association	dataset	threshold value	standardized value
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H64	GDSC Cell Line Gene Expression Profiles	-1.0	-2.14047
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.50343
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.547297
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Addison Disease	DisGeNET Gene-Disease Associations	1.0	null
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
VMRCLCD	DepMap CRISPR Gene Dependency	1.0	2.21172
BATF	ENCODE Transcription Factor Targets	1.0	null
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4149371-pone.0105180.s010.xls-SOX2-GENE_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
testis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.01862
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K57938735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04741
Ralfinamide	DeepCoverMOA Drug Mechanisms of Action	1.0	0.3
nucleus-vacuole junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.787
abnormal podocyte foot process morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Pyramus (VIII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.98783
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05008
GSE158834_2_v_9_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
Entorhinal area, medial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00785
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.86569
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
mantle zone of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60225
TEAD4_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE214335_1_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.947335
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5099-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Meiotic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.049
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47719
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03298
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
abnormal cns myelination	HPO Gene-Disease Associations	1.0	null
regulation of autophagy	GO Biological Process Annotations 2015	1.0	null
EJM	CCLE Cell Line Gene CNV Profiles	1.0	1.58331
hsa-miR-3650	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE65617_2_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
superficial stratum of AHy	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28641
hsa-miR-4713-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
H3K4me3_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7693-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40542
REC1	CCLE Cell Line Gene CNV Profiles	1.0	1.97675
BICR56	CCLE Cell Line Gene CNV Profiles	-1.0	-2.69068
BRD-K65602491	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41843
CCDC152	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07169
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.981982
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE158834_7_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Paramedian lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93304
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04985
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.28864
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24266
CEBPB	ENCODE Transcription Factor Targets	1.0	null
regulation of mitochondrion degradation	GO Biological Process Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-75-6207-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WT1-25993318-PODOCYTE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K76922696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.5942
GSE122215,GSE122217_0_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FAO cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.925
Lung squamous cell carcinoma_LUSC_TCGA-39-5031-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7840052__F7	PFOCR Pathway Figure Associations 2024	1.0	null
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal glomerular capsule visceral layer morphology	MPO Gene-Phenotype Associations	1.0	null
SW620	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-424	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.014
Cytosolic region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.81
other source	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.092375
ZR-82 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.344
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.838972
GSE206400_3_v_4_nusinersen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
SETDB1	ENCODE Transcription Factor Targets	1.0	null
Oculodentodigital dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.135
BRD-K63330804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40593
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.547297
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40385
Ptosis	DisGeNET Gene-Disease Associations	1.0	null
FOXA1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8262
monocarboxylic acid catabolic process	GO Biological Process Annotations 2015	1.0	null
TEAD1	JASPAR Predicted Transcription Factor Targets	1.0	null
digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE169155_5_v_7_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43185
GTEX-PLZ4-1626-SM-3P618	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18885
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.20234
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876523
BRD-K14375485	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09191
POU2F2_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15499
ETS2_KD_GSE62168_259_mouse_mouse trophoblast stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K10317744	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31036
HCC1599	CCLE Cell Line Gene Expression Profiles	1.0	2.48188
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.867937
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.928144
lateral septal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.967924
BRD-K18763924	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1426
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24275
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.744066
BRD-K74506898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0617
TCF7L2_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
multi-organism behavior	GO Biological Process Annotations 2015	1.0	null
Peroxisome biogenesis disorder 11A	ClinVar Gene-Phenotype Associations	1.0	null
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE231648_1_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1337
TCF12	ENCODE Transcription Factor Targets	1.0	null
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48846
peroxisome	GO Cellular Component Annotations 2023	1.0	null
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.6848
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11A-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KDM6A-18722178-U937_AND_SAOS2-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
complete neonatal lethality	MPO Gene-Phenotype Associations	1.0	null
BRD-K09975619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37997
ribostamycin-2705	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
molecular layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65977
496100368_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.33517
amygdaloid complex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.50815
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.40308
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
COLO-684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC7401461-iovs-61-3-10_s001.xlsx-Sheet1-SRY_SRY	Rummagene Transcription Factor Associations 2026	1.0	null
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
CRCGN015_MCF10A.TP53.M_24H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.02442
mitochondria-associated endoplasmic reticulum membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.076
NCI H322M	BioGPS Cell Line Gene Expression Profiles	1.0	2.09974
REST_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the cerebral cortex	HPO Gene-Disease Associations	1.0	null
BRD-K41334119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05797
SU-DHL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07667
GSE244710_1_v_2_srsf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BATF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE57871_6_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
ENKD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08205
CTCF_GM12872_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fastigial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12633
Muscle Spasticity	DisGeNET Gene-Phenotype Associations	1.0	null
USF1_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K96239538	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10176
ZZZ3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WEY5-0008-SM-4LMKC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909347
GTEX-R55E-0006-SM-2TC5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.989803
ZNF263	ENCODE Transcription Factor Targets	1.0	null
Basolateral amygdalar nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.0672
GSE88819_7_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Mesothelioma_MESO_TCGA-LK-A4O4-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Depressed Nasal Bridge	DisGeNET Gene-Phenotype Associations	1.0	null
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QV44-0826-SM-2S1RG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23234
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
loperamide-1949	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Decreased Liver Function	DisGeNET Gene-Phenotype Associations	1.0	null
H3K23ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
mantle zone of AHy	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28568
6870_PSMD2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.560114
GTEX-QVJO-0126-SM-3GIK4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61252
BRD-K70923850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19893
BRD-K88200581	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00034
Brushfield Spots	DisGeNET Gene-Phenotype Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CG-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF282	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.496
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4619-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ovary cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.447192
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EJ-11A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6362-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Neurotoxicity Syndromes	CTD Gene-Disease Associations	1.0	1.45936
BRD-K41790019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21934
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064753
hepg2	HPA Cell Line Gene Expression Profiles	1.0	1.1374
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.12724
Mpp10 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.712
BRD-K86159732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37939
intermediate stratum of AStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50853
GTEx Heart 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	-1.0	-9.168
internal granular layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.73284
ABC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.20984
CRCGN017_MCF10A.TP53.M_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.34361
SPI1-22790984-ERYTHROLEUKEMIA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
JD-44-KF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.221849
TAF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.881903
UBTF_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00074
BRD-K03810133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80869
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837857
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05665
hsa-miR-664	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
peroxisomal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.78255
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RUSQ-0226-SM-47JWT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17715
H3K27ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ABC-1	GDSC Cell Line Gene Expression Profiles	1.0	1.58256
TCP1	Pathway Commons Protein-Protein Interactions	1.0	null
BL172 (MDM2)	NURSA Protein Complexes	1.0	null
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.870169
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89968
Microbody lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.569
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70533
amygdalohippocampal transition zone, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.825976
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A6QY-01A-12R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
2796_EXOSC9_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.62404
ETS1-20019798-JURKAT-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4238
Abnormal Chorioretinal Morphology	DisGeNET Gene-Disease Associations	1.0	null
CAL-51	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-1.9795
bradykinesia	MPO Gene-Phenotype Associations	1.0	null
496100345_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.11754
YY1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K19046167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53973
GTEX-S7SE-0011-R1A-SM-2XCDE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03721
Cortical amygdalar area, posterior part, lateral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.593
thyroid gland	HPA Tissue Gene Expression Profiles	1.0	0.894156
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.39082
H3K4me1_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-58-8387-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sensorineural hearing impairment	HPO Gene-Disease Associations	1.0	null
CRCGN017_MCF10A.WT.HP_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.55415
CREB1-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
limb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.096231
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
abnormality of the anterior segment of the eye	HPO Gene-Disease Associations	1.0	null
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
neuron degeneration	MPO Gene-Phenotype Associations	1.0	null
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40427
Fatty acid beta-oxidation multienzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.622
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.99435
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.21875
MYBL2	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6362-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
brain stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.096506
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.828933
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Curcumin_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0131343
CEBPD	ENCODE Transcription Factor Targets	1.0	null
GTEX-T6MN-0008-SM-4DM7H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980553
amygdaloid complex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.977073
H3K27ac_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
abnormal glucose homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.199555
RFX5	ENCODE Transcription Factor Targets	1.0	null
thymus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.66174
BRD-K83684822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03353
BRD-K49472569	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16609
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4519	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
MM1S	CCLE Cell Line Gene Expression Profiles	-1.0	-1.70757
KCL22	DepMap CRISPR Gene Dependency	1.0	3.15374
TEAD4	ENCODE Transcription Factor Targets	1.0	null
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.253
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054016
GTEX-QEL4-1426-SM-447AC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890562
Integral component of peroxisomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.954
abnormality of the optic nerve	HPO Gene-Disease Associations	1.0	null
SH3 domain	InterPro Predicted Protein Domain Annotations	1.0	null
BRD-K17904341	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07633
NCIN87	DepMap CRISPR Gene Dependency	1.0	2.73738
decreased liver function	HPO Gene-Disease Associations	1.0	null
BRD-K87167435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.33825
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
signal	GeneRIF Biological Term Annotations	1.0	null
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K56ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-RTLS-0008-SM-48FET	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39212
GSE125007,GSE125008_10_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
pex13p	GeneRIF Biological Term Annotations	1.0	null
GSE234340_1_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.86274
BRD-K43126701	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29294
targeting	GeneRIF Biological Term Annotations	1.0	null
CRCGN015_HEPG2_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.92476
PMC3594231-pone.0057799.s001.docx-9-ENSG00000131408_NR1H2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K50498614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.13244
FOXA2	ENCODE Transcription Factor Targets	1.0	null
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_12_v_9_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
MYB_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WWYW-0826-SM-3NB2X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84878
GTEX-OXRP-0326-SM-33HBJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00366
GSE203158_1_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GATA1	ENCODE Transcription Factor Targets	1.0	null
BRD-K64602559	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23981
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1628
abnormal body size	MPO Gene-Phenotype Associations	1.0	null
AD-83-MW95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.329976
BRD-K29525414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21905
ventral tegmental area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39576
TAL1	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-92-8064-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bloodstream form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.606
TCP11L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19774
CNOT1	Pathway Commons Protein-Protein Interactions	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K57443386	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.13553
TOV-21G	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K47724892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01858
OVMANA	CCLE Cell Line Gene CNV Profiles	1.0	1.40898
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.836209
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K30823221	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10912
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SIX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05218
dorsolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1674
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.35532
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.295
PAX5_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5950532__F6	PFOCR Pathway Figure Associations 2024	1.0	null
Peroxisome biogenesis disorder 11A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.403
Linear skin defects with multiple congenital anomalies 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.226
abnormality of the lens	HPO Gene-Disease Associations	1.0	null
KDM5B	ENCODE Transcription Factor Targets	1.0	null
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
CRCGN017_MCF10A.WT.HP_24H:G17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.46895
Cuticle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.08
BRD-K04196669	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58593
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular protein transmembrane transport	GO Biological Process Annotations 2023	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5J1-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Folium-tuber vermis (VII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.04794
abnormality of cardiac ventricle	HPO Gene-Disease Associations	1.0	null
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.981539
Chromosome 2p16.1-p15 deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.443
PML_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5178-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K37356599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.47808
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5UN-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K61182411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2168
Nem1-Spo7 phosphatase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.652
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.867937
BHLHE40_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.44054
SMAD3-18955504-HACAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC6080909-JEM_20171312_TableS1.xlsx-Each_THP1_Pulldown_Expt_Targets-Unnamed_9_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
HT	CCLE Cell Line Gene CNV Profiles	-1.0	-2.75817
HCFC1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOPS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.773
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1848
CRCGN015_MCF10A.TP53.M_24H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0048
FD-29-MM50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222637
GSE217115_2_v_0_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN010_HEPG2_24H:B23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.92574
GSE126621,GSE126920_1_v_0_dppa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216538_1_v_3_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K19699893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70047
Protozoan form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.428
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.929154
UK 383367	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.58
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30232
PMC11554977-40199_2024_523_MOESM2_ESM.xlsx-Sheet1-Supplement_2_Metformin_Drug_Sensitivity_and_Damaging_Mutation_by_using_PRISM_Repurposing_Primary_Screen_and_Damaging_Mutation_in_DepMap_PRDM6	Rummagene Transcription Factor Associations 2026	1.0	null
chlorpropamide-141	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.164
MAX	ENCODE Transcription Factor Targets	1.0	null
respiratory insufficiency	HPO Gene-Disease Associations	1.0	null
hsa-miR-26a	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
GSE134375_3_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.933581
PMC10319804-41467_2023_38747_MOESM10_ESM.xlsx-cARID1A_KD_genes_down-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SRF_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPK5-0008-SM-4IHJD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934592
C170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
BRD-K11979048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66112
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00008
SMAD3	ChEA Transcription Factor Targets	1.0	null
SIN3A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-16	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.704
hsa-miR-548x	TargetScan Predicted Conserved microRNA Targets	1.0	0.017945
PNMA8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06913
LBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8971
CTV1DM	DepMap CRISPR Gene Dependency	1.0	2.47246
SP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4465	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
TCF3	ChEA Transcription Factor Targets	1.0	null
Liver Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.57281
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostatic Neoplasms	CTD Gene-Disease Associations	1.0	1.12838
NCIH2052	CCLE Cell Line Gene CNV Profiles	1.0	1.83796
ES6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
terminal subparaventricular area of THyA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17128
SPI1	ENCODE Transcription Factor Targets	1.0	null
BRD-K22510845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94967
MLMA	COSMIC Cell Line Gene CNV Profiles	1.0	3.12177
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of corneal stroma	HPO Gene-Disease Associations	1.0	null
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.08969
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.47439
Neoplasms	CTD Gene-Disease Associations	1.0	1.51683
D-bifunctional protein deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.226
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table3_WBBC_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K30252238	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01046
GTEX-RVPU-0011-R10A-SM-2XCAH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39693
Polymeric IgA immunoglobulin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.703
Large Face	DisGeNET Gene-Phenotype Associations	1.0	null
MCF7	BioGPS Cell Line Gene Expression Profiles	1.0	1.40139
BRD-K88960810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40851
NCI-H2342	GDSC Cell Line Gene Expression Profiles	1.0	2.28995
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the outer ear	HPO Gene-Disease Associations	1.0	null
Extrinsic component of intraperoxisomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.802
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table2_ChinaMAP_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE185944_0_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE81803,GSE81912_4_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3471-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4753-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GSE158834_1_v_9_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_BMS-911543_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0120958
GSE158834_10_v_8_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WFG8-1926-SM-4LVM1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09765
decreased total tissue mass	MPO Gene-Phenotype Associations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RM-01A-21R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
hsa-miR-217	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
urinarybladder_5c	HPA Tissue Sample Gene Expression Profiles	1.0	0.893972
POU2F2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1792	COSMIC Cell Line Gene CNV Profiles	1.0	3.12177
NFATC1	ENCODE Transcription Factor Targets	1.0	null
medial amygdala, anterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34689
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02777
abnormal peroxisome morphology	MGI Mouse Phenotype Associations 2023	1.0	null
organelle	LOCATE Curated Protein Localization Annotations	1.0	null
BRD-K87092114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43624
cerebellum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16182
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.868925
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.825596
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19763
FOXA2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_GSK J1_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0153518
VZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34616
USF1_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebral cortex cell migration	GO Biological Process Annotations 2015	1.0	null
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.961785
8229_SNRPD2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.597735
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.26852
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.869058
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.36779
PMC6638267__F8	PFOCR Pathway Figure Associations 2023	1.0	null
20368555-TS-2	GeneSigDB Published Gene Signatures	1.0	null
BL1834 (CAMK4)	NURSA Protein Complexes	1.0	null
SOX9-26525672-CHIP-SEQ-LIMBBUDS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6954-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
abnormality of prenatal development or birth	HPO Gene-Disease Associations	1.0	null
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCV JFH-1_12Hour_20200238_GSE20948	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.36113
BRD-K18298066	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10134
Short Stature	DisGeNET Gene-Phenotype Associations	1.0	null
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
telencephalon cell migration	GO Biological Process Annotations 2015	1.0	null
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:E11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.18569
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33706
abnormality of limb bone	HPO Gene-Disease Associations	1.0	null
Autosomal genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
TMP269	DeepCoverMOA Drug Mechanisms of Action	1.0	0.25
GATA3_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.863887
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.216
abnormality of limb bone morphology	HPO Gene-Disease Associations	1.0	null
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19395
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K11143221	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34999
GTEX-RVPU-0011-R3A-SM-2XCAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44781
DB-01-BR68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.221466
lethality during fetal growth through weaning	MPO Gene-Phenotype Associations	1.0	null
IQGAP2	Pathway Commons Protein-Protein Interactions	1.0	null
Corneal Opacity	DisGeNET Gene-Phenotype Associations	1.0	null
peroxisome	LOCATE Curated Protein Localization Annotations	1.0	null
GTEX-SIU8-0008-SM-4BRUC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41481
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QMRM-0008-SM-447B1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06896
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.877143
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TUBB	Pathway Commons Protein-Protein Interactions	1.0	null
Crystalloid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.555
organic substance catabolic process	GO Biological Process Annotations 2015	1.0	null
Macrocephaly	DisGeNET Gene-Disease Associations	1.0	null
GSE156115_2_v_1_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE66014_0_v_1_perhexiline_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:B23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01835
FOXA1-21915096-LNCAP-1F5-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
pallidohypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.91146
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30196
GTEX-WYBS-0626-SM-3NMAS	GTEx Tissue Sample Gene Expression Profiles	1.0	2.88193
GTEX-XOTO-0011-R1B-SM-4B65C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.862047
Allpo	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.656
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SSP25	DepMap CRISPR Gene Dependency	1.0	2.59334
AD-51-FB60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.303343
BRD-K29547381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37297
abnormal voluntary movement	MPO Gene-Phenotype Associations	1.0	null
GSE158834_2_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE198165,GSE198166_6_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GABPA_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hyperglycemia	CTD Gene-Disease Associations	1.0	1.20097
K562_Altretamine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0185288
suprachiasmatic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2886
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6366-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-5963-02A-12R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
muscle weakness	HPO Gene-Disease Associations	1.0	null
biogenesis	GeneRIF Biological Term Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A5DX-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TKKK	DepMap CRISPR Gene Dependency	1.0	2.63071
Dense body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.619
hsa-miR-193b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
496100510_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.57246
BRD-K88936403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06955
BRD-K57388326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02492
Peroxisomal biogenesis disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.378
BRD-K24369860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18427
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cornelia de Lange syndrome 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.159
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Long Narrow Head	DisGeNET Gene-Disease Associations	1.0	null
GTEX-U3ZN-0002-SM-3NMDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00269
BRD-K23997756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92381
BRD-K72646819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68377
PMC5263239-mmc2.xls-SEM_-_MLL-AF4-All_targets_genes_names_2597_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE224096_2_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Tapetum lucidum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.77
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.28439
2367_DPY30_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.927226
NCI-H2342	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20N-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GABPA_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-5630-01A-01R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38819
bounding membrane of organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.1122
Lung squamous cell carcinoma_LUSC_TCGA-85-8070-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar nuclei of CbV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01836
NFIC_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPAR-26484153-CHIP-SEQ-NCI-H1993-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-3613-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.013856
dorsolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.841532
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.0119
GTEX-S7PM-0011-R5A-SM-3NM8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2027
Nucleus of the lateral olfactory tract, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86663
Macitentan_NCI-H1792	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.018229
Primary somatosensory area, lower limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	4.44139
BRD-K97106314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.3252
BACH1	ENCODE Transcription Factor Targets	1.0	null
verapamil-161	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
VI, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.24255
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.642
Simple lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55539
Adrenoleukodystrophy, Neonatal	DisGeNET Gene-Disease Associations	1.0	null
molecular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47775
Brain ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.216
PCI-4B	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.73402
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K07501194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0747
Alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
Paraflocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0405
ZNF384	ENCODE Transcription Factor Targets	1.0	null
aplasia/hypoplasia involving bones of the skull	HPO Gene-Disease Associations	1.0	null
hsa-miR-4282	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
mortality/aging	MPO Gene-Phenotype Associations	1.0	null
GTEX-P44H-0008-SM-48TDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46635
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100594_TCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.74206
ZNF229	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25108
hsa-miR-513b	TargetScan Predicted Conserved microRNA Targets	1.0	0.31417
metencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.105447
PCI6A	DepMap CRISPR Gene Dependency	1.0	3.47019
GSE174701_4_v_7_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-O5YT-2126-SM-3MJGD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91
BRD-K94858557	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.17627
BRD-K30358777	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07087
cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38512
Cortical amygdalar area, posterior part, medial zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2793
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02351
BRD-K91085913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9982
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UKE-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.892907
Small Intestine - Terminal Ileum	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.39141
4932_MED12_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.526704
rosiglitazone_mus musculus_gpl8321_gds4021	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC6357748-aau9223_Table_S1.xlsx-CD4_T_-_LPS-Unnamed_0_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal location of ears	HPO Gene-Disease Associations	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2423
superficial stratum of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68029
abnormality of the lung	HPO Gene-Disease Associations	1.0	null
GSE126621,GSE126920_1_v_3_dppa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TCCSUP	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44674
GSE242555_1_v_0_fn3k_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.925824
GATA3	ENCODE Transcription Factor Targets	1.0	null
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K33967062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57565
abnormality of the head	HPO Gene-Disease Associations	1.0	null
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16629
CDX2-21402776-INTESTINAL-VILLUS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JA-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-197-3p	MiRTarBase microRNA Targets	1.0	null
LNCAP	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.73486
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
interacts	GeneRIF Biological Term Annotations	1.0	null
protein binding	GO Molecular Function Annotations 2015	1.0	null
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
15260889-TableS2a	GeneSigDB Published Gene Signatures	1.0	null
abnormality of the systemic arterial tree	GWASdb SNP-Phenotype Associations	1.0	0.114561
GTEX-T6MN-2526-SM-32PMN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849422
doxorubicin_homo sapiens_gpl570_gse46493	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
IZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.47611
GSE98898_7_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC18A3_KD_GDS4325_618_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Entorhinal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03472
BRD-K37398853	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12877
GTEX-TMMY-1626-SM-4DXTY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824938
BRD-K32170456	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73601
abnormal kidney cortex morphology	MPO Gene-Phenotype Associations	1.0	null
peripheral portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.69549
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cerebellum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.903647
H3K36me3_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K10528627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73964
Chloroplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.374
abnormality of muscle physiology	HPO Gene-Disease Associations	1.0	null
cortex of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68098
GTEX-T6MO-0008-SM-4DM6T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07492
Brain Lower Grade Glioma_LGG_TCGA-DU-8165-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6299095-41389_2018_108_MOESM4_ESM.xlsx-T47D-TRPS1_peak-gene_symbol_TRPS1	Rummagene Transcription Factor Associations 2026	1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
isthmus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37288
PA-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.902
ACHN	BioGPS Cell Line Gene Expression Profiles	1.0	1.00286
CREM-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
6797_PRPF3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.593593
BRD-K31521981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17151
HNF4G	ENCODE Transcription Factor Targets	1.0	null
threonine	GeneRIF Biological Term Annotations	1.0	null
BRD-K20724649	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.1892
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.26623
TCF3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Entorhinal area, medial part, dorsal zone, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04671
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7439
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-HB-A43Z-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A90249268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58582
RAD21_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RARA-24833708-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC8724844-bt-30-1-98-supple2.xlsx-GO_BP-TFAP4_TFAP4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
corneal opacity	HPO Gene-Disease Associations	1.0	null
H3K4me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ectopic calcification	HPO Gene-Disease Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7424-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K96075847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14359
Retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.062
TCP11L1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-PX3G-2626-SM-2I3EG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896212
BRD-K59000771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27226
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.879391
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVCA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00677042
STAT3	ChEA Transcription Factor Targets	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A68F-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Seminiferous epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.781
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6516-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Inferior olivary nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.936
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB1-F2del_18Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.48032
CBX3_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IFT80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06175
Pituitary	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.07824
NCIH226	DepMap CRISPR Gene Dependency	1.0	4.0832
H3K4ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MU-A5YI-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
macrovesicular hepatic steatosis	MGI Mouse Phenotype Associations 2023	1.0	null
PMC7518873-abb0205_Table_S1.xls-TFEB_targets-ensembl_TFEB	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of the stomach	HPO Gene-Disease Associations	1.0	null
thin cerebral cortex	MPO Gene-Phenotype Associations	1.0	null
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11117
GTEX-U3ZN-1226-SM-4DXUD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968449
superior colliculus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.2433
H3K4me1_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4T-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
respiratory distress	MGI Mouse Phenotype Associations 2023	1.0	null
High Forehead	DisGeNET Gene-Phenotype Associations	1.0	null
HCC202	CCLE Cell Line Gene Expression Profiles	1.0	1.43008
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.92254
Abnormality Of Epiphysis Morphology	DisGeNET Gene-Phenotype Associations	1.0	null
single-organism cellular localization	GO Biological Process Annotations 2015	1.0	null
Tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.025
AC-80-DI95_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.219503
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EE-98-PF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.268308
H3K9ac_Rectal Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Sarcosine oxidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.111
ZBTB33	ENCODE Transcription Factor Targets	1.0	null
BRD-K76415727	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05669
abnormality of the genitourinary system	HPO Gene-Disease Associations	1.0	null
solanine-2808	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WFG7-0326-SM-3GILI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20413
GSE222758_0_v_3_clofazimine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Dentate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16844
BRD-K13289658	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0526
abnormality of the lower urinary tract	HPO Gene-Disease Associations	1.0	null
peroxisome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.975309
Estrone sulfate (potassium)_COLO 205	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00789045
Imago	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.557
cranial nerve paralysis	HPO Gene-Disease Associations	1.0	null
J82	CCLE Cell Line Gene Expression Profiles	-1.0	-1.70021
zellweger syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	2.24683
BRD-K27914478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.21864
seminiferous tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.143071
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lobule III	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86518
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
microbody lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.85045
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K32723442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93921
8190_SMU1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.57906
RELA	ENCODE Transcription Factor Targets	1.0	null
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.218864
Oliva	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.621
Celiac disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.931
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-562	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GTEX-WYJK-0005-SM-3NMA1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30307
fatty acid oxidation	GO Biological Process Annotations 2015	1.0	null
Neurobehavioral Manifestations	CTD Gene-Disease Associations	1.0	1.36447
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27023
hsa-miR-597	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
BRD-K86070914	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31138
cellular catabolic process	GO Biological Process Annotations 2015	1.0	null
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.409
heptaminol-7313	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
abnormal brain morphology	MPO Gene-Phenotype Associations	1.0	null
GSE153258_1_v_0_dcp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BDCA4+_DentriticCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.909648
homooligomerization	GeneRIF Biological Term Annotations	1.0	null
GTEX-WVLH-3026-SM-3MJG9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.981621
abnormality of calvarial morphology	HPO Gene-Disease Associations	1.0	null
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Endoplasmic reticulum Sec complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.975
POLR2A_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.29453
LGE-VZ border region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04552
peroxisome	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K59239787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.15407
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A5Y1-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intrinsic component of organelle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE125014_1_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-4652-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
superficial stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11895
Peroxisomal acyl-CoA oxidase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.427
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62784
LAMA84	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6331
GSE139455_2_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K22338979	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29387
BRD-K33956641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4258
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of body height	HPO Gene-Disease Associations	1.0	null
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MT-0011-R8a-SM-2I5GU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01255
Abnormality Of Metabolism/Homeostasis	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68799
BRD-K82292504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13688
GSE60837_0_v_3_bcl9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTBP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZKSCAN1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-N-SH	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.43988
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.25529
15793299-TableC	GeneSigDB Published Gene Signatures	1.0	null
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
EP300_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16679
L1236	CCLE Cell Line Gene CNV Profiles	1.0	1.7911
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.51902
Lung adenocarcinoma_LUAD_TCGA-55-A494-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149264,GSE149267_9_v_1_trp53_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
medial amygdala, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69713
Lung adenocarcinoma_LUAD_TCGA-95-A4VK-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC827	DepMap CRISPR Gene Dependency	1.0	2.67956
hsa-miR-15a	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
GSE190235_1_v_2_foxo3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BLACAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03108
SP1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-3026-SM-4B65M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.844574
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NL3H-0011-R2a-SM-2I3GG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877398
HT-1080	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.09591
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BM-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98399
ED-05-LQ40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.316666
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XV7Q-2426-SM-4BRV8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942893
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.433419
PBX3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40696
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K20091931	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05309
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
macrocephaly	HPO Gene-Disease Associations	1.0	null
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41223
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBJ-2026-SM-3NB1R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898561
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE239373_0_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
duodenum	HPA Tissue Protein Expression Profiles	1.0	1.02714
GATA3_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Meprednisone_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0120525
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11172
dorsolateral part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20544
H3K4me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
X-linked recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.042
diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.278716
A549_Enzastaurin_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.014731
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.05842
layer V of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.5555
substitution	GeneRIF Biological Term Annotations	1.0	null
JARID1A-20064375-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K00418890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85306
BRD-K10055064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02573
GC-04-UF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.228282
developmental regression	HPO Gene-Disease Associations	1.0	null
sertoli cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.253578
H3K9ac_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K74826740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15748
slanting of the palpebral fissure	HPO Gene-Disease Associations	1.0	null
FOXA1_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RUNX1-17652178-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE190384,GSE190386_6_v_8_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE158834_7_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNU324	CCLE Cell Line Gene CNV Profiles	-1.0	-2.29324
OE-84-HO42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223569
hsa-miR-4795-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
ChIP_JARID1A_20064375	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
REST_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of limbs	HPO Gene-Disease Associations	1.0	null
GTEX-U4B1-0826-SM-4DXTW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90662
NCI-H1792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
doxylamine-1973	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE160246_9_v_1_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.372958
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Visual Impairment	DisGeNET Gene-Phenotype Associations	1.0	null
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
FOXA2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K31300534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20373
PMC4149371-pone.0105180.s010.xls-OCT4-GENE_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.97619
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.538893
GSE136742,GSE136744_2_v_3_setd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
U2AF2_02_170	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59475
hsa-miR-3545-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Climbing fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.505
GTEX-SE5C-0008-SM-4B64J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54378
abnormality of the ocular region	HPO Gene-Disease Associations	1.0	null
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.965973
FOSL2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
when	GeneRIF Biological Term Annotations	1.0	null
abnormality of the inner ear	HPO Gene-Disease Associations	1.0	null
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.881903
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.46505
GSE119564_1_v_3_zfp217_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Entorhinal area, medial part, dorsal zone, layer 6	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59425
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45308
GTEX-WFG8-0008-SM-4LVN6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874407
ATF2	ENCODE Transcription Factor Targets	1.0	null
GSE206270_2_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51787
Intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.350001
abnormality of the cardiovascular system	HPO Gene-Disease Associations	1.0	null
retrorsine-2129	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TEAD4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX3_01_27	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.58654
raphe magnus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.37427
pm85	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.211
SIX5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8437-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA1_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.309
Bone inflammation disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.571
cerebellum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00217
CRCGN015_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1515
CRCGN015_MCF10A.WT.HP_24H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9208
BC-26-LE04_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.336986
CRCGN015_MCF10A.TP53.M_24H:F21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5067
H3K27ac_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6090-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-V955-1126-SM-4JBH3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862394
internal granular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44788
Lung squamous cell carcinoma_LUSC_TCGA-60-2726-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7369-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
behavior	GO Biological Process Annotations 2015	1.0	null
17660535-TableS4a	GeneSigDB Published Gene Signatures	1.0	null
H3K27ac_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CF-97-AV07_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208683
Severe Global Developmental Delay	DisGeNET Gene-Phenotype Associations	1.0	null
TBP_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC-20876797-MEDULLOBLASTOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
IRF4_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFK_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A815-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
9505BIK	DepMap CRISPR Gene Dependency	1.0	3.58088
PAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8593
GTEX-X585-0011-R6A-SM-46MVJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.84121
BRD-A61046366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22508
COR-L279	GDSC Cell Line Gene Expression Profiles	-1.0	-1.54812
BRD-K77797840	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84473
abnormal nervous system morphology	MPO Gene-Phenotype Associations	1.0	null
MTA3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Cryptorchidism	DisGeNET Gene-Disease Associations	1.0	null
GATA1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1297	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
alpha-methylacyl-CoA racemase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.704
Zellweger Syndrome	DisGeNET Gene-Disease Associations	1.0	null
hearing abnormality	HPO Gene-Disease Associations	1.0	null
POLR2A_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the zygomatic arch	HPO Gene-Disease Associations	1.0	null
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.8414
Fluconazole	DeepCoverMOA Drug Mechanisms of Action	1.0	0.57
BRD-K22380647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36784
TBP_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LDB1-21186366-BM-HSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K50278697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05588
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.29894
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.998005
BRD-K00789767	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09896
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5134
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43329
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Visual Field Constriction	DisGeNET Gene-Phenotype Associations	1.0	null
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.1587
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.282601
GSE242290_3_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
outer portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.972346
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1	ENCODE Transcription Factor Targets	1.0	null
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9991
ELF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H4K91ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-3.38707
Glycolate oxidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.802
REST_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K68890376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00014
EM2	DepMap CRISPR Gene Dependency	1.0	2.02842
peroxisomal part	GO Cellular Component Annotations 2015	1.0	null
infantile muscular hypotonia	HPO Gene-Disease Associations	1.0	null
CTCF_GM12872_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUN_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ssh1 translocon complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.809
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.89601
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67438
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.042441
Sleeping sickness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.375
Folium-tuber vermis (VII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.05285
nucleus of diagonal band	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.894149
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lobule II, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40371
SPI1_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
protein to membrane docking	GO Biological Process Annotations 2015	1.0	null
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
abnormal renal corpuscle morphology	MPO Gene-Phenotype Associations	1.0	null
Abnormal Vision	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K05616059	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08722
GSE185944_5_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IRF1	ENCODE Transcription Factor Targets	1.0	null
coronary artery disease	GWASdb SNP-Phenotype Associations	1.0	0.490196
A-Netherlands-602-2009(H1N1)_30Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.69086
primary motor cortex (area M1, area 4)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02882
POLR2A_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of cardiovascular system physiology	HPO Gene-Disease Associations	1.0	null
Hyperreflexia	DisGeNET Gene-Phenotype Associations	1.0	null
MBD4	ENCODE Transcription Factor Targets	1.0	null
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060541
p95	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.845
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79075
Peroxin 13, N-terminal	InterPro Predicted Protein Domain Annotations	1.0	null
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEX30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40798
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4074-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-MB-A8JL-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K11696817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.50966
Bounding membrane of organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Neck	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.18
MDA-MB-231	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.829682
Uvula (IX)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40411
abnormal axial skeleton morphology	HPO Gene-Disease Associations	1.0	null
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Gilles De La Tourette Syndrome	DisGeNET Gene-Disease Associations	1.0	null
mitochondrion-derived vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.632
Piriform-amygdalar area, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.93567
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1273f	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
HNF4A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
X-linked monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.969
BRD-K19089958	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63912
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
TCF7L2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K21254338	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67167
FCF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03469
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
USF1_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-1262	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Metabolism of proteins	Reactome Pathways 2024	1.0	null
EP300_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A388	DepMap CRISPR Gene Dependency	1.0	2.19194
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09733
Lung adenocarcinoma_LUAD_TCGA-64-1677-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.01293
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6790-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ventropallial amygdalopiriform area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07143
deep layers of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.931982
JB-75-NC66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.548867
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.26016
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.09279
TBP	ENCODE Transcription Factor Targets	1.0	null
abnormality of coordination	HPO Gene-Disease Associations	1.0	null
RUNX1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
RAD21_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Peroxisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.035
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE151612_0_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K36298208	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0232
GSE189356_5_v_6_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PEX10	Pathway Commons Protein-Protein Interactions	1.0	null
TEAD4_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebral cortex cell migration	GO Biological Process Annotations 2023	1.0	null
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00024
JARID1A-20064375-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
protein localization	GO Biological Process Annotations 2023	1.0	null
brownfat	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.59704
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE184892_6_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KDM5A	ENCODE Transcription Factor Targets	1.0	null
BRD-K90644597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.14176
intrinsic component of organelle membrane	GO Cellular Component Annotations 2015	1.0	null
Sarcoma_SARC_TCGA-N1-A6IA-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1324	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
MYOD1	ENCODE Transcription Factor Targets	1.0	null
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
anteverted nares	HPO Gene-Disease Associations	1.0	null
DDIAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03167
CRCGN008_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1635
A-Vietnam-1203_CIP048_RG3-2004(H5N1)_7Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.60171
Brain Lower Grade Glioma_LGG_TCGA-HT-A618-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827673
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of vision	HPO Gene-Disease Associations	1.0	null
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.909537
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	1.0	2.52544
PU.1-20513432-BCELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BC-61-BE07_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.229991
hypoplastic facial bones	HPO Gene-Disease Associations	1.0	null
CEBPB_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.0244
2789_EXOSC2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.541457
BRD-K18562847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6344
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1864
micrognathia	HPO Gene-Disease Associations	1.0	null
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43313
EVSAT	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51267
GSE57871_11_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
TAF1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.98331
S0-EE-XMWH_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208882
HCC1419	CCLE Cell Line Gene Expression Profiles	1.0	1.52405
SIN3A_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFIC	ENCODE Transcription Factor Targets	1.0	null
WB-48-EF24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.273896
JUND	ENCODE Transcription Factor Targets	1.0	null
SBC-5	GDSC Cell Line Gene Expression Profiles	1.0	1.51111
peroxisomal membrane	GO Cellular Component Annotations 2025	1.0	null
Autoimmune disease of skin and connective tissue	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.164
ZBTB33_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal pattern of respiration	HPO Gene-Disease Associations	1.0	null
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9393
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNMC-0826-SM-4DM66	GTEx Tissue Sample Gene Expression Profiles	1.0	2.71553
peroxisomal membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H2BK120ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hearing Loss	DisGeNET Gene-Disease Associations	1.0	null
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11595
Crus 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55144
MXD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11809
ZNF384_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRF_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K29083370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.22241
Lung squamous cell carcinoma_LUSC_TCGA-22-4613-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM204A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20997
BRD-K64317863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09477
GABPA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-A4QR-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4091
647V	CCLE Cell Line Gene CNV Profiles	1.0	1.59342
GABPA_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
Triangular Face	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K62708569	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05727
hsa-miR-548a-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
BRD-K43918778	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38117
cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.562602
abnormality of the hand	HPO Gene-Disease Associations	1.0	null
Cervical intraepithelial neoplasia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.851
CTCF-31629814-HEPATOCYTES-MOUSE-TYROSINEMIA	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
feeding behavior	GO Biological Process Annotations 2015	1.0	null
GTEX-TSE9-0011-R5A-SM-3DB7J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00577
Zellweger syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.359
GTEX-S341-0008-SM-4AD6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12652
neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064914
BRD-K10716948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38701
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5976-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.881903
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07139
FOXA1_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Intestinal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.012
SIX5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU2F2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the optic disc	HPO Gene-Disease Associations	1.0	null
H3K36me3_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
nystagmus	HPO Gene-Disease Associations	1.0	null
ptosis	HPO Gene-Disease Associations	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LD-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ventral medial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11972
496100576_HIP_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.10915
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K11057086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74592
Sensorineural hearing loss	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.379
Peroxisome biogenesis disorders	CTD Gene-Disease Associations	1.0	2.88009
BRD-K06863921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08033
Icterus	DisGeNET Gene-Phenotype Associations	1.0	null
MYOD1_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XGQ4-0008-SM-4AT3Z	GTEx Tissue Sample Gene Expression Profiles	1.0	2.28528
GSE224877_2_v_1_pctp_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE240809_0_v_1_hnrnpa2b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Developmental Regression	DisGeNET Gene-Disease Associations	1.0	null
JIMT1	DepMap CRISPR Gene Dependency	1.0	3.71056
NR2F2	ENCODE Transcription Factor Targets	1.0	null
GI-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE108326_1_v_0_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RARB-27405468-CHIP-SEQ-BRAIN-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HDAC2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K46820725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12448
Abnormality Of The Liver	DisGeNET Gene-Phenotype Associations	1.0	null
HCC827_LUNG	CCLE Cell Line Proteomics	1.0	5.33251
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19244
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052327
GTEX-S7SF-0008-SM-3NM8T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53144
neurodevelopmental abnormality	HPO Gene-Disease Associations	1.0	null
hsa-miR-4771	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
plastid-encoded plastid RNA polymerase complex A	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.548
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.939488
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.899815
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.911921
BRD-K12607407	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41723
paclitaxel_homo sapiens_gpl570_gse39042	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Bed nucleus of the accessory olfactory tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.4042
GSE129389_0_v_5_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-Q2AH-0826-SM-48TZN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929879
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10W-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PEROXISOME BIOGENESIS DISORDER 2B	CTD Gene-Disease Associations	1.0	2.88009
erythroid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.181488
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_317_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
Cataract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
GSE158834_2_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
6652_PPP1R10_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.540908
BRD-K92356505	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5414
functional respiratory abnormality	HPO Gene-Disease Associations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-75-5146-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pentadecanoyl EA	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.29
GSE160373_6_v_4_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Rectum adenocarcinoma_READ_TCGA-F5-6465-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the forehead	HPO Gene-Disease Associations	1.0	null
superior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04907
GABPA_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H1-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72244
SNU503	CCLE Cell Line Gene CNV Profiles	1.0	2.20706
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.83674
LUZP1-20508642-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-S4Q7-0008-SM-3NM8A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21692
T98G	GDSC Cell Line Gene Expression Profiles	-1.0	-1.85175
GTEX-QV31-0008-SM-447AT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34526
ZBTB33_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5883
SIN3A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS 766T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.955597
GSE122215,GSE122217_0_v_4_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intermediate stratum of isBI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10804
hsa-miR-4521	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
abnormality of the palate	HPO Gene-Disease Associations	1.0	null
GTEX-N7MT-0011-R2a-SM-2I3GI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.941763
H3K9ac_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K42960858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83383
H3K27ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K09071517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32211
bone marrow	HPA Tissue Protein Expression Profiles	-1.0	-1.49554
central medullary reticular group, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.915569
organelle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Woronin body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.466
I-II	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.43378
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4076-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU5F1	ChEA Transcription Factor Targets	1.0	null
Granulosa cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.59
Eye degenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.081
BRD-K03923461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.30822
REST_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fatty acid alpha-oxidation	GO Biological Process Annotations 2025	1.0	null
ETS1-22383799-G1ME-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Inner ear disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.337
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.56181
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of muscle size	HPO Gene-Disease Associations	1.0	null
PRDM1	ENCODE Transcription Factor Targets	1.0	null
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.09772
Progressive Muscle Weakness	DisGeNET Gene-Phenotype Associations	1.0	null
primary auditory cortex (core)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09954
496100591_TCx_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.53404
MRTO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57102
Medial amygdalar nucleus, anterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57195
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE174701_4_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
amiprilose-3000	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
496100618_PCx_probable Alzheimer's disease_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.40046
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30196
growth abnormality	HPO Gene-Disease Associations	1.0	null
Ekl	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.587
KLM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09761
BRD-K21759602	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41197
BRD-K06174863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58696
BRD-K96764878	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01488
GSE198165,GSE198166_5_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TY-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4983-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PSDG-0226-SM-33HC1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914113
abnormality of the uvea	HPO Gene-Disease Associations	1.0	null
SARS-BatSRBD_12Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.38346
Skin Neoplasms	CTD Gene-Disease Associations	1.0	1.22306
Septin cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.574
regulation of cellular catabolic process	GO Biological Process Annotations 2015	1.0	null
basomedial amygdaloid nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17293
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22867
KF-18-RY71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.206142
peroxisomal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	2.0943
EPOP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6889
night blindness	HPO Gene-Disease Associations	1.0	null
interrupted	GeneRIF Biological Term Annotations	1.0	null
BRD-K34929471	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11767
GSE196699_0_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB33_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
microtubule-based peroxisome localization	GO Biological Process Annotations 2015	1.0	null
IGR-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.44228
SOX2-16153702-HESC-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.929929
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
PMC5263239-mmc2.xls-SEM_-_MLL-AF4-Non-spreading_targets_gene_names_2497_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XUZC-0126-SM-4BOO6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25965
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.37648
GSE161170,GSE161268_1_v_3_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Colitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.012
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cortical amygdalar area, posterior part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64755
oxidative stress	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-XMD1-0011-R1A-SM-4AT4C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.953786
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
appendix	HPA Tissue Protein Expression Profiles	-1.0	-0.921465
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058127
Brain Lower Grade Glioma_LGG_TCGA-IK-7675-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PADI4	ChEA Transcription Factor Targets	1.0	null
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the eye	HPO Gene-Disease Associations	1.0	null
BRD-K49338297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67714
SIN3A_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE89767_2_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RU72-0011-R6A-SM-2TF71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.980307
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAOV4	DepMap CRISPR Gene Dependency	1.0	4.43969
Infantile Refsum disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.855
GTEX-X4XX-0011-R4B-SM-46MWL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10426
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BE-07-XF09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.219774
NCIH69	CCLE Cell Line Gene CNV Profiles	-1.0	-1.84056
BRD-K71007902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37395
GTEX-WYVS-1726-SM-3NMAY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943129
HNF1A-27111144-CD8+TCELLS-MOUSE-BLOOD-LYMPHOMA	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K39597125	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55878
GTEX-U3ZM-1626-SM-4DXSK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15208
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.31
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
abnormal podocyte foot process morphology	MPO Gene-Phenotype Associations	1.0	null
GTEX-OIZG-0005-SM-2HMJC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18315
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.18228
FLYWCH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04516
nitrofurantoin-2341	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XMK1-0626-SM-4B65A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936912
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.096843
EP300_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL-41	GDSC Cell Line Gene Expression Profiles	-1.0	-1.45081
CEBPB_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebralcortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.966915
TFDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76999
mantle zone of VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07143
BRD-K61555339	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99119
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01373
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.8461
GSE75976_3_v_6_abl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cinchocaine-1969	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
496100347_PCx_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.22638
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.841196
ATF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LRPPRC	Pathway Commons Protein-Protein Interactions	1.0	null
SETDB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.53082
membrane docking	GO Biological Process Annotations 2015	1.0	null
GTEX-NL4W-0011-R9a-SM-2I3G1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20156
Germ tube	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.032
H3K9ac_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-495	TargetScan Predicted Conserved microRNA Targets	1.0	0.175726
microbody membrane	GO Cellular Component Annotations 2025	1.0	null
BCLAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAU1_DELETION_GDS3370_56_human_HeLa	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Strabismus	DisGeNET Gene-Disease Associations	1.0	null
732_B4GALNT1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.667474
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.099
MCAS	DepMap CRISPR Gene Dependency	1.0	2.8246
catabolic process	GO Biological Process Annotations 2015	1.0	null
layer 3 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06213
PMC9385264-NIHMS1828071-supplement-8.xlsx-ESR1-gene_symbol_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QVUS-0011-R9A-SM-3GIJA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02015
regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-GATA3_only-Gene_Name_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal respiratory system morphology	HPO Gene-Disease Associations	1.0	null
GSE167886_3_v_1_chd7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posteriorly rotated ears	HPO Gene-Disease Associations	1.0	null
Monogenic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
PMC6683136-41598_2019_47363_MOESM4_ESM.xlsx-GENE_SET-Positive_correlation_of_ZEB1_and_other_genes_ZEB1	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HW-7490-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CP 94253	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.4
BRD-K64553072	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08978
BRD-K31778201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66732
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
neuron migration	GO Biological Process Annotations 2025	1.0	null
ATF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55D-1426-SM-48FEN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.824931
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.359
r8 part of nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00276
PANC1	DepMap CRISPR Gene Dependency	1.0	2.38349
preweaning lethality	MPO Gene-Phenotype Associations	1.0	null
H4K5ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-SNU-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.98835
GSE175787_4_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE81803,GSE81912_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.987967
GATA3-24758297-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TIM23 mitochondrial import inner membrane translocase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.044
GSE219103,GSE219104_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K07839394	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89273
SOX2	ChEA Transcription Factor Targets	1.0	null
CEBPB_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SSA3-0008-SM-47JWJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90954
ETS1	ChEA Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TG-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
basomedial amygdaloid nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28568
OC-10-FB51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.266184
Medial amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52986
ELK1	ENCODE Transcription Factor Targets	1.0	null
SMC3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HMGN3	ENCODE Transcription Factor Targets	1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
BRD-K45057266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78991
ChIP_TCF3_18347094	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
ventrolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1806
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06181
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fibrosis	CTD Gene-Disease Associations	1.0	1.60454
TMEM170A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07792
Lung squamous cell carcinoma_LUSC_TCGA-22-5492-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K42879623	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58695
Lobules IV-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77251
ventral lateral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06431
PMC12549544-mmc2.xlsx-AA_D1_VS_D7-Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5525
GTEX-Q734-2026-SM-3GADA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05928
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.996288
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.870241
USF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
OVISE	DepMap CRISPR Gene Dependency	1.0	4.36002
GTEX-T6MN-0002-SM-3NMAH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844327
YPEL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00354
H3K27ac_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Impaired Cognition	DisGeNET Gene-Disease Associations	1.0	null
integral component of organelle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
STAT3	ENCODE Transcription Factor Targets	1.0	null
TUBB6	Pathway Commons Protein-Protein Interactions	1.0	null
Bilateral Single Transverse Palmar Creases	DisGeNET Gene-Phenotype Associations	1.0	null
SAOS2	BioGPS Cell Line Gene Expression Profiles	1.0	1.1212
peroxisomal membrane	GO Cellular Component Annotations 2023	1.0	null
GTEX-UPIC-0002-SM-3NMDC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866785
hsa-miR-539	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
TUBB2A	Pathway Commons Protein-Protein Interactions	1.0	null
neurodegeneration	MPO Gene-Phenotype Associations	1.0	null
GSE184892_6_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OXRK-0126-SM-3NB1E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82529
TAF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-SNOS-0008-SM-4DM6I	GTEx Tissue Sample Gene Expression Profiles	1.0	2.22978
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.308612
K562_Busulfan_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0151008
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCLAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4975902-12864_2016_2842_MOESM12_ESM.xlsx-targets_of_IRF8_in_NSCLC-COX7C_IRF8	Rummagene Transcription Factor Associations 2026	1.0	null
Plagl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.8212
GSE146074_9_v_11_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KOSC-2	GDSC Cell Line Gene Expression Profiles	1.0	2.10256
PB-18-HD85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.234204
H3K27ac_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Basomedial amygdalar nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15362
visual loss	HPO Gene-Disease Associations	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.824228
primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.32155
GSE158834_11_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Duodenum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.016
abnormal behavior	MPO Gene-Phenotype Associations	1.0	null
KIT_activemutant_55_GSE17743	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.18954
RT4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.31508
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SP1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
epicanthus	HPO Gene-Disease Associations	1.0	null
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57924
zona incerta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.96938
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10626
vascular disease	GWASdb SNP-Disease Associations	1.0	0.069458
SMAD3-22036565-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K02118124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48939
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Crohn's disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.830103
DYNC2H1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K72933250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04204
H3K4me3_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
G-402	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24565
GSE245270_1_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
mepyramine-5869	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE121198,GSE129782_1_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S33H-1826-SM-4AD65	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836117
GSE239436,GSE239441_0_v_1_keap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RVX-208	DeepCoverMOA Drug Mechanisms of Action	1.0	0.38
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3842
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78471
gliquidone-7301	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K12281552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.54853
COV362	CCLE Cell Line Gene Expression Profiles	1.0	1.39159
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE234340_9_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HNF4A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE123861_1_v_0_sin3a_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K25710391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65896
hsa-miR-3686	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
SMAD4-19686287-HaCaT-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BD-49-MD69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.316376
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.621612
PTRH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.093
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7429-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer 2 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48383
JUND-26020271-SMOOTH-MUSCLE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HNF4G_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFIA_Deficiency_GDS2775_640_mouse_Postnatal brains (at P16)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01827
Perturb_11666_KD_PTBP1_SRP113334	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.13117
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A7LX-01A-12R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K78403457	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25154
BRD-K07567566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.52773
GSE60837_6_v_4_bcl9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
glaucoma	HPO Gene-Disease Associations	1.0	null
GTEX-R3RS-0008-SM-48FF1	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01163
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
GSE127790_6_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CPCN	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58042
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.09707
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3622b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
abnormal telencephalon morphology	MPO Gene-Phenotype Associations	1.0	null
Leukodystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.465
tiapride-7362	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE230744,GSE237803_5_v_3_hira_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59027
AE-39-DG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.422842
hypotonia	MPO Gene-Phenotype Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-7754-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE179880_1_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal body weight	MPO Gene-Phenotype Associations	1.0	null
JUN-26020271-SMOOTH-MUSCLE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K72792753	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54219
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB1-F2del_3Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.77182
BRD-K26306512	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34931
Prostate adenocarcinoma_PRAD_TCGA-EJ-A65E-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
parabigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.847041
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP1	ENCODE Transcription Factor Targets	1.0	null
HCC827GR5	DepMap CRISPR Gene Dependency	1.0	4.78119
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.27889
inferior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.89993
PHC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40372
UTP14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08796
hsa-miR-545	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
peroxisome localization	GO Biological Process Annotations 2015	1.0	null
underdeveloped supraorbital ridges	HPO Gene-Disease Associations	1.0	null
hsa-miR-590-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04084
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CORL105_LUNG	CCLE Cell Line Proteomics	1.0	2.5348
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3387-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organic acid catabolic process	GO Biological Process Annotations 2015	1.0	null
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
stratum lacunosum-moleculare of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.74074
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84499
mefenamic acid-1863	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SPSB1	Hub Proteins Protein-Protein Interactions	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A216-11A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32453
hsa-miR-642b	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
GSE81796_0_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
rhizomelic chondrodysplasia punctata	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.15496
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SRF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K37062347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76731
Disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
basolateral amygdaloid nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79917
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057741
BRD-K89175823	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0923
imatinib_homo sapiens_gpl96_gds3045	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hepatic steatosis	MPO Gene-Phenotype Associations	1.0	null
SW48_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	11.5638
Acute Myeloid Leukemia_LAML_TCGA-AB-2810-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
KDM5A	ChEA Transcription Factor Targets	1.0	null
NR2F2_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K13122526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70389
TP63	ChEA Transcription Factor Targets	1.0	null
BRD-K90149465	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77142
PMC5263239-mmc2.xls-SEM_siMLL-AF4-MLL-AF4_gene_targets_with_decrease_in_MLL-AF4_ChIP-seq_signal_2198_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.199
UTP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90841
GSE70883,GSE71179_0_v_1_pbx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NRF1	ENCODE Transcription Factor Targets	1.0	null
496100641_PCx_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.38688
Death In Infancy	DisGeNET Gene-Phenotype Associations	1.0	null
Trypanosomoid form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.34
naringenin-1342	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SIX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K92241728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69767
Mitochondrial fatty acid beta-oxidation multienzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.625
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.34129
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49127
finger	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.42993
GTEX-RU1J-0008-SM-46MV9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91791
CRCGN015_MCF10A.TP53.M_24H:O23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4726
cytoplasmic part	LOCATE Curated Protein Localization Annotations	1.0	null
nervous system phenotype	MPO Gene-Phenotype Associations	1.0	null
MBD4_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE102675_3_v_0_atf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14831
CRCGN015_HEPG2_48H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.4542
NCIH28	DepMap CRISPR Gene Dependency	1.0	2.19682
BRD-K31483891	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8112
M059K	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47269
single-organism metabolic process	GO Biological Process Annotations 2015	1.0	null
RAD21_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4775	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE209973_1_v_0_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.252919
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-494	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
YY1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PU-27001747-CHIP-SEQ-BMDM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13395
response to reactive oxygen species	GO Biological Process Annotations 2025	1.0	null
PMC7829553__F3	PFOCR Pathway Figure Associations 2024	1.0	null
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2603
GTEX-WYVS-0006-SM-3NMA7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846749
abnormalities of the peripheral arteries	GWASdb SNP-Phenotype Associations	1.0	0.211473
TTLL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39741
Medial amygdalar nucleus, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74841
BRD-K88590066	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82011
generalized abnormality of skin	HPO Gene-Disease Associations	1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.115
EST1-17652178-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
NR2C2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.989964
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5552-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.894127
Gustatory areas, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21159
Micronuclei, Chromosome-Defective	CTD Gene-Disease Associations	1.0	1.22404
ZC3H11A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
peroxisomal part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K19523047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49101
BRD-K56799639	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01339
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.49109
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27457
MAFK	ENCODE Transcription Factor Targets	1.0	null
PRDM14	ChEA Transcription Factor Targets	1.0	null
Infantile Refsum Disease (Disorder)	DisGeNET Gene-Disease Associations	1.0	null
PRDM14-21183938-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12842
aplasia/hypoplasia involving the skeleton	HPO Gene-Disease Associations	1.0	null
GSE81796_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
abnormality of facial soft tissue	HPO Gene-Disease Associations	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JM-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
microbody	LOCATE Predicted Protein Localization Annotations	1.0	null
496100621_TCx_probable Alzheimer's disease_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.79995
BATF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.971581
BRD-K76450502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04775
MCF7_MLN8054_1µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0113561
ventromedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23532
TAF1_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rhombomere 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23009
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Rod-Cone Dystrophy	DisGeNET Gene-Disease Associations	1.0	null
abnormality of the globe	HPO Gene-Disease Associations	1.0	null
PMC6887651-Table_1.xlsx-Sheet1-SRY_SRY	Rummagene Transcription Factor Associations 2026	1.0	null
mRNA_DLX3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K70537701	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28782
pex14p	GeneRIF Biological Term Annotations	1.0	null
GTEX-U3ZN-0226-SM-3DB8D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3819
GSE236437_0_v_3_aldosterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table6_gnomAD_EUR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
adrenal insufficiency	HPO Gene-Disease Associations	1.0	null
hsa-miR-550b	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11397
primary visual cortex (striate cortex, area V1/17)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.998005
FOXA1	ENCODE Transcription Factor Targets	1.0	null
high forehead	HPO Gene-Disease Associations	1.0	null
ABCD3	Pathway Commons Protein-Protein Interactions	1.0	null
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TE4	CCLE Cell Line Gene Expression Profiles	1.0	1.36789
Down Syndrome_CNS - Brain - Cerebellum (MMHCC)_GSE1611	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.35325
Lung adenocarcinoma_LUAD_TCGA-05-5428-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
t60-adrenal_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.15732
Paramedian lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.99914
NELFE	ENCODE Transcription Factor Targets	1.0	null
NFYB	ENCODE Transcription Factor Targets	1.0	null
NCIH1838	CCLE Cell Line Gene CNV Profiles	1.0	1.3421
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.897492
FOXA1	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EGR1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU1J-0326-SM-46MUM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39146
GTEX-SUCS-0726-SM-4DM7J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03633
GTEX-P78B-0008-SM-48TE1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21109
bewo	HPA Cell Line Gene Expression Profiles	1.0	1.00646
abnormality of the gastrointestinal tract	HPO Gene-Disease Associations	1.0	null
A-Netherlands-602-2009(H1N1)_36Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.4622
Peroxisomal disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
GTEX-SIU7-1126-SM-2XCDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19946
znf217_22593193_mda_mb_231_gof_human_gpl570_gse35511	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.566329
GSE127790_10_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
sodium phenylbutyrate-363	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
external ear malformation	HPO Gene-Disease Associations	1.0	null
BRD-K30467307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30535
GSE225218_2_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Liver Failure	DisGeNET Gene-Disease Associations	1.0	null
GABPA_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Inclusion Body Myositides_Muscle tissue_GSE3112	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.6748
17009876-tableS1a	GeneSigDB Published Gene Signatures	1.0	null
integral component of peroxisomal membrane	GO Cellular Component Annotations 2015	1.0	null
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.907199
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE88819_3_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Fallopian Tube	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.4708
Post-translational protein modification	Reactome Pathways 2024	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TAF7_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
GSE226249_2_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Retinal dystrophy with leukodystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.244
PMC7829553__F3	PFOCR Pathway Figure Associations 2023	1.0	null
MET_knockdown_254_GSE38343	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	0.796685
hsa-miR-3647-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
BICR18	CCLE Cell Line Gene CNV Profiles	1.0	2.35964
GTEX-RM2N-1626-SM-2TF5N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869165
GSTM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24366
DB-21-FY25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.209662
MKN74	CCLE Cell Line Gene Expression Profiles	1.0	2.92733
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ataxia	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16665
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE242290_3_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE163862_0_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
DPP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30477
USP7	Hub Proteins Protein-Protein Interactions	1.0	null
Malformations Of Cortical Development	DisGeNET Gene-Disease Associations	1.0	null
Primary somatosensory area, lower limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.63898
primary auditory cortex (core)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.874267
abnormality of blood and blood-forming tissues	HPO Gene-Disease Associations	1.0	null
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Piriform-amygdalar area, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40639
cellular response to oxidative stress	GO Biological Process Annotations 2023	1.0	null
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.840223
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EH-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1299	DepMap CRISPR Gene Dependency	1.0	2.55069
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Trachea	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Uvula (IX), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54688
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.861677
protein import into peroxisome matrix, translocation	GO Biological Process Annotations 2023	1.0	null
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PRDM1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K05135707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70331
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTBP2	ENCODE Transcription Factor Targets	1.0	null
GTEX-XMD1-0011-R3B-SM-4AT5R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06445
NCI-H2347	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.837194
KYSE270	DepMap CRISPR Gene Dependency	1.0	2.069
Telomere cap complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.039
hsa-miR-548g	TargetScan Predicted Conserved microRNA Targets	1.0	0.348832
growth/size/body phenotype	MPO Gene-Phenotype Associations	1.0	null
BRD-K05068331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80775
PMC10702478-jci-133-161348-s262.xlsx-High_targets8listes_TPM_DE-List_of_high_confidence_targets_of_PPAR_genes_regulated_after_18h_in_Mo_by_PA_PPARA	Rummagene Transcription Factor Associations 2026	1.0	null
H3K79me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
T98G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
CBX3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF2_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1HY-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.985776
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletal dysplasia	HPO Gene-Disease Associations	1.0	null
YK-4-279	DeepCoverMOA Drug Mechanisms of Action	1.0	0.88
BRD-K07988588	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48934
496100578_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.37487
PK-45P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
REST_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:A14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.70498
MacAB-TolC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.633
RERFLCSQ1	DepMap CRISPR Gene Dependency	1.0	2.56376
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC3470785-NIHMS377161-supplement-3.pdf-35-CDX2_CDX2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60941
H3K4ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Cortical endoplasmic reticulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.851
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.896897
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H4K20me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.64323
MCF7_BMS-536924_1µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0110775
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.044
BRD-K10761381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46606
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5973-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.046
BRD-K93339508	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.68526
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07791
GTEX-XOTO-0011-R8A-SM-4B65J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07398
H3K4me3_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE244072_4_v_6_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4774-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.265648
Prostate adenocarcinoma_PRAD_TCGA-G9-6351-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nystagmus	DisGeNET Gene-Phenotype Associations	1.0	null
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A97G-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
growth delay	HPO Gene-Disease Associations	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YT-0326-SM-32PKA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829447
abnormal renal/urinary system morphology	MPO Gene-Phenotype Associations	1.0	null
displacement of the external urethral meatus	HPO Gene-Disease Associations	1.0	null
shell of SCH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45308
JUN-27471255-CHONDROCYTES-MOUSE-RIB	ChEA Transcription Factor Targets 2022	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7183-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.51749
HNF4A	ENCODE Transcription Factor Targets	1.0	null
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.60545
SNUC5	DepMap CRISPR Gene Dependency	1.0	2.69136
BRD-K06308228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29803
POLR2A_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4060771-170289.f1.pdf-555-GATA3_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44303
TMEM43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17866
SRF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.012
Lung adenocarcinoma_LUAD_TCGA-50-5066-02A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-CA-04-2009(H1N1)_24Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.32528
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
NFYB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K41089262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36236
SCC4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75177
EP300_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
karpas707	HPA Cell Line Gene Expression Profiles	-1.0	-1.16794
PMC7488531-13287_2020_1914_MOESM10_ESM.xlsx-HNF4A_regulated_DEGs_750-Unnamed_1_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-6647-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT3-24763339-IMN-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN015_MCF10A.TP53.M_24H:I07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.21305
abnormality of the integument	HPO Gene-Disease Associations	1.0	null
abnormality of the oral cavity	HPO Gene-Disease Associations	1.0	null
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.25777
BRD-K28932860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39782
pyloric stenosis	HPO Gene-Disease Associations	1.0	null
Folium-tuber vermis (VII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.05482
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of metabolism/homeostasis	HPO Gene-Disease Associations	1.0	null
2792_EXOSC5_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.546018
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7644-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE110524_2_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
WC-09-GD62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.268643
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10347
GTEX-OXRK-1326-SM-3NB1A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917988
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47719
BRD-K11027431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24764
Organelle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
H3K9ac_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K18533510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.73179
intermediate stratum of r3BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00492
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer IIIb of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02531
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75181
Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KO-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02327
WF-96-ME07_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211548
SRF_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7789-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HUPT3	DepMap CRISPR Gene Dependency	1.0	2.53649
ChIP_KLF4_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Mathematical Ability	DisGeNET Gene-Phenotype Associations	1.0	null
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
BRD-K66494817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.4102
Upward Slant Of Palpebral Fissure	DisGeNET Gene-Phenotype Associations	1.0	null
vomeralnasalorgan.VMO.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.01636
EGR1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gastrointestinal stromal tumor_Gastric Tissue_GSE15966	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.20924
thickened skin	HPO Gene-Disease Associations	1.0	null
BRD-K89584810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23365
LCLC-103H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21057
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09347
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_AICAR_1µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0164256
plicamycin_homo sapiens_gpl570_gse25127	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ChIP_ASH2L_23239880	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.605306
cefotetan-1319	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
r2 part of vestibular nucleus Y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07492
cellular response to oxygen-containing compound	GO Biological Process Annotations 2025	1.0	null
ZNF217_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE183251_1_v_5_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OC-71-BZ81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.240356
PMC11474056-pnas.2404841121.sd01.xlsx-Supplemental_Table_8_Fig1G-H-Supplemental_Table_8_Transcriptomic_overlap_between_LPS_and_Sepsis_and_or_Tuberculosis_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
K562_SGI-1776 free base_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0225072
BRD-K18074484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20081
PATU8902	DepMap CRISPR Gene Dependency	1.0	4.51967
Lateral ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.216
H3K36me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0011-R7B-SM-4B64R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01128
Lung adenocarcinoma_LUAD_TCGA-50-6597-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the choroid	HPO Gene-Disease Associations	1.0	null
malformation of the heart and great vessels	HPO Gene-Disease Associations	1.0	null
GSE114690_2_v_3_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SRF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE157594_0_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4420-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.923483
carbachol-5342	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE234340_12_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE178292_0_v_2_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
RCOR1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBJ-1626-SM-2I3F7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08916
CCT7	Pathway Commons Protein-Protein Interactions	1.0	null
TUBB2B	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-548n	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
P63-26484246-CHIP-SEQ-KERATINOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K39379715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10865
Lung adenocarcinoma_LUAD_TCGA-78-7633-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE144838_4_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pip2-Oaf1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.9
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4274	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
STAT3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventricular septal defect	HPO Gene-Disease Associations	1.0	null
SP4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.853
EST1-17652178-JURKAT-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Developmental and epileptic encephalopathy 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
PMC9174260-41467_2022_30960_MOESM6_ESM.xlsx-S4-RAS1_unique_GATA2-CELSR2_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
FOXP3	ChEA Transcription Factor Targets	1.0	null
GTEX-X261-0126-SM-3NMD6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85084
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17622
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN010_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03335
ELF1	ENCODE Transcription Factor Targets	1.0	null
BRD-K56119660	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40616
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
phenotypic abnormality	HPO Gene-Disease Associations	1.0	null
LB771HNC	DepMap CRISPR Gene Dependency	1.0	2.4569
624 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.19757
PPARG-20176806-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Abnormality Of The Outer Ear	DisGeNET Gene-Disease Associations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-7771-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K65005459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43571
NCI-H187	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H358	GDSC Cell Line Gene Expression Profiles	1.0	1.65796
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
microbody part	GO Cellular Component Annotations 2015	1.0	null
TUBB3	Pathway Commons Protein-Protein Interactions	1.0	null
periventricular stratum of the VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10764
WA-03-IF37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.236616
Submedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24867
USF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
glyoxysome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.404415
BCL3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.987661
Verteporfin_A-427	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0069277
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A54R-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TSE9-0011-R7A-SM-3DB7P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00558
BRD-K95501793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30547
MXI1	ENCODE Transcription Factor Targets	1.0	null
Small intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.016
glycosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.11123
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE57871_8_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5982
BRD-K43108627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20043
microbody	LOCATE Curated Protein Localization Annotations	1.0	null
BRD-K95871937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01661
beta-escin-2194	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.147094
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal iris pigmentation	HPO Gene-Disease Associations	1.0	null
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Heart Defects, Congenital	CTD Gene-Disease Associations	1.0	1.04352
Dwarfism	DisGeNET Gene-Disease Associations	1.0	null
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4579
thp1	HPA Cell Line Gene Expression Profiles	-1.0	-1.95115
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.870241
BRD-K95852319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.59839
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table8_gnomAD_AFR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of the middle ear	HPO Gene-Disease Associations	1.0	null
ZNF784	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9931
hsa-miR-554	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
medial (fastigial) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01801
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of fontanelles	HPO Gene-Disease Associations	1.0	null
Cardiac Arrhythmia	DisGeNET Gene-Phenotype Associations	1.0	null
abnormal muscle tone	HPO Gene-Disease Associations	1.0	null
EGR1	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_7786_KD_RRP40_SRP043962	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.42227
BC-63-DM76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.23681
ELF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.25
TAF7L-23326641-C3H10T1-2-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE126345_9_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CEBPB_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inner CP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38688
TEAD4_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
case	GeneRIF Biological Term Annotations	1.0	null
inner SZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01077
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7407-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
LXR-22158963-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
EW8	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57328
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5835-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A57536034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2415
CNIH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16627
ESO26	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.12454
rt4	HPA Cell Line Gene Expression Profiles	1.0	2.16663
GTEX-OXRO-0011-R2A-SM-3NB1W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55598
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A5W6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
basointermediate isthmic reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10774
GSE191174_0_v_1_ccdc92_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Abnormal Behavior	DisGeNET Gene-Phenotype Associations	1.0	null
abnormal nervous system electrophysiology	HPO Gene-Disease Associations	1.0	null
abnormal conjugate eye movement	HPO Gene-Disease Associations	1.0	null
GTEX-X261-0011-R10B-SM-4E3JT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.931694
Pyramus (VIII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.89892
GTEX-R45C-0008-SM-48FF2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51362
496100582_HIP_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.14325
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051837
GSE125014_1_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE146074_10_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DLD-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.59638
BRD-K79322550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01805
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07371
D341MED	CCLE Cell Line Gene Expression Profiles	-1.0	-1.7846
Mammary Neoplasms, Animal	CTD Gene-Disease Associations	1.0	1.07696
SHP77	CCLE Cell Line Gene CNV Profiles	1.0	1.53297
Peroxisomal protein import	Reactome Pathways 2024	1.0	null
JAK2_activemutant_72_GSE21842	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.53837
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A85H-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K21483524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.9771
GSE206400_3_v_2_nusinersen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KMRC20	DepMap CRISPR Gene Dependency	1.0	4.17399
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.54156
BRD-K93008833	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61283
UACC62	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.57492
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18895
SUZ12_DEPLETION_GDS2445_119_human_embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
blast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070475
hsa-miR-646	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
H3K14ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ETS1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table7_gnomAD_AMR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5507-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
10029_ZC3H8_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.663286
abnormal external genitalia	HPO Gene-Disease Associations	1.0	null
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
abnormality of adrenal physiology	HPO Gene-Disease Associations	1.0	null
GSE232223_1_v_0_letmd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
Blepharoptosis	DisGeNET Gene-Disease Associations	1.0	null
ETS1	ENCODE Transcription Factor Targets	1.0	null
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.08885
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lipid modification	GO Biological Process Annotations 2015	1.0	null
REST_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R53T-1826-SM-3GIJX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08651
H3K27ac_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-3662	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
GSE203158_5_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K08141534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04303
KPL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.35889
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.7438
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.129
GSE157594_5_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE111102,GSE111105_4_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K10284009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.23308
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Retinitis Pigmentosa_Retina_GSE128	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.55973
10755_NON-TARGETING_NON-TARGETING	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.525043
Peroxisomal biogenesis disorder	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
Lung squamous cell carcinoma_LUSC_TCGA-43-3920-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BC3C	CCLE Cell Line Gene CNV Profiles	-1.0	-1.86899
kidney	HPA Tissue Protein Expression Profiles	-1.0	-0.921465
PUR1	MotifMap Predicted Transcription Factor Targets	1.0	null
TestisGermCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.16214
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
H2BK12ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-4718	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GTEX-WFG7-2226-SM-3GIKP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01632
GSE198826,GSE198911_1_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.978848
938_BUD31_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.505601
abnormal myelination	HPO Gene-Disease Associations	1.0	null
Lysosomal storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.189
17676974-TableS1	GeneSigDB Published Gene Signatures	1.0	null
BRD-K85865817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06756
Cortical amygdalar area, posterior part, lateral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.67776
SIRT6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
muscle phenotype	MPO Gene-Phenotype Associations	1.0	null
abnormality of the cerebrum	HPO Gene-Disease Associations	1.0	null
BRD-K56618252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46998
NHEK	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.12881
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.835256
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.979822
GSE154081_3_v_0_sildenafil_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE201309_1_v_7_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17825
brompheniramine-1335	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.08943
HUCCT1	DepMap CRISPR Gene Dependency	1.0	4.02314
BRD-K71496240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03422
Perturb_15517_KD_E2F2_SRP314859	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.10971
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.06251
strabismus	HPO Gene-Disease Associations	1.0	null
Neural stem cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.699
Spinal Muscular Atrophy, Infantile_CNS - Spinal Cord (MMHCC)_GSE3075	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.08651
HT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.79826
BRD-K33438042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41522
GTEX-QVJO-1426-SM-2S1QY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.859859
GTEX-U8XE-1726-SM-4E3IF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32994
GTEX-UTHO-0011-R4A-SM-3GIJP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16081
PMC8087671__F2	PFOCR Pathway Figure Associations 2024	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45X-01A-21R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dinoprost	DeepCoverMOA Drug Mechanisms of Action	1.0	0.44
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
icSARA deltaORF6_7Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.06621
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.22397
ELK1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K77345736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19071
Central amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03844
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
LONP2	Pathway Commons Protein-Protein Interactions	1.0	null
living	GeneRIF Biological Term Annotations	1.0	null
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
iopamidol-2732	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_36_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K73290515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51953
GATA2-21186366-BM-HSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
isthmic roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16925
GTEX-S4P3-0008-SM-3NM8R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15606
PMC4777381-pone.0150624.s007.xlsx-dif_exp_AD-ZBTB38_ZBTB38	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OXRL-0008-SM-3NB29	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918557
lateropallial amygdalopiriform area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.50777
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36677
BRD-K08806664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20935
intrinsic component of peroxisomal membrane	GO Cellular Component Annotations 2015	1.0	null
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21324
neuron migration	GO Biological Process Annotations 2023	1.0	null
BRD-K39962926	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43142
Infection by Yersinia enterocolitica_macrophage_GSE2973	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.25858
COQ7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09448
Subparaventricular zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16482
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01535
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
movement of cell or subcellular component	GO Biological Process Annotations 2015	1.0	null
GAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13456
BRD-K29366596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20991
Malabsorption, Ctcae	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K27035180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27061
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16966
Musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.571
HC-01-FD24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.225657
Brain Lower Grade Glioma_LGG_TCGA-DU-7304-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tetraethylenepentamine-457	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEx Heart 20-29 vs 40-49	GTEx Tissue-Specific Aging Signatures	-1.0	-3.08919
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GA-88-CF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.209835
NCIH2196	CCLE Cell Line Gene CNV Profiles	-1.0	-2.08084
KALS1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52604
isthmic alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45057
fatty acid catabolic process	GO Biological Process Annotations 2023	1.0	null
GSE198434_1_v_0_aspirin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68816
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95546
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.78949
PBX3	ENCODE Transcription Factor Targets	1.0	null
GTEX-R53T-1126-SM-48FD4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12002
GTEX-Q2AG-0011-R9A-SM-2HMJ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03067
SIX5_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K89501960	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30059
bounding membrane of organelle	GO Cellular Component Annotations 2015	1.0	null
BRD-K57323824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62665
GTEX-S95S-0002-SM-3NM8K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0671
GSE173810_4_v_1_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A113-11A-12R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACSBG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07536
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10704
organelle	GO Cellular Component Annotations 2015	1.0	null
KDM6A	ChEA Transcription Factor Targets	1.0	null
hypertonia	HPO Gene-Disease Associations	1.0	null
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAWR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13426
BRD-K42081955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4805
estropipate-2506	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ARH77	DepMap CRISPR Gene Dependency	1.0	4.63743
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Spleen	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.29263
hsa-miR-3152-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
GSE135030_3_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZMIZ1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
decreased body size	MPO Gene-Phenotype Associations	1.0	null
KP1N	DepMap CRISPR Gene Dependency	1.0	2.17554
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47X-01A-31R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCL2L12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02524
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.012
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
HS294T	CCLE Cell Line Gene Expression Profiles	-1.0	-2.01368
GSE202434,GSE202438_15_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A1OC-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Reduced Tendon Reflexes	DisGeNET Gene-Phenotype Associations	1.0	null
PMC5058748-oncotarget-07-31177-s002.xlsx-ZNF224_gene_peaks_promoter-Table_S3_Genes_that_contain_a_ZNF224_enriched_region_within_1_kb_of_the_transcription_ZNF224	Rummagene Transcription Factor Associations 2026	1.0	null
PRDM14-21183938-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
SW 900	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.83646
GTEX-S32W-1926-SM-4AD63	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11952
YY1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
aphagia	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K11585900	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21882
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-199b-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.17031
PDCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5852
uterus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.077833
RAD21_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organelle localization	GO Biological Process Annotations 2015	1.0	null
Feeding Difficulties	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-WFJO-0008-SM-4LVN7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31588
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65578
Peroxisomal importomer complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Brain Lower Grade Glioma_LGG_TCGA-DU-5847-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149264,GSE149267_2_v_1_trp53_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.37414
SOX7_OE_GDS3300_123_human_HESC (CA1 and CA2)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-P44H-0011-R4A-SM-2XCEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.997799
cryptorchidism	HPO Gene-Disease Associations	1.0	null
Perturb_16585_KO_Bmal1_SRP217335	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.91068
cognitive impairment	HPO Gene-Disease Associations	1.0	null
Photoreceptor inner segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.727
GTEX-QDVN-0008-SM-48U2D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15988
Chromosomal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.001
visceromegaly	HPO Gene-Disease Associations	1.0	null
regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
pcgf2_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.216042
BRD-K70183558	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00242
Primary somatosensory area, lower limb, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22418
KLF4-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
abnormal respiration	MPO Gene-Phenotype Associations	1.0	null
17880687-TableS1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46379
SG in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.850149
H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Peroxisome biogenesis disorder 11B	ClinVar Gene-Phenotype Associations	1.0	null
GTEX-OHPN-0011-R3A-SM-2I5FC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04464
Unspecified Visual Loss	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K68512873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0745
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
mantle zone of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17076
XRN2-22483619-HELA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BC-72-DZ30_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.306782
abnormal retinal pigmentation	HPO Gene-Disease Associations	1.0	null
K562_Mesna_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0172973
periventricular stratum of AStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.83369
MAFF	ENCODE Transcription Factor Targets	1.0	null
GSE141726,GSE141733_1_v_0_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Electroencephalogram Abnormal	DisGeNET Gene-Phenotype Associations	1.0	null
PARP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31298
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10X-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056823
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09773
BRD-K21059010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26578
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AQ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
SIN3A_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
liver	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-F2-A44G-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
glucose metabolism disease	GWASdb SNP-Disease Associations	1.0	0.262771
abnormal total tissue mass	MPO Gene-Phenotype Associations	1.0	null
periventricular stratum of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50099
BRD-K94751306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.02051
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
danazol-5315	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-69-A59K-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K27982554	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19536
SP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34277
NR2C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05261
YY1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral parabrachial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.834797
artery disease	GWASdb SNP-Disease Associations	1.0	0.097397
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RAD21_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
KMH2	CCLE Cell Line Gene CNV Profiles	1.0	2.07738
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ebolavirus(EBOV)_2day_PBMCs_17725815_GSE8317	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.85756
GSE94011_0_v_3_pias3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lobule III, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78393
BRD-K35668999	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00544
PRDM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28219
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
mantle zone of AStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62829
disrupted	GeneRIF Biological Term Annotations	1.0	null
Copula pyramidis, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23639
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.48537
RPL23A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91427
LIVF001-011	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.54566
GTEX-QMR6-0011-R4A-SM-32PKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.869729
SP4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CF-50-QK79_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201521
granule cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.275794
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27924
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q9-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05182
Posterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07707
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-CoV MA15_Day7-PFU-10^5_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.68584
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.54387
MSC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1746
PAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28707
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD19 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-4795-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.37496
meteneprost-7552	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.52893
BRD-K38692266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13843
BICR 22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.849238
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.442
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC12245139-Supplementary_material-Suppl.2-s2.xlsx-Table_S4_AR_transmission-Unnamed_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
FOXA2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NPEPPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75389
GSE223609,GSE223610_0_v_1_kdm6a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-181b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
CRCGN008_HEPG2_24H:I20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.022
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2GZ-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNMC-0008-SM-4DM5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49132
GTEX-RNOR-0011-R7A-SM-2TF4V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42783
BRD-K12325488	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49955
PC-87-OG75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.487088
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36432
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.41486
Rough endoplasmic reticulum membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.117
cell motility	GO Biological Process Annotations 2015	1.0	null
abnormality of the abdominal organs	HPO Gene-Disease Associations	1.0	null
NR2F2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AGPS	Pathway Commons Protein-Protein Interactions	1.0	null
7608_RUVBL2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.536955
PABPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.004
NCI-H1092	GDSC Cell Line Gene Expression Profiles	-1.0	-1.66821
arrhythmia	HPO Gene-Disease Associations	1.0	null
H3K9ac_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DA-20-VR86_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.289036
ctnnb1_21565795_adrenocortical_adenomas_lof_mouse_gpl570_gds3912	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.057059
HT	DepMap CRISPR Gene Dependency	1.0	4.78468
GSE87404,GSE87812_1_v_0_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4762-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.085563
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.446939
H3K79me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE124920_1_v_2_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H4K8ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TAF7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59885
abnormal mitochondrial crista morphology	MGI Mouse Phenotype Associations 2023	1.0	null
icSARA deltaORF6_60Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.53923
Skin Cutaneous Melanoma_SKCM_TCGA-GF-A769-01A-32R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K62504352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05436
GSE131649_2_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PEX5	Pathway Commons Protein-Protein Interactions	1.0	null
FAM167B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01379
H3K4me1_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
7389_RNF34_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.650249
Formate dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.784
Brain - Nucleus accumbens (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	1.0	1.44477
POLR2AphosphoS5_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRKAR2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15784
GTEX-QMRM-0726-SM-2I5G8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10532
H3K4me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTF2F1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K27067020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03189
GABPA_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K68731395	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56454
GSE199255,GSE199356_4_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal hepatobiliary system morphology	MPO Gene-Phenotype Associations	1.0	null
H4K5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K05444553	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19151
H3K27ac_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Basolateral amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.70817
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K79me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XLM4-0011-R2B-SM-4AT5Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16894
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1236	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
BRD-K35188988	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45683
dactinomycin_mus musculus_gpl6246_gse21233	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FB-39-CW59_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.333557
ATF3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WHSC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ERAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12226
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
abnormal renal morphology	HPO Gene-Disease Associations	1.0	null
NAPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5844
Hand1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.9407
Crohn's disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.001
PBX3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE183251_1_v_0_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KDM6A-18722178-U937-AND-SAOS2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
abnormality of movement	HPO Gene-Disease Associations	1.0	null
BRD-K46291400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28828
Lung adenocarcinoma_LUAD_TCGA-69-7979-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF12_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r2 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22137
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE217115_3_v_0_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:A07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0768
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EK-01A-12R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
behavior/neurological phenotype	MPO Gene-Phenotype Associations	1.0	null
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K04992384	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6436
dentate (lateral) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.918287
GSE158834_2_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9794594-DataSheet_1.xlsx-ST12-Unnamed_6_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XV7Q-1126-SM-4BRVS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38881
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.135
Lung squamous cell carcinoma_LUSC_TCGA-18-3414-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF3-18347094-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Motor neuron disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.039
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3883
NFATC1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostatic Hyperplasia	CTD Gene-Disease Associations	1.0	1.09401
AKT2_knockdown_44_GSE12291	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.91662
abnormality of the supraorbital ridges	HPO Gene-Disease Associations	1.0	null
H3K27ac_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.955597
BRD-K21955645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14332
syndrome	GeneRIF Biological Term Annotations	1.0	null
BRD-K13076765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06482
GSE169356_0_v_4_ivermectin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GATA3_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63905
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XOTO-0011-R9A-SM-4GICI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12772
BRD-K34405227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.09448
GSE199538,GSE199539_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
JUND_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
myb_16205643_primary_monocytes_gof_human_gpl570_gse2816	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.102133
Seizures	DisGeNET Gene-Phenotype Associations	1.0	null
6552_POLR2K_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.574429
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.377738
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.2187
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
BT-20	GDSC Cell Line Gene Expression Profiles	1.0	3.35175
MV411	CCLE Cell Line Gene Expression Profiles	-1.0	-1.9077
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_1_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
lissencephaly	HPO Gene-Disease Associations	1.0	null
abnormality of the palpebral fissures	HPO Gene-Disease Associations	1.0	null
G-402	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.926499
hsa-miR-3647-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.389112
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11518
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_BRD4770_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.013366
GTEX-RU72-0011-R2A-SM-2TF6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42253
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K02388444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61711
NMC-G1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.8452
GSE158834_11_v_8_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CA-10-RU23_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.304456
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.941836
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.835508
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3X1-01A-12R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5887
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.890463
BRD-K47951404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0952
erythroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.181488
PU.1-20513432-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
protein import into peroxisome matrix, translocation	GO Biological Process Annotations 2025	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-8359-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HELA	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.26593
GTEX-WFG7-0008-SM-4LMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851969
H3K27ac_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03864
GTEX-S4UY-0008-SM-3NM8H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4808
U-698-M	GDSC Cell Line Gene Expression Profiles	1.0	1.52972
LC-1F	GDSC Cell Line Gene Expression Profiles	1.0	2.16208
abnormal forebrain morphology	MPO Gene-Phenotype Associations	1.0	null
salivarygland_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.885944
Ascospore wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.74
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.972544
CRCGN015_MCF10A_48H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.75385
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.35827
H3K27ac_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
abnormal breathing pattern	MPO Gene-Phenotype Associations	1.0	null
FOSL2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
parataenial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21506
Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08796
GTEX-N7MT-1926-SM-3LK5N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37765
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11629026-VMS3-11-e70074-s003.xlsx-SRY-Gene_name_SRY	Rummagene Transcription Factor Associations 2026	1.0	null
Abnormality Of The Tongue	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-U3ZM-0008-SM-4DXTQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48838
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.903
Muscle Hypotonia	DisGeNET Gene-Phenotype Associations	1.0	null
CCT6A	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K32943057	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22706
PMC6941881-mmc4.xlsx-IR_only_Up_DEGs-List_of_DEGs_that_are_upregulated_upon_PRMT5_KD_only_in_IR_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
respiratory tract infection	HPO Gene-Disease Associations	1.0	null
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.954621
abnormality of the nares	HPO Gene-Disease Associations	1.0	null
Vesicular gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.198
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
coronary artery disease	GWASdb SNP-Disease Associations	1.0	0.5757
CREB1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BC-56-CP81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.563731
BE-38-UW72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.284109
tranylcypromine-7293	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TestisIntersitial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
Integumentary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.164
abnormal bone structure	HPO Gene-Disease Associations	1.0	null
TRIM28	ENCODE Transcription Factor Targets	1.0	null
GSE211151_1_v_4_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
TUBB4B	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN015_HEPG2_48H:F15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.17775
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE223008_7_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142210_4_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PML	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-3607-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KR-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VPS45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47139
hsa-miR-548k	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
REST_PFSK-1_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AB-84-PK04_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.46695
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
white matter of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49999
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29881
microbody	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Autoimmune disease of gastrointestinal tract	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.012
abnormal palmar dermatoglyphics	HPO Gene-Disease Associations	1.0	null
BRD-K15975627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.08125
Rectum adenocarcinoma_READ_TCGA-G5-6572-02A-12R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal survival	MPO Gene-Phenotype Associations	1.0	null
COV434	CCLE Cell Line Gene Expression Profiles	1.0	1.68867
2792_EXOSC5_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.617978
aminophylline-6295	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BHLHE40_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-HS-A5NA-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K61431055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24003
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3163	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
abnormality of nervous system morphology	HPO Gene-Disease Associations	1.0	null
17483311-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
H3K9ac_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-64-1678-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
failure to thrive	HPO Gene-Disease Associations	1.0	null
hindbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.09007
H3K4me1_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE234340_10_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GATA3-21867929-CD8-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
TCF3	ENCODE Transcription Factor Targets	1.0	null
GSE158834_7_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RNOR-0011-R4A-SM-3GAD3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00883
GTEX-QEL4-0726-SM-3GIJ5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956767
Leukemialymphoblastic(MOLT-4)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.25476
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7SE-0011-R2A-SM-2XCDC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07467
abnormality of muscle morphology	HPO Gene-Disease Associations	1.0	null
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08624
malabsorption	HPO Gene-Disease Associations	1.0	null
hsa-miR-433	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
motor nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.96791
GTEX-WHPG-0226-SM-3NMB9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943509
Nucleus taeniae	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.66
GSE235390_4_v_0_lurbinectedin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KYSE270	CCLE Cell Line Gene Expression Profiles	-1.0	-2.08053
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRIM28_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-dORF6_12Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.62594
BRD-K70109334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22238
GSE156505_1_v_0_dis3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K16727544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09609
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
PMC7265888__AF2	PFOCR Pathway Figure Associations 2023	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7317-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fatty acid oxidation	GO Biological Process Annotations 2023	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SJ-01A-12R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
response to reactive oxygen species	GO Biological Process Annotations 2023	1.0	null
medial parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04281
CHD1-26751641-CHIP-SEQ-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K75416889	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15081
BRD-K20624967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2516
fetal ultrasound soft marker	HPO Gene-Disease Associations	1.0	null
CCDC127	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16047
HA7-RCC	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.36145
integral component of peroxisomal membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-QEG4-0008-SM-48TYZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909154
FOXM1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.26578
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43202
BRD-K91628074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41896
type 2 diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.612357
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12179407-MCO2-6-e70261-s004.xlsx-down_TET3-KO_PQ_vs_Cas9_PQ-Unnamed_10_TET3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC4515549-NIHMS63168-supplement-3.xlsx-1B_HNF4A-reg_genes_post-treat-GeneSymbol_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K00414849	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0979
IRF3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.005295
BRD-K70412800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12971
MYBL2-22936984-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
morantel-1676	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CB 13	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.37
GTEX-OHPN-0011-R11A-SM-2I5FM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.927059
eGFP-GATA2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Multicystic Dysplastic Kidney	DisGeNET Gene-Disease Associations	1.0	null
disease of metabolism	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-4662a-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QV-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
apnea	HPO Gene-Disease Associations	1.0	null
LOXIMVI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ERMES complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.289
BRD-K15647573	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53363
Skin fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.007
endocrine/exocrine gland phenotype	MPO Gene-Phenotype Associations	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.12
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MAFF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-766	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Procyclic form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.807
abnormality of the ear	HPO Gene-Disease Associations	1.0	null
abnormality of the urethra	HPO Gene-Disease Associations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5516-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cns hypomyelination	HPO Gene-Disease Associations	1.0	null
BRD-K12384030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43645
abnormality of the nasal bridge	HPO Gene-Disease Associations	1.0	null
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNF4A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_24H:O07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01921
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61743
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93855
Oligospermia	CTD Gene-Disease Associations	1.0	1.11809
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.96054
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-0011-R7a-SM-2HMJV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.854897
abnormal mitochondrial morphology	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K14144134	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47727
Cvt vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.627
UACC257	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62003
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS944T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57599
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRRX2	JASPAR Predicted Transcription Factor Targets	1.0	null
Male inflorescence	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.616
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chorioretinal abnormality	HPO Gene-Disease Associations	1.0	null
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Intrinsic component of peroxisomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.922
RBBP5	ENCODE Transcription Factor Targets	1.0	null
Bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.16
Uterine Carcinosarcoma_UCS_TCGA-NF-A5CP-01A-12R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IKZF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETS1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
4108_IMP4_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.537783
abnormal peripheral nervous system morphology	HPO Gene-Disease Associations	1.0	null
TAF1_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3ac_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE167886_2_v_0_chd7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebral cortex cell migration	GO Biological Process Annotations 2025	1.0	null
Hydrogenosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.891
single-organism process	GO Biological Process Annotations 2015	1.0	null
mantle zone of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38512
methylprednisolone-1567	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE210885_0_v_7_klf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
trochlear nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.989143
Pancreatic adenocarcinoma_PAAD_TCGA-L1-A7W4-01A-12R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HT	CCLE Cell Line Gene Expression Profiles	-1.0	-2.06624
abnormality of male external genitalia	HPO Gene-Disease Associations	1.0	null
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17938
BRD-K24453679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35031
Perturb_14232_Mut_Dpagt1_SRP230444	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	13.3688
BRD-K05831864	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28048
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Cerebellum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47399
GABPA	ENCODE Transcription Factor Targets	1.0	null
PAX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7125-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
arm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.375368
GTEX-TSE9-0011-R9A-SM-3DB7Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26578
MCF7_Mocetinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00904385
GATA6-25053715-YYC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
abnormality of the genital system	HPO Gene-Disease Associations	1.0	null
DETROIT562	CCLE Cell Line Gene Expression Profiles	1.0	1.90542
GSE121809_1_v_0_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Glyoxysomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.987
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_161_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.78751
FLI1-21867929-TH2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HSD17B4	Pathway Commons Protein-Protein Interactions	1.0	null
translocon complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.308494
REST_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.216
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01013
CREB1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral hypothalamic area, anterior part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12195
Neoplasm Metastasis	CTD Gene-Disease Associations	1.0	1.35906
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CHD1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNOS-1126-SM-4DM67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59549
tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04859
Brain Lower Grade Glioma_LGG_TCGA-FG-5964-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TKQ1-0003-SM-3NMAE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04845
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.85614
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.995081
GTEX-PWO3-0926-SM-2I5EY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03494
cellular response to reactive oxygen species	GO Biological Process Annotations 2023	1.0	null
shell part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2332
hand	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.428783
GSE131377_1_v_0_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.18259
neonatal lethality, complete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
EP300_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K40103182	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60527
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.404386
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A4-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_Tubastatin A HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0152446
GSE114258_3_v_2_foxk1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.853822
H3K4me1_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05429
GSE118077_7_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.030095
BRD-K27858225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0728
cell part	GO Cellular Component Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-8158-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal cell morphology	MPO Gene-Phenotype Associations	1.0	null
SMAD4	ChEA Transcription Factor Targets	1.0	null
SRF_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1734	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.894127
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A3DL-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GB-46-CK08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.550304
abnormality of the upper limb	HPO Gene-Disease Associations	1.0	null
PML_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0011-R8a-SM-2YUMK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828318
Autosomal recessive disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the nervous system	HPO Gene-Disease Associations	1.0	null
MYB	ENCODE Transcription Factor Targets	1.0	null
GTEX-X261-0011-R6B-SM-4E3J8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25091
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SEC24D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01992
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNF4A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE182727_1_v_0_busulfan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NFIC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
9547_UBR4_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.639864
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13167
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.46618
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCL3	ENCODE Transcription Factor Targets	1.0	null
BRD-K95508535	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.90426
abnormality of the nose	HPO Gene-Disease Associations	1.0	null
sc11	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.947
MC-40-IP75_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.522614
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.454898
TCF12_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Organelle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.408
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XXEK-0826-SM-4BRWG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33725
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
neurodevelopmental delay	HPO Gene-Disease Associations	1.0	null
NCIH2196	CCLE Cell Line Gene Expression Profiles	-1.0	-3.50911
basolateral amygdaloid nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35104
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GSE148010,GSE148120_3_v_2_tet2_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Endoplasmic reticulum exit site	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.8
EXOC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23294
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.66962
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAX6-23342162-BETA-FORBRAIN-LENS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Retinitis pigmentosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.082
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21093
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50946
Hepatitis	CTD Gene-Disease Associations	1.0	1.04794
Rough endoplasmic reticulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.888
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.867937
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K25877713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61464
PMC8709578-elife-69843-supp4.xlsx-HSF1_ChIP-seq_peaks-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A110-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K28565184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19628
Infertility, Female	CTD Gene-Disease Associations	1.0	1.14644
EBF1	ENCODE Transcription Factor Targets	1.0	null
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040506
functional abnormality of the inner ear	HPO Gene-Disease Associations	1.0	null
GSE236454,GSE236456_0_v_1_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
amygdaloid complex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14343
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
magnocellular superficial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01921
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0914
PMC7870953-41540_2021_169_MOESM9_ESM.xlsx-RREB1_targets-target_gene_RREB1	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.05748
multi-organism process	GO Biological Process Annotations 2015	1.0	null
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.9257
hsa-miR-216a	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC7518873-abb0205_Table_S1.xls-TFEB_targets-symbol_TFEB	Rummagene Transcription Factor Associations 2026	1.0	null
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.954621
BCLAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-601	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.867937
EGR1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.87305
KP-N-YS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32847
GTEX-XXEK-1126-SM-4BRUX	GTEx Tissue Sample Gene Expression Profiles	1.0	3.27351
VZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0731
GSE196699_4_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE114690_1_v_0_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
brushfield spots	HPO Gene-Disease Associations	1.0	null
PAX6-23342162-BETA-FORBRAIN-LENS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
adrenal gland	HPA Tissue Protein Expression Profiles	1.0	1.02714
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3358-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
telencephalon cell migration	GO Biological Process Annotations 2023	1.0	null
GSE202434,GSE202438_4_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
abnormal mitochondrial physiology	MGI Mouse Phenotype Associations 2023	1.0	null
organelle membrane	GO Cellular Component Annotations 2015	1.0	null
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Intrinsic component of mitochondrial outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.933
arteriosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.235694
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE202434,GSE202438_12_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7592-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE211286_7_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.935241
glycosome lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.18338
BRD-K69914820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74222
GTEX-T6MN-0011-R9A-SM-32QOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03048
HCFC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXM1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ansiform lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4787
NR2C2	ENCODE Transcription Factor Targets	1.0	null
ZNF728	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18172
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.94745
hs27	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.996
RELA_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2795-01A-02R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00545
H3K4me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
IGROV1	BioGPS Cell Line Gene Expression Profiles	1.0	0.931344
TEF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7187
GW7647	DeepCoverMOA Drug Mechanisms of Action	1.0	0.27
lateral hemisphere of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08237
Extrinsic component of organelle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.516
WC-09-GD62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.223783
thickened nuchal skin fold	HPO Gene-Disease Associations	1.0	null
abnormal epiphyseal ossification	HPO Gene-Disease Associations	1.0	null
H3K4me3_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PC-14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HNF1A	Pathway Commons Protein-Protein Interactions	1.0	null
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.850013
PMC9992472-41467_2023_36735_MOESM7_ESM.xlsx-SOX11_ChIP_in_IMR-32-Unnamed_12_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
CREB_DEPLETION_GDS3487_41_human_K562 myeloid leukemia cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
abnormality of the posterior segment of the eye	HPO Gene-Disease Associations	1.0	null
BRD-K50443235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72961
CRCGN015_MCF10A_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.7205
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K14987634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31738
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33528
NC-27-AD53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.833166
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K59099886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64111
BRD-K10943878	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40274
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.948825
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-7711-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Microbody membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.54
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01707
CRCGN015_HEPG2_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.74535
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the orbital region	HPO Gene-Disease Associations	1.0	null
CA-16-ZL71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.23301
H3K56ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
19061838-TableS14	GeneSigDB Published Gene Signatures	1.0	null
BRD-K07996284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3179
dorsolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28708
SIRT6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lobules IV-V, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75731
DLD1	BioGPS Cell Line Gene Expression Profiles	1.0	1.71438
neuron degeneration	MGI Mouse Phenotype Associations 2023	1.0	null
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE171837_3_v_2_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE158834_2_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.64833
ABC1	CCLE Cell Line Gene CNV Profiles	1.0	1.63987
GSE158834_2_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
abnormal eating behavior	MPO Gene-Phenotype Associations	1.0	null
periaqueductal gray substance, dorsolateral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13799
FOXA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lipid storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.108
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-548am	TargetScan Predicted Conserved microRNA Targets	1.0	0.020071
protein localization	GO Biological Process Annotations 2025	1.0	null
CRCGN009_HEPG2_24H:K12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.11117
abnormality of brain morphology	HPO Gene-Disease Associations	1.0	null
BRD-K02637850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62458
substantia nigra, pars reticulata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.836409
ovary	HPA Tissue Protein Expression Profiles	-1.0	-0.921465
Microbody	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
FOSL2_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K10781609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56032
abnormality of the musculature	HPO Gene-Disease Associations	1.0	null
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.06315
hsa-miR-3140-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GSE158834_7_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
SB-222200	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.32
peroxisome biogenesis disorder 11b	OMIM Gene-Disease Associations	1.0	null
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93646
NCIH3255	CCLE Cell Line Gene Expression Profiles	1.0	1.51401
ABC-1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.29303
CRCGN015_MCF10A_48H:J03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.05373
TAF1_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
superficial stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18874
GTEX-WL46-0011-R2A-SM-3LK6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20586
A549_Motesanib Diphosphate_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0160123
YY1	ENCODE Transcription Factor Targets	1.0	null
GSE175787_4_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE156115_0_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GABPA_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4793-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
PMC11908325-media-2.xlsx-Table10_MR-Unnamed_7_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
FOSL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.837194
hsa-miR-181c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GSE210655_1_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
OXCT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27285
H3K4me1_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84J-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Microbody	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.034
Tuberomammillary nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01606
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1212
Purkinje cell layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36532
EP300_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K30292003	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10445
BRD-K59006776	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05444
hsa-miR-195	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.39874
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70Q-01A-13R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KA-81-AG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.248329
Agranular insular area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20149
KDM1A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.957479
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.56405
TestisLeydigCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.42491
vinblastine-7517	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RS411	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49784
GTEX-XOTO-0011-R5A-SM-4B657	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0553
Disease Models, Animal	CTD Gene-Disease Associations	1.0	1.13552
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the urinary system	HPO Gene-Disease Associations	1.0	null
BRD-K75135426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69275
CRCGN017_MCF10A.WT.HP_24H:P08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.49575
17483311-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
PMC11749115-loae020_suppl_Supplementary_Table_S2.xlsx-CHOP-high-gene_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.14618
Microbody membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
organelle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.430253
BRD-K71561082	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91352
BRD-K52190624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3794
Rectum adenocarcinoma_READ_TCGA-DY-A1DG-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Poisoning	CTD Gene-Disease Associations	1.0	1.45883
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_49_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
SRF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Malabsorption	DisGeNET Gene-Phenotype Associations	1.0	null
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71795
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
forebrain cell migration	GO Biological Process Annotations 2015	1.0	null
prostate	HPA Tissue Gene Expression Profiles	1.0	1.3079
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057716
Central lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.73578
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0695
supporting cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.223662
cisapride-2443	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
JURKAT, CLONE E6-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
FC-13-VS25_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.31857
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.911485
DVL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03363
BRD-K34677894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0969
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	2.04319
Lung adenocarcinoma_LUAD_TCGA-86-8054-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sec62/Sec63 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.977
ELL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14057
Tirofiban	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.24
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.62756
BRD-K00907050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31068
abnormality of the upper urinary tract	HPO Gene-Disease Associations	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
SARS-CoV_48Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.77648
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Abnormality Of Coagulation	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-S4Q7-0926-SM-4AD5D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845317
GSE146074_1_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Liver	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HIV - Human immunodeficiency virus infection_T lymphocyte_GSE6740	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.61232
MAFK_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:F17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.398
CEBPB_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-MES-1	GDSC Cell Line Gene Expression Profiles	-1.0	-2.31712
GTEX-WYJK-1626-SM-3NM9J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05761
abnormality of the skull	HPO Gene-Disease Associations	1.0	null
SETDB1_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE230174_0_v_1_dagla_human	RummaGEO Gene Perturbation Signatures	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.724
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0011-R3A-SM-4B64W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843037
Acute Myeloid Leukemia_LAML_TCGA-AB-2984-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
copper sulfate-459	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE138019_3_v_6_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal podocyte morphology	MPO Gene-Phenotype Associations	1.0	null
NCIH1355	DepMap CRISPR Gene Dependency	1.0	2.9909
Brain_Hippocampus_Middle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.97311
KLC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13824
pancreas_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.31632
TRIM28_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PEX3	Pathway Commons Protein-Protein Interactions	1.0	null
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.643
AB-71-CI37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.377103
H4K8ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE222758_0_v_4_clofazimine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12713692-mpa-55-e82-s009.xlsx-HNF1A__vs_Ctrl-Gene_Name_HNF1A	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ECI2	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN015_MCF10A_48H:F10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.45792
posterior embryotoxon	HPO Gene-Disease Associations	1.0	null
reduced tendon reflexes	HPO Gene-Disease Associations	1.0	null
amygdaloid complex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.35827
hsa-miR-199a-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.17031
GATA3_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1395	CCLE Cell Line Gene CNV Profiles	1.0	1.36812
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052751
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB2-627E_18Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.67541
Nuclear telomere cap complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.041
abnormality of the kidney	HPO Gene-Disease Associations	1.0	null
JUN_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Multiple Renal Cysts	DisGeNET Gene-Disease Associations	1.0	null
Adult_Liver	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.959092
PSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54945
BCLAF1	ENCODE Transcription Factor Targets	1.0	null
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K67319345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10012
Inherited metabolic disorder	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
CAL-120	COSMIC Cell Line Gene Mutation Profiles	1.0	null
prepontine hindbrain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24973
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletal muscle atrophy	HPO Gene-Disease Associations	1.0	null
Crus 1, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42803
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13188
POLR2A_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MT-0011-R7a-SM-2I3FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.966305
YY1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of higher mental function	HPO Gene-Disease Associations	1.0	null
abnormality of the iris	HPO Gene-Disease Associations	1.0	null
CREB1-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
cervical intraepithelial neoplasia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.36496
SP4	ENCODE Transcription Factor Targets	1.0	null
posteroventral (inferior) parietal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.96252
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYBL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-02A-21R-A36H-07,TCGA-DU-6404-02B-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMAD3-18955504-HaCaT-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPU-0011-R9A-SM-3NM8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53902
SIRT6	ENCODE Transcription Factor Targets	1.0	null
small molecule catabolic process	GO Biological Process Annotations 2015	1.0	null
hsa-miR-499a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GSE202434,GSE202438_15_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Trypanosomoid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.569
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4017
IV, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.14927
ZE-45-CG69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.221877
GTEX-XGQ4-2026-SM-4AT6G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86477
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29835
BRD-K34590335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07345
Taurine dioxygenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.697
GABPA_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal muscle tone	MPO Gene-Phenotype Associations	1.0	null
PMC12183081-41388_2025_3375_MOESM8_ESM.xlsx-Sheet1-Table_S7_List_of_differentially_alternative_splicing_genes_in_osteosarcoma_cell_lines_after_knocking_down_the_YBX1_gene_P_0_05_Related_to_Fig_6C_YBX1	Rummagene Transcription Factor Associations 2026	1.0	null
inner SZ in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.919768
PPP6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79151
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K30558628	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1608
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.26337
PADI4-21655091-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE214212_2_v_1_chd6_human	RummaGEO Gene Perturbation Signatures	1.0	null
HDGFL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24128
abnormality of the adrenal glands	HPO Gene-Disease Associations	1.0	null
BRD-K38558166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18456
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.6905
abnormality of the cranial nerves	HPO Gene-Disease Associations	1.0	null
MAX_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DNM1L	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.867937
striatal amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62962
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.26179
PRKACA_knockout_266_GSE20984	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.46405
THP1	DepMap CRISPR Gene Dependency	1.0	3.40053
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
epidermal thickening	HPO Gene-Disease Associations	1.0	null
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.86257
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.897954
CRCGN015_MCF10A.TP53.M_24H:N11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10115
ETS1-20019798-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
abnormal cortical gyration	HPO Gene-Disease Associations	1.0	null
BB-11-JI42_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208661
GSE112763,GSE112767_4_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.66856
JUND_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100636_FWM_probable Alzheimer's disease_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01506
Byzanthine Arch Palate	DisGeNET Gene-Disease Associations	1.0	null
DAUDI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HDAC1	ENCODE Transcription Factor Targets	1.0	null
SIN3A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.41906
TCF12_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ichthyosis	HPO Gene-Disease Associations	1.0	null
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44725
FNTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32731
AE-13-CX28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.271213
GSE79291_1_v_2_streptozotocin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
norfloxacin-7283	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T5JC-0008-SM-4DM6A	GTEx Tissue Sample Gene Expression Profiles	1.0	2.20847
peroxisomal matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.85045
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Adipose - Visceral (Omentum)	GTEx Tissue Gene Expression Profiles 2023	1.0	1.77853
POLR2A_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.841946
ZR751	CCLE Cell Line Gene Expression Profiles	1.0	1.35338
HCC1195	CCLE Cell Line Gene CNV Profiles	1.0	1.43835
Drug-Related Side Effects and Adverse Reactions	CTD Gene-Disease Associations	1.0	1.19933
itself	GeneRIF Biological Term Annotations	1.0	null
BRD-K45734531	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06158
GB-73-QS80_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.213088
ATF2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3691-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
peroxisome	GO Cellular Component Annotations 2025	1.0	null
MCRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10964
GTEX-QDVN-0826-SM-48TZ2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11317
GTEX-XMD1-0011-R2B-SM-4AT5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45426
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835938
amygdaloid complex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.30113
GSE155162,GSE155169_1_v_2_buparlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXP3-21729870-TREG-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH2023	DepMap CRISPR Gene Dependency	1.0	2.98928
cerebellar cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.42633
ribavirin_homo sapiens_gpl570_gds4391	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K24292260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39118
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09939
abnormality of forebrain morphology	HPO Gene-Disease Associations	1.0	null
BRD-K59847773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38441
colon	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.05586
GSE143782_6_v_5_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOXC11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0188
Entorhinal area, lateral part, layer 2b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16262
abnormal eye physiology	HPO Gene-Disease Associations	1.0	null
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9208
ZBTB33	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8667
BRD-K66941670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97945
CRCGN017_MCF10A.WT.HP_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.65715
seminal vesicle	HPA Tissue Protein Expression Profiles	1.0	1.02714
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.8746
HCC1500	CCLE Cell Line Gene CNV Profiles	-1.0	-1.9736
KLM1	CCLE Cell Line Gene Expression Profiles	1.0	1.73324
BRD-K61223323	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95773
abnormality of head or neck	HPO Gene-Disease Associations	1.0	null
H3K18ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K93130549	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40926
lipid metabolic process	GO Biological Process Annotations 2015	1.0	null
USF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TTC1	Pathway Commons Protein-Protein Interactions	1.0	null
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lipid catabolic process	GO Biological Process Annotations 2015	1.0	null
intrinsic component of peroxisomal membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
microbody membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.34283
Postpiriform transition area, layers 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.35103
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K00509345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3555
IRF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWO3-0011-R2A-SM-2S1OX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21579
ZNF143	ENCODE Transcription Factor Targets	1.0	null
GTEX-OOBJ-2126-SM-3NB1N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834162
egg	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.227445
ZEB1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE198380_0_v_1_phgdh_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4307	TargetScan Predicted Conserved microRNA Targets	1.0	0.389112
Perturb_7785_KD_MTREX_SRP043962	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.64623
Central amygdalar nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10042
generation of neurons	GO Biological Process Annotations 2023	1.0	null
hepatomegaly	HPO Gene-Disease Associations	1.0	null
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.927
TRIM28_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
central gray of the pons, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.40503
CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.901934
CHD7_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U4B1-1126-SM-4DXV3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22757
hsa-miR-548f	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
Oocyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.755
19723343-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
GSE205729,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.92612
primary adrenal insufficiency	HPO Gene-Disease Associations	1.0	null
A-61603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29726
E3 ubiquitin ligases ubiquitinate target proteins	Reactome Pathways 2024	1.0	null
NTAQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20831
GTEX-U412-0008-SM-4DXTE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22373
hsa-miR-508-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
retroparafascicular area of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.73812
lambdoid septal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25589
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K19526797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20786
FOSL2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K38972344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26294
abnormality of skull size	HPO Gene-Disease Associations	1.0	null
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19395
RC-K8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24392
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE188870,GSE188871_1_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12056
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80V-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUND_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K22189231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44273
protein import into peroxisome matrix	GO Biological Process Annotations 2025	1.0	null
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.919689
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.048215
FAM193B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0573
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.891788
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65706
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16112
GSE212299_2_v_1_abi3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS5_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100608_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0407
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0211
BRD-K13087600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45499
hecogenin-2716	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
adrenoleukodystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.57913
GTEX-OXRO-0011-R9A-SM-3NB1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.881518
mantle zone of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30091
NCIH2291	DepMap CRISPR Gene Dependency	1.0	3.40085
BRD-K00542622	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32728
red nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.874649
GSE157555,GSE157556_5_v_6_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01381
Genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
Peroxisome Biogenesis Disorder	DisGeNET Gene-Disease Associations	1.0	null
SOX2-30713093-EPITHELIAL-HUMAN-TONGUE-SCC	ChEA Transcription Factor Targets 2022	1.0	null
BB-86-BE39_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214749
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-181d	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Lens disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
Perinuclear endoplasmic reticulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.898
TAL1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEL	DepMap CRISPR Gene Dependency	1.0	4.83858
TUBB4A	Pathway Commons Protein-Protein Interactions	1.0	null
Amniocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.872
hsa-miR-4461	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
TE11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34017
GTEX-S3XE-1526-SM-4AD5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09078
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRCA1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
eeg abnormality	HPO Gene-Disease Associations	1.0	null
hsa-miR-383	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14869
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.72
GTEX-UTHO-1826-SM-3GAFE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856677
CRCGN017_MCF10A.TP53.M_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.04387
primary auditory cortex (core)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.15073
BRD-K61020385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34006
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7872-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GC-04-UF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.299987
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.633169
eGFP-HDAC8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K72681425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01877
behavioral abnormality	HPO Gene-Disease Associations	1.0	null
decreased body weight	MGI Mouse Phenotype Associations 2023	1.0	null
GSE165916_1_v_2_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cortex of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43099
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRN-0011-R5A-SM-2I5EF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831865
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K58112932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14604
BRD-K55538850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38442
abnormality of the calvaria	HPO Gene-Disease Associations	1.0	null
PEX16	Pathway Commons Protein-Protein Interactions	1.0	null
RPS6KA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19098
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.992017
NCIH82	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47614
Adenocarcinoma	CTD Gene-Disease Associations	1.0	1.12495
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN008_HEPG2_24H:O18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7984
ELF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30808
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ATF3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51G-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BB-64-EE60_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.375172
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926638
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Abnormality Of Retinal Pigmentation	DisGeNET Gene-Phenotype Associations	1.0	null
central medullary reticular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.888556
JE-04-LS32_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.249633
red nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00886
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cdx2_21074721_jejunum_epithelium_lof_mouse_gpl10773_gse23436	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.53554
POLR2A_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6994-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-1.81219
AA-86-YY62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.349034
Anemia	CTD Gene-Disease Associations	1.0	1.10769
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.377738
BRD-K03916755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.73516
Fat body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.008
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.026159
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983693
Glaucoma	DisGeNET Gene-Disease Associations	1.0	null
GSE183251_4_v_0_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T8EM-0006-SM-3DB71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56489
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PWCY-0008-SM-48TE9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28866
superficial stratum of r2BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22137
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.2676
Adrenoleukodystrophy	DisGeNET Gene-Disease Associations	1.0	null
BRD-K25877330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10226
plastid-encoded plastid RNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.511
CREM-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
liver/biliary system phenotype	MPO Gene-Phenotype Associations	1.0	null
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00741
PMC7746852__F3	PFOCR Pathway Figure Associations 2023	1.0	null
GTEX-OIZG-1126-SM-2HMIU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826228
GSE229468,GSE229471_0_v_1_znf587_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1028
697	DepMap CRISPR Gene Dependency	1.0	4.14023
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.90705
MEF2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsal thalamus_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.866458
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF7	ENCODE Transcription Factor Targets	1.0	null
Norwalk Virus_HG23_19515767_GSE15520	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.59624
icSARA deltaORF6_3Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.55984
Lung adenocarcinoma_LUAD_TCGA-69-7764-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r4 part of pontine raphe cell population	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02011
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05837
testis_7b	HPA Tissue Sample Gene Expression Profiles	1.0	0.969443
TAF1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44424
GSE210225_0_v_1_inosine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Inferior olivary complex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.83
SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15021
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR2C2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal facial shape	HPO Gene-Disease Associations	1.0	null
hsa-miR-4269	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
CF-24-KQ98_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.312057
hsa-miR-577	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
p92	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.974
MCF7_Veliparib_1µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0144149
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5899
4149_INTS4_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.569813
GSE88819_0_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
BRD-K13225050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6036
regional abnormality of skin	HPO Gene-Disease Associations	1.0	null
TAF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
localization	GeneRIF Biological Term Annotations	1.0	null
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EBC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53759
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841469
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
17724462-TableS1	GeneSigDB Published Gene Signatures	1.0	null
liver	HPA Tissue Protein Expression Profiles	-1.0	-0.921465
AD-55-WK61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205313
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
abnormal respiratory system physiology	MPO Gene-Phenotype Associations	1.0	null
163 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.805
marrow cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07468
GTEX-QV44-2026-SM-2S1RD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09233
BRD-K37165790	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16084
GSE240344_1_v_0_uxs1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ATF3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Peroxisome biogenesis disorder	ClinVar Gene-Phenotype Associations 2025	1.0	null
Flat Face	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K21449711	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3383
Male infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
Skin fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.447
Ocular albinism with sensorineural deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.204
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5957
CTCF_GM12864_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11502753-41467_2024_53330_MOESM11_ESM.xlsx-Sheet1-SMAD3_target_genes_hES_SMAD3	Rummagene Transcription Factor Associations 2026	1.0	null
cellular phenotype	MPO Gene-Phenotype Associations	1.0	null
BRD-K05070188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02149
hsa-miR-15b	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
Facial Paralysis	DisGeNET Gene-Disease Associations	1.0	null
GTEX-POMQ-0008-SM-48TE7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40941
GSE130401_4_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
yolk sac	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.396465
NCIH1666	CCLE Cell Line Gene Expression Profiles	1.0	1.58845
hsa-miR-197	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
BRD-K25709301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17387
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_476_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
STAT5A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.50459
BRD-K97487406	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18174
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSDMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12876
NELFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85368
BRD-K80066561	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0875
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P44H-0011-R1A-SM-3NM8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.906553
A4-Fuk	GDSC Cell Line Gene Expression Profiles	-1.0	-2.92259
NR2F2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11071
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09245
FOXI1	JASPAR Predicted Transcription Factor Targets	1.0	null
layer II of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08185
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VL-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202434,GSE202438_4_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Ursodiol	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.3
H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
liver_d	HPA Tissue Sample Gene Expression Profiles	1.0	1.05108
LY-294002-424	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-RVPV-0011-R5A-SM-2TF69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26946
arsenic trioxide_homo sapiens_gpl201_gse48441	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DPEP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1571
abnormal adrenal cortex morphology	MPO Gene-Phenotype Associations	1.0	null
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.936
sc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.883
CALU-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07305
PMC9675280-12950_2022_317_MOESM2_ESM.xlsx-LPS_vs_control-Unnamed_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U3ZH-0008-SM-4DXT2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898474
testis_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.11575
Endoplasmic reticulum subcompartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.815
MYC_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940428
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.939117
ar_21330406_lncap_lof_human_gpl570_gds4113	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.661368
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CA-72-JV60_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205459
RASGRF1_KD_GDS2816_287_human_Hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE227698_2_v_1_g0s2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Breast	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.016
hearing impairment	HPO Gene-Disease Associations	1.0	null
hsa-miR-425	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
KAT2A	ENCODE Transcription Factor Targets	1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1205	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Autoimmune disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.012
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75476
GABPA_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Profound Global Developmental Delay	DisGeNET Gene-Disease Associations	1.0	null
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
GTEX-OHPM-2626-SM-33HC5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04835
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.22696
CUX1	ENCODE Transcription Factor Targets	1.0	null
abnormality of the neck	HPO Gene-Disease Associations	1.0	null
caudal presubiculum (postsubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.078
Necrosis	CTD Gene-Disease Associations	1.0	1.72779
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4340-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6363-01A-21R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE168807_0_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
valproic acid-458	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
fatty acid catabolic process	GO Biological Process Annotations 2025	1.0	null
reticulotegmental nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.954099
NCIH2126_LUNG	CCLE Cell Line Proteomics	1.0	2.66415
BRD-K61704278	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85588
Polymicrogyria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.556
PMC12515692-MOL2-19-2882-s005.xlsx-Proteome_AKT1_AKT2_KD_vs_SCR-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE143782_3_v_4_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K03654379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03205
BRD-K06792661_Narciclasine_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE214442_0_v_1_pak4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A-CA-04-2009(H1N1)_18Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.8996
Nasal Bridge Wide	DisGeNET Gene-Phenotype Associations	1.0	null
FOXA1-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-OOBK-0008-SM-3NB27	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18508
BRD-K02920459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94794
GTEX-SIU8-0426-SM-4BRUE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848158
NR2C2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K23923189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35363
peroxisomal disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
H3K27ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
thyroid	GTEx Tissue Gene Expression Profiles	1.0	0.934366
valproic acid_mus musculus_gpl1261_gds3002	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN008_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.789
POLR2AphosphoS2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QLQ7-0726-SM-2I5G2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.07071
GTEX-R53T-0526-SM-3GADL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14047
CEBPD_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA-73-BW50_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.226668
NCIH2141	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74331
H3K9ac_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Cortical amygdalar area, posterior part, medial zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10281
adiposetissue	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.27925
TET1-21490601-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Autosomal recessive nonsyndromic deafness 59	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.112
GSE158834_10_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-193a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE158834_7_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
EAPP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1474
Hematopoietic stem cell_Bone marrow_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
GSE201877_1_v_0_yap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
nod2_21335489_hek293_lof_human_gpl570_gds4416	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.036173
SARS-BatSRBD_48Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.4752
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_3_TurboID_1hr_ERM_proteome-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
MELJUSO	DepMap CRISPR Gene Dependency	1.0	3.15157
CRCGN016_MCF10A.TP53.M_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.02331
skin_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.06812
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA3_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K86467057	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.26567
GD-73-ZF64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.231038
HL60	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.97664
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TJ-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EB-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5814
eGFP-JUNB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor-sensory cortex (samples)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.945576
sin3a_22783022_mcf7_lof_human_gpl570_gds4388	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.909136
GTEX-XK95-0008-SM-4AT5G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86187
central hypotonia	HPO Gene-Disease Associations	1.0	null
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36785
abnormal pyramidal signs	HPO Gene-Disease Associations	1.0	null
periventricular stratum of r2Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07492
CRCGN012_HEPG2_24H:C02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.40245
BRD-K19344710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13668
Cortical amygdalar area, anterior part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47329
BRD-K17889110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11445
H4K20me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KA-29-AB08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.285524
large face	HPO Gene-Disease Associations	1.0	null
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2BK5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Ulcerative colitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.012
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE164874_5_v_3_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB157	CCLE Cell Line Gene CNV Profiles	1.0	1.40898
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60868
H3K4me1_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SRF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE131649_4_v_7_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RU72-0011-R7A-SM-2TF5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25226
CRCGN015_MCF10A.TP53.M_24H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.20049
abnormality of the face	HPO Gene-Disease Associations	1.0	null
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4963
abnormal muscle physiology	MPO Gene-Phenotype Associations	1.0	null
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46306
OCILY18	DepMap CRISPR Gene Dependency	1.0	2.05434
REST_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12872_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.416
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-1179	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
1716_CNOT1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.634975
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6351-01A-21R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCH	DepMap CRISPR Gene Dependency	1.0	2.0209
malar anomaly	HPO Gene-Disease Associations	1.0	null
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09033
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
Adrenoleukodystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.717
GABPA_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052133
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41621
Polymicrogyria	DisGeNET Gene-Disease Associations	1.0	null
PANC0813	CCLE Cell Line Gene Expression Profiles	1.0	1.70823
hsa-miR-2052	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
suckling behavior	GO Biological Process Annotations 2025	1.0	null
GTEX-XLM4-3026-SM-4AT6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940113
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.928144
NFATC1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cotyledon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.063
BRD-A61014366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23516
PDCD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36035
Hydronephrosis	DisGeNET Gene-Disease Associations	1.0	null
BRD-K38706080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19094
hippocampus (hippocampal formation)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.824364
Autosomal recessive spinocerebellar ataxia 25	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.034
GSE247775_1_v_0_tmprss2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chromosome, telomeric repeat region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.039
Feeding Difficulties In Infancy	DisGeNET Gene-Phenotype Associations	1.0	null
substantia nigra, pars compacta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1239
ZNF217	ENCODE Transcription Factor Targets	1.0	null
POU5F1-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
A549_Cediranib_1µM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0139205
EF-74-KW12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.248327
Rectum adenocarcinoma_READ_TCGA-G5-6572-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Duchenne muscular dystrophy (DMD)_Extraocular muscle_GSE1008	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.25463
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17526
GTEX-U8T8-0008-SM-4DXSP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54274
BRD-K00955582	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56366
KLF4-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Tricuspid Valve Stenosis	DisGeNET Gene-Disease Associations	1.0	null
H3K27ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K92701606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09973
GSE147613_1_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.50264
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	2.89902
optic atrophy	HPO Gene-Disease Associations	1.0	null
TCF12_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.94077
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.94745
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.012
budesonide-6330	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SBF transcription complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.695
BA-77-US35_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.263496
Congenital nervous system abnormality	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.301
FOXP2_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K05118964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11826
GSE201217_2_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7840052__F7	PFOCR Pathway Figure Associations 2023	1.0	null
subcuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.28105
Adrenoleukodystrophy	CTD Gene-Disease Associations	1.0	2.88009
FA-92-JL46_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.336122
Macrolide transmembrane transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.435
abnormality of neuronal migration	HPO Gene-Disease Associations	1.0	null
micropexophagy-specific membrane apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.594
LC1F	CCLE Cell Line Gene Expression Profiles	1.0	1.74133
GSE125007,GSE125008_1_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16693
GSE57871_11_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
SIX5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nerve Degeneration	CTD Gene-Disease Associations	1.0	1.54718
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZFP36L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0253
parafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.901533
Rhizomelic chondrodysplasia punctata type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.39
A-Netherlands-602-2009(H1N1)_24Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.28147
Apnea	DisGeNET Gene-Phenotype Associations	1.0	null
Lateral amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26539
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23296
GTEX-PWOO-0008-SM-48TDU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09666
PMC10742386-pnas.2311372120.sd05.xlsx-GCM1_EVT-Gene_Symbol_GCM1	Rummagene Transcription Factor Associations 2026	1.0	null
18667080-TableS9	GeneSigDB Published Gene Signatures	1.0	null
GSE242290_3_v_2_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
Muscle Weakness	DisGeNET Gene-Phenotype Associations	1.0	null
TCF12_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
depressed nasal bridge	HPO Gene-Disease Associations	1.0	null
BRD-K18179332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38625
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
18310505-TableS6	GeneSigDB Published Gene Signatures	1.0	null
triangular face	HPO Gene-Disease Associations	1.0	null
SP1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-PC-A5DP-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.318817
MYC	ENCODE Transcription Factor Targets	1.0	null
15897907-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
ASH2L-23239880-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
regulation of catabolic process	GO Biological Process Annotations 2015	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8410-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.24181
H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6849
GSE164463_4_v_1_pax6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S3XE-0008-SM-3NM8O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23323
SOCS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31373
GTEX-X4XY-1726-SM-46MVO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83631
TUBA4A	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K27050140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17548
TA-34-CK62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.24613
hsa-miR-509-3-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
MAFK_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZN-0008-SM-4DXTL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03061
GTEX-QLQ7-0008-SM-447AW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15303
MYOG	ENCODE Transcription Factor Targets	1.0	null
intracellular part	GO Cellular Component Annotations 2015	1.0	null
Cerebellar cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54141
H3K36me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.56459
regulation of mitochondrion organization	GO Biological Process Annotations 2015	1.0	null
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46834
Neuronal cell body membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.655
SIX5_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K78886448	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46027
COLO800	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47985
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Peroxisomal membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
vegetative cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.335968
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6329
GTEX-OHPN-0011-R1A-SM-2I5GB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24916
GTEX-OOBJ-2626-SM-2I3F6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25239
NCIH2141	CCLE Cell Line Gene Expression Profiles	-1.0	-1.95584
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4307	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
small molecule metabolic process	GO Biological Process Annotations 2015	1.0	null
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
testis_7e	HPA Tissue Sample Gene Expression Profiles	1.0	1.52082
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXM1	ENCODE Transcription Factor Targets	1.0	null
BRD-K22839533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33254
BRD-K56470219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.22712
TCF7L2_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12871_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05207
SHSYSY-RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.983558
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.01336
abnormality of eye movement	HPO Gene-Disease Associations	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.27114
GSE198165,GSE198166_0_v_1_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.442795
MICA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75712
PMC7829553__F2	PFOCR Pathway Figure Associations 2024	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
GSE185944_2_v_3_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
pedunculo(pontine) tegmental  nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05883
GTEX-T2IS-0011-R2A-SM-32QPF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.976448
BRD-K45367466	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.29978
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.966738
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hereditary spastic paraplegia 49	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE160001,GSE160670_0_v_2_lapatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mRNA_RAD21_21589869	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
496100574_HIP_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.70248
salivary gland	HPA Tissue Protein Expression Profiles	1.0	1.02714
BRD-K46334103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6363
GTEX-U3ZM-0526-SM-4DXTB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85841
MAFK_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Respiratory Insufficiency	DisGeNET Gene-Phenotype Associations	1.0	null
KU812	DepMap CRISPR Gene Dependency	1.0	2.42818
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40696
PMC5263239-mmc2.xls-MV4_11_-_MLL-AF4-Non-spreading_targets_gene_names_1985_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K95033255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44402
GATA1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FLT1_knockdown_111_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.92152
BRD-K94088431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.38534
PMC7870953-41540_2021_169_MOESM9_ESM.xlsx-ZNF423_targets-target_gene_ZNF423	Rummagene Transcription Factor Associations 2026	1.0	null
adult stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063853
GTEX-U4B1-1026-SM-4DXT1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61252
hsa-miR-544	TargetScan Predicted Conserved microRNA Targets	1.0	0.37496
abnormal consumption behavior	MPO Gene-Phenotype Associations	1.0	null
YY1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
NFIC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GB-73-QS80_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.317764
abnormal mitochondrion morphology	MPO Gene-Phenotype Associations	1.0	null
Pancreatic Neoplasms	CTD Gene-Disease Associations	1.0	1.08726
PMC9823215-mmc4.xlsx-Sheet1-List_of_genes_commonly_upregulated_by_wild_type_and_zinc_finger_mutant_of_LIN28A_LIN28A	Rummagene Transcription Factor Associations 2026	1.0	null
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	3.04957
GSE214596,GSE214598_1_v_3_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
dolichocephaly	HPO Gene-Disease Associations	1.0	null
BRD-K33606137	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27013
abnormal body composition	MPO Gene-Phenotype Associations	1.0	null
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Glyoxysome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.992
r3 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25081
dlx4_00000000_mcfdash7_gof_human_gpl201_gse21657	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	1.20926
PHF5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41315
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.64296
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TKQ1-0008-SM-4DXSO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60391
hsa-miR-559	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
abnormality of the endocrine system	GWASdb SNP-Phenotype Associations	1.0	0.076654
GTEX-OIZH-2126-SM-3NB1P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67669
2291_DNAJC17_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.650914
MCF10DCIS.COM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.870241
GTEX-X261-0011-R7A-SM-4E3JJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01087
disorder	GeneRIF Biological Term Annotations	1.0	null
CRCGN016_MCF10A.WT.HP_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.71011
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VP-A87J-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rhizomelic chondrodysplasia punctata type 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.716
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
metolazone-6292	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenomyeloneuropathy	DisGeNET Gene-Disease Associations	1.0	null
ELK4	ENCODE Transcription Factor Targets	1.0	null
ZNF534	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5065
suckling behavior	GO Biological Process Annotations 2023	1.0	null
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
2789_EXOSC2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.549045
EP300_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K18142082	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11342
Signal recognition particle receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.108
Mammary-luminal epithelial cell of mammary gland	Tabula Sapiens Gene-Cell Associations	1.0	12.0651
Acute Myeloid Leukemia_LAML_TCGA-AB-2835-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE184892_6_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormal renal glomerulus morphology	MPO Gene-Phenotype Associations	1.0	null
ACOT8	Pathway Commons Protein-Protein Interactions	1.0	null
Hearing Impairment	DisGeNET Gene-Phenotype Associations	1.0	null
USF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC3858414-NIHMS492171-supplement-1.pdf-22-OVOL1_OVOL1	Rummagene Transcription Factor Associations 2026	1.0	null
HCFC1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung Neoplasms	CTD Gene-Disease Associations	1.0	1.3827
BRD-K32918816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44217
doxycycline-1113	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Cortical amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28137
rostral presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04817
H3K9ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-R55G-0126-SM-48FDS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97429
H4K91ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kinetoplastid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.833
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12529
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.90679
CE-52-XV55_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211964
abnormality of skeletal morphology	HPO Gene-Disease Associations	1.0	null
Rhizomelic chondrodysplasia punctata type 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.139
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41776
gallbladder	HPA Tissue Protein Expression Profiles	1.0	1.02714
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EGR1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.2726
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-0.925157
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6254
HCFC1	ENCODE Transcription Factor Targets	1.0	null
BRD-K05977380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20006
BRD-K38980456	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1369
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.867937
GSE69869_0_v_1_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Chondrodysplasia punctata	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.6
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29835
PAX5	ENCODE Transcription Factor Targets	1.0	null
GTEX-RM2N-1926-SM-48FCU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26568
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23727
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6988-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XXEK-1326-SM-4BRV1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988942
Respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Hyphal tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.968
Cerebral degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.279
Compound-1a	DeepCoverMOA Drug Mechanisms of Action	1.0	0.33
H3K79me2_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NALM-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.929605
feeding difficulties in infancy	HPO Gene-Disease Associations	1.0	null
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00063
abnormality of the eyelid	HPO Gene-Disease Associations	1.0	null
GSE131649_6_v_7_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.012
abnormality of the midface	HPO Gene-Disease Associations	1.0	null
spleen	HPA Tissue Protein Expression Profiles	-1.0	-2.74743
MYBL2-22936984-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K17285268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43426
roof plate of p2 (epithalamic roofplate)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58243
BE-70-CU78_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202839
GSE199606_1_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE168596_2_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
UA-39-TN76_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.455984
caused	GeneRIF Biological Term Annotations	1.0	null
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.335
Prostate adenocarcinoma_PRAD_TCGA-CH-5789-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Carcinoma, Hepatocellular_Hepatic Tissue_GSE2127	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.38559
BRD-K31218318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45902
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A118-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35187
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.951155
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.615013
Phagophore assembly site	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.912
BC-10-SB73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.206839
SUM185PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.714436
BRD-K14327064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20202
posteromedial cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38488
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TUBA1A	Pathway Commons Protein-Protein Interactions	1.0	null
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZEB1	ENCODE Transcription Factor Targets	1.0	null
BRD-K48900723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.45558
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.998483
TROVE2	Hub Proteins Protein-Protein Interactions	1.0	null
fulvestrant_homo sapiens_gpl570_gse22533	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VAChT_KD_GDS4325_361_mouse_Heart from C57BL/6 males	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
mantle zone of LAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.50777
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MYC_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
APEX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78567
decreased body weight	MPO Gene-Phenotype Associations	1.0	null
zellweger	GeneRIF Biological Term Annotations	1.0	null
abnormal mitochondrial inner membrane morphology	MPO Gene-Phenotype Associations	1.0	null
GSE215351,GSE215794_4_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
nasopharynx	HPA Tissue Protein Expression Profiles	1.0	1.02714
GTEX-Q2AG-2926-SM-2HMJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.834866
SW1783	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC5263239-mmc2.xls-KOPN-8_-_MLL-ENL-Non-spreading_targets_gene_names_1358_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-1243	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
TAF7L	ChEA Transcription Factor Targets	1.0	null
BRD-K35336753	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56239
CRCGN016_MCF10A.TP53.M_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.96611
GTEX-X62O-0008-SM-46MU5	GTEx Tissue Sample Gene Expression Profiles	1.0	2.73853
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-N7MT-0011-R3a-SM-2I3GC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08438
HARA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
deficiency	GeneRIF Biological Term Annotations	1.0	null
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-3.21434
abnormality of the line of schwalbe	HPO Gene-Disease Associations	1.0	null
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATAD1	Pathway Commons Protein-Protein Interactions	1.0	null
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.3982
NELFE_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Vermal regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70653
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
terminal hypothalamus (rostral hypothalamus)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1155
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4684
GTEX-R55C-0626-SM-2TF4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13645
BRD-K13681383	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.4746
cerebellar white matter	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38937
BT549	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40406
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YD-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTF2B	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
IRF1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the mouth	HPO Gene-Disease Associations	1.0	null
M14	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.11807
SUM159PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.2427
AP1S2	ChEA Transcription Factor Targets	1.0	null
Peroxisomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.541
GTEX-WVLH-0011-R7A-SM-3MJFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23508
Nyctalopia	DisGeNET Gene-Disease Associations	1.0	null
Urinary bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.16
PMC3607232-mmc3.xlsx-a_RUNX1_SEM_MLLN_AF4C_H3K79Me-x_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
HDAC6	ENCODE Transcription Factor Targets	1.0	null
11823860-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
GTEX-R55D-0126-SM-48FEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06596
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Compound leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.647
GSE210885_3_v_1_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
layer III of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.78865
renal/urinary system phenotype	MPO Gene-Phenotype Associations	1.0	null
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3864
GTEX-OHPN-0011-R2A-SM-2I5FB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.96413
Zellweger syndrome	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
Ehlers-Danlos syndrome musculocontractural type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.108
CHD2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20Q-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K71604365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45864
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A23L-01A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the external nose	HPO Gene-Disease Associations	1.0	null
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
granular layer of caudal dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.947937
XRN2-22483619-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K21167361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.2395
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.27983
Lung adenocarcinoma_LUAD_TCGA-49-4488-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
microbody	GO Cellular Component Annotations 2015	1.0	null
WHSC1	ENCODE Transcription Factor Targets	1.0	null
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.39826
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
EP300_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22185
DNM2	Pathway Commons Protein-Protein Interactions	1.0	null
abnormality of the penis	HPO Gene-Disease Associations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5522-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the abdomen	HPO Gene-Disease Associations	1.0	null
QE-18-WG07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.469855
9592_UNC45A_P1	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.716643
Chromosome 17q12 duplication syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.354
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.99311
blood	GTEx Tissue Gene Expression Profiles	-1.0	-1.0695
Cell tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.78
CREB1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.00247
IRF4	ENCODE Transcription Factor Targets	1.0	null
locomotion	GO Biological Process Annotations 2015	1.0	null
GSE152937_6_v_5_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K12886565	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67163
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K10010414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26622
RUNX1	ChEA Transcription Factor Targets	1.0	null
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0011-R8A-SM-3P5Z1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873869
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
female pseudohermaphroditism	HPO Gene-Disease Associations	1.0	null
CHO cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.286
Crus 2, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53336
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.19181
POLR2A	ENCODE Transcription Factor Targets	1.0	null
KLM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1837
PK-59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01025
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.205
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brain	GTEx Tissue Gene Expression Profiles	-1.0	-1.43045
GSE148096_1_v_0_erlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7327-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Crus 2, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58184
oxoacid metabolic process	GO Biological Process Annotations 2015	1.0	null
superficial stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21455
microbody membrane	GO Cellular Component Annotations 2023	1.0	null
H3K27ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89428
EIF2S3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7043
Ghost	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.124
Heart Diseases	CTD Gene-Disease Associations	1.0	1.32339
Bone disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.571
Lung adenocarcinoma_LUAD_TCGA-73-4676-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EPHA4_knockout_226_GSE34430	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.19268
cell migration	GO Biological Process Annotations 2015	1.0	null
oxidation-reduction process	GO Biological Process Annotations 2015	1.0	null
GSE185944_5_v_3_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VI	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.870068
hsa-miR-3129-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.09606
NCI-H290	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.94982
Brain Lower Grade Glioma_LGG_TCGA-VV-A86M-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
forelimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.106357
Intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75507
SMC3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
elevated hepatic transaminases	HPO Gene-Disease Associations	1.0	null
urinary bladder	HPA Tissue Protein Expression Profiles	1.0	1.02714
Glycosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.379
CRCGN017_MCF10A.TP53.M_24H:J04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15282
GSE231648_1_v_5_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.87549
GSE158834_12_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
skin fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.912653
CRCGN015_MCF10A.TP53.M_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.31155
abnormality of the fundus	HPO Gene-Disease Associations	1.0	null
18667080-TableS2	GeneSigDB Published Gene Signatures	1.0	null
feeding difficulties	HPO Gene-Disease Associations	1.0	null
type ii diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.519915
Sensorineural Hearing Loss (Disorder)	DisGeNET Gene-Disease Associations	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052289
NCIH1693	CCLE Cell Line Gene Expression Profiles	1.0	1.56169
MAFK_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Crus 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43058
H3K79me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TEAD4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYOG_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bestatin_NCI-H1792	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0160736
cerebellar cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.247079
SP1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
aplasia/hypoplasia affecting bones of the axial skeleton	HPO Gene-Disease Associations	1.0	null
MCF7_ENMD-2076 L-Tartaric acid_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0161907
TAF7L-23326641-C3H10T1-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K39411863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55949
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.881903
abnormal genital system morphology	HPO Gene-Disease Associations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-A5C4-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pallidal amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32042
H3K79me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POU5F1-16153702-HESC-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
GSE231745_1_v_0_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.679376
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.992663
KARPAS-422	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24392
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Peroxisome	KEGG Pathways 2026	1.0	null
regulation of cellular component organization	GO Biological Process Annotations 2015	1.0	null
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3737
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5440-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K40939137	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18613
KNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12798
Postpiriform transition area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.19232
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858102
BRD-K32491833	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47925
GSE196699_2_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
tanespimycin-1225	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
superficial stratum of PHyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01921
GTEX-W5X1-0006-SM-3GIJZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.891201
BRD-K07530355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02504
primary auditory cortex (core)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.97191
Brain Lower Grade Glioma_LGG_TCGA-E1-5304-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal motor capabilities/coordination/movement	MPO Gene-Phenotype Associations	1.0	null
alar part of terminal hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21276
BRD-K27008344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06654
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.43538
abnormality of the seventh cranial nerve	HPO Gene-Disease Associations	1.0	null
Breast Neoplasms	CTD Gene-Disease Associations	1.0	1.41451
GSE183335,GSE183351_3_v_2_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Primary immunodeficiency disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.012
CRCGN015_HEPG2_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.7616
SPI1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRAF3IP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11592
GSE190235_3_v_2_foxo3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZZZ3	ENCODE Transcription Factor Targets	1.0	null
BRD-K33760911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31739
cellular localization	GO Biological Process Annotations 2015	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-515-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
CBM complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.716
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
CRCGN009_HEPG2_24H:C08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14347
r3 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0053
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BHLHE40_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medrysone-3705	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
abnormal neuron morphology	MPO Gene-Phenotype Associations	1.0	null
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Zellweger Syndrome	CTD Gene-Disease Associations	1.0	2.88009
TUBA1B	Pathway Commons Protein-Protein Interactions	1.0	null
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-GATA3_only-Nearest_Ensembl_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210655_1_v_4_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K24259871	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02678
regulation of organelle organization	GO Biological Process Annotations 2015	1.0	null
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03762
IgA immunoglobulin complex, circulating	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.682
Lobule II	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49751
YY1_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF488	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11587
RDES	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60914
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.258917
SNGM_ENDOMETRIUM	CCLE Cell Line Proteomics	1.0	6.17083
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5461-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K06279388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30421
membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
e1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.881
abnormality of female external genitalia	HPO Gene-Disease Associations	1.0	null
5964_LTO1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.576654
ractopamine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.64821
GTEX-T5JW-0008-SM-4DM5X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3629
Vesicle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.653
Infertility, Male	CTD Gene-Disease Associations	1.0	1.17
TAF7_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCT5	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K47238978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6039
KA-71-CQ35_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.367395
GABPA_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CUX1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cortical amygdalar area, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43858
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19769
GTEX-TKQ2-0008-SM-4DM5L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19519
DLD-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07683
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41977
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
H4K20me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Proteinuria	CTD Gene-Disease Associations	1.0	1.09998
9656_USP39_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.19194
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUPT20H_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
biological regulation	GO Biological Process Annotations 2015	1.0	null
UACC893	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65828
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Myocardial Infarction_Myocardial tissue_GSE4105	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-3.50957
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K23me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.967995
r2 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10356
respiratory system phenotype	MPO Gene-Phenotype Associations	1.0	null
GSE149264,GSE149267_4_v_3_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of facial skeleton	HPO Gene-Disease Associations	1.0	null
GTEX-OHPN-0011-R7A-SM-2I5FI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940014
Declive (VI)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.39635
KAT2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IQGAP1	Pathway Commons Protein-Protein Interactions	1.0	null
Amnion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.107
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
abnormality of the liver	HPO Gene-Disease Associations	1.0	null
respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MAMDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22068
IRF8-22096565-GC-B-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
Rhizomelic chondrodysplasia punctata	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.738
GTEX-S4Z8-0526-SM-4AD4T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950421
GTEX-S7SE-0008-SM-33HB1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38727
microbody	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.39016
H3K4me1_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-VUSG-0426-SM-3GIKD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95066
Throat	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.18
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hypotonia	MGI Mouse Phenotype Associations 2023	1.0	null
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.906914
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3578
EP300_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anteverted Nostril	DisGeNET Gene-Phenotype Associations	1.0	null
14562049-Table2	GeneSigDB Published Gene Signatures	1.0	null
PMC3607232-mmc1.xls-RS411_SEM_common_AF4_MLLN_K79Me-MLL_AF4_H3K79me3_SEM_n_2490_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6995-01A-31R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
peroxisome biogenesis disorder 11a (zellweger)	OMIM Gene-Disease Associations	1.0	null
abnormality of nervous system physiology	HPO Gene-Disease Associations	1.0	null
CAOV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11469
BRD-K23728544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40135
WM-115 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.725
GTEX-T5JC-2126-SM-32PMO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27001
KLM1	CCLE Cell Line Gene CNV Profiles	1.0	1.58095
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4146-01B-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
675_ATP6V0C_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.645344
morantel-7250	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
AC-28-RT00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.391513
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
VMRC-RCZ	GDSC Cell Line Gene Expression Profiles	-1.0	-1.71103
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.082
SMAD2	ChEA Transcription Factor Targets	1.0	null
GTEX-SN8G-0008-SM-4DM4X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47796
hypothalamic amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28641
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAPACHS77	DepMap CRISPR Gene Dependency	1.0	3.38039
BRD-K11054415	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0655
GSE182179_5_v_4_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11661
CHD2	ENCODE Transcription Factor Targets	1.0	null
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61153
BRD-K62309465	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44611
PEX14	Pathway Commons Protein-Protein Interactions	1.0	null
HS 294T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.887197
C15orf61	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24591
abnormal bone ossification	HPO Gene-Disease Associations	1.0	null
Shelterin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.072
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06602
abnormality of the skin	HPO Gene-Disease Associations	1.0	null
Nystagmus	DisGeNET Gene-Disease Associations	1.0	null
BRD-K08154407	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04329
BARHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0316
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K07550833	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.24533
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.409089
DE-30-EA70_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.25443
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K47105955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29984
RPAIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13383
Peroxisome biogenesis disorder 11A	ClinVar Gene-Phenotype Associations 2025	1.0	null
MYC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hepatoma HLE cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.69
BFTC-909	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.867937
FOSL2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	2.35091
PMC9013128-NIHMS1795992-supplement-4.xlsx-501mel_ARID2_KO_Upregulated-Gene__name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
EGR1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KAT2B	ENCODE Transcription Factor Targets	1.0	null
PMC7339546-12915_2020_793_MOESM2_ESM.xlsx-Table_S12-Table_S12_common_twin_genes_in_one_HMR_core_region_between_cattle_and_human_NR4A1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12486367-Supplementary_Data2.pdf-162-GPBP1L1_GPBP1L1	Rummagene Transcription Factor Associations 2026	1.0	null
Medial amygdalar nucleus, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20327
adenosine phosphate-5359	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
19505326-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MR-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K17410712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.55802
TE-26-XS06_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.255651
BRD-K85392247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08567
H3K79me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Trunk	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.18
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_10_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
large fontanelles	HPO Gene-Disease Associations	1.0	null
BRD-K91671568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08447
15492233-TableS1	GeneSigDB Published Gene Signatures	1.0	null
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16966
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.291008
GTEX-RVPU-0011-R1A-SM-2XCAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.15491
MYC_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QCQG-0008-SM-48U2G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860948
GSE207135_2_v_0_sod2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Uterine cervix	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.016
Pancreas	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.60884
abnormal nasal morphology	HPO Gene-Disease Associations	1.0	null
BRD-K50400833	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2385
17483311-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC6080909-JEM_20171312_TableS1.xlsx-Each_THP1_Pulldown_Expt_Targets-Unnamed_5_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of the coronary arteries	GWASdb SNP-Phenotype Associations	1.0	0.269208
NOL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30134
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07105
BRD-K83699731	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77458
Arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.571
RERFLCAD2	DepMap CRISPR Gene Dependency	1.0	4.6056
Zfx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.8264
RXRA	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4075-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nuclear outer membrane-endoplasmic reticulum membrane network	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.806
BRD-K08829593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93597
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
KAT2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r3BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25028
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TC-01A-21R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Minor Salivary Gland	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.32966
spleen	GTEx Tissue Gene Expression Profiles	-1.0	-0.886879
GTEX-U3ZH-0926-SM-4DXU4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930528
abnormal appendicular skeleton morphology	HPO Gene-Disease Associations	1.0	null
GTEX-NL4W-0011-R11A-SM-2I3DW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24637
GTEX-QV31-0126-SM-447BP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09822
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.867937
CUX1-19635798-MULTIPLE-CANCER-TYPES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
J82	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50944
periventricular stratum of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40087
Simple lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78084
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.7737
YY1_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46306
Hypertension	CTD Gene-Disease Associations	1.0	1.25619
JUN	ENCODE Transcription Factor Targets	1.0	null
SE-81-RI20_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208196
abnormality of the palm	HPO Gene-Disease Associations	1.0	null
hsa-miR-4273	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
WE-48-PP43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.200321
GTEX-T6MO-0226-SM-32QOL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949345
dobutamine-6286	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SNU387	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69575
ELF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K58324650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86879
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAP2K2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RU72-0726-SM-46MUW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8627
Peroxisome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Xanthine dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.866
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE125403_7_v_0_venetoclax_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K32782599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07294
ELF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.73846
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12891_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular response to reactive oxygen species	GO Biological Process Annotations 2025	1.0	null
Paraflocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06006
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09714
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7414-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Olanzapine	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.28
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE100528_1_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K70819166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.46646
hsa-miR-2277-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
PFSK-1	GDSC Cell Line Gene Expression Profiles	-1.0	-2.68561
PANC1005	DepMap CRISPR Gene Dependency	1.0	2.85003
LIMK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00618918
DMNB	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30539
GTEX-U4B1-0008-SM-4DXUW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2021
peroxisomal membrane	GO Cellular Component Annotations 2015	1.0	null
BRD-K05181466	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42495
BRD-K11414036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3408
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Reticulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.018
respiratory distress	MPO Gene-Phenotype Associations	1.0	null
DETROIT562	CCLE Cell Line Gene CNV Profiles	1.0	1.41284
GSE224969,GSE224971_3_v_5_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.483676
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AW-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
TRIM28_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SIU7-0001-SM-3NMAW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883084
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73B-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE157555,GSE157556_5_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SKGIIIA	DepMap CRISPR Gene Dependency	1.0	3.68255
E2F6_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gracile nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.929708
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WYVS-0326-SM-3NM9V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07962
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.881903
IGDCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10164
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.39164
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
carboxylic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
Trypanosomiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.126
H3K4me3_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HCC1599	CCLE Cell Line Gene CNV Profiles	1.0	1.88663
monocarboxylic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2822-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32042
CRCGN017_MCF10A.WT.HP_24H:A14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.081
MYB-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K40282027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19896
EGR1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GD-46-OD81_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.295369
POLR2A_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.84632
6-phosphofructokinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.876
GTEX-PWN1-0008-SM-48TEA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45411
intermediate stratum of the VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24147
12406872-Table4	GeneSigDB Published Gene Signatures	1.0	null
ETS1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K35119180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42336
4953_MED30_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.664764
BRD-K91354770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01155
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10U-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A8P1-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ventral medial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.939939
GSE101767_1_v_0_wdr11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TAF1_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-513a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
MFE280	CCLE Cell Line Gene Expression Profiles	-1.0	-2.40835
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A541-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCLAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.955
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.286026
microbody membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the endocrine system	HPO Gene-Disease Associations	1.0	null
medial preoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.32113
layer III of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12836
ELK1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Psoriatic arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.164
REST_PFSK-1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1635
Cytosol	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
496100624_PCx_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.14051
ovary	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071542
GSE131649_2_v_0_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
TBP_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the tongue	HPO Gene-Disease Associations	1.0	null
BRD-K15202679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63487
GSE65617_5_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Simple Renal Cyst	DisGeNET Gene-Disease Associations	1.0	null
Lissencephaly	DisGeNET Gene-Disease Associations	1.0	null
IGROV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
prostate_4c	HPA Tissue Sample Gene Expression Profiles	1.0	1.62664
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.456442
17880687-TableS2	GeneSigDB Published Gene Signatures	1.0	null
layer 3 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03521
Entorhinal area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00016
USF2	ENCODE Transcription Factor Targets	1.0	null
PA-TU-8902	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.867937
BRD-K70712582	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58155
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
lateral amygdaloid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03844
Memory Disorders	CTD Gene-Disease Associations	1.0	1.23743
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
r1 part of vestibulocerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06301
zona incerta	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.53578
AE-61-UO01_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.218775
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GFAP_OE_GDS1488_255_mouse_Olfactory bulb of  4 month old	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
abnormality of the retinal pigment epithelium	HPO Gene-Disease Associations	1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMARCC1	ENCODE Transcription Factor Targets	1.0	null
GTEX-XXEK-0326-SM-4BRVV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960542
Tuberous Sclerosis	DisGeNET Gene-Disease Associations	1.0	null
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.830286
Lobules IV-V, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.76797
BRD-K00933790	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04863
MBD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40666
Cataract	DisGeNET Gene-Disease Associations	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_HEPG2_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.09496
T98G	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SRF	ENCODE Transcription Factor Targets	1.0	null
GTEX-QVUS-0008-SM-447AY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17749
Erectile dysfunction	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.509691
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mental Disorders	CTD Gene-Disease Associations	1.0	1.40486
hsa-miR-2909	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
abnormal adrenocortical cell morphology	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K02392990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22583
H3K4me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CNP	Pathway Commons Protein-Protein Interactions	1.0	null
GSE158834_12_v_4_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T6MN-2626-SM-32PMQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10408
BRD-K21660570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00313
4593_LIN52_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.850462
ethosuximide-2116	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K18ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K14695590	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22113
CEBPB_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TE1	DepMap CRISPR Gene Dependency	1.0	2.57519
GSE206870,GSE206872_0_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30192
GSE162739_2_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K71716722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26409
IMPDH2	Pathway Commons Protein-Protein Interactions	1.0	null
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.32745
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15523
GSE199255,GSE199356_4_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
posterior cortical nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.976375
ETS1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNOS-0526-SM-4DM54	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00544
dorsal motor nucleus of the vagus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06489
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.57696
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.5846
Thorax	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.016
RFX5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AA-52-JS03_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.228739
GTEX-OHPN-0011-R4A-SM-2I5FD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28153
SMARCB1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.840916
GSE226285_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE175787_5_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040416
EHHADH	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K16682693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5264
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Renal Cyst	DisGeNET Gene-Phenotype Associations	1.0	null
OVCAR4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43785
K562_KW-2449_1µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0165613
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
intracellular protein transmembrane transport	GO Biological Process Annotations 2025	1.0	null
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.97619
lipid oxidation	GO Biological Process Annotations 2015	1.0	null
abnormality of carbohydrate metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.183495
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.8628
Brain - Anterior cingulate cortex (BA24)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-2.36474
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-381	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
Hemispheric regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41486
abnormal dermatoglyphics	HPO Gene-Disease Associations	1.0	null
CEBPB_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL3H-0011-R4a-SM-2I3GK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20724
hsa-miR-196a-5p	MiRTarBase microRNA Targets	1.0	null
GSE189683_1_v_2_rif1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HNF4G_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
malar flattening	HPO Gene-Disease Associations	1.0	null
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.896997
BRD-K07855097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29725
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dexpanthenol-1802	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K87404495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.15591
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857537
BRD-K01467488	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57419
LA-42-ER00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.201685
BRD-K48255349	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26752
GTEX-T5JC-1726-SM-4DM6U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07095
YY1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K38424085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11367
NY	GDSC Cell Line Gene Expression Profiles	1.0	1.58872
DYNC1H1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-N7MS-0011-R1a-SM-2HMJG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.880242
POLR2A_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1	ChEA Transcription Factor Targets	1.0	null
caudal division of IPC (area 39)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16733
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.19704
protein import into peroxisome matrix, docking	GO Biological Process Annotations 2025	1.0	null
H3K36me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GB-73-QS80_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.437242
RNF175	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17316
Cortical amygdalar area, posterior part, medial zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52986
GTEX-X5EB-1826-SM-4E3K8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37247
GTEX-S33H-0826-SM-4AD5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40956
Thyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.18
epiphyseal stippling	HPO Gene-Disease Associations	1.0	null
CRCGN011_HEPG2_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1966
cell property	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.240216
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.824264
SUPT20H	ENCODE Transcription Factor Targets	1.0	null
COV362	CCLE Cell Line Gene CNV Profiles	1.0	1.6426
ESD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41994
Very Long Chain Fatty Acid Accumulation	DisGeNET Gene-Phenotype Associations	1.0	null
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXA1_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Auditory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.243
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
IGROV-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
STAT3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_POU5F1_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
IRF8-22096565-GC-B-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN015_MCF10A_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.62945
PMC11903305-41586_2024_8507_MOESM3_ESM.xlsx-Table_S1_MAF-Hugo_Symbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
29-13 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.753
hematopoietic stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070924
OVCAR4_OVARY	CCLE Cell Line Proteomics	1.0	7.09354
Flat Occiput	DisGeNET Gene-Phenotype Associations	1.0	null
GSE196699_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K23435841	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05903
BRD-K13016489	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88352
GSE93124_0_v_1_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the testis	HPO Gene-Disease Associations	1.0	null
GSE197564,GSE198513_2_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TF1	DepMap CRISPR Gene Dependency	1.0	2.24645
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057942
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.001
SMARCC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gall bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.016
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3231
BRD-K67522096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.47202
X, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02276
Hepatomegaly	DisGeNET Gene-Phenotype Associations	1.0	null
microbody part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.78255
stratum radiatum of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.45958
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.09803
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4859-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8566112__F4	PFOCR Pathway Figure Associations 2024	1.0	null
Protein ubiquitination	Reactome Pathways 2024	1.0	null
NCIH2342	CCLE Cell Line Gene CNV Profiles	1.0	1.59773
GTEX-QVJO-0008-SM-447AU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14281
PEX19	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K20447569	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32569
Autophagosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.851
POU5F1-16153702-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE198165,GSE198166_5_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cardiomyopathy	HPO Gene-Disease Associations	1.0	null
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_2_TurboID_10m_ERM_proteome-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE131649_4_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K68540120	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.6185
Vas deferens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.956
SIN3A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE131649_4_v_0_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Dimeric IgA immunoglobulin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.909
MM370	DepMap CRISPR Gene Dependency	1.0	2.56232
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054399
CUX1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A92357389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0935
neomycin-1383	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BB-62-MS83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.388166
GTEX-OIZI-0008-SM-2XCFD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881127
abnormality of facial musculature	HPO Gene-Disease Associations	1.0	null
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
paraterete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11895
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71807
POLR3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53144
GSE142019,GSE142021_1_v_3_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
REST_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
subcallosal cingulate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.89516
abnormality of skin morphology	HPO Gene-Disease Associations	1.0	null
Severe Muscular Hypotonia	DisGeNET Gene-Phenotype Associations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-7955-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
renal cyst	HPO Gene-Disease Associations	1.0	null
BRD-K28510065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58694
PFEIFFER	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
abnormal peroxisome physiology	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-XUW1-1026-SM-4BONY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831444
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Fatty Liver	CTD Gene-Disease Associations	1.0	1.84162
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9992472-41467_2023_36735_MOESM7_ESM.xlsx-SOX11_ChIP_in_IMR-32-Unnamed_13_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
USF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pexophagosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.357
BCL3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K61259788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34121
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.891056
H3K4me3_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PFEIFFER	CCLE Cell Line Gene Expression Profiles	1.0	2.46951
H4K20me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K68953461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08022
superior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.23083
superficial stratum of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43058
PAX5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUJ4-0226-SM-4BOP8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14627
GTEX-XBEC-1326-SM-4AT69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34801
STRBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26674
GSE112763,GSE112767_0_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ARID3A	ENCODE Transcription Factor Targets	1.0	null
EDD_DEPLETION_GDS2445_116_human_embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-XUYS-0005-SM-47JZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827483
anterior amygdaloid area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.959515
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KLF4	ChEA Transcription Factor Targets	1.0	null
T3M4	BioGPS Cell Line Gene Expression Profiles	1.0	0.902664
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PACADD119	DepMap CRISPR Gene Dependency	1.0	2.47636
GTEX-OIZI-0726-SM-2XCEI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04377
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC7829553__F2	PFOCR Pathway Figure Associations 2023	1.0	null
CHERP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-5.07733
H3K14ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXM1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27654
POLR2AphosphoS5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
thin cerebral cortex	MGI Mouse Phenotype Associations 2023	1.0	null
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51584
morphological abnormality of the central nervous system	HPO Gene-Disease Associations	1.0	null
GSE234340_4_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7007-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PNGase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.775
abnormality of the intestine	HPO Gene-Disease Associations	1.0	null
Nucleus of the lateral olfactory tract, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44146
NCIH1155	CCLE Cell Line Gene Expression Profiles	-1.0	-1.9594
single-organism catabolic process	GO Biological Process Annotations 2015	1.0	null
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19395
CHO-K1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.516
bladder	GTEx Tissue Gene Expression Profiles	1.0	0.984871
GTEX-XUW1-0008-SM-4BOQH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89475
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
abnormality of the male genitalia	HPO Gene-Disease Associations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7782-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE144231_6_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PADI4-21655091-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
abnormality of the periorbital region	HPO Gene-Disease Associations	1.0	null
hippocampus (hippocampal formation)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.841803
peroxisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.3935
abnormality of the skeletal system	HPO Gene-Disease Associations	1.0	null
Peroxisomal importomer complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.636
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29D-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_4725_KO_Irx3_ERP116672	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.8225
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
KDM1A	ENCODE Transcription Factor Targets	1.0	null
GTEX-VJYA-0726-SM-4KL1T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920268
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03579
GSE225218_0_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NRF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUJ4-0008-SM-4BOQI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22591
ventrolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.967439
POU2F2_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE112763,GSE112767_0_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A73150064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35031
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
organelle part	GO Cellular Component Annotations 2015	1.0	null
BRD-K36474885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12074
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54046
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.42885
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19244
SOX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19266
Transplanted Heart Complication_Myocardial tissue_GSE582	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.54026
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.84205
CCT4	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
SMAD2-18955504-HaCaT-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
496100564_TCx_no dementia_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.29974
locomotory behavior	GO Biological Process Annotations 2015	1.0	null
GTEX-QDVJ-0008-SM-48U2E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04306
anterior cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.77472
HSDL2	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE199606_1_v_4_csf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_Meprednisone_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0122538
abnormal cerebral cortex morphology	MPO Gene-Phenotype Associations	1.0	null
USF1_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Paraflocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09214
FOXA1-25552417-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Triamcinolone_HCT15	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0142143
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.850662
abnormal renal glomerular capsule morphology	MPO Gene-Phenotype Associations	1.0	null
normoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.181488
BRCA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE160017,GSE160022_1_v_0_trem2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SRF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fetallung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.27346
thyroid_5d	HPA Tissue Sample Gene Expression Profiles	1.0	0.866835
SU-DHL-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.831412
GSE58724_1_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Catalase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.139
VZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02661
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31281
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE129725_4_v_0_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary auditory cortex (core)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.41101
BRD-K95901503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26245
ATF3	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-497	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
abnormality of the cardiac septa	HPO Gene-Disease Associations	1.0	null
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abdominal symptom	HPO Gene-Disease Associations	1.0	null
GTEX-NPJ7-0011-R4a-SM-2I3GJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18595
YY1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
interpeduncular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.11763
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_10_v_4_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GABPA_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SCABER	CCLE Cell Line Gene Expression Profiles	-1.0	-1.4537
A549	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.26867
Carcinoma	CTD Gene-Disease Associations	1.0	1.11843
GSE199255,GSE199356_4_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MBD4_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ca-Ski	GDSC Cell Line Gene Expression Profiles	1.0	1.66736
MRK-nu-1	GDSC Cell Line Gene Expression Profiles	1.0	1.4711
GTEX-S7PM-0011-R6A-SM-3NM8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5188
EXOSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09056
JAK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31169
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-1.0148
peroxisome	GO Cellular Component Annotations 2015	1.0	null
GRB2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE203158_0_v_14_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K14266419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20448
cellular response to oxygen-containing compound	GO Biological Process Annotations 2023	1.0	null
Chromosomal deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.085
BRD-K52731672	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.16977
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934153
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT5A	ENCODE Transcription Factor Targets	1.0	null
PK-45H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.030056
fatty acid alpha-oxidation	GO Biological Process Annotations 2015	1.0	null
internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063329
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8966
20460173-ImmPortCD40LandAnti-IgMvsControl	GeneSigDB Published Gene Signatures	1.0	null
GSE242290_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158834_1_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KA-75-LP02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.264677
DENND5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56111
AKT1_knockout_211_GSE39699	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.3345
CRCGN015_HEPG2_48H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.45436
Fever	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K91843292	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61346
nucleus subcoeruleus, r1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02851
Sec61 translocon complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.926
EGR1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR1E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2518
Hypospadias	DisGeNET Gene-Disease Associations	1.0	null
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Hypertrophy	DisGeNET Gene-Disease Associations	1.0	null
visual impairment	HPO Gene-Disease Associations	1.0	null
arterial stenosis	GWASdb SNP-Phenotype Associations	1.0	0.211473
H3K4me1_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CF-87-AS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.227515
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_14972_KO_Max_SRP225905	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
JHOS-4	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.32332
GSE145323,GSE145324_1_v_4_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal kidney morphology	MPO Gene-Phenotype Associations	1.0	null
TD-69-UA90_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.451878
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.386208
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03897
abnormal food intake	MPO Gene-Phenotype Associations	1.0	null
motor nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28178
Adenoma, Liver Cell	CTD Gene-Disease Associations	1.0	1.2895
Rheumatoid arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.571
DB-29-HQ45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.344778
CB-36-QH71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.374531
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Endoplasmic reticulum tubular network	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.837
PEX12	Pathway Commons Protein-Protein Interactions	1.0	null
SUZ12	ENCODE Transcription Factor Targets	1.0	null
multicystic kidney dysplasia	HPO Gene-Disease Associations	1.0	null
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1524
hsa-miR-3152-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
erythrocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.187303
H3K9ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-QMR6-0011-R1A-SM-32PKW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1261
H3K23me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60344
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A654-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
DCTN1	Pathway Commons Protein-Protein Interactions	1.0	null
SG in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.06943
BRD-K55505527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93769
Lung	GTEx Tissue Gene Expression Profiles 2023	1.0	0.911061
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JK-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
LACTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10478
GTEX-S7SE-0011-R11A-SM-2XCDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841169
posteroventral (inferior) parietal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.921168
GB-57-XV52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.206666
UCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45945
SARS-CoV MA15_Day2_None_GSE49262	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.72059
AF-01-FE42_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.305918
MAX_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ACOX1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QXCU-0326-SM-2TC63	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923753
posteroventral (inferior) parietal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.66856
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.477636
diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.305568
meiotic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.809803
abnormal locomotor activation	MPO Gene-Phenotype Associations	1.0	null
Autoimmune disease of musculoskeletal system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.571
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12563
Class I peroxisomal membrane protein import	Reactome Pathways 2024	1.0	null
lateral (dentate) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05149
Peroxisomal matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.572
Central Hypotonia	DisGeNET Gene-Phenotype Associations	1.0	null
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.4025
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7287-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA3_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
7169_RBM28_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.689466
POLR2A_K562_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K73680186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13099
BRD-K10634221	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.12653
abnormal adrenal gland morphology	MPO Gene-Phenotype Associations	1.0	null
BRD-K04087396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03575
GSE88819_6_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.828743
ctnnb1_21914722_ls174t_lof_human_gpl570_gds4386	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.288645
GSE158834_10_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-O5YT-1326-SM-3MJGR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970099
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.995081
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67035
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1155	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.854373
GSE189653,GSE203344_5_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormality of cardiac morphology	HPO Gene-Disease Associations	1.0	null
15260889-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35171
opacification of the corneal stroma	HPO Gene-Disease Associations	1.0	null
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14001
GTEX-XMK1-2026-SM-4B65K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94053
Sarcoma_SARC_TCGA-IW-A3M4-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.3793
GTEX-OIZH-2626-SM-2HMJM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00546
GSE100316_7_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-7938-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WL46-2926-SM-3LK82	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895209
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.91258
Copula pyramidis, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33837
PEX1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K17136501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19527
GSE242555_1_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
protein import into peroxisome matrix, docking	GO Biological Process Annotations 2015	1.0	null
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.77974
abnormality of the vasculature	GWASdb SNP-Phenotype Associations	1.0	0.081086
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8043-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T8EM-0226-SM-3DB7C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06847
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
raphe nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.633953
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Connective tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.571
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03212
KMBC2	CCLE Cell Line Gene Expression Profiles	1.0	2.01133
GSE211286_1_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.0552
Uterine Carcinosarcoma_UCS_TCGA-N6-A4V9-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE184356_1_v_2_tfam_human	RummaGEO Gene Perturbation Signatures	1.0	null
sparteine-4568	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NB4	DepMap CRISPR Gene Dependency	1.0	2.11325
intracellular organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
captopril_mus musculus_gpl1261_gds3683	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-R53T-0326-SM-48FEC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25514
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.679
EA-12-SS08_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201717
Death	CTD Gene-Disease Associations	1.0	1.01137
SMAD4-19686287-HACAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN011_HEPG2_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4371
GSE101112_6_v_4_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXA1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCO2	DepMap CRISPR Gene Dependency	1.0	4.67683
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYC_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
CCT2	Pathway Commons Protein-Protein Interactions	1.0	null
abnormality of metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.04685
MAX_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fatty acid catabolic process	GO Biological Process Annotations 2015	1.0	null
SOX10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5655
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8108
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.23
GTEX-NL4W-0011-R2a-SM-2I5GV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24598
Crus I, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.873372
purkinje layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.908814
RXRA_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU2F2	ENCODE Transcription Factor Targets	1.0	null
Basolateral amygdalar nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63097
Mitosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.786
abnormal renal glomerulus morphology	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19893
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.45434
MYC	ChEA Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5515-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF7L2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K94344234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14924
aplasia/hypoplasia involving the central nervous system	HPO Gene-Disease Associations	1.0	null
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.864114
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
morphological abnormality of the gastrointestinal tract	HPO Gene-Disease Associations	1.0	null
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.961025
RELA_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Thickened Nuchal Skin Fold	DisGeNET Gene-Phenotype Associations	1.0	null
BB30-HNC	GDSC Cell Line Gene Expression Profiles	1.0	2.16081
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.04469
Optic Atrophy	DisGeNET Gene-Disease Associations	1.0	null
RFX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4UY-0926-SM-4AD6O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869197
abnormality of the nasal alae	HPO Gene-Disease Associations	1.0	null
BRD-K79631534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07363
BRD-K67979704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25289
Retinitis pigmentosa 28	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.625
CUX1	ChEA Transcription Factor Targets	1.0	null
single transverse palmar crease	HPO Gene-Disease Associations	1.0	null
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975917
Lung adenocarcinoma_LUAD_TCGA-J2-8194-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1359	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0001
IGR-37	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.76171
abnormality of long bone morphology	HPO Gene-Disease Associations	1.0	null
TBP_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nervous System Diseases	CTD Gene-Disease Associations	1.0	1.06952
E2F4-17652178-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
EP300_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41776
GSE226249_2_v_4_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8672
SYK_knockdown_279_GDS3609	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.94974
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PQ-2626-SM-33HC9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01615
AF-00-QK19_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.249253
COV434	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.23661
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_4_Overlap_of_ERM_proteom-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
TUHR14TKB	DepMap CRISPR Gene Dependency	1.0	2.11344
NR2F2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.338884
TUBG2	Pathway Commons Protein-Protein Interactions	1.0	null
chemostat culture	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.00458
bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.591224
GSE178532_1_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Mesothelioma_MESO_TCGA-LK-A4NW-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193993_0_v_7_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
alvespimycin-1213	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE142210_2_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1861
TUBB8	Pathway Commons Protein-Protein Interactions	1.0	null
Cortical subplate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04122
specifically	GeneRIF Biological Term Annotations	1.0	null
liver_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.00287
GSE157594_6_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE157594_6_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Peroxisomal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.177
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YQ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intracellular trafficking and peroxisomes	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.00621
abnormal eye morphology	HPO Gene-Disease Associations	1.0	null
TEAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33766
Congenital symmetric circumferential skin creases 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.301
E2F4_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endoplasmic reticulum part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.061592
amygdaloid complex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.849233
cataract	HPO Gene-Disease Associations	1.0	null
GTEX-TSE9-0011-R1A-SM-3DB7E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.991334
CRCGN013_HEPG2_24H:B07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.21744
Lung adenocarcinoma_LUAD_TCGA-78-7145-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43367
BRD-K36176998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3969
GSE179531_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-503	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
ventrolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.04535
GTEX-WK11-2726-SM-3NMAQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880585
Stippled Epiphyses	DisGeNET Gene-Phenotype Associations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q6-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-548aj	TargetScan Predicted Conserved microRNA Targets	1.0	0.017945
t64-ovaries_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.86596
cho cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.625061
hsa-miR-509-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
DMS454	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68199
abnormal locomotor behavior	MPO Gene-Phenotype Associations	1.0	null
cuneate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06618
SIN3A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
medial geniculate complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.892342
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.6473
GTEX-U3ZN-0326-SM-3DB86	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920003
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A57E-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX4	MotifMap Predicted Transcription Factor Targets	1.0	null
S0-EE-Y737_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214291
PMC7730811-13148_2020_983_MOESM1_ESM.xlsx-Table_S3C_HNF4A_Target_Genes-Table_S3C_HNF4A_Target_Genes_Average_Colon_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
nicergoline-6251	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
osteoblasts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.22959
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44284
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.32047
Uvula (IX), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31653
Parathyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.216
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K22974051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74871
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.880004
SARS-CoV MA15_Day1-PFU-10^3_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.05588
GTEX-UJMC-0326-SM-3GAE2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63638
VZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1884
liver	HPA Tissue Gene Expression Profiles	1.0	0.912028
Cervix - Endocervix	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.28114
granular layer of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.842339
PMC10290283-biol-2022-0622-sm3.pdf-402-FOXB1_FOXB1	Rummagene Transcription Factor Associations 2026	1.0	null
OD-96-OP94_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215986
Gracilis muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.574
SD-69-QA40_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.240319
layer 1 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.94813
BRD-K86155400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49424
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5832-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skeletal Dysplasia	DisGeNET Gene-Disease Associations	1.0	null
A549_Vandetanib_1µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0147334
GSE196343_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158834_2_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
b220.bcell	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.00074
T-REx 293 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.631
BRD-K93335719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60322
male reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071676
GSE192860_0_v_1_trifluoperazine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PAX6	ChEA Transcription Factor Targets	1.0	null
TCF12_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR2C2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pyloric Stenosis	DisGeNET Gene-Phenotype Associations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-92-7340-01A-21R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Posterolateral visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22247
FOXA1-27197147-CHIP-SEQ-ENDOMETRIOID-ADENOCARCINOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-NPJ8-1926-SM-3MJGB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28076
abnormal gland morphology	MPO Gene-Phenotype Associations	1.0	null
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.913239
TE-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Protein localization	Reactome Pathways 2024	1.0	null
medial tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16916
Kidney renal papillary cell carcinoma_KIRP_TCGA-KV-A74V-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.87696
Brain Lower Grade Glioma_LGG_TCGA-S9-A89Z-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.289
hsa-miR-4779	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
H3K27ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HDAC2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:M21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0163
abnormal nephron morphology	MPO Gene-Phenotype Associations	1.0	null
H3K9ac_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K03935681	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27835
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE186660_2_v_1_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Elevated Hepatic Transaminase	DisGeNET Gene-Phenotype Associations	1.0	null
GSE193402_0_v_2_imatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE205729,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
REH	DepMap CRISPR Gene Dependency	1.0	2.11862
Low-Set, Posteriorly Rotated Ears	DisGeNET Gene-Phenotype Associations	1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.305
abnormality of the palmar creases	HPO Gene-Disease Associations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A5XZ-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EP300_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of LAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.34343
CEBPD_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal mitochondrial crista morphology	MPO Gene-Phenotype Associations	1.0	null
CBX3	ENCODE Transcription Factor Targets	1.0	null
Perturb_5225_KO_Mettl3_SRP184527	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
BRCA1	ENCODE Transcription Factor Targets	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-S4-A8RM-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GPANK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24402
SNRPD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44964
HEL9217	DepMap CRISPR Gene Dependency	1.0	3.78197
G120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.867937
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CCNT2	ENCODE Transcription Factor Targets	1.0	null
abnormality of the myocardium	HPO Gene-Disease Associations	1.0	null
BRD-K05704547	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63483
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.846841
GSE168076,GSE168080_1_v_0_batf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.53615
GTEX-VJYA-0426-SM-3GIJK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904178
USF2_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-0011-R9A-SM-2TF67	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39157
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14869
ETS1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
19723343-SuppFigure4	GeneSigDB Published Gene Signatures	1.0	null
FOXP2	ENCODE Transcription Factor Targets	1.0	null
Glycosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.352
CTCF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4876-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
III, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13234
PRXL2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01583
MYB-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RTLS-1126-SM-46MUQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882315
SU-DHL-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.29085
CRCGN016_MCF10A.TP53.M_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.51149
H3K4me1_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE214596,GSE214598_1_v_2_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Inflammation	CTD Gene-Disease Associations	1.0	1.60944
Large Fontanelle	DisGeNET Gene-Phenotype Associations	1.0	null
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Posterior Embryotoxon	DisGeNET Gene-Disease Associations	1.0	null
Lobule III, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.97397
GTEX-TMMY-0008-SM-4DXU3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916803
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0274
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7606-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QMR6-0011-R7A-SM-32PKL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.982364
global developmental delay	HPO Gene-Disease Associations	1.0	null
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.82217
GTEX-N7MT-0326-SM-48TDP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838695
Edema	CTD Gene-Disease Associations	1.0	1.46909
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836165
BRD-K20426211	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28597
Weight Loss	CTD Gene-Disease Associations	1.0	1.66124
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30093
hsa-miR-607	TargetScan Predicted Conserved microRNA Targets	1.0	0.050854
GSE198982,GSE198986_1_v_2_daunorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PC-44-DH10_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.254006
primary visual cortex (striate cortex, area V1/17)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.844168
Lobule II, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66042
hsa-miR-4524	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
SRF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5950532__F6	PFOCR Pathway Figure Associations 2023	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3444-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Malpighian tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.77
BRD-K92365616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26482
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Outer mitochondrial membrane protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.146
496100571_FWM_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.24417
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935991
STAT1	ENCODE Transcription Factor Targets	1.0	null
GSE149124,GSE149128_2_v_1_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.9565
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
diprophylline-1811	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Generalized Hypotonia	DisGeNET Gene-Phenotype Associations	1.0	null
RUNX1-17652178-JURKAT-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR2F2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TYSND1	Pathway Commons Protein-Protein Interactions	1.0	null
FOS	ENCODE Transcription Factor Targets	1.0	null
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3J8-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-K1-A42X-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.39715
PMC6638267__F8	PFOCR Pathway Figure Associations 2024	1.0	null
BRD-K69668687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2908
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8332-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.373
anterior (rostral) cingulate (medial prefrontal) cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.72024
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.050837
zbtb7b_19734230_cd8_p14_memory_lof_mouse_gpl1261_gds3566	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.932368
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.29103
abnormal cerebrum morphology	MPO Gene-Phenotype Associations	1.0	null
CDK5_knockdown_99_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.00286
POLR2A_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K01095342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8237
H3K4me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NRN1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66505
H3K27ac_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-X5EB-1726-SM-4E3J7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9598
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Piriform-amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81781
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6609
upslanted palpebral fissure	HPO Gene-Disease Associations	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
praziquantel-5874	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.20589
abnormality of the fontanelles or cranial sutures	HPO Gene-Disease Associations	1.0	null
GSE140607_1_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-4799-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.004732
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.199
DNA topoisomerase IV complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.703
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
MOGGUVW	DepMap CRISPR Gene Dependency	1.0	3.28206
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53662
POU5F1-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
facial motor nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.64778
hsa-miR-3622a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
DG-75	GDSC Cell Line Gene Expression Profiles	-1.0	-1.42209
short stature	HPO Gene-Disease Associations	1.0	null
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.81222
bradykinesia	MGI Mouse Phenotype Associations 2023	1.0	null
CREM	ChEA Transcription Factor Targets	1.0	null
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CSNK1G3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04587
BRD-K82793574	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22925
MYC_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
aplasia/hypoplasia of the cerebrum	HPO Gene-Disease Associations	1.0	null
GSE125014_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.937344
POLR2AphosphoS5_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE114883_0_v_5_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SMARCB1	ENCODE Transcription Factor Targets	1.0	null
abnormality of coagulation	HPO Gene-Disease Associations	1.0	null
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.30368
GTEX-NL3H-0011-R1a-SM-48TDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67296
abnormality of the cornea	HPO Gene-Disease Associations	1.0	null
III	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.857919
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
rough endoplasmic reticulum membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.194698
NXT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36633
YY1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K01717817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43325
hsa-miR-548e	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08632
ARID3A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCFC1_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4797-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.119151
BRD-K52259096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89963
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.969986
CCT8	Pathway Commons Protein-Protein Interactions	1.0	null
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.927509
SIX5	ENCODE Transcription Factor Targets	1.0	null
NCIH1623	CCLE Cell Line Gene CNV Profiles	1.0	1.59854
XRN2	ChEA Transcription Factor Targets	1.0	null
PML_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Refsum disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.058
BRD-K60295429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08706
abnormality of the pylorus	HPO Gene-Disease Associations	1.0	null
gonad	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.272649
GABPA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A263-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inherited metabolic disorder	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
hsa-miR-4724-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.008128
TAL1-21186366-BM-HSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38599
Declive (VI), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.33437
CHD7	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-483-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
PMC11342215-mmc2.xlsx-Protein_list-Table_S1_Protein_information_of_LC-MS_MS_data_from_one_analysis_between_FXN_KD_and_Ctrl_of_Ovcar5_spheroids_related_to_Figure_4_and_STAR_methods_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SCH	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.12273
generation of neurons	GO Biological Process Annotations 2025	1.0	null
GSE163862_2_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
subgranular zone of caudal dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.938951
BRD-A47963183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21724
BRD-K23434564	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62536
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
peroxisomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.34665
EP300_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01861
GSE142019,GSE142021_10_v_3_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Glycosome lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.521
AF4-26711339-SEM-HUMAN-BLOOD-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
Foxn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.7765
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835532
GTEX-XOTO-0011-R6B-SM-4B65X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15918
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
dorsolateral part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20879
Learning Disorders	CTD Gene-Disease Associations	1.0	1.31686
GTEX-QEG5-1126-SM-33HC2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915681
H3K4me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DA-58-LZ09_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.258552
CRCGN015_HEPG2_48H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19956
import	GeneRIF Biological Term Annotations	1.0	null
BRD-K05119275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40683
GSE203158_12_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TAF1_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Spleen	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.34436
all	HPO Gene-Disease Associations	1.0	null
GSE163920_1_v_0_sirt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-8127-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Atrophy	CTD Gene-Disease Associations	1.0	1.03197
Fetal Death	CTD Gene-Disease Associations	1.0	1.63227
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-WHSE-0011-R3A-SM-3P5ZM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.897432
Piriform-amygdalar area, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.94813
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.168854
CREB1	ChEA Transcription Factor Targets	1.0	null
rnf2_20805357_u2os_osteosarcoma_lof_human_gpl570_gse23035	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.125811
DHRS4	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.936274
RCOR1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
low-set, posteriorly rotated ears	HPO Gene-Disease Associations	1.0	null
hsa-miR-26b	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
BRD-K21671578	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98239
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DCAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90521
PPARA-22158963-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K11812419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33604
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-548p	TargetScan Predicted Conserved microRNA Targets	1.0	0.212286
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
solitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.959182
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.69007
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE162739_7_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_retinal pigment epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO741	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46016
Endoplasmic reticulum membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.806
neuron migration	GO Biological Process Annotations 2015	1.0	null
CE-95-YX02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.616488
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40542
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
dorsolateral part of Lat	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2902
Purkinje cell layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46977
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.867937
H3K14ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC7730811-13148_2020_983_MOESM1_ESM.xlsx-Table_S3D_HNF1A_Target_Genes-Table_S3D_HNF1A_Target_Genes_Average_Colon_HNF1A	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K36me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Parasitic protozoa infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.07
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K28093873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01615
BRD-K41063113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30091
POLR2A_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFIC_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EGR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Azacitidine_10µM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0104273
BRD-K59680547	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.16475
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.32315
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.2921
GTEX-XLM4-0011-R9A-SM-4AT45	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0749
BRD-K06926365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16962
CD-13-QZ32_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.309067
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
viscus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.35875
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.78208
CEBPZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SE-0011-R7A-SM-2XCDI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02426
Spasticity, Ctcae	DisGeNET Gene-Phenotype Associations	1.0	null
MYBL2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
smooth muscle	HPA Tissue Protein Expression Profiles	-1.0	-1.49554
protein import into peroxisome matrix, docking	GO Biological Process Annotations 2023	1.0	null
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	1.0	3.11052
RKO	DepMap CRISPR Gene Dependency	1.0	2.5762
USF2	JASPAR Predicted Transcription Factor Targets	1.0	null
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.13552
cellular response to oxidative stress	GO Biological Process Annotations 2025	1.0	null
VA-92-QP54_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.23981
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
icSARS CoV_60Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.64634
Inflammatory bowel disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.012
SKMEL2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.89153
BRD-K10704442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42957
UBTF	ENCODE Transcription Factor Targets	1.0	null
SIN3A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.60568
GTEX-REY6-0526-SM-2TF5M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01603
infantile refsum disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.58136
GSE202434,GSE202438_13_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TAF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K45936761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10235
Omeprazole (sodium)_A-427	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.013776
PMC7746852__F3	PFOCR Pathway Figure Associations 2024	1.0	null
NUGC3	CCLE Cell Line Gene CNV Profiles	1.0	1.33525
HCC1171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.92086
QB-69-QH67_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.246064
GSE127790_4_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intracellular organelle	LOCATE Curated Protein Localization Annotations	1.0	null
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.31684
protein import into peroxisome matrix	GO Biological Process Annotations 2023	1.0	null
upper motor neuron dysfunction	HPO Gene-Disease Associations	1.0	null
PMC11908325-media-2.xlsx-Table10_MR-Unnamed_6_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.60808
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.73898
SPI1-22790984-ERYTHROLEUKEMIA-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PBX3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
trachea	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
POLR2A_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal cell physiology	MPO Gene-Phenotype Associations	1.0	null
GSE149903_4_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
arl6	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.646
peroxisomes	GeneRIF Biological Term Annotations	1.0	null
Adrenocortical carcinoma_ACC_TCGA-PK-A5HB-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE171292_1_v_0_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
12598313-Table4	GeneSigDB Published Gene Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84I-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Fetal Growth Retardation	CTD Gene-Disease Associations	1.0	1.08055
SP1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PML_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.857876
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89977
BRD-K51270604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06934
c1595a	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.402
disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
CREB1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TET1	ChEA Transcription Factor Targets	1.0	null
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K32402344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6274
GTEX-PSDG-1326-SM-48TD2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918861
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P7-A5NX-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Hypertrophy	CTD Gene-Disease Associations	1.0	1.95087
single-organism localization	GO Biological Process Annotations 2015	1.0	null
4954_MED31_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.546795
suckling behavior	GO Biological Process Annotations 2015	1.0	null
CRB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15995
ZEB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.897492
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.974866
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A13J-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_9548_KO_Ucp1_SRP323371	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.06994
medial superior olive	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16153
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.20085
cisplatin_homo sapiens_gpl570_gse23553	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FGFR2_activemutant_59_GSE17916	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.56877
cerebral degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.06438
septum (resp epith)	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.1732
hippocampus (hippocampal formation)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.874316
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K71881549	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83487
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DD-30-SX80_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.320466
ZNF684	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38897
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QDT8-0006-SM-32PL3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07164
intermediate stratum of LAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79194
parathyroid gland	HPA Tissue Protein Expression Profiles	1.0	1.02714
membrane region	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.069772
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYC-20876797-MEDULLOBLASTOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
USF2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cauline leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.565
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table4_gnomAD_EAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4224-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central gray of the pons, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.950182
19399471-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
Parasitic infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.009
CRCGN015_HEPG2_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.06677
abnormal adrenocortical cell morphology	MPO Gene-Phenotype Associations	1.0	null
KIF11	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OHPL-2426-SM-48TDN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03711
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27596
ventral part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30166
Zellweger Spectrum	DisGeNET Gene-Disease Associations	1.0	null
MDA-MB-231	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23727
hsa-miR-4714-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
microbody part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K15675930	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31565
JUND_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
testis_7d	HPA Tissue Sample Gene Expression Profiles	1.0	1.06344
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
BRD-K77801455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57685
SUM1315MO2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.84627
telencephalon cell migration	GO Biological Process Annotations 2025	1.0	null
Gustatory areas, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22625
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.888055
BRD-K75576005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01471
CREB1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Declive (VI), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.46835
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.67384
T47D	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4099
GTEX-XQ3S-0008-SM-4GIDZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858004
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.54999
Cortical amygdalar area, posterior part, lateral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22873
TCF12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease of metabolism	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ASH2L	ChEA Transcription Factor Targets	1.0	null
hepatic failure	HPO Gene-Disease Associations	1.0	null
ghost	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.486326
MPP89	CCLE Cell Line Gene CNV Profiles	1.0	1.89093
premature birth	HPO Gene-Disease Associations	1.0	null
Smooth endoplasmic reticulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.156
BRD-K17285234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27588
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.22195
organic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
BE-27-RQ61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.426123
NALM6	DepMap CRISPR Gene Dependency	1.0	3.48277
disease	GWASdb SNP-Disease Associations	1.0	0.02704
medial amygdala, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22437
Culmen	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77325
HCC1195	CCLE Cell Line Gene Expression Profiles	1.0	2.08338
Microcephaly	DisGeNET Gene-Disease Associations	1.0	null
POLR2AphosphoS5_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vitamin c_homo sapiens_gpl570_gse11919	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
endoplasmic reticulum membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.117793
RBMY1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33096
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895674
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30266
stat3_18500982_mesc_gof_mouse_gpl83_gds3446	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.775013
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21239
BRD-K63364685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2228
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.55286
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.957479
GTEX-NL3H-0011-R7a-SM-2I3G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.992138
BRD-K60734771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03794
ELF1_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRAT	Pathway Commons Protein-Protein Interactions	1.0	null
Smooth endoplasmic reticulum membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.266
CD19+_BCells(neg._sel.)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.38888
USF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE178292_0_v_3_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE136742,GSE136744_0_v_3_setd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormality of the retina	HPO Gene-Disease Associations	1.0	null
TAF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Weight Gain	CTD Gene-Disease Associations	1.0	1.3314
DOK	GDSC Cell Line Gene Expression Profiles	1.0	1.80608
PTEN_KD_GDS2958_100_human_HCC827 - NON-SMALL CELL LUNG carcinoma cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K82187446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35654
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54E-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Timothy Syndrome	DisGeNET Gene-Disease Associations	1.0	null
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.389296
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55142
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.15797
abnormality of central nervous system electrophysiology	HPO Gene-Disease Associations	1.0	null
E2F4	ChEA Transcription Factor Targets	1.0	null
subpallial amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3543
CEBPB_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of central motor function	HPO Gene-Disease Associations	1.0	null
GSE151612_4_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
POU5F1-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Type 1 diabetes mellitus_pancreatic islet_GSE2254	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.36808
HT-1197	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KYSE-510	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.66685
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MYOD1_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8985
microbody membrane	GO Cellular Component Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-5131-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73119
EEF1AKMT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02511
PEX2	Pathway Commons Protein-Protein Interactions	1.0	null
embryonic fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.255567
GSE135334,GSE136010_2_v_3_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47494
CTCF_epithelial cell of proximal tubule_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8XH-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perinuclear region of cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.766
hTERT-RPE1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.673
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40893
r2 part of nucleus subcoeruleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29076
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE103122_0_v_1_puromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.839783
NFIC_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6524
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ASH2L-23239880-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
SIG-M5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00929
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12218
GTEX-N7MS-0011-R7a-SM-2HMKN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.974721
GTEX-PWO3-0011-R1A-SM-2I5EW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.89104
BRD-K58844095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46311
JHOC5	DepMap CRISPR Gene Dependency	1.0	3.71992
BRD-K95648552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52302
GTEX-SJXC-0726-SM-2XCFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33516
fatty acid alpha-oxidation	GO Biological Process Annotations 2023	1.0	null
Pharyngeal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.913
MXI1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC3371315-NIHMS350140-supplement-8.xls-MCF7-T47D-SK-453_Down_MCF7-T47D-Supplementary_Table_1_ER-positive_FOXA1_signature_Genes_decreased_only_in_MCF7_and_T47D_cells_with_knockdown_of_FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
metabolic process	GO Biological Process Annotations 2015	1.0	null
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial parabrachial nucleus,right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10024
pi1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.755
membrane	GO Cellular Component Annotations 2015	1.0	null
acebutolol-1911	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
leukodystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.19229
GSE113734_3_v_0_qprt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K69901388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75107
BRD-K74500173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24762
GSE185519_6_v_5_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXP3-21729870-TREG-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0486
Sarcoma_SARC_TCGA-DX-A48R-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Purkinje layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.992
GSE214823,GSE214824_0_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
glycosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.44855
integral component of organelle membrane	GO Cellular Component Annotations 2015	1.0	null
Basolateral amygdalar nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.06385
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.59347
Rectum adenocarcinoma_READ_TCGA-DC-6154-01A-31R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE258991_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT5A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K51322795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23129
hsa-miR-3925-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
USF1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSTK1	Pathway Commons Protein-Protein Interactions	1.0	null
LAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18582
abnormality of the mandible	HPO Gene-Disease Associations	1.0	null
MCF7_Maraviroc_1µM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0186171
aplasia/hypoplasia of the mandible	HPO Gene-Disease Associations	1.0	null
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.399114
GTEX-V955-1926-SM-4KL1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21854
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36785
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065211
Global Developmental Delay	DisGeNET Gene-Disease Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6935-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRF_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anterior hypothalamic nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0584
hypertrophic cardiomyopathy	HPO Gene-Disease Associations	1.0	null
BRD-A41199690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03357
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
hsa-miR-548l	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.72111
CEBPB_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03814
GTEX-RVPU-0011-R7A-SM-2XCAB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.32819
CREB1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the respiratory system	HPO Gene-Disease Associations	1.0	null
2858_FAM136A_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.573208
Primary somatosensory area, trunk, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14839
hsa-miR-1305	TargetScan Predicted Conserved microRNA Targets	1.0	0.115091
abnormality of body weight	HPO Gene-Disease Associations	1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.73675
BRD-K62147342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21723
Micrognathism	DisGeNET Gene-Disease Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5702-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
facial palsy	HPO Gene-Disease Associations	1.0	null
6581_POT1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.522048
Gustatory areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02921
Luteal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.559
septal organ	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.824547
perinatal lethality	MPO Gene-Phenotype Associations	1.0	null
BRD-K30117087	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43681
Septin ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.671
Short Stature, Ctcae	DisGeNET Gene-Phenotype Associations	1.0	null
GSE223908,GSE223909_1_v_6_serpinb3_human	RummaGEO Gene Perturbation Signatures	1.0	null
ACTG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3653
NCIH2087	DepMap CRISPR Gene Dependency	1.0	2.54488
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM18526_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.25882
GSE198165,GSE198166_6_v_11_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QMR6-0008-SM-447AV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19456
abnormality of the female genitalia	HPO Gene-Disease Associations	1.0	null
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X5EB-0726-SM-46MVR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00852
peroxisomal	GeneRIF Biological Term Annotations	1.0	null
CRCGN016_MCF10A.TP53.M_24H:G17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.17247
localization	GO Biological Process Annotations 2015	1.0	null
hsa-miR-300	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
polymicrogyria	HPO Gene-Disease Associations	1.0	null
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.848169
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043173
abnormal stationary movement	MPO Gene-Phenotype Associations	1.0	null
BRD-K77892726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65458
BRD-K92349794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05762
Breast Cancer_Mammary Gland Tissue_GSE1872	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.64543
GSE48812_9_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
CREB1	ENCODE Transcription Factor Targets	1.0	null
TCF3-18347094-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K00698280	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27477
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organelle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.624781
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Wide Anterior Fontanel	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K64449549	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98632
HEPG2	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.93348
anterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02095
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19244
abnormal liver morphology	MPO Gene-Phenotype Associations	1.0	null
496100604_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.34605
Failure To Thrive	DisGeNET Gene-Disease Associations	1.0	null
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K04695511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61454
CITED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15271
JUN_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K55465787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49218
CEBPZ	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5985-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBC1D15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52284
ventral part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05276
GSE104508_2_v_3_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cerebellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.109554
HCCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32675
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.1265
H4K5ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HCC1937	DepMap CRISPR Gene Dependency	1.0	3.29048
GABPA_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Omeprazole (sodium)_COLO 205	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00745021
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.893388
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K62018188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8926
E2F6	ENCODE Transcription Factor Targets	1.0	null
K562	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52916
CRCGN016_MCF10A.TP53.M_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01905
SRF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK4_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F4-17652178-JURKAT-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-VJWN-0726-SM-3GIJ8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76396
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6032-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-PLZ6-0008-SM-48TD5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60128
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.526
RAD21	ENCODE Transcription Factor Targets	1.0	null
POLR2AphosphoS5_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
KMS-21BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.14306
Bounding membrane of organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.624
KIFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07668
1040_C1ORF131_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.07585
A549_2-Methoxyestradiol_1µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0128529
BRD-K56879482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49728
BRD-K02299361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15488
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.61106
BRD-K26836050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4076
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40427
NCIH1792	CCLE Cell Line Gene CNV Profiles	1.0	2.59998
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GRB2	Hub Proteins Protein-Protein Interactions	1.0	null
Abnormalities, Multiple	CTD Gene-Disease Associations	1.0	1.1403
GTEX-Q2AG-0011-R8A-SM-2HMK5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.999175
GSE158834_12_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-4591-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hyperreflexia	HPO Gene-Disease Associations	1.0	null
HCC2935	CCLE Cell Line Gene Expression Profiles	1.0	1.54218
prostate_4b	HPA Tissue Sample Gene Expression Profiles	1.0	0.871402
hsa-miR-4418	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
BRD-K35296094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25634
GSE190316,GSE190324_10_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DNAJA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13773
amygdalo-striatal transition	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.83559
aphagia	MPO Gene-Phenotype Associations	1.0	null
hsa-miR-4262	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
CRCGN009_HEPG2_24H:F20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6265
496100579_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.92484
H3K56ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
incoordination	HPO Gene-Disease Associations	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
SMAD2-18955504-HACAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5KX-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TSE9-0011-R8A-SM-3DB7R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05387
HDAC2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF7L2_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5989-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.9141
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH2110	CCLE Cell Line Gene Expression Profiles	1.0	1.55565
BRD-K16468319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75312
SIN3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.15775
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SMARCD1-25818293-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Simple lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64496
PANC0813	DepMap CRISPR Gene Dependency	1.0	2.80262
SARS-CoV MA15_Day7-C57BL6_None_GSE51386	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.51485
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4799-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K79me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
LATS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15547
POLR2A_K562_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
isoxsuprine-1904	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
abnormal involuntary eye movements	HPO Gene-Disease Associations	1.0	null
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.012
SNU719	CCLE Cell Line Gene CNV Profiles	1.0	1.34157
terazosin-2530	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
posterolateral cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.13509
BRD-K73582217	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06575
ECH1	Pathway Commons Protein-Protein Interactions	1.0	null
H2BK12ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ARHGEF2	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-548ae	TargetScan Predicted Conserved microRNA Targets	1.0	0.017945
SRF_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTA3	ENCODE Transcription Factor Targets	1.0	null
pirinixic acid-487	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TEAD4_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
monolayer-surrounded lipid storage body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.767
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FAR1	Pathway Commons Protein-Protein Interactions	1.0	null
neonatal lethality	MPO Gene-Phenotype Associations	1.0	null
HCC1954	CCLE Cell Line Gene Expression Profiles	1.0	1.5304
Lipid metabolism disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.034
basolateral amygdaloid nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69713
BRD-K06313694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08491
Entorhinal area, medial part, ventral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35183
Golgi trans cisterna	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.962
ETS1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane-enclosed lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.621804
IKZF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-O5YT-0226-SM-32PK5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899156
GTEX-PVOW-0008-SM-48TE8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847219
abnormality of epiphysis morphology	HPO Gene-Disease Associations	1.0	null
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.20916
BRD-K95035301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52005
thyroid gland	HPA Tissue Protein Expression Profiles	1.0	1.02714
hsa-miR-4263	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
tardbp_19910924_hek293e_lof_human_gpl570_gds3730	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.505936
Cns Hypomyelination	DisGeNET Gene-Phenotype Associations	1.0	null
GSE88819_6_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-181a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Pyramus (VIII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83031
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.849297
RELA_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dyslipidemias	CTD Gene-Disease Associations	1.0	1.05015
seizures	HPO Gene-Disease Associations	1.0	null
BRD-K58696904	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15586
BRD-K27671601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32017
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.94738
Brain Lower Grade Glioma_LGG_TCGA-HT-A617-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
determining	GeneRIF Biological Term Annotations	1.0	null
UCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43189
GTEX-RVPU-0011-R5A-SM-2XCAD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839167
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.50565
PMC10837142__F7	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.48158
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
pts1	GeneRIF Biological Term Annotations	1.0	null
r1 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31684
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POU5F1-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.48048
IRF4_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
microtubule-based process	GO Biological Process Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EU-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.5562
USF1_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
carbohydrate metabolism disease	GWASdb SNP-Disease Associations	1.0	0.262771
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.2617
HIPK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28637
posterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14435
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MY-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Infantile Muscular Hypotonia	DisGeNET Gene-Phenotype Associations	1.0	null
H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-Q2-A5QZ-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
JUND_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A194-01A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE82032_3_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.3447
REST_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GRPEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09871
FOSL2	ENCODE Transcription Factor Targets	1.0	null
MEF2A	ENCODE Transcription Factor Targets	1.0	null
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.97443
GSE140651,GSE140653_2_v_1_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-N7MS-0011-R11A-SM-2HMJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09692
H3K4me1_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
abnormal enchondral ossification	HPO Gene-Disease Associations	1.0	null
IA-27-CK10_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.218432
OVMANA	CCLE Cell Line Gene Expression Profiles	1.0	2.01439
H3K79me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
QA-50-YO37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.315294
Copula pyramidis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28392
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
outer CP in (rostral) midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.4363
cellular process	GO Biological Process Annotations 2015	1.0	null
4540_LDB1_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.785093
testis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.297447
MYBL2	ChEA Transcription Factor Targets	1.0	null
CRCGN015_MCF10A.TP53.M_24H:A22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0217
carboxylic acid catabolic process	GO Biological Process Annotations 2015	1.0	null
patient	GeneRIF Biological Term Annotations	1.0	null
GSE158834_12_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH322	CCLE Cell Line Gene Expression Profiles	1.0	1.5776
GTEX-N7MS-0011-R4a-SM-2HMKW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.834741
GSE161295_4_v_1_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6VC-01A-23R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Underdeveloped Supraorbital Ridges	DisGeNET Gene-Phenotype Associations	1.0	null
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZH-0002-SM-3NMDD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865753
RUNX3	ENCODE Transcription Factor Targets	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
PEX7	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-Q2AG-1026-SM-33HBW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916107
BRD-K32418104	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24984
CUX1-19635798-MULTIPLE HUMAN CANCER CELL TYPES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
cell culture	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.095679
microcephaly	HPO Gene-Disease Associations	1.0	null
SIX5_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03087
PECR	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5876-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX2-16153702-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K82460510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5269
Hepatic Cirrhosis_Hepatic Tissue_GSE1843	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.25328
EmrE multidrug transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.602
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.99991
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00403
bed nucleus of stria terminalis, lateral amygdaloid division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40087
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Congenital Epicanthus	DisGeNET Gene-Disease Associations	1.0	null
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PMC4777381-pone.0150624.s006.xlsx-dif_exp_AD-ZBTB38_ZBTB38	Rummagene Transcription Factor Associations 2026	1.0	null
GSE174701_5_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K01995700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71773
GSE174701_5_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Microcephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.295
CRCGN015_MCF10A.TP53.M_24H:F22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.089
uterine cervix	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.117815
TMEM248	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73971
Brain Lower Grade Glioma_LGG_TCGA-P5-A72W-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH2342	CCLE Cell Line Gene Expression Profiles	1.0	1.94534
hsa-miR-4684-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
KCIMOH1	DepMap CRISPR Gene Dependency	1.0	2.95177
GSE210655_1_v_7_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K68305833	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51073
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.44817
BRD-A57594599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18824
GSE142588_2_v_0_cinobufagin_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.4678
YY1-33199912-293T-HUMAN-KIDNEYEMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
Hmgn1_KO_GDS5010_406_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NCIH146	CCLE Cell Line Gene Expression Profiles	-1.0	-2.364
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17131
Acatalasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.54
hypoglossal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02477
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10X-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE136869_1_v_0_lpar2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Premature Birth	DisGeNET Gene-Phenotype Associations	1.0	null
SRF	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE210225_0_v_1_uba6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.868363
IRF8	ChEA Transcription Factor Targets	1.0	null
GSE149123,GSE149128_2_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary auditory cortex (core)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.37424
abnormal cerebral cortex morphology	MGI Mouse Phenotype Associations 2023	1.0	null
SRF_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A3F2-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Cortical amygdalar area, posterior part, medial zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56834
BRD-K63410075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20855
HEC-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.12014
POLR2A_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SF539	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42144
Elevated Levels Of Phytanic Acid	DisGeNET Gene-Phenotype Associations	1.0	null
STAT5A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4539	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table5_gnomAD_SAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K16705729	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17767
GNPAT	Pathway Commons Protein-Protein Interactions	1.0	null
Rectum adenocarcinoma_READ_TCGA-BM-6198-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE145323,GSE145324_1_v_0_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Seminal vesicle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.016
E2F4	ENCODE Transcription Factor Targets	1.0	null
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19244
GSE230174_0_v_1_glycerol_human	RummaGEO Drug Perturbation Signatures	1.0	null
TRIM47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59711
Prostate adenocarcinoma_PRAD_TCGA-2A-A8VL-01A-21R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
low-set ears	HPO Gene-Disease Associations	1.0	null
intracellular organelle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.625206
H3K79me2_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OOBJ-0008-SM-3NB26	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92274
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
431_AQR_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.12266
GSE185944_2_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain - Spinal cord (cervical c-1)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.362
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826142
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.892762
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
fatty acid metabolic process	GO Biological Process Annotations 2015	1.0	null
Icthyosis	DisGeNET Gene-Disease Associations	1.0	null
posteroventral (inferior) parietal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.851094
Liver Diseases	CTD Gene-Disease Associations	1.0	1.48684
hsa-miR-4282	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
BRD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71249
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.67331
GSE210885_0_v_1_klf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Zellweger-Like Syndrome	DisGeNET Gene-Disease Associations	1.0	null
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
r2 part of prepontine raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24525
BRD-K23316938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57288
midbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.133582
muscular hypotonia	HPO Gene-Disease Associations	1.0	null
PMC11821528-41588_2024_2050_MOESM12_ESM.xlsx-MR-Unnamed_2_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
cellular lipid metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE158834_10_v_9_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K18737347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18595
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00735
salivary gland	GTEx Tissue Gene Expression Profiles	1.0	0.898275
NFIC_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K59517185	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1078
LNCAPCLONEFGC	CCLE Cell Line Gene CNV Profiles	-1.0	-2.26748
GSE176093_2_v_3_mineral oil_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Tuberomammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03889
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
atherosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.269208
BRD-K59250830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46684
GSE227698_2_v_4_g0s2_human	RummaGEO Gene Perturbation Signatures	1.0	null
6709_PPY_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.744468
myeloid progenitor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074066
GTEX-WYBS-0926-SM-3NM94	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992846
TET1-21490601-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
report	GeneRIF Biological Term Annotations	1.0	null
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.932318
MGME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62792
ZBTB33_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE171292_5_v_2_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
fatty acid oxidation	GO Biological Process Annotations 2025	1.0	null
Paramedian lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.10156
GTEX-S4Q7-0003-SM-3NM8M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835864
GTEX-WL46-0011-R7A-SM-3LK7X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01075
JHU022	DepMap CRISPR Gene Dependency	1.0	2.67841
Entorhinal area, lateral part, layer 2a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24278
CRCGN015_HEPG2_48H:H04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03773
Insulin Resistance	CTD Gene-Disease Associations	1.0	1.08868
Plant cuticle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.809
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A550-01A-61R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A42030853	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38292
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.26099
POLR2A_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.97815
496100478_HIP_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.10003
USF1_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Acute Kidney Injury	CTD Gene-Disease Associations	1.0	1.53796
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tet1_21295276_mesc_v6.5_lof_mouse_gpl6887_gse26900	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.189611
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal respiratory function	MPO Gene-Phenotype Associations	1.0	null
GSE199921_1_v_0_romidepsin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9342
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02532
decreased body weight	HPO Gene-Disease Associations	1.0	null
496100324_FWM_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.20643
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal postnatal growth/weight/body size	MPO Gene-Phenotype Associations	1.0	null
YY1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
MRPL19	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00601467
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069304
Brain Diseases	CTD Gene-Disease Associations	1.0	1.02559
Abnormal Palate Morphology	DisGeNET Gene-Disease Associations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1PU-01A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
eed_20123906_mouse_embryonic_stem_cell_lof_mouse_gpl1261_gse19076	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.960954
GSE158834_2_v_4_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
KYO1	DepMap CRISPR Gene Dependency	1.0	4.40243
abnormality of the ventricular septum	HPO Gene-Disease Associations	1.0	null
GTEX-R55F-1726-SM-2TF4R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84091
PANC1	BioGPS Cell Line Gene Expression Profiles	1.0	1.28793
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3466-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K32235162	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23024
EP300_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular lipid catabolic process	GO Biological Process Annotations 2015	1.0	null
5005_METTL4_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.563254
medial (main) part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07077
bounding membrane of organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.004469
GTEX-S7PM-0008-SM-3NM9Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71756
GTEX-O5YT-1426-SM-3MJHC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921318
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.929671
KOPN-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100584_HIP_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.38457
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Lung adenocarcinoma_LUAD_TCGA-75-5147-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kinetoplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.788
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TML8-0008-SM-4DXUI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06734
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YV-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null