association	dataset	threshold value	standardized value
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cell projection membrane	GO Cellular Component Annotations 2015	1.0	null
inferolateral temporal cortex (area TEv, area 20)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.852353
PMC9558712-Data_Sheet_2.xlsx-POU3F4_WT_vs_CTRL-Unnamed_0_POU3F4	Rummagene Transcription Factor Associations 2026	1.0	null
ROS50	DepMap CRISPR Gene Dependency	1.0	5.00734
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.0002
GTEX-RN64-2326-SM-48FDW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986088
ovarian disease	GWASdb SNP-Disease Associations	1.0	0.393709
ACBD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13581
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.886
zr-75-30 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.47241
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4C9-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIGO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80519
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062589
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053153
GTEX-XBED-0003-SM-47JWP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.994135
GTEX-U8XE-0008-SM-4E3K4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23502
PIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66409
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48667
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.862184
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A5ES-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC52A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15578
ATIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56334
ZNF526	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41391
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Y-shaped link	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.241
transmembrane transport	GO Biological Process Annotations 2015	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A6E9-06A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.7969
PMC9643473-Table1.xls-MAF_0_005-HGVS_gene_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
core part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.42069
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.28675
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
rectum	HPA Tissue Protein Expression Profiles	1.0	1.03161
DRAM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63368
digestive/alimentary phenotype	MPO Gene-Phenotype Associations	1.0	null
DSH1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-O5YW-1526-SM-3MJGL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25261
mantle zone of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.3708
B3GNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7156
BL406 (RFC3)	NURSA Protein Complexes	1.0	null
situs inversus	MPO Gene-Phenotype Associations	1.0	null
Dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.699
SEPTIN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82285
Bile duct epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.786
Radial spoke	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.445
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.47644
calcium ion transport	GO Biological Process Annotations 2015	1.0	null
Simple lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17772
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28906
abnormal stomach morphology	MPO Gene-Phenotype Associations	1.0	null
PL-21	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NDUFA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36978
GSE233679_5_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-V955-0004-SM-3NMDH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49038
mantle zone of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10751
CEBPB_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A4/FUK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.994534
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TT-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE213588_9_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
COLO201	CCLE Cell Line Gene CNV Profiles	-1.0	-2.79639
GTEX-T2IS-0626-SM-32QP6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17639
pancreas	HPA Tissue Protein Expression Profiles	-1.0	-3.27633
plasma membrane part	GO Cellular Component Annotations 2015	1.0	null
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1616
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.13
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.942
PMC9235320-mmc2.xlsx-ST9_eQTL-MR-results-Unnamed_1_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P78B-0926-SM-2I5FA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03714
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.871243
blastomere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.090586
Pronephric duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.935
Flocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75505
GSE230263,GSE230265_3_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.120519
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.846713
GSE213588_10_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC4051124-1471-2164-15-256-S11.XLSX-WES_MSMD-STAT1-Target_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
Ciliopathies	WikiPathways Pathways 2024	1.0	null
primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.898468
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16087
NUDCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10865
HCC202	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ONS-76	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.7777
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IK-01A-32R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Joubert syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.622
GTEX-TML8-1426-SM-4DXUT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862276
MTHFSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93327
Ciliary basal body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.837
CAPN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39215
abnormality of sodium homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.85593
Dede	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.707
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.164
abnormal glucose homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.177776
GTEX-OHPL-0126-SM-2HMJ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51034
somite	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.539
orbital frontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23552
E4F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6959
BFTC-909	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_8922_KD_ARID1A_SRP192521	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.3985
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.315498
microtubule organizing center part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.386208
Perturb_14512_KO_HNRNPF_SRP296872	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.49745
mantle zone of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37079
RT11284	DepMap CRISPR Gene Dependency	1.0	3.00227
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-DY-A1DE-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-DY-A1DD-01A-21R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Meckel syndrome 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.232
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table5_gnomAD_SAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
Paramedian lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36055
IFNAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86172
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.959025
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUR-01A-21R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE233679_5_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Left_Ventricle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.36418
DPPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67047
BCOR-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MN-60	COSMIC Cell Line Gene Mutation Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.50756
left/right axis specification	GO Biological Process Annotations 2025	1.0	null
GTEX-NPJ8-0326-SM-2D7VV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877593
GSE200352_10_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EBNA2-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11756
HOXB7_01_170	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.22214
RASA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13344
striatum_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.46427
GSE125007,GSE125008_4_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.870586
BBX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13931
Uterus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.59947
Perturb_7136_KD_SETD8_DRP009168	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.05036
GSE143944_2_v_3_ribociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HNF4A_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05308
MED10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0735
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.148
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.908059
Cardiac tube	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.063
AN3-CA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Blastopore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.555
OV90	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45846
Duodenal atresia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.2
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-4502	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
NUDUL1	CCLE Cell Line Gene Expression Profiles	1.0	1.89289
BONNA-12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MRPL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32265
CDK7_knockdown_138_GSE31534	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.41796
GTEX-Q2AH-0008-SM-48U2J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05094
GTEX-RWS6-0008-SM-47JYV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63405
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00192
Lung adenocarcinoma_LUAD_TCGA-44-6778-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
kidney_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.850324
ALDH9A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57535
Ciliary inversin compartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.002
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.127
Congenitally Corrected Transposition Of The Great Arteries With Ventricular Septal Defect	DisGeNET Gene-Disease Associations	1.0	null
GSE94849_6_v_5_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
SDHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13892
JUN	ENCODE Transcription Factor Targets	1.0	null
orbital frontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23045
da1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.752
inorganic cation transmembrane transport	GO Biological Process Annotations 2015	1.0	null
PEO1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042685
HCC38	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34684
PSME4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3486
Floor plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.146
PTK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38169
DU 145	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05071
GTEX-T6MN-1526-SM-4DM5P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05677
ECC12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DPH7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49383
PMC12500934-41408_2025_1358_MOESM3_ESM.xlsx-Table_S6-DEGs_p_0_05_between_surviving_or_deceased_DLBCL_patients_that_received_R-CHOP_therapy_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
MAU2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70755
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3213
CAVIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15127
GSE127916_1_v_4_nras_human	RummaGEO Gene Perturbation Signatures	1.0	null
A172	COSMIC Cell Line Gene Mutation Profiles	1.0	null
organelle membrane	GO Cellular Component Annotations 2015	1.0	null
GTEX-WVLH-0226-SM-3MJG6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882141
hepg2	HPA Cell Line Gene Expression Profiles	-1.0	-1.15888
GSE207514,GSE207515_2_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BBSome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.64
DND-41	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE213442_1_v_0_kpna2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE217378_2_v_0_lin28b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H2347	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IBA57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01618
Perturb_7131_KD_SETD8_DRP009168	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.16033
MRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38458
CISH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75015
PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_10_CCF-Affected_Genes_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
NR1H4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34226
GCHFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3929
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H4C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1208
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.993621
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01982
hsa-miR-4653-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
integral component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.170629
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.0429
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00518
GTEX-V1D1-0003-SM-3NMDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884991
GTEX-TMZS-0001-SM-3P61Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22413
Stat5a::Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.6955
PMC12917211-Table1.xlsx-Table_S13-Table_S13_Gene-level_perturbation_statistics_from_the_virtual_KLF5_knockout_model_in_malignant_ductal_cells_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-548c-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
amygdaloid complex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.34131
IFFO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40232
8305C	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44499
CYYR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28541
u26684	HPA Cell Line Gene Expression Profiles	1.0	1.33256
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FM-8000-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNRF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14844
EBNA2-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08016
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A83P-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAFF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4UY-0006-SM-3K2A7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01088
GSE112760,GSE112767_4_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MRPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63443
JUN-26020271-SMOOTH-MUSCLE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZNF410	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.14693
Adrenocortical carcinoma_ACC_TCGA-OR-A5LH-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LNX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35106
KIF20A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55483
ZNF793	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27345
primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05346
GTEX-WH7G-0826-SM-4LVMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13073
GSE89154_1_v_3_proscillaridin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SMARCAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62258
paraventricular nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69231
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054599
HS294T	DepMap CRISPR Gene Dependency	1.0	2.25042
Cobalamin transport complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.82
SUB1_02_161	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.16993
CBX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02394
CSB-26484114-CHIP-SEQ-FIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H2AC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99869
tonsil	HPA Tissue Protein Expression Profiles	-1.0	-0.799465
Bounding membrane of organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11656
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.271093
hsa-miR-513b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61973
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.03461
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56928
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.984692
BSDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99994
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ESRRG_ESRRG	Rummagene Transcription Factor Associations 2026	1.0	null
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.931683
GTEX-RN64-0008-SM-48FEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.920835
Dorsal lip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.504
Sarcoma_SARC_TCGA-MO-A47P-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62597
Right_Ventricle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.16745
LKAAEAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52222
GTEX-S3XE-1526-SM-4AD5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22843
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.24653
GTEX-Q2AH-0126-SM-48U2B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01449
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PHAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28471
ACHN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNU245	CCLE Cell Line Gene Expression Profiles	1.0	1.34855
ALG10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82563
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.87197
GTEX-XOT4-1426-SM-4B65T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78346
GFOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36612
HO-1-N-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-Q2AH-0526-SM-2I3ED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14295
MFSD6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04194
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33703
Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7GZ-11A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE256181_1_v_0_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04317
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.03804
egg	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.150295
NCI-H508	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
hsa-miR-3545-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
PJA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30598
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7091-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TYK-NU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21154
GTEX-SN8G-0926-SM-4DM5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00972
cell projection membrane	GO Cellular Component Annotations 2025	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5834-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Transposition Of Great Vessels	DisGeNET Gene-Disease Associations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-MV-A51V-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10248509-Data_Sheet_6.CSV--GSE58294_DE-genes_AND_GSE22255_DE-Genes_NOT_Autophagy_NOT_GSE66724_DE-Genes_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
DMS-53	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_309_KD_YTHDF1_SRP256259	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.81337
DV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.54607
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.92025
ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
Perturb_14287_KD_TENT4A_SRP237261	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.40898
PRCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53395
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3596
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_12110_KD_MIR181A1HG_SRP337013	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.97697
GABRE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02719
ventrolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.964944
periventricular stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48287
CBX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87273
Lung adenocarcinoma_LUAD_TCGA-64-1681-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NPY1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05518
G-292_CLONE_A141B1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RALGAPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08539
periventricular stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.83587
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05557
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
CBX2	ENCODE Transcription Factor Targets	1.0	null
JSC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cytoplasmic dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.997
Acute Myeloid Leukemia_LAML_TCGA-AB-2882-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QDT8-0926-SM-32PL2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862678
HT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QEG5-0926-SM-2TC64	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54133
Kidney renal clear cell carcinoma_KIRC_TCGA-EU-5906-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autosomal dominant polycystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.679
Lung squamous cell carcinoma_LUSC_TCGA-O2-A52S-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
colon	HPA Tissue Protein Expression Profiles	1.0	1.03161
GSE109530,GSE109531_1_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Egg coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.843
FOS_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRMT10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84624
GTEX-UPK5-1326-SM-4IHLE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05291
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7389-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
smallintestine_4d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.13694
NCI-H1838	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_13496_KD_IGF2BP1_SRP252425	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Cyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.612
RAB40AL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.38029
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.961237
breast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.102672
647-V	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OHPL-1026-SM-3MJGI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.881237
ELP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22585
SLR25	CCLE Cell Line Gene Expression Profiles	-1.0	-1.74802
transporter complex	GO Cellular Component Annotations 2015	1.0	null
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29578
GSE148193_1_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
rostral secondary prosencephalon	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00647
S-117	COSMIC Cell Line Gene Mutation Profiles	1.0	null
internal granular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5294
GTEX-T6MN-0226-SM-32PMD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855495
placenta_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.2628
SOX2-21211035-LN229_GBM-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
mammary gland cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.442194
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
TCF21-26020271-SMOOTH-MUSCLE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MAP2K1_knockdown_134_GSE31534	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.02784
intermediate stratum of ITTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25198
PLAT/LH2 domain	InterPro Predicted Protein Domain Annotations	1.0	null
GATA3_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bile	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.927
periventricular stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18057
BB49-HNC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NKG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62527
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.44777
GSE77108_5_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.06494
PMC5895607-41388_2017_42_MOESM4_ESM.xls-geneNames-Extended_Data_3_Gene_list_of_SRC-1_targets_which_contain_STAT1_binding_motifs_from_LY2_cell_RNAseq_data_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.5587
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.872401
ACTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06893
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10272
PMC4595011-pgen.1005555.s003.xlsx-MITF_DOWN-regulated-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table6_gnomAD_EUR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NL3H-0008-SM-4E3HU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853923
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
premature ovarian failure	GWASdb SNP-Phenotype Associations	1.0	0.426693
Hepatitis C induced liver fibrosis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.552288
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.135
cellular process	GO Biological Process Annotations 2015	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.70175
CREB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8885
Subparaventricular zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.84446
leprosy	GAD Gene-Disease Associations	1.0	null
GTEX-RVPU-2226-SM-2XCAQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.890365
ADAM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23231
LRRC8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35802
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79621
Interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08254
r2 part of trigeminal sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14791
GTEX-O5YT-1326-SM-3MJGR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.927118
CAL 54	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57595
Dorsal peduncular area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6121
LDHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50161
PLEKHG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87973
hsa-miR-3119	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.969883
Stereocilium bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.444
HS746T	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65604
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.048468
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43548
Ependymal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.308
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
superficial stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48826
Polycystic kidney disease 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.248
STARD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63437
hsa-miR-4766-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GSE148200_3_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTNNB1-20460455-HCT116-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55G-0326-SM-48FDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.41322
mantle zone of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02169
GTEX-XLM4-0008-SM-4AT4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.964312
SNU-C1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05558
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table2_ChinaMAP_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XMK1-1126-SM-4IHJ8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958117
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.71652
Supplemental somatosensory area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83254
GTEX-TML8-0001-SM-3NMAF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08108
HNRNPD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84097
terminal subparaventricular area of THyA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.94027
UBXN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90122
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
left/right axis specification	GO Biological Process Annotations 2015	1.0	null
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10675
PMC3303130-NIHMS40463-supplement-4.xls-KamKwaMuk_AA_differences-human_geneID_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8332-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QDVJ-0226-SM-2I5FV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881762
Perturb_15588_KD_SOX9_SRP355992	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.54402
hsa-miR-4778-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
edema	MPO Gene-Phenotype Associations	1.0	null
layer 6 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08002
transmembrane transporter complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.008503
COV434	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.31786
Renal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.582
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.2975
NCI-H1703	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LK-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RU72-0008-SM-46MV8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.968944
NDRG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.03107
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4353-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE195559_2_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MPP-89	COSMIC Cell Line Gene Mutation Profiles	1.0	null
right-sided stomach	MPO Gene-Phenotype Associations	1.0	null
ECD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5192
ZC3H4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50421
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.41322
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7364-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM128	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79454
Crus 2, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43187
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.22519
single-organism transport	GO Biological Process Annotations 2015	1.0	null
GSE117212,GSE117214_0_v_1_zbtb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Rhox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.7937
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6939-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
TCF4	ChEA Transcription Factor Targets	1.0	null
KMRC1	DepMap CRISPR Gene Dependency	1.0	2.01124
GTEX-WL46-0926-SM-3LK7T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39295
NCI-H810	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44787
Ciliary shaft	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.583
RUNX1	ChEA Transcription Factor Targets	1.0	null
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.98336
Brain Lower Grade Glioma_LGG_TCGA-FG-6688-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0986
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16072
Thyroid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.828904
HLA-DOA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84828
Congenital heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.095
GSE139948_3_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SKOV3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52518
r2 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6466
POLR2A	ENCODE Transcription Factor Targets	1.0	null
mammary gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.167368
Asphyxiating thoracic dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.477
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054725
AMZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39091
GSE131887_5_v_3_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TIGD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75784
PC-14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Ciliary membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
TMEM175	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92331
germ layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064971
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.32433
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3496
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.18
GTEX-POYW-0726-SM-2XCEO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869482
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15891
ARIH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58828
KCL-22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Calcium channel complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29131
calcium ion transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.2425
inorganic cation transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
hippocampus	HPA Tissue Protein Expression Profiles	-1.0	-1.01516
ERF::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1774
NB10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH596	CCLE Cell Line Gene CNV Profiles	1.0	1.63762
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21955
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.864036
FXR	MotifMap Predicted Transcription Factor Targets	1.0	null
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.927744
TMEM35B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43221
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28114
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF616	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3066
GTEX-NL4W-0011-R8a-SM-2I3G4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03546
Declive (VI), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09655
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.32414
molecular_function	GO Molecular Function Annotations 2015	1.0	null
Primary visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11566
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12
Sarcoma_SARC_TCGA-PC-A5DN-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.914434
embryonic growth arrest	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-WY7C-0926-SM-3NB34	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27193
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3349-01A-01R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
embryogenesis phenotype	MPO Gene-Phenotype Associations	1.0	null
Perturb_14581_KO_NQO1_SRP217327	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.83917
Embryonic axis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.696
Renal tubule epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.742
GFY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88334
NCI-H2023	COSMIC Cell Line Gene Mutation Profiles	1.0	null
amyotrophic lateral sclerosis	GWASdb SNP-Phenotype Associations	1.0	0.832497
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.70175
ARHGAP19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82534
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062907
Situs Ambiguus	DisGeNET Gene-Disease Associations	1.0	null
TDRD3-21172665-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_18485_KD_CAV1_SRP251283	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.309
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13648
Polyhydramnios	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.954
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.47644
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-U3ZH-0002-SM-3NMDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32978
OV56	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10961
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4988-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NATD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78399
hsa-miR-1293	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
SLC25A45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92729
intermediate stratum of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06474
GTEX-XQ3S-0001-SM-4B64K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39653
MDAMB175VII	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.40471
496100439_PCx_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.25683
ABHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80006
GSE200352_10_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SYNDIG1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42982
Pulmonary vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.613
anterior pretectal nucleus, dorsal core part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06474
GTEX-SJXC-1226-SM-4DM78	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.948578
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09704
LYAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28026
chr7_47972695_TCCCCATTTGGGGTAGTATCCAGCACTAGGGTACTCACTGCACAGCG_T_b38	GTEx eQTL 2025	1.0	2.7649
SYAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.02541
BEND4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4728
upper respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.271886
LU-139	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10656
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PML	ENCODE Transcription Factor Targets	1.0	null
ZNF786	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41511
BT549	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.953919
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32506
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0844
LC-2-AD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hypertension	GWASdb SNP-Phenotype Associations	1.0	0.85593
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91124
posterobasal nucleus, intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21215
Perturb_310_KD_YTHDF1_SRP256259	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.31076
PMC10082806-42003_2023_4756_MOESM4_ESM.xlsx-AML2_RelvsTum_DMRs_anno-annot_symbol_RUNX3	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of r2Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19354
NCIH211	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39975
GTEX-PX3G-0226-SM-3NB2C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967492
Portal hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
TK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19881
GSE229309,GSE229314_4_v_1_elavl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SORT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2903
MMP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17802
r2 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.80618
thorax	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.09116
primary motor cortex (area M1, area 4)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.924637
Physical disorder	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
NCI-H1341	COSMIC Cell Line Gene Mutation Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Prostate adenocarcinoma_PRAD_TCGA-VP-A872-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MLLT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91003
BL8570 (MAP3K2)	NURSA Protein Complexes	1.0	null
RTBDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18558
Cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GSE136622_2_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TKQ1-0003-SM-3NMAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.982443
single organismal cell-cell adhesion	GO Biological Process Annotations 2015	1.0	null
MBLAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12417
RAB2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38721
male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.300894
SW620	COSMIC Cell Line Gene CNV Profiles	1.0	2.08334
GTEX-NPJ8-0426-SM-2HMK6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948657
Perturb_13946_KD_SAPCD2_SRP342327	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.794
retromammillary area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40839
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.04151
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2568
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04237
medial mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29167
r7 part of parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.96884
ROS-50	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09857
GTEX-X62O-0008-SM-46MU5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04063
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28518
cortex of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52049
Egg jelly receptor, REJ-like	InterPro Predicted Protein Domain Annotations	1.0	null
GTEX-XYKS-0002-SM-4BRWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.41322
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45932
GTEX-T8EM-1026-SM-3DB7M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.033
ADRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63127
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043922
GSE242083,GSE242098_2_v_1_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Perturb_18448_KD_PHF14_SRP199105	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
CTCF-21964334-BJAB-B-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
IGR-37	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.56293
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.69863
Primary visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11836
GSE123638,GSE123639_2_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE67266_2_v_4_etoposide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
LB373-MEL-D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898313
Atrioventricular septal defect	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.687
NR3C1	ChEA Transcription Factor Targets	1.0	null
MONO-MAC-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE169697,GSE169725_0_v_5_prrx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU1033	DepMap CRISPR Gene Dependency	1.0	3.43622
BID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18601
ANTXR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21695
Dorsomedial nucleus of the hypothalamus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08128
SW 1990	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0936
lateral ventricle	HPA Tissue Protein Expression Profiles	-1.0	-1.76538
ABI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29245
NCI-H510A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE213588_9_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4382-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.886644
dorsalstriatum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.30862
Rootlet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.763
oval paracentral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00258
HCC15	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51634
NFATC1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3378
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213588_10_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Intersegmental muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.733
SKM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.54607
hsa-miR-769-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
SIG-M5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.901124
hsa-miR-212	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.05128
GTEX-PSDG-0926-SM-2I5FP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00966
TMTC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73776
duodenum	HPA Tissue Protein Expression Profiles	1.0	1.03161
Acute Myeloid Leukemia_LAML_TCGA-AB-2887-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEP_3B2_1-7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8413-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1693	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cytoskeletal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.052679
GSE195663_0_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WCDI-0002-SM-3P61U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52549
Lung adenocarcinoma_LUAD_TCGA-44-7660-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05427
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.926208
pallidal amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1066
GTEX-XBEW-0002-SM-4AT5O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963648
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65876
r3 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.53182
non-motile cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
superficial stratum of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27691
dorsolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.934077
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE241701_2_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TE-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.08334
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.081
MAEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87154
membrane region	GO Cellular Component Annotations 2015	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.21197
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.849849
Sarcoma_SARC_TCGA-Z4-A9VC-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.999296
Pharyngeal cavity	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.514
Sarcoma_SARC_TCGA-DX-A6YU-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
testis_7e	HPA Tissue Sample Gene Expression Profiles	1.0	1.23541
PDZD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27929
QGP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.922498
HSPB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33072
TMEM37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34728
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12986
NOS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20071
ARF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4165
NUDT18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65701
20460173-ImmPortComprehensiveListofImmune-RelatedGenes	GeneSigDB Published Gene Signatures	1.0	null
GTEX-U8XE-0826-SM-4E3J1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17952
abnormality of the genitourinary system	GWASdb SNP-Phenotype Associations	1.0	0.049506
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21154
Centriolar satellite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.006
PKD/REJ-like protein	InterPro Predicted Protein Domain Annotations	1.0	null
GTEX-R55C-0008-SM-48FCF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62272
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05313
rostral paraventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59325
GSE247775_1_v_0_tmprss2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC50A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70242
FLO-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
response to endogenous stimulus	GO Biological Process Annotations 2015	1.0	null
Ciliary rootlet	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.014
GSE58724_3_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.81853
inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.862184
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.977321
breast cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.115208
624 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.8185
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.909911
hsa-miR-3148	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
LAN-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.814
NFIC	ENCODE Transcription Factor Targets	1.0	null
UMUC16	DepMap CRISPR Gene Dependency	1.0	3.55594
NIPBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80335
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69792
FARAGE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.39907
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2729
Flocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86219
Bed nuclei of the stria terminalis, anterior division, rhomboid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05876
divalent metal ion transport	GO Biological Process Annotations 2015	1.0	null
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF_Q1_vs_Q4-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
ventrolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.76935
Perturb_8493_KD_MBNL1_ERP115267	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.09796
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	3.24385
GTEX-OXRL-0326-SM-2I3F2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00893
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.879718
Brain Lower Grade Glioma_LGG_TCGA-CS-5396-01A-02R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.938033
STAT5A	ENCODE Transcription Factor Targets	1.0	null
GTEX-UPK5-2326-SM-3P5Z8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906558
Habenular trigone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.623
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.627
HS695T	CCLE Cell Line Gene CNV Profiles	1.0	1.59465
mammillary part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16798
BL2725 (SCAND1)	NURSA Protein Complexes	1.0	null
prenatal lethality	MPO Gene-Phenotype Associations	1.0	null
PLD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78855
blastodisc	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.190412
Orofaciodigital syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.543
GTEX-OXRK-1326-SM-3NB1A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.946675
lateral ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.993621
NCIH2087	CCLE Cell Line Gene Expression Profiles	1.0	1.49306
Esophageal atresia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.202
SSC4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22882
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36175
ZNF79	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20549
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V955-0326-SM-4JBGV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.41322
OSGEP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43253
TMEM185B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36667
superficial stratum of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36933
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05432
Nephronophthisis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.839
POLR3A_01_139	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.23074
GSS	DepMap CRISPR Gene Dependency	1.0	2.95361
GSE176008_4_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE161846,GSE161849_1_v_5_smarca4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4351-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE239844_7_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-NFK9-0926-SM-2HMJU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13504
ELAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61482
Sclerosing cholangitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.172
LXF-289	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55814
SU-DHL-16	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H64	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CAL27	CCLE Cell Line Gene CNV Profiles	1.0	1.47895
Ciliary pocket collar	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.864
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1AF-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r3 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.43351
Perturb_13886_KD_CDK4/CDK6_SRP258989	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.31
Pericentriolar material	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.867
GTEX-OOBJ-1026-SM-3NB2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.905419
GTEX-PLZ6-0526-SM-3P61C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.913948
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.43354
Anterior pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03095
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
abnormal gastrulation	MPO Gene-Phenotype Associations	1.0	null
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
superficial stratum of r1BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02457
COLO-678	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CSTF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69405
GSE195559_8_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PWOO-0008-SM-48TDU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966435
ME-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.39086
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7245-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cation channel activity	GO Molecular Function Annotations 2015	1.0	null
Superior colliculus, zonal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11483
Perturb_11687_KD_RRM2_SRP212736	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.43845
abnormality of nervous system morphology	GWASdb SNP-Phenotype Associations	1.0	0.085806
Calcium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.171
NCI-H2373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0531
r5 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11113
breast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.118378
GSE137954_4_v_2_smyd3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Visceral heterotaxy	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
Primary ciliary dyskinesia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.33
HS 695T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16203
DUSP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08819
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TB-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DESI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24091
CIDEA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24138
Perturb_13495_KD_IGF2BP1_SRP291710	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
embryonic growth retardation	MPO Gene-Phenotype Associations	1.0	null
Pharyngeal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.597
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02412
nb4	HPA Cell Line Gene Expression Profiles	-1.0	-1.15888
PMC8995879-Table_1.xlsx-exome_variants_MAF_0_01-Gencode_34_hugoSymbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
striatum_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.849783
CDPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67608
MBTPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45213
mantle zone of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37006
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54588
superficial stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28361
PROCR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16111
GTEX-UPK5-1126-SM-3GAEJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00854
A-673	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.08709
KYSE-70	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_18450_KD_H2AFJ_ERP124778	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.55036
MANSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00812
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.80037
Imperforate anus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.214
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2189
G-402	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.44249
Septin ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.538
496100355_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.33551
NH-12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Atrophy of testis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.305
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.945833
Nephronophthisis 11	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.107
testis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.459145
Integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
PMC11214527-mmc5.xlsx-NFATC3-gene_NFATC3	Rummagene Transcription Factor Associations 2026	1.0	null
PCDHB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.78445
GTEX-W5WG-1726-SM-4LMI5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872226
salivary gland	HPA Tissue Gene Expression Profiles	-1.0	-0.841185
Psoas_Muscle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.05807
GTEX-TKQ2-1826-SM-33HB2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.36319
metal ion transport	GO Biological Process Annotations 2015	1.0	null
posterior triangular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47921
detection of external stimulus	GO Biological Process Annotations 2015	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2847-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUP-HD1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OUMS-23	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.960044
Perturb_14536_KO_NTNG1_SRP278999	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.35351
Taste bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.58
VDR	ChEA Transcription Factor Targets	1.0	null
THBS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21487
ABCD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09711
fat_e	HPA Tissue Sample Gene Expression Profiles	1.0	0.982331
PL18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE77108_6_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intracranial hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.57655
GTEX-S33H-0126-SM-4AD62	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4979
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835616
RUNX3	ENCODE Transcription Factor Targets	1.0	null
GTEX-T5JC-0826-SM-32PMC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35053
NCIH2141	CCLE Cell Line Gene Expression Profiles	-1.0	-2.691
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TE4	CCLE Cell Line Gene CNV Profiles	1.0	2.26185
PMC3906982-1471-2164-14-830-S1.xlsx-Sheet1-Table_S1_HOXC9-responsive_genes_HOXC9	Rummagene Transcription Factor Associations 2026	1.0	null
P3HR1	CCLE Cell Line Gene Expression Profiles	1.0	1.43352
HS 69ST	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32843
GTEX-S7SE-0926-SM-2XCD6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961407
GSE233679_5_v_9_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
smallintestine_4a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.59201
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.305722
TXNL4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16932
GTEX-S33H-1126-SM-2XCB6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3105
GTEX-XXEK-0826-SM-4BRWG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42184
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.900491
Perturb_17180_OE_HER2_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-15.6244
NUP37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18627
layer 1 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08457
GSE216273,GSE216292_0_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.860088
BICR31	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SW 982	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.915748
left/right pattern formation	GO Biological Process Annotations 2023	1.0	null
PMC11184788-40164_2024_526_MOESM4_ESM.xls-MSC-EV_proteins-Unnamed_4_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
ciliary membrane	GO Cellular Component Annotations 2015	1.0	null
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1616
KLHL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86324
GTEX-SIU8-0326-SM-2XCDR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860026
r4 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13316
GTEX-S7SF-1426-SM-4AT5A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.986677
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13418
Lymphoma_burkitts(Daudi)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.867674
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XPVG-0926-SM-4B651	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24989
Olfactory areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14419
JUN_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
testis_7a	HPA Tissue Sample Gene Expression Profiles	1.0	0.853844
bounding membrane of organelle	GO Cellular Component Annotations 2025	1.0	null
roof plate of p2 (epithalamic roofplate)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51325
TRIM16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5669
RL95-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RM2N-0008-SM-48FF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35407
DHCR24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97267
superficial stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34008
TMEM14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64407
GTEX-XGQ4-2026-SM-4AT6G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38271
Tongue-capillary endothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	-9.007E-4
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
UBE2L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52111
GTEX-XBED-0526-SM-47JY3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00097
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067815
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
abnormal homeostasis	MPO Gene-Phenotype Associations	1.0	null
cilium	GO Cellular Component Annotations 2025	1.0	null
GSE158834_10_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WFON-2026-SM-4LVMW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38125
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30292
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Crus 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62963
NCI-H211	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LU-65	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.88
BL666 (BIRC6)	NURSA Protein Complexes	1.0	null
GTEX-VJYA-1326-SM-3GIJC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03591
HEB	MotifMap Predicted Transcription Factor Targets	1.0	null
NCIH747	CCLE Cell Line Gene CNV Profiles	1.0	1.64235
Polycystic liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.713
U031	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RNOR-0826-SM-2TF5C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75206
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36175
Polycystin cation channel, PKD1/PKD2	InterPro Predicted Protein Domain Annotations	1.0	null
Apical plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.222
EMC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50025
Ventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.28179
GTEX-WOFL-0726-SM-3MJG4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21206
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.986414
GTEX-SE5C-0326-SM-4BRWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832695
Geniculate group, ventral thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26185
GSE96641_1_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30687
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A3YO-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52306
Cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.92359
CDK4_knockdown_133_GSE31534	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.48815
C1orf54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00841
GSE58724_3_v_4_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Congenital chylothorax	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.501
Acute Myeloid Leukemia_LAML_TCGA-AB-2982-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Body wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.527
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16205
PMC12178937-mmc6.xlsx-L_MT1_KDvsD_MT1_KD_deg_all-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NUDT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68763
Plasma membrane bounded cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.27
GPKOW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03336
hsa-miR-495	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3107
GTEX-UJHI-0426-SM-3DB8Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35817
leydig cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.487106
Motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.516
NUBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81381
dorsal thalamus_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.839701
GTEX-U3ZN-0002-SM-3NMDF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67361
TSTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54739
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02603
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.831392
CTNNB1	ChEA Transcription Factor Targets	1.0	null
GTEX-RTLS-1326-SM-46MUN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26157
chr7_47937085_G_C_b38	GTEx eQTL 2025	1.0	3.0976
morphological abnormality of the central nervous system	GWASdb SNP-Phenotype Associations	1.0	0.097613
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10616
GTEX-PWN1-0226-SM-2S1OZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942154
DOV13	DepMap CRISPR Gene Dependency	1.0	6.28169
GTEX-WHSE-0926-SM-3NMBS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20167
MEIS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.77985
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27007
GTEX-OHPK-0326-SM-2HMJO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02472
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6093-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.41322
integral component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.138753
KYSE410	CCLE Cell Line Gene CNV Profiles	1.0	1.88032
abnormality of carbohydrate metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.1615
OLA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41588
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.833857
BCLAF1_02_142	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.24793
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MI-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Joubert syndrome 25	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.226
Joubert syndrome 24	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.235
GAK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bile ductule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.049
RELA_02_39	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.39232
abnormal left-right axis patterning	MGI Mouse Phenotype Associations 2023	1.0	null
SERPINE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41446
localization	GO Biological Process Annotations 2015	1.0	null
Choledochal cyst	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.441
Supramammillary nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39612
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.29064
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62558
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
male reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.277197
ARHGAP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94261
abnormal respiratory system morphology	MPO Gene-Phenotype Associations	1.0	null
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.00014
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5690-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2837-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACOT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32172
Primary visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13129
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3571
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE96777,GSE96778_1_v_0_zbtb4_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4595011-pgen.1005555.s003.xlsx-MITF_DOWN-regulated-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE214442_0_v_1_pak4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-875-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
WRNIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95055
GTEX-R55E-0826-SM-2TC5M	GTEx Tissue Sample Gene Expression Profiles	1.0	2.53874
vomeralnasalorgan.VMO.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.835149
H3K4me1_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-P78B-0526-SM-2I5F7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16958
Prostate adenocarcinoma_PRAD_TCGA-FC-A4JI-01A-11R-A250-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
calcium channel activity	GO Molecular Function Annotations 2023	1.0	null
shell part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41582
Congenital Atresia Of Pulmonary Artery	DisGeNET Gene-Disease Associations	1.0	null
GTEX-V955-0126-SM-4JBH5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.958091
adrenal gland	GTEx Tissue Gene Expression Profiles	-1.0	-0.952218
Lung adenocarcinoma_LUAD_TCGA-05-4422-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE60367_2_v_1_cxcr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pallister-Hall syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
ZNF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29687
Perturb_1686_OE_Mnx1_SRP373412	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE178227_1_v_2_tet1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Plasma membrane light-harvesting complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.533
NAMALWA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.24745
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.2924
MPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53764
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4789-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SC-596 (CCNA2)	NURSA Protein Complexes	1.0	null
GTEX-WL46-0126-SM-3TW8I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00556
Polycystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.774
GTEX-XMK1-0001-SM-4B64F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.912391
Lung squamous cell carcinoma_LUSC_TCGA-43-2576-01A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2BC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61778
Vena cava	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.158
Plant collar	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.562
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1212
GSE215351,GSE215794_2_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CA46	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE60837_0_v_3_bcl9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ITGA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97667
GSE138818_1_v_0_nanog_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
biological adhesion	GO Biological Process Annotations 2015	1.0	null
r6 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17959
Sarcoma_SARC_TCGA-DX-A3LS-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
external part of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00751
MZ7-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RM-01A-21R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_14375_KD_IGF2BP1_SRP291710	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.0949
Perturb_1096_KO_CIC_SRP230198	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.44181
COR-L32	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.72641
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.9441
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042743
Collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.555
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Heterotaxy	ClinVar Gene-Phenotype Associations 2025	1.0	null
heart disease	GWASdb SNP-Disease Associations	1.0	0.971735
P2RY11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59535
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.81135
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.41322
D-502MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-X4XX-0926-SM-46MV7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.974036
TRMT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.81873
HNT-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.14642
Prostate adenocarcinoma_PRAD_TCGA-YL-A9WH-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PCDHB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2615
cerebral cortex	HPA Tissue Protein Expression Profiles	-1.0	-1.33065
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.831044
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
Ciliary vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.548
calcium ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
ZSWIM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32433
GTEX-WY7C-0526-SM-3NB3D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10941
Neuromast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.035
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.970934
GTEX-SUCS-0326-SM-32PLL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933711
hsa-miR-3652	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
FOS	ENCODE Transcription Factor Targets	1.0	null
GSE226115,GSE226116_1_v_0_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51951
organelle	GO Cellular Component Annotations 2015	1.0	null
F36P	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54226
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4908-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13821
CDCA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50633
Prostate adenocarcinoma_PRAD_TCGA-HC-7209-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fasciola cinerea	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36933
GSE148200_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-Q2AI-1426-SM-2S1P5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00822
arl6	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.109
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CAOV3	DepMap CRISPR Gene Dependency	1.0	5.60099
periventricular stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11207
KYSE-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65269
Cholangitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.394
PYCR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.01503
GSE102505_6_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-67-3771-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
axis specification	GO Biological Process Annotations 2015	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A818-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal direction of embryo turning	MGI Mouse Phenotype Associations 2023	1.0	null
intermediate stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5559
ABRACL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32966
Cochlear nucleus, subpedunclular granular region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.27641
PGGT1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23757
GTEX-WRHU-0726-SM-3MJFL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910947
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.99917
posterior intralaminar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04365
response to stimulus	GO Biological Process Annotations 2015	1.0	null
Perturb_9570_KD_CDH11_SRP318732	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.18229
r5 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4817
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1709
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17603
hsa-miR-4687-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Thap11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	51.2242
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.408
channel activity	GO Molecular Function Annotations 2015	1.0	null
primary cilium	GO Cellular Component Annotations 2015	1.0	null
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.946784
GTEX-Q734-0126-SM-48U1E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.93998
Cystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.735
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6032
Cerebellum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12203
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1IC-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CPC-N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
JHH5	CCLE Cell Line Gene Expression Profiles	1.0	1.53898
lateral anterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81198
GTEX-U3ZM-1626-SM-4DXSK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41146
Ciliary membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.402
IGROV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.83322
NAV2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12748
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table4_gnomAD_EAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.837934
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.39554
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
BL9016 (SP3)	NURSA Protein Complexes	1.0	null
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XUYS-0226-SM-47JX1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76803
GTEX-Q734-0326-SM-48U15	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06773
Muscle-capillary endothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	3.05067
Anxiety disorder	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.51549
Retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.127
MBLAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78352
Somite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.768
SBK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20508
ion channel complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
breast cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.12428
Human - Fetal Development - L2 - Eye-Vascular endothelial cells	HuBMAP Azimuth Cell Type Annotations	1.0	null
Intestinal atresia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.14
dorsal part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43459
TGBC1TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-REY6-1226-SM-48FDR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.951301
Renal epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.496
9+2 motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.371
superficial stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5773
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98082
GTEX-VJWN-0126-SM-3GIK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.81234
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04613
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08268
hsa-miR-3663-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Lung adenocarcinoma_LUAD_TCGA-50-5936-11A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.337
Ventromedial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49278
IA-LM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_14535_KO_NTNG1_SRP278999	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.28751
USF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7738
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.0929
NOMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41362
GSE72895,GSE72896_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47788
terminal hypothalamus (rostral hypothalamus)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28328
blastula	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.094222
CACNB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18729
RAMOS-2G6-4C10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OOBJ-2126-SM-3NB1N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32257
Organelle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GTEX-QEG4-0426-SM-33HC3	GTEx Tissue Sample Gene Expression Profiles	1.0	2.40641
GSE238005_7_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PRMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98647
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4774-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ascending cholangitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.521
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A17X-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZR-75-30 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.791
Bronchial disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.002
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.76935
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.50741
GTEX-RUSQ-2026-SM-4GIAK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10342
mediodorsal nucleus of thalamus_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20844
HN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intermediate stratum of r10BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09191
GSE121198,GSE129782_1_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
single-organism localization	GO Biological Process Annotations 2015	1.0	null
layer 6 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07182
RPL22L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90004
MCC26	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ANKLE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11469
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
abnormality of ion homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.20811
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.857249
D-423MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Paramedian lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39317
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4974-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4342
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.4376
motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.01387
Declive (VI), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00115
PMC11214527-mmc5.xlsx-ADNP-gene_ADNP	Rummagene Transcription Factor Associations 2026	1.0	null
r8 part of inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42217
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23747
WM-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.846713
PMC9534852-41598_2022_20572_MOESM4_ESM.xlsx-Sheet1-Supplementary_Table_S4_Transcriptomic_data_related_to_AHR_function_considered_for_metabolic_reconstruction_model_generation_AHR	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH1299	CCLE Cell Line Gene CNV Profiles	-1.0	-2.07468
Duodenum Mucosa	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.29168
COLO829	CCLE Cell Line Gene Expression Profiles	-1.0	-1.84809
GSE213588_9_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_10311_KO_Dkk3_SRP067265	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.16388
GTEX-S32W-0626-SM-2XCBG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893153
Bed nuclei of the stria terminalis, anterior division, juxtacapsular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29035
HS 578T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.909207
Bardet-Biedl syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.813
PRMT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44346
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
organelle part	GO Cellular Component Annotations 2015	1.0	null
Intraciliary transport particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.636
NCI-H1770	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1876	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13923
NCI-H2444	COSMIC Cell Line Gene CNV Profiles	1.0	2.08334
GTEX-N7MS-2326-SM-2HMLD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09218
Perturb_8469_KD_BRG1_SRP048577	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
SEC61A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81406
GTEX-Q2AG-0226-SM-2S1P4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882854
SFXN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62874
inorganic ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
Biliary atresia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.498
NCI-H2452	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PWCY-2226-SM-2S1OP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30134
nonmotile primary cilium	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.6072
Cerebral degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.33
mantle zone of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93988
ARL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33745
ASPM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59561
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
detection of nodal flow	GO Biological Process Annotations 2015	1.0	null
Flocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95165
SUM159PT	DepMap CRISPR Gene Dependency	1.0	2.14062
Plasma membrane bounded cell projection cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.027
GTEX-SUCS-0008-SM-4DM53	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1795
plasma membrane region	GO Cellular Component Annotations 2015	1.0	null
diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.25112
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.60768
JHOM1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.89688
GTEX-SNOS-1126-SM-4DM67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63061
Paraflocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02918
C-33-A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Vestibular hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.501
TNPO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86957
FYN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51363
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16054
Neurula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.835
GSE77108_5_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A3/KAW	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.887428
USP33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97911
Anterior hypothalamic nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.49047
MROH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79293
k562	HPA Cell Line Gene Expression Profiles	-1.0	-1.15888
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42403
A-204 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.505
SNCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25335
NCI-H630	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MY-M12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_13953_OE_lncNR2F1_SRP179994	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.41717
GSE235587_2_v_1_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Ansiform lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65474
pattern specification process	GO Biological Process Annotations 2015	1.0	null
GTEX-WRHU-0326-SM-3MJFY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16206
GTEX-SJXC-0226-SM-2XCDU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04482
OV-17R	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cation channel complex	GO Cellular Component Annotations 2023	1.0	null
FMO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93081
B800-850 antenna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.785
KYSE-220	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PODXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22438
RNF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05223
POGLUT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6584
GTEX-P4PP-1026-SM-3NM9O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.87312
cilium	GO Cellular Component Annotations 2023	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A264-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NPM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79073
CEBPB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5507-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MFSD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11452
GTEX-WHPG-0626-SM-3NMBD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12788
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.1193
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
Chemoreceptor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.788
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.969883
BTBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33511
Refractive error	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.1
ae2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.609
ciliary membrane	GO Cellular Component Annotations 2025	1.0	null
NBEAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3675
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.07731
primary visual cortex (striate cortex, area V1/17)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.978013
MCF 10A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.20969
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.999296
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-POMQ-0326-SM-2I5FO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09727
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RHPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37257
Renal agenesis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.099
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02232
OVK-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
superficial stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.5699
Situs Inversus Totalis	DisGeNET Gene-Disease Associations	1.0	null
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39779
GSE216043_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
TNFRSF11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87197
PMC7780220-12943_2020_1301_MOESM8_ESM.xlsx-Fig_3A_RNA-seq_DEGs-Summary_701_LPS-induced_DEGs_361_THZ1-sensitive_DEGs_in_blue_of_macrophages_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE135352_0_v_1_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
atrophy/degeneration affecting the central nervous system	GWASdb SNP-Phenotype Associations	1.0	0.832497
GTEX-X4EP-0126-SM-3P5YV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.83137
OSC-20	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal cardiovascular system morphology	MPO Gene-Phenotype Associations	1.0	null
Lipase/lipooxygenase, PLAT/LH2	InterPro Predicted Protein Domain Annotations	1.0	null
GSE148200_0_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
sodium	GAD Gene-Disease Associations	1.0	null
GTEX-QVJO-1325-SM-2S1QX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829922
Lung squamous cell carcinoma_LUSC_TCGA-77-8153-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE242083,GSE242098_3_v_4_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.880079
transporter complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.008353
PARP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28448
KBTBD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60425
KDELR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61001
adipose tissue	HPA Tissue Gene Expression Profiles	1.0	1.4303
MALME3M	DepMap CRISPR Gene Dependency	1.0	3.84896
GTEX-WQUQ-1426-SM-3MJFD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37044
SMARCD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16564
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KMS27	CCLE Cell Line Gene Expression Profiles	1.0	2.37906
abnormality of female internal genitalia	GWASdb SNP-Phenotype Associations	1.0	0.13412
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70O-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCI-AML3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.31786
GTEX-SIU7-0001-SM-3NMAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940656
GTEX-UJMC-0226-SM-4IHLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.833569
GTEX-QVUS-0626-SM-447CC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.976717
GTEX-PX3G-0326-SM-2I3EO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52359
Perturb_2753_KD_WHSC1L1_ERP011490	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.72428
GTEX-WWYW-1326-SM-3NB2S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32957
Type 1 diabetes mellitus_T lymphocyte_GSE10586	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.52152
QGP-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Hypothalamic medial zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29304
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.849849
Inner medullary collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.9
KASUMI2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6713
central part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7023
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PO-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE85565_1_v_0_tcf21_human	RummaGEO Gene Perturbation Signatures	-1.0	null
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1IA-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.043859
terminal paraventricular area of THyA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37332
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3HZ-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFIC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEG4-0008-SM-48TYZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11939
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48076
mantle zone of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14811
RCM1	CCLE Cell Line Gene Expression Profiles	1.0	1.71894
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041585
TOPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45249
r2 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3279
GTEX-S7SF-2226-SM-3K2BG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36336
ICAM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28791
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.061001
detection of mechanical stimulus	GO Biological Process Annotations 2025	1.0	null
FAAP24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90451
FOXA1-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
Orbital area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10751
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76381
abnormal survival	MPO Gene-Phenotype Associations	1.0	null
Perturb_11915_KO_Rankl_SRP190820	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.42184
medial part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02004
GSE247764_0_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H650	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SF-0001-SM-3K2BE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0271
metal ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.12479
MFSD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36733
GTEX-X3Y1-0426-SM-3P5Z4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31242
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058287
PMC9038526-mmc1.xlsx-postCOVID_ctr_vs_LPS-symbols_98_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
SK-N-AS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.582
ARFGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10512
GTEX-RWSA-2026-SM-47JX8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10115
GSE58724_1_v_4_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SALL4-22934838-CD34+-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_5395_KD_LIM1_SRP402415	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.26085
NPRL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3863
disease	GWASdb SNP-Disease Associations	1.0	0.039056
GSE230263,GSE230265_6_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8494348-pone.0257161.s002.xlsx-only_D20_-_OXT_NOT_ext-Gene_Name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.868284
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.870651
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02952
cellular_component	GO Cellular Component Annotations 2015	1.0	null
RBM22_02_168	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.16993
Adolescent Idiopathic Scoliosis	DisGeNET Gene-Disease Associations	1.0	null
GTEX-Q2AG-0426-SM-2S1PU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833274
mantle zone of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16365
G142	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.34112
Kinocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.733
GTEX-WYJK-1026-SM-3NM8W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03966
SC-12738 (CSNK2A1)	NURSA Protein Complexes	1.0	null
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.947204
Situs inversus	ClinVar Gene-Phenotype Associations 2025	1.0	null
Perturb_17714_OE_MYOCD_SRP068760	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.20989
skeletal muscle	HPA Tissue Gene Expression Profiles	1.0	1.06077
GSE116894_1_v_0_tle3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-Q2AH-1626-SM-3GAF8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14036
C2CD4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.44748
mediodorsal nucleus of thalamus_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06176
postnatal lethality	MPO Gene-Phenotype Associations	1.0	null
GTEX-R55D-0126-SM-48FEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57402
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A8OW-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE145990_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
cell adhesion	GO Biological Process Annotations 2015	1.0	null
carbohydrate metabolism disease	GWASdb SNP-Disease Associations	1.0	0.230182
Crus 1, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60579
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00751
cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.905695
H1-0	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42721
KMRC3	CCLE Cell Line Gene Expression Profiles	-1.0	-1.76726
hsa-miR-4288	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
NUP88	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16939
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.18613
right-sided isomerism	MPO Gene-Phenotype Associations	1.0	null
EIF4EBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78116
GTEX-XPT6-2226-SM-4B66R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32263
cilium	GO Cellular Component Annotations 2015	1.0	null
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05427
GSE121857_2_v_1_sin3b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.960497
Mastigoneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.76
kidney_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.41064
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
KLC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28202
DCPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72681
hsa-miR-4539	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
PLEKHG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57965
YT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Hydrolethalus syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.153
GSE134029_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34583
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.40297
hsa-miR-515-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
MEL-HO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-H4-A2HO-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZG-0326-SM-47JXN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923243
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.32852
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	3.49576
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.989019
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15757
primary cilium	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
NCI-H345	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-1229	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27007
Platelet dense tubular network	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.041
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.849741
Cell projection membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.86749
artery disease	GWASdb SNP-Disease Associations	1.0	0.134138
GTEX-QLQW-0226-SM-447BJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66531
abnormality of cation homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.20811
bounding membrane of organelle	GO Cellular Component Annotations 2015	1.0	null
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19322
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.06046
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A5KF-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A820-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MRK-NU-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QEL4-0926-SM-3GAD1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.928776
ZNF836	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01916
GSE162015_2_v_0_nfkb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE233679_5_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MT-CO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65857
NR3C1-21868756-MCF10A-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CAL-120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.61736
Prostate adenocarcinoma_PRAD_TCGA-CH-5769-11A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHUEM3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57001
MRPL53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50691
Outer dynein arm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.724
cerebellar cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.98609
GTEX-XQ3S-1326-SM-4BOPQ	GTEx Tissue Sample Gene Expression Profiles	1.0	3.11086
GSE106661,GSE106665_2_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
orbital frontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05583
Plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GTEX-OXRP-0226-SM-3NB14	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4021
Lung squamous cell carcinoma_LUSC_TCGA-43-7657-01A-31R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74966
Intraciliary transport particle A	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.684
YBX3_02_153	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.0
SPPL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38771
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.792777
dorsolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.952916
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.951321
right-sided stomach	MGI Mouse Phenotype Associations 2023	1.0	null
GSE223008_9_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cilium	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.36177
Double outlet right ventricle	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.924
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.909911
GTEX-PVOW-0426-SM-2XCF8	GTEx Tissue Sample Gene Expression Profiles	1.0	2.29721
TSEN15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22483
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.41322
ASXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23051
GTEX-XPT6-1626-SM-4B655	GTEx Tissue Sample Gene Expression Profiles	1.0	0.998581
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-REY6-1026-SM-2TF4Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14884
GTEX-OIZI-0005-SM-2XCED	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43257
Dorsal part of the lateral geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2966
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26377
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A3Z3-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21431
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29165
Centriole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.635
RAB43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01686
RCBTB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49272
SLC39A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03733
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.931683
GSE120370_4_v_3_thrombin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77389
Rectum adenocarcinoma_READ_TCGA-DC-6154-01A-31R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_12222_KD_FOXA1_SRP267080	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.066793
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
r1 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39415
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.784
TTC9C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25972
r6 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01616
AGS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.994708
COLO677	CCLE Cell Line Gene Expression Profiles	1.0	2.00381
hippocampus (hippocampal formation)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.93975
P300-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H2110	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EFO-21	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSDMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17401
PMC10534007-Table_2.xlsx-S6_unique_down_MSC_B-914_elements_included_exclusively_in_BFTC905_MSC_down_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.13183
layer 6 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19646
FOXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5615
Ciliary tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.877
GSE162015_1_v_0_nfkb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PLK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43269
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4961-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HTR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58825
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.41322
MDA-MB-415	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-Q734-0426-SM-48TZX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60919
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.485292
periventricular stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6466
600MPE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.70941
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SYCE1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16282
abnormality of metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.078959
Right Aortic Arch (Disorder)	DisGeNET Gene-Disease Associations	1.0	null
GSE123638,GSE123639_3_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE187006_0_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
SALL4-22934838-CD34+-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
DEL	CCLE Cell Line Gene Expression Profiles	1.0	1.51304
autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.714005
non-motile cilium	GO Cellular Component Annotations 2025	1.0	null
Cytoplasmic region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.707
SNU466	CCLE Cell Line Gene CNV Profiles	1.0	1.51826
SLC17A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45532
GTEX-WHWD-0426-SM-3LK83	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34795
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.91932
T47D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Yy1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.7863
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.06729
response to abiotic stimulus	GO Biological Process Annotations 2015	1.0	null
GTEX-SSA3-0326-SM-32QPS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01015
GTEX-TKQ2-1226-SM-4DXSV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2938
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
LPAR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17642
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.224398
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7595-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTNNB1-20460455-HCT116-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HM7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.27798
GTEX-R55C-1826-SM-3GADI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.882007
abnormality of cardiovascular system physiology	GWASdb SNP-Phenotype Associations	1.0	0.099256
BPH-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
heart muscle	HPA Tissue Gene Expression Profiles	1.0	0.926331
GTEX-RNOR-1326-SM-48FDE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06795
BE2-M17	COSMIC Cell Line Gene Mutation Profiles	1.0	null
visceral heterotaxy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.03409
PRECLH	CCLE Cell Line Gene Expression Profiles	-1.0	-2.56781
amygdaloid complex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.885977
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040948
a549	HPA Cell Line Gene Expression Profiles	1.0	0.878894
TC-71	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.66166
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.3186
testis_7d	HPA Tissue Sample Gene Expression Profiles	1.0	2.20476
MEL-JUSO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06176
GSE131887_5_v_2_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.849849
Autosomal recessive polycystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.701
GTEX-RUSQ-0526-SM-2TF72	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07455
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.855369
Pancreatic_Islets	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.857344
GSE236437_0_v_3_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Mesothelioma_MESO_TCGA-TS-A7OY-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YKG-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SMARCB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56995
MKS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.471
single organism cell adhesion	GO Biological Process Annotations 2015	1.0	null
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.986
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.282
ZNF346	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30475
MYH14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44772
cerebellar cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13923
substrate-specific transporter activity	GO Molecular Function Annotations 2015	1.0	null
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
B4GALT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8542
TDRD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57512
non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.325
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31941
GTEX-VUSG-1526-SM-4KKZH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.871662
UACC812	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.23627
CKLF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08418
embryonic growth arrest	MPO Gene-Phenotype Associations	1.0	null
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64427
Microvillus inclusion disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
PACSIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54005
adrenal_4c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.861876
central nervous system disease	GWASdb SNP-Disease Associations	1.0	0.119475
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.052025
passive transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
GSE106661,GSE106665_0_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
KLF5-20875108-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Diastolic blood pressure response to hydrochlorothiazide in hypertension	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.552288
PLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1474
dorsolateral prefrontal cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.72848
OCILY10	CCLE Cell Line Gene Expression Profiles	1.0	1.81678
MT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34936
TNFAIP8L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39028
ELF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.5191
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1616
PTBP1_02_131	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.08746
adipose tissue	GTEx Tissue Gene Expression Profiles	1.0	0.940917
VDR-23401126-LCL-AND-THP1-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.60146
ZNF33A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19421
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.9299
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6960-01A-41R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45492
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19977
MDM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10934
GTEX-TKQ2-0226-SM-4DM6V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860325
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3ZF-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TE-4	COSMIC Cell Line Gene CNV Profiles	1.0	2.08334
Inferior vena cava	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.972
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.23817
Cerebellar cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13961
IMCD cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.657
response to mechanical stimulus	GO Biological Process Annotations 2015	1.0	null
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23998
Adrenocortical carcinoma_ACC_TCGA-OR-A5JO-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRK-1626-SM-3NB17	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10715
COX4I1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99012
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.0336
MITF	ChEA Transcription Factor Targets	1.0	null
LOU-NH91	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0821
GSE217115_3_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GABPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1117
SW48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QEG4-1226-SM-2S1P6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.992752
cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36342
GSE77108_3_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-548o	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.71512
PMC4595011-pgen.1005555.s001.xlsx-MITF_DOWN-regulated-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal stomach position or orientation	MPO Gene-Phenotype Associations	1.0	null
Cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.679
GATA2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SU-DHL-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE247764_5_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XV7Q-0826-SM-4BRV7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.9122
transport	GO Biological Process Annotations 2015	1.0	null
GTEX-RU72-0326-SM-2TF5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26335
HNRNPLL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21709
lower dorsal perifornical nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78213
intermediate stratum of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.57934
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91605
Sperm flagellum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.471
Prostate adenocarcinoma_PRAD_TCGA-CH-5789-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW620	CCLE Cell Line Gene CNV Profiles	1.0	2.39824
A172	DepMap CRISPR Gene Dependency	1.0	2.20409
ECSIT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02351
polycystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.26996
GTEX-PSDG-0008-SM-48TE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.007
NCI-H2722	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.83539
NFATC1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06542
GSE233679_6_v_4_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.1097
Rectum adenocarcinoma_READ_TCGA-CI-6620-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
calcium channel complex	GO Cellular Component Annotations 2023	1.0	null
Ciliary plasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.08
MITF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2537
GLIS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64212
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.99335
Perturb_4875_OE_HAND1_SRP216437	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
PPP1R15A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33463
detection of endogenous stimulus	GO Biological Process Annotations 2015	1.0	null
CMK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5KX-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE187006_0_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
RAB3GAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01231
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95463
GTEX-OXRO-0326-SM-33HBM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949998
GTEX-RN64-1026-SM-48FDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.939447
binding	GO Molecular Function Annotations 2015	1.0	null
abnormal genital system morphology	GWASdb SNP-Phenotype Associations	1.0	0.086317
Lung adenocarcinoma_LUAD_TCGA-55-1592-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ENDOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34736
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCT-116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.9262
KYSE-410	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3JW-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60287
Biliary epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.241
Nephronophthisis 14	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.222
GTEX-T5JC-0001-SM-3NMAK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89078
PMC6167382-41467_2018_6258_MOESM4_ESM.xlsx-TEAD-associated_GSC-Specific_UP-Nearest_Ensembl_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OHPN-0008-SM-4E3HW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11334
Venous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.896
LIM1215	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Hemispheric regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59852
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.5335
single-organism process	GO Biological Process Annotations 2015	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.40867
GSE247764_1_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30029
PNPLA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38109
EN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63786
GTEX-WK11-2426-SM-3NMAA	GTEx Tissue Sample Gene Expression Profiles	1.0	3.05272
prepontine hindbrain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07911
t47d	HPA Cell Line Gene Expression Profiles	1.0	1.47666
heart	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.28213
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7546
r5 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33822
PMC4595011-pgen.1005555.s001.xlsx-BPTF_DOWN-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
SK-OV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.49645
Lung squamous cell carcinoma_LUSC_TCGA-56-8309-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33215
NFIC::TLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.625
Perturb_234_KD_MITF_SRP048577	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-15.8955
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7826
periventricular stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32875
AKT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86097
GSE247764_3_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Adrenocortical carcinoma_ACC_TCGA-PK-A5HB-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-6744-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU869	CCLE Cell Line Gene CNV Profiles	-1.0	-2.7003
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056204
DRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22621
cell projection part	GO Cellular Component Annotations 2015	1.0	null
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051664
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.41322
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.57288
hsa-miR-513a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67W-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-A5EL-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amyotrophic lateral sclerosis	GWASdb SNP-Disease Associations	1.0	0.945129
GTEX-NFK9-1126-SM-3LK78	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.41322
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.86876
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A411-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9714459-DataSheet3.xlsx-Supplement_3A-1037_elements_included_exclusively_in_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV7-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4347-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
monoatomic cation channel activity	GO Molecular Function Annotations 2023	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4904-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE242083,GSE242098_2_v_4_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
NFRKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44868
AURKC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3241
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.839701
endometrium	HPA Tissue Protein Expression Profiles	-1.0	-1.01516
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058634
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054274
GSE166315_2_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MED15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11573
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31387
PMC6713698-109_2019_1809_MOESM2_ESM.xlsx-AR-PCOS-Gene_List_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-UPK5-0226-SM-3GAEV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07001
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831293
G-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GDF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28767
GTEX-QEG4-0526-SM-48TZD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08625
Dextrocardia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.272
GTEX-PVOW-1026-SM-2XCF9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77148
PTK7_knockdown_185_GSE50138	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.74098
TTLL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9329
primary motor cortex (area M1, area 4)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.65887
adrenal gland	HPA Tissue Gene Expression Profiles	-1.0	-1.04488
GSE189834,GSE189836_1_v_0_brd4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19987
CCRF-CEM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mantle zone of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.53182
pancreas_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12216
GTEX-T8EM-0526-SM-4DM64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17403
SDHC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91076
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.981465
GTEX-U3ZG-0001-SM-47JYF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.41322
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.93975
PMC11385078-jciinsight-9-172336-s272.xlsx-1DEseq2_Report_AA_BL_vs_EA_BL-Unnamed_1_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
COL9A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42551
superficial stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8083
PSMG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27804
GSE226285_3_v_0_nr0b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.35904
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29L-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE234289_3_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
r7 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19833
terminal nucleus of the stria medullaris	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08221
Perturb_14631_KD_MSI1/MSI2_SRP067129	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.96483
Double Outlet Right Ventricle	DisGeNET Gene-Disease Associations	1.0	null
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.973974
SUDHL10	DepMap CRISPR Gene Dependency	1.0	2.17618
Perturb_2393_KD_HIF1A/HIF2A_SRP308699	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.16892
Lung adenocarcinoma_LUAD_TCGA-55-8096-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.182
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR2C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0299
TLNRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37838
PABPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93199
intermediate stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69594
PMC11133462-41467_2024_47218_MOESM5_ESM.xlsx-IL-10_SBNO2_KD-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SBC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OCI-AML5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.350001
periventricular stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2249
PMC6137307-mmc2.xlsx-STAT2-IFNa-Table_S1_STAT2-IFNa_Related_to_Figures_1_4_STAT2	Rummagene Transcription Factor Associations 2026	1.0	null
orbital frontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.47644
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68307
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
UKE-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.67506
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5552-01B-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.934077
POMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42073
Bronchiectasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.494
TE-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.127227
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.445
ENOPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72579
Heart - Left Ventricle	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.836646
P53-21459846-SAOS-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SLC20A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23619
r9 part of nucleus gracilis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13052
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
r10 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26568
GTEX-O5YT-0326-SM-32PKA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31897
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50569
CCDC96	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.26992
NCI-H1436	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MCAS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.999296
MTA3	ENCODE Transcription Factor Targets	1.0	null
calcium channel activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68776
suprachiasmatic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.59294
PMC7818749-12931_2021_1617_MOESM1_ESM.xlsx-TBX4-SYMBOL_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
APP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63123
TT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CAL-148	COSMIC Cell Line Gene Mutation Profiles	1.0	null
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-0.841185
SUDHL4	DepMap CRISPR Gene Dependency	1.0	2.83155
L-428	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XBEC-1326-SM-4AT69	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06439
SNF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09243
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29264
paraventricular nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10746
superficial stratum of RtC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25254
GTEX-QEL4-1226-SM-447A4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0231
GTEX-WFG7-0426-SM-4LMK5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11636
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.1479
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.5586
OSC-20	COSMIC Cell Line Gene CNV Profiles	1.0	2.08334
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.97819
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00151
developmental process	GO Biological Process Annotations 2015	1.0	null
appendix	HPA Tissue Protein Expression Profiles	-1.0	-1.01516
PPTC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62847
PMC9643473-Table1.xls-MAF_0_005-Gene_refGeneWithVer_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
METTL22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31027
GSE84462,GSE84762_0_v_7_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
testis_7b	HPA Tissue Sample Gene Expression Profiles	1.0	1.3405
GTEX-Q2AI-0008-SM-48U2H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889365
rostral interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06976
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0002
FADU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SC-7898 (CHEK1)	NURSA Protein Complexes	1.0	null
abnormal prenatal growth/weight/body size	MPO Gene-Phenotype Associations	1.0	null
ERO1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05218
GTEX-T5JC-0226-SM-32PMA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04201
establishment of localization	GO Biological Process Annotations 2015	1.0	null
GTEX-QDVJ-0426-SM-2I5FW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87858
K2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SLC16A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50759
r3 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.135
SUB1_02_117	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.08746
CDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16047
Alagille syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.86
ACAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36519
P68-20966046-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CADO-ES1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RVPU-0011-R1A-SM-2XCAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.941731
ACHN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.79608
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-0.841185
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.34902
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4905-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE233679_6_v_2_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.64811
ASCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21263
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.70065
hsa-miR-1323	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.023
P12-ICHIKAWA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PLZ5-1526-SM-3P5ZX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1386
adrenal gland	HPA Tissue Protein Expression Profiles	1.0	1.03161
GSE169205_0_v_1_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
mantle zone of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36342
snoutepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.884245
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
cation channel complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
MDAMB175VII	CCLE Cell Line Gene Expression Profiles	1.0	3.40796
EW-12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
NCI-H2087	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Neural tube defect	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.228
HNRNPH1_02_08	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.64386
autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.779841
Cranioectodermal dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.037
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.93824
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUU-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WK11-0626-SM-3NMAV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825577
GSE77108_3_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.858
TGW	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
WM115	CCLE Cell Line Gene CNV Profiles	1.0	1.41061
NAGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.98583
GSE93309_5_v_3_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.87623
ventrolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.997007
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.2957
Sinusitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.299
superficial stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.96884
GSE137177_1_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PAK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.00565
OV56	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.92776
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01368
GTEX-QDVN-0326-SM-2I3FS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883682
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.71425
GSE94849_3_v_5_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCC010	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-R55E-1026-SM-2TC5S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73129
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.13427
HSD11B1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0799
Dubin-Johnson syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.184
detection of mechanical stimulus	GO Biological Process Annotations 2023	1.0	null
SUP-B15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.08709
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.13527
CAL-54	COSMIC Cell Line Gene CNV Profiles	1.0	2.08334
KARPAS-231	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Simple lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17301
dorsolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.940605
WAPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83765
Ciliary transition zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.464
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SRM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5487
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.962663
ERI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02396
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874618
Retinal rod	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.799
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.988212
SNU869	CCLE Cell Line Gene Expression Profiles	-1.0	-1.95895
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.9919
GNG14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98317
r7 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3813
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.13738
ciliary part	GO Cellular Component Annotations 2015	1.0	null
abnormal left-right axis patterning	MPO Gene-Phenotype Associations	1.0	null
IRX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24516
HPAC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Perturb_15108_KD_MPP8_SRP218207	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.47615
Retrochiasmatic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.48565
Claustrum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08097
male infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.439786
NPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3391
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-7130-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rhombomere 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01834
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.39086
SEM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61515
Primary localized cutaneous amyloidosis 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.082
p3 portion of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07784
hsa-miR-1290	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Lung squamous cell carcinoma_LUSC_TCGA-77-6842-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAL-85-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-U412-0526-SM-3DB9I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11513
primary ciliary dyskinesia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.04293
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72528
abnormal left lung morphology	MPO Gene-Phenotype Associations	1.0	null
GSE120370_0_v_3_thrombin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H2461	COSMIC Cell Line Gene CNV Profiles	1.0	2.08334
Adrenocortical carcinoma_ACC_TCGA-OR-A5LO-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral posterior nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55626
GTEX-QEL4-1326-SM-447AD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07019
HELA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.872848
DSTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5081
GTEX-N7MS-0326-SM-4E3K2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9857
left/right pattern formation	GO Biological Process Annotations 2025	1.0	null
NCI-H441	COSMIC Cell Line Gene Mutation Profiles	1.0	null
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.78026
Kartagener syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.12
superficial stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42444
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
dextrocardia	MGI Mouse Phenotype Associations 2023	1.0	null
PLPPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25711
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.85998
RAB1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60581
H3K4me1_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MMP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41682
sinusitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.703536
GSE178255_5_v_0_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
INAVA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67992
MOCS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43707
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.776
Lung squamous cell carcinoma_LUSC_TCGA-63-5128-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Outer dynein arm docking complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.44
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JL-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8724844-bt-30-1-98-supple2.xlsx-GO_BP-TFAP4_TFAP4	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5769-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.5806
Alstrom syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.088
Bile duct disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.773
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.31846
Gut microbiota alpha diversity (Shannon index)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.6
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041726
NCI-H446	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Tetralogy of Fallot	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.145
Superior vena cava	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.055
transmembrane transporter complex	GO Cellular Component Annotations 2015	1.0	null
PLEKHA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12145
cerebellar white matter	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11384
GTEX-X4LF-0526-SM-3NMB6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867361
ARHGEF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71628
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.999296
ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
PMC10679662-mmc3.xlsx-NC-D3-ZEB2-Mutant-Upregulated-Gene_Symbol_ZEB2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51969
SSH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38294
ITPRIPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07869
FOXA2-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
Paranasal sinus disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.283
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.13495
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.121503
PTPN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49348
GTEX-WFG8-0001-SM-4LVN8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52824
IP6K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61641
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36683
HT55	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE89154_1_v_0_proscillaridin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-N7MS-0826-SM-2HML4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27132
GTEX-T5JW-1326-SM-4DM5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.925861
AKTIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22066
MYL12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64777
Ion channel complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
HCC2157	CCLE Cell Line Gene Expression Profiles	1.0	1.3711
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
bonemarrow	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.29897
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55584
lethality during fetal growth through weaning	MPO Gene-Phenotype Associations	1.0	null
GSE77108_4_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE235066_4_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
calcium ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.28569
Dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3833
Kidney failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
CALU-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.986414
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QX-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE157592_1_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QH-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
monoatomic cation channel activity	GO Molecular Function Annotations 2025	1.0	null
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.936661
GTEX-QVUS-0011-R4A-SM-3GAE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.905141
METTL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64549
GTEX-RVPU-0011-R7A-SM-2XCAB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837525
SMO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45173
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8637-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59252
Ventromedial hypothalamic nucleus, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33615
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-A4SR-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11083
BTN2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36976
SNRNP40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69059
SW1088	CCLE Cell Line Gene CNV Profiles	1.0	1.40257
NALM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68683
mantle zone of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.90866
Simple lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1749
Congenital chylothorax	ClinVar Gene-Phenotype Associations 2025	1.0	null
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC10123531-NIHMS1874945-supplement-Table_S7.xlsx-SOX17_BCAT_4TCFKO_peaks-Gene_Name_SOX17	Rummagene Transcription Factor Associations 2026	1.0	null
KANSL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46733
NCIH1568	CCLE Cell Line Gene CNV Profiles	1.0	2.31526
Transmembrane transporter complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
K-562	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-POYW-1226-SM-2XCEP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54654
GSE155031_6_v_3_dextran_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POM121	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20954
SF539	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07093
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.77667
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A5A6-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ABC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.41578
mantle zone of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55141
ACKR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19462
LRRC20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09783
Sox3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.3565
GTEX-QV44-0526-SM-2S1RE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903008
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF_D1_vs_D10-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Eye degenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.123
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.974138
GSE233679_6_v_11_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
single-organism developmental process	GO Biological Process Annotations 2015	1.0	null
GEO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
CHD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.495
HEG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98487
GPR37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36196
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.650508
FBXW8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76478
MRPL36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31472
GSE248668_1_v_0_atxn1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Leprosy	dbGAP Gene-Trait Associations	1.0	0.844853
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
EIF4E2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99512
protein complex	GO Cellular Component Annotations 2015	1.0	null
BTBD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42661
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23639
NCI-H520	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hippocampus (hippocampal formation)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.888715
PMC7849364-supp_gad.342378.120_Supplemental_Table_S4_.xlsx-Hoja1-Table_S4-_SIX2-associated_genes_identified_by_CUT_RUN_overlapping_with_differential_expression_by_SIX2_knockdown_SIX2	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal motor neuron morphology	GWASdb SNP-Phenotype Associations	1.0	0.832497
HCC2218	CCLE Cell Line Gene Expression Profiles	1.0	1.93378
MRPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40652
lethality throughout fetal growth and development	MPO Gene-Phenotype Associations	1.0	null
GSE221742,GSE221743_1_v_0_sipa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S3XE-0526-SM-4AD4G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.971361
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044475
GTEX-X8HC-1626-SM-46MWE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58256
GSE112174_5_v_7_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
embryoday7.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.11435
Rectum adenocarcinoma_READ_TCGA-EI-6514-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-PR-A5PG-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FANCM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4225
determination of left/right symmetry	GO Biological Process Annotations 2025	1.0	null
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.973703
HCC1500	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.804212
lethality throughout fetal growth and development, complete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
right pulmonary isomerism	MPO Gene-Phenotype Associations	1.0	null
rhombomere 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32248
CA9-22	COSMIC Cell Line Gene CNV Profiles	1.0	2.08334
GSE130396_1_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE169334,GSE169336_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNHIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53634
salivarygland_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.01388
abnormal embryogenesis/ development	MPO Gene-Phenotype Associations	1.0	null
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
shell of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1253
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0128
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872633
TE9	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36914
MEIOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52313
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.084718
GTEX-R55G-0526-SM-2TC5O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15966
Posterior complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08128
COLO 800	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.937852
dorsal spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04584
CTCF	ENCODE Transcription Factor Targets	1.0	null
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9765
TNFRSF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14386
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1505
abnormal developmental patterning	MPO Gene-Phenotype Associations	1.0	null
Foxo3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.3292
intrinsic component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.12588
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054726
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.76935
PLEK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37031
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57595
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.18456
EOGT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44711
NHLRC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74806
GTEX-V955-1126-SM-4JBH3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24573
ion channel activity	GO Molecular Function Annotations 2015	1.0	null
r6 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57874
NCI-H522	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IGR-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
r4 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.5699
MYC	ENCODE Transcription Factor Targets	1.0	null
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
PAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28707
detection of nodal flow	GO Biological Process Annotations 2025	1.0	null
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.842337
mammillary area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14842
postnatal lethality, incomplete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.6637
EPHB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30507
gallbladder	HPA Tissue Protein Expression Profiles	1.0	1.03161
FUT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42898
retromammillary area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16707
zygote	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.086529
PWWP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38156
TAGLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4473
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.91173
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19082
TLCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51695
CHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31588
MAX	ENCODE Transcription Factor Targets	1.0	null
GSE226285_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883909
GSE210662_2_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44709
Indeterminate Atrial Arrangement	DisGeNET Gene-Disease Associations	1.0	null
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.60494
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834188
EHF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6672
primary visual cortex (striate cortex, area V1/17)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.82848
E2A-27217539-CHIP-SEQ-RAMOS-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-RM2N-0326-SM-48FD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903003
abnormal lung morphology	MPO Gene-Phenotype Associations	1.0	null
SRSF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31909
PMC4407272-elife06857s002.xlsx-Hermes_BRG1-MITF_ComDown-List-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
PANC 05.04	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.33129
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.934316
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01714
chr7_47980239_A_AAG_b38	GTEx eQTL 2025	1.0	1.38156
spleen	HPA Tissue Protein Expression Profiles	-1.0	-1.76538
r7 part of the dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22677
GSE234340_9_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF662	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53201
MOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22298
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.04733
dorsolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.993621
chemdependency	GAD High Level Gene-Disease Associations	1.0	0.293278
Perturb_12224_KD_CASZ1_SRP267080	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.25804
GSE140646_0_v_1_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A74H-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR2C2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA2	ENCODE Transcription Factor Targets	1.0	null
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03224
GTEX-XQ3S-0626-SM-4BOOB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32301
PITX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86488
SHSY5Y	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69329
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49079
Hedgehog signaling complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.648
blood	GTEx Tissue Gene Expression Profiles	-1.0	-1.58427
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.00509
DSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17428
Tobacco Use Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
GFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94978
molecular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5156
Ventromedial hypothalamic nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.03898
TXLNG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03222
mantle zone of r2Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14609
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98529
paranasal sinus disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.70233
Biliary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.768
GSE226115,GSE226116_2_v_0_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
RPP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44798
BTBD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08804
Pectoral fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.665
JRKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44931
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
situs inversus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.03704
SMCO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70044
Lung adenocarcinoma_LUAD_TCGA-44-6144-11A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.994414
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37942
liver	GTEx Tissue Gene Expression Profiles	-1.0	-0.829169
GTEX-S4UY-0126-SM-3K2BB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845311
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.833584
hsa-miR-132	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
HNRNPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.88249
GTEX-RN64-1826-SM-48FDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879952
AR	ChEA Transcription Factor Targets	1.0	null
CITED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50309
AM-38	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Joubert syndrome 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.421
Tongue epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.519
pancreas	GTEx Tissue Gene Expression Profiles	-1.0	-0.906169
Cation channel complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25389
PMC9974104-jci-133-159940-s019.xlsx-GT3-INCP-GATA3_co-bound_genes-Gene_Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE213588_9_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
membrane	GO Cellular Component Annotations 2015	1.0	null
substrate-specific channel activity	GO Molecular Function Annotations 2015	1.0	null
NCIH1650	CCLE Cell Line Gene CNV Profiles	1.0	1.37224
amygdaloid complex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.916632
CDK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64139
Prostate adenocarcinoma_PRAD_TCGA-EJ-7782-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3C7-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TWNK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15287
TNFRSF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41798
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8XE-1926-SM-3DB98	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18076
SPATA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99387
primary auditory cortex (core)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.909911
Oviduct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.3
intermediate stratum of PSPa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14099
G140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.876761
GTEX-R53T-0426-SM-48FEM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.985915
Glossopharyngeal nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.517
HSC-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FHIP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78621
ZNF572	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30269
skin_5e	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.895495
GTEX-OXRK-0126-SM-3NB1E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.921078
GTEX-WYBS-0426-SM-3NM9M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.886163
PMC7818749-12931_2021_1617_MOESM1_ESM.xlsx-TBX4-ENSEMBL_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
ACSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5964
CDK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.475
GTEX-X4XY-1026-SM-46MVX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851417
primary motor cortex (area M1, area 4)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.934077
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08344
PMC9601604-NIHMS1841143-supplement-SuppTable-3.xlsx-shared_downregulated-Genes_downregulated_in_the_absence_of_FOXO3_in_GSCs_and_aged_NSCs_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
SLITRK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00757
YAPC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.4559
SK-MEL-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.91198
Hypoplasia	DisGeNET Gene-Disease Associations	1.0	null
abnormal heart morphology	MPO Gene-Phenotype Associations	1.0	null
SLC35A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08087
superficial stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.43351
Ependymocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.269
GTEX-XYKS-0526-SM-4BRW2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86893
Mesothelioma_MESO_TCGA-MQ-A4LM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.963815
Subcortical maternal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.615
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03338
CCK-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary motor cortex (area M1, area 4)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.950818
fat_a.V1	HPA Tissue Sample Gene Expression Profiles	1.0	1.40715
PMC4407272-elife06857s002.xlsx-Hermes_BRG1-MITF_ComDown-List-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-V1D1-0008-SM-4JBIJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07539
G292CLONEA141B1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76274
Parabrachial nucleus, medial division, external medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01028
Ciliary base	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.0
Lung adenocarcinoma_LUAD_TCGA-55-6985-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
abnormality of the genital system	GWASdb SNP-Phenotype Associations	1.0	0.075872
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PSEN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88989
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37043
CTCF_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
9+0 motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.488
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.517
partial postnatal lethality	MPO Gene-Phenotype Associations	1.0	null
hsa-miR-4483	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GTEX-QLQ7-0526-SM-2I5G3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55157
Perturb_14281_KD_XRN1_ERP131052	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.29839
SK-N-AS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16426
GTEX-R55D-1226-SM-48FE9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909517
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.372369
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MQ-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X638-0326-SM-47JY1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07098
detection of stimulus	GO Biological Process Annotations 2015	1.0	null
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.01889
NCIH727	CCLE Cell Line Gene Expression Profiles	1.0	2.49156
GSE125007,GSE125008_1_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE67266_7_v_3_etoposide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A4XK-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WRHU-1026-SM-4E3ID	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25476
NCI-H524	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WL46-0726-SM-3LK5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84318
abnormal digestive system morphology	MPO Gene-Phenotype Associations	1.0	null
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.225144
NFATC1	ENCODE Transcription Factor Targets	1.0	null
Habenular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.623
SC-198 (CCNE1)	NURSA Protein Complexes	1.0	null
CA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89778
Arid5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.5744
Ventromedial hypothalamic nucleus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32349
Tcf21	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.6538
complete lethality throughout fetal growth and development	MPO Gene-Phenotype Associations	1.0	null
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.09619
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57744
HCFC1R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25582
macromolecular complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Paroxysmal Atrial Fibrillation	DisGeNET Gene-Disease Associations	1.0	null
GTEX-RNOR-0926-SM-2TF56	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28004
GTEX-P78B-0226-SM-3NB1Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869728
GSE213588_9_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary auditory cortex (core)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.28579
Crus 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49467
NRF2-31884422-A549-HUMAN-LUNG-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
Pronephric tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.758
Joubert syndrome 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.37
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.933196
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6817
GTEX-WHPG-0826-SM-3NMBF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06975
Scoliosis, Isolated, Susceptibility To, 3	DisGeNET Gene-Disease Associations	1.0	null
OPM2	CCLE Cell Line Gene Expression Profiles	1.0	1.78722
metabolic	GAD High Level Gene-Disease Associations	1.0	0.293278
hsa-miR-1	MiRTarBase microRNA Targets	1.0	null
Plasma membrane-derived chromatophore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.531
Situs inversus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.769
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.075957
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.13858
Tail bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.104
PMC9996951-40659_2023_417_MOESM3_ESM.xlsx-Osteo_vs_MSC_Array2_hypo_er_txt-Upstream_NAME_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XQ3S-1226-SM-4BOPP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09057
hsa-miR-1324	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GSE169205_3_v_1_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100606_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.7401
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8873
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17702
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.308251
BCL3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TTC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40629
PMC10425715-Supplementary_material-Suppl.2-s2.docx-117-PITX2_PITX2	Rummagene Transcription Factor Associations 2026	1.0	null
HNF4A-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
TC-71	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.901124
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36261
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HT-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bronchus	HPA Tissue Protein Expression Profiles	1.0	1.03161
GSE137177_2_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
intermediate stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01909
GTEX-X88G-0126-SM-47JZ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47156
Bardet Biedl syndrome	WikiPathways Pathways 2024	1.0	null
mesoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.078095
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-S7SE-0726-SM-2XCD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.96061
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PBDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7422
GSE130396_8_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12318984-Table1.xlsx-S7-Table_S7_Instrumental_variables_IVs_identified_from_eQTL_dataset_for_druggable_GIKs_used_in_Mendelian_randomization_MR_analysis_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RN64-1226-SM-2TC6E	GTEx Tissue Sample Gene Expression Profiles	1.0	2.24706
abnormal neuron morphology	GWASdb SNP-Phenotype Associations	1.0	0.832497
NPHP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.702
GSE122378_0_v_1_carmil3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
tobacco use disorder	GAD Gene-Disease Associations	1.0	null
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20013
Joubert syndrome 13	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.056
response to external stimulus	GO Biological Process Annotations 2015	1.0	null
GSE158834_10_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WK11-0526-SM-3NB3O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909786
subethmoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36214
mammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14904
GTEX-U3ZH-1526-SM-4DXV1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5288
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71277
PMC4595011-pgen.1005555.s001.xlsx-MITF_DOWN-regulated-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of the endocrine system	GWASdb SNP-Phenotype Associations	1.0	0.067174
Lung adenocarcinoma_LUAD_TCGA-MN-A4N1-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE101239_3_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XXEK-0926-SM-4BRWH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879361
Male infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.063
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.909911
GTEX-U412-0826-SM-3DB9K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967035
GSE67266_7_v_4_etoposide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
DNASE1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70781
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23828
TGDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8914
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.69578
REH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-T6MN-0926-SM-32PLX	GTEx Tissue Sample Gene Expression Profiles	1.0	3.14659
GTEX-OIZG-0005-SM-2HMJC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15751
HROB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58456
Ellis-Van Creveld syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.38
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.82959
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28372
GTEX-SNOS-0003-SM-3NMAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17437
Congenital diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
Perturb_18442_KD_YAP1/WWTR1_SRP303519	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.0328
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.0696
r5 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55141
cation channel complex	GO Cellular Component Annotations 2015	1.0	null
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
vasculature	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.249653
basal part of terminal hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12868
GTEX-VUSG-0003-SM-3NMDK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51221
infection	GAD High Level Gene-Disease Associations	1.0	0.293278
HUVEC	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	2.71026
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7GZ-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20749
BCL3	ENCODE Transcription Factor Targets	1.0	null
neurodegenerative disease	GWASdb SNP-Disease Associations	1.0	0.318482
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36942
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
GTEX-OIZH-2126-SM-3NB1P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48004
GSE146687_2_v_5_eribulin_human	RummaGEO Drug Perturbation Signatures	1.0	null
JHUEM1	DepMap CRISPR Gene Dependency	1.0	2.22537
Main olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14052
abnormality of monovalent inorganic cation homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.402211
GTEX-WFG8-1926-SM-4LVM1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00321
GTEX-R53T-1626-SM-3GAEW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76611
CLPX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27313
EDEM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54028
GTEX-XMK1-0926-SM-4B66X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99436
Perturb_4369_KD_SUZ12_SRP071040	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.88548
GSE201657_0_v_1_ash2l_human	RummaGEO Gene Perturbation Signatures	1.0	null
TE-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RPSA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64548
abnormal direction of embryo turning	MPO Gene-Phenotype Associations	1.0	null
CL-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.1193
hsa-miR-451b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Mesendoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.714
GTEX-QVUS-0011-R9A-SM-3GIJA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.41322
Paraflocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14791
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66174
cation channel complex	GO Cellular Component Annotations 2025	1.0	null
XRCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40648
GNG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20211
Situs Ambiguous	DisGeNET Gene-Disease Associations	1.0	null
BCP1	CCLE Cell Line Gene CNV Profiles	1.0	1.59275
Perturb_14373_KD_IGF2BP1_SRP150935	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.0949
Mobilized_CD34_Primary_Cells_Female	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.1139
Ventricular septal defect	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.637
cerebellar cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1632
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
C11orf54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53885
heterotaxia	MPO Gene-Phenotype Associations	1.0	null
PCYT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41208
HCC1395	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF605	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13249
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.41322
GSE227698_2_v_1_g0s2_human	RummaGEO Gene Perturbation Signatures	1.0	null
9+0 non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.973
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25967
GTEX-UPIC-0926-SM-4IHLV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.823937
ethmoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34992
GSE186647,GSE217287_1_v_3_hnrnpc_human	RummaGEO Gene Perturbation Signatures	1.0	null
SW620	COSMIC Cell Line Gene Mutation Profiles	1.0	null
G118	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.19395
Cell projection membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.083
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_1day-MOI-10^3_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.97131
TOLEDO	CCLE Cell Line Gene Expression Profiles	1.0	1.5195
MAF1_02_81	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.24793
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.897086
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.831392
GTEX-SNMC-0126-SM-2XCFO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03856
MRPL21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09951
interstitial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.382884
ATM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15582
Polycystic Ovary Syndrome_Skeletal muscle_GSE6798	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.82206
OCIM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40152
spanning component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.218212
POLR1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97724
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.886644
MD-86-UW46_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.237421
SF3B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41556
Anterior olfactory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02369
GSE230263,GSE230265_5_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
DHFR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.099
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13443
GTEX-XQ3S-0526-SM-4BOQA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55253
AP1G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85879
DETROIT562	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XK95-1026-SM-4GIDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903247
Collecting duct cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.57
VDR-23401126-LCL-AND-THP1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC5414054-ncomms15013-s11.xlsx-SupplementaryData10-Supplementary_Data_10_Genes_differentially_expressed_due_to_infection_in_IRF5-_-_compared_to_parent_KOLF2_cells_IRF5	Rummagene Transcription Factor Associations 2026	1.0	null
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.99917
hsa-miR-4793-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
calcium channel activity	GO Molecular Function Annotations 2025	1.0	null
GTEX-T5JC-0526-SM-32PM7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15589
glucose metabolism disease	GWASdb SNP-Disease Associations	1.0	0.230182
Lung squamous cell carcinoma_LUSC_TCGA-60-2706-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDYL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05073
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.908059
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.41322
NR2F1	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-WHPG-0004-SM-3NMDO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91906
CTSV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35538
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41534
detection of nodal flow	GO Biological Process Annotations 2023	1.0	null
PYGL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48182
FU97	CCLE Cell Line Gene Expression Profiles	1.0	1.98062
MTA3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRAF4 (TRAF4)	NURSA Protein Complexes	1.0	null
LN-229	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44578
GSE76771_1_v_3_atf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
determination of left/right symmetry	GO Biological Process Annotations 2023	1.0	null
SW 480	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.848222
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.26
D283MED	CCLE Cell Line Gene CNV Profiles	-1.0	-2.01154
GSE191110_0_v_1_dnajc12_human	RummaGEO Gene Perturbation Signatures	1.0	null
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.6301
PINLYP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33742
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33109
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.16668
Ciliary pocket	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.252
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13684
MORC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34197
SGTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26338
GSE233679_5_v_8_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16906
BL8312 (PAWR)	NURSA Protein Complexes	1.0	null
NCIH1975	DepMap CRISPR Gene Dependency	1.0	4.52464
divalent inorganic cation transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	6.15339
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.2271
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5358-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	1.0	1.35874
Johnston's organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.627
primary visual cortex (striate cortex, area V1/17)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.934077
PANX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52951
OVMANA	CCLE Cell Line Gene CNV Profiles	1.0	2.0193
edema	MGI Mouse Phenotype Associations 2023	1.0	null
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3857
alar part of terminal hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5592
GSE203308_1_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
9+2 non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.733
Cell body membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.004
BCAP31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29652
Intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
H3K4me1_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-1265	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
496100605_TCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.51144
HSPA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71296
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table3_WBBC_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-7669-01A-21R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.18481
macromolecular complex	GO Cellular Component Annotations 2015	1.0	null
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43097
PLD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91575
Plasma membrane region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.794
Kidney - Cortex	GTEx Tissue Gene Expression Profiles 2023	1.0	3.29115
SUDS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04426
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01982
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RX-A8JQ-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
retromammillary area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02004
JHH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.895204
Perturb_8929_KD_CHD4/ARID1A_SRP350011	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.86152
type ii diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.433364
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-X585-0008-SM-46MU4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.996813
DLAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73944
GCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74555
r4 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8337
SCARA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81011
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
morula	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.092944
type 2 diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.507105
Waist-to-hip ratio adjusted for BMI (additive genetic model)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.539794
H3K23ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-519e	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
TMEM200C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25735
TGBC11TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NKM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE126127_2_v_1_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4595011-pgen.1005555.s003.xlsx-BPTF_DOWN-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
Heart septal defect	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.605
P30-OHK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.95827
GTEX-X88G-0004-SM-47JZ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10711
SKN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SK-UT-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mediodorsal nucleus of thalamus_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.904553
PMC8755726-42003_2021_2958_MOESM6_ESM.xlsx-489_corr_genes_TWIST1_signature-Gene_name_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
LUDLU1	DepMap CRISPR Gene Dependency	1.0	2.48492
NUGC4	CCLE Cell Line Gene CNV Profiles	1.0	1.54227
NUGC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_18443_KD_YAP1/WWTR1/CGAS_SRP303519	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.46537
SLR24	CCLE Cell Line Gene Expression Profiles	-1.0	-1.70159
GTEX-OIZG-1126-SM-2HMIU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43688
GSE138872,GSE138874_0_v_1_il33_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RNF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85387
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5693-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE209938_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QXCU-0006-SM-2TC5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34206
Axonemal central apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.073
MARK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16713
Lung squamous cell carcinoma_LUSC_TCGA-43-3394-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.047848
situs inversus	MGI Mouse Phenotype Associations 2023	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3TX-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WH7G-0426-SM-3NMBJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06055
Obstructive sleep apnea during REM sleep (apnea hypopnea index)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.609691
r7 part of cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16455
abnormal lung position or orientation	MPO Gene-Phenotype Associations	1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.82708
MAFF	ENCODE Transcription Factor Targets	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
Anterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.02885
dorsal lateral geniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33072
Supplemental somatosensory area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58317
NB12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE145323,GSE145324_9_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary auditory cortex (core)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04484
calcium channel complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
CBS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45109
SNU-449	COSMIC Cell Line Gene Mutation Profiles	1.0	null
nasopharynx	HPA Tissue Protein Expression Profiles	1.0	1.03161
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.984692
Cholangiocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.797
GCT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SIU8-0826-SM-2XCDQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33139
INIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43815
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-U8XE-0005-SM-3DB8I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37093
NKX6-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02165
Anterior cingulate area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11929
Nucleus reuniens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.529
AASDHPPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5397
DACH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25924
HCC1806	CCLE Cell Line Gene Expression Profiles	1.0	1.88059
centriole	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.421604
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.41322
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.51005
U178	CCLE Cell Line Gene Expression Profiles	-1.0	-1.89942
Gastric	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.40415
non-motile cilium	GO Cellular Component Annotations 2023	1.0	null
JK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6521
dorsomedial part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33052
NCI-H748	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.940597
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.888142
HCC-827	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.836562
GSE130475_1_v_2_thpo_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cation transport	GO Biological Process Annotations 2015	1.0	null
ATMIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39381
Neural tube	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.455
PMC5291205-srep41905-s3.xlsx-LPS_datasets_gmx-Unnamed_2_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-UPIC-0726-SM-3GADW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98707
SNU13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8138
membrane part	GO Cellular Component Annotations 2015	1.0	null
SAYSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.80623
GSE135352_0_v_4_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.22992
HSC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
calcium channel complex	GO Cellular Component Annotations 2015	1.0	null
GTEX-S4Q7-0003-SM-3NM8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48977
motor neuron disease	GWASdb SNP-Disease Associations	1.0	0.945129
GPR107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1578
SNU410	CCLE Cell Line Gene CNV Profiles	1.0	2.31088
Heterotaxy, Visceral	DisGeNET Gene-Disease Associations	1.0	null
PMC11058205-42003_2024_6202_MOESM5_ESM.xlsx-Data2c_CEBPA_ChIP-Unnamed_9_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1569	COSMIC Cell Line Gene Mutation Profiles	1.0	null
r3 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.94118
OSC-19	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S33H-0326-SM-4AD6N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18124
ZCCHC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81795
GTEX-VJYA-0826-SM-4KL1M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895687
CD4_Naive_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.05807
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.300679
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.7015
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_7day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.58786
GTEX-TML8-1226-SM-32QON	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940416
SOX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50266
sin3a_22783022_mcf7_lof_human_gpl570_gds4388	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.284599
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.19957
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r2 part of principal trigeminal sensory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19447
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.17914
Hoxa11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.4674
hsa-miR-622	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
COLO680N	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6629
GTEX-UPK5-1826-SM-3GAEB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.928144
Fetal_Intestine_Large	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.828106
PRR13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66205
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Infralimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.76127
GSE252958_1_v_0_znf469_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00224
Hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.208
MAFK	ENCODE Transcription Factor Targets	1.0	null
PKIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26902
LOVO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Adult liver stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.782
GADD45A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82242
PRDX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43229
PHYHIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67354
left/right axis specification	GO Biological Process Annotations 2023	1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.909911
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RN64-0626-SM-2TC5V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62343
DCUN1D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78871
DACT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15857
Perturb_13952_OE_lncNR2F1_SRP179994	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.34083
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03802
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-OIZF-1526-SM-3MJGY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24141
intrinsic component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.098698
SK-MEL-24	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Declive (VI)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05814
PPARD	ChEA Transcription Factor Targets	1.0	null
PMC9950457-mmc3.xlsx-AP2A_binding_sites_GRHL2_KO-LRRC32_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-VJYA-1426-SM-4KL1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89543
GSE245270_1_v_5_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WFON-0001-SM-3P61W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.987987
urinary bladder	HPA Tissue Protein Expression Profiles	1.0	1.03161
GTEX-X4XX-0011-R6B-SM-46MWP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88051
MESSA	CCLE Cell Line Gene CNV Profiles	-1.0	-1.82442
Kidney Chromophobe_KICH_TCGA-KL-8344-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ABHD14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49069
GSE63048_11_v_6_morc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hydrocephalus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.634349
nonmotile primary cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.98927
Prostate adenocarcinoma_PRAD_TCGA-V1-A8WW-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PW2O-0008-SM-48TEB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02626
r2 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.90866
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.41322
PKD domain	InterPro Predicted Protein Domain Annotations	1.0	null
divalent inorganic cation transport	GO Biological Process Annotations 2015	1.0	null
GTEX-WEY5-0001-SM-3P61Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10424
MYLA	DepMap CRISPR Gene Dependency	1.0	4.16502
GOLIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5978
Cholestasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.011
HNRNPL_02_96	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.85798
transporter activity	GO Molecular Function Annotations 2015	1.0	null
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.830418
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CAL54	CCLE Cell Line Gene CNV Profiles	1.0	1.39661
IM-95	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RWSA-0626-SM-2XCBD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882322
FAM118A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11852
CBX2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STS-0421	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.756
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02528
Atrial appendage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.879
anterior (rostral) cingulate (medial prefrontal) cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.35829
U2OS	CCLE Cell Line Gene Expression Profiles	1.0	1.41675
GTEX-XYKS-1526-SM-4BRUP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25321
RNASE8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57026
Parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.41912
NCI-SNU-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2374
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.81853
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A94W-01A-12R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
u266	HPA Cell Line Gene Expression Profiles	1.0	1.85949
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7382-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFJO-0002-SM-3P61X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15756
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9756
hela	HPA Cell Line Gene Expression Profiles	-1.0	-1.15888
Perturb_2390_KD_HIF1A/HIF2A_SRP308699	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.2853
protein binding	GO Molecular Function Annotations 2015	1.0	null
CDC26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10878
GTEX-X5EB-2626-SM-4E3HZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.952271
MFE319	CCLE Cell Line Gene Expression Profiles	1.0	1.49339
intermediate stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29167
cerebellar cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.01086
GTEX-UPK5-0003-SM-3NMDI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.916303
respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.068022
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0936
GTEX-P4QS-0326-SM-2I3EU	GTEx Tissue Sample Gene Expression Profiles	1.0	2.95335
Granular lamina of the cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.97312
internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.268137
RBFOX2_02_139	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.24793
primary cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.813487
r10 part of external cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0969
ion transport	GO Biological Process Annotations 2015	1.0	null
CHST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46199
Nodal receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.918
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal embryo turning	MPO Gene-Phenotype Associations	1.0	null
FARSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34618
lateral part of MM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21086
CALU-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21681
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54504
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70335
SW1783	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MYC_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.83835
SNAI1_OE_GDS4596_344_human_SW480 - Colorectal cancer cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE101239_5_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14672
reproductive system disease	GWASdb SNP-Disease Associations	1.0	0.125339
Unbalanced Atrioventricular Canal Defect	DisGeNET Gene-Phenotype Associations	1.0	null
Notochord	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.624
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUS-01A-12R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
OBI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80368
SMURF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5091
3asube	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.974
RECQL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41219
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MESSA	CCLE Cell Line Gene Expression Profiles	1.0	1.62039
888	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.5382
hsa-miR-3128	TargetScan Predicted Conserved microRNA Targets	1.0	0.568687
GTEX-U3ZN-0226-SM-3DB8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848343
primary auditory cortex (core)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.964944
GSE178255_3_v_0_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal internal genitalia	GWASdb SNP-Phenotype Associations	1.0	0.124338
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21535
HS 683	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.846713
Paramedian lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41289
monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.699919
cerebral degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.343106
LRFN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.24042
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01995
PMC9643473-Table1.xls-MAF_0_005-Gene_refGenecanonical_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
ion channel complex	GO Cellular Component Annotations 2015	1.0	null
hsa-miR-632	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GTEX-QDT8-0426-SM-32PKZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.96775
KP-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SDF2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28699
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0011
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4991-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Crus 2, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53324
intermediate stratum of PPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12439
KMS-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table8_gnomAD_AFR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
SMOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52065
GSE179031_3_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Axonemal central pair	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.088
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20958
r9 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48939
Inner dynein arm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.188
Situs Inversus	DisGeNET Gene-Disease Associations	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05828
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A6-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06086
Prostate adenocarcinoma_PRAD_TCGA-KC-A7F5-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-LHX6_LHX6	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23335
Anterior hypothalamic nucleus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.865
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042746
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A3PH-01A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r4 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.3708
JUND-26020271-SMOOTH-MUSCLE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Annular pancreas	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.307
NCI-H1299	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.42115
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.7828
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.960399
GTEX-VUSG-2426-SM-4KKZG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874047
ATP5PB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82158
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.884558
PMC11522069-439_2024_2703_MOESM2_ESM.xlsx-Table_S3-HsCHD_AR_N_115_AR	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13923
hippocampus (hippocampal formation)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09857
SMG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12404
brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.062314
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
COLO-679	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-REY6-0726-SM-2TF4M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17598
GSE159678_4_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ARHGEF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22181
PNMA6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48356
PRSS50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3372
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC5095001-oncotarget-07-36293-s002.xlsx-Table_S2-Table_S2_MYCN-correlated_genes_and_their_correlations_with_other_transcription_factors_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19H-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9558712-Data_Sheet_2.xlsx-POU3F4_WT_vs_CTRL-gene_name_POU3F4	Rummagene Transcription Factor Associations 2026	1.0	null
SNU-61	COSMIC Cell Line Gene CNV Profiles	1.0	2.08334
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Ventral part of the lateral geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32066
Left atrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.987
premature ovarian failure	GWASdb SNP-Disease Associations	1.0	0.500035
abnormality of the ovary	GWASdb SNP-Phenotype Associations	1.0	0.248643
GTEX-X5EB-0004-SM-46MWA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01966
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.073965
GTEX-OIZG-1026-SM-3LK5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874494
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72883
LU-99A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XGQ4-0008-SM-4AT3Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03472
GTEX-TMMY-0126-SM-4DXTP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09107
HCC202	DepMap CRISPR Gene Dependency	1.0	2.5407
XPNPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81745
protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65452
SNU1079	CCLE Cell Line Gene CNV Profiles	1.0	1.49917
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.94176
SHISA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19031
UBE2O	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7961
TELO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8273
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE188458_2_v_1_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	1.0	null
amygdaloid complex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.03899
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838903
VM-CUB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Polydactyly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.661
CEBPB	ENCODE Transcription Factor Targets	1.0	null
GSE145323,GSE145324_3_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07256
Intraciliary transport particle B	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.421
COLO-684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTAGE6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9923
GTEX-PWN1-1526-SM-48TDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.854303
SK-N-SH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC12183081-41388_2025_3375_MOESM8_ESM.xlsx-Sheet1-Table_S7_List_of_differentially_alternative_splicing_genes_in_osteosarcoma_cell_lines_after_knocking_down_the_YBX1_gene_P_0_05_Related_to_Fig_6C_YBX1	Rummagene Transcription Factor Associations 2026	1.0	null
NLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83655
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.10045
HBA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60802
GSE233679_14_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
STAT5A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA2-19822575-HEPG2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
retina	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.837231
GSE102132_2_v_1_irf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22541
Bone development disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.062
GSE233679_6_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
periventricular stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.936
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32276
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46636
abnormal embryonic growth/weight/body size	MPO Gene-Phenotype Associations	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23552
MOR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20958
RBM15_02_171	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.90689
GSE136622_0_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OAW-28	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-7771-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHF8-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CEP192	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13306
GTEX-U8XE-0426-SM-3DB91	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1059
MKKS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13818
GTEX-WFON-1726-SM-4LVMQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841339
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44972
Gastrula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.331
PMC8567280-EMBR-22-e53014-s007.xlsx-Sheet1-Nearest_genes_to_BAZ2A-bound_C2-Enhancers_BAZ2A	Rummagene Transcription Factor Associations 2026	1.0	null
FOXA2	ChEA Transcription Factor Targets	1.0	null
mIMCD-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.26
SALL4	ChEA Transcription Factor Targets	1.0	null
GTF2F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22265
GTEX-XQ3S-1026-SM-4BOPJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11399
CEMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70205
GTEX-Q2AI-0226-SM-48U1D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06081
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.990351
Hydrocephalus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.504
posterior part of anterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15184
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13876
PMC12178937-mmc6.xlsx-L_MT1_KDvsD_MT1_KD_deg_all-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
496100645_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.13811
mammary gland tumor cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.443347
GTEX-S32W-0926-SM-4AD5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.908378
GTEX-XPVG-2226-SM-4B65U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22366
ZNF395_02_69	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.52356
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.57901
GTEX-O5YT-2126-SM-3MJGD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32783
testis_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.07289
GATA2_02_28	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.64386
BL7235 (MAP3K1)	NURSA Protein Complexes	1.0	null
TDRD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80837
TOX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70828
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-XPT6-0001-SM-4B64G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43501
Kidney Chromophobe_KICH_TCGA-KO-8410-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10933434-44319_2024_69_MOESM2_ESM.xls-HRV16-UV_vs_MI-Ensembl_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
PSMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77599
HT-144	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.87112
ZNHIT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76061
NB17	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.95555
GSE139540_3_v_2_menadione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8333-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Axonemal dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.7
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.879718
GSE135352_2_v_3_napabucasin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cerebellum	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.862044
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.929976
OV56	CCLE Cell Line Gene Expression Profiles	1.0	1.50302
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.174
SLCO4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9602
GTEX-U4B1-0326-SM-3DB8K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867899
GSE80098,GSE80366_0_v_6_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.41322
SPHK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99853
PLEKHM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24688
FOXM1	ENCODE Transcription Factor Targets	1.0	null
GTEX-WZTO-1326-SM-3NM8X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56191
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.813
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.1073
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09285
NTAQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54537
Lung squamous cell carcinoma_LUSC_TCGA-77-A5GH-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WM793	CCLE Cell Line Gene CNV Profiles	1.0	1.3674
SRD5A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11207
PMC8851354-Table_6.xlsx-STAT3-bound_genes_GM12878-Supplementary_Table_6_STAT3-bound_unique_genes_in_GM12878_cells_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE233679_6_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15657
nonmotile primary cilium	GO Cellular Component Annotations 2015	1.0	null
GSE237053_1_v_0_comt_human	RummaGEO Gene Perturbation Signatures	1.0	null
Brain - Substantia nigra	GTEx Tissue Gene Expression Profiles 2023	1.0	1.08088
SELENOM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54223
AR-20517297-VCAP-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SUP-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55D-0008-SM-48FEV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856615
Serous carcinoma_Fallopian tube_GSE10971	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.73044
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38161
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.049184
COX7C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16364
CALHM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44369
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6591
GTEX-WYJK-0005-SM-3NMA1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20132
18801183-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
ECC10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Ventromedial hypothalamic nucleus, dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41509
GSE152699,GSE152723_3_v_2_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.657
PMC4595011-pgen.1005555.s001.xlsx-BPTF_DOWN-regulated-Gene_name_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
Infundibulocystic basal cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.076
CHRD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08163
CAMSAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07204
GSE71529,GSE71558_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
UBE2F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62849
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.23604
GSE176008_4_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8684775-CTM2-11-e640-s002.xlsx-Sheet1-Table_S3_MAF_file_of_the_CCS_samples_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01882
EFM192A	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32666
Gall bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.176
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44Q-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.001
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.8132
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98972
TUT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88734
BRINP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34928
abnormality of cardiac morphology	GWASdb SNP-Phenotype Associations	1.0	0.85593
Perturb_8028_KO_IRTKS_SRP310479	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
motor neuron atrophy	GWASdb SNP-Phenotype Associations	1.0	0.832497
SR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.882899
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4999-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.34131
Biliary tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.77
NUGC-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cation transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
ARFGEF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.74127
PKD/Chitinase domain	InterPro Predicted Protein Domain Annotations	1.0	null
GSE164087_0_v_1_jmjd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PXYLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85913
abnormal heart position or orientation	MPO Gene-Phenotype Associations	1.0	null
gonad	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.432225
CatSper complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.445
GSE216273,GSE216292_0_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MED12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1988
NDUFA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81253
CABLES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64863
NCI-H23	COSMIC Cell Line Gene Mutation Profiles	1.0	null
JMSU1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39371
calcium channel complex	GO Cellular Component Annotations 2025	1.0	null
PCYOX1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45296
AGPAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50836
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3Y7-01A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
right pulmonary isomerism	MGI Mouse Phenotype Associations 2023	1.0	null
female reproductive system disease	GWASdb SNP-Disease Associations	1.0	0.198903
cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.464798
GSE192513,GSE192515_1_v_0_atg16l1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
nose disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.344207
GTEX-UPK5-0326-SM-3GAF3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65134
GTEX-P44H-0726-SM-48TBT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74121
ANGEL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05077
layer 6a of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08274
Lung squamous cell carcinoma_LUSC_TCGA-85-8352-01A-31R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.048521
ALG10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44918
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.43445
PMC6928094-395_2019_765_MOESM7_ESM.xls-DEGs_AR7_vs_Pre-patterned-List_of_differentially_expressed_genes_in_AR7_vs_Pre-patterned_cells_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
respiratory system phenotype	MPO Gene-Phenotype Associations	1.0	null
Bile canaliculus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.907
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0116
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.57288
Visceral heterotaxy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.807
FOXM1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TM31	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51607
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28281
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.14642
H4	CCLE Cell Line Gene CNV Profiles	1.0	1.67844
Arthrogryposis multiplex congenita-6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.525
Perturb_8924_KD_LINC01133a_SRP320645	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.1455
Perturb_18444_KD_YAP1/WWTR1/STING1_SRP303519	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.40724
Acute Myeloid Leukemia_LAML_TCGA-AB-2838-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10357
abnormal fluid regulation	MPO Gene-Phenotype Associations	1.0	null
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-S4Z8-0008-SM-33HAZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17997
NB(TU)1-10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042173
TFR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64463
GSE157777_2_v_3_foxa3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.828612
TOV-21G	COSMIC Cell Line Gene Mutation Profiles	1.0	null
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17953
SUP-M2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Stereocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.841
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81P-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10245467-mmc3.pdf-266-TBX2_TBX2	Rummagene Transcription Factor Associations 2026	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2992-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8437976-41416_2021_1470_MOESM2_ESM.xls-List_of_MAF_in_SNP_Rectum-Hugo_Symbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF266	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06128
Polycystic kidney disease 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.315
bed nucleus of stria terminalis, lateral amygdaloid division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05996
KYAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.95754
HCC2157	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NIBAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03398
RPMI-8226	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SLC45A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50285
Perturb_14601_KO_ASAP2_SRP258574	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
VMRCRCW	CCLE Cell Line Gene Expression Profiles	1.0	1.37716
E2F1-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-QCQG-0126-SM-48U27	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.949621
GTEX-U3ZH-0326-SM-3DB7A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0353
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75991
LLC-PK1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.163
Perturb_5393_KD_LIM1_SRP402415	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.64312
Medullary collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.018
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053131
ATP8B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32327
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.71374
vascular disease	GWASdb SNP-Disease Associations	1.0	0.096655
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Distal-RefSeq_Name_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE242083,GSE242098_3_v_5_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CEP250	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80918
upper (rostral) rhombic lip_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.882848
JURL-MK1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BANP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19324
S1PR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83103
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
prenatal growth retardation	MPO Gene-Phenotype Associations	1.0	null
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058055
mantle zone of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16798
GSE227698_2_v_4_g0s2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4899-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anterior hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.07775
PRDM12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11937
TE-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hypertension	GWASdb SNP-Disease Associations	1.0	0.971735
STRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60049
HCC1599	CCLE Cell Line Gene CNV Profiles	-1.0	-2.3514
U2SURP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.97599
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
RPS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22152
RASA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94826
H3K4me1_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4338-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ILF3_02_148	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.80735
Bile duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.842
AMDHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10944
LENG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4806
mortality/aging	MPO Gene-Phenotype Associations	1.0	null
GTEX-OHPN-0011-R4A-SM-2I5FD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1884
KLHL34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96918
RRBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98689
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.926379
NCIH2073	CCLE Cell Line Gene CNV Profiles	1.0	2.20467
breast	GTEx Tissue Gene Expression Profiles	1.0	0.895787
MIA PACA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.917492
Meckel syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.405
posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20334
hsa-miR-4430	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
homeostasis/metabolism phenotype	MPO Gene-Phenotype Associations	1.0	null
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75821
GTEX-OIZI-0126-SM-3NB13	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921983
RIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54857
Tail fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.811
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64972
heart_6b	HPA Tissue Sample Gene Expression Profiles	1.0	1.01822
gastrula	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.807716
Ciliary transition fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.637
cardiovascular system phenotype	MPO Gene-Phenotype Associations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WL-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
parathyroid gland	HPA Tissue Protein Expression Profiles	1.0	1.03161
OVISE	CCLE Cell Line Gene CNV Profiles	1.0	1.69535
GTEX-W5X1-0001-SM-3P61V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91057
IPO8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9802
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_1day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.77851
GSE242290_1_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19704
GSE58724_1_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-SUCS-0002-SM-3NMAJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935153
hsa-miR-4680-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GSE227698_2_v_0_g0s2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-A4M2-01A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dextrocardia	MPO Gene-Phenotype Associations	1.0	null
Ciliary necklace	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.273
vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053257
VMRC-LCD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.2926
FOXM1_02_37	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.80735
heart	GTEx Tissue Gene Expression Profiles	1.0	1.76929
ZNF730	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52251
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.52318
Sodium	dbGAP Gene-Trait Associations	1.0	0.300307
RS411	CCLE Cell Line Gene CNV Profiles	-1.0	-1.80216
EZH2	ENCODE Transcription Factor Targets	1.0	null
PMC7291745-12967_2020_2407_MOESM2_ESM.xlsx-Table_S1D_CCF_pairs-locus_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
Fetalliver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.88071
striatum_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.18579
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.65231
KYSE-510	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Right atrial isomerism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.5
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.876231
GTEX-U3ZN-1426-SM-3DB87	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32507
PMC9996951-40659_2023_417_MOESM3_ESM.xlsx-Osteo_vs_MSC_Array2_hypo_er_txt-1_UCSC_NAME_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Spiral organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.181
SNU1033	CCLE Cell Line Gene CNV Profiles	-1.0	-2.20312
GTEX-T5JW-1626-SM-3GADZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17453
GTEX-XPVG-1526-SM-4B66C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.931428
GTEX-VUSG-0126-SM-4KL1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25558
DSG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91122
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC4595011-pgen.1005555.s003.xlsx-BPTF_DOWN-regulated-Gene_name_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
PCGF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33348
cation transmembrane transport	GO Biological Process Annotations 2015	1.0	null
PMC10933434-44319_2024_69_MOESM2_ESM.xls-HRV16-UV_vs_MI-Associated_Gene_Name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE222574_0_v_2_lmna_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE230263,GSE230265_0_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
NR3C1-21868756-MCF10A-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H1435	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_10637_KO_Sip1_SRP028877	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GTEX-QDVJ-0008-SM-48U2E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02027
NCI-H1568	COSMIC Cell Line Gene CNV Profiles	1.0	2.08334
PMC10247733-41408_2023_863_MOESM2_ESM.pdf-387-PITX2_PITX2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P78B-0426-SM-2I5F5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04296
Hatching gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.88
HOXB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66365
biological_process	GO Biological Process Annotations 2015	1.0	null
QSER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70845
GSE247764_4_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03969
urinarybladder_5b	HPA Tissue Sample Gene Expression Profiles	1.0	0.840965
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A6W2-06A-22R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
voltage-gated calcium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.074
HEXB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.3704
AM38	DepMap CRISPR Gene Dependency	1.0	2.54698
Renal medulla cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.646
orbital frontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16881
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table7_gnomAD_AMR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S3XE-0126-SM-4AD4R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08872
GTEX-QEG5-0326-SM-2S1PB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854932
LARP4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69795
Perturb_14582_KO_NQO1_SRP217327	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.72982
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08268
embryonic growth retardation	MGI Mouse Phenotype Associations 2023	1.0	null
superficial stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09848
GTEX-XMK1-2026-SM-4B65K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57537
Ciliopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.504
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_induced_genes-Unnamed_6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Arcuate hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24059
BNIP3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42733
STEAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3331
ERCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75709
abnormality of the female genitalia	GWASdb SNP-Phenotype Associations	1.0	0.13412
ATP5MGL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21046
GTEX-W5X1-0006-SM-3GIJZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.41322
DANG	CCLE Cell Line Gene CNV Profiles	1.0	1.73396
NR2C2	ENCODE Transcription Factor Targets	1.0	null
Anterior olfactory nucleus, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03372
Lung squamous cell carcinoma_LUSC_TCGA-56-8307-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Nde	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.7
growth/size/body phenotype	MPO Gene-Phenotype Associations	1.0	null
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_14537_KO_NTNG1_SRP278999	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.63321
SK-MEL-31	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KMS-12-BM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WL46-2026-SM-3LK7U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82987
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_induced_genes-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CCDC28A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17864
INTS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06787
GTEX-S33H-0008-SM-4AD6C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61081
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971416
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SOX2	ChEA Transcription Factor Targets	1.0	null
GTEX-QVJO-1626-SM-2S1QW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848579
AEBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71698
HNF4A	ChEA Transcription Factor Targets	1.0	null
PFDN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86065
PMC9235320-mmc2.xlsx-ST9_eQTL-MR-results-Supplementary_Table_9A_The_effects_of_whole_blood_transcripts_on_COVID-19_severity_with_suggestive_Mendelian_randomization_evidence_P_0_05_using_Genomicc_data_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
dextro-looped transposition of the great arteries	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.329
SPOUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38274
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.14642
GTEX-P4QT-0126-SM-2I3FL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0791
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.31069
GTEX-V955-1926-SM-4KL1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51411
calcium ion transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
GTEX-S7SE-0826-SM-4AT4D	GTEx Tissue Sample Gene Expression Profiles	1.0	2.99955
GSE158431_5_v_1_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17155
detection of mechanical stimulus	GO Biological Process Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4355-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chr7_47949294_G_A_b38	GTEx eQTL 2025	1.0	2.2565
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.33129
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE166315_1_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.5501
GTEX-V1D1-0526-SM-4JBGW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26698
GSE122215,GSE122217_0_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDS - Myelodysplastic syndrome_Bone marrow stem cell_GSE4619	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.49801
SLR26	CCLE Cell Line Gene Expression Profiles	-1.0	-1.86292
cell projection	GO Cellular Component Annotations 2015	1.0	null
TIGD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01297
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.41322
DISP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52616
G6PC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32868
GTEX-QLQW-1226-SM-2S1Q9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67166
THOC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17667
OAW-42	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE121866_0_v_2_six4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Heart primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.51
light-harvesting complex, peripheral complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.627
u2197	HPA Cell Line Gene Expression Profiles	-1.0	-1.15888
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23674
Fetal Kidney	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.10111
ECC12	CCLE Cell Line Gene Expression Profiles	-1.0	-1.93992
Adrenocortical carcinoma_ACC_TCGA-P6-A5OG-01A-22R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AR-20517297-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.98836
TMEM265	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58542
Polycystin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.821
GTEX-P4PQ-0008-SM-48TDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03366
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9058
UPCISCC200	DepMap CRISPR Gene Dependency	1.0	4.07045
GSE80098,GSE80366_0_v_8_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
spanning component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.218212
MDFI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01168
r6 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45385
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.983377
RBM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46224
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.942
PMC10149505-41392_2023_1393_MOESM2_ESM.xlsx-CPCMR-Hugo_Symbol_MEIS2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69014
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-8596-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.0413
preweaning lethality	MPO Gene-Phenotype Associations	1.0	null
GTEX-U3ZN-2626-SM-3DB7T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996442
Congenital kyphosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9014
M14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cAMP-dependent protein kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.785
SNU-407	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA3	ENCODE Transcription Factor Targets	1.0	null
substrate-specific transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-TML8-0526-SM-32QOQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67306
MTRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4975
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.19956
detection of abiotic stimulus	GO Biological Process Annotations 2015	1.0	null
FCGRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91104
8MGBA	CCLE Cell Line Gene Expression Profiles	-1.0	-2.36789
NCI-H526	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.905953
GTEX-S7SE-0226-SM-2XCD4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88304
GSE60217_1_v_2_inosine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MTPAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71141
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3324
Purkinje cell layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59428
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3376-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.2302
SYNCRIP_OE_GDS4596_85_human_SW480	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SOX2-21211035-LN229-GBM	ChEA Transcription Factor Targets 2022	1.0	null
orbital frontal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.909911
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.85026
PAX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68869
GTEX-XOT4-0826-SM-4B66Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829234
hsa-miR-618	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
TMEM59L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57859
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.1193
Archenteron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.053
GSE234334,GSE234336_1_v_0_zhx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XAJ8-0226-SM-4GIB2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861902
abnormal digestive organ placement	MPO Gene-Phenotype Associations	1.0	null
Axoneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.053
GTEX-RWSA-0008-SM-47JYX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40754
Plasma membrane region	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Prostate adenocarcinoma_PRAD_TCGA-HC-7077-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Asphyxiating thoracic dystrophy 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.136
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.14688
Visceral endoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.533
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6689
U266B1	CCLE Cell Line Gene Expression Profiles	1.0	2.34955
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.48979
GSE102132_0_v_1_irf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Chromosome 15q11.2 deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.177
SW620	DepMap CRISPR Gene Dependency	1.0	23.8598
PBX1	ChEA Transcription Factor Targets	1.0	null
SAS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CHN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2991