association	dataset	threshold value	standardized value
BRD-K36730085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32279
BRD-K43700313	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90158
GSE85880,GSE85881_0_v_1_tretinoin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NDUFA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16033
JEG3	DepMap CRISPR Gene Dependency	1.0	3.71441
RAN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50784
FKBP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08249
BRD-K70566686	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08735
CRCGN009_HEPG2_24H:N19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01879
CRCGN016_MCF10A.TP53.M_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.37774
DMBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06609
CTAGE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34157
GA-88-CF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.577586
BRD-K19958830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02202
BAHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88146
HEATR5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01131
TRAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50119
Basal ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC12518476-10067_2025_7574_MOESM9_ESM.xlsx-Sheet3-RNAseq_SJIA_KD_inter_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE178255_1_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K96491043	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26845
PTK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38169
BRD-K12524104	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.48221
RPEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97241
GATD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62177
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.2484
BRD-K37459038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03026
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2025	1.0	null
CCDC43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04891
PORCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02534
STK24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53897
G protein-coupled receptor dimeric complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.001
CRCGN010_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.06465
PMC9287735-mmc7.xlsx-PharmMapper-NR1D2_NR1D2	Rummagene Transcription Factor Associations 2026	1.0	null
GOLGA6L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68182
GC-04-UF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.405544
HUWE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06203
Prdm15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	43.262
BRD-K26689527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1364
RAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.598
Apparent mineralocorticoid excess syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.114
GSE142684_4_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH82	DepMap CRISPR Gene Dependency	1.0	2.918
BRD-A03182941	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.28636
Parasympathetic nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.69
GSE74528_0_v_1_trex2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ENTREP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67309
HCC1428	DepMap CRISPR Gene Dependency	1.0	2.50176
BRD-K16266179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76183
G3BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3421
BRD-K80679698	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48517
LU65	DepMap CRISPR Gene Dependency	1.0	2.22937
PIERCE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16973
BRD-K10540354	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12653
FOSB::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7804
CRCGN015_HEPG2_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.31636
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-GATA4_GATA4	Rummagene Transcription Factor Associations 2026	1.0	null
Developmental and epileptic encephalopathy 33	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.568
ZNF45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38324
BRD-K34851865	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07734
Oculocutaneous albinism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.319
PPDPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03801
DA-33-CX68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.227647
Idiopathic scoliosis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.34
GSE203158_1_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KLC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16502
ZNF512	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27589
BRD-K92981306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57133
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7372
BRD-K80921954	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06159
OLIG3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6743
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4861
abnormal mechanical nociception	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K43628610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53573
TJAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14099
GLI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44036
Avian pallium	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZNF292	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28047
SFRP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52761
GSE181513_2_v_1_usp7_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K99455613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10172
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4125
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.3679
BRD-K19946529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60914
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.7875
PDZD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76738
BRD-K39813155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72066
GSE214248_0_v_1_cxcl8_human	RummaGEO Gene Perturbation Signatures	1.0	null
TMEM231	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25074
CRCGN016_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.12023
BRD-K10876822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69722
PIWIL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24069
BRD-K68605096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.34844
CME1	DepMap CRISPR Gene Dependency	1.0	2.02347
BRD-K25608271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5044
BRD-K92195351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00741
GSE124932_2_v_1_sarm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211983_1_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GF-46-LK68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.357671
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.323151
GSE217363_6_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HEY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75274
Hypertension	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.8
TCF21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5825
GSE88819_3_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.WT.HP_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.6981
BRD-K81110981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29472
CDC14C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63896
MMS19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05468
DNPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93831
BRD-K43435656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07587
H3-5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89653
CRCGN011_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8096
PMC8822763-13293_2022_415_MOESM3_ESM.xlsx-ML_MR_DEG-Gene_name_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
CXXC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17286
CRCGN016_MCF10A.TP53.M_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03437
FOSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4719
RAB5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92439
GALR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03765
ELL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40135
DF-40-CD57_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.219473
UBXN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06424
TAF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59862
BA-84-TD72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.206577
ZNF568	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60321
Lewy body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.071
GSE126127_5_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3601
SP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8479
BRD-K64753899	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30379
CDCA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67777
CENPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05055
BRD-K63987422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52201
Cockayne syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.137
GSE160817_5_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE221633_3_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CDKN1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49067
SKIC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.79275
BRD-K83775558	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53687
GSE149903_3_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64776
SOHLH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77081
CC-47-VS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.220445
CRCGN008_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13605
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RAB18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84957
CAPN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16955
BRD-K82562625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2964
SCYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03484
IGROV1	DepMap CRISPR Gene Dependency	1.0	4.19526
KDSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94234
GSE111660_2_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CB-87-GT98_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.279257
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-PHOX2B-fromNode_PHOX2B	Rummagene Transcription Factor Associations 2026	1.0	null
GSE151090_5_v_3_verteporfin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE126345_4_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GLTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31868
GSE89154_1_v_0_proscillaridin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K77519898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80001
FCGRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95623
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9614
TARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06046
VPS35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21934
GSE149943_2_v_3_cd8a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Charcot-Marie-Tooth disease type 1F	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.396
GSE131649_2_v_0_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
NEO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07556
BTBD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42798
BRD-K60839995	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15638
BB-79-AG41_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.298405
CRCGN011_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2193
SAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99589
AMIGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08253
TSPAN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20272
SIN3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59345
Forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
XC-61-SE50_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.374693
GSE114992,GSE114993_7_v_3_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NIPBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70421
GSE119498_0_v_10_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BA-95-YU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.302108
BRD-K07482874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79537
BRD-K23800773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59867
ELOF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03639
BRD-K13350372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80784
BRD-K86855109	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.83568
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1737
MM386	DepMap CRISPR Gene Dependency	1.0	2.14945
BRD-A24369193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15883
GSE212330_1_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IB-33-TE51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.696501
GSE178714_6_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A52024592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42695
GSE109913_1_v_2_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TNIK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12203
FB-66-UU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.10296
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4576
GSE174418,GSE174421_2_v_3_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IL17RC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60218
BRD-K87776049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82688
phloridzin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40839
ABHD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5093
Digestive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CRCGN015_HEPG2_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.08663
GSE201520_8_v_3_inhba_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_24H:L18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.37998
C1QTNF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76628
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2121
GSE182921_0_v_1_slit2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61004
KP2	DepMap CRISPR Gene Dependency	1.0	2.95406
GPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22996
GSE65617_5_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GDI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50421
ZNF277	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36372
IFITM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6632
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.8495
HDMYZ	DepMap CRISPR Gene Dependency	1.0	2.04322
BRD-K71486446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13715
BRD-K18031793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03018
CRCGN015_HEPG2_48H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19705
PRAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11753
SNCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25335
CRCGN012_HEPG2_24H:G07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.809
BRD-K95350313	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50953
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4
BRD-K42716291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20005
BRD-A03940741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12021
GPR37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40885
Cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K99833695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31587
ZDHHC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75209
BRD-K79402882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12051
KIAA2026	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89814
LMBRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87378
Long-projecting GABAergic cell_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
BRD-K89637567	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.029
GSE114992,GSE114993_7_v_11_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Atf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.4643
ATIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56334
BRD-K25842662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14201
BRD-K67399222	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50523
BRD-K90349877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21564
CRCGN015_HEPG2_48H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.89233
CRCGN015_MCF10A.TP53.M_24H:F17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0046
GSE180147_0_v_1_itga5_human	RummaGEO Gene Perturbation Signatures	1.0	null
METAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69114
Focal epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.012
ECE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62606
FAHD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41127
GSE108326_1_v_0_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K23280067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73433
BRD-K91548063	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54199
BRD-K76672145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62186
MYBL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.291
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.2485
GSE111245_0_v_1_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K48999921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02979
Episodic ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.082
OLIG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6646
BRD-K69350885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76461
PCDHB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.30381
DNASE2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70778
BRD-K46726368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20287
GSE239844_4_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN010_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18051
RBSN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58449
CRCGN014_HEPG2_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10613
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
G protein-coupled receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.896
PMC12660214-Supplementaryfile1.xlsx-Genes_Human_with_ATF3-binding-pain_combined_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K33805386	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68671
MTLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.509
GSE233679_12_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE142210_2_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
MT-ND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20324
GSE148252_0_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CCNE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04909
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7787
HAGH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81742
Skin - Not Sun Exposed (Suprapubic)	GTEx Tissue Gene Expression Profiles 2023	1.0	3.77649
GSE200982_0_v_2_plac8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE215351,GSE215794_1_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NPW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53963
IGDCC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41634
OE-31-YC41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.534958
BC-54-ON71_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.293016
GSE198165,GSE198166_8_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MRPS23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88304
CRCGN015_HEPG2_48H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.40566
ASMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44095
GSE233679_6_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BCAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16641
BRD-K40826084	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04406
decreased physiological sensitivity to xenobiotic	MGI Mouse Phenotype Associations 2023	1.0	null
SDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29038
BRD-K97624648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52699
KYAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30474
GSE203158_0_v_14_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CPSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56669
BRD-K29328556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78711
NR4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07529
nucleus	GO Cellular Component Annotations 2023	1.0	null
BRD-K43306617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05513
Arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.888
BRD-K63813316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25796
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.305
ZNF146	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38478
BRD-A56427952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4222
GSE149903_4_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K83300227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22442
CRISPLD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73289
GSE131798,GSE131804_2_v_0_igf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K80546581	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05851
GSE175883_0_v_1_dis3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE119345_0_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE92457_7_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SUGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46343
GSE208350_0_v_1_fgfr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ATG2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36048
GSE137177_1_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Serotonergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.618
RAB34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54239
Cockayne syndrome B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.715
ZNF165	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80365
GSE154081_3_v_0_sildenafil_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K76400756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.27927
HSCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18912
KAT14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82403
SP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01998
BRD-K19237647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20337
HSPA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66477
RPS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41909
BRD-K12399715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10524
MIDEAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33774
nucleus	GO Cellular Component Annotations 2025	1.0	null
QDPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49538
BRD-K80819226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42059
OCIM2	DepMap CRISPR Gene Dependency	1.0	3.37813
BRD-K91470977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12676
BRD-K69751974	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.31667
BRD-K51181201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11779
GSE211126_3_v_4_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GABRE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02719
POMGNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18432
COA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34234
GSE81803,GSE81912_0_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Melanosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.996
BRD-K30674856	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05828
RRP36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03985
GSE174406_2_v_1_lin28b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MISP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79202
GSE218060_2_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A61767497	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09957
BRD-K86330848	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07614
PSMF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27159
REXO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.087
BRD-K80225716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26873
GSE126402_4_v_0_tal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ELF4_ELF4	Rummagene Transcription Factor Associations 2026	1.0	null
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.776
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.7749
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2586
GSE77108_4_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF506	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4353
GSE227127_1_v_0_diclofenac_human	RummaGEO Drug Perturbation Signatures	1.0	null
E2F5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30108
SMURF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79293
BRD-K52123365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18402
DDHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77711
TTC19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.40027
SYCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11375
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1223
H3C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23516
BRD-K35404627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04462
IC-15-FM25_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.208506
GSE211126_3_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K39267498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00517
Temporal lobe epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.073
EC-62-OE64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.356876
BRD-K34252131	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11477
HDGFL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45667
Cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN014_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.36065
GSE149903_3_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1305
SOX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94505
TUBB4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32027
BRD-K32862383	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.42058
CRCGN015_HEPG2_48H:M08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.88273
OLFML2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90726
HC-74-HM63_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.370259
BRD-K27398402	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00345
KLF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09207
GSE197850_4_v_2_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3C10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01377
AE-95-UU45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.41039
GSE186287_2_v_0_ufm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ATOH7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45399
ZFYVE21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66764
SF3A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86295
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7431
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4502
NKX3-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25469
CRCGN017_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.19948
B4GALNT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1503
GSE211425_1_v_0_mettl3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE160817_5_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
ANKRD13C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55664
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0099
NCIH441	DepMap CRISPR Gene Dependency	1.0	3.11474
GC-04-UF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.08275
RAB33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11228
BRD-K87647164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28735
GSE203158_12_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.55798
ACOT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46338
RABEPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06907
GSE196699_7_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE100316_5_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K58964288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0396
BRD-K95852319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00647
Gastrointestinal tract	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K75260889	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40427
GSE160373_6_v_2_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
UPCISCC026	DepMap CRISPR Gene Dependency	1.0	2.38852
CRCGN015_HEPG2_48H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.58177
BRD-K90052868	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36952
CRCGN013_HEPG2_24H:I16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.39768
BRD-K43431234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69199
CC-44-MG29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.201056
BTN2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36976
AD-16-HL96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.888284
SIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01791
Immunodeficiency 50	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.568
GSE210580_3_v_2_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LOUNH91	DepMap CRISPR Gene Dependency	1.0	2.24925
EBC1	DepMap CRISPR Gene Dependency	1.0	8.24479
ASGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23004
DNAJC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7604
DTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94929
RCE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.47132
COLO680N	DepMap CRISPR Gene Dependency	1.0	2.56848
TWIST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32192
BRD-K94915822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07851
BRD-K20016759	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61617
GSE186151_1_v_0_methotrexate_human	RummaGEO Drug Perturbation Signatures	1.0	null
POU2AF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09754
AOC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0174
GSE89032,GSE89033_0_v_1_sfpq_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CEP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04624
MELK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56256
PRM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91129
RPP25L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5441
USB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14415
CRCGN011_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.81775
AR-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE150055_0_v_1_melphalan_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE215086_3_v_0_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K61388138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19812
GSE133329_0_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
UBXN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17196
CB-16-SY72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.25765
BRD-K64860451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95005
TFRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24084
Medial temporal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.026
AA-62-HP31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.225644
BRD-K62320774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27781
BRD-K96218803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.42345
CRCGN015_HEPG2_48H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.24435
BRD-K12683022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2681
CRCGN016_MCF10A.TP53.M_24H:M12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.29591
BRD-A25184723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16049
ZNF441	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54866
BRD-K43872193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.13529
CRCGN010_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.19235
GSE100316_0_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TNNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6236
BRD-K37510443	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17803
CRCGN015_MCF10A_48H:H22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.71957
GSE142210_2_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GAS2L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81719
GSE235644_1_v_0_fasn_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.66861
NAA16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73448
BRD-K40057256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00811
PMC6538380-elife-42374-supp3.xlsx-human-sp-ENSG00000007866_TEAD3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K05128360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29612
MRPL32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37707
ORMDL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46607
BRD-K42145213	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69696
JADE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70116
Pontocerebellar hypoplasia type 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.641
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5113
WNT5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48543
GSE210388_2_v_0_ror2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5577301-in-17-237-s001.xls-AR_downregulated_DEGs-Kidney_GDS724_GENE_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE213588_10_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MDAMB361	DepMap CRISPR Gene Dependency	1.0	5.72918
BRD-K70843862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71523
GSE188870,GSE188871_4_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
THOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11415
ZNF37A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35353
GSE198982,GSE198986_1_v_2_daunorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE159893_2_v_1_genistein_human	RummaGEO Drug Perturbation Signatures	1.0	null
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6726
ASXL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37188
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0264
WC-09-GD62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.410632
CRCGN008_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.76975
PMC12518476-10067_2025_7574_MOESM9_ESM.xlsx-Sheet2-RNAseq_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K79179851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79943
ZNF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.89731
GSE226285_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE233679_12_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE222758_0_v_4_clofazimine_human	RummaGEO Drug Perturbation Signatures	1.0	null
VAMP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52857
GSE126345_11_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.4792
BRD-K13110820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01788
BRD-K24565713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94066
CIAO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76395
CRCGN017_MCF10A.WT.HP_24H:F11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.20598
H2BK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02322
NFIC::TLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0
GSE242199_6_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142684_3_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TPRA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81793
SH3GLB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84577
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4703
BRD-K37625653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0563
BRD-K47854067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.71908
OTUD7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8295
CNOT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64595
BRD-K37356599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55184
Spinal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.34
GSE238116_1_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K78311779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02693
BRD-K86981519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78084
BRD-K83090041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06803
BRD-K45272675	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.23894
CRCGN008_HEPG2_24H:G24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.29003
GSE153836_14_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FAM86B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43507
PRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52377
BRD-K86893953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.46072
NLGN4Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78852
BRD-K21161559	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18336
PRPSAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4474
GSE169571_5_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN012_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.60073
TMEM229A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75062
TSPAN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18793
BRD-K85513337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0026
ACSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.16653
BRD-K66807670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.32436
BRD-K92359570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08959
BRD-K86946907	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44255
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8664
GSE203158_5_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142684_3_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN012_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.88333
LDAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73481
PMC10794847-mmc2.xlsx-PBRM1_KD_up-Table_S1_Differentially_expressed_genes_with_PBRM1_knockdown_in_the_progenitor_state_Related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CNMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86538
PLEKHG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45158
GSE242199_6_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4915
EFEMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81305
ZSCAN20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65085
CRCGN015_HEPG2_48H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.11325
GSE159084_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE203072_2_v_3_rpl3l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE68156_3_v_4_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.3379
DIS3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50492
Dermatome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.562
GSE94849_6_v_5_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K14392329	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64865
ULBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64885
GSE116930,GSE116935_3_v_6_hes7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE160817_3_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
EA-18-FP00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.867805
UGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98975
TRMT10C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57922
GSE211989_3_v_2_nlrc3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NPIPB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12422
BRD-K39649723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47691
AGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20013
BRD-K89063617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53488
GSE236437_0_v_3_aldosterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE197117_0_v_1_kdm6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HERC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19643
SYNJ2BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35357
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.1186
GSE211983_1_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN013_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.90538
GSE151090_2_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K82198647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.36613
BRD-K36473494	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20257
YTHDF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69484
CDC42SE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61871
GSE145915_3_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DSG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91122
SUPT16H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76573
BRD-K06146578	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07994
PLPPR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02208
PCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05631
INPP5E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06443
PPP6R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17179
ENTPD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99149
GSE211983_0_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE157555,GSE157556_0_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H4C11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97908
chr9_34663801_T_C_b38	GTEx eQTL 2025	1.0	1.1462
CRCGN015_HEPG2_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.06165
GSE108675_3_v_0_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
APLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.846
PSMD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57071
HIF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74489
COX5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47355
SYNGR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42307
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5463
LMAN2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33206
GSE185944_2_v_3_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE124471,GSE124488_2_v_3_lats1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UBE2T	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20142
GSE224096_2_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
EA-18-FP00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.256912
ZFP62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46573
GSTO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86354
PMC10794847-mmc5.xlsx-PIAS1_KD_up-Table_S4_Differentially_expressed_genes_with_PIAS1_knockdown_in_the_progenitors_state_Related_to_Figure_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142684_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE214382,GSE214383_1_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ARNT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66439
BRD-K58227367	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33401
MAVER1	DepMap CRISPR Gene Dependency	1.0	2.54147
DD-43-WW40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.313396
ONECUT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07625
BRD-K66327237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15553
BRD-K92767663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93041
BRD-K53725468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78117
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4027
CRCGN015_HEPG2_48H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.32443
ZMYND8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05058
GSE116930,GSE116935_1_v_0_hes7_human	RummaGEO Gene Perturbation Signatures	1.0	null
H2BC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55219
BE-79-QU25_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.259673
GSE169571_3_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7169
BCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60438
BRD-K05002317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57454
CALCOCO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46882
Bone inflammation disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.888
AADAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33298
Cervix - Endocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	2.93609
GSE236437_2_v_3_aldosterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
MASA syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.743
SNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00277
SLC9A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94512
CRCGN012_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.89286
STN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66008
NR0B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32387
TGFBRAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75663
GCT	DepMap CRISPR Gene Dependency	1.0	3.02323
TB-06-VB30_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.222166
FBXL22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8536
ZNF878	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11207
GSE157960_0_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.9448
PDCD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36035
EIF4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30403
FAU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03947
FGFRL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57037
GSE230354_0_v_1_rheb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ERAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14922
ZDBF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61645
CPHXL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57806
PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K68078571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47491
BRD-K48717228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.96126
BRD-K95455263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60121
GSE88819_3_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FE-10-KQ78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.500625
UBE2E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87643
BRD-K39499927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47707
GSE149880_0_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_2_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6044387__F5	PFOCR Pathway Figure Associations 2023	1.0	null
TMEM185B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48022
GSE153836_11_v_2_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
DOHH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53176
RAB6D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27261
RNASEH2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11713
GSE181966_0_v_3_has2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SH3BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59085
HA-42-TE64_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.513139
FDXACB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14479
BRD-K71415389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82245
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.9853
TSPYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39278
PDPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77849
BRD-K28122619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35679
CDY2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89653
B9D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03284
BRD-K83553001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.88456
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.1611
GSE168797_1_v_6_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
E2F8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97546
JD-47-WR37_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.201367
EN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81174
BRD-K44713204	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.87801
POLDIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10398
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.344
wc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.966
TVP23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00833
TRIR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33316
BRD-K46074482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23391
Primary immunodeficiency disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.888
PA-80-RV09_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.224682
GSE216273,GSE216292_0_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF542P	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73681
BRD-K92378241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53921
BRD-K95795676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20728
GSE169205_3_v_7_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K44921931	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16424
C3orf38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80225
GSE151090_0_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	1.0	null
RAVER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07952
TRIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01051
HC-74-HM63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.388637
CRYGD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59063
ARFGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9055
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.237465
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2692
EIF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80291
BRD-K97842654	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4214
Connective tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.888
HSC39	DepMap CRISPR Gene Dependency	1.0	10.932
preweaning lethality, incomplete penetrance	IMPC Knockout Mouse Phenotypes	1.0	null
RNASEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75488
Pancreas	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PMC11426526-ppat.1012555.s011.xlsx-DEG_MDDC_Jurkat_LPS_vs_MDDC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE169571_5_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.3792
CHRNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8056
GSE145915_5_v_4_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Rheumatoid arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.888
RELL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32824
BRD-K96288607	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08364
JAK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05473
RBBP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99937
GSE221539_1_v_3_lrrc10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IL17RD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15266
GSE143955_1_v_2_ripk1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_Jurkat_LPS_vs_DC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
KIF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24426
AFTPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10443
SNU738	DepMap CRISPR Gene Dependency	1.0	3.25807
MMP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82138
MTERF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62874
BRD-K87872414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30483
BRD-K08406395	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34844
GSE112860_3_v_2_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K76114475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10719
GSE134375_4_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
CCNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61385
Scoliosis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.34
Telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TRAPPC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15146
CIBAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49202
GSE142232,GSE142234_0_v_2_gcgr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DA-27-BW20_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.22187
MYPOP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69663
BRD-K85727265	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1041
Fallopian Tube	GTEx Tissue Gene Expression Profiles 2023	1.0	3.91848
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.8
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6324
BRD-K70302892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57087
GSE205163,GSE205164_2_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
Parasympathetic ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.897
BRD-K91341416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26487
BARX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39229
GSE216538_0_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BCL11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63618
KCMF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0074
BRD-K51498205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19626
FGFR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03947
BRD-K88498468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44146
Ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0173
BRD-K54604127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22457
PMC9630632-Table1.XLSX-diff_exp_genes-Group_1_vs_2_AND_Group_2_vs_3_NOT_Group_1_vs_3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
SMAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74006
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0539
KMS34	DepMap CRISPR Gene Dependency	1.0	7.62135
BRD-K30198800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07483
DC-93-WC67_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.202576
TCIRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60988
Bone structure disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.34
WC-09-GD62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.672452
BRD-K39342915	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73944
GSE160817_4_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
TARBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77044
OAZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4081
ARHGEF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4853
BRD-K97595801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5541
GSE226285_3_v_0_nr0b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92297
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.0826
BA-95-YU85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.256254
CRCGN012_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.8166
GSE145915_0_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NUP133	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35876
BRD-K85659077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34244
BF-79-GG96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.486006
THAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33347
GSE111247_14_v_9_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ACSBG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03525
GSE160817_2_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
CCDC102A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49627
ZSWIM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05762
UAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62178
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.9895
GSE175787_13_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K71824916	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08828
GSE185944_0_v_3_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K97576000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00394
BRD-K28247259	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54482
GSE142684_0_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K86050213	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29538
EDARADD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95107
HOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5786
BRD-K90311252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.38043
BRD-K25064302	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20024
BRD-K96280720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.38452
CRCGN011_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.743
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
KANSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66098
TINF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09194
WC-09-GD62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.715322
Sertoli cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
GSE233679_5_v_13_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K47895166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44047
CYTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.67639
RBM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84485
TLX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49997
XPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09316
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K44549496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00805
STK17A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94385
PLBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27447
CRCGN009_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.04116
BRD-K90527476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00321
GSE142684_2_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CAMK2N1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4047
NONO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87625
GSE160817_7_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
TRIO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88726
BRD-K25081075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4232
UQCR11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6181
STT3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76733
BRINP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23236
TMEM39A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5118
DNAJC28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66688
BRD-K51342021	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67646
GSE180200,GSE180201_2_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5313
BRD-K28006645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.30108
GSE195559_6_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K35222206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.13194
NCIH2126	DepMap CRISPR Gene Dependency	1.0	2.07935
Developmental and epileptic encephalopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.064
RPRML	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50076
NME4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.73313
BRD-K16136457	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12648
EBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75615
PLXNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92823
BRD-K82774801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55831
GSE248668_1_v_0_atxn1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HCC2998	DepMap CRISPR Gene Dependency	1.0	3.16903
ORC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47841
SPINT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3235
LRRC45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71063
GSE205163,GSE205164_1_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0493
BRD-K78939372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94915
ELP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13294
QE-79-XO29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.783742
BRD-K00263786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55048
CD79B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91309
GSE160817_4_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE212299_2_v_1_abi3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233679_5_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
TAF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31128
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4431
PCLAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75791
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.499
GSE149903_6_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KIF21B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45203
GSE126345_0_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE88819_3_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K43570522	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27583
VPS37C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33419
BRD-A01403444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26129
BRD-K57650037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44115
GSE160817_3_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
CLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05811
HILPDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39002
GSE224294_1_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE224096_1_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SW982	DepMap CRISPR Gene Dependency	1.0	2.20972
GSE126127_0_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K69671285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0277
MAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02908
GSE126345_2_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RSL1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44275
DEDD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66932
Arid5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.3588
DDX51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06556
GSE151829,GSE151831_5_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
N6AMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50084
BRD-K34524418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82806
P2RY11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07334
ZNF551	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81965
BRD-K29466595	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06362
PMC11769988-Table1.xlsx-Table_S3-Table_S3_SCLC-related_genes_screened_by_MR_analyses_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_R_species_not_found_in_common_genes_of_LF_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.29575
GRHL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19482
BRD-K88000297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11858
PMC12518476-10067_2025_7574_MOESM9_ESM.xlsx-Sheet4-RNAseq_SJIA_KD_up_inter_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TRIM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89866
THUMPD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60769
TMSB15A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01922
BRD-K38046923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03733
GSE153836_14_v_5_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE149943_2_v_0_cd8a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K35240878	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49999
NOTCH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99792
ZNF711	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91274
BRD-K30038014	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23283
STMN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08196
BRD-K95359959	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40663
BRD-K88559334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63333
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.101
LPGAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83651
PNMA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37753
ZNF71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00824
Corpus callosum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.63
SHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22173
CRCGN016_MCF10A.WT.HP_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.77268
CIP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30734
BRD-K09895564	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.34277
CTNNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84713
SLC30A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85873
RAB8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46424
GSE151829,GSE151831_7_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K34258713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18539
PGK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77099
GSE103068_0_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K09777330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79219
GSE233679_6_v_13_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K37596331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72876
GSE151412_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE125862_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CHML	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37986
BRD-K25097691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83457
GSE126345_9_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE69244_1_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZMYND11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36324
GSE149880_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CLK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92089
GSE212330_1_v_0_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
G protein-coupled GABA receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.112
PMC12041165-401_2025_2886_MOESM1_ESM.xlsx-Meta_CAA_vs_AD-Genes_TSHZ1	Rummagene Transcription Factor Associations 2026	1.0	null
FZD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83075
GSE217363_5_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF408	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36166
CEBPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71397
LMX1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46887
SARDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27187
MID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06925
MMACHC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42631
GSE165636_0_v_4_tofacitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RPL17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46137
PNPLA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38109
GSE226091,GSE226092_0_v_4_sall1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K54112192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50628
Mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE77108_5_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
ADAMTS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6806
TSACC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2851
PMC12297505-41598_2025_11704_MOESM4_ESM.xlsx-table_s4_veen-GSE16011_AND_TCGA-GBMLGG_NOT_Human_kinases_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CIT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09977
C11orf24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82446
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0501
MED16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89232
CCDC124	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48373
BRD-K49932469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4741
GSE111660_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE160817_5_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K75164441	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55877
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.8117
WDR26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30413
AP1S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20651
CRCGN011_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.22955
RIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47495
SPIN2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65284
VN1R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73595
GEMIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67732
BRD-K48540267	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37073
BHLHA15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0025
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K88707941	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6424
WBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.126
CA-48-SW47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.419945
ASPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10596
BRD-K53026281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91394
NFKB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6326
GPAA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39925
GSE212312_1_v_3_fbxw7_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119498_0_v_7_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE151412_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K23556321	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51813
SC-72-YW56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.417335
IPPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22585
TREX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90668
Charcot-Marie-Tooth disease axonal type 2CC	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.645
GABARAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65207
BRD-K82446079	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03139
CA-42-YI34_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.404867
ZNF22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49918
CRCGN016_MCF10A.TP53.M_24H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.93696
DIAPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22831
GSE111881_0_v_1_znf768_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_upreg-human_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CTDSP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88443
DNAJC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13568
BRD-K44126416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66424
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.462
BRD-K88739137	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55453
NFIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09165
CYBRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58902
GATA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5889
BRD-K53802078	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08051
BRD-K56106571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09082
CRCGN009_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09979
BRD-K47887272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01363
SNAP47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25281
BRD-K85664064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03939
BRD-K63277230	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66127
SSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78645
BRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08346
GSE168797_1_v_0_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE93674_2_v_3_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CCNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95316
aklomide	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04128
GSE188870,GSE188871_4_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K22875065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07458
TMEM35B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86378
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4223
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.2827
BRD-K69922285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46551
BRD-K81619018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3436
ZSCAN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92109
IFIH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31526
BRD-K30467307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.26733
B3GALT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22986
BRD-K51654114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00044
BRD-K89065802	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39042
GSE89154_1_v_3_proscillaridin_human	RummaGEO Drug Perturbation Signatures	1.0	null
FAM222B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43542
GSE157960_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF221	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38987
BRD-K31908823	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.69994
GSE113817_2_v_1_bach1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TRAK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05318
ZFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07081
BRD-K64264170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04386
GLCCI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58724
AA-80-XK94_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.39276
GSE153836_11_v_9_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NP5	DepMap CRISPR Gene Dependency	1.0	2.40107
NF-21-HQ00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.51652
BRD-K75067815	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.2721
C1orf116	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82576
ELOVL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15086
GSE143994_2_v_1_ythdf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RFX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.941
NOLC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81065
COX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47285
ZNF354C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35692
ZFP57	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3991
Autoimmune disease of musculoskeletal system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.888
BRD-K18783332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51139
PMC10534007-Table_2.xlsx-S3_unique_up_MSC_V-817_elements_included_exclusively_in_VM-CUB1_MSC_up_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN011_HEPG2_24H:A06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0022
CDK5RAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88943
SLC25A44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10241
GSE147056_2_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.58592
RBM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9902
AE-04-SN76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.390039
BRD-K90004516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30535
BRD-K18438502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36133
SPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26462
H3C8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6524
GSE210383_0_v_1_trim71_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Tonic - Clonic Seizures	DisGeNET Gene-Disease Associations	1.0	null
HSP90AA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33833
BE-73-KD75_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.474062
PMC12211354-12915_2025_2224_MOESM6_ESM.xlsx-Sheet1-Sheet1_The_source_list_of_zebrafish_Npas4b_targets_from_human_NPAS4_targets_in_CHEA3_database_NPAS4	Rummagene Transcription Factor Associations 2026	1.0	null
NFKB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5085
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7907
GSE199606_1_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MRM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67887
GSE120612_7_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NUDT15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91859
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.5023
BRD-K34335352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0374
SEPHS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54732
WM983B	DepMap CRISPR Gene Dependency	1.0	2.53047
CRCGN015_MCF10A.WT.HP_24H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.74804
AE-85-LR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.311993
CRCGN014_HEPG2_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.60475
BRD-K64704925	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79918
PARP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22462
KLF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8213
BRD-K83370434	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13709
GSE126345_2_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87314
ESCO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5642
debrisoquin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39644
PRDM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70192
BRD-K89853033	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53284
BTF3L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20399
GSE123022,GSE123030_2_v_0_trem2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7377
PRMT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05195
BRD-K63654001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12132
D502MG	DepMap CRISPR Gene Dependency	1.0	2.84744
GSE158834_2_v_9_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN009_HEPG2_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.49736
ZBTB17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34667
PMC7064337-elife-51373-supp1.xlsx-EZH2_targets_shPHF19-List_of_2084_genes_marked_by_EZH2_ChIPseq_after_PHF19_KD_shPHF19_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE153757,GSE153758_1_v_3_ftsj1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NUDT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58209
JPH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35736
BRD-K49207204	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89713
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-KLF6_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K88362336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.1489
ITPRIPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07869
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.2005
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
BECN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10751
GSE48812_3_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TMEM191B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16763
KIF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65913
BRD-K40266835	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.3343
GSE157555,GSE157556_4_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
YIPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08829
TBX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89185
BRD-K88988134	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54821
GSE146962_0_v_1_glucosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RALGPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61236
BRD-K66659401	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30744
AD-21-WS76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.204784
GSE214931_1_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FEM1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21144
FUT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71531
FAM171B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38803
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5575
EXOSC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27937
S100A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76555
HDDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7225
GSE248770_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8703
IDH3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12572
BRD-K90360779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2678
AGO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77238
UCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27677
VSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9895
PDCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42721
BRD-K30795375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17996
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6645
BRD-K90769476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.18832
RIPOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08263
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.888
SMIM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12479
PCMTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51827
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6976
Ascl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	46.5802
LRRC55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76515
TNP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48036
ARID3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95479
USP21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30845
PARD6G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44706
PGAM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98235
BRD-K41287744	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23799
MGAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36072
BRD-K60484506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21557
TMOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11651
GSE216273,GSE216292_0_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95759
ANKRD40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05385
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.149
BRD-K93624320	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7893
FHIP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29821
MACROH2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40591
KIF1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96801
ZKSCAN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2585
HC-74-HM63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.832837
PIGG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98229
NDFIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97368
GSE169571_0_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K30548577	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75349
BRD-K73402542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7061
PDLIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14445
BRD-K65829768	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25466
Alimentary canal	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K68953461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00816
BRD-K83010768	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26635
PMC7617064-EMS151900-supplement-Extended_Data_Figure_5_Source_Data.xlsx-CLC_D9_DEG-Logfold_change_threshold_1_0_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
CHST14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80115
BRD-K83786559	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31996
BRD-K22510845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33395
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HNF4A_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
SART3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14623
BRD-K90231936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7868
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.888
BRD-A80705936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13585
GPR153	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82721
ERV3-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34765
DENND4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57904
RAB2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46453
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
K029AX	DepMap CRISPR Gene Dependency	1.0	3.03775
HMGB1P1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3059
BRD-K22071228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73883
GSE233679_5_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE181959_1_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Yy1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.1338
Artery disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.8
C17orf97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40963
GSE217776,GSE217829_1_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K96265882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81687
BRD-K37790543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31173
BIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1554
GSE151829,GSE151831_1_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GC-04-UF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.905163
BRD-K55884477	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13989
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZGPAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37265
CRCGN016_MCF10A.TP53.M_24H:F11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.34136
FEZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73834
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3323
HDAC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03569
LRRN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28007
PMC10247733-41408_2023_863_MOESM4_ESM.pdf-574-ZSCAN1_ZSCAN1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE123002_0_v_1_srsf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
STAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29079
CHCHD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40937
PANC1	DepMap CRISPR Gene Dependency	1.0	2.16909
PGGT1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23757
PHF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09595
ZNF580	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.4706
TC205	DepMap CRISPR Gene Dependency	1.0	3.04997
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8766
DZIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.96722
FAM241B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33715
CRCGN015_HEPG2_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.91961
JF-14-JC89_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.272433
BRD-K86228587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.38913
AJM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83821
BRD-K33912919	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23175
EAST syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
CRCGN016_MCF10A.WT.HP_24H:D04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.4969
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXP4_FOXP4	Rummagene Transcription Factor Associations 2026	1.0	null
ENTPD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46569
GSE63048_11_v_8_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MST1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13356
BRD-K03715233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02065
TP53I3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.10307
PRADC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32698
GSE148252_0_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE109530,GSE109531_1_v_0_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CMBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41909
BRD-K87595216	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68589
GRPEL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96692
TSPYL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5839
BRD-K08408085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03146
RUBCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17434
BRD-K07959057	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.08756
CD200	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55404
ASMTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14155
PRDM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49608
Sensory ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.854
GSE84148,GSE96938_3_v_1_nrros_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K67096761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05703
BRD-K93817456	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7504
TXLNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67228
GSE129241_4_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
B4GALT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60826
BRD-K81246784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2307
BRD-K82056353	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.34878
BRD-K31390971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1407
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3899
ARIH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17187
BRD-K95927760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8044
BRD-K66708851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18675
GSE210476_9_v_8_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE130864_0_v_1_tincr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CCDC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14621
INSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39571
CRCGN010_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.84058
BRD-K97241181	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42972
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-TCF21_TCF21	Rummagene Transcription Factor Associations 2026	1.0	null
GSE123836_2_v_3_myf6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K32893898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41241
CHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06491
BRD-K54660148	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35808
AD-16-HL96_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.631339
ACCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44391
TBC1D3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45785
BET1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62185
RPL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19015
BRD-K25791914	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.79639
DNAJB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21101
MFSD6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05867
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3899
NASP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28812
PXMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14397
CNBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10236
PRMT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62194
HMG20A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64166
PHF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03024
KMS27	DepMap CRISPR Gene Dependency	1.0	2.26225
CAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77648
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7615
GSE229914_1_v_3_keap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K44779507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05184
CRCGN015_HEPG2_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.67
VMCUB1	DepMap CRISPR Gene Dependency	1.0	2.09276
XYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84754
FB-66-UU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.57958
MACF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53115
MROH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87035
SC5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44441
BRD-K93260425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58397
Amygdala	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
AP3S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87622
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.4757
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.1986
S0-EE-Y7IR_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.8878
RAG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2346
PRXL2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39772
S100A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37387
BE-57-VZ17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.206048
Type I spiral ganglion neuron_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
CRCGN008_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19575
ACAA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3539
RF-95-QO64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.247267
GSE142210_4_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
DNPEP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38313
ZNF222	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36253
MTDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8829
GSE68156_0_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K24743998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76236
BRD-K92644013	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.14314
BA-28-XM73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.353616
SNURF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98566
PMC6044387__F5	PFOCR Pathway Figure Associations 2024	1.0	null
GSE132759_4_v_2_fgfr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZBTB44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83191
GSE129241_3_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE131887_1_v_4_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K97938633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03324
OTX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51177
SYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22533
RGP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83904
CRCGN014_HEPG2_24H:D13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9756
CREBL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5563
BRD-K51163606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03363
GSE233679_6_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K39244231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60885
BRD-K71253424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24694
PRR19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75418
BRD-K64001802	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80718
BRD-K39131701	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05081
CRCGN014_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.97289
CCDC177	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11927
CDK11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72158
SCC9	DepMap CRISPR Gene Dependency	1.0	5.78551
INA6	DepMap CRISPR Gene Dependency	1.0	6.39492
BRD-K51515697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64081
MCF7	DepMap CRISPR Gene Dependency	1.0	2.03423
GSE131161_1_v_0_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.2144
POLR3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7035
BRD-K35527855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10041
Charcot-Marie-Tooth disease type 2E	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.163
DE-00-JU18_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.350519
BCLAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91938
GSE149903_0_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ATPSCKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8857
COA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86185
GSE199606_3_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RAB17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93004
WDR37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96508
SUSD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50538
CRCGN013_HEPG2_24H:K14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1414
BRD-K86911380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10306
MYT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89743
AGAP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57787
BRD-K95651150	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.13425
GSE216147_2_v_1_rbm20_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ACTR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60119
FYN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25731
BRD-K16937802	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.99738
SNX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34185
SKRC20	DepMap CRISPR Gene Dependency	1.0	2.85538
FSBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95183
PMC12178937-mmc6.xlsx-L_AKAP12_KDvsD_AKAP12_KD_deg_al-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
AMDHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10944
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.504
GSE123825_0_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K82968130	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38673
GSE124048,GSE124067_1_v_0_irf6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Combined deficiency of vitamin K-dependent clotting factors 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.57
APAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.57162
PGM2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47571
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-WT1_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF605	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18337
TFDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59695
KIAA1191	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27531
FBRSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82069
BRD-K58336011	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13579
GSE152699,GSE152723_3_v_2_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.47057
GSE157555,GSE157556_3_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:B23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.07191
SLC26A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65616
GTF2IRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19887
TOX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64595
BRD-K49507197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57358
BRD-K81751970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.20527
THBS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17429
GK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71186
GSE174418,GSE174421_0_v_1_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119498_0_v_5_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PITX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6605
ZNF728	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41212
BRD-K94855649	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70313
HOXB7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0146
OUMS23	DepMap CRISPR Gene Dependency	1.0	3.56659
BICDL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40513
BRD-K95147720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5275
ANKRD49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84696
PPARA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38089
CB-16-SY72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.8242
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9432
PMC10591879-NIHMS1933918-supplement-2.xlsx-Down_in_NMR_OPC_differentiation-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE145915_5_v_1_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain - Spinal cord (cervical c-1)	GTEx Tissue Gene Expression Profiles 2023	1.0	1.0407
GSE152699,GSE152723_0_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.0978
NFATC2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62147
CRCGN009_HEPG2_24H:A15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.11937
Birt-Hogg-Dube syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.488
WB-82-EL69_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.39849
CRCGN015_MCF10A_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.37925
GSE144919,GSE145177_1_v_0_dazl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.38577
ZNF234	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20234
GSE245134_2_v_3_atg5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210662_2_v_0_znf165_human	RummaGEO Gene Perturbation Signatures	1.0	null
NRARP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5292
BRD-K64732418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44456
GSE114992,GSE114993_7_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RSAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56885
NKX2-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12046
BRD-K92311828	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18962
GSE233679_5_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K50884475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62097
BRD-K98625375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02903
GSE210885_5_v_7_klf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE168797_1_v_5_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
RHBDF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49019
PMC8858874-NIHMS1764275-supplement-Supplemental_Table_2.xlsx-R1_SOX2_bound_genes_5000bp_6-9--Gene_Name_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.3116
FUZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14123
IRAK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12919
PPP2R5E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06543
BRD-K10528627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14451
OVOL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41461
H4C15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66766
GSE169205_3_v_2_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DUSP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78949
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.554
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.4225
TUHR14TKB	DepMap CRISPR Gene Dependency	1.0	3.00436
CRCGN009_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.3061
PMC7439574-13148_2020_914_MOESM2_ESM.xlsx-log2_fold_change_-2-1280_genes_are_more_than_four-fold_downregulated_in_PRDM8-_-_compared_to_control_PRDM8	Rummagene Transcription Factor Associations 2026	1.0	null
IDE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82469
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_12_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE125011_0_v_2_cd83_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K97327508	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24009
GSE211128_9_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9950457-mmc3.xlsx-GRHL2_overexpression_DOWN-gene_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
CE-18-AP15_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.324918
GSE210580_5_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE109285_3_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.42882
Satellite glial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.92
BRD-A54490075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31004
DOV13	DepMap CRISPR Gene Dependency	1.0	2.44865
BRD-K79997957	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00759
BRD-K92011556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02179
BRD-K18435317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20918
BRD-K58219783	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43192
ZNF418	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.95233
SSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92718
NCKIPSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64626
TRAPPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43495
ZNF775	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84153
C3orf52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66221
BRD-K01162126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06745
IA-76-ZU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.358602
MAT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51801
Myiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.265
USP48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57371
IRX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32525
Pigment granule membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.993
BD-18-MM33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.208941
GSE138633_2_v_0_bag3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K87080069	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.77639
TRAM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7268
GSE68156_0_v_1_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K36055854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1164
CCNY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07307
ATP6V0A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07681
BRD-K36644177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80586
BRD-K14925361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88409
ZDHHC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00998
BRD-K87264606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8181
GSE79663_2_v_0_tcf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K18000429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72333
FOXD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27199
GSE111660_1_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE115395_2_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
C6orf226	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27733
CRCGN014_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.47965
CRCGN009_HEPG2_24H:C08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01801
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7939
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3627
GSE111385_2_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K37760996	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09563
ZNF254	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50485
PAX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17526
KHDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33097
CLC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17059
HNRNPAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35582
H3C7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19464
BRD-K70154746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9699
BRD-K52001024	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08919
NIPSNAP3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85007
BRD-K09975370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.86115
PD-70-VS77_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.265197
rt1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.318
GSE151829,GSE151831_7_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CC-17-JL38_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.351383
RASD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65596
DAZAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63255
BRD-K82194980	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1978
ZSCAN31	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.3468
ACER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3475
SLC25A33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.207
BRD-K80736363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.26128
TRMU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55113
ZNF692	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96087
BRWD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66838
ZNF195	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60856
CDCA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87035
BRD-K53088255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81203
MTARC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92453
GSE219103,GSE219104_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE215351,GSE215794_4_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE180200,GSE180201_2_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NECAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11286
PIMREG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78559
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZNF473	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7009
PRELID3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11171
BRD-K34274486	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5949
BRD-K92974694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58018
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9768
INA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.087
BRD-K31407552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34485
FLVCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8669
BRD-K90127029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27853
GSE149903_5_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DGCR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56365
Musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.888
BRD-K51237617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28632
GSE119498_2_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211983_0_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K10820981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41645
Cervical carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K81608755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.55854
IC-05-AW29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.241143
KLF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21444
GSE186471_1_v_2_carnosol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE195559_0_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
VP229	DepMap CRISPR Gene Dependency	1.0	3.31927
MARK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04578
GSE210662_2_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE154337_0_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2063
CRCGN009_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13435
GSE128730_4_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE139016_3_v_2_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
C5orf22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88778
SPAG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60593
ATP6AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64522
PMC12224833-12967_2025_6787_MOESM3_ESM.xlsx-DEGs_PDX1-GeneSymbol_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
KB-45-CF78_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.25833
PLEKHO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92628
BRD-K69375224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28526
BRD-K97707303	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.38412
FIGLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65021
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1731
ACAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71111
BRD-A89554862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23737
PTPN18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29775
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-male_port-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K92700781	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.58689
GSE97278,GSE97280_2_v_1_nsd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CYB561	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84918
BRD-K37634338	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72439
GSE119345_2_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K94876980	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02909
VEGFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4993
GSE114685_1_v_0_grin2b_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K36368568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06093
DB-21-FY25_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.202136
BRD-K01045229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20789
ZNF467	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65467
SUZ12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41507
BET1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68098
SEC16A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97598
Stomach	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
FAM8A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87953
CRCGN013_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.32375
ZNHIT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76061
ZNF852	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84741
OGFOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14849
BRD-K31021810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54435
GSE214514_1_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Autoimmune disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.888
GSE186287_1_v_0_ufm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56684
ZNF468	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24236
BRD-K92655427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07683
CRCGN015_HEPG2_48H:J17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.38289
DPH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74511
CREBBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30069
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1692
BRD-K12077693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07853
KMT2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60722
BRD-K09108485	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20179
GSE137177_2_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K85633971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8406
MYCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25429
GSE171311_0_v_1_ellagic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
APIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73086
PMC10879698-mmc1.pdf-12-ZNF432_ZNF432	Rummagene Transcription Factor Associations 2026	1.0	null
ATAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44099
BRD-K08702524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61818
FB-66-UU47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.858031
BRD-K86746660	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76343
GSE197850_4_v_0_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
AC-97-KP88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.22489
Phelan-McDermid syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.108
BRD-K53343197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.04046
KDM4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7052
C12orf57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66389
BARD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72461
GSE210580_4_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KDM3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52728
GSE116354,GSE117379_2_v_4_cox2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SRSF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06007
GSE224294_4_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE101112_0_v_2_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SPIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71769
BRD-K48325920	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49315
REXO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70702
LACC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78201
TEF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70206
KNS60	DepMap CRISPR Gene Dependency	1.0	3.83479
TPM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86611
BRD-K58787433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.67831
ABHD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44663
GSE217363_4_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RETREG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51505
WBP1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80491
GSE88819_11_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1551
BRD-K23614490	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16564
GSE242199_9_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K11027431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91229
COQ6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9681
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.13982
PMC9564215-pnas.2203480119.sd02.xlsx-OVCAR-5_SCD_KD_cultured_in_low-hgnc_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
POU3F4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85117
NUDT16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57288
CCDC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58017
GSE100316_0_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K60886324	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58698
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.5176
KCNC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08389
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-combined_portrait-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
HFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70783
BRD-K62957665	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06241
BRD-K36096526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.193
NANOGNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45501
BRD-K70412800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04574
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.2191
BRD-K57251296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32218
GBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53243
BRD-K82217056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1785
GSE74490_0_v_1_triptolide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BE-79-QU25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.733039
MEF2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4705
BRD-K85357344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1247
BRD-K19652287	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69754
GSE160817_0_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE123825_0_v_3_glud1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN009_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.3115
BRD-K82064887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18922
CRCGN016_MCF10A.WT.HP_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.51347
RHOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97539
Bone disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.888
BRD-K20278539	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23232
NPAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21727
BRD-K01951210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27878
B800-820 antenna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.675
SMIM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6019
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-female_port-FOS_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K46742113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.14352
MFAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01212
BRD-K83752863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67925
CACNG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50749
BRD-K87658102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78524
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GIPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77349
SNRPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23243
BRD-K47784292	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.23796
BRD-K86938753	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0382
GSE145915_0_v_1_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K83108629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39157
GSE217363_0_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.80425
DEGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16841
BRD-K73427605	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28267
AA-16-HV95_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.202237
BRD-K75514760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58741
PMC12178937-mmc6.xlsx-L_AKAP12_KDvsD_AKAP12_KD_deg_al-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CRELD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15538
BRD-K04321001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01281
BRD-K19516614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47243
BRD-K10178088	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11166
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.436
TBK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13388
NUAK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24952
EIF2AK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07272
RBMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10183
SALL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85981
BRD-K18822985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73975
GSE154074_5_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF267	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47511
CEP43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43455
GA-88-CF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.780521
FLOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06219
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-HL-60-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_HL-60_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-SOX8_SOX8	Rummagene Transcription Factor Associations 2026	1.0	null
CDK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59776
BRD-K87748094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64322
RMDN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68678
APOBEC3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12656
CRCGN015_HEPG2_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.9866
RABL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00363
QE-79-XO29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.567035
QSOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.39351
GSE142232,GSE142234_0_v_3_gcgr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K66690073	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97994
CRCGN015_HEPG2_48H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.50941
BRD-K88645787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01331
GSE137325_2_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2313
BRD-K34234678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64227
PCBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39696
VCX3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7785
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.4847
GSE216273,GSE216292_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE133070_3_v_1_prss1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K71514806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25265
GSE119498_6_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.44215
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2882
TMEM52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46585
SLC46A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58285
PTPRJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6743
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8141
SNU349	DepMap CRISPR Gene Dependency	1.0	2.17708
WFIKKN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52593
NOS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69046
GSE88819_5_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE218060_2_v_6_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZBED1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.882
ECI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28756
AA-62-HP31_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.271991
CREB3L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97542
MEST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46957
CHST6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56766
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0371
CRCGN010_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.7567
CRCGN016_MCF10A.TP53.M_24H:O13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.09361
CRCGN015_HEPG2_48H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.74921
GSE90019,GSE90020_5_v_2_phf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE111247_14_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K68558540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.47418
CRCGN009_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.52716
BRD-K00530465	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49489
BRD-K86935536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16156
ISG20L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32056
CRCGN008_HEPG2_24H:K12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24678
ZSWIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57121
INPPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6858
CRCGN015_HEPG2_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.4261
SYAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02541
RAD23A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63294
CRCGN015_MCF10A_48H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.29897
CRCGN016_MCF10A.TP53.M_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.22088
BRD-K27849471	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48161
COL26A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51903
POLB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43409
PPP2R3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88784
HOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.188
GSE132948,GSE132949_0_v_5_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TRIM45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33994
MRPL30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55379
BRD-K16843478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38345
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6069
CHAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45976
Vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.8
HOXC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38131
BRD-K23503923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19058
SNU216	DepMap CRISPR Gene Dependency	1.0	3.05422
KE-37-MN32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.251841
TPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54361
GSE193588_3_v_2_pax3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7064337-elife-51373-supp1.xlsx-SUZ12_targets_shPHF19-List_of_567_genes_marked_by_SUZ12_ChIPseq_iafter_PHF19_KD_shPHF19_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K83898323	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.75026
OR2B6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85325
BRICD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04569
GSE116354,GSE117379_3_v_5_cox2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8373
CRCGN015_HEPG2_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.25745
PMC8185471-mmc4.xlsx-D4-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_4_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K72892670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51603
NCAPD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13215
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4958
ZNF573	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02291
TMEM249	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78058
BRD-K55069932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17485
BRD-K98935620	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19125
GSE181966_5_v_3_has2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SMARCA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26338
PRRG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73578
GSE158458_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF730	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0564
BTBD18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57444
ARRDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.446
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PDSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86605
GSE160373_8_v_2_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE65617_2_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K11662217	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.10027
GSE111660_1_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UBR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78125
BRD-K90697693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76247
BSPRY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82643
CRCGN015_HEPG2_48H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6464
TRAPPC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04592
BRD-K56759808	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48951
PMC8724844-bt-30-1-98-supple2.xlsx-GO_BP-SP1_SP1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE222758_0_v_2_clofazimine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Chitosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.922
H2BC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29002
GSE218580_1_v_5_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE80446_2_v_1_anakinra_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K17753780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86142
BRD-K21443215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08106
GSE114992,GSE114993_9_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142684_0_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BC-75-FA82_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.210263
BCL2L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58168
GSE226091,GSE226092_0_v_1_sall1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH1693	DepMap CRISPR Gene Dependency	1.0	2.08681
GSE188869,GSE188871_2_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE224547_1_v_0_cftr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K53893978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21112
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1053
d17	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.651
SPSB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07183
Nr1h3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.2579
SP140L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93414
ZNF446	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6404
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-male_port-EGR1_1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF90	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65849
BRD-K06029218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59855
GSE101239_3_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K40016301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.35597
BRD-K07489055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06917
PMC4595011-pgen.1005555.s003.xlsx-BPTF_UP-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
SPIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33099
ACOT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32172
GSE224096_3_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PPP1R3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62631
OPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53061
TMEM41A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04105
PCMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30697
BRD-K55940699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05436
GSE224294_3_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HIF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09506
CRCGN009_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.74993
GSE153354_0_v_1_tcf19_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE151829,GSE151831_3_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
BRD-K90092568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.421
CRCGN015_HEPG2_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.34715
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3901
BRD-K22715231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09995
GSE126345_4_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE120216_3_v_0_cbfb_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE221577_4_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MRPL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26721
BRD-K98505253	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70427
BRD-K95735171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22672
GSE210580_3_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3495
BRD-K93613839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.16417
BRD-K27406233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01457
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.888
TGFB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42271
RERFLCAD2	DepMap CRISPR Gene Dependency	1.0	4.49589
GSE221633_0_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	1.0	null
Limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN011_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.79735
GSE126345_7_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ANO9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37483
BRD-K92927161	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41353
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8174
ARL4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33912
AGAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63847
KIRREL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98426
BRD-K75724196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16174
TCEA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28581
BRD-K89264608	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39848
ERVV-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63292
BRD-K96106084	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.24205
DDX60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98238
BRD-K84391462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98689
BRD-K17718789	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23761
BRD-K10423475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05546
RF-36-EI47_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.255008
SLC19A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08714
ERP29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22333
DNAJC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41909
PLPP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46097
GMPPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74294
CDK5R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48759
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7445
XRCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60602
PMC12660214-Supplementaryfile1.xlsx-Genes_Human_with_ATF3-binding-sensory_perception_of_pain_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
MRPL17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6672
BRD-K36689392	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19492
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1557
METTL24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52162
BRD-K69238239	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06735
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6172
BRD-K94692455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25297
SBK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29397
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1875
CRCGN016_MCF10A.TP53.M_24H:C10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03653
SURF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33018
TMEM150A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40047
HCC1937	DepMap CRISPR Gene Dependency	1.0	2.34179
BRD-K61753872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58731
RAB3GAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88741
TRAPPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17918
BRD-K83751422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.15186
BRD-K93396907	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1737
CISH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75015
GSE196104,GSE196106_2_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RAB15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17886
BRD-K10798676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3204
SH2D5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6301
BRD-K06486611	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84089
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
DIRAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30832
BRD-K72083510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19802
BRD-K31377965	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02708
GSE214382,GSE214383_6_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3625
Hypertension and brachydactyly syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.44
BRD-K33953218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86984
ERLIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.90523
BRD-K96243955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38751
GSE160817_3_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
PIP4P1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7264
BRD-K92479346	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.60007
BRD-K94109423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09084
GSE151090_0_v_3_verteporfin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K79352289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96333
CLCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72177
BRD-K32751688	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71227
BRD-K05939258	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37116
VANGL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15859
THNSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32999
BRD-K35614154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22933
BRD-K69453385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22048
STK10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67991
POLE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16535
PIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68974
NP8	DepMap CRISPR Gene Dependency	1.0	4.76105
SETD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32074
DCAF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02689
BRD-K81181894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49653
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.285
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6885
CB-99-OG76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.50034
GSE200352_5_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142588_2_v_1_cinobufagin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CSTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19146
PMC10679653-mmc3.xlsx-ISL1_KO_Markers-Unnamed_0_ISL1	Rummagene Transcription Factor Associations 2026	1.0	null
ZE-45-CG69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.369822
BRD-K83673542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.232
CRCGN014_HEPG2_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.2841
RECQL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0363
BRD-K53356402	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03114
GSE158502,GSE158506_3_v_0_fat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K76713927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23736
GSE174406_2_v_0_lin28b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LCN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03545
HCC15	DepMap CRISPR Gene Dependency	1.0	3.51745
abnormal chemical nociception	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K82814367	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.999
GSE215086_0_v_1_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
COPS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16649
GSE93124_0_v_1_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DUS3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20478
BRD-K63919349	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03081
FAM72D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87484
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5087
DA-33-BM26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.686143
ALG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97493
preweaning lethality, incomplete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K97763545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40232
BRD-K80880605	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6738
ERP44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23484
CRCGN015_HEPG2_48H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4279
DYNC2I1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55305
GAS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77188
NDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47326
BRD-K66717300	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25022
GSE225735_1_v_4_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CBFA2T3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58171
IL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21692
synaptic vesicle membrane	SynGO Synaptic Gene Annotations	1.0	null
BRD-K81288338	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.8216
BRD-K46560430	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93193
GSE195559_8_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MICAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76119
BRD-K86358396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.2066
GA-88-CF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.10013
ZNF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6695
BRD-K94306568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4177
LYAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0653
Hereditary combined deficiency of vitamin K-dependent clotting factors	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.405
SELENOK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71166
TWNK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40519
FASTKD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20835
GSE208350_4_v_1_fgfr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K55939029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54708
NCKAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13261
BRD-K41707029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43919
GSE181589_2_v_0_spred1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K46348476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.17402
BRD-K92444813	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09567
RANBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70862
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0106
CD81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2023
KIF26A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1466
BRD-K69987634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31307
PMC9385264-NIHMS1828071-supplement-8.xlsx-AR-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PXYLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07376
DEPDC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92539
ISLR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78275
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2103
CHD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37094
FBXL19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83599
GSE68156_3_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SKI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56816
KRR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19883
LPP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7796
MTA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40789
RERFGC1B	DepMap CRISPR Gene Dependency	1.0	2.46852
BRD-K30491662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44732
ZNF722	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77897
CRCGN016_MCF10A.WT.HP_24H:O13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.64527
BRD-K85271599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10446
GSE160817_3_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205163,GSE205164_5_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.44825
BRD-K60932633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83494
CRCGN014_HEPG2_24H:B08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.50588
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0147
ZNF521	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81436
HLA-C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97213
GSE173810_0_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN013_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.93272
BRD-K41006887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51832
TOR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97292
CRCGN015_HEPG2_48H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.83199
GSE157383_3_v_2_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K73357010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00042
ABRACL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32966
GSE88819_3_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-combined_portrait-EGR1_1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
ZSCAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21747
PMC8858874-NIHMS1764275-supplement-Supplemental_Table_2.xlsx-R1_SOX2_bound_genes_5000bp_6-9--Nearest_Ensembl_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K74705119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33002
GSE249714_0_v_1_anxa1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K09248459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10208
BRD-K92570288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82733
Hypothalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.352
GPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80735