association	dataset	threshold value	standardized value
GSE205163,GSE205164_2_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00195
BRD-K61796560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24244
GSE154074_5_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE211286_4_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K34808207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.41202
BRD-K85996308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8551
CRCGN014_HEPG2_24H:I24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.70411
BRD-K67096761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03096
PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_14_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE200982_0_v_2_plac8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE223334_1_v_0_bcl11b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE199255,GSE199356_3_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146982_3_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE57871_11_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
FZD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60268
CRCGN013_HEPG2_24H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.34601
BRD-K42457027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.3728
GSE130246_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN012_HEPG2_24H:G07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.16292
CRCGN011_HEPG2_24H:I20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00625
BRD-K97886487	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01218
RIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02875
GSE119564_2_v_0_zfp217_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.07005
GSE240027,GSE240030_1_v_2_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE139016_3_v_2_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K42475945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.002
BRD-K24748087	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10494
BRD-K17136501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18967
BRD-K64296795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35186
CRCGN014_HEPG2_24H:D13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.09995
GSE122215,GSE122217_5_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K18074484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06297
BRD-K97805186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.26177
CRCGN015_MCF10A_48H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6677
BRD-K92749855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28595
GSE200352_5_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	10.0
BRD-K62892366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80503
CRCGN016_MCF10A.TP53.M_24H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18328
GSE152432_6_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.8704
PMC10915192-ab-23-0304-Supplementary-Table-S5.pdf-109-HOXC6_HOXC6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE244072_10_v_9_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76748
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K22718400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30481
6555_POLR3A_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.67435
GSE235550_2_v_0_hspa9_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.23683
TMPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52778
BMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62262
7910_SIGMAR1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.799251
CRCGN014_HEPG2_24H:F21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9259
PTK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13371
BRD-K27229533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27008
GSE165548_2_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K10087503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18677
BRD-K97440159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19306
BRD-K53552465	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57937
CRCGN016_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.30066
CRCGN014_HEPG2_24H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.45797
496100307_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.45489
CRCGN016_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.40844
PMC11187533-f1000research-12-166562.nxml-Table_4-GSC_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
6625_PPIE_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.66647
BRD-K61973443	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33276
GSE119564_1_v_0_zfp217_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE129389_0_v_4_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.WT.HP_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.27013
BRD-K20157822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.51541
SEC62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06079
GSE110178_4_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K50498614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.30132
BRD-K11804865	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09932
CRCGN008_HEPG2_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11065
GSE197555_0_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4909989-ncomms11840-s2.xlsx-down-regulate-TEAD4-FL_YAP_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142210_2_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11329632-41419_2024_6969_MOESM3_ESM.pdf-97-ZBTB45_ZBTB45	Rummagene Transcription Factor Associations 2026	1.0	null
GSE249098_1_v_0_mthfd1l_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE110178_5_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K24387453	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13074
RCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05698
GSE132759_4_v_2_fgfr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE195559_0_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:O14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24965
GSE169356_0_v_5_ivermectin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN013_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.80333
GSE180800,GSE180801_0_v_5_tex10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE139016_0_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE111102,GSE111105_1_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE157594_6_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RAD51D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09114
K562_Enzastaurin_1µM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0157833
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.8413
BRD-K21584435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43572
GSE136742,GSE136744_2_v_3_setd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K61185334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24708
BRD-K23960050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.95096
BRD-K16605233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4559
BRD-K92613860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71236
BRD-K88720906	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55726
GSE226584,GSE226589_1_v_0_ezh2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
3291_GATA1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.517784
CRCGN016_MCF10A.TP53.M_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.77323
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.5328
GSE185519_3_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE215351,GSE215794_2_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135352_0_v_1_napabucasin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE125157_1_v_0_piceatannol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PSMB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23447
CRCGN013_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.59999
BRD-K91239327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11246
HES2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1588
MMP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30811
GSE190235_3_v_2_foxo3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.WT.HP_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.03237
496100555_TCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.92814
GSE95386_0_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.28755
GSE128240_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K12492021	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07986
GSE183271_1_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE195663_7_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nuclear splicing speckle	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
BRD-K83045795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06297
GSE186223,GSE186224_6_v_3_hmces_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
3503_GPN2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.50699
GSE219195_4_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ANKRD40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41409
BRD-K60068268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05162
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.339
496100322_FWM_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.66843
BRD-K94441949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53285
BRD-K18621941	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01592
GSE102467_1_v_2_pazopanib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A_48H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03611
BRD-K90644597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.29022
GSE111061_1_v_0_tofacitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:B17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1008
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0227
496100559_FWM_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.17178
BRD-K90999585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21901
GSE217982,GSE217983_2_v_3_hgfac_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE157592_1_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158715_2_v_4_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CEP350	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03501
BRD-K15943105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.65481
POLA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0368
GSE178255_5_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6963
GSE195663_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE199255,GSE199356_4_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151782_2_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K31874013	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97487
GSE162739_8_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE114883_1_v_5_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
RAB11FIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36679
GSE147876,GSE147877_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K68160857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53906
CRCGN014_HEPG2_3H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.6509
BRD-K82967678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68362
CRCGN013_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.09535
CRCGN015_MCF10A_48H:H22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.85226
GSE235390_4_v_0_lurbinectedin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216043_11_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K77041516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48698
BRD-K52047843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.32627
GSE207301,GSE207303_1_v_3_tp53bp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
7000_R3HDM4_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.510114
BRD-K70923850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56971
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9574
CRCGN014_HEPG2_24H:F22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.46767
GSE198165,GSE198166_0_v_1_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE112761,GSE112767_2_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.66795
BRD-K56957303	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14989
GSE138019_4_v_6_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AASS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08974
RAB11FIP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62512
PTF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0151
BRD-K69505608	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51274
BRD-K39961819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16707
GSE57871_1_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K33767317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.43463
LAPTM4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82374
CRCGN016_MCF10A.TP53.M_24H:E17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25074
VAT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10414
PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_EC_PSc_vs_NB_2D_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K56332068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32985
WRAP73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07248
synaptic vesicle membrane	GO Cellular Component Annotations 2025	1.0	null
ELAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03515
GSE164874_5_v_10_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE76771_1_v_3_atf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K98938484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11357
MRPL36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07678
GSE219274,GSE219276_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE125014_6_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6718408-41467_2019_11884_MOESM6_ESM.xlsx-TAD_genes_ST-EPN-RELA-Unnamed_4_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K30288714	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63057
BRD-K65831955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26975
K562_Baricitinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0167555
CRCGN016_MCF10A.TP53.M_24H:F11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18769
CRCGN008_HEPG2_24H:G24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.26355
3948_HSD17B10_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.618914
CRCGN017_MCF10A.TP53.M_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.36725
BRD-K25236390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00261
K562_MLN8054_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0170824
GSE114232_10_v_11_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211286_4_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7286
EIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88651
BRD-K83752863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14112
GSE199255,GSE199356_6_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE226316_3_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC3610249-1471-2164-14-184-S4.xls-miR-331-3p_targets-NR2E3_NR2E3	Rummagene Transcription Factor Associations 2026	1.0	null
ALG11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0804
BRD-K61934967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88172
CRCGN008_HEPG2_24H:E21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1824
CRCGN008_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.51065
BRD-K53931904	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67061
CRCGN014_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.298
NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.3021
BRD-K36465335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67746
GSE125014_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K69918256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90625
GSE122101,GSE122103_3_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.9445
ZBED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24224
GSE190384,GSE190386_0_v_8_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7617265-EMS137094-supplement-Supplementary_Tables.xlsx-ST18-gene_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
GSE146982_4_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K28510065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30133
PMC6996923-elife-46981-supp4.xlsx-KO_Up_Only_Vs_OCT4-Column_ID_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE217873_1_v_0_nusap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE188382_2_v_1_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.2914
GSE199255,GSE199356_0_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K65438558	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04375
DDX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05042
CRCGN015_MCF10A_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.9481
BRD-K86102179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.22493
GSE151612_4_v_7_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K16468319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01953
BRD-K95860374	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71041
CRCGN016_MCF10A.TP53.M_24H:P16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.61403
BRD-K27287379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34574
GSE169155_3_v_2_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE48812_0_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100407_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.47608
CRCGN016_MCF10A.TP53.M_24H:P18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.62345
BRD-K26361872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.47034
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.39572
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.8219
BRD-K42879623	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44846
canthaxanthin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14806
GSE112765,GSE112767_1_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K13038935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36937
KLF13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3766
CRCGN012_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.59742
EIF2B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66569
BRD-K01995700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69126
GSE168458_1_v_3_disulfiram_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K30895360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29489
BRD-K48777375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29491
BRD-K92712225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03223
BRD-K71216961	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12792
BRD-K64222382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94405
GSE146982_3_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE76771_2_v_3_atf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100340_TCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.25866
BRD-K97576000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78556
PMC3371315-NIHMS350140-supplement-9.xls-MCF7-T47D-SK-453_Up_MCF7-T47D_x-Supplementary_Table_2_ER-positive_FOXA1_signature_Genes_increased_only_in_MCF7_and_T47D_cells_with_knockdown_of_FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K73025859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72415
GSE234043_0_v_1_abcb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
DYNC1I2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74363
BRD-K67874412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2884
GSE228413_4_v_3_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_WHI-P154_1µM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0150195
BRD-K02240568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25962
4959_MED9_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.67173
BRD-K17078647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61725
BRD-K11013450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57229
GSE192689_0_v_1_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6855629-pone.0225186.s009.xlsx-Sheet1-DEGs_downregulated_in_HEK293_MEIS1_KO_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE195568_1_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
protein transport	GO Biological Process Annotations 2025	1.0	null
BRD-K89260735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53174
No annotation - 30	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
GSE102675_2_v_1_atf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Ascl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.1904
496100355_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.20035
GSE179693,GSE179694_4_v_2_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE142210_9_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2763
BRD-K08185175	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1848
GSE196699_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K11545984	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34299
CRCGN015_MCF10A_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5543
GSE158834_0_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K54362440	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44909
GSE158595_0_v_1_e4f1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE173232_1_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN010_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3593
GSE157594_5_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Npas4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.9625
BRD-K44684577	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00255
GSE165122_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3M_Peaks_YAP1MAMLD1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE179974_3_v_4_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K44402256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67783
GSE173578_1_v_0_atf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K49211735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85597
BRD-K73579545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72561
BRD-K49108064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20354
CRCGN017_MCF10A.WT.HP_24H:P08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.73825
BRD-K28565184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.6067
BRD-K07276273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19394
GSE146074_6_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SLC35E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22575
BRD-K68305833	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04837
ZBTB11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0743
TAPBPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02247
CRCGN010_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4713
CRCGN009_HEPG2_24H:H02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01541
CRCGN011_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.681
GSE202434,GSE202438_8_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE146982_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE223334_3_v_0_bcl11b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE183271_5_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K71005143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0437
Nkx3-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.1318
GSE161295_2_v_3_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.3364
BRD-K32782599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	6.28547
CRCGN015_MCF10A.WT.HP_24H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.9618
BRD-K46737746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03425
PMC9248879-supp_gr.275831.121_Supplemental_Table_S2.xlsx-TP53-dependent_proteins-GeneName_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN008_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.8013
BRD-K62682892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05094
GSE146982_4_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE48812_3_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
PM20D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30467
BRD-K13196166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02541
BRD-K84846130	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23036
GSE248883_0_v_1_shmt2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_3_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PAX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0007
BRD-K47776393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55216
IRF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32434
GSE158632_2_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN009_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.65482
H2AC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74228
GSE178714_6_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210377_0_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE216043_10_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE148066,GSE157787_9_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K52037352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23985
BRD-K11700411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10679
BRD-K76487707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06048
GSE205163,GSE205164_3_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE189653,GSE203344_4_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216538_1_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_3_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K59049030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34423
BRD-K11757577	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39516
PMC5058748-oncotarget-07-31177-s002.xlsx-ZNF224_gene_peaks_promoter-Table_S3_Genes_that_contain_a_ZNF224_enriched_region_within_1_kb_of_the_transcription_ZNF224	Rummagene Transcription Factor Associations 2026	1.0	null
GSE147876,GSE147877_4_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE130246_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K96925976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24576
BRD-K10416099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07505
GSE48812_8_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE118794_0_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE225141,GSE225143_2_v_3_mettl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K15714771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12269
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.8621
GSE110178_4_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3274
GSE162739_2_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205163,GSE205164_2_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K83209781	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33684
RPS27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03212
CDCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26905
BRD-K44126416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08601
BRD-K52136059	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00071
GSE146612_2_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.68325
BRD-K23997756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24794
BRD-K70050144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25226
GSE211215_1_v_0_pemetrexed_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN012_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.0132
PMC3355086-pgen.1002728.s003.xlsx-Tabelle1-HEY2_downregulated_HEY2	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN014_HEPG2_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.89245
496100323_FWM_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.23227
RNPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3886
BRD-K88104720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0355
GSE241701_1_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K29379469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1918
BRD-K56879482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.93026
GSE178714_5_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142588_2_v_1_cinobufagin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.19086
GSE124304_1_v_0_abl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN009_HEPG2_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.7497
BRD-K52175660	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54425
GSE199606_5_v_4_csf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K11269634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49915
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-NB4-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_NB4_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE134214_0_v_1_ell2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K23585987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4863
BRD-K93927229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29228
BRD-K45508763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03196
GSE186483_2_v_0_lrrk2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K23835343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11992
CRCGN016_MCF10A.TP53.M_24H:O18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.41752
CRCGN016_MCF10A.TP53.M_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.40468
GSE226544_1_v_0_hnrnpa2b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE206400_1_v_4_nusinersen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE155852_0_v_2_apigenin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PRXL2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23711
BRD-K06743908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12774
Brain - Putamen (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.02636
GSE199606_5_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE219274,GSE219276_3_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HEY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0081
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.9764
CRCGN015_MCF10A_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.14105
CRCGN017_MCF10A.TP53.M_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.34662
GSE151782_4_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K40219231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66295
KANSL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.343
GSE239844_1_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DCAF12L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2286
BRD-K33637419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86511
MCM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04997
GSE129293_0_v_1_chd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K22940496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84703
GSE181865_0_v_1_zbtb46_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148647_4_v_2_scgb1a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K76115264	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61317
BRD-K36171309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25315
GSE148066,GSE157787_5_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE226316_0_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10592471-NIHMS1912771-supplement-7.xlsx-D-HEp3-Enh_vs_AA-up_genes-D-Enh_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
YIPF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09678
GSE149075_3_v_11_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.16232
BRD-K32943037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28223
BRD-K96320811	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05492
GSE124375_13_v_0_chd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
7608_RUVBL2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.15906
CRCGN017_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.37425
GSE48812_2_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DMAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0347
BRD-K20203758	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5331
DCAF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10939
GSE123943_4_v_5_sox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.54597
BRD-K12986423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58963
BRD-K27616003	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40584
GSE188721_3_v_4_mesp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K22485581	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33396
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.2406
GSE130676_0_v_2_suds3_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.82278
CRCGN012_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.88702
kasugamycin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0776
CRCGN016_MCF10A.TP53.M_24H:P21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18182
GSE200673,GSE200691_1_v_4_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.WT.HP_24H:M01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.41092
SERF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09243
GSE215351,GSE215794_1_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:B06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.33249
RPL29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25678
NVL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08376
GSE211286_1_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146074_9_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_12hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF708	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.6137
BRD-K59239787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63254
BRD-K46730958	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13571
BRD-K67535324	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2308
GSE196540,GSE196542_2_v_0_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.4873
GSE114258_3_v_2_foxk1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8998
BRD-K30038014	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15704
DAB2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89174
BRD-K65774385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09134
6793_PRPF31_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.517487
BRD-K44328896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0264
GSE124471,GSE124488_1_v_0_lats1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K82399478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5998
BRD-K28623804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6392
GSE125403_7_v_6_venetoclax_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DHX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07493
ZSCAN29	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4778
GSE206870,GSE206872_1_v_5_ascl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5226
GSE199606_2_v_7_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
496100463_FWM_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.53762
BRD-K09903493	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95486
GOLGA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01713
GSE112760,GSE112767_4_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ECH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14847
GSE136233,GSE136234_0_v_1_zpbp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K91500340	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83592
GSE174418,GSE174421_2_v_3_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE164463_0_v_1_pax6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158715_3_v_0_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_WHI-P154_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.017078
GSE207978_1_v_0_rai1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.5133
GSE160765_2_v_1_twist1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K82791632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.19671
BRD-K28008176	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3827
BRD-K47841020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04345
CRCGN017_MCF10A.WT.HP_24H:N03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.51591
GSE232786_1_v_0_otud1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SOWAHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8637
BRD-K26431593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.27541
BRD-K83895653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18298
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.1702
GSE244072_10_v_8_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SYVN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83401
K562_AMG-900_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0154611
GSE192663_3_v_2_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE220097_4_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K61807670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34154
GSE142210_9_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE120413,GSE120447_4_v_5_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213996_1_v_0_fhl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K73573090	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37576
GSE202434,GSE202438_13_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K97128200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78817
BRD-K18345677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7167
GSE175787_5_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE248045,GSE248046_4_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K02190643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47399
GSE104508_2_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K05074020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4577
GSE111102,GSE111105_8_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE221020,GSE221023_2_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K47001624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.29542
BRD-K24246830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38405
GSE202434,GSE202438_10_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.91905
BRD-K62983405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12428
NKAIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24321
GSE242199_9_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE112860_3_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE226316_1_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PRSS35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2806
GSE178227_1_v_2_tet1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K38282015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15294
GSE118794_0_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Golgi to plasma membrane transport	GO Biological Process Annotations 2025	1.0	null
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4602
BRD-K31778201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.9434
GSE48812_3_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K78395012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10884
BRD-K61726189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04566
GSE149264,GSE149267_4_v_5_trp53_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_24H:L18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.28691
GSE148066,GSE157787_9_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN012_HEPG2_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02989
BRD-K71472853	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.34253
KIF4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41196
GSE130081,GSE130082_5_v_10_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K47998973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31169
GSE235550_1_v_0_hspa9_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE218580_1_v_5_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:J07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1036
GSE199538,GSE199539_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100448_TCx_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.69919
BRD-K96547094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20833
BRD-K64663625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96914
2624_EML2_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.608077
BRD-K43387144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12425
GSE114232_8_v_6_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142210_2_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
INTS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63854
SOHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7838
KATNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13985
BRD-K80630598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0988
GSE211286_7_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN010_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.62594
496100462_PCx_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.15211
BRD-K66453893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.28809
BRD-K74705119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51318
GSE112760,GSE112767_1_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K25907192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09897
BRD-K49864183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24818
BRD-K95010912	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54832
BRD-K84386253	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03503
CRCGN009_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.35644
GSE196835_0_v_1_ddx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GPATCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6719
HFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70783
BRD-K89362730	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41423
496100291_TCx_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.07376
CRCGN015_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5633
BRD-K77591784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85054
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.00071
GSE154246_2_v_0_haspin_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K48900723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2099
GSE221327_4_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE195513_0_v_3_cpeb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE159893_2_v_0_genistein_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE178714_5_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K58846294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26684
BRD-K12106433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.55326
CRCGN015_MCF10A.TP53.M_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.33475
BRD-K23762204	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72379
CRCGN014_HEPG2_24H:I12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.94015
BRD-K77718491	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07358
GSE185163_5_v_2_clic4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K74794014	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21389
GSE210580_0_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10592471-NIHMS1912771-supplement-7.xlsx-D-Enh_vs_AA-all_DE-D-Enh_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE179880_7_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_Clevudine_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0144416
GSE171175,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:E20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.05166
BRD-K47087435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14546
GSE135514_8_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.4647
GSE195568_3_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN010_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.40444
CRCGN009_HEPG2_24H:M19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6534
BRD-K60759770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96487
CRCGN015_MCF10A.WT.HP_24H:F16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8987
BRD-K25573760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47461
BRD-K76147162	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61969
BRD-K09473191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11803
CRCGN016_MCF10A.WT.HP_24H:D04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.4778
GSE118794_5_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN012_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.12279
BRD-K90793170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1155
Brain - Substantia nigra	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.15866
CRCGN010_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8498
GSE190235_1_v_2_foxo3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6321
GSE205316,GSE205317_0_v_1_nrip1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE116354,GSE117379_2_v_4_cox2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC3023804-pone.0016344.s008.xls-S3_High_Confidence_PPAR_Peaks-Primary_Gene_Name_PPARA	Rummagene Transcription Factor Associations 2026	1.0	null
SLC31A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24101
CRCGN008_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7417
GSE120413,GSE120447_0_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K36944891	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10729
BRD-K16705434	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19637
CRCGN016_MCF10A.TP53.M_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21283
CRCGN017_MCF10A.WT.HP_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.45335
BRD-K64860451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32664
HIF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5857
CRCGN012_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.05354
BRD-K77214780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.36884
CRCGN017_MCF10A.TP53.M_24H:G11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3251
GSE112761,GSE112767_2_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE171269_1_v_4_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K54881917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50801
GSE196671_5_v_1_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:A15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0498
SLC30A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48643
BRD-K52054012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36687
CRCGN015_MCF10A_48H:M22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22118
BRD-K89175823	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71846
GSE205163,GSE205164_5_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_9_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2895
PMC5159535-supp_gkw757_nar-00810-met-z-2016-File016.xlsx-S9_SOM-Unnamed_3_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158834_0_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K11610091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00317
GSE126621,GSE126920_1_v_0_dppa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE48812_9_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE157383_6_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202434,GSE202438_4_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FUT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05059
BRD-K28079391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35126
CRCGN009_HEPG2_24H:F20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.0141
BRD-A50913845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01332
GSE159937_2_v_0_tfcp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K12347309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56288
GSE146072_0_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69061
TAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03268
GSE184210_0_v_3_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.21993
GSE175787_8_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE109285_5_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE205163,GSE205164_1_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
HINFP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9843
METTL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43627
GSE202434,GSE202438_12_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K59772014	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.22162
CRCGN008_HEPG2_24H:A07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.03545
BRD-K68732617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16724
GSE201270,GSE201272_5_v_1_mybl2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE242049_1_v_0_txndc5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN013_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.16062
GSE129370_2_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE147876,GSE147877_2_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_Sirtinol_10µM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0137768
BRD-K50985475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71416
GSE246195,GSE246305_1_v_0_sin3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K13486159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.03794
BRD-K76176797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05139
GSE248045,GSE248046_0_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN010_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.24189
BRD-K18984088	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0147
GSE198165,GSE198166_7_v_1_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K01067435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74391
SPDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23729
GSE173810_0_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE151083_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216538_5_v_6_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A_48H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.39316
HIPK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51474
GSE178714_3_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN009_HEPG2_24H:N19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00679
BRD-K60429174	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17514
BRD-K95508535	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.35559
BRD-K34797601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.51578
CRCGN011_HEPG2_24H:L14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.40135
GSE98755,GSE98756_1_v_0_fbxl19_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211983_0_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN009_HEPG2_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2319
BRD-K30172718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13265
SPIN2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35496
GSE242049_1_v_0_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:C08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02655
CRCGN016_MCF10A.TP53.M_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.27328
CRCGN016_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.3682
PISD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17435
Nkx2-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.8839
CRCGN016_MCF10A.TP53.M_24H:O20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.31999
BRD-K72125659	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68826
GSE118939_1_v_0_nras_human	RummaGEO Gene Perturbation Signatures	1.0	null
ractopamine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0132
BRD-K33438042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.27416
GSE243683_0_v_1_s100a16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.04005
GSE126621,GSE126920_1_v_3_dppa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K65291993	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14108
GSE199255,GSE199356_3_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
establishment of protein localization to plasma membrane	GO Biological Process Annotations 2025	1.0	null
GSE69869_0_v_1_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K84990603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22712
BRD-K81181894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42668
GSE202434,GSE202438_15_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE142210_9_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K06203116	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28438
BRD-K48235533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24997
GSE189683_3_v_0_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K89637993	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55509
GSE95688_1_v_0_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K62018188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.88245
GSE175787_13_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.81935
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_3hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN014_HEPG2_24H:P01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.52495
CRCGN015_MCF10A_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.80676
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K02624294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10466
BRD-K38519585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0274
GSE162739_4_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K95729740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.46246
BRD-K50713036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22549
VCX3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32482
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.3929
BRD-K20053005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16527
BRD-K41707029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01295
GSE201877_1_v_0_yap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211128_9_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN013_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.49139
PEBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03792
BRD-K46155894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48556
GSE183271_2_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.1063
HES4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08945
GSE214823,GSE214824_0_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202933_1_v_0_ugt2b28_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2972
BRD-K77775127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10817
GSE151612_0_v_7_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K15444511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11571
GSE214823,GSE214824_6_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE81193_3_v_5_irf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE103068_0_v_1_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN010_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.65848
BRD-K38190084	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11173
GSE159937_1_v_0_tfcp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K72135113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55706
BRD-K87158974	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18317
496100339_HIP_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10478
GSE149075_8_v_0_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K72224143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65736
BRD-K83699731	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73082
GSE128730_4_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.64795
BRD-K76788397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70419
GSE173810_4_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.4196
GSE239844_7_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE110178_2_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN013_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.02227
NUP93	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31976
GSE228106_0_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:E04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.61513
FAM32A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21502
BRD-K90858591	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0469
GSE148066,GSE157787_11_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN010_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.27295
GSE179974_3_v_0_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CGB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89756
CRCGN010_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.20575
dendrite	GO Cellular Component Annotations 2025	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.20605
GSE189653,GSE203344_5_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE242199_6_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K94442101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22814
BRD-K81206010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60119
A549_Nilotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0173736
PSMA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29567
CRCGN010_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.59382
GSE122101,GSE122103_3_v_4_ssu72_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.86164
NME2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09511
POLR2G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08992
BRCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32467
4578_LIG1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.578595
ZFP57	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5384
CENPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92713
GSE89767_7_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TLE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2746
BRD-K61733751	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01808
GSE185163_3_v_1_clic4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE206226_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE102505_6_v_2_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K68540120	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.36019
COPZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24395
GSE229580_0_v_3_creb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K53619784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19834
BRD-K38431962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.34089
CRCGN010_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2111
GSE187005_5_v_2_atf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AURKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19399
BRD-K79734831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26936
8332_SPC25_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.560056
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-4_E2F8-Gene_E2F8	Rummagene Transcription Factor Associations 2026	1.0	null
GSE136627_3_v_1_hdac4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE165647_5_v_1_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157282_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.79035
496100461_PCx_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.97281
GSE162892_4_v_0_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nuclear speckles	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
4958_MED8_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.530113
CRCGN016_MCF10A.TP53.M_24H:F14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.08295
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.00404
BRD-K54285478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0834
CRCGN011_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.57145
BRD-K24081812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.88189
BRD-K73840377	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1626
GSE135514_8_v_3_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.45795
PAX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4355
GSE158632_3_v_4_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K92462786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02378
BRD-K49923205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58717
GSE234637_3_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE112860_3_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.4664
NCOA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06167
CRCGN013_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.52554
CRCGN015_MCF10A_48H:A18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.10393
PMC6977700-aging-12-102667-s004..xlsx-Stage1-The_identified_3126_dysregulated_LmiRM-CTs_in_stage_1_of_MI_1_day_of_MI_using_our_method_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN009_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.40019
PMC7346435-12864_2020_6860_MOESM6_ESM.xlsx-H1_ZF_Oocyte_Specific-Gene_SymbolH_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K32345392	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06146
GSE214931_4_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GFM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96137
GSE216043_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7346435-12864_2020_6860_MOESM6_ESM.xlsx-H1_ZF_Oocyte_Specific-GeneH_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE239844_1_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE130690,GSE130692_1_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN013_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.83693
BRD-K09248459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18479
BRD-K76544773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07274
BRD-K97224540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67285
CRCGN012_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.49672
PMC12103066-FEBS-292-2688-s001.pdf-171-SREBF1_SREBF1	Rummagene Transcription Factor Associations 2026	1.0	null
KANSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09876
DDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04132
ZNF770	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.0107
BRD-K70618663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72645
BRD-K64483847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1798
GSE169571_0_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.10268
BRD-K16891407	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11311
2925_FAM50A_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.50185
GSE113005_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K55218521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07587
CRCGN011_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.2999
GSE110178_5_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K69093885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03279
GSE147876,GSE147877_2_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0087
GSE195568_3_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE190186,GSE190188_8_v_10_apoe_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_2_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
GSE216043_10_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE48812_0_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K92399035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59858
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01602
GSE160246_9_v_5_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.8371
PMC7833686-mmc5.xlsx-e_q1en30_v1-CEBPD_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
PIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22514
Brain - Hippocampus	GTEx Tissue Gene Expression Profiles 2023	1.0	3.03868
BRD-K44062658	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49318
BRD-K75206417	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.817
CRCGN011_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.44725
MTFMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13561
1197_CARS_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.766005
GSE103297_1_v_0_glis3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92043
trans-Golgi network	GO Cellular Component Annotations 2025	1.0	null
CRCGN017_MCF10A.TP53.M_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.41076
GSE157036,GSE166411_3_v_1_halofuginone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE189683_1_v_2_rif1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K64353626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78781
BRD-K84423439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49764
BRD-K22668106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30304
ZDHHC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37509
BRD-K94247332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0418
BRD-K62504352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78416
GSE118794_5_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K18865369	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05257
GSE62974_1_v_0_epas1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE234637_3_v_0_ikzf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	106.429
BRD-K82102352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00675
GSE206502_2_v_1_igf2bp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K21483524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88185
BRD-K93051667	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62699
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.1287
BRD-K05411364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15047
BRD-K96779993	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15376
BRD-K18887540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23682
GSE158632_3_v_5_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:H10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2392
GSE124097_3_v_0_trem2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE139966_4_v_3_figla_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE144115_2_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199541_2_v_4_mbd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN013_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13126
BRD-K65602491	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.0815
BRD-K32235162	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.56786
BRD-K04706894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09369
CRCGN016_MCF10A.TP53.M_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9428
BRD-K69777784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44304
7185_RBM8A_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.515882
GSE148066,GSE157787_3_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
4950_MED27_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.549391
CRCGN009_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.99782
PHAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38751
GSE157594_6_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain - Cerebellar Hemisphere	GTEx Tissue Gene Expression Profiles 2023	1.0	3.58495
GSE74251_2_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE195582_2_v_1_pim1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
2291_DNAJC17_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.5975
GSE157594_0_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
K562_Valproic acid sodium salt_1µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0203189
BRD-K55505527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92037
BRD-K38370827	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.03825
GSE255680_2_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE195568_1_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RLIM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36248
BRD-K28247259	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16101
CRCGN016_MCF10A.TP53.M_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1975
BRD-K19830171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32496
BRD-K05734090	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14325
GSE174735_1_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.4115
BRD-K02781189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0804
GSE110178_2_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6078963-41467_2018_5311_MOESM9_ESM.xlsx-PPARD_CHIP_vs_RNA_CD34-PPARD_macrophages_Vs_RNA_CD34_OE_DEGs_PPARD	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K18077898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39821
BRD-K69423881	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00983
PMC11024925-mmc3.xlsx-Gene_lists-MV411_FOS_ChIP_and_RNA_overlap_after_10_nM_Gilteritinib_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
GSE206870,GSE206872_3_v_5_ascl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE199255,GSE199356_4_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE234514,GSE234516_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3543
BRD-K73678117	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57947
BRD-K75985122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57359
GSE93124_0_v_1_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE154081_3_v_0_sildenafil_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE146074_6_v_3_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K13817284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.23098
BRD-K03243737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47805
GSE199255,GSE199356_0_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE71674,GSE71676_0_v_2_cbfa2t2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE128232,GSE128233_1_v_0_phf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN013_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.02215
CRCGN010_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.97404
BRD-K06876397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49161
K562_BMS-911543_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.019671
K562_AMG-900_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0149026
BRD-K72060858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.3273
BRD-K07689069	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22557
CRCGN015_MCF10A_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.6647
PMC10879698-mmc1.pdf-12-ZNF230_ZNF230	Rummagene Transcription Factor Associations 2026	1.0	null
exocytic vesicle membrane	GO Cellular Component Annotations 2025	1.0	null
CRCGN009_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.45238
BRD-K65440031	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32936
GSE210101,GSE210114_11_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.11595
BRD-K48670593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89304
CRCGN013_HEPG2_24H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.29587
GSE196699_2_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HES1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9367
DBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92937
6709_PPY_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.772634
LYSMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.328
BRD-K06842972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6356
GSE163297_0_v_2_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K04834648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13145
BRD-K94409042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03486
496100330_PCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.72723
PNPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36845
BRD-K63864604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18648
GSE102505_6_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DACH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09583
ZNF443	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22418
A549_Fasudil_100nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0155029
GSE226584,GSE226589_2_v_0_ezh2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3719
BRD-A44068497	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54824
SMC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20898
CRCGN013_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.79274
BRD-K36709933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13514
GSE192663_3_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10641274-mmc2.xlsx-FOXK1_Insulin-ENSEMBL_FOXK1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158853_0_v_1_hmgcs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE123943_1_v_3_sox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K01100412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19383
K562_Nilotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.011609
GSE123022,GSE123030_2_v_0_trem2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K49042040	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22063
GSE226316_6_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE113734_1_v_0_qprt_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K71109636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17355
GSE199255,GSE199356_3_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF93	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	136.625
BRD-K67390061	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92521
GSE180147_0_v_1_itga5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K31575995	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03379
GSE178714_5_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PDCD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53192
SIAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47984
GSE179974_3_v_2_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K48050202	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31717
GSE111102,GSE111105_4_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ARNT::HIF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2212
496100445_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02257
K562_S-Ruxolitinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0148739
GSE172146_2_v_0_mettl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:L09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05385
BRD-K31462164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05637
GSE142210_3_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_EC_CSc_vs_NB_2D_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE144115_1_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211983_0_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.714
BRD-K47849061	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53012
CRCGN017_MCF10A.WT.HP_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.102
CRCGN009_HEPG2_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.88209
GSE149075_3_v_0_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K74779337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17798
GSE125014_6_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3M_Peaks_YAP1MAMLD1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE227891_5_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K05561348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.18041
PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_PSc_vs_NB_2D_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE128730_4_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_3H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.33002
BRD-K08730943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32659
GSE199255,GSE199356_4_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE123943_2_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN012_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.20523
GSE146612_1_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202434,GSE202438_15_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE146074_10_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K67177501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68865
USP22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34943
GSE186483_6_v_4_lrrk2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE114883_0_v_5_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE112761,GSE112767_4_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K91766181	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.68067
A549_Dasatinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0145962
GSE125014_1_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE192771_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE210655_3_v_4_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE162892_4_v_2_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100438_PCx_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.80192
CREB3L4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6213
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7291
BRD-K46412655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10307
GSE160246_2_v_1_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_15_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K20918933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60859
GSE104508_0_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE242199_9_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE178714_6_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199606_2_v_7_csf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:B08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4675
BRD-K59491482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36606
BRD-K72774661	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12812
GSE148066,GSE157787_11_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100551_PCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.03022
Adipose - Visceral (Omentum)	GTEx Tissue Gene Expression Profiles 2023	1.0	3.28194
BRD-K65320638	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14911
K562_Meprednisone_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0176313
FGF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04674
GSE192771_2_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K17059629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15873
GSE112761,GSE112767_4_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K16190564	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00307
CRCGN009_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.05998
NARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86605
YTHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22947
BRD-K18599462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03441
BRD-K28924192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25077
GSE206342_1_v_0_kpna2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN009_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.50826
3916_HOXC6_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.825295
CRCGN014_HEPG2_24H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.29983
GFI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13527
GSE198165,GSE198166_9_v_1_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K28937085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.87152
PMC13137955-ijbsv22p4243s2.xlsx-Sheet1-hTFtarget_E2F3_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN012_HEPG2_24H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06291
PMC7291745-12967_2020_2407_MOESM2_ESM.xlsx-Table_S1D_CCF_pairs-locus_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
496100642_PCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.59413
BRD-K72161690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15203
GSE179031_0_v_2_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE185519_1_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE48812_4_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
PCNT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04139
GSE169356_2_v_1_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K66793411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00858
BRD-K69942587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15643
GSE236072,GSE236075_2_v_1_ccr6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K68056389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07669
GSE158502,GSE158506_3_v_0_fat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CDK13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06309
CRCGN008_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.27715
BRD-K46291400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13574
GSE154464_1_v_2_cdk6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE138938_1_v_3_foxp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_6_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
K562_Avagacestat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0144294
BRD-K05041614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10226
BRD-K13488816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51155
5927_OGDH_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.93602
BRD-K97485956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16248
BRD-K73183447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06321
BRD-K42987166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0163
GSE121043_0_v_1_aldh1a1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K31883758	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07023
GSE142210_11_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ACP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08919
GSE173873_4_v_6_stra8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K07388954	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83858
CRCGN017_MCF10A.WT.HP_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.45465
BRD-K60758969	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00635
CRCGN009_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.1861
GSE158834_11_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE195743_1_v_4_lhx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
4932_MED12_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.727021
PMC8190596-mmc2.xlsx-RUNX1_mut-RUNX1_mut_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN017_MCF10A.WT.HP_24H:E10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.5537
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.0203
TBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.747
GSE146982_0_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DVL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98004
BRD-K12909905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28712
GSE175787_5_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.37
ARHGEF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55819
BRD-K34739404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48115
BRD-K01022714	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70125
GSE202744_1_v_0_toyocamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K35088248	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00017
Golgi to plasma membrane protein transport	GO Biological Process Annotations 2025	1.0	null
GSE171401_1_v_2_adnp_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K43240808	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.26158
GSE244072_10_v_3_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199255,GSE199356_6_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151782_1_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_2_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE88819_6_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE127790_10_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SFN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01079
GSE108614,GSE108615_3_v_2_setd1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE162892_4_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PHB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44215
C19orf73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17441
GSE113734_3_v_0_qprt_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE147876,GSE147877_4_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:A08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.07045
BRD-K80921954	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04091
BRD-K16626032	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01566
AP5M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82543
PMC10641274-mmc2.xlsx-FOXK1_Insulin-SYMBOL_FOXK1	Rummagene Transcription Factor Associations 2026	1.0	null
PIK3C2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08468
BRD-K06355852	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9698
CRCGN013_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.0461
CRCGN014_HEPG2_24H:H18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1899
CRCGN011_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.01335
BRD-K19103580	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51072
PMC3023804-pone.0016344.s008.xls-S3_High_Confidence_PPAR_Peaks-Primary_Gene_ID_PPARA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE84922,GSE84924_0_v_1_sall4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MPST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42548
BRD-K86192746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42053
GSE230263,GSE230265_0_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_EA_PCa-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN012_HEPG2_24H:G02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.31803
CRCGN013_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.62815
clopidol	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01581
RBM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05243
BRD-K63436783	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16662
GSE215351,GSE215794_1_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE226249_2_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K83463455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14886
IGBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63573
CRCGN010_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5588
CRCGN008_HEPG2_24H:O17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1793
BRD-K22608982	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02387
BRD-K41207293	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81499
TFAP2E	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.7144
PMC9013323-13577_2022_685_MOESM7_ESM.docx-3-ZFHX3_ZFHX3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE196117_1_v_8_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100504_TCx_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.12674
GSE178714_3_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE130081,GSE130082_5_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K06537903	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07532
BRD-K10135449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21921
EEF1AKMT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15674
CRCGN017_MCF10A.WT.HP_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6843
BRD-K70193997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13317
CRCGN014_HEPG2_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.68575
CRCGN013_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.54765
GSE116354,GSE117379_3_v_5_cox2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE48812_8_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
TRPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10458
PMC11392820-41556_2024_1475_MOESM3_ESM.xlsx-Supplementary_Table_9-Supplementary_Table_9_Expression_level_of_OTX2_targeted_genes_n_999_related_to_Figure_6_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K24308170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.27593
GSE158834_11_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K71533707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15505
GSE110178_1_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
No annotation - 6	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
TCFL5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6801
BRD-K42150052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43055
HES5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6434
CRCGN011_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25005
496100485_PCx_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.6968
BRD-K07928699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.90685
GSE198165,GSE198166_8_v_1_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
4955_MED4_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.508346
MED12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91292
BRD-K74314059	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34548
C1orf21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04361
GSE48812_2_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K44626845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.22615
GSE129370_0_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.97815
BRD-K90004516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11607
BRD-K98586629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10018
BRD-K75539052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09574
GSE112763,GSE112767_0_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE235066_4_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN012_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.99861
CRCGN015_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.19395
CRCGN011_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.8669
CRCGN014_HEPG2_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.03662
CRCGN016_MCF10A.TP53.M_24H:F05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.75761
GSE168596_1_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN013_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9938
BRD-K25149224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59249
neuron projection	GO Cellular Component Annotations 2025	1.0	null
IRF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40249
BRD-K09871160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37822
BRD-K95148987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26389
CRCGN016_MCF10A.TP53.M_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.64173
CRCGN015_MCF10A_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.97541
GSE122067_2_v_1_mtch2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SAAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27467
CRCGN015_MCF10A.TP53.M_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.4745
BRD-K34703146	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.33663
GSE138019_3_v_6_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE178292_0_v_2_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE210770_0_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE224969,GSE224971_3_v_1_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE185519_3_v_5_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K93032100	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16331
CRCGN012_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.28367
PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_SYMBOL_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
BCAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05057
GSE211983_1_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2366
GSE200673,GSE200691_1_v_5_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE57871_5_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE196699_7_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE48812_9_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6829
DDX52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00549
GSE242199_6_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN009_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.67301
GSE154337_0_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE180377_2_v_1_lipa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE235390_4_v_2_lurbinectedin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K57115335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9296
CRCGN015_MCF10A_48H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26745
BRD-K86077185	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26795
BRD-K90697694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60381
BRD-K32043305	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63954
CRCGN011_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8513
CRCGN017_MCF10A.WT.HP_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7188
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K84613654	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16771
Prdm14	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.8749
CRCGN011_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.5276
CRCGN016_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.73872
CRCGN008_HEPG2_24H:B06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.07485
BRD-K72314068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29543
BRD-K84932026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39454
GSE48812_2_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NOBOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20679
KLHDC8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37774
BRD-K47349869	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.13015
GSE107956,GSE107957_0_v_1_ythdf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE200352_5_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE171401_1_v_0_adnp_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SOX12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7938
MALT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09908
GSE112860_5_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K20984459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08074
GSE162892_4_v_2_sox9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K51207618	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77194
CRCGN011_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.80395
PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_ENSEMBL_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K51919278	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22975
BRD-K17821077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39712