
GB-73-QS80_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.394178
mc2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.793
ELF1	ENCODE Transcription Factor Targets	1.0	null
GSE190534,GSE190536_0_v_3_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.988766
496100418_TCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.53196
icSARS CoV_48Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	0.784584
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SETDB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF200	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56968
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DYNLT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39557
P4HB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09887
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE160817_2_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XXEK-1126-SM-4BRUX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71338
GTEX-OXRK-0826-SM-2HMK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90274
ILF2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE148200_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KLF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32199
UO-31 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.161
GSE213588_10_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RORA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2472
Body wall muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.137
H3K18ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_GM12864_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149903_0_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NAA38	Pathway Commons Protein-Protein Interactions	1.0	null
primary auditory cortex (core)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.22918
GTEX-T2IS-2226-SM-4DM65	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20707
POU2F2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
STAT5A	ENCODE Transcription Factor Targets	1.0	null
GTEX-QDVN-0008-SM-48U2D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941688
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
THRAP3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE215351,GSE215794_4_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN009_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01205
CENPW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82464
BD-49-MD69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.485032
ZNF93	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	151.022
Lung adenocarcinoma_LUAD_TCGA-97-A4M3-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE196110_1_v_2_ndrg3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.49187
ISHIKAWAHERAKLIO02ER	DepMap CRISPR Gene Dependency	1.0	2.68908
SPTY2D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81933
TMEM168	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.966
GSE149139_1_v_0_carm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ESR1	ENCODE Transcription Factor Targets	1.0	null
REST_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPS3	Pathway Commons Protein-Protein Interactions	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H2-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_GM12891_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78M-01A-21R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ADAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21504
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18815
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6D8-01A-31R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH660	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.07824
H3K36me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
CRCGN008_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.12095
GSE242647_2_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Obesity_Muscle - Striated (Skeletal) (MMHCC)_GSE5109	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.39119
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.863766
MEPROBAMATE	DGIdb Drug Targets 2026	1.0	0.367583
GSE118077_7_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
heart	GTEx Tissue Gene Expression Profiles	-1.0	-1.17505
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.9153
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EMG1	Pathway Commons Protein-Protein Interactions	1.0	null
HSPA1B	Pathway Commons Protein-Protein Interactions	1.0	null
Chloroplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.661
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWOO-2426-SM-2S1OV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37525
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0713
ZMPSTE24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0245
CTCF_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JW-0326-SM-4DM6J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.959871
ZNF440	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33234
GTEX-NPJ7-0011-R6a-SM-2I3G7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.825904
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.2526
GSE149264,GSE149267_2_v_1_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SNU-719	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.18472
OVMIU	DepMap CRISPR Gene Dependency	1.0	2.50877
RBM12	Pathway Commons Protein-Protein Interactions	1.0	null
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04868
EBC-1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.93519
Adult_Liver	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.830095
Lung adenocarcinoma_LUAD_TCGA-78-8640-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARL6IP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37262
Hs-578Bst cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.588
CRCGN011_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.36695
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RVPU-0011-R3A-SM-2XCAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.924932
DEGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16841
ZNF326	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33991
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.102
GSE149903_3_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HE-80-BQ08_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.564516
ZNF716	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.04701
EIF2S2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RNOR-0011-R9A-SM-2TF52	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.90022
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.27249
RPL17	Pathway Commons Protein-Protein Interactions	1.0	null
GSE213228_2_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-02A-21R-A36H-07,TCGA-DU-6404-02B-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4FB-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YD-49-HM53_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.767527
KARS	Pathway Commons Protein-Protein Interactions	1.0	null
PMC7217064-IJC-146-3354-s004.xlsx-Table_S5-Supplementary_Table_S5_Genes_significantly_upregulated_in_OC2-transfected_AGS_cell_compared_to_control_ONECUT2	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VWA5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81596
RCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44917
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4QS-1126-SM-3NMD5	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08309
MINK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61536
MAN2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1194
OC-10-FB51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.384306
GSE231641_0_v_1_robo1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN013_HEPG2_24H:B13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.10256
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.954017
YTHDF2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-SN8G-0526-SM-32PLE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23219
GSE181003_1_v_2_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.75196
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
HNF4A	ENCODE Transcription Factor Targets	1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.910412
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
appendix	HPA Tissue Gene Expression Profiles	-1.0	-2.05375
BF-29-LU75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.331868
RNF170	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.71153
Mitochondrial intermembrane space protein transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.641
GSE201309_4_v_8_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE149903_0_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.72398
ID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72364
OCIAML5	Achilles Cell Line Gene Essentiality Profiles	1.0	1.38462
CRCGN015_MCF10A.TP53.M_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.4575
GTEX-U4B1-0826-SM-4DXTW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16729
GTEX-XXEK-0326-SM-4BRVV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61285
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MP-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Middle midgut	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.815
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.3553
GTEX-U3ZG-0001-SM-47JYF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21016
TAF7	ENCODE Transcription Factor Targets	1.0	null
PNPLA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9134
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UTHO-0011-R5A-SM-3GIJD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12222
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
cog8pdf	GeneRIF Biological Term Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-71-6725-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RELA_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5175-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99566
OPM2	Achilles Cell Line Gene Essentiality Profiles	1.0	1.34383
GTEX-RU72-0011-R5A-SM-2TF6U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901775
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TSE9-0011-R7A-SM-3DB7P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08539
F36P	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71207
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A1-11A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.321
STX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01859
HDAC2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WYBS-1226-SM-3NM9N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20144
DHODH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05932
RNF141	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27533
SENP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86847
EZH2	ENCODE Transcription Factor Targets	1.0	null
GTEX-WY7C-2826-SM-3NB3Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.910936
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-7138-01A-41R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.269974
BCLAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE206870,GSE206872_1_v_5_ascl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5797
SRSF4_02_12	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.88583
TAF1_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 900	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.39805
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
F2RL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36343
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE241036_0_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CPSF1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN009_HEPG2_24H:F19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.79195
NCI-H1048	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.95426
NR2F2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVN-0826-SM-48TZ2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29173
ASPH	Pathway Commons Protein-Protein Interactions	1.0	null
C3A	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	3.3153
FOXA2	ENCODE Transcription Factor Targets	1.0	null
Honey	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.678
RRP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32243
TCF3	ENCODE Transcription Factor Targets	1.0	null
CRCGN015_MCF10A_48H:A07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.03457
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	3.06625
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K36me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PTAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5048
GSE84462,GSE84762_0_v_7_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S12-Table_S12_MR_resluts_of_brain_pQTL_and_any_ischemic_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Ewing's sarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.63
XRN2	Pathway Commons Protein-Protein Interactions	1.0	null
MDA-MB-361	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	3.19415
BID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18601
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TJ-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PTP4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81906
Eosinophilia	DisGeNET Gene-Disease Associations	1.0	null
ZC3H4	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.976913
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.3093
RTN4IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88166
GSE149621_3_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3ac_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
IRF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RM2N-0008-SM-48FF3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26375
PRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45699
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
transcription	GeneRIF Biological Term Annotations	1.0	null
ATPase dependent transmembrane transport complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.922
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RELA_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE103124_1_v_0_bmpr1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CEBPB_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDT8-3026-SM-32PKB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02013
CRCGN017_MCF10A.WT.HP_24H:G11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.41055
adrenal gland	GTEx Tissue Gene Expression Profiles	1.0	0.896105
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73777
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.45301
GSE149903_5_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C2orf49	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.874395
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39567
CRCGN015_HEPG2_48H:I07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.90403
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.56857
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00213
GTEX-XXEK-1726-SM-4BRVB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.512
SPI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EHHADH	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN015_HEPG2_48H:E16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.92479
GTEX-PLZ6-0008-SM-48TD5	GTEx Tissue Sample Gene Expression Profiles	1.0	2.60841
Urethral disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.025
SOHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0904
PAM complex, Tim23 associated import motor	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.699
2-[(Formyl-Hydroxy-Amino)-Methyl]-Heptanoic Acid [1-(2-Hydroxymethyl-Pyrrolidine-1-Carbonyl)-2-Methyl-Propyl]-Amide	DrugBank Drug Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7166-01A-12R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE241701_4_v_3_daxx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AN-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN011_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.6118
GTEX-XV7Q-0426-SM-4BRVN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970787
GATA1_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XXEK-0626-SM-4BRWE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04385
ATF2	ENCODE Transcription Factor Targets	1.0	null
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91817
SRF_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
several	GeneRIF Biological Term Annotations	1.0	null
UBTF_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XAJ8-0826-SM-47JY6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841972
YY1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJMC-0008-SM-4IHKK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97169
POLR2A_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF587	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0891
GTEX-PWCY-0008-SM-48TE9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48503
Reticulate body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.773
PCNX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41109
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.02228
GABPA_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
peptidyl-methionine modification	GO Biological Process Annotations 2015	1.0	null
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QLQ7-0008-SM-447AW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12449
hsa-miR-4652-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
AB-18-YN11_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.500951
H3K9ac_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HMBS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10596
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.052
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of villous mesenchyme_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DDX18	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
STARD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72068
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.47195
POLR2AphosphoS5_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UMUC9	DepMap CRISPR Gene Dependency	1.0	4.45526
CRCGN012_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.10344
GSE228413_0_v_3_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
SRP9	Pathway Commons Protein-Protein Interactions	1.0	null
ATM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67878
Proplastid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.595
PMC6400843-Table_5.xls-C_FOXM1_Correlated_genes-Symbol_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_HEPG2_48H:M22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01643
EF-52-ML96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.325182
PROGUANIL	DGIdb Drug Targets 2026	1.0	3.30825
SIN3A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Chlamydia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.185
kidney	HPA Tissue Gene Expression Profiles	1.0	2.04274
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A4DS-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CLINT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78567
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.88278
HNF4A-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rbm15_22490678_hematopoietic_stem_cell_lof_mouse_gpl8321_gds4315	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.065766
GTEX-OHPM-0326-SM-33HCA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2501
SLC25A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56754
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05853
ZNF354C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33716
Kidney renal papillary cell carcinoma_KIRP_TCGA-PJ-A5Z9-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE88819_11_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2211
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UPK5-2026-SM-4JBIM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1269
NCI-H2810	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.82793
GSE93309_2_v_0_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TCEA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09281
cellular process	GO Biological Process Annotations 2015	1.0	null
DCUN1D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.54025
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14536
STAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54043
PTBP1_02_131	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.04963
GTEX-Q2AG-0011-R9A-SM-2HMJ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.987701
NFU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46613
GTEX-S7PM-0011-R5A-SM-3NM8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10514
GTEX-TSE9-1226-SM-4DXTM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868128
GSE226114,GSE226116_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TMEM249	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78058
NFATC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03076
CD-16-KY17_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.255179
MCM5	Pathway Commons Protein-Protein Interactions	1.0	null
Bacterial degradosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.676
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fat_a.V1	HPA Tissue Sample Gene Expression Profiles	1.0	1.19377
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.878
Burkitt lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.111
ABCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57807
GTEX-UPIC-1126-SM-4IHLO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.25633
GSE207135_1_v_0_sod2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58884
GTEX-PWCY-1026-SM-48TD4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00507
PVRIG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41553
NELFE	ENCODE Transcription Factor Targets	1.0	null
GTEX-NL3G-0008-SM-4E3JX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856536
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.02457
MARCKSL1	Pathway Commons Protein-Protein Interactions	1.0	null
oxaliplatin	CTD Gene-Chemical Interactions	1.0	null
GSE186810,GSE186813_7_v_0_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
S100PBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06672
CRCGN016_MCF10A.WT.HP_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.57284
Brain Lower Grade Glioma_LGG_TCGA-FG-6692-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ABHD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92412
MTFP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46388
FOXA2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36302
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF710	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7631
SNX17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41191
hsa-miR-346	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
E2F4	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7325-01B-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
S117	CCLE Cell Line Gene CNV Profiles	1.0	1.47091
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.978119
ED-11-BL19_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.224788
N-terminal protein amino acid modification	GO Biological Process Annotations 2025	1.0	null
USP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26617
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63227
CRCGN015_HEPG2_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.24257
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.81104
ATF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2154
Attachment organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.815
NALM-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11117
MOV10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.80999
NCI-H2369	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.3827
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11668092-12884_2024_7077_MOESM1_ESM.xlsx-Table_S2-Table_S2_Full_result_of_MR_estimates_for_the_association_between_druggable_genes_and_HG_based_on_Finngen_study_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.955632
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.23076
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A7ET-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.03441
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.35403
ZNF549	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.3443
TTYH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64705
GTEX-R53T-0226-SM-48FEH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0715
CRCGN015_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.27315
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
LRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84591
SEMA3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75669
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNRNPA1	Pathway Commons Protein-Protein Interactions	1.0	null
LEMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42314
FU97	CCLE Cell Line Gene CNV Profiles	1.0	1.33261
ZNF746	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15254
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57253
AB-33-EM56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.530948
FYN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25731
GTEX-W5WG-1126-SM-4LMK4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06991
CRCGN009_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.85552
PMC3607232-mmc1.xls-MLLN_prom_RS411-MLL_body_RS411_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE119978,GSE180930_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.37936
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CPSF6	Pathway Commons Protein-Protein Interactions	1.0	null
PABPN1	Pathway Commons Protein-Protein Interactions	1.0	null
TACO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50149
VD-88-MW70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.991994
GSE166536_3_v_2_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
EPHX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14487
KANK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09696
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PVOW-0626-SM-2XCF6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10893
ZMYND19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99101
NCIH1793	CCLE Cell Line Gene CNV Profiles	1.0	2.42656
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73G-01A-22R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7SF-0008-SM-3NM8T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04497
GTEX-T2IS-0126-SM-4DM6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47412
TAF1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38742
ELK1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.866384
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30516
Mitochondrial degradosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.513
GTEX-SNMC-0008-SM-4DM5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53302
H3K4me1_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5606
EmrE multidrug transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.521
CRCGN011_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.92355
PLC/PRF/5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.18344
PPP2R5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48554
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71119
GSE57871_8_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Eukaryotic translation initiation factor 2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.125
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-T2-A6WZ-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Gametocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.86
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SIN3A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:L23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4202
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DB-41-IH69_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.40278
PAIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35661
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Uterine leiomyoma_Uterus_GSE2725	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	3.26833
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IO-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K36me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWO3-0926-SM-2I5EY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.88795
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ABTB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98082
GTEX-N7MS-0011-R4a-SM-2HMKW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843161
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SU-DHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57228
VAC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53464
DLG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84113
API5	Pathway Commons Protein-Protein Interactions	1.0	null
Tuberculosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.98516
GRIPAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53713
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.86955
LAD1	Pathway Commons Protein-Protein Interactions	1.0	null
NEIL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8532
GSE219274,GSE219276_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CSRNP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31491
GSE234514,GSE234516_1_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4866-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
3-methylcrotonyl-CoA carboxylase complex, mitochondrial	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.478
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RNF168	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59497
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
YY1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWOO-0326-SM-48TDB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835804
MRPL36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49453
RPS7	Pathway Commons Protein-Protein Interactions	1.0	null
EGR3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	84.7893
MYBL2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE57871_1_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POU2F2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE196671_6_v_8_obox4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.74293
PMC7606598-NIHMS1624889-supplement-1624889_Supp_Tab1-10.xlsx-S8_MR-JTI-geneid_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
NMRAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7098
ADD3	Pathway Commons Protein-Protein Interactions	1.0	null
CENPQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61596
GTEX-NPJ7-1326-SM-3MJHO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.975654
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.890913
UNC50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39924
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.83218
STAU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86138
LS 174T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01713
VB-89-RG34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.38862
liver_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.06454
REL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28278
TAF1_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5037-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
GTEx Colon 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-19.9031
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRIM25	Pathway Commons Protein-Protein Interactions	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4W-01A-12R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCFC1_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PADI4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20511
Bipolar Disorder_Lymphocyte_GSE7036	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.10131
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.837636
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-Row_names_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
STAT5A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SSTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54769
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.971471
PMC6400843-Table_5.xls-C_FOXM1_Correlated_genes-Ensembl_ID_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28505
BTBD18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.71501
hsa-miR-4418	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
NRXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56113
BST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82319
FN1	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A5PC-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NGDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13877
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NatA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.134
GTEX-QDVN-1626-SM-48TZC	GTEx Tissue Sample Gene Expression Profiles	1.0	3.64922
GTEX-OXRO-0011-R2A-SM-3NB1W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04125
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPS6	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-PX3G-0826-SM-48TZS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2962
GTF2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-QQ-A5V2-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EGR4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.0076
Sarcoma_SARC_TCGA-DX-A8BZ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HDAC1	ENCODE Transcription Factor Targets	1.0	null
SRSF6	Pathway Commons Protein-Protein Interactions	1.0	null
RTN4RL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36192
ELF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VJYA-1326-SM-3GIJC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24609
SJSA1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.49422
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.25749
GTEX-OXRO-0011-R9A-SM-3NB1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15001
ZBTB33	ENCODE Transcription Factor Targets	1.0	null
SNU1272	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45629
Kidney Chromophobe_KICH_TCGA-KL-8329-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE186810,GSE186813_7_v_0_furin_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10592607-media-2.xlsx-Table_S9-Table_S9_Replication_of_SCZ_risk_genes_by_two-sample_MR_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-UTHO-1026-SM-3GAF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16844
GTEX-XQ3S-0008-SM-4GIDZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02141
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.4307
ARTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01491
ELF1_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTHFD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24669
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.011
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26355
CRCGN015_HEPG2_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.68665
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
OV7	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.23491
GTEX-X4XY-0926-SM-4E3JD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44721
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6I0-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-N7MS-0008-SM-4E3JI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875275
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF397	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52813
SP4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6909-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7812
PMC7697260__F3	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-PLZ5-0326-SM-3P614	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06987
CRCGN017_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.18691
TCF12_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE140997_4_v_3_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U3ZH-1926-SM-4DXTR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973213
PMC5263239-mmc2.xls-SEM_siMLL-AF4-MLL-AF4_gene_targets_significantly_downregulated_739_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-POMQ-0008-SM-48TE7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31042
TCF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16163
ZNF628	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40601
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61371
km3	HPA Cell Line Gene Expression Profiles	1.0	1.19234
ZNF497	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92643
GTEX-XUJ4-2026-SM-4BOOW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2229
TAF7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IBA57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38436
hsa-miR-1224-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GSE244072_10_v_1_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ERF::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.771
DKC1	Pathway Commons Protein-Protein Interactions	1.0	null
NFYA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.71682
FASTKD2	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AY-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.WT.HP_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.11281
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DGUOK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49457
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.952235
GTEX-WEY5-2126-SM-3GILK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.883105
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MSL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51117
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF345	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91327
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51K-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.52834
H3K79me2_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC5263239-mmc2.xls-MV4_11_-_MLL-AF4-Non-spreading_targets_gene_names_1985_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
IKZF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20232
HS 852.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.36103
GSE151782_4_v_7_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GI-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-IW-A3M5-01A-22R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
small intestine	HPA Tissue Protein Expression Profiles	1.0	1.93179
PIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75782
SAP30	ENCODE Transcription Factor Targets	1.0	null
GSE248858_5_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9108619-EMBJ-41-e109191-s016.xlsx-UPF3A_KO_14_3B_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14273
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cysteine synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.634
Nrf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	59.7968
Adrenocortical carcinoma_ACC_TCGA-OR-A5JP-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MN-0011-R4A-SM-32QPG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18939
PDAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25968
GTEX-R53T-1626-SM-3GAEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.980288
ENOSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64729
LS513	Achilles Cell Line Gene Essentiality Profiles	1.0	2.56382
GTEX-W5WG-0008-SM-4KL25	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35824
CRCGN009_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6517
PRSS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20176
CREBBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55071
GTEX-P78B-0008-SM-48TE1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886794
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963727
GTEX-P4QT-0008-SM-48TDZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952696
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PYGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11744
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38121
PMC4149371-pone.0105180.s010.xls-SOX2-GENE_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G3BP1	Pathway Commons Protein-Protein Interactions	1.0	null
RSL1D1	Pathway Commons Protein-Protein Interactions	1.0	null
NR2F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88045
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3171
SH3PXD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2961
E2F4_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ASS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66802
RIMS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30722
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
TC-71	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PDCD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00549
GSE226316_4_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.77486
PBXIP1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC13137955-ijbsv22p4243s2.xlsx-Sheet1-hTFtarget_E2F3_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
TOMM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61215
BC-63-DM76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223397
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
CA-63-LW25_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.28594
U343	Achilles Cell Line Gene Essentiality Profiles	1.0	1.27867
PGK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77099
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOS_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AVPI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83691
GSE185944_2_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CF-87-AS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.311435
BRAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25229
ILK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7787
GSE142684_4_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PEX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60337
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3F3A	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE89767_7_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-gene_id_y_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
RAB38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8608
GTEX-XQ3S-1426-SM-4BOPR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893215
Formate dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.814
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RXRA	ENCODE Transcription Factor Targets	1.0	null
most	GeneRIF Biological Term Annotations	1.0	null
H3K36me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Water	HMDB Metabolites of Enzymes	1.0	null
Elementary body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.902
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.30062
BHLHE40_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A119-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210885_3_v_7_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE57871_8_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-PWCY-1726-SM-48TD3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17312
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFG8-1626-SM-4LVMB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00117
GSE213588_8_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CHLORPROGUANIL	DGIdb Drug Targets 2026	1.0	6.6165
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07366
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.7227
dg2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.551
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCA-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00853
NPLOC4	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E1-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35742
MBD4	ENCODE Transcription Factor Targets	1.0	null
CXCR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75403
TBP_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ovary	HPA Tissue Gene Expression Profiles	-1.0	-1.05138
SW1783	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.72328
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.20461
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04033
HSD17B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56283
RNF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81902
HEXIM2	Pathway Commons Protein-Protein Interactions	1.0	null
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.68167
CRCGN017_MCF10A.WT.HP_24H:K03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03183
HMGN3	ENCODE Transcription Factor Targets	1.0	null
DACT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94563
CRCGN008_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3023
POLR2AphosphoS5_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Organellar ribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.811
primary auditory cortex (core)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.95522
H3K27ac_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.36087
POLR2AphosphoS5_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEL270	DepMap CRISPR Gene Dependency	1.0	2.73914
organelle	GO Cellular Component Annotations 2015	1.0	null
SLC39A14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64556
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06545
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S11-Table_S11_MR_resluts_of_brain_pQTL_and_any_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ3S-1126-SM-4BOPK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21804
Meningococcal meningitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
FB-39-CW59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.967144
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MCM3	Pathway Commons Protein-Protein Interactions	1.0	null
RecFOR complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.629
GTEX-TMMY-0008-SM-4DXU3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918244
GSE186223,GSE186224_6_v_3_hmces_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79444
HSPA8	Pathway Commons Protein-Protein Interactions	1.0	null
ATP6V0E2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10357
TBL2	Pathway Commons Protein-Protein Interactions	1.0	null
IFT27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98595
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40956
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IA-27-CK10_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.288717
CERS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49463
SETDB1	ENCODE Transcription Factor Targets	1.0	null
SLIRP	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN013_HEPG2_24H:N07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06373
SCN1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16571
GSE199874_4_v_5_gabpb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26355
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLRMT	Pathway Commons Protein-Protein Interactions	1.0	null
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
smooth muscle	HPA Tissue Protein Expression Profiles	-1.0	-1.78868
CRCGN015_MCF10A_48H:I07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.08353
H3K36me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SEC14L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27421
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45255
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN008_HEPG2_24H:C16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00945
SOX2-20726797-SW620-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ZR7530	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37054
LNCAP	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00468
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EM-01A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DF-00-BU08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.3269
hippocampus (hippocampal formation)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.26309
ZBED3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26123
PHF5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60161
HPBALL	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74701
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HMGB3	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN012_HEPG2_24H:G19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.16334
GTEX-SSA3-0008-SM-47JWJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13077
GTEX-P44H-2426-SM-2XCEJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25786
POLR2A_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HLTF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40956
HNRNPL	Pathway Commons Protein-Protein Interactions	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KW-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATP6V1G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.924
GTEX-S32W-1426-SM-4AD66	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939144
Acute Myeloid Leukemia_LAML_TCGA-AB-2920-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE137144_4_v_6_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PDCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30067
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ESYT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59523
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00593
KMS20	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4071
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5707-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.886025
peptide deformylase activity	GO Molecular Function Annotations 2025	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
OAW42	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.20631
CRCGN015_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.75645
GTF2B	ENCODE Transcription Factor Targets	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A5KC-11A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZSWIM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32433
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30516
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.23796
USF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WHSC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCFL	ENCODE Transcription Factor Targets	1.0	null
FOXP2	ENCODE Transcription Factor Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J6-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETHE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27391
N-terminal protein acetyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.16
GTEX-R3RS-0008-SM-48FF1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957946
NOB1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN016_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.71815
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149903_0_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JM1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-5.61765
KDM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16169
Prostatic Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8305-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE209938_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.10182
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC12178937-mmc6.xlsx-L_AKAP12_KDvsD_AKAP12_KD_deg_al-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XXEK-0826-SM-4BRWG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967221
FA-45-PN48_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.276077
CRCGN013_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.04387
SH3GLB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69872
PTTG1IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.952
NR2F2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
kidney_b	HPA Tissue Sample Gene Expression Profiles	1.0	1.20849
Kidney Chromophobe_KICH_TCGA-KL-8336-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCC5	DepMap CRISPR Gene Dependency	1.0	2.61564
SLU7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.28438
AC-30-XU83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.300071
CRCGN013_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.24302
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_HEPG2_48H:M08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.12049
NMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70284
GTEX-WH7G-0002-SM-4LVN9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09052
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.79851
POLR2A_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
INTS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92783
SIHA	CCLE Cell Line Gene CNV Profiles	1.0	2.82787
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35015
PHLDA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23461
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZIC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.8605
hsa-miR-766	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
TTC30B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89743