association	dataset	threshold value	standardized value
GOSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9172
GSE193258,GSE193259_2_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SPATA25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04007
KRT17	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00869081
GSE234340_1_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11426526-ppat.1012555.s011.xlsx-DEG_MDDC_Jurkat_LPS_vs_MDDC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE233679_12_v_13_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CD28	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00849657
GSE183327,GSE183328_3_v_0_ddit3_human	RummaGEO Gene Perturbation Signatures	1.0	null
KRAS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0059882
BRD-K53772256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25364
BRD-K92167240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04692
TRPV6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00785119
BRD-K52566202	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06601
GSE162276_4_v_3_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PPP1R37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36727
GSE111247_14_v_10_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AM095	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.22
GSE202434,GSE202438_2_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
UHRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34862
CCNE1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00472091
BRD-K95578456	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72737
APBA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00522198
BIN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00978946
BRD-K31834149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95869
TAF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51107
GSE106170_1_v_0_nap1l3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE114690_1_v_3_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PRKAR1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00470286
BRD-K95839423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.22137
GSE226114,GSE226116_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K69922285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.35317
BLTP3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0062246
GSE119564_2_v_3_zfp217_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE114992,GSE114993_1_v_6_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE173873_4_v_6_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE155800_1_v_0_imatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FYN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00831667
GSE114883_0_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE178340_1_v_3_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NELFB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00672731
UBQLN4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00604726
THPO	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00687338
IL12A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00807416
MFSD13A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0053573
POLH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00470976
BRD-K07486034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61293
GTEx Skin 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	1.0	6.10393
HC 030031	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.47
GLRA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00627964
ZDBF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51374
GSE123734_1_v_0_mien1_human	RummaGEO Gene Perturbation Signatures	1.0	null
DOCK4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00681686
WBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29136
GSE173997_1_v_0_clic4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K18391257	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18816
CD300E	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00519308
GSE186287_2_v_0_ufm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158834_1_v_3_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE130383_1_v_3_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12055596-41375_2025_2570_MOESM4_ESM.xlsx-PDX1-Unnamed_14_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K36531580	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82292
GBP7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00633641
GSE226408_1_v_0_inpp4b_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100666_HIP_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12609
GSE178532_2_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
NBN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00760577
RPS6KB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00630924
BRD-K87193132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26891
Reproductive organ benign neoplasm	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.001
GSE158834_1_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K99755021	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73018
ITPA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00637131
CRCGN015_MCF10A.TP53.M_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3695
MAST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05478
B4GALT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00542068
BRD-K99100679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27705
GSE224556,GSE224557_8_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K69248736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.57429
GSE110440_2_v_3_rad21_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE195514_0_v_1_stk25_human	RummaGEO Gene Perturbation Signatures	-1.0	null
B3GAT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00656531
DNAJC5B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0115301
QPCT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00633222
GSE193177_1_v_0_st266_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
IGLON5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37894
FGG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00533981
FCER1G	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00532892
TGFB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00737718
GSE240468_3_v_2_nfyc_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCOA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00493303
GSE239844_6_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158834_7_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
DLG2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00872476
GSE159473_0_v_1_eif5a2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K40548004	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02975
SPTLC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00692451
BRD-K76788397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.41013
GSE138741,GSE138743_0_v_1_lin28b_human	RummaGEO Gene Perturbation Signatures	1.0	null
UGGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3241
PMC11542230-12985_2024_2548_MOESM4_ESM.xlsx-MR_results-exposure_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12956708-DataSheet1.xlsx-Supplementary_Table_7-Supplementary_Table_6_The_DEGs_from_high_altitude_between_AMS_and_non-eAMS_group_of_GSE75665_TWIST2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE238018_1_v_0_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCAPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64777
GSE155305_3_v_1_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cerebrovascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.827
RPS27A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00709133
GSE137818_3_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PPP1R16B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00589125
GSE122215,GSE122217_0_v_1_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE200839,GSE233826_2_v_4_tnrc18_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213228_4_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE207611,GSE207612_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Plasma membrane-derived chromatophore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.634
SLC27A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0056855
GSE130401_4_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ADSS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00518673
CFHR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00682599
GSE211262,GSE211263_3_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE102505_4_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Primary immunodeficiency disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.004
PDE10A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00511235
GSE112860_5_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PLEKHH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00612404
BRD-K89811208	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15647
BRD-A37523642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2353
WRAP53	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00486536
VHLL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00850818
PMC5927328-NIHMS77085-supplement-Table_S4.xlsx-Table_S4A_LPS_induced_genes_GO-Unnamed_3_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC4815041-NIHMS715090-supplement-Supplementary_Table_10.xlsx-CCF_DP_clustering-Hugo_Symbol_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE171837_1_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.71475
GSE114992,GSE114993_7_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VPS37B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00497541
PLPPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07347
GSE255432_6_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE148066,GSE157787_5_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K73357010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87468
GSE229580_2_v_3_creb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202825_2_v_1_ano1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE215351,GSE215794_1_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H4C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01091
ERO1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00766247
CRCGN014_HEPG2_3H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13675
PSMB8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00423893
BRD-K70923850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01619
FOXM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00769349
BRD-K11859767	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.11795
CPNE3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00479564
BRD-K04786080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28209
BRD-K76910883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12805
GSE216540_10_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K89063617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54833
GSE239844_11_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MPZL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00569245
BRD-K46376359	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75507
IL1RN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00713679
GSE171352_2_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEx Heart 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	6.76976
GSE160817_0_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE219195_4_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
SGPP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00922325
SVEP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00787291
MED13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00798412
GSE193402_0_v_2_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ALOX15B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0071894
GSE188382_2_v_0_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LRRC37A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00923265
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.0286
GSE221577_1_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RAB40AL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97934
BRD-K24271020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00464
Melancholic depression	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.985
PDE6G	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00683141
W-13 HCl	DeepCoverMOA Drug Mechanisms of Action	1.0	0.39
GSE233679_12_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE198165,GSE198166_6_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE155852_0_v_2_apigenin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSTK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00958001
PMC12178829-mmc4.xlsx-Sheet_4-MEG3-KD_Up-GeneName_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE233679_6_v_13_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE85880,GSE85881_0_v_2_tretinoin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K32269272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67212
GSE171486_4_v_6_ddx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A17635048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0463
BRD-K50950731	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58089
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6679
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.9231
BRD-A98714080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56218
KIR2DS4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00600417
BRD-K93044218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21532
GFI1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00379981
PMC9546828-41389_2022_435_MOESM4_ESM.xlsx-Table_S3-Table_S3_Downregulated_genes_upon_ZNF148_knockdown_P_adj_0_05_Fold_change_1_5_ZNF148	Rummagene Transcription Factor Associations 2026	1.0	null
GSE216273,GSE216292_14_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MYEOV	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0107394
ULK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00576959
GSE198165,GSE198166_9_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE102467_1_v_2_pazopanib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF669	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.325
BRD-K96510191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95788
AOX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00512206
GM2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00827505
GSE169356_0_v_3_ivermectin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Brain disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.827
NCIH1755	DepMap CRISPR Gene Dependency	1.0	4.60628
CAV3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00514813
GNLY	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00770873
GSE107505_3_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ACY1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00465822
HAO2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00928478
PMC6347712-pnas.1812449116.sd05.xlsx-iPSC_IRF7_48h_RNAExpress-Gene_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
GSE201309_4_v_7_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
DERL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19376
BRD-K26091803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00694
GSE129725_1_v_5_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K28912195	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91944
GSE153867_6_v_8_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K73808079	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8156
BRD-K73182084	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80952
Bombesin	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.21
TCF25	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00927423
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.001
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5714
ZNF646	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37509
Tolimidone	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.45
GSE158834_1_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.2222
PMC10042887-41419_2023_5742_MOESM3_ESM.xlsx-Table_S3-Table_S3_Differently_expressed_genes_in_HOXB3_vs_HOXB3-_aPCA_HOXB3	Rummagene Transcription Factor Associations 2026	1.0	null
DENND1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00478966
GSE246053_4_v_3_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10361908-10120_2023_1395_MOESM8_ESM.pdf-36-ENSG00000221869_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
NCR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00768848
GSE240386,GSE242143_1_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE197571_2_v_1_foxm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K41719231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01886
NDUFB10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00652406
BRD-K98190019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97906
BRD-A01717111	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29135
TEPSIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04334
NFKBIZ	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00710889
UBL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39363
STK26	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0061431
NUPR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00450115
GSE158834_1_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TNFRSF10C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00660491
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.128
BRD-K94018786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13677
RRP15	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00556096
GSE202434,GSE202438_8_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TPM4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00801156
RP9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00587557
GSE211226_1_v_0_sirpa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
light-harvesting complex, peripheral complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.766
CRCGN015_MCF10A.TP53.M_24H:B11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.16505
INKA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00638262
GSE48812_11_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GRM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00524428
ITGAD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00646738
SIGLEC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00781141
BRD-K44260904	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76528
GSE132313_1_v_0_fosl2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE152441,GSE152442_1_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE103309_2_v_0_ube3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K82064887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01756
GJB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00467682
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202434,GSE202438_9_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Febuxostat	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.37
SYNM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00494648
RPS14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22488
ADAM15	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00687915
GTF2H1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00434657
GSE63048_11_v_6_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MON	DepMap CRISPR Gene Dependency	1.0	2.03598
LPIN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00933742
CALB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00664858
KLF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.6403
FTSJ3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0065026
BRD-K24246830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3014
GSE123943_4_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
STK25	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00355159
CRCGN015_MCF10A.TP53.M_24H:E16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.69795
GSE123943_4_v_5_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ETV5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.006905
LZTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77038
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
UGP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90797
HSD17B1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00875223
BRD-K82107155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50017
Idasanutlin	DeepCoverMOA Drug Mechanisms of Action	1.0	1.01
GSE135352_6_v_4_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KPNYS	DepMap CRISPR Gene Dependency	1.0	3.34443
UF-27-HS98_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.235583
CRCGN014_HEPG2_24H:M14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01289
TRPV2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00653117
BRD-K28122619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60721
GSE144838_7_v_8_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PRMT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00378613
SOD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00392113
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.7364
PGM2L1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00555666
TIGD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00584567
ZNF740	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	112.575
GSE240896,GSE240899_5_v_4_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
LBH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00639931
BRD-K21040167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04015
GTEx Heart 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	1.0	7.86191
BRD-K16355056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25972
GSE212628_2_v_1_mier1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE220914_1_v_0_zdhhc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OV-90 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.864
AKR1C1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00489099
CHMP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08397
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_25_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GLRB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00555028
KCNA10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0106502
Lymphoid tissue	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K99022424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26711
BRD-K83829186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11696
BRD-A52794651	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10784
KLF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	122.329
GSE171175,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Bacteriocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.794
P4HA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00448387
TRPM3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00602634
GSE77108_5_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE182680,GSE182683_7_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
chr11_288883_A_G_b38	GTEx eQTL 2025	1.0	1.04921
BRD-K76588894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89772
PPBP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0064175
DRD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00519962
GSE146982_7_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K21051792	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45966
GSE133213_9_v_15_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158834_12_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VWA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00531929
GSE178340_7_v_3_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNRK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00760706
MPV17	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00732213
Ameloblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.814
FGA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00805282
BRD-K52868251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67099
GPNMB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00533235
ZFP91	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00685486
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.55631
DGAT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00720993
TLR7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00702894
BRD-K78965436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92757
Granulosa cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.97
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.338
BRD-K89065802	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30265
AKT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3388
UGCG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00614378
GSE223008_0_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE156454_0_v_1_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
DDX6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00714836
GSE242083,GSE242098_3_v_4_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PATZ1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	207.891
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.7895
ESAM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0082962
PDE7A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00471168
RAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.598
BRD-K16518464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83764
GSE240258_0_v_1_prmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
IRF8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00714766
GSE107854_2_v_0_prmt5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BCOR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.009223
GSE195582_2_v_1_pim1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K90360779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01212
YARS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00866906
GSE102132_2_v_1_irf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GPX7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00819668
GSE233679_5_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ANAPC15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91092
GSE160817_2_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A92357389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03908
GSE173873_1_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
G6PC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0113544
SLC16A4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00523555
BRD-K82658511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28706
P2RY14	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00672741
FPR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00478589
MPL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00514287
GSE182680,GSE182683_5_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
RAG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0090397
CHRM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00479672
CYP21A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00653791
SERPINE1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00748184
AFD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0104036
GSE233679_14_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
TFDP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.3528
BRD-K27543887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0476
BRD-K67448189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95591
H2AC6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00572981
SRGN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00925092
GSE128730_4_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_10_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K76885311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59688
PATL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0066259
PMC8812561-pnas.2110428119.sd11.xlsx-Sheet1-The_overlapping_genes_of_LCDR_KD_RNA-seq_hnRNP_K_KD_RNA-seq_hnRNP_K_RIP-seq_and_eCLIP-seq_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CCKAR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0043746
Serum alkaline phosphatase levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	7.1
GSE172295_3_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ABI3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00896105
SAR1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00792619
BRD-K65064082	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07244
MICALL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00562286
GSE102505_1_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
IRF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.665
BRD-K43326597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16964
ASIC3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00794427
PMC12430004-ugae028_Supplemental_File.pdf-10-MLXIPL_MLXIPL	Rummagene Transcription Factor Associations 2026	1.0	null
Small intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GREB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00552
SALL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00414175
GSE128730_7_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cervix - Ectocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	1.49349
GSE172146_2_v_0_mettl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GNPTAB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00723862
OAZ1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00464
HMGCS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00446162
GSE111385_2_v_1_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K92655427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9414
GSE233679_14_v_13_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K11516621	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26459
PMC10247733-41408_2023_863_MOESM2_ESM.pdf-31-ATF6B_ATF6B	Rummagene Transcription Factor Associations 2026	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K68078571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12178
CHMP2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0128319
BRD-K69918256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89514
ARL5B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00652895
IRF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00585581
GSE68155_3_v_2_gpr3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BCL11A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00756718
Female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K75263760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2548
SP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56898
KLF10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	113.768
MYCN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5082
PPM1F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0051
ACP5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00705414
FSCN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00562681
BRD-K94993773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06833
BRD-K27356753	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29941
GSE199255,GSE199356_4_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10361908-10120_2023_1395_MOESM8_ESM.pdf-37-CEBPD_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
HLA-DRB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00583235
FHIT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00458213
BRD-K23029982	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18318
SFTPC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00566374
TUBA1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00603665
GSE202434,GSE202438_6_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE216043_11_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SUPT20H	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00585861
PMC9894241-pnas.2211429119.sd05.xlsx-G1_REST-Dataset_S5_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
PDS5B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0098533
PMC12634441-41375_2025_2771_MOESM7_ESM.xlsx-RNAseq-Table_S2_Bulk_RNA-seq_GATA2_vs_control_Only_p-adj_0_05_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE237426_0_v_1_eif4a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K67522096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27545
P2RY13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00714927
MRPL32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02417
ITGB7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00520918
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.3546
BRD-K05154886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59375
BRD-K45762887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85318
CXCL10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00672457
INPP5A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00597262
CALCA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00344844
RPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16936
KCNK15	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00337477
GSE222047_0_v_1_imidazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE226249_5_v_6_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K61753872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44218
RPL37A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31939
GSE182680,GSE182683_7_v_9_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE84148,GSE96938_3_v_1_nrros_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PRXL2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00506434
BRD-K29975122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03986
GSE128730_3_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K73275682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30112
BRD-K27117623	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48567
GSE112860_9_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RHOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07677
COV504	DepMap CRISPR Gene Dependency	1.0	2.63789
PMC5670203-41467_2017_1251_MOESM5_ESM.xlsx-differential_expressed_BCL6_tar-ensembl_gene_id_BCL6	Rummagene Transcription Factor Associations 2026	1.0	null
RENBP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.006143
BPIFA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00595413
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.2759
GSE201309_4_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K76125116	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21811
PMC9218776-ADVS-9-2104640-s002.xlsx-SIM_-_Nurr1-Unnamed_1_SIM2	Rummagene Transcription Factor Associations 2026	1.0	null
PCK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00810327
BRD-K96764878	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31717
CRCGN017_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.43895
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.879
GSE96649_1_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SH3BP5L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00485027
GSE135350_3_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC5903287-NIHMS956886-supplement-Table_2.xls-THP1_THP2_cds_exp_down-gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
DTP3_A-427	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0161277
PSMB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00684531
GSE102870_3_v_0_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DDAH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00797572
TFDP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00545264
CHEMBL1597046	DeepCoverMOA Drug Mechanisms of Action	1.0	0.5
PIKFYVE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31473
GSE184210_0_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
STAB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00502002
GSE158456_2_v_3_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
DSCAM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0107539
PMC9618568-41467_2022_34255_MOESM5_ESM.xlsx-TAL1-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE114992,GSE114993_9_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K95153427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52318
GSE169691_1_v_2_saha_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE210667_1_v_0_rfx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE240896,GSE240899_10_v_0_ccnt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE164874_5_v_1_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PAOX	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00498025
TNK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00507459
BRD-K27754030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.48693
BRD-K00628863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45435
Actin cap	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.272
COX7A2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90685
docebenone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57781
GSE226285_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
IPCEF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00879226
CRCGN014_HEPG2_3H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0358
GSE190316,GSE190324_1_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
NFKB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.2885
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.39772
Racecadotril	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.34
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_name_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE213228_4_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE264621_1_v_6_secretin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VSTM2L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0059527
BRD-K82729862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8226
BRD-K86888602	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28157
PLAGL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.9009
BRD-K67406305	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50717
NDUFA5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00572872
GSE235390_4_v_0_lurbinectedin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ASGR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00676914
BRD-K91003483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48194
BRD-K67146164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01444
BRD-K06029218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.19296
GSE199921_1_v_0_romidepsin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
VSTM4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00491507
AMT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0054567
GSE149943_2_v_0_cd8a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K46121327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14181
CFH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00772066
GSE172494_2_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE191015_0_v_2_gsdmb_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE200839,GSE233826_2_v_6_tnrc18_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216273,GSE216292_0_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HSD3B1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0111894
Spleen	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
STX3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00796674
ZNF460	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	123.158
SYNCRIP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00489371
PDGFRB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0111909
GSE95077_5_v_3_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE178340_7_v_2_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE188570,GSE188571_3_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE155031_5_v_3_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.8279
PMC8481886-Table_1.xlsx-A_subsets-iMSC_fetal_MSC_UC_MSC_bone_marrow_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
ANGPTL4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0081234
PANX3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00674383
TMEM266	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00901203
X-linked hypoparathyroidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.637
AMIGO3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00445579
TUBD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00661555
SLC12A9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00747323
PNKD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0065904
B800-850 antenna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.683
MCF2L2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00717345
U2904	DepMap CRISPR Gene Dependency	1.0	2.75338
GSE245418_0_v_2_cd109_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148200_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE247764_3_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K20039572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59585
GSE166315_2_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216043_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PHYKPL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00872036
GTEx Thyroid 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	6.59932
GSE192771_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K83272071	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24411
GSE164874_5_v_11_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE184902_3_v_0_adipor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ARHGDIA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00882409
GSE184356_1_v_2_tfam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.2727
PRKAB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00619971
GPR179	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00385023
CRCGN016_MCF10A.WT.HP_24H:F16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.44411
ARIH2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00355758
GSE178340_5_v_3_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE129389_0_v_7_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K62983405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.65101
BRD-K73574487	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54717
IP6K1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00826088
BRD-K59194147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4456
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_id_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
HDAC4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00635419
SLC5A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00551502
GSE130383_2_v_0_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HAVCR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00660745
EGR3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	91.8092
BRD-K70057550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10488
Intestine	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Cytotoxic T-lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.838
MAST1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00714964
SLC9B1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00653627
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.3462
P4HTM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02086
BRD-K10876822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.72526
GSE160817_3_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
OLFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05065
GSE160817_4_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE138633_2_v_0_bag3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE171486_4_v_0_ddx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL2-Unnamed_0_TAL2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12500934-41408_2025_1358_MOESM3_ESM.xlsx-Table_S6-DEGs_p_0_05_between_surviving_or_deceased_DLBCL_patients_that_received_R-CHOP_therapy_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
GTF2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38153
XCT 790	DeepCoverMOA Drug Mechanisms of Action	1.0	0.32
TREML2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00883916
GSE137914_4_v_5_tet3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE153341_2_v_3_atf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PLAG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	137.0
BRD-K02802091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7654
CYTH4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00743159
CARD14	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0106609
GSE199204,GSE211619_4_v_2_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GIMAP4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00521051
H6PD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00643633
GSE127790_5_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TADA2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0060334
GSE237040_0_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE154577_7_v_12_plagl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142588_2_v_1_cinobufagin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE162276_5_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Small intestine	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K49908787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32326
Heart disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.237
CEP72	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00612568
DAPK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00592465
GSE159049_3_v_0_sox2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GLI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.2733
BRD-K77627909	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54533
BRD-K63787803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58471
GSE239784_1_v_0_sat1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RASD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0936
SC 560	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.3
LTN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00515852
GSE184399_0_v_2_cnot1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CLEC2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00480712
OCIP5X	DepMap CRISPR Gene Dependency	1.0	2.08716
DPYSL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00518595
BRD-K80965028	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.91853
RTL8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13651
CXCR6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00524351
GSE154767_2_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCOLN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0059404
GSE128076_1_v_3_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Organ system benign neoplasm	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.001
BRD-K45348630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18654
Batlung	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.149
FKBP11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00656103
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_upreg-human_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K37564297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16038
LDHC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0061941
Serotonergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.27
DKC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82138
ZNF638	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01807
PEX14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66434
HAT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00357366
BRD-K67874412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45789
BRD-A91461229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00094
TRIM46	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00550728
GSE138818_1_v_3_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K09405682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17363
GSE213715_0_v_1_iqgap2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RPL37A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00748723
SNRPA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.011403
BRD-K57382977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.18501
GSE196671_5_v_0_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AFG3L2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00565107
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.1328
GSE171269_1_v_3_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NSC735380	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.32
GRPR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0091582
HIVEP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00903
AIF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00701092
GJA5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00509571
PLPP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44304
OAW42	DepMap CRISPR Gene Dependency	1.0	2.7079
GHRL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0077359
Prostatic hypertrophy	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.451
BRD-K43341819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00311
GZMA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00703846
SHI1	DepMap CRISPR Gene Dependency	1.0	2.24353
PMC9314667-Table_1.xlsx-Regulons-ETV4_ETV4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11602576-mmc11.xlsx-ST12-Table_S12_Output_of_mash_model_of_milk_and_GTEx_eQTL_effects_Related_to_Figure_2_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K31778201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35279
GSE146982_7_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PROCR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00661123
mRNA cleavage and polyadenylation specificity factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.706
WT-8 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.459
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE135350_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
FFAR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00526775
ROCK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0100394
BRD-K31297909	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24758
GSE111385_0_v_1_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IFNG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00724918
496100618_PCx_probable Alzheimer's disease_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.57763
PTRH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0042234
HDAC5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.010011
RIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04326
GSE207914_2_v_6_nudt7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CLEC11A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0117938
GSE182680,GSE182683_10_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF-31629814-HEPATOCYTES-MOUSE-TYROSINEMIA	ChEA Transcription Factor Targets 2022	1.0	null
CTSC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00602919
WDR76	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56202
GZMK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00564941
BRD-K78812892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08233
BRD-K16364953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63731
GSE109530,GSE109531_1_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0121
C16orf87	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42829
GSE234340_9_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE128076_1_v_0_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SPNS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5917
DHPS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00557923
NPM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0058321
TRPM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00611117
BRD-K04426746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06378
PMC3226433-1756-8935-4-20-S1.XLS-Table_S4_Myc_KD_gene_exp_change-Genes_down-regulated_in_Myc_KD_hESC_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE246911,GSE246913_4_v_1_arid1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205070_1_v_6_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KLF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.1712
COL7A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00521333
SLC45A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0039844
CRCGN016_MCF10A.TP53.M_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.17563
ITPKC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0054775
HSD17B4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00681778
GSE193402_0_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE148066,GSE157787_11_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NDUFS4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00537905
DDRGK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00466431
Bursa of Fabricius	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.741
BRD-K94301203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42707
CRCGN012_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.121
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52639
GSE159678_6_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K28803288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22671
PCIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07678
TRIP10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00530087
HUWE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21814
GSE145311_1_v_3_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CDK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0068215
KIF5A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00664163
GSE128730_7_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE135350_2_v_7_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
MOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22298
PMC12126244-jci-135-184115-s239.xlsx-Table_3_Suppl_Fig_16-Genes_down-regulated_in_SOX9_low_tumors_744_genes_SOX9	Rummagene Transcription Factor Associations 2026	1.0	null
Uterus	GTEx Tissue Gene Expression Profiles 2023	1.0	5.71058
ORM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00523306
BRD-K32049721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51634
GSE160817_5_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DACH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00478398
WEE1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00415621
BRD-K63436213	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.23764
GSE234340_10_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZBTB7B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5781
GSE216540_1_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE242290_3_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE114992,GSE114993_7_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K29838935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26003
PMC9218776-ADVS-9-2104640-s002.xlsx-SIM_-_Nurr1-Nurr1_modulation_mediates_neuroprotective_effects_of_statins_SIM2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K66479240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.65133
BRD-K84241565	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22755
GLIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.6126
GSE197571_3_v_1_foxm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE111247_2_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
TEN	DepMap CRISPR Gene Dependency	1.0	2.41695
NEK11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00415931
GSE202434,GSE202438_4_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Endocrine system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.004
PLCD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0094253
NAE1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00348295
CA8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00744132
GSE214583,GSE214585_1_v_0_steap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
KIR3DL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00548942
UTP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31829
FASTK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00717837
BRD-K60064462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2027
TFAP2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	173.427
GSE174751_0_v_1_postn_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149870_0_v_1_pfn1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN009_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.30476
BRD-K66270896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.706
FOLR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00835597
BRD-K47200630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46093
SP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	145.2
Spi1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	78.9211
HIPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56382
ZNF263	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.0964
GSE105169,GSE105175_0_v_1_dhx36_human	RummaGEO Gene Perturbation Signatures	1.0	null
KDELR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00838613
BRD-K10423475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39265
PMC13127299-mmc2.xlsx-PBX1_kdRNAseq-hgnc_symbol_PBX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE207514,GSE207515_2_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K95323755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60759
GSE74251_0_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE155836,GSE155839_3_v_2_alvocidib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PIGA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00661527
GSE156907,GSE160237_1_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE228181_4_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K61247793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36114
GSE151090_0_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	1.0	null
TFAP2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	194.656
PIWIL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11813
DEFB4A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00517344
GSE199255,GSE199356_6_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Depressive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.985
CHRNA7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.007554
FPGS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00441986
ZNF814	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14722
HAX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00761874
GSE236003_1_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CERS6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00538341
BRD-K27398402	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07523
TAOK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00760957
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.4035
PRORP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84699
MAP3K3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00659911
chr11_295808_A_G_b38	GTEx eQTL 2025	1.0	4.01894
GSE174406_2_v_1_lin28b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K42367391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52329
CRCGN014_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.0358
GSE179880_10_v_13_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE168697_0_v_1_wdr6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MBD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.005084
KMS11	DepMap CRISPR Gene Dependency	1.0	3.05125
BRD-K41031262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33579
BRD-K16802067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42802
BRD-K53768630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98041
BRD-K30921693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.46224
GSE197555_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZCCHC12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00482729
FARSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17614
PCK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0067531
PDCD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72488
HIPK4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00795324
NXT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18522
BRD-K66222602	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77037
GSE233112_2_v_0_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GZMM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00599469
GSE138818_1_v_0_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE132369,GSE132371_3_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.6871
CAPN15	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00849991
BRD-K01606969	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.966
PMC10117100-msphere.00056-23-s0008.xlsx-2B-Supplementary_Table_S2B_mRNAseq_analysis_genes_significantely_downregulated_upon_E2F4-5_knockdown_in_38HK_E2F4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE162276_4_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RPH3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41422
ML349	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.26
GSE172295_4_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K20520611	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56943
GSE159049_1_v_0_sox2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BLNK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00706745
SETD1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00428603
ADAM19	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00703527
GSE246184,GSE246195_0_v_1_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PTGER1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00931971
BIN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00784669
KLK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00608616
NR2C2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0089857
GSE162276_5_v_3_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ADAMTSL3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00946059
GSE140607_1_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE183327,GSE183328_1_v_0_ddit3_human	RummaGEO Gene Perturbation Signatures	1.0	null
AADACL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00798763
PMC12055596-41375_2025_2570_MOESM4_ESM.xlsx-PDX1-Unnamed_13_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
CELF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11886
GTEx Thyroid 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	1.0	5.22095
SNUPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77579
GSE171837_0_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE190186,GSE190188_0_v_10_apoe_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216043_10_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE196835_0_v_1_ddx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
LS1034	DepMap CRISPR Gene Dependency	1.0	2.79575
Cognitive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.985
PRDX5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00642936
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.7778
SNU685	DepMap CRISPR Gene Dependency	1.0	2.11751
KLF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.1758
BRD-K62182950	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64794
GSE239844_7_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BACE1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00448594
RNPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3886
HAVCR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00570216
NCIH2087	DepMap CRISPR Gene Dependency	1.0	2.44262
GSE127790_6_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE129389_0_v_5_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE181003_3_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
EPHA8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0054288
H4C5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00618436
B800-820 antenna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.908
LCN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00409741
BRD-K93817456	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43321
Reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.001
CCDC152	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61193
REST	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.269
ACSM2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00607629
BRIX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00659059
GSE135350_3_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE152637_1_v_0_imiquimod_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K42016545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09997
BRD-K48827674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.64446
MAC2A	DepMap CRISPR Gene Dependency	1.0	3.6392
GSE234514,GSE234516_1_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SLC2A4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00792765
CD68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18033
OGFOD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00471496
CRCGN015_MCF10A_48H:K12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.32641
PMC7217064-IJC-146-3354-s005.xlsx-Table_S6-Supplementary_Table_S6_Genes_significantly_upregulated_in_OC2-transfected_MKN74_cell_compared_to_control_ONECUT2	Rummagene Transcription Factor Associations 2026	1.0	null
ATP5IF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38862
ZNF454	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	192.698
Ar	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.5654
PMC9601604-NIHMS1841143-supplement-SuppTable-2.xlsx-FOXO3-specific_targets-FOXO3-specific_targets_1218_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
MAST2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00427533
GSE158834_7_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE110248_1_v_6_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8314029-12931_2021_1797_MOESM5_ESM.xlsx-DE_genes_in_ACDMPV-Gene_stable_ID_FOXF1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K63579322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2709
GSE199204,GSE211619_4_v_6_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9013128-NIHMS1795992-supplement-4.xlsx-501mel_ARID2_KO_Downregulated-Gene__name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K33350866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03932
BRD-K87264606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2019
GSE242333_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K45343543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05418
GSE160817_7_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE152050,GSE152052_1_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K27618188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53829
BRD-K43570522	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97208
BRD-K86923998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35715
IRF5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00793249
MDAMB453	DepMap CRISPR Gene Dependency	1.0	3.3019
BRD-K85234739	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.3995
BRD-K89364982	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91982
RBM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13269
CDC42	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00613747
PMC4686761-ncomms10068-s3.xlsx-S2G-MSC_down_specific-Supplementary_Data_2G_-_expression_of_down-regulated_genes_2_fold_change_specifically_in_MSC_PTEN-_-_vs_MSC_PTEN_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
SLC30A4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00734688
ZNF490	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99977
GSE112202_5_v_2_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K85162396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77131
BRD-K03352392	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18491
RUNX2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00577252
SV2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00820947
SPHK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00569356
GSE228261_0_v_1_elesclomol_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC4595011-pgen.1005555.s003.xlsx-BPTF_DOWN-regulated-Gene_name_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
AK9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00670878
GSE190316,GSE190324_6_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE109530,GSE109531_1_v_0_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
B875 antenna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.429
ZNF705A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73682
ACVR1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00596836
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2416
MAP1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00504592
DRD5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00804503
GSE214212_2_v_0_chd6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Rimonabant_A-427	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0228289
GSE128076_2_v_3_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.044
BRD-K75293299	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99699
GSE128730_7_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Meloxicam	DeepCoverMOA Drug Mechanisms of Action	1.0	0.22
ASGR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00825443
BATF2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00558221
PKLR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00699198
UQCRC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00747981
GSE145990_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PGD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98568
GSE199255,GSE199356_6_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
S100P	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00661142
GSE201217_4_v_6_usf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
STK4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00641797
CRCGN017_MCF10A.WT.HP_24H:B07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2864
AMY2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00705593
BRD-K09324395	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46959
FPR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00533616
BRD-K75252192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01883
ASNS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00364287
CDC37	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00674449
LNPEP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00475008
GSE120612_4_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Stomach	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE188570,GSE188571_3_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K07996284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.18664
GSE172494_3_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MHHNB11	DepMap CRISPR Gene Dependency	1.0	2.32073
CCDC34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75946
GSE87299_1_v_0_nr1d1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HIPK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00719583
MUC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00421229
GSE116299_4_v_3_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K18179332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16256
GSE158834_2_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAPK7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0053535
GSE110268_2_v_3_foxd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211983_0_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NDUFA8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00593558
RYR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00540403
TUBA8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00477851
BRD-K65860773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53167
GSE102486,GSE102490_1_v_5_setdb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE243879_1_v_0_elapor1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.0566
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.9807
SREK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03085
ACADM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00883995
BRD-K06480376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97078
AS-605240	DeepCoverMOA Drug Mechanisms of Action	1.0	0.31
BRD-A76904477	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00039
GSE116930,GSE116935_3_v_6_hes7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC78	DepMap CRISPR Gene Dependency	1.0	2.77598
RCCFG2	DepMap CRISPR Gene Dependency	1.0	2.11971
BRD-K98595604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.26026
CCNH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00467656
FADS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00619561
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2174
KIF3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00527752
GSE188458_2_v_4_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	1.0	null
RPL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72369
VSIG4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00585088
EXOC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04491
Breast	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PANK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00681787
GSE97352_1_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE114883_1_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PRM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00818449
BRD-K52123365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00509
GSE102870_7_v_0_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K26237438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05658
CRCGN010_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.98795
ZACN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00567427
GSE169356_2_v_4_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ATG16L1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00650738
GSE234340_4_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE184210_0_v_1_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
KLF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.9893
CHRNA3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00529158
TSC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00565478
PMC9911396-41467_2023_36178_MOESM11_ESM.xlsx-Sheet1-Genes_in_10kb_vicinity_of_ZBTB12_ChIP-seq_peaks_ZBTB12	Rummagene Transcription Factor Associations 2026	1.0	null
KCNH5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00564009
BRD-K93335719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54276
PMC12183081-41388_2025_3375_MOESM8_ESM.xlsx-Sheet1-Table_S7_List_of_differentially_alternative_splicing_genes_in_osteosarcoma_cell_lines_after_knocking_down_the_YBX1_gene_P_0_05_Related_to_Fig_6C_YBX1	Rummagene Transcription Factor Associations 2026	1.0	null
CYP2E1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00673743
GSE234340_10_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6195
BRD-K64632606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.09525
GSE210101,GSE210114_2_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158834_7_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE208254_4_v_2_irf8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OR10S1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00656705
BRD-K65705295	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03903
BRD-K94344573	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46074
NAIP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00759236
ADAM28	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00650784
IL15	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00589569
PMC9618568-41467_2022_34255_MOESM5_ESM.xlsx-TAL2-Unnamed_0_TAL2	Rummagene Transcription Factor Associations 2026	1.0	null
CAD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0051209
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.001
PHF5A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00518053
B2M	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0066269
BST2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00570031
GSE169152_5_v_7_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE182680,GSE182683_7_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K44908880	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56099
GABRG3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00679804
BRD-K01100412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5424
PGGT1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23757
AMZ1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00614681
PIK3C3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00613968
Major depressive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.985
GSE125211_2_v_3_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K10862230	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03951
GSE128076_2_v_0_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CDC42SE1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00355953
GSE198165,GSE198166_5_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CYSLTR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00660075
Plasma membrane light-harvesting complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.671
HSD17B10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00723643
ADAM10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00530331
Liver	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NTSR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00568309
BRD-K58932103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75694
GSE135030_3_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Benign neoplasm	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.001
BRD-K14853757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20233
GSE234340_9_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7215
CRCGN017_MCF10A.WT.HP_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.20475
GSE216538_7_v_2_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DENR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00774114
GPR157	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00473193
MSI2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00557283
GSE253089_0_v_1_ephb2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LSP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00487799
BRD-K95014616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56911
496100584_HIP_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01727
GSE199092_3_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CACNA1I	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00526353
DVL3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00369907
PMC6344081-elife-40364-supp8.xlsx-PLZF-Si-diff-expressed-genes-Up-Symbol_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
CTNNBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30021
GSE182680,GSE182683_5_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CCR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00629157
BRD-K59893572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.86208
ZBED4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	114.583
GSE135350_2_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE168602,GSE168604_2_v_6_selumetinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K21253219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19938
IL17F	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00992175
GSE252988_0_v_1_lefamulin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Bruck syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.371
GSE205687_1_v_0_mta1_human	RummaGEO Gene Perturbation Signatures	1.0	null
QRICH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00742416
GSE158834_10_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DOK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00622459
FGGY	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00638027
CIITA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00868811
FBLN5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00535389
BRD-K71970681	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36231
ENTPD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0089121
PDE8A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00452816
CRCGN017_MCF10A.TP53.M_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07161
CD79B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00853138
GSE62843,GSE64370_0_v_1_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CYP11B2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0100511
SLC6A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0070971
GSE173873_1_v_6_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K35222206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01579
carbohydrate metabolic process	GO Biological Process Annotations 2025	1.0	null
CRP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00824041
BRD-K67337799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45929
Alimentary canal	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Autoimmune disease of endocrine system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.004
Gli2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.5108
WAPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96385
CRCGN015_HEPG2_48H:F17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.04503
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.5776
Gli1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.7414
GSE191105_2_v_4_nat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TNIP3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00539424
GSE184892_0_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HSPB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20807
GSE155031_5_v_0_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
KLF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	111.807
BRD-K96747266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04184
KCTD20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36934
GSE113817_2_v_1_bach1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Endocytic vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.988
BRD-K30488928	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48155
DPPA4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00581718
HDAC10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00540842
GSE48812_9_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE172016_2_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CD320	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00412883
VAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28723
GSE208254_4_v_5_irf8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE201309_4_v_6_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K84710243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02864
FAM156B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.59013
PDS5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14856
BRD-K71141540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50121
GSE144838_1_v_8_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157894_1_v_3_cystine_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100336_TCx_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.18684
CD300LG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00704137
BRD-K12683022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86216
GSE234340_1_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HES1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4883
GSE160817_4_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SET2	DepMap CRISPR Gene Dependency	1.0	2.17387
STAT3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00396317
PRM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00780219
GSE213588_8_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE198165,GSE198166_0_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CPT1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00631507
BRD-K29328556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71001
GSE239844_8_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K17176016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.71781
BRD-K98529522	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.72259
MTTP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00663626
CRCGN017_MCF10A.WT.HP_24H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.12669
HAPLN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00448704
TRIM69	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00528792
SPP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00355911
OVOL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00621279
VEZT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01412
GSE128730_3_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GP9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00600281
POLE2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00414914
EREG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00671179
BRD-K30491662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01945
GSE107505_1_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K11581306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.45586
BRD-K51577639	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02409
GSE102870_11_v_0_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.7822
GSE160817_7_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE168918_1_v_0_tmprss4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GLIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.2282
GSE216326_2_v_0_sulodexide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K27109474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62647
EGR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.4293
496100320_PCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.13071
CRCGN015_MCF10A_48H:H23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15958
MEI1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00721638
BRD-K84936524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01271
BRD-K31021810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.31657
MEF2D	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00465148
DLG5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0105154
PKD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00673266
GSE193993_1_v_3_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.985
GSE226584,GSE226589_2_v_0_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K92246187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15227
ZNF416	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39816
BRD-K58963469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8825
TNFRSF14	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00520718
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
ATXN7L2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0124433
GSE111247_11_v_10_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K27352194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44365
GSE233679_6_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Trophosome tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.572
CRCGN009_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.5533
GRIN2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00530359
AIRE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00871611
GSE199255,GSE199356_6_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.138
APOBEC3G	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00818792
SRM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00859926
BRD-K60907484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06226
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.3225
C4BPA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00719143
CYP3A5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00872255
GSE164874_5_v_9_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
SCN4A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0082104
SLC26A9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00453017
GSE142430_3_v_0_prmt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
NQO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36652
GSE158834_7_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
SIGLEC9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00603891
NB10	DepMap CRISPR Gene Dependency	1.0	4.18812
BRD-K44858727	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56908
GSE197555_0_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
A 438079	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.37
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.7086
(S)-Selisistat	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.6
BRD-K11433244	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06434
ILDR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00548112
GSE179002_2_v_7_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SKNDZ	DepMap CRISPR Gene Dependency	1.0	2.38771
GSE154577_6_v_12_plagl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
VEZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.1966
BRD-K03304013	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27378
CTCFL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.8536
GSE138019_4_v_5_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SETX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0347
BRD-K67998155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.87756
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157F_vs_MSX1-Gene_id_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
P3H3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00506877
CALU	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0039467
SRF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0049357
BRD-K42061172	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.46377
FOXA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00652623
GSE114992,GSE114993_9_v_6_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GALE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09993
GSE132369,GSE132371_1_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE207471_2_v_3_btla_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE58724_3_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
chr11_287959_G_A_b38	GTEx eQTL 2025	1.0	2.4717
TIAM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00687926
GSE206516,GSE206518_3_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE174418,GSE174421_2_v_3_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
UMNSAH/DF-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.617
BRD-K20895937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08033
SBK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00530478
CLK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0116371
Plume	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.648
GSE168604,GSE183859_1_v_0_selumetinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K05804651	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72831
GNA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17652
GSE141726,GSE141733_1_v_0_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TICAM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00756641
BRD-K61551386	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16935
ATF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51094
BRD-K51654114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33698
CRCGN013_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.47402
SLC11A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00986321
ZNF692	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.0142
GSE198165,GSE198166_8_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BCL10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00580911
KCNQ1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00654676
BRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05357
BRD-K32191695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06489
A172	DepMap CRISPR Gene Dependency	1.0	7.13302
BRD-K90127029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00379
MTHFR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00514964
BRD-K94913575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91382
GSE179002_0_v_7_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K94742710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19512
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.0424
GSE216043_10_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CRCGN017_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.26019
GSE48812_0_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
ATG4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35855
GSE118794_5_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158431_5_v_7_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE201042_2_v_3_ptpmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOSL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00688416
BRD-K47865468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01476
GSE181003_3_v_2_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE95688_7_v_2_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MOB3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00678138
GSE159148_0_v_1_sdc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
INS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00606456
PMC12339377-41587_2024_2403_MOESM3_ESM.xlsx-TableS6_LPS_screen_GEPs-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K58237252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06849
GSE233679_5_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE107505_0_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HAS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35119
ACACA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00637686
GSE184902_4_v_0_adipor1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K93752373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.306
GSE233679_14_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
IGSF3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.011442
GSE115328_6_v_7_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72397
PMC8185471-mmc4.xlsx-D2-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_2_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
ADCK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00661695
GSE116492,GSE116495_3_v_2_stag2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE166315_1_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE228413_2_v_5_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NLRC4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00473804
GSE169617_1_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PTGFR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00571593
CHKB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00708234
VEGFA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0057154
SMARCA4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00588323
YES1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00737666
GSE155305_3_v_0_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
E2F7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00966679
PNPO	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00810087
CRCGN015_MCF10A_48H:H16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06526
PMC9882185-media-2.xlsx-All_B2-AR_targets-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE247764_5_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
22RV1	DepMap CRISPR Gene Dependency	1.0	5.23203
GSE234340_12_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Other source	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.1
GSE199255,GSE199356_4_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PADI3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00491007
GSE129370_2_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.36165
IFNGR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00792522
GSE216043_10_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
YTHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19058
GSE122990,GSE123061_0_v_1_urod_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HEPACAM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00497792
Prostatic urethra	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.606
KLF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	98.1102
GSE153867_6_v_3_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100647_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.10666
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_CCRFCEM_ChIP-seq_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
GLIPR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0049341
PMC4595011-pgen.1005555.s003.xlsx-BPTF_DOWN-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
QKI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0532
SP8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.259
APEH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00765657
ARFGAP3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00473417
PMC11663789-mmc6.xlsx-B_cells-MMP4_AA_Metabolism_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
PLA1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00654924
GSE158431_2_v_3_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HOUAI	DepMap CRISPR Gene Dependency	1.0	2.5479
GSE193993_5_v_2_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_10_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K72561299	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15958
BRD-K61354976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69823
BRD-K05549579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.36514
NB7	DepMap CRISPR Gene Dependency	1.0	2.24527
HAPLN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00510623
BRD-K59356638	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77056
GSE223334_1_v_2_bcl11b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146074_1_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CD200R1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00983807
GSE92589_0_v_1_sirolimus_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6604319-13072_2019_278_MOESM3_ESM.xlsx-CEM_ect_TET2_DEGs_DMRs_hDMRs-Unnamed_4_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158834_12_v_4_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HLA-DOB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00542503
GSE182680,GSE182683_5_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE140607_3_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZBTB38	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00716786
GSE120413,GSE120447_0_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_EC109_KD-GeneID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HEATR5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11568
RPS20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.58088
BRD-K06784595	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29809
BRD-K79631534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.41566
Tracheal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.631
GSE228413_4_v_3_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SHBG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00499985
AGTRAP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00539914
U2AF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0128708
BRD-K38282015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14975
ST3GAL5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00475704
GSE248858_1_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE239844_6_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K96459367	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01518
BRD-K02517738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25336
GSE152937_6_v_5_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ITGAL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00706349
BRD-K63887881	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74074
FUT8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0059773
LRRIQ3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00641044
MTNR1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00745794
PPID	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00731164
BRD-K90858591	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19003
SAA4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0094477
GSE160304,GSE163392_7_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K38788176	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.18775
EL-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.639
BRD-K23762204	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38663
ZNF320	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	287.275
NANOG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00513559
MARCKS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00712299
aminoglycoside-induced deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.222
CELA2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0121396
PMC11063202-41420_2024_1940_MOESM2_ESM.xlsx-THP1-EP300_KOvsNontarget-gene_name_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
Fumaric acid_A-427	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0236639
Enamel organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.686
G0S2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00549727
BRD-K67211407	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0025
SMC3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0226384
Nanog	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.0641
APOBEC3H	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00766397
BRD7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00559373
GSE133516_5_v_6_kat7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K92913380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94876
ANXA9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00998641
GSE87412,GSE92423_3_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PSG7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00931574
SLC25A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00830288
GSE125211_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GIMAP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0047399
Immune system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
UNC119	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67657
BRD-K77417197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05712
chr11_295876_C_T_b38	GTEx eQTL 2025	1.0	1.90814
RARA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00903456
GUSB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00662304
GSE135030_3_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
AKR1C4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00703584
CTSK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0074565
GSE226249_0_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZFYVE16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30813
GSE158632_3_v_5_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ML-265	DeepCoverMOA Drug Mechanisms of Action	1.0	0.28
BRD-K37625653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1503
G2E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20228
PPP1R15A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00512175
Male reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.451
RGS4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00600192
PF-04620110	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.51
PMC12461113-HEM3-9-e70217-s002.xlsx-Table_S3-Model_2_top_50_genes_IKZF5_IKZF5	Rummagene Transcription Factor Associations 2026	1.0	null
D423MG	DepMap CRISPR Gene Dependency	1.0	3.03135
BRD-K92359570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25824
SRMS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0059458
BRD-K27476515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30063
BRD-K57732605	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98197
NMB	DepMap CRISPR Gene Dependency	1.0	2.25756
BRD-K59847773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.20451
BRD-K84391462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33565
GSE126621,GSE126920_1_v_0_dppa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
chr11_295527_T_C_b38	GTEx eQTL 2025	1.0	1.02602
GSE210101,GSE210114_0_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SREBF2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00432487
SREK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00825114
CSNK1A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00520314
MAGI1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00696021
MMACHC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01378
GSE213650_0_v_1_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
Familial hemophagocytic lymphohistiocytosis 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.086
CA9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00567692
CPED1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00623481
GSE192663_3_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE144231_2_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Osteogenesis imperfecta	ClinVar Gene-Phenotype Associations 2025	1.0	null
BRD-K85659077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.21802
GSE120612_7_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K66690073	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26453
BRD-K37387086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50977
GALNT2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00789809
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	68.6967
CLEC4D	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00803282
GSE234340_3_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TDG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00760093
TPD52L3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00513823
Arterial endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.692
P4HB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00519785
RFXANK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00726968
NB6	DepMap CRISPR Gene Dependency	1.0	9.10919
ADRB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00461009
GSE198165,GSE198166_9_v_4_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CXCL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00376081
GSE245134_2_v_3_atg5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.827
GSE148200_3_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Multilymphoid progenitor cell_Umbilical cord blood_Human	CellMarker Gene-Cell Type Associations	1.0	null
GSE160246_0_v_1_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151782_2_v_7_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE164874_5_v_14_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K94247332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13855
PMC11933697-41467_2025_58216_MOESM8_ESM.xlsx-SD6_ATF3_EV_NS1-SYMBOL_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K80381603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78471
BRD-K80232129	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27386
KCNH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00772952
NADK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00744615
ZNF281	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	207.911
GSE210101,GSE210114_0_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Montelukast	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.26
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.8753
NCIH650	DepMap CRISPR Gene Dependency	1.0	3.97017
CLCNKA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00562962
RMUGS	DepMap CRISPR Gene Dependency	1.0	2.88595
MEOX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00696034
GSE131660_2_v_0_piperlongumine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AIP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00575722
GSE135352_2_v_3_napabucasin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ATP23	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0073788
ASCL5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00710413
BRD-K06418332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02817
GSE226249_0_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GC-1 spg cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.829
GRK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00698682
MTOR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00517218
GSE160817_5_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Uterine disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.001
RSBN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00584028
GSE184399_0_v_3_cnot1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K77250455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.15075
JUN-27471255-CHONDROCYTES-MOUSE-RIB	ChEA Transcription Factor Targets 2022	1.0	null
PMC5651844-41467_2017_1173_MOESM5_ESM.xlsx-Down_genes_shY2-1-Supplementary_Data_1_Down_regulated_genes_in_ShY2_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
IL21	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00788927
CRCGN017_MCF10A.WT.HP_24H:N22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9604
CXXC5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00998923
CRCGN011_HEPG2_24H:F06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3422
SHTN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00846058
GSE191015_0_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K26552461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14066
MS4A5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00781525
UBE2L3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00564933
GSE190186,GSE190188_8_v_5_apoe_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE184210_0_v_3_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE144745_0_v_1_mettl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Delayed sleep phase syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.427
BRD-K23704908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00573
GRM5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00522564
BRD-K68853384	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76828
LY75	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00640392
NCIH23	DepMap CRISPR Gene Dependency	1.0	2.56978
SIAH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00387048
NFATC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00469525
GSE125011_0_v_2_cd83_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K47854067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01527
GSE164874_5_v_12_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.451
C6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00612184
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157F_vs_MSX1-Gene_name_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
GPM6B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00706733
HS578T	DepMap CRISPR Gene Dependency	1.0	2.00593
BRD-K48899005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51416
PRR5L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00987408
TM9SF4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00619611
GSE233679_12_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE140651,GSE140653_2_v_1_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE206516,GSE206518_6_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210580_3_v_2_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Anastrozole	DeepCoverMOA Drug Mechanisms of Action	1.0	0.33
Hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE234340_4_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K28720546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09639
RSC1A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00561599
SLC5A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00480653
BRD-K06356885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56237
GSE179880_10_v_3_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE184902_4_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MLLT11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00574381
GSE255432_7_v_3_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Female reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.001
ES5	DepMap CRISPR Gene Dependency	1.0	2.4792
MED12L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71867
ACKR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31968
TSPAN4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00552855
BRD-K77884956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67115
BRD-K00446585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09698
GSE239844_4_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TP53RK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00632333
BRD-K62193937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23484
PMC8986528-41586_2022_4598_MOESM6_ESM.xlsx-Fig_4f-NOL9_KD_downreg_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GNA15	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00419017
GSE191015_1_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE226091,GSE226092_0_v_1_sall1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Female reproductive organ benign neoplasm	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.001
BRD-K05392698	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04654
CRCGN015_MCF10A.WT.HP_24H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.37177
GSE114992,GSE114993_8_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CDIPT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00799221
BRD-K38519585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01062
GSE216273,GSE216292_0_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K39342915	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.10085
SLC6A13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00757751
BRD-K54364215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04897
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6043
GSE110524_2_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TUBG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39878
BRD-K79997957	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04966
IL2RA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00745288
GSE169205_0_v_5_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8907
HDAC8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00633367
TOE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45118
BCL2L14	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00465139
BLVRA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0060505
BRD-K90133009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00461
SORBS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54053
BRD-K90349877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10452
GSE158834_1_v_13_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE152937_12_v_7_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Astrocyte_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
GSE172295_0_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A_48H:H22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.43925
NME4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00742061
BRD-K20073772	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43814
PMC7793767-Table_2.docx-1-Downregulated_genes_in_the_pancreas_of_AA_vs_controls_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE110440_2_v_0_rad21_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FLNB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00774543
BRD-K76135327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15745
GSE206516,GSE206518_1_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PAWR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00679419
GSE118077_1_v_8_sprr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
FAM234B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42822
BRD-K64732418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2857
BRD-K36368568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26758
GSE145445,GSE145454_0_v_1_cop1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTPBP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00572887
GSE211126_1_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53909
ZNF263	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35709
GSE124375_13_v_0_chd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF682	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.8724
SNU16	DepMap CRISPR Gene Dependency	1.0	2.10838
BRD-K93956318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24234
APOE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00493434
CYP19A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00525594
PPP3R2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00812834
ALDH3A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00644146
FAAH2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00778469
PHLDA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00489565
BAG3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00514099
GSE143316_0_v_6_somatostatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
LIF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67035
BRD-A38066207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.73622
CRCGN011_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.8343
GSE188570,GSE188571_5_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
TLK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16258
SGPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19966
GSE228413_4_v_1_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K05220907	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06584
GSE120200,GSE127269_1_v_2_asxl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ARHGAP33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29028
L428	DepMap CRISPR Gene Dependency	1.0	2.8742
NFS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00368753
SERPINB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0061612
BRD-K66963616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31255
BRD-A57762296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09708
CD8B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00643309
MAPK11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00670959
GSE182680,GSE182683_7_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
SW626	DepMap CRISPR Gene Dependency	1.0	3.51753
SNU1544	DepMap CRISPR Gene Dependency	1.0	2.80524
PMC10248509-Data_Sheet_5.CSV--GSE66724_DE-Genes_AND_GSE41177_DE-Genes_NOT_Autophagy_NOT_GSE58294_DE-genes_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE151612_0_v_2_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K56884305	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36014
IGF2BP3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00815514
NCF4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00533589
RNPEP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00702388
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.5901
PMC7217064-IJC-146-3354-s004.xlsx-Table_S5-Supplementary_Table_S5_Genes_significantly_upregulated_in_OC2-transfected_AGS_cell_compared_to_control_ONECUT2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_Jurkat_LPS_vs_DC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.001
ADPRS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01929
GSE164874_5_v_0_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
STC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00508639
GUCY2C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00579423
BRD-K84401063	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82146
CRCGN011_HEPG2_24H:F11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12535
PMC11461876-42003_2024_6975_MOESM3_ESM.xlsx-Supplementary_Data_1-Supplementary_Data_1_Differentially_Expressed_Genes_HSE_THP1_Vs_THP1_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K87878529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0396
VPS35	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00475213
GSE202434,GSE202438_13_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE214212_3_v_1_chd6_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K95460104	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65344
RXFP4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00680484
GSE162739_2_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MS4A13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00586651
THY1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00890502
WDR6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00593363
CFI	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00610642
TRPC6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00347543
GSE171572_3_v_4_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
CD274	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00820981
CCDC141	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00678338
CRCGN016_MCF10A.WT.HP_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.97932
PRSS23	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00447211
KLF14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	122.113
BRD-K60531990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41943
BRD-K21759602	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31184
BRD-K40266835	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68753
GSE229468,GSE229471_2_v_3_znf587_human	RummaGEO Gene Perturbation Signatures	1.0	null
Intracranial aneurysm	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.827
GSE160304,GSE163392_2_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K59709341	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17475
NPC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00435668
GSE122215,GSE122217_0_v_4_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158834_12_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
C13orf42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02026
SEPTIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14261
BRD-K12107412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17911
GSE127790_9_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prdm14	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.1464
GSE218060_2_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PARP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0119
AGTR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00684443
BRD-K52218664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30681
F11R	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00690621
GSE58724_3_v_4_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
USP19	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00439068
GSE234340_3_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
INF2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0111123
KDM5B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00374834
GSE118077_4_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K39534157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18702
CFAP46	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00624735
GSE102505_1_v_2_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE74251_2_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE198165,GSE198166_8_v_4_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE168798_0_v_1_isg15_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10333092-aging-15-204811-s004.xlsx-Sheet1-Supplementary_Table_3_SP100_family_and_its_400_co-expressed_genes_SP100	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158632_2_v_5_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SYN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00674601
BRD-K85398599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37426
GSE190316,GSE190324_6_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE226285_3_v_0_nr0b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Uterine benign neoplasm	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.001
PPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52031
GSE226249_5_v_3_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE94849_6_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K95651150	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96316
GSE223893_11_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:L09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9344
496100645_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05287
JHUEM1	DepMap CRISPR Gene Dependency	1.0	3.04708
CIB4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00911357
PMC12368104-41698_2025_1085_MOESM2_ESM.xlsx-Table_S12-Supplementary_Table_12_DEG_of_Neu_05_IFIT1_and_Neu_04_STAT1_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE216043_10_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE220520_3_v_4_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K69238239	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98776
BRD-K00509345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36568
BRD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00968206
ZNF93	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	204.088
GSE201309_5_v_0_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12178829-mmc4.xlsx-Sheet_4-MEG3-KD_Up-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K14925361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31505
GSE245390_2_v_1_acss2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90888
PMC4823830-ncomms11171-s4.xlsx-high_in_shRNA_TCF1-GeneSymbol_HNF1A	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
GSE188382_4_v_0_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
APCS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0067967
GSE135350_3_v_5_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FGR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00515093
LTA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00540765
BRD-K59437706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12095
NAT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36425
GSE218060_1_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SYT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00779531
SLC25A15	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00577913
BRD-K17199106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.3463
BRD-K59250830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07154
GSE84148,GSE96938_0_v_1_nrros_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NOC3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01611
PBDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7422
BRD-K15433418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42578
oltipraz	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17305
PDGFRL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00796351
STK32A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00874221
GSE120216_3_v_0_cbfb_human	RummaGEO Gene Perturbation Signatures	1.0	null
IDI1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.009605
BRD-K00586442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47403
SYT4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00557461
F5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00661812
ACSM5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00880906
MILR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00693964
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2427
BRD-K37486644	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2791
JAML	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00725202
GSE200839,GSE233826_3_v_0_tnrc18_human	RummaGEO Gene Perturbation Signatures	1.0	null
chr11_295343_G_A_b38	GTEx eQTL 2025	1.0	1.49793
GSE158834_10_v_8_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE164874_5_v_8_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE239844_7_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MYOM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00538417
GSE158456_1_v_3_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
STH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00575019
BRD-K55508908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47652
BE2M17	DepMap CRISPR Gene Dependency	1.0	2.80918
GSE77108_8_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE226249_0_v_3_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCM-460 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.663
GSE225083_0_v_1_kras_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K86111620	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14957
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.892
BEST1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00781859
GLRX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35332
RASGEF1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00879623
BRD-K98541397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70057
BRD-K42150052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34463
ACTR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00621116
ZNF257	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.6594
BRD-K32176914	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58389
COX4I1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00483016
Gastrointestinal tract	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE98831_1_v_0_brca1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PLXDC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00582876
Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.5848
GSE101239_5_v_0_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K05253426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.20292
TMEM117	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00789118
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	62.3016
DHCR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22981
HRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00828
CLMP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00646362
CTCF-33576154-HUMAN-HILARLN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
GSE206226_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.28
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.0038
PLEKHM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00542815
RAF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00660727
S1PR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0100841
BRD-K86746660	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.70416
496100348_TCx_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.05996
RELA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2222
Gastric epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.652
TRIP13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60481
BRD-K76400756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83427
BRD-K18768055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18147
BRD-K15201964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.28433
METTL23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01257
BRD-K39985369	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26614
GSE135030_11_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE226316_4_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216043_7_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	144.066
Autoimmune thyroiditis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.004
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.004
LYVE1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0105835
RPS6KA5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00517949
BRD-K32943057	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78191
GSE124471,GSE124488_1_v_3_lats1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE80098,GSE80366_0_v_8_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
KCNK7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00530638
PMC12848082-41598_2025_33574_MOESM3_ESM.xlsx-MR-PRESSO_eQTL-Unnamed_1_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
LOUNH91	DepMap CRISPR Gene Dependency	1.0	2.47691
TRIM29	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00559155
PMC8872993-41380_2021_1274_MOESM4_ESM.xlsx-Table_S6-Supplementary_Table_S6_Differentially-Expressed_Genes_after_T-3_KD_in_hiPSC-derived_Astrocytes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_MCF10A_48H:F10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17804
GSE242290_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OVCA420	DepMap CRISPR Gene Dependency	1.0	3.71725
GSE217071_1_v_2_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:E16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.03594
PMC5195898-NIHMS825571-supplement-3.xlsx-Sheet1-H1975_M1_vs_H1975_M1_CIC_reconstitution_Differential_gene_expression_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6357748-aau9223_Table_S1.xlsx-CD4_T_-_LPS-Unnamed_0_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CD81	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00675846
IFIH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.006813
GSE217201_1_v_0_asap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10199266-mmc2.xlsx-RUNX1-DEGs-Unnamed_1_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K35780971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34998
BRD-K70870890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04231
BRD-K87290989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11475
PMC7064337-elife-51373-supp1.xlsx-EZH2_targets_shPHF19-List_of_2084_genes_marked_by_EZH2_ChIPseq_after_PHF19_KD_shPHF19_AR	Rummagene Transcription Factor Associations 2026	1.0	null
FAM89A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00551405
BRD-K93737936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7098
UNCX	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00627784
BRD-K27616520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84615
GSE132694,GSE132717_0_v_2_meis1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KBTBD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00618738
PTGES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23642
TRPC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00981517
CHD9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00720864
CRCGN012_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2399
PMC10528072-NIHMS1928302-supplement-5.xlsx-ASCL1-target_genes-ABAT_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
IMR32	DepMap CRISPR Gene Dependency	1.0	2.1761
SNU216	DepMap CRISPR Gene Dependency	1.0	2.32098
PMC6604319-13072_2019_278_MOESM3_ESM.xlsx-CEM_ect_TET2_DEGs_DMRs_hDMRs-CCRF-CEM_EV_vs_ectopic_TET2_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
Mood disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.985
LTB4R2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00793683
ANKRD55	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00461187
GSE181003_1_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
TMEM177	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52177
DIDO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0082405
GSE201309_1_v_0_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HDAC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08054
SW837	DepMap CRISPR Gene Dependency	1.0	2.72162
CAMSAP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00505259
GSE184892_4_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE210682_2_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Central nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.827
Helper T-lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.799
BTF3P11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00714919
CAMKK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00821864
BRD-K42713448	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26788
GSE226091,GSE226092_0_v_4_sall1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K04195898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16243
CLEC17A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00953733
BRD-K36055854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31577
BRD-K39813155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75515
CEACAM8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00388944
GSE213228_1_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE68925_1_v_0_fasudil_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K27653895	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39446
EGR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.4761
TNFRSF10B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00619444
BRD-K19106745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70718
BRD-K03070790	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18706
GSE169356_2_v_3_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K99521908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0801
MYH9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45639
DNAJC5G	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00713549
GSE191174_0_v_1_ccdc92_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE232786_1_v_0_otud1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GEMIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23903
GSE122711_2_v_3_mpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Uterine fibroid	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.001
BRD-K32862383	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09317
PMC6187090-mmc1.xlsx-TP53_positive-Symbol_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GSE124097_3_v_0_trem2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.7362
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.2605
RAB3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45162
IL1RAPL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00622348
PYHIN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00593434
CCNT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00520298
GSE111385_0_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ADAM17	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0089255
BRD-A07861932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79542
GSE184902_3_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC5651844-41467_2017_1173_MOESM4_ESM.xlsx-sheet_1-Supplementary_Data_1_Down_regulated_genes_in_YEATS2_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
OSCAR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00671356
SORL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00666125
CDH6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00499061
NEIL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00850641
BRD-K02691653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24934
GSE96641_1_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K00933790	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89567
TFAP2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	195.23
PBXIP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00496547
GSE79291_1_v_2_streptozotocin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RBFOX3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00769231
TCN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00508004
BRD-K45498945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16683
GSE169356_2_v_1_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NUBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00056
ZNF549	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.3996
HLCS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00741467
OGFOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53453
DUSP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00518571
EIF3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28209
EXTL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00979029
CRCGN015_HEPG2_48H:A14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.07332
BRD-K88498468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27859
GSE157960_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CYP2A6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00722558
PRKN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0052212
TAFAZZIN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00691589
GSE176008_4_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216043_7_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SPATC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0049142
BRD-K58614056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27986
BRD-K39571490	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9922
SPINK5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00766618
GSE85880,GSE85881_0_v_1_tretinoin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CD160	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00740662
GSE209582_1_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE160817_0_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:F24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23717
BRD-K43834805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83598
GSE184902_4_v_1_adipor1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:L23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00445
GSE185519_4_v_7_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAPKAPK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00332786
TCF12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0067723
NB17	DepMap CRISPR Gene Dependency	1.0	5.37427
GSE131425_2_v_3_arg2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K19567079	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55556
GSE131161_2_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K86978618	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24144
GSE128730_3_v_1_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
F36P	DepMap CRISPR Gene Dependency	1.0	4.42368
EPN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00379583
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.7509
BRD-K31883758	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48004
GSE226115,GSE226116_2_v_0_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.3608
ADAM12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0114759
BRD-K22715231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2127
KCNN4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00400927
GSE125782_3_v_2_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TIRAP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00596125
GSE245778_1_v_0_runx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
NUF2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00510898
PMC12917211-Table1.xlsx-Table_S13-Table_S13_Gene-level_perturbation_statistics_from_the_virtual_KLF5_knockout_model_in_malignant_ductal_cells_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K13526697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62205
CRCGN016_MCF10A.TP53.M_24H:C05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.45551
BRD-K66511507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5361
GSE114992,GSE114993_7_v_10_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216043_7_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K81515704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55778
GSE164757,GSE164759_1_v_3_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K74506898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01246
BOD1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35032
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_EC109_KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE138019_3_v_2_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IL18	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00575923
GSE154767_2_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SLC22A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00881617
CRCGN008_HEPG2_24H:I05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0045
GSE86507,GSE86509_7_v_9_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LC1SQ	DepMap CRISPR Gene Dependency	1.0	3.03144
CRCGN017_MCF10A.WT.HP_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4498
CLDN11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00542206
IFNB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00649993
BRD-K02602127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06523
TREML4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00601161
BRD-K58883090	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.49065
NMRK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0063941
ENDOU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69422
FAM204A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40612
BRD-K58310485	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.654
BRD-K34851865	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54156
CRCGN008_HEPG2_24H:P02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5942
Fenoldopam	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.33
BRD-K89110518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43203
GSE242083,GSE242098_3_v_1_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LCP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00417137
ATF4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00490024
TNFSF4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00773619
BRD-K21986392	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06748
LDB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19731
D283MED	DepMap CRISPR Gene Dependency	1.0	2.07985
BRD-K91696235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05206
BRD-A70931301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53563
BRD-K75497233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77334
GSE226983_1_v_0_ddx5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KIRREL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00583109
GSE181003_1_v_2_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
KGN cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.032
GSE127790_11_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K26214610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30992
CDKL3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00672929
Taurine dioxygenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.536
ZBTB24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.6691
TFAP2E	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.6791
HCRTR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00581282
BRD-K34524418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68315
BRD-K09878843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07084
ENTR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00513042
GSE152441,GSE152442_1_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K41089262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.061
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Benethamine	DeepCoverMOA Drug Mechanisms of Action	1.0	0.23
TESK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00752347
XCL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0074443
GSE101527_3_v_2_smad4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NEK10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0069803
KCNE2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00564703
Ixazomib_A-427	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00660493
ZNF792	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.087
BRDT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00839648
TMEM265	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68725
GSE199255,GSE199356_3_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216273,GSE216292_14_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE169152_3_v_4_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ANAPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45958
ITGA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00704846
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	51.0331
BRD-K34274486	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.28652
GSE129772_2_v_3_runx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PPP4R2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00703523
PMC6172843-13059_2018_1523_MOESM6_ESM.xls-Sheet1-Table_S5_mRNAs_variation_abundance_1_5-fold_in_YBX1-knockdown_BGC-823_cells_YBX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K18783332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12835
GSE190316,GSE190324_10_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
BIRC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08755
BRD-K96745500	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39541
SP5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.6275
GSE135350_3_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OBSCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09505
IQSEC3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0071009
MAF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00993619
DCTN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9285
GSE157960_0_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE226249_0_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6347712-pnas.1812449116.sd06.xlsx-iPSC_IRF7_48h_rest_RNAExpress-Gene_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
SPEG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00559332
BRD-K69840402	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.15949
BRD-K42400613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01181
496100527_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.16748
BRD-K61909412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24639
TNFSF15	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00517988
KIAA0930	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03981
NDUFB5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00657445
SPIRE2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00628574
BRD-K68162101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20422
GSE183041_1_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNX17	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00429306
GSE157036,GSE166411_3_v_1_halofuginone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE140651,GSE140653_2_v_6_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AASS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00569842
ACVRL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00728008
496100375_FWM_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.17559
RUNX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09614
CNTN3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00447826
TNNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6236
BRD-K14436020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05355
Artery disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.827
PMC12205070-41467_2025_61222_MOESM5_ESM.xlsx-DE_markers_TAL1_scenic_reductio-gene_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.1461
MAP3K19	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00697905
GSE158632_2_v_4_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE213228_2_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K03479638	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43329
BRD-K97721960	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07502
GSE193402_0_v_3_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K50367303	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26405
BRD-K98224452	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33682
PMC4954754-elife-15550-fig3-figsupp1-data1.xlsx-HSF1_Genes-Unnamed_18_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE223008_7_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE95688_7_v_5_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.3355
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0156
STAC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00779494
BRD-K07013504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05902
GSE211128_3_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE103068_5_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ALOX15	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00365008
POM121L2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00573156
LY2801653	DeepCoverMOA Drug Mechanisms of Action	1.0	0.55
BRD-K64474460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49743
Bardet-Biedl syndrome 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.206
NDUFA4L2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00609531
CREG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00401631
PMC4954754-elife-15550-fig3-figsupp1-data1.xlsx-HSF1_Genes-Unnamed_12_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
GCSH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00542154
GSE128634,GSE128636_1_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
OAZ2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00576266
GSE162892_4_v_5_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
Vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.827
CHRNG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00740462
GSE58724_1_v_4_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HBA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00522931
Prdm15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.6585
OC316	DepMap CRISPR Gene Dependency	1.0	2.50405
BRD-K40809590	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90574
PMC12549544-mmc2.xlsx-AA_D1_VS_D7-Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
ARHGEF25	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00703937
KCND1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00461158
496100316_TCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.25238
GTEx Esophagus 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	1.0	6.89679
Duodenum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE128730_4_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE171837_3_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ACTA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0056298
CD300LD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0078866
REG1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00503611
SMARCA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00549156
BRD-K37592272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02282
BRD-K79551673	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17813
APOH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00513849
BTBD8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.007042
CSAD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00453117
GJD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00769416
GSE240258_0_v_1_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE126621,GSE126920_1_v_3_dppa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KDM3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00457538
FCRL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00447705
PPIP5K1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00429703
BRD-K64536135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2263
CACNG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00645742
BACE2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00598232
KLF15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	134.124
GSE237040_4_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K27111500	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.37563
GSE211177,GSE211178_4_v_1_ets1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216043_7_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SLC19A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00641856
CD47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24235
GSE199660_1_v_0_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE163862_0_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K36798110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83613
GSE216043_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LIG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44711
GSE198165,GSE198166_0_v_4_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TRRAP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00650688
BRD-K02053819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04745
SLC6A12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00709609
BRD-K01762107	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10034
IL1RL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00515607
HMCN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00606083
Digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE87412,GSE92423_0_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K92520489	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41719
BRD-K10635555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81972
HEY1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4346
BRD-K40887375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25012
GLIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.4271
GSE152432_6_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SIGLEC10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0102851
BRD-K63779242	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00479
GSE115364_0_v_1_idh3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SLFN12L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0104115
GSE154767_4_v_3_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148066,GSE157787_8_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.7968
MPEG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00667879
GSE127790_4_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K30795375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78429
GSE169152_5_v_4_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
venetoclax_A-427	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.011488
BRD-K09261031	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32717
BRD-K39037393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7136
GSE237040_6_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FC-20-EQ58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.224224
SHARPIN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00416003
GSE240386,GSE242143_1_v_4_morc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K91191855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20447
BLOC1S6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0053964
SUDHL10	DepMap CRISPR Gene Dependency	1.0	2.29087
CERKL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00835233
BRD-K17675814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20805
GSE140607_5_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8314029-12931_2021_1797_MOESM5_ESM.xlsx-DE_genes_in_ACDMPV-Gene_name_FOXF1	Rummagene Transcription Factor Associations 2026	1.0	null
LSM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68111
GSE224096_3_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K64001802	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00959
GSE155695,GSE155696_1_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE221742,GSE221743_1_v_0_sipa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ANKRD27	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00505292
OGDH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00587772
SMARCAL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00450179
BRD-K62541003	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22221
SNAI2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00862409
C75	DepMap CRISPR Gene Dependency	1.0	3.70524
BRD-K57226184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05322
GSE151612_0_v_7_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GCLM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08428
GSE213588_9_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE48812_7_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
KCNB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00760831
GSE209911_0_v_1_ncstn_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE208350_4_v_1_fgfr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.0354
PMC5095001-oncotarget-07-36293-s002.xlsx-Table_S2-Table_S2_MYCN-correlated_genes_and_their_correlations_with_other_transcription_factors_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12784616-12711_2025_1028_MOESM2_ESM.xlsx-TableS8-Table_S8_Summary_of_significant_MR_associations_in_liver_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
FST	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00895528
GSE223008_7_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169152_3_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE114232_8_v_11_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
UGT1A9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00607586
BRD-K84836394	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13221
BRD-K54143708	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11136
BRD-K06250424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12681
HLA-DRB5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00775148
ZNF280B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00583922
TSPOAP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00699994
GSE114013,GSE114014_1_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K14812927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56183
EGR4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.5059
GSE198165,GSE198166_6_v_11_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE217115_3_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE111247_11_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NUCKS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00589392
GSE250534_4_v_1_cabergoline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K04143388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11427
GSE126776_2_v_1_pelp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K90004516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77413
COGN305	DepMap CRISPR Gene Dependency	1.0	3.62284
TTBK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00776209
GSE186440,GSE186443_4_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19429
SEMA4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09545
Tracheal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.962
RUNX2-24655370-MC3T3E1-MOUSE-BONE	ChEA Transcription Factor Targets 2022	1.0	null
PMC6319725-pone.0204197.s006.xlsx-Table_S2-S2_TABLE_-_Operon_Expression_and_SOM_clustering_data_for_Gene_Set_identified_by_ANOVA_p_0_005_1005_genes_FDR_8_8_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE48812_3_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE184902_4_v_1_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MKRN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15339
RBM47	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00800789
GSE207914_3_v_6_nudt7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SMARCA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06263
GSE202434,GSE202438_10_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TXNRD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00704439
PMC11961801-12672_2025_2262_MOESM2_ESM.xlsx-Sheet_1-WGCNA_AND_DEGs_NOT_CSGs_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
RAB11FIP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0077815
CARD11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0092243
GSE153354_0_v_1_tcf19_human	RummaGEO Gene Perturbation Signatures	1.0	null
TOP1MT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00783376
GSE123502,GSE123504_1_v_0_chd4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RERFGC1B	DepMap CRISPR Gene Dependency	1.0	6.66239
EFNA3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00601836
BRD-K43431234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.33721
GSE158431_2_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K31325635	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26965
BRD-A27693633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84924
MYBPHL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00504381
CILP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00658012
GSE211983_0_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SMAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7312
CILK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00884386
CRCGN008_HEPG2_24H:L14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03935
ERAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18819
BRD-K50511447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02372
SLC26A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00382677
BRD-K25127909	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43789
NME7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0057657
RAD51	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00652351
CRCGN013_HEPG2_24H:J05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04749
GSE213650_3_v_1_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
TRIB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00677846
DGKE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0087955
KAT5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0115215
CBY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03837
BRD-K19702946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14541
GSE164483_2_v_0_venetoclax_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K73899967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77991
GSE206729_3_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE223893_1_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.4294
GSE158431_2_v_0_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K54836449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79932
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.4137
BRD-K46171140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35723
BRD-K13271778	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3408
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.827
SOGA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84034
BCAP31	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0081978
SP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.3476
BRD-K62692910	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56332
GSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80369
CMTM7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00638769
PLCB3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00381237
GSE114992,GSE114993_7_v_3_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K22701871	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0121
GSE200352_1_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE201309_5_v_7_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE213228_1_v_3_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
aklomide	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48316
CETP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0098446
GSE135686_2_v_3_etomoxir_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1888
AAMP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00794275
GSE184892_0_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE193993_0_v_7_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GRIN2D	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00610221
BRD-K74855272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03309
BRD-K62150807	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63277
GSE151090_2_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K75980238	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06782
GSE158834_12_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE201309_5_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
TMEM258	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58766
Postmenopausal osteoporosis	ClinVar Gene-Phenotype Associations 2025	1.0	null
GSE172295_1_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OV7	DepMap CRISPR Gene Dependency	1.0	3.35766
CRCGN017_MCF10A.WT.HP_24H:N17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.0088
CFD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00616152
BRD-K79562803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01397
VPREB3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00702624
TRIM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15887
POLR3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07504
BRD-K31300534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30411
GSE242290_3_v_2_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K42797038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99517
BICR10	DepMap CRISPR Gene Dependency	1.0	3.079
BCAT2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0132354
GSE245134_0_v_1_atg5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216352,GSE216354_1_v_0_keap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
UNC119	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00645167
GSE152937_12_v_1_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OR2L13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00780783
CXCL5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00863365
PMC5670203-41467_2017_1251_MOESM5_ESM.xlsx-differential_expressed_BCL6_tar-gene_id_BCL6	Rummagene Transcription Factor Associations 2026	1.0	null
DSG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98829
GPI	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00425379
GSE226249_0_v_4_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TTC7A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00453807
BRD-K17718789	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.48055
SPRED2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00440418
Tonsil	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CRCGN011_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.604
ASMT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00497993
GSE173810_0_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Beckwith-Wiedemann syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.138
Ejaculatory duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.616
BRD-K71486446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26312
Autoimmune disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.004
CASP9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00573969
JAK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00743035
H2BC12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00522883
HIF3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00641516
BRD-K64221857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21971
GSE149359_2_v_0_asap2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TARBP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00804902
BRD-K54604127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47264
GSE158834_1_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:K19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.69196
TSPAN13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00755878
BRD-K72549552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.21098
ASPHD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00751542
BRD-K13572796	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.33647
RHOBTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35243
GSE152441,GSE152442_1_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
T-lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.838
COX6B1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00809867
GSE213588_10_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K72519622	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19464
BRD-K98061543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.30926
BRD-K79318338	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.14843
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-8_DEGs_RUNX1-OE_vs_control-Gene_Symbol_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
CD151	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0102644
GSE111247_2_v_8_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.3286
USP42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07925
BRD-K06408981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18832
CAMA1	DepMap CRISPR Gene Dependency	1.0	2.87778
GSE165307_2_v_0_gfi1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157904_3_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PHGDH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0047025
GPR171	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00963177
REST	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0048384
BRD-K93316985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01566
GSE118077_7_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Intracranial arterial disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.827
PMC10985171-Table_1.xlsx-Table_S3-Table_S3_IPF_related_genes_screened_by_MR_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K54362440	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53194
MAP3K6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00496195
BRD-K38350115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35969
STS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00622417
BRD-K86109840	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08859
ELK4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00714418
RAC3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00544313
GSE120612_7_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RBPJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73445
GSE189609_1_v_2_hax1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182680,GSE182683_10_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
ZNF213	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	127.607
UCHL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00599263
light-harvesting complex, core complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.429
LYSMD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00850327
GSTA5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0080845
PMC10319804-41467_2023_38747_MOESM9_ESM.xlsx-KHSRP_KD_genes_up-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0037
GRM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00665904
WAS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00466691
GSE200982_0_v_2_plac8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CD101	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0059374
GSE122711_1_v_3_mpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K82538319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23456
BRD-K20203758	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.26147
GSE124471,GSE124488_2_v_3_lats1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE255432_7_v_2_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE233049_1_v_3_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cerebral arterial disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.827
BCL7C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00920697
BRD-K82446079	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04704
PMC5303304-13073_2017_407_MOESM5_ESM.xlsx-mycn-sy5y-se_single_24DMSO_vs_4-Table_S4_Genes_differentially_expressed_by_48h_Dox_MYCN_overexpression_treatment_DE_comparison_with_SY5Y-MYCN_control_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
GSE200839,GSE233826_3_v_6_tnrc18_human	RummaGEO Gene Perturbation Signatures	1.0	null
RBFOX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00561656
496100478_HIP_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.58141
LRRN3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00570758
GSE97352_3_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51981
HINFP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.2177
TRIM22	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00504932
ADAMDEC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00553616
PMC11214527-mmc5.xlsx-POU5F1-gene_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
PRKAR1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00940708
TEAD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00617837
ANKRD50	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00795322
GSE114992,GSE114993_4_v_6_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE171177,GSE171181_1_v_0_e7107_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GABPB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00652869
GSE135030_8_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE179002_4_v_7_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EDEM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00610238
PMC9882185-media-2.xlsx-All_B2-AR_targets-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9714459-DataSheet3.xlsx-Supplement_3A-1166_common_elements_in_MSC_and_Fibroblasts_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
PCGF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21381
MAGI2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0090963
PDHA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00705965
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	60.3
BRD-K69668687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10781
SLC22A18	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00677184
CRCGN008_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6528
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.52397
BRD-K74540252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06894
BRD-K89264608	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06794
PARPBP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00631247
ACAD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03574
HLA-DMA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.005281
POU2AF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00596232
BRD-K97373334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09863
BRD-K72073851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66918
SP9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.4188
SLA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00987988
GSE193993_5_v_3_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6858560-NIHMS1538530-supplement-Supplementary_Tables.xlsx-Supplementary_Table_21-Supplementary_Table_21_Aberrant_Splicing_Events_in_TET2_SRSF2_co-mutated_AML_Patients_from_the_TCGA_cohort_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
FBXW7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00734423
TAOK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00661491
CRCGN015_HEPG2_48H:E14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14561
BRD-K48255349	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22096
BRD-A08191729	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2085
CEP170	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00826002
GSE158834_1_v_4_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HDAC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00721281
CRCGN016_MCF10A.WT.HP_24H:E20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.27233
SGK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00604295
TNFSF18	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00521158
AKR1A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00837333
LCT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00640231
BTNL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0106384
BRD-K87081268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06444
LMCD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00547519
MAPK8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00568229
GSE218580_1_v_5_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MCFD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00518144
GSE58724_1_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TEAD4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00635927
GSE182179_0_v_1_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
DMD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00900161
GSE102505_6_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HSPA1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00720939
BRD-K07895476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43276
DEPDC5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00799398
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.1815
ZIC5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.6836
BRD-K09560946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64765
GSE235550_2_v_0_hspa9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
WIPF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0102867
SLC41A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00547098
GSE235587_2_v_0_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	1.0	null
RAB31	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00750028
CHPF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.005929
LRIT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00779994
GSTM4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00567614
BRD-K70843862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.52694
PMC12068594-pgen.1011693.s007.xlsx-MCR_vs_MCW-gene_id_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
PTGR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00607682
BRD-K64860662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50799
CDCA7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00910085
BRD-K80443236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1891
GSE148066,GSE157787_8_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GRIN2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0110875
GSE200388_0_v_1_gemin5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158834_0_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K57821544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44504
GSE158834_10_v_6_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE184892_7_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11063202-41420_2024_1940_MOESM2_ESM.xlsx-THP1-EP300_KOvsNontarget-gene_id_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
GGT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20646
PMC11732233-mmc1.pdf-420-DUX4L24_DBET_LOC10029162_6_DUX4_LOC1_00288289_LOC_100287823_LO_C100133400_D_UX4L2_DUX4L3_DUX4L5_DUX_4L6_DUX4L7_LOC652301_DU_X4L4_DUX4L8_DUX3_DUX4L1_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K12399715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09776
BRD-K29903367	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32812
DTX3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0050853
GSE195663_7_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE106661,GSE106665_0_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE101239_4_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE166944_0_v_2_eif4b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE173873_10_v_6_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SPHK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00565119
BRD-K41643612	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60058
BRD-K76578941	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00665
COLO205	DepMap CRISPR Gene Dependency	1.0	2.15877
PRDM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00460261
BRD-A19962819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31343