association	dataset	threshold value	standardized value
FARAGE	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PIP(18:0/18:3(6Z,9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
PIP(16:0/20:2(11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.85091
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MARCKSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14799
ARL4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56362
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.61656
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DAPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07277
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
hsa-miR-26b	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
PI(18:2(9Z,12Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
LMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65476
hsa-let-7a	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
MEL-HO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
layer III of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.898593
hsa-miR-556-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
SMAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4798
periventricular stratum of isLim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33402
A549_AC480_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0118312
ZNF365	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67613
GSE80446_2_v_1_anakinra_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HES4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02938
A549_Decitabine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0169476
Magnocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09136
Bipolar disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.421
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A5SJ-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26588
A549_Ivosidenib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.018558
H3K9ac_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.087147
PI(18:3(6Z,9Z,12Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PIP(18:1(9Z)/20:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
PIP2(18:0/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
PIP2(18:2(9Z,12Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
PARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40971
Perturb_8969_KD_TBX3_SRP068139	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
SERPING1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20142
Lung squamous cell carcinoma_LUSC_TCGA-85-6175-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.909981
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Tanycyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.819
MCF7_SL-327_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0187471
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.915717
GSE131798,GSE131804_2_v_0_igf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormality of cellular immune system	GWASdb SNP-Phenotype Associations	1.0	0.098885
MECOM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28401
LI7	CCLE Cell Line Gene Expression Profiles	1.0	1.46109
GTEX-R55D-0008-SM-48FEV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4735-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38301
Inhibin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.704
III, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.2447
hsa-miR-302e	TargetScan Predicted Conserved microRNA Targets	1.0	0.085563
GTEX-SE5C-0626-SM-2XCDV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45656
MARCHF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91765
GTEX-WFJO-0008-SM-4LVN7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26525
MCF7_Ki16425_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0165555
IV	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03468
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_12_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WEY5-0001-SM-3P61Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877476
GTEX-WFG8-0626-SM-3GILJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34467
Diastolic blood pressure response to hydrochlorothiazide in hypertension	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.51549
SUZ12-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-4530	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
DICER1_KO_GDS4504_584_mouse_bone marrow granulocyte-macrophage progenitors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
m2 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50966
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BHY	CCLE Cell Line Gene CNV Profiles	1.0	1.959
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7SF-0008-SM-3NM8T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30594
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.055
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XV7Q-1426-SM-4BRWA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.12379
layer IIIu of area 35r	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12131
Perturb_14660_KO_Insm1|Neurod1_ERP127840	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-19.5229
hsa-miR-1183	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.056575
STK11IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82033
hsa-miR-4420	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
ZNF131	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.0534
GSE193258,GSE193259_5_v_15_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_R_species_not_found_in_common_genes_of_LF_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QDT8-0011-R11A-SM-32PKD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6405
PIP2(18:0/20:2(11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
GSE134615_1_v_0_lats1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.70882
A549_Trichostatin A_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.014346
MHHNB11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52893
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
PI(18:0/22:5(4Z,7Z,10Z,13Z,16Z))	HMDB Metabolites of Enzymes	1.0	null
MCM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49789
ventrolateral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21691
CA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42802
Ventromedial hypothalamic nucleus, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06545
EBC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
A549_JNJ-7706621_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0212229
layer II of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.825057
PI(18:3(6Z,9Z,12Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
PIP2(16:1(9Z)/16:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE217115_3_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-33b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02125
septopallidal shell area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04375
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PI(18:1(11Z)/18:3(9Z,12Z,15Z))	HMDB Metabolites of Enzymes	1.0	null
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.72265
hsa-miR-548b-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
MCF7_Nintedanib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0124973
PIP2(20:4(5Z,8Z,11Z,14Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
amygdaloid complex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.976557
GH3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.884
GSE242521,GSE242522_0_v_1_mettl3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T2IS-0011-R11A-SM-32QPC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90655
GSE140965_1_v_4_mybpc3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PI(18:0/18:0)	HMDB Metabolites of Enzymes	1.0	null
reticular nucleus of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.933849
pancreas	HPA Tissue Protein Expression Profiles	1.0	1.51891
tgp52	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.478
GATA4_INACTIVATION_GDS3663_519_mouse_Endothelial-derived cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BEN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5884-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of isBL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.52718
Urogenital Abnormalities	CTD Gene-Disease Associations	1.0	1.27162
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A4AW-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.67327
adrenal_4c	HPA Tissue Sample Gene Expression Profiles	1.0	0.934499
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.00647
GSE139948_3_v_6_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.839915
PI(16:0/22:3(10Z,13Z,16Z))	HMDB Metabolites of Enzymes	1.0	null
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05223
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.896365
PIP2(18:1(9Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
hsa-miR-3714	TargetScan Predicted Conserved microRNA Targets	1.0	0.02226
hsa-miR-362-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.02452
IRF2BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21002
A549_Lomustine_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0210918
MCF7_Cerdulatinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0156409
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.946978
PIP(20:3(8Z,11Z,14Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
GSE175787_11_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NSMF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22122
J82	COSMIC Cell Line Gene Mutation Profiles	1.0	null
layer 2 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21826
LN319	CCLE Cell Line Gene Expression Profiles	-1.0	-1.75054
GTEX-XMK1-0126-SM-4B65F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.88783
ZFYVE16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34811
GTEX-RU72-0326-SM-2TF5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13521
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02964
MCF7_Vandetanib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0114515
Lung adenocarcinoma_LUAD_TCGA-50-5942-01A-21R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
terminal subparaventricular area of THyA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18321
SNU308	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51307
A549_Trichostatin A_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.00931085
SYAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97558
NDUFV3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78213
PI(16:0/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07897
hsa-miR-181d	TargetScan Predicted Conserved microRNA Targets	1.0	0.006367
PIP3(18:1(9Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
hsa-miR-3938	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
TEAD4	ENCODE Transcription Factor Targets	1.0	null
PK45H	CCLE Cell Line Gene CNV Profiles	1.0	2.38869
MED24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84449
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MTX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.002
single-organism metabolic process	GO Biological Process Annotations 2015	1.0	null
hsa-miR-519a	TargetScan Predicted Conserved microRNA Targets	1.0	0.017945
GSE224294_4_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PSMC3IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0606
PIP2(20:4(5Z,8Z,11Z,14Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MS-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2082
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PLZ5-0626-SM-2I5F8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07359
hsa-miR-421	TargetScan Predicted Conserved microRNA Targets	1.0	0.187098
FOXP2	ENCODE Transcription Factor Targets	1.0	null
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PI(18:1(11Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
SLC25A39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15243
GTEX-RWS6-1026-SM-47JXD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36644
A549_Roxadustat_10然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0117524
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.83534
PM20D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16632
FAM111A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94951
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.838358
hsa-miR-548c-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.205675
adrenal gland	HPA Tissue Gene Expression Profiles	1.0	1.00902
HERC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5783
PIP(18:1(11Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
cerebellar cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23742
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5691-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149901_2_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PI(16:0/16:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
MCF7_Luminespib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0140161
MCF7_GSK-LSD1 2HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0215579
GSE157777_2_v_0_foxa3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE221327_5_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.928145
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12114
SARS-CoV NSP16_Day2_None_GSE49263	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.27004
PIP2(18:1(11Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
HOXA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23977
GSE235066_7_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8390679-41467_2021_25186_MOESM5_ESM.xlsx-KDM5B-Unnamed_8_KDM5B	Rummagene Transcription Factor Associations 2026	1.0	null
PI(18:1(9Z)/20:3(8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
A549_Enzastaurin_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0170423
Hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38127
LAMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65455
inner portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19288
hsa-miR-3910	TargetScan Predicted Conserved microRNA Targets	1.0	0.026857
mRNA_MYC_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GSE216273,GSE216292_14_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SEPTIN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68569
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.3277
A549_CUDC-101_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0134874
PI(18:2(9Z,12Z)/22:3(10Z,13Z,16Z))	HMDB Metabolites of Enzymes	1.0	null
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Decitabine_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0108591
PIP2(16:0/22:4(10Z,13Z,16Z,19Z))	HMDB Metabolites of Enzymes	1.0	null
SMAD4	ChEA Transcription Factor Targets	1.0	null
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11009
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.969084
GTEX-Q2AG-0011-R4A-SM-2HMKA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847906
GTEX-XUYS-0008-SM-47JYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.919413
LDHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.77818
liminal alar domain of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23197
hsa-miR-30e	TargetScan Predicted Conserved microRNA Targets	1.0	0.293524
GSE80446_0_v_1_anakinra_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
AP1M2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4219
Perturb_17446_KD_NOX4_SRP290143	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.67175
GSE211128_2_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-490-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
MCF7_Lapatinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0101355
A549_AT9283_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.00897479
GTEX-QMR6-1326-SM-32PLB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19169
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PIP(16:0/22:5(4Z,7Z,10Z,13Z,16Z))	HMDB Metabolites of Enzymes	1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_x_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GEMIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39032
Adrenocortical carcinoma_ACC_TCGA-PK-A5H8-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pallidal amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19203
NCIH727	CCLE Cell Line Gene Expression Profiles	1.0	1.37908
NCIH2066	CCLE Cell Line Gene CNV Profiles	1.0	2.42236
PMC8482521-mmc13.xlsx-Phosphosites_12_hr_48_hr_MLR-Gene_names_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XYKS-0002-SM-4BRWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.976093
FBXW5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30817
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06718
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03239
WIPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23241
TM31	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39374
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30437
Uterus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
estradiol_homo sapiens_gpl570_gse5102	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.993416
ZNF432	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67447
PMC7617064-EMS151900-supplement-Extended_Data_Figure_7_Source_Data.xlsx-D23_NFIA-Logfold_change_threshold_1_0_1_NFIA	Rummagene Transcription Factor Associations 2026	1.0	null
SDF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42023
C32	CCLE Cell Line Gene Expression Profiles	-1.0	-2.27565
Central amygdalar nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04455
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.71777
mantle zone of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54306
PMC12211354-12915_2025_2224_MOESM6_ESM.xlsx-Sheet1-Sheet1_The_source_list_of_zebrafish_Npas4b_targets_from_human_NPAS4_targets_in_CHEA3_database_NPAS4	Rummagene Transcription Factor Associations 2026	1.0	null
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.855482
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.884102
PIP(18:2(9Z,12Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
hsa-miR-548c-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
hsa-miR-141	TargetScan Predicted Conserved microRNA Targets	1.0	0.165047
signal transduction	GO Biological Process Annotations 2015	1.0	null
uterine endometrium	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
A549_Lenalidomide_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0193705
PI(18:0/20:4(8Z,11Z,14Z,17Z))	HMDB Metabolites of Enzymes	1.0	null
PI(16:1(9Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
hsa-miR-98	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
PI(20:4(5Z,8Z,11Z,14Z)/20:0)	HMDB Metabolites of Enzymes	1.0	null
PIP(20:1(11Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
GSE111035,GSE111040_3_v_13_plag1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08443
hsa-miR-3653	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1615
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A624-01A-22R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFJO-0002-SM-3P61X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07314
lymphoblastic leukemia	GWASdb SNP-Disease Associations	1.0	0.437615
mantle zone of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17106
DICER1_KO_GDS4504_582_mouse_bone marrow granulocyte-macrophage progenitors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PIP(20:3(8Z,11Z,14Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
OSC-20	COSMIC Cell Line Gene CNV Profiles	1.0	2.19301
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
PMC7862469-13238_2020_779_MOESM4_ESM.xlsx-FOXO3-GE_VS_WT-Symbol_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.975096
MCF7_SRT1720 HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0141687
A549_UNC1999_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0195022
PI(22:3(10Z,13Z,16Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
PIP(18:0/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
TMEM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57321
STAT3	ChEA Transcription Factor Targets	1.0	null
PI(16:1(9Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.57138
GSE135705_5_v_3_corticosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HT1376	CCLE Cell Line Gene Expression Profiles	1.0	2.05798
Lung adenocarcinoma_LUAD_TCGA-62-A46V-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE81803,GSE81912_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Fluorouracil_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0146644
r1 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.9759
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1Z4-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RTLS-2326-SM-46MUH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953973
PIP(16:0/22:2(13Z,16Z))	HMDB Metabolites of Enzymes	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8519-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058537
PIP2(16:0/22:3(10Z,13Z,16Z))	HMDB Metabolites of Enzymes	1.0	null
TMED9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85557
A549_SB431542_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.013605
GSE160817_7_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Accessory facial motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3526
GTEX-REY6-1026-SM-2TF4Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98979
hsa-miR-548ac	TargetScan Predicted Conserved microRNA Targets	1.0	0.02226
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5890-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8387919-mmc2.xlsx-ST6_NEUROG3-KO_downreg-Unnamed_4_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_Glesatinib(MGCD265)_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0172125
GSE158182_5_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2967-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHH2	CCLE Cell Line Gene Expression Profiles	1.0	1.67252
GGTLC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63979
cerebellar cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02155
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.39658
MCF7_ITSA-1_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0258645
SIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56181
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.114999
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.104
CENPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87922
LXF-289	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNU869	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5476
PI(20:4(5Z,8Z,11Z,14Z)/20:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
superficial stratum of PaS (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21915
496100463_FWM_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.24142
A549_Sodium Phenylbutyrate_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.019089
DPP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51487
GTEX-XPVG-0726-SM-4B658	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924265
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37911
PRKACG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56549
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7897-01A-21R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4494	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
PNN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61289
GTEX-S7SE-0005-SM-2XCEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01351
H3K4me1_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
horizontal nucleus of the diagonal band	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24746
RBM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9504
MCF7_SL-327_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0270396
hsa-miR-520d-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
RPS24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87318
SNU761	CCLE Cell Line Gene Expression Profiles	1.0	1.39172
GSE227592_2_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17335
GSE180185_4_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_Cerdulatinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.020719
GTEX-T5JW-0003-SM-3NMAD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.956384
GTEX-XV7Q-0726-SM-4BRV6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932999
PI(22:4(7Z,10Z,13Z,16Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
GSE225869_3_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PEDS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65268
CELSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58066
HDQP1	CCLE Cell Line Gene CNV Profiles	1.0	1.51553
MCF7_Triamcinolone Acetonide_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0334703
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_JNJ-26854165_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0204215
GTEX-U3ZG-0001-SM-47JYF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05622
MCF7_Curcumin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0183581
NCI-H196	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE150669_2_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JN-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FGF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42503
Flocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17493
BCAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73787
GTEx AdiposeTissue 20-29 vs 40-49	GTEx Tissue-Specific Aging Signatures	1.0	5.75431
hsa-miR-1226	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
MARVELD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50877
hsa-miR-136	TargetScan Predicted Conserved microRNA Targets	1.0	0.002088
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05722
PIP3(18:1(11Z)/20:3(8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
PIP2(20:4(8Z,11Z,14Z,17Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PI(18:1(11Z)/20:4(5Z,8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
GTEx AdiposeTissue 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	1.0	5.29507
GTEX-S4Q7-0003-SM-3NM8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22003
GOLT1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24781
Lung adenocarcinoma_LUAD_TCGA-91-6831-11A-02R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUZ12-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SETDB1-19884257-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SPATA2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24518
GSE210101,GSE210114_4_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
A549_SRT2104_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0294035
CHAF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03086
basal part of terminal hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36388
A549_2-Methoxyestradiol_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0262444
DU 145	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.824536
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6030-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3731-11A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
INPP5E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06443
FOXA2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TMMY-1726-SM-4DXTD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3336
GSE210101,GSE210114_5_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
CAND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5071
PMC9424213-41467_2022_32537_MOESM5_ESM.xlsx-HeLa_IER3-AS1sh_DEGs-DEGs_in_HeLa_IER3-AS1sh_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.69601
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
A549_SRT2104_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0269886
H3K4me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
striohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21279
PIP(20:3(8Z,11Z,14Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_12180_KD_METTL3_ERP137121	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.01884
layer II of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.932165
sevoflurane_homo sapiens_gpl570_gds2772	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.896365
Tobacco Use Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
NCIN87	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7546
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.85091
IZUMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07647
HS 852.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44632
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PIP(18:3(9Z,12Z,15Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
CXADR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76287
H3K27me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4729	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
MCF7_JNJ-26854165_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0159697
MCF7_Toremifene Citrate_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0162143
r1 part of intermediate nucleus of the lateral lemniscus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26829
PIP2(18:1(9Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
GTEX-QMRM-0008-SM-447B1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
GSE158320,GSE183351_2_v_3_lin28b_human	RummaGEO Gene Perturbation Signatures	1.0	null
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.5768
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62899
PIP2(18:0/20:4(5Z,8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QCQG-1426-SM-48U22	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60294
GTEX-T6MN-2526-SM-32PMN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834961
hsa-miR-4762-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.029271
Midbrain reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49352
RABEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46545
GSE145990_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Subpallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.995
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5636-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.3368
PMC7335061-41467_2020_17150_MOESM4_ESM.xlsx-Table_S3-LIN28B_correlates_LIN28B	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PI(20:4(8Z,11Z,14Z,17Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K9me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RPS6KB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21915
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
A549_Navitoclax_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0190306
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-ensembl_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SIHA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XQ3S-0001-SM-4B64K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
GSE205730,GSE205731_2_v_0_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GATA5_KO_GDS4809_170_mouse_Lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-RWSA-0626-SM-2XCBD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11952
hsa-miR-519e	TargetScan Predicted Conserved microRNA Targets	1.0	0.034317
GTEX-XLM4-2926-SM-4AT59	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897944
Lung adenocarcinoma_LUAD_TCGA-55-8299-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PI-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_iPS-15b	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157F_vs_MSX1-Gene_name_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32573
GTEX-T5JC-0001-SM-3NMAK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42172
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.854407
HTT-18923047-STHdh-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0664
CERS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2097
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.45512
CTCF_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE133087_1_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE256181_1_v_0_etv2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16783
hsa-miR-2277-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GPR108	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44459
hsa-miR-124	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PI(20:0/20:3(8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A549_Ofloxacin_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0199649
TCCSUP	CCLE Cell Line Gene CNV Profiles	1.0	1.434
LASV_FML29 _4hr_24069471_GSE41300	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.11711
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50889
GTEX-X5EB-0008-SM-46MU3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.968516
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CALML6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33064
hsa-miR-570	TargetScan Predicted Conserved microRNA Targets	1.0	0.075559
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47529
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
RABGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.90801
PI4KA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26115
PIP2(16:2(9Z,12Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
Ar	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.2143
GTEX-X4XX-0011-R8B-SM-46MWM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879783
TOR3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46326
RAB11FIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30184
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SNU668	CCLE Cell Line Gene Expression Profiles	1.0	1.54699
H3K4me3_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EBPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47
Lake et al.Science.Ex4_Brain_Human	CellMarker Gene-Cell Type Associations	1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
NSUN5P2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68219
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SNRPB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13258
H3K9ac_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PIP(18:1(11Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
PMC4904359-12915_2016_267_MOESM12_ESM.xlsx-ARGFX_DOWN-All_significantly_up_regulated_genes_determined_by_DESeq2_fold_change_greater_than_1_25_going_down_from_an_FPKM_of_at_least_2_ARGFX	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_11492_OE_Tnfsf15_SRP106312	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.3925
SW756	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WWYW-0011-R11A-SM-3NB38	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55813
PCNX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41109
Inferior salivatory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06212
GSE229978_4_v_1_morphine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EEF1AKMT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88869
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-OLIG2_UNIQUE_DYS_GENES-NEUN_TLE_vs_TL_log2FoldChange_1_padj_0_1_OLIG2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-PAX6_UNIQUE_DYS_GENES-PAX6_TLE_vs_TL_log2FoldChange_1_padj_0_1_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3247
TOP2B-26459242-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PIP3(18:1(9Z)/20:3(8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
GSE150055_0_v_2_melphalan_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RUFY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35245
PIP2(22:2(13Z,16Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
HPAC	CCLE Cell Line Gene CNV Profiles	1.0	1.39245
PIP3(16:0/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
19190338-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
MCF7_MK-0752_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0129412
CDIPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68335
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PIP2(18:1(11Z)/20:4(8Z,11Z,14Z,17Z))	HMDB Metabolites of Enzymes	1.0	null
ATM_KD_GSE54268_663_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6164
PIP2(18:1(11Z)/20:3(5Z,8Z,11Z))	HMDB Metabolites of Enzymes	1.0	null
THOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11415
GSE146982_4_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-759	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
PNLDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26141
TCF12	ENCODE Transcription Factor Targets	1.0	null
PIP2(18:2(9Z,12Z)/20:0)	HMDB Metabolites of Enzymes	1.0	null
hsa-let-7f	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
Spi1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	62.0121
CCAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66246
GSE143847_2_v_3_inhba_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.881086
lateral preoptic area, PO1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56581
lateral part of m2A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.97541
RPL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72383
primary auditory cortex (core)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.949968
MCF7_Meprednisone_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0145656
Brain Lower Grade Glioma_LGG_TCGA-HT-7479-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11496110-42255_2024_1140_MOESM3_ESM.xlsx-ST18_Gene_view-Unnamed_1_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
septopallidal part of the olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86922
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.42182
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23815
layer 1 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38987
mantle zone of m2AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.97442
Pancreatic islet cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.523
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.95104
Intercalated nucleus of amygdala	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.943976
MCF7_Toremifene Citrate_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0260082
OV-56	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OHPN-2826-SM-3LK67	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871468
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IN-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-20b	TargetScan Predicted Conserved microRNA Targets	1.0	0.092495
A549_AZ 960_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0175481
GTEX-OIZF-1526-SM-3MJGY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71478
PI(16:0/22:5(7Z,10Z,13Z,16Z,19Z))	HMDB Metabolites of Enzymes	1.0	null
Anterior olfactory nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04796
A_CA_04_2009_7dayMOI-10^6_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.7245
Brain Lower Grade Glioma_LGG_TCGA-HT-7691-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE200673,GSE200691_1_v_0_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XPT6-0226-SM-4B65L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31961
PI(20:3(5Z,8Z,11Z)/20:3(8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
A549_ENMD-2076 L-Tartaric acid_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0112395
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE96649_1_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
lateral preoptic nucleus, PO2 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39846
A549_Amisulpride_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0149302
hsa-miR-1260b	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
CAL-120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.999399
Globus pallidus, internal segment	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42355
GSE226285_3_v_1_nr0b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HLE	CCLE Cell Line Gene CNV Profiles	-1.0	-2.74331
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2821-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_AG-14361_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0126786
irinotecan_rattus norvegicus_gpl1355_stomach_gds3466	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-T5JC-2326-SM-32PMR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98997
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.06924
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.885631
HO-1-U-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.19301
GTEX-Q2AI-0008-SM-48U2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06099
GTEX-P78B-0426-SM-2I5F5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01767
RFC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71087
peripheral nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.252919
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00634
A549_Roxadustat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0171621
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-PAX6_UNIQUE_DYS_GENES-NEUN_TLE_vs_TL_log2FoldChange_1_padj_0_1_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
ventral nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55825
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.881747
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.839915
GTEX-R55C-0008-SM-48FCF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04802
Hmx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.4699
RHOBTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72479
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SEPHS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4017
PI(18:1(11Z)/20:3(8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATR_KD_GSE54268_664_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC12867126-NIHMS2139346-supplement-Supplementary_Table_S1.pdf-46-ZNF410_ZNF410	Rummagene Transcription Factor Associations 2026	1.0	null
KCNIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.92743
r1 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39974
SUZ12	ENCODE Transcription Factor Targets	1.0	null
CCNG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84334
PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
striatum_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.919861
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ventral group of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40438
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-520e	TargetScan Predicted Conserved microRNA Targets	1.0	0.056784
FBH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97042
tail of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.42945
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_7782_KD_ASCC3_SRP023199	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.31911
GLC82	CCLE Cell Line Gene CNV Profiles	1.0	2.57744
MCF7_PCI-34051_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0157895
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
REST-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC11328671-jitc-12-4-s003.pdf-314-PLAGL2_PLAGL2	Rummagene Transcription Factor Associations 2026	1.0	null
VZ in midcingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.872865
MCF7_Amisulpride_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0175408
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-WHPG-0004-SM-3NMDO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02251
PI(18:0/20:4(5Z,8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
PI(16:0/16:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
PAGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95734
PMC11839389-PUL2-15-e70058-s003.xlsx-FLF_TBX4_mergeRNAseqChIPseq-symbol_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ESCO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61561
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7928
Parvicellular reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03765
GTEX-PWOO-0008-SM-48TDU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
NDOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70715
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellum	HPA Tissue Protein Expression Profiles	1.0	1.00026
Lung adenocarcinoma_LUAD_TCGA-50-8460-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE262134_0_v_1_dnajc12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_Celecoxib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.015989
PI(18:3(6Z,9Z,12Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
A549_JQ1_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0198457
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_id_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_13935_KO_MYT1_SRP187954	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
ZNF280C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16951
GTEX-SUCS-0002-SM-3NMAJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47933
schizophrenia	GWASdb SNP-Phenotype Associations	1.0	0.595442
VZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.41588
Phospholipase C, phosphatidylinositol-specific , X domain	InterPro Predicted Protein Domain Annotations	1.0	null
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2292
Bladder Urothelial Carcinoma_BLCA_TCGA-FT-A3EE-01A-11R-A206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S341-0726-SM-4AD5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31606
CHD7	ENCODE Transcription Factor Targets	1.0	null
GSE44157,GSE44163_1_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_KW-2449_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0161625
PIP2(18:1(9Z)/18:3(6Z,9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
PIP3(16:0/16:0)	HMDB Metabolites of Enzymes	1.0	null
PI(20:4(8Z,11Z,14Z,17Z)/20:0)	HMDB Metabolites of Enzymes	1.0	null
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.41001
GSE146612_1_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9387164-Table_2.XLSX-Sheet1-CLOCK_CLOCK	Rummagene Transcription Factor Associations 2026	1.0	null
RPS17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.645
GTEX-QV44-0008-SM-447AX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01287
ORMDL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00071
GSE221327_4_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH1915	CCLE Cell Line Gene CNV Profiles	-1.0	-1.82581
HCC1954	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.993441
PI(22:4(10Z,13Z,16Z,19Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
A549_PFI-1_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0130973
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3387-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6983-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056133
GTEX-QDT8-0426-SM-32PKZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06322
GTEX-PWCY-0008-SM-48TE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30584
H3K27me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE79663_2_v_0_tcf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.77942
PMC11801220-NIHMS2038999-supplement-14.xlsx-Exc-SKOR2-gene_SKOR2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Human - Adipose - L2 - hEndoS2	HuBMAP Azimuth Cell Type Annotations	1.0	null
GTEX-WFON-0226-SM-3GIKR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4678
GTEX-PX3G-2426-SM-48TZZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964608
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NAA10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50692
MIOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54914
GTEX-NL4W-0011-R11A-SM-2I3DW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18427
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039632
ZKSCAN1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AP-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_UNC0379_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0406804
SLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61452
NCI-H64	COSMIC Cell Line Gene CNV Profiles	1.0	2.19301
COX7A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40733
MYC_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of isBI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.01231
cerebellar cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.61102
PI(20:1(11Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
GTEX-NPJ7-2826-SM-2I3FU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990066
GSE202434,GSE202438_13_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12229924-ab-24-0861-Supplementary-3.pdf-7-DMRT2_DMRT2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.864185
hsa-miR-30d	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
hsa-miR-181b	TargetScan Predicted Conserved microRNA Targets	1.0	0.009975
NCC021	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ECE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.744
LONP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45774
GTEX-U3ZH-0008-SM-4DXT2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBC1D15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52284
Anterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04174
PIP2(16:0/22:5(7Z,10Z,13Z,16Z,19Z))	HMDB Metabolites of Enzymes	1.0	null
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-35-3615-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE183335,GSE183351_3_v_2_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH2452	CCLE Cell Line Gene Expression Profiles	1.0	1.76673
A549_CEP-33779_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0254801
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.3926
GSE125862_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pituitary gland tumor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.759
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15064
ABHD17A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44109
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3646	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
GSE158431_2_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PVOW-0008-SM-48TE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02737
GSE225869_2_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	1.0	null
TMEM138	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31768
Sarcoma_SARC_TCGA-DX-A6Z2-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
psychotic disorder	GWASdb SNP-Disease Associations	1.0	0.283083
TE-10	COSMIC Cell Line Gene CNV Profiles	1.0	2.19301
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SFXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85499
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
ZNF527	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55249
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02858
sensory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.485545
Ectoderm differentiation	WikiPathways Pathways 2024	1.0	null
A549_Fulvestrant_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0157669
ARAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14169
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14031
GTEX-QEG4-0008-SM-48TYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03982
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of mammary gland_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE182921_0_v_1_slit2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.868204
PMC7594423-12915_2020_895_MOESM13_ESM.xlsx-Table_S6D-Table_S6D_-_Differentially_Expressed_genes_shared_between_BRCA_TRIM25_amp_and_STAD_CIC_Del_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39846
PMC5303304-13073_2017_407_MOESM5_ESM.xlsx-mycn-sy5y-se_single_24DMSO_vs_4-Table_S4_Genes_differentially_expressed_by_48h_Dox_MYCN_overexpression_treatment_DE_comparison_with_SY5Y-MYCN_control_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE150055_0_v_1_melphalan_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KW-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Esophagus - Muscularis	GTEx Tissue Gene Expression Profiles 2023	1.0	3.26861
Perturb_4877_OE_BANCR_SRP135857	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.5963
MCF7_Aminoglutethimide_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0121569
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4622-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TMZS-0001-SM-3P61Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45139
PIP2(18:2(9Z,12Z)/20:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
MRPL34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30043
PIP2(18:0/16:0)	HMDB Metabolites of Enzymes	1.0	null
GSE138001_2_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mantle zone of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16312
GTEX-QLQ7-0526-SM-2I5G3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23543
PIP2(16:0/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
ZW10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28184
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.926102
intermediate stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08142
CETN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06478
PI(20:3(5Z,8Z,11Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
18338247-SuppTable4B	GeneSigDB Published Gene Signatures	1.0	null
superficial stratum of r1BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26858
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.686183
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PI(20:3(5Z,8Z,11Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
GTEX-SNOS-0008-SM-4DM6I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
ACYP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02985
phosphoric ester hydrolase activity	GO Molecular Function Annotations 2015	1.0	null
MCF7_Mesna_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0184757
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7795
inner SZ in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.898176
molecular_function	GO Molecular Function Annotations 2015	1.0	null
GSE213228_4_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TMEM60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8024
intermediate stratum of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78971
PI(22:4(7Z,10Z,13Z,16Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
Congenital adrenal insufficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
GSE205163,GSE205164_3_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7585942-mmc5.xlsx-RBM10_OE_upregulated-Supplementary_Table_S5_RBM10-mediated_gene_expression_changes_in_BEAS-2B_and_PC9_cells_Cutoff_P_0_05_log2FoldChange_1_KD_knockdown_OE_overexpression_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SF3A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86295
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.5863
parabrachial part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01183
episupraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17925
GSE94814_1_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_SRT2104_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0173985
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HNF1B_HNF1B	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
GRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87843
PI(22:2(13Z,16Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5VV-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CENPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15437
SUZ12_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0634
Perturb_17943_KO_Stag1_SRP044099	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.54582
PI(18:0/20:2(11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
ZNF189	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4205
PIP(16:2(9Z,12Z)/22:3(10Z,13Z,16Z))	HMDB Metabolites of Enzymes	1.0	null
GTEX-XMD1-0011-R11A-SM-4AT5J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14713
PDCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82919
MCF7_Sorafenib Tosylate_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0304583
liminal part of alar r1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62899
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.833199
ChIP_K27me3_17603471_mouseMEF	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PIP2(18:0/18:3(9Z,12Z,15Z))	HMDB Metabolites of Enzymes	1.0	null
RCN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20589
PIP(18:1(11Z)/20:4(5Z,8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
GTEX-RU1J-0826-SM-46MUU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0195
GTEX-R53T-0008-SM-48FEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840912
PMC12616242-can-24-3452_supplementary_table_s4_suppst4.xlsx-EWSR1-FLI1-KDM6B_genes-Genes_associated_to_EWSR1_FLI1-KDM6B_peaks_in_A-673_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_Panobinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00683145
cerebellar cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.79467
PI(22:2(13Z,16Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
647V	CCLE Cell Line Gene CNV Profiles	1.0	1.35631
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE217452_3_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYLA	DepMap CRISPR Gene Dependency	1.0	2.13832
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
TEX30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40798
GTEX-RTLS-0826-SM-2TF5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89346
Inflammation	CTD Gene-Disease Associations	1.0	1.21727
BEX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88849
heart muscle	HPA Tissue Gene Expression Profiles	1.0	1.45012
HENMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39744
GSE148200_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Bipolar Disorder	DisGeNET Gene-Disease Associations	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_1h-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81R-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WHWD-0326-SM-3LK6L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09206
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17292
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39W-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.282
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R45C-0926-SM-3GAD4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910747
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-version_2_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
UACC-812 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.157
PMC7617064-EMS151900-supplement-Extended_Data_Figure_7_Source_Data.xlsx-D23_NFIX-Logfold_change_threshold_1_0_1_NFIX	Rummagene Transcription Factor Associations 2026	1.0	null
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11214527-mmc5.xlsx-ADNP-gene_ADNP	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF491	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11643
hsa-miR-548l	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
Perturb_462_KO_RUVBL1_SRP241670	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.69775
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5878-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE109565_12_v_11_glyphosate_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.15117
cancer	GWASdb SNP-Disease Associations	1.0	0.061365
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.036713
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PIP(20:3(8Z,11Z,14Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2807-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Arx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.2235
hsa-miR-3688-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.003282
ZBTB47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02154
PIP(16:0/22:4(10Z,13Z,16Z,19Z))	HMDB Metabolites of Enzymes	1.0	null
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11456
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GW-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-V1D1-0526-SM-4JBGW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10225
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5882-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PI(18:0/18:3(6Z,9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
SW 480	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.915717
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
PHF8	ENCODE Transcription Factor Targets	1.0	null
PIP2(18:1(9Z)/20:4(8Z,11Z,14Z,17Z))	HMDB Metabolites of Enzymes	1.0	null
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.44899
A549_Ofloxacin_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0317366
PMC7176284-pcbi.1007753.s008.xlsx-2_MYCN-NA_NBL_Multimodal_Genes-gene_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7473-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RU72-0226-SM-46MUD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842648
GTEX-OHPM-0008-SM-4E3IP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01598
YBEY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6745
PIP(22:4(10Z,13Z,16Z,19Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
CLIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79511
A549_Danusertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0175522
mantle zone of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27126
GSE234514,GSE234516_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_SB431542_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0221714
NUP58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07763
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A8BQ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_JNJ-26854165_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0256294
PMC9564215-pnas.2203480119.sd02.xlsx-OVCAR-5_SCD_KD_cultured_in_low-hgnc_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
isthmic basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61306
JUN	JASPAR Predicted Transcription Factor Targets	1.0	null
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9512
H3K4me1_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HW-7493-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZKSCAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20907
GTEX-XV7Q-0826-SM-4BRV7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3926
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.82572
Sporadic Cjd	DisGeNET Gene-Disease Associations	1.0	null
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
SETD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33744
FRS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5715
uterus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06856
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TR-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.0581
A549_PHA-680632_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0241503
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
MCF7_INO-1001_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0266205
paracentral lobule, anterior part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.886877
A549_Valproic acid sodium salt_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0154649
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.03319
MCF7_PCI-34051_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.025026
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06245
EGFR_druginhibition_82_GSE27638	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.67738
184A1N4	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.844558
lateral part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.46214
GSE77178_2_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HMG20B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91977
GTEX-TSE9-2226-SM-4DXUR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16546
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07623
VZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26234
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33578
DDHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56668
PI(16:0/20:4(8Z,11Z,14Z,17Z))	HMDB Metabolites of Enzymes	1.0	null
Perturb_8305_KO_GALNT1_ERP012063	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Necrosis	CTD Gene-Disease Associations	1.0	1.4202
Perturb_8970_KD_UCA1_SRP068139	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_8967_KD_CAPERa_SRP068139	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
PKDCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07784
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28324
FOXP2_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PIP2(20:3(8Z,11Z,14Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
PIP2(18:0/18:3(6Z,9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
PPP1R3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96708
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11246
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01676
GTEX-SUCS-0008-SM-4DM53	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0435
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RABL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25272
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7412812-13059_2020_2115_MOESM11_ESM.xlsx-All_SUZ12-Upregulated_in_SERBP1_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892936
GSE211128_2_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888472
GTEX-U3ZN-2526-SM-3DB7V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956155
hsa-miR-1247	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_7872_KD_MYO6_SRP258737	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
ZFAND4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80707
PI(18:1(11Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
FOXO1_KD_GDS2720_478_mouse_LSK	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
A549_Ruxolitinib_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0173475
GTF2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68862
MDAMB436	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63063
RPL35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48372
hsa-miR-2052	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
GSE214583,GSE214585_1_v_0_steap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PIP(16:0/20:3(5Z,8Z,11Z))	HMDB Metabolites of Enzymes	1.0	null
hsa-miR-1273f	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
HEC50B	CCLE Cell Line Gene CNV Profiles	-1.0	-2.15287
Perturb_7894_KD_TEX10_SRP321656	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
PI(16:0/20:4(5Z,8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
GSE133764_2_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
PIGC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66355
hsa-miR-93	TargetScan Predicted Conserved microRNA Targets	1.0	0.09606
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7245-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMAD3-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MCF7_SL-327_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0363742
HCC70	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.40471
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nerve Degeneration	CTD Gene-Disease Associations	1.0	1.04465
GTEX-POMQ-0008-SM-48TE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09271
abnormality of immune system physiology	GWASdb SNP-Phenotype Associations	1.0	0.099645
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.7976
ADGRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64942
Entorhinal area, medial part, dorsal zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.94393
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25331
MCF7_SRT2104_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0154545
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.7445
EPS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02653
GATA5_KO_GSE47425_386_mouse_lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-WY7C-1126-SM-3NB3A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40907
GSE148200_0_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4217-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIP(22:5(4Z,7Z,10Z,13Z,16Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.993643
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
H3K9me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PI(18:0/20:3(5Z,8Z,11Z))	HMDB Metabolites of Enzymes	1.0	null
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PIP2(18:1(11Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
GTEX-XUJ4-0526-SM-4BOON	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37677
A549_ITSA-1_10然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0162566
496100322_FWM_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.19981
MCF7_Disulfiram_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0120683
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
MCF7_Navitoclax_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0242283
PI(16:0/18:0)	HMDB Metabolites of Enzymes	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.378
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-7338-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.870915
GTEX-QDVN-0326-SM-2I3FS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02965
Nfatc1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.4799
adrenal_4d	HPA Tissue Sample Gene Expression Profiles	1.0	1.06845
H3K4me1_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
IKZF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09307
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.925321
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58764
PIP2(20:2(11Z,14Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
PI(20:1(11Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
HPCAL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97695
Brain Lower Grade Glioma_LGG_TCGA-P5-A731-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIP2(22:3(10Z,13Z,16Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
hsa-miR-1178	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_name_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
VZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.32959
PI(18:2(9Z,12Z)/20:2(11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
PIP(18:3(6Z,9Z,12Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
GTEX-X5EB-0004-SM-46MWA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.966059
Perturb_4876_KD_BANCR_SRP135857	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.88719
SK-MG-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.19301
TRIM24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7488
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4903
CDC45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51677
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.880836
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
ARHGAP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89471
hsa-miR-548a-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.029271
preisthmic midbrain tectum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50769
A549_Fasudil_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0155357
periventricular stratum of Ist	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.98705
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14802
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.839915
PIP(16:0/20:4(8Z,11Z,14Z,17Z))	HMDB Metabolites of Enzymes	1.0	null
GTEX-QEG4-0426-SM-33HC3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03141
hsa-miR-603	TargetScan Predicted Conserved microRNA Targets	1.0	0.026857
HBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34311
GTEX-WK11-0626-SM-3NMAV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21818
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
A549_Iniparib_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0120962
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43125
hsa-miR-4456	TargetScan Predicted Conserved microRNA Targets	1.0	0.248923
TSC22D4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27262
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4864-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XOTO-2926-SM-4B65G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94413
POU2F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88771
ventrolateral part of isA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14333
GSE158458_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ChIP_SUZ12_16625203	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE149870_0_v_1_pfn1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dorsal motor nucleus of the vagus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.840225
GTEX-QVJO-0008-SM-447AU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.968667
GSE77108_6_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10568675-JCMM-27-3157-s003.docx-38-HES1_HES1	Rummagene Transcription Factor Associations 2026	1.0	null
RBM41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50207
KON	COSMIC Cell Line Gene CNV Profiles	1.0	2.19301
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_AZ 960_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0214422
MFHAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40813
GTEX-Q2AG-2826-SM-2HMJQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978794
GTEX-QV31-0008-SM-447AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.937107
PMC11669947-JCSM-16-e13672-s001.pdf-59-PRDM6_PRDM6	Rummagene Transcription Factor Associations 2026	1.0	null
PI(20:3(5Z,8Z,11Z)/20:3(5Z,8Z,11Z))	HMDB Metabolites of Enzymes	1.0	null
TMEM125	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.896
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-WZTO-1326-SM-3NM8X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0274
hsa-miR-1252	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
BLM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23343
VZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.98366
hsa-miR-3652	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GSE213632_3_v_6_acod1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146612_1_v_3_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CORT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89526
A549_2-Methoxyestradiol_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.027777
GTEX-T2YK-0008-SM-4DM6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04964
KDM5B	ENCODE Transcription Factor Targets	1.0	null
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-188-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.219115
RAD50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03267
HMGCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90213
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
A4 noradrenergic cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64631
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Linifanib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0117473
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CHK2_KD_GSE54268_668_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-P4PP-3026-SM-3P61O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23278
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81T-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SAMM50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79697
NCI-H650	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE206400_1_v_0_nusinersen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PIP(18:2(9Z,12Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
H3K4me1_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC9253713-mmc3.xls-sufu_KD_HCC1954_DEGs-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
HOXC9-25013753-NEUROBLASTOMA-BE2-C-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-655	TargetScan Predicted Conserved microRNA Targets	1.0	0.212286
SLC16A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.31552
PMC11544636-CCS3-18-e12047-s001.xlsx-Supplementary_Table_S2-Supplementary_Table_S2_554_differentially_expressed_genes_between_DOX_and_CTR_D0_in_A673pTERshEWS_FLI1_model_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PIP2(16:0/18:0)	HMDB Metabolites of Enzymes	1.0	null
mantle zone of Ist	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33848
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.836034
NDUFB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76777
ITPR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50531
GSE225869_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-5R-AA1D-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TGF-beta_OE_GDS2974_137_mouse_corneas	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
496100611_FWM_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.25331
MBD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82097
cervical carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.094218
TBC1D24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55832
A549_Luminespib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0205978
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57612
Paracentral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17508
hsa-miR-135a	TargetScan Predicted Conserved microRNA Targets	1.0	0.026857
MCF7_Fluorouracil_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0320466
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.77416
MEAF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.299
NCI-H1734	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PI(16:0/22:4(10Z,13Z,16Z,19Z))	HMDB Metabolites of Enzymes	1.0	null
A549_Mesna_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.025026
A549_PCI-34051_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0288228
ZNF790	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54608
LPCAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81917
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	67.4446
A549_Tazemetostat_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0227374
GTEX-X8HC-2726-SM-46MUA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923096
CMBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41909
Entorhinal area, medial part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34474
PIP2(18:0/16:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
olfactory receptor neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.979783
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A3JJ-11A-12R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIP2(20:4(5Z,8Z,11Z,14Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
globus pallidus, external segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.66867
18318837-TableS1	GeneSigDB Published Gene Signatures	1.0	null
PI(16:0/20:3(5Z,8Z,11Z))	HMDB Metabolites of Enzymes	1.0	null
GSE227592_0_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
medial superior olive	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.72866
94T778	DepMap CRISPR Gene Dependency	1.0	21.3153
DMKN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1074
SNU878	CCLE Cell Line Gene Expression Profiles	1.0	1.50877
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03239
GTEX-QEG5-0926-SM-2TC64	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935508
immune system cancer	GWASdb SNP-Disease Associations	1.0	0.196765
ZSWIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53152
GTEX-Q2AH-0526-SM-2I3ED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44643
GSE151412_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH1703	CCLE Cell Line Gene CNV Profiles	1.0	1.61034
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23928
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20668
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
GSE201657_0_v_1_ash2l_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE192771_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CPT1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37841
hsa-miR-875-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Lung adenocarcinoma_LUAD_TCGA-44-5644-01A-21R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE174701_4_v_3_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146612_2_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.84466
r6 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12947
GTEX-WH7G-0002-SM-4LVN9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Right atrium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.017
RT-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.779
GTEX-S4P3-0926-SM-4AD54	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48593
CA SKI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.83534
Interbrain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00846
isthmic liminal part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40067
GTEX-QV44-0526-SM-2S1RE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64295
PI(20:3(8Z,11Z,14Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT38_Protein_cis-instrument_MR-eTable_38_Cis-instrument_Mendelian_randomizaion_screen_of_1_901_cortical_proteins_on_lifetime_smoking_behavior_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6932815-ppat.1007634.s015.xlsx-ST5_DGE_ELF1-R8AvIFN48-mock_lfc-ensembl_gene_id_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
PANC0203	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73878
NFIC::TLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.625
posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.953672
superficial stratum of SePal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.88148
RAB8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37667
olfactory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.732677
TCCSUP	CCLE Cell Line Gene Expression Profiles	1.0	1.35149
H3K4me1_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7046-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20449
PI(18:0/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
uterus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PI(18:0/22:4(10Z,13Z,16Z,19Z))	HMDB Metabolites of Enzymes	1.0	null
ZNF165	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69703
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE116492,GSE116495_3_v_1_stag2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Diagonal band nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.11139
Flocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13138
hsa-miR-4299	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
PI(18:1(9Z)/16:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
A549_Pelitinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0158872
A549_Zileuton_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0141679
PMC9380317-13045_2022_1327_MOESM3_ESM.xlsx-Table_S7-Table_S7_Top_500_differentially_modified_gene_bodies_between_MM_and_its_precursors_in_AA_patients_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
H3K27me3_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-let-7b	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.890913
Stereocilium bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.818
Sarcoma_SARC_TCGA-DX-A6BH-01A-12R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Islands of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62925
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
SW 1990	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03239
PIP(20:1(11Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
hsa-miR-4659a-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.017945
intermediate stratum of m2AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81752
cervical cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.102234
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827589
KCTD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22125
GTEX-SIU7-0426-SM-2XCDX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22039
hsa-miR-548q	TargetScan Predicted Conserved microRNA Targets	1.0	0.265648
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NFK9-0926-SM-2HMJU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12331
Metabolite levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.504576
FOXA2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WH7G-0326-SM-3NMBH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27971
GSE211286_1_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.98415
PI(20:0/16:0)	HMDB Metabolites of Enzymes	1.0	null
ZSCAN23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22471
GSE207135_2_v_0_sod2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE108495_1_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PIP[3'](16:0/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
LIN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64045
GSE158431_5_v_7_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PI(20:4(5Z,8Z,11Z,14Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
PI(20:0/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PIP2(20:2(11Z,14Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PI(20:1(11Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
MCF7_Obatoclax Mesylate_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0100327
GTEX-XMK1-0008-SM-4GICF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19859
PI(18:0/22:5(7Z,10Z,13Z,16Z,19Z))	HMDB Metabolites of Enzymes	1.0	null
A549_PHA-680632_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0148572
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FV-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QMR6-0011-R11A-SM-32PKK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86714
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12363
MUTYH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57891
GSE135352_2_v_4_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CAL-85-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.19301
PIP3(16:0/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
EMC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.6493
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Tofacitinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0153733
MCF7_Triamcinolone Acetonide_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0144759
H4C11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85171
ELP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84454
acute leukemia	GWASdb SNP-Disease Associations	1.0	0.663947
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-23c	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
mRNA_ESX1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-Fay_Thermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate stratum of r1BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40036
hsa-miR-520d-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.062888
GSE48812_0_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PLCB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64214
Perturb_529_KO_NFE2L1_SRP333364	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.40073
NB13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mucosa	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
C14orf93	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86564
GTEX-OOBJ-0326-SM-33HBO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15636
intermediate stratum of r5Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59757
GTEX-U3ZM-0008-SM-4DXTQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.949289
SULF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89262
Brain Lower Grade Glioma_LGG_TCGA-DU-A76R-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
periaqueductal gray substance, ventral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.947288
GTEX-TSE9-2926-SM-3DB77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04824
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ETV4_ETV4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-HAND1_neg_targets-Gene_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
periventricular stratum of m2AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.23149
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55F-1226-SM-2TF59	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17467
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1656
UBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00102
OCT4-21477851-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
VZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03069
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04928
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SP-01B-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PI(20:1(11Z)/20:4(8Z,11Z,14Z,17Z))	HMDB Metabolites of Enzymes	1.0	null
GAPDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39396
TRMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.9685
GTEX-UJMC-0008-SM-4IHKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44545
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PIP2(20:1(11Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
SLC23A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79878
metabolic process	GO Biological Process Annotations 2015	1.0	null
PIP2(18:1(11Z)/18:3(6Z,9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
A549_S-Ruxolitinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0135971
ISCU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38008
SUZ12-16625203-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
HERC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19643
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874888
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.37725
GTEX-XK95-0008-SM-4AT5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21254
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_y_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
mRNA_SALL4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GTEX-RWS6-0001-SM-3NMAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02458
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A4-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF317	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5879
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.90369
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.7258
HCC-366	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DU-145	COSMIC Cell Line Gene CNV Profiles	1.0	2.19301
GSE146982_4_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_GSK J1_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.022697
A549_Glesatinib(MGCD265)_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0176293
POR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73268
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4770-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_Ramelteon_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0216075
RC3H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55322
MZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.992776
SMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61464
PI(20:3(5Z,8Z,11Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JW-0008-SM-4DM5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28796
EIF4EBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89926
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UBE2K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62004
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.844885
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.039546
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTF2	ChEA Transcription Factor Targets	1.0	null
PIP(16:0/22:5(7Z,10Z,13Z,16Z,19Z))	HMDB Metabolites of Enzymes	1.0	null
KHK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44642
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1674
NT5C3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95497
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02293
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057229
Perturb_7666_KD_IMP1_DRP003316	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.50585
hsa-miR-548h	TargetScan Predicted Conserved microRNA Targets	1.0	0.205675
496100330_PCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.11499
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11615365-41467_2024_54246_MOESM5_ESM.xlsx-RT112-Numb-KD_vs_Ctr-KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SLC25A51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92592
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PI(20:3(8Z,11Z,14Z)/20:3(5Z,8Z,11Z))	HMDB Metabolites of Enzymes	1.0	null
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34256
PIP3(18:1(11Z)/20:3(5Z,8Z,11Z))	HMDB Metabolites of Enzymes	1.0	null
r7 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14779
LRRC47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31988
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.05732
H3K4me1_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE193402_0_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mantle zone of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76828
PMC7412812-13059_2020_2115_MOESM11_ESM.xlsx-All_EZH2-Upregulated_in_SERBP1_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PI(18:3(9Z,12Z,15Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE223241_1_v_3_cdkn2a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4311	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.955828
A549_Roxadustat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0157886
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0467
hsa-miR-183	TargetScan Predicted Conserved microRNA Targets	1.0	0.02452
PIP2(20:3(5Z,8Z,11Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
hsa-miR-1224-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
hsa-miR-524-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
NLGN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1096
GSE202434,GSE202438_4_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7064337-elife-51373-supp1.xlsx-SUZ12_targets_shPHF19-List_of_567_genes_marked_by_SUZ12_ChIPseq_iafter_PHF19_KD_shPHF19_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GLIS3_KO_GDS3812_500_mouse_Embryonic pancreas at E15.5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE213228_4_v_3_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FAM117A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29822
GSE242333_0_v_2_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3255	COSMIC Cell Line Gene CNV Profiles	1.0	2.19301
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
HELA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.8123
GTEX-S3XE-0008-SM-3NM8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.886798
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A549_BMS-265246_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0153523
GTEX-O5YU-0008-SM-4E3I7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836394
Anxiety Disorders	CTD Gene-Disease Associations	1.0	1.3314
Perturb_10327_KO_Anxa1_SRP377197	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.26306
A549_Belinostat_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0116247
SEC11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01902
18006812-TableS4	GeneSigDB Published Gene Signatures	1.0	null
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.50521
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47529
VI, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.850928
ZNF473	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64148
parasubiculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21973
MCF7_BMS-265246_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00881882
MDS - Myelodysplastic syndrome_Bone marrow stem cell_GSE4619	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.329
ILK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7787
LUDLU1	DepMap CRISPR Gene Dependency	1.0	2.95183
SOX3-22085726-MUSCLE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-3137	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
SETD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57249
Yy1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.5768
dorsalstriatum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.871608
r7 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42832
superficial stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.0618
647-V	COSMIC Cell Line Gene CNV Profiles	1.0	2.19301
intermediate stratum of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.44771
Creb3l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.39
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral group of nuclei, left, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08325
GTEX-UPK5-0326-SM-3GAF3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19387
mantle zone of m2B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60564
NFXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30766
GSE111660_4_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.0405
HDAC2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XX-1126-SM-3NMBY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03195
phosphoric diester hydrolase activity	GO Molecular Function Annotations 2023	1.0	null
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44807
ChIP_EZH2_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-HAND1_neg_targets-ID_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate stratum of m2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14653
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Fatty Liver	CTD Gene-Disease Associations	1.0	1.12872
STAT3	JASPAR Predicted Transcription Factor Targets	1.0	null
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.31444
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6936-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DICER1_KO_GDS4504_585_mouse_bone marrow granulocyte-macrophage progenitors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
A549_PCI-34051_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0249661
layer 2 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43191
DAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53379
GLRX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50603
GTEX-PWN1-2426-SM-48TDD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05425
GSE212848_1_v_0_pum1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE138001_2_v_3_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE175787_11_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.07862
A549_ITSA-1_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.021017
GTEX-WY7C-0526-SM-3NB3D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47016
Entorhinal area, medial part, dorsal zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13602
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.29968
GTEX-QCQG-0008-SM-48U2G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.939095
rostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29396
CP66-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Small intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
A549_WP1066_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0224511
ZNF226	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35431
SRPRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51216
DALRD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.76292
NCIH196	CCLE Cell Line Gene CNV Profiles	1.0	1.3624
H3K27me3_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Sorafenib Tosylate_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0242048
PPP4R3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69155
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.2947
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31871
496100390_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.03198
PI(18:0/18:3(9Z,12Z,15Z))	HMDB Metabolites of Enzymes	1.0	null
PIP2(16:0/20:4(5Z,8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
PECAPJ49	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51526
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.79638
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10794847-mmc5.xlsx-PIAS1_KD_up-Table_S4_Differentially_expressed_genes_with_PIAS1_knockdown_in_the_progenitors_state_Related_to_Figure_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE157555,GSE157556_0_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ovary_8a	HPA Tissue Sample Gene Expression Profiles	1.0	1.4851
H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PIP(22:2(13Z,16Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
cervical cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.099286
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A2C5-01A-12R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Complete androgen insensitivity syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.43
A549_BMS-911543_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0148331
heart_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.40818
DMRTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34985
MCF7_Motesanib Diphosphate_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0205304
GTEX-T6MN-0926-SM-32PLX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871795
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051746
PI(18:2(9Z,12Z)/22:2(13Z,16Z))	HMDB Metabolites of Enzymes	1.0	null
SOX14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99352
A549_Ofloxacin_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0225561
SKMEL2	CCLE Cell Line Gene CNV Profiles	-1.0	-2.00717
KANSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01482
A549_PCI-34051_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0196237
PIP2(18:0/20:3(8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
GSE174418,GSE174421_2_v_3_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_Tofacitinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.022772
mantle zone of SePal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67165
PYCR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1783
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
rostral ventrolateral reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08789
hsa-miR-200a	TargetScan Predicted Conserved microRNA Targets	1.0	0.17031
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC13138062-mmc7.xlsx-DUGs_E2F1_targets-DUGs_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S7SF-0526-SM-3K2BC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10996
GTEX-XBED-0526-SM-47JY3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3924
GTEX-S4Z8-2026-SM-3K2A9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865845
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24361
hsa-miR-642a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
hsa-miR-548i	TargetScan Predicted Conserved microRNA Targets	1.0	0.226173
PMC6137307-mmc2.xlsx-IRF9-IFNa-Table_S1_IRF9-IFNa_Related_to_Figure_1_IRF9	Rummagene Transcription Factor Associations 2026	1.0	null
HS578T	CCLE Cell Line Gene CNV Profiles	-1.0	-2.43031
PIP3(18:0/16:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
disease	GWASdb SNP-Disease Associations	1.0	0.04471
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02131
GTEX-XUW1-0126-SM-4BOOQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09129
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.984492
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-A5FZ-01A-31R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GN-06A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-8007-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.843177
SF3B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4498
r2 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22423
PI(16:2(9Z,12Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
CDK5RAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49898
mRNA_SOX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GSE195514_0_v_1_stk25_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Transitional cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.691
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LCLC-103H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05767
GTEX-R55E-0011-R11A-SM-2TC6I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4977
ABC-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.19301
PIP(18:1(9Z)/20:4(5Z,8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
GSE81803,GSE81912_4_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CIP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30734
Nucleus of the lateral lemniscus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12792
GSE193258,GSE193259_2_v_12_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
GSE207471_2_v_3_btla_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36788
LIN28A_01_215	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.78349
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05343
hsa-miR-3691-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GSE210101,GSE210114_5_v_9_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
LMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09325
CLOCK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95777
GSE226285_3_v_1_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.1634
STAT1	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
putamen, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.58431
H3K4me1_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BT549	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.741688
hsa-miR-4766-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
Olfactory receptor neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.214
Retrochiasmatic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12947
PIP(18:2(9Z,12Z)/20:0)	HMDB Metabolites of Enzymes	1.0	null
AQP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68371
GTEX-XMD1-2826-SM-4AT5F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934726
GSE200982_0_v_2_plac8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WL46-2826-SM-3LK81	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16048
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIP(20:4(8Z,11Z,14Z,17Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
mantle zone of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53574
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
NDUFS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42387
MCF7_Triamcinolone Acetonide_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0260754
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.7643
PIP(18:1(9Z)/20:4(8Z,11Z,14Z,17Z))	HMDB Metabolites of Enzymes	1.0	null
PIP3(16:0/16:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
hela cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.367502
GINS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83189
hsa-miR-506	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
PMC12827430-41467_2025_67591_MOESM6_ESM.xlsx-Figure_4f-FOSL2_ChIP_WT-exclusive_genes_FOSL2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE174701_5_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_264_OE_GPD1_SRP252809	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.15556
PSMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41353
TKFC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45916
orbital frontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.881086
r6 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3526
Brain - Substantia nigra	GTEx Tissue Gene Expression Profiles 2023	1.0	2.22728
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.57559
PI(22:3(10Z,13Z,16Z)/18:3(6Z,9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
UBF1/2-26484160-CHIP-SEQ-FIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCIH2110	CCLE Cell Line Gene CNV Profiles	1.0	1.57387
GTEX-SNMC-0126-SM-2XCFO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95063
CAL851	CCLE Cell Line Gene Expression Profiles	1.0	2.12629
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2105
ZSCAN5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66361
YD8	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74353
SUZ12-16625203-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
r5 part of A5 noradrenergic cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03765
NCI-H1703	COSMIC Cell Line Gene CNV Profiles	1.0	2.19301
mRNA_OTX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
SEC62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14138
VZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27459
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1869	COSMIC Cell Line Gene CNV Profiles	1.0	2.19301
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PIP(20:3(5Z,8Z,11Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBJ-0008-SM-3NB26	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4969
Adrenocortical carcinoma_ACC_TCGA-OR-A5L9-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TNKS1BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67954
ADCY6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52906
GTEX-WYJK-1126-SM-3NM9Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00163
PI(20:4(5Z,8Z,11Z,14Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
MFN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07267
magnocellular diagonal band nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3423
VZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.856606
GTEX-XPVG-0826-SM-4B654	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02061
A549_Ofloxacin_10然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0253119
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21838
Lung squamous cell carcinoma_LUSC_TCGA-34-8454-11A-01R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-519c-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.017945
GTEX-NL3H-0011-R11A-SM-2I3E6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20127
Azoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.283
PCNT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04796
hsa-miR-3157-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
FARP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43595
MCF7_Capecitabine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.01869
A_CA_04_2009_7dayMOI-10^4_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.63328
PMC9130782-Table_3.xlsx-downregulated-ZNF366_ZNF366	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8329-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7617064-EMS151900-supplement-Figure_7_Source_Data.xlsx-HLC_D9_DEG-Logfold_change_threshold_1_0_1_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051797
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.829967
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6955-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34285
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.8907
A549_ENMD-2076 L-Tartaric acid_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0134619
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Metencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
lung	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.082079
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HNF4A_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
PIP3(18:2(9Z,12Z)/20:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
PIP(18:1(11Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
GTEX-PVOW-2626-SM-32PL8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26982
MCF7_Capecitabine_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0284088
A549_Decitabine_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.00873191
UMPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74739
PARD6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76956
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
DGKK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92534
VZ in caudal cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18699
ChIP_SUZ12_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
GTEX-SNOS-0003-SM-3NMAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20399
GSE197850_4_v_2_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202434,GSE202438_2_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5678-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPTSSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98175
CDK4_knockdown_225_GSE8866	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.05459
r7 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12234
UACC-893	COSMIC Cell Line Gene Mutation Profiles	1.0	null
placenta_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.13205
SUSA	DepMap CRISPR Gene Dependency	1.0	2.0221
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MED28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69324
ALG12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.80268
Brain Lower Grade Glioma_LGG_TCGA-HT-A5R5-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UPK5-0008-SM-4IHJD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860573
Prostate adenocarcinoma_PRAD_TCGA-2A-A8W1-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12013
MCF7_Triamcinolone Acetonide_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0321006
periventricular stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02649
PMC7862469-13238_2020_779_MOESM4_ESM.xlsx-FOXO3-GE_VS_WT-GeneID_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0534
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052504
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.59827
PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT38_Protein_cis-instrument_MR-Unnamed_2_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2992-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZC3H18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.69648
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RWS6-0326-SM-2XCAP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27002
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-Row_names_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of isBI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60964
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978021
HCC1359	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.839915
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PIP2(16:0/20:3(8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
Perturb_400_KO_NFE2L1_SRP333364	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.71986
SAP30	ENCODE Transcription Factor Targets	1.0	null
Pseudopalisading cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.538
Facial motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.83379
Brain Lower Grade Glioma_LGG_TCGA-P5-A736-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.28452
GSE102870_1_v_2_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SBC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2026
HINT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80528
HOXC9	ChEA Transcription Factor Targets	1.0	null
GSE184902_4_v_1_adipor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ACTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55408
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03598
GTEX-O5YV-0008-SM-4E3HP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.829357
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-938	TargetScan Predicted Conserved microRNA Targets	1.0	0.039622
Glottis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.749
ChIP_REST_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
hsa-miR-3672	TargetScan Predicted Conserved microRNA Targets	1.0	0.020071
XPO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1893
Flocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08678
PIP(20:4(5Z,8Z,11Z,14Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
skeletalmuscle	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.01461
PIP(18:1(9Z)/20:3(8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
SFN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38785
hsa-miR-1297	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
XPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30082
HUH7	DepMap CRISPR Gene Dependency	1.0	2.995
hsa-miR-4511	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
BARHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43048
placenta	HPA Tissue Gene Expression Profiles	-1.0	-0.915798
GSE142232,GSE142234_0_v_2_gcgr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A549_Trichostatin A_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0171985
PALB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3664
BCL11B_KO_GDS3178_296_mouse_striatum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
layer 3 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10827
A1207	CCLE Cell Line Gene Expression Profiles	-1.0	-3.00315
mantle zone of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19289
GTEX-U4B1-0326-SM-3DB8K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25408
m2 part of pararubral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28292
PIP2(20:3(8Z,11Z,14Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
PIP(20:4(5Z,8Z,11Z,14Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
PMC11801220-NIHMS2038999-supplement-16.xlsx-Exc-MAF-gene_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210682_0_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE165307_3_v_0_gfi1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZKSCAN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7667
GTEX-RNOR-2226-SM-2TF5O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986791
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EE-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TE-15	COSMIC Cell Line Gene CNV Profiles	1.0	2.19301
RAB39A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91678
EBLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43944
CTHRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39933
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7097-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5E-Down_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66238
cervical adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.128807
PIP3(18:0/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
hsa-miR-3156-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
GTEX-OHPL-2426-SM-48TDN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94415
PLC-like phosphodiesterase, TIM beta/alpha-barrel domain	InterPro Predicted Protein Domain Annotations	1.0	null
amygdaloid complex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00531
ZNF385A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74204
hsa-miR-129-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.017945
GTEX-U412-0008-SM-4DXTE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.899435
PMC6078963-41467_2018_5311_MOESM5_ESM.xlsx-48h_KD_UP_Vs_ATAC-z_e_o_To_AR	Rummagene Transcription Factor Associations 2026	1.0	null
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.885882
A549_BRD4770_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0164392
III	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.850685
MCF7_PJ34_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0149891
SNX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30272
phosphoric ester hydrolase activity	GO Molecular Function Annotations 2025	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
prion disease	GWASdb SNP-Disease Associations	1.0	0.739803
lingual gyrus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.866777
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01833
intermediate stratum of m2B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83477
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7235-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
integument	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MCF7_Ofloxacin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.013078
SLC9A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94512
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PCDHB12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03359
GTEX-WCDI-0008-SM-47JYE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09322
GTEX-POMQ-1426-SM-3P61D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25711
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5881-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
KDM5B_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB7A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8396
PIP(18:1(9Z)/16:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
GSS	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33323
MXI1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
temporal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05277
GTEX-XUJ4-1326-SM-4BOQ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48574
HS737T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.67403
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23555
phosphoric diester hydrolase activity	GO Molecular Function Annotations 2025	1.0	null
heart_6b	HPA Tissue Sample Gene Expression Profiles	1.0	1.43985
GTEX-PLZ4-0008-SM-48TE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31604
A549_CUDC-101_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0153374
MCF7_Prednisone_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0170124
GTEX-S4P3-1826-SM-3K2AL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938233
GSE146546,GSE146807_0_v_1_igf2bp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_13865_KO_LIN28B_SRP284310	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
PMC11214527-mmc5.xlsx-POU5F1-gene_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-1283	TargetScan Predicted Conserved microRNA Targets	1.0	0.085563
Hand1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.5782
MCF7_Resminostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0140217
A549_SRT2104_10然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0126079
MCF7_ENMD-2076 L-Tartaric acid_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0179967
NFIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63357
hsa-miR-4500	TargetScan Predicted Conserved microRNA Targets	1.0	0.241055
GTEX-PSDG-0008-SM-48TE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06455
hsa-miR-4446-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.119151
MXI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.24138
RAB43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01214
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7SF-1326-SM-4AD4P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48101
Carcass	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.066
Midbrain reticular nucleus, retrorubral area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05992
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.21905
GTEX-WVLH-0011-R11A-SM-3MJFO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69082
hsa-miR-181c	TargetScan Predicted Conserved microRNA Targets	1.0	0.009975
PMC7064337-elife-51373-supp1.xlsx-EZH2_targets_shPHF19-List_of_2084_genes_marked_by_EZH2_ChIPseq_after_PHF19_KD_shPHF19_AR	Rummagene Transcription Factor Associations 2026	1.0	null
microcellular tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26322
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26911
A549_Danusertib_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0227229
A549_UNC0379_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0164941
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.955637
caudal group of intralaminar nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03614
GTEX-S32W-0626-SM-2XCBG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49317
ChIP_MTF2_20144788	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-X4XX-2926-SM-3NMB1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02708
PIP2(18:3(9Z,12Z,15Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
Vagina	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.55472
TAF1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00298
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BV-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
putamen, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.32669
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0333
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24435
PMC8639061-pcbi.1009563.s014.xlsx-ST4-S4_Table_Phenotypic_master_regulator_MR_list_with_pleiotropy_count_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Asthma_Epithelial Cell_GSE4302	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.75172
RASIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10377
hsa-miR-3121-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.303626
TE8	CCLE Cell Line Gene Expression Profiles	-1.0	-1.73377
ChIP_H3K27me3_17603471_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
MCF7_Alisertib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0141468
MCF7_CUDC-101_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0401338
HEKTE	CCLE Cell Line Gene Expression Profiles	-1.0	-2.00041
Pituitary gland tumor cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.702
GTEX-QDT8-0011-R2A-SM-32PKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872979
hsa-miR-1208	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
RAD21	ENCODE Transcription Factor Targets	1.0	null
GTEX-OIZH-0326-SM-2HMKC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64122
GTEX-N7MS-0011-R11A-SM-2HMJS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07227
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXA2_FOXA2	Rummagene Transcription Factor Associations 2026	1.0	null
A549_Sirtinol_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0146044
PMC10020087-41388_2023_2602_MOESM3_ESM.xlsx-MCF10A_KD-GeneName_AR	Rummagene Transcription Factor Associations 2026	1.0	null
FECH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26992
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
A549_Ramelteon_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0124024
GTEX-X88G-0004-SM-47JZ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52208
PIP(18:1(11Z)/18:3(6Z,9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
PMC8881251-18_2022_4183_MOESM3_ESM.xlsx-ERM_vs_P4-DEGs_ERM_versus_P4_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM39A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34612
MCF7_Sodium Phenylbutyrate_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0153837
peripheral nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.374618
hsa-miR-4666-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.17031
GSE126345_9_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.86328
Pallidum, medial region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39846
MCF7_SRT1720 HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0172133
A549_Pelitinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0182867
hsa-miR-106b	TargetScan Predicted Conserved microRNA Targets	1.0	0.092495
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17211
hsa-miR-4434	TargetScan Predicted Conserved microRNA Targets	1.0	0.034317
A549_Pirarubicin_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0161955
ARL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76725
GTEX-XOTO-0011-R11B-SM-4B64O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09834
MCF7_Tazemetostat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0147438
PMC9843270-mmc2.xlsx-DEGs_of_three_subtypes-The_DEGs_of_TP53_type_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
FANCI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67412
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZA-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.58734
outer SZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.920148
hsa-miR-4768-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.015875
ERMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91129
Pontine reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07627
HOXB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5574
neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.047376
MCF7_Navitoclax_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0128957
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TOMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55319
acute lymphocytic leukemia	GWASdb SNP-Disease Associations	1.0	0.663947
COLO 679	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13545
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7045-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32544
hsa-miR-4427	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
CMTM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01203
mRNA_NR2F2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
A549_Cimetidine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0209019
mantle zone of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22004
Hindbrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Medial amygdalar nucleus, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20425
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41631
TECPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14346
MCF7_Toremifene Citrate_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0226397
GTEX-WCDI-0002-SM-3P61U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44372
PIP2(18:1(11Z)/16:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
NCOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68897
GTEX-XYKS-1726-SM-4E3IO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08451
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_SBP_AA-GENE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XBED-0003-SM-47JWP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
GSE205163,GSE205164_1_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-P44H-0726-SM-48TBT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00008
primary visual cortex (striate cortex, area V1/17)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.944566
intermediate stratum of isLim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10827
GSE111660_4_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
parasolitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.73205
nucleus subceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.853152
STAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54043
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WN-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_Fasudil_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0159979
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
A549_ITSA-1_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0380422
GTEX-WFG7-0826-SM-3GIKU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43743
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A_CA_04_2009_7dayMOI-10^5_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.31032
UQCRHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57763
CIB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14708
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.970535
H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Human - Motor Cortex - Cluster - FEZF2+ POGK+ Layer 6 glutamatergic neuron	HuBMAP Azimuth Cell Type Annotations	1.0	null
ANXA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41635
DDX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81994
AR-22383394-PROSTATE_CANCER-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
DCLRE1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82504
superior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02187
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_4day-MOI-10^4_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.53422
496100496_FWM_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.57112
hsa-miR-181a	TargetScan Predicted Conserved microRNA Targets	1.0	0.009975
Lung squamous cell carcinoma_LUSC_TCGA-92-7340-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-A53D-01A-32R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
ACTR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59903
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMAD2/3-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-W5X1-0001-SM-3P61V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01172
Lung squamous cell carcinoma_LUSC_TCGA-77-7142-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PLZ4-2826-SM-3P617	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911148
GTEX-T6MN-0002-SM-3NMAH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18842
MCF7_Toremifene Citrate_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0231482
MIER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35569
hsa-miR-4516	TargetScan Predicted Conserved microRNA Targets	1.0	0.03694
GTEX-O5YT-0326-SM-32PKA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71993
GTEX-S7PM-0008-SM-3NM9Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22303
pioglitazone_rattus norvegicus_gpl1355_3 months_gds4019	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-PWCY-1326-SM-48TCU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48093
PIP2(18:2(9Z,12Z)/20:3(5Z,8Z,11Z))	HMDB Metabolites of Enzymes	1.0	null
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.953112
FOXO3_01_267	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60009
MCF7_Nilotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0140243
CHRAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38716
A549_ZM 447439_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0145713
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-7351-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TNPO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34283
PIP2(20:3(8Z,11Z,14Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
VCPIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92985
GSE175787_8_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-3153	TargetScan Predicted Conserved microRNA Targets	1.0	0.03694
CDK8_knockdown_147_GSE32108	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.54706
Hypothalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.18
GTEX-W5WG-0002-SM-3NMDN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17203
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02368
CHD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68981
PMC11979751-table_s1_trajectoryderivation_elad055.xlsx-Cluster_DE_Genes_Summary-Cluster_2_AP2_Up_GTF3A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S4UY-0008-SM-3NM8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53027
A549_Tubastatin A HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0215439
PMC8482521-mmc13.xlsx-Phosphosites_48vhr_MLR-Gene_names_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3R3-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of m1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29067
GTEX-RM2N-0008-SM-48FF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
TRIP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06019
PMC11801220-NIHMS2038999-supplement-16.xlsx-Exc-SKOR2-gene_SKOR2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE225869_3_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_8832_KO_MESP1_SRP345831	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
CHD2	ENCODE Transcription Factor Targets	1.0	null
KCIMOH1	CCLE Cell Line Gene CNV Profiles	1.0	1.37991
Lung adenocarcinoma_LUAD_TCGA-44-6779-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.890088
GSE193258,GSE193259_9_v_12_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PIP2(20:0/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
EBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46144
SBC5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32317
biological regulation	GO Biological Process Annotations 2015	1.0	null
mesomere 2 (preisthmus or caudal midbrain)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55923
MCF7_Linifanib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0139081
PIP2(20:2(11Z,14Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
Perturb_7847_KD_PUM2_SRP166185	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-X5EB-0626-SM-46MVQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70408
Heart ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.135
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7680-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_Cediranib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.014139
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
TMX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61743
RAB3A_Mutation - D77G point mutation_GDS2483_698_mouse_Hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
recurrent viral infections	GWASdb SNP-Phenotype Associations	1.0	0.638696
tail of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.35118
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.111499
CZIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46551
MOV10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80999
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43318
PIP2(18:1(9Z)/16:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5894-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HES5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4969
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.10537
CCDC77	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3101
A549_Barasertib_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0169644
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of m2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23167
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0028
GTEX-P4QS-0326-SM-2I3EU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25241
NCI-H2110	COSMIC Cell Line Gene CNV Profiles	1.0	2.19301
GCDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85367
PMC9999213-mmc3.xlsx-DEGs_CSc-DEA_NB_MSC_CSc_vs_NB_CSc_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-BrtoFay_Thermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PTMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55457
LAMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.80717
Brain Lower Grade Glioma_LGG_TCGA-CS-4938-01B-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.873387
GSE242083,GSE242098_2_v_0_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48882
PI(20:2(11Z,14Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
PIP(18:2(9Z,12Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
PMC11496110-42255_2024_1140_MOESM3_ESM.xlsx-ST18_Gene_view-Supplementary_Table_18_Top_100_FAM46C_co-expressed_genes_according_to_Islet_Gene_View_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
RBBP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65949
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PI(18:1(9Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
PI(20:4(8Z,11Z,14Z,17Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
intermediate part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75797
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7372
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10214
GTEX-U3ZN-1026-SM-4DXTC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16603
A549_Dacinostat_10nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0109467
Intermediate reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17508
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.880433
isthmic part of basolateral isthmic reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.52535
Lung adenocarcinoma_LUAD_TCGA-44-7667-01A-31R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-W5X1-2326-SM-3GIL6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982215
PIP2(18:3(6Z,9Z,12Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
PMC9942993-pone.0281645.s002.xlsx-non-AR_as_all_as_gained-SYMBOL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.112322
REST	ENCODE Transcription Factor Targets	1.0	null
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35702
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BBS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84468
hsa-miR-3140-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.011888
mRNA_ASCL1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
MRPL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56026
C2CD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04168
LLC-PK1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.766
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.865058
GTEX-OOBK-0008-SM-3NB27	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51406
B4GALT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36205
PIP2(22:4(7Z,10Z,13Z,16Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
GSE224096_1_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.45871
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NHEJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5328
PIP2(20:4(8Z,11Z,14Z,17Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
MCF7_PHA-680632_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0195749
Lung squamous cell carcinoma_LUSC_TCGA-43-7657-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE219195_4_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ABC1	CCLE Cell Line Gene CNV Profiles	1.0	1.40025
intermediate part of isB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61049
PIP2(16:0/20:4(8Z,11Z,14Z,17Z))	HMDB Metabolites of Enzymes	1.0	null
SECISBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04979
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.304
GTEX-V955-0726-SM-3GAFG	GTEx Tissue Sample Gene Expression Profiles	1.0	2.42775
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.915963
AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7434-11A-01R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.64861
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055932
Variant Creutzfeldt-Jakob disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
PIP(20:1(11Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
mantle zone of p3B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00556
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4897-01A-03R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.09288
salivarygland	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.09943
GTEX-NL3H-0008-SM-4E3HU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44071
NCI-H661	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KCNC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08389
polymorph layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09489
VZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.89173
HDQ-P1	COSMIC Cell Line Gene CNV Profiles	1.0	2.19301
GSE210101,GSE210114_11_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
Androgen insensitivity syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.113
PIGO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88012
CRCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81753
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A549_Tanespimycin_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0133114
GTEX-SIU7-0001-SM-3NMAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.928747
GTEX-O5YV-0426-SM-3LK66	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949805
ovary_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.44293
PIP2(18:0/20:4(8Z,11Z,14Z,17Z))	HMDB Metabolites of Enzymes	1.0	null
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.4389
ZNF480	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4972
Superior colliculus, motor related, deep gray layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11
GTEX-WH7G-0008-SM-4LVNM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830616
GSE207471_2_v_1_btla_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-W5X1-0006-SM-3GIJZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20693
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IN-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIP(18:3(6Z,9Z,12Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NPJ7-0011-R11A-SM-2I3E8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19813
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-550a	TargetScan Predicted Conserved microRNA Targets	1.0	0.050854
KURAMOCHI	COSMIC Cell Line Gene CNV Profiles	1.0	2.19301
PIP2(18:1(11Z)/18:3(9Z,12Z,15Z))	HMDB Metabolites of Enzymes	1.0	null
TMEM175	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79125
PIP(16:0/20:3(8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
MCF7_AZ 960_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0222062
PI(22:5(7Z,10Z,13Z,16Z,19Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
MCF12A	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.11477
NCI-H196	COSMIC Cell Line Gene CNV Profiles	1.0	2.19301
NDFIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8045
GTEx AdiposeTissue 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	15.1824
H3K27me3_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-US-ID_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4693-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
lateral part of MM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61327
PGR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65799
RIOK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80389
GTEX-OXRL-0326-SM-2I3F2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08062
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25336
CHK2_KD_GSE54268_667_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC7064337-elife-51373-supp1.xlsx-MTF2_targets_shCTR-List_of_2011_genes_marked_by_MTF2_ChIPseq_in_control_conditions_shCTR_MTF2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
mantle zone of isLim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14449
WDR26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31246
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.05447
Diencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.18
MCF7_BMS-754807_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0138723
PIP2(18:2(9Z,12Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
TNK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17189
Plagl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.1658
dorsolateral (non-cerebellar) part of isA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01382
PIP(18:2(9Z,12Z)/20:3(5Z,8Z,11Z))	HMDB Metabolites of Enzymes	1.0	null
GSE180185_4_v_10_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HES2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.766
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
A549_Quisinostat_10nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.00924308
A549_Sirtinol_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0168731
GSE223241_2_v_0_cdkn2a_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PI(20:4(5Z,8Z,11Z,14Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
GSE248935_1_v_0_cd14_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-62-8399-01A-21R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PIP2(18:1(9Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
mRNA_CBX8_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
RASL11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06532
ovary	GTEx Tissue Gene Expression Profiles	1.0	1.41207
hsa-miR-4420	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-SYMBOL_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T6MN-0011-R11A-SM-32QOX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72923
TBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.747
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.20169
GTEX-SN8G-0008-SM-4DM4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36193
GSE196259_1_v_3_gcm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-548ab	TargetScan Predicted Conserved microRNA Targets	1.0	0.219115
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
CCND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56081
PMC7594423-12915_2020_895_MOESM13_ESM.xlsx-Table_S6B-Table_S6B_-_Differentially_Expressed_genes_shared_between_BRCA_TRIM25_amp_and_Type_II_LGG_CIC_Del_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
PI(18:2(9Z,12Z)/20:3(5Z,8Z,11Z))	HMDB Metabolites of Enzymes	1.0	null
PI(20:3(8Z,11Z,14Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.59564
LIMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66711
C7orf25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61877
PIP2(22:5(4Z,7Z,10Z,13Z,16Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
PITX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37754
RNF168	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50944
GSE216273,GSE216292_0_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
acute lymphatic leukemia	GWASdb SNP-Phenotype Associations	1.0	0.56762
A549_GSK1070916_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.016301
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K9me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PIP2(18:0/20:3(5Z,8Z,11Z))	HMDB Metabolites of Enzymes	1.0	null
A549_Belinostat_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.026873
KMT2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96041
GTEX-O5YW-0326-SM-2I5EI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904116
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052844
ELF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37233
TE-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.19301
Cerebellum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-S341-2026-SM-2XCAA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92246
GTEX-VJYA-0001-SM-3NMDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18418
H3K4me1_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MCF7_UNC0631_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.018275
PMC7062471-elife-52504-supp6.xlsx-TEAD4_motif_in_OCR_around_DEGs-Gene_ID_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-UTHO-0011-R11A-SM-3GIJE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.2248
LRRC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32714
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-2909	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
PMC12619835-41467_2025_66007_MOESM13_ESM.xlsx-Sheet1-Basal_like_KLF5_peaks_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-1253	TargetScan Predicted Conserved microRNA Targets	1.0	0.119151
SUZ12-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
PI(22:5(7Z,10Z,13Z,16Z,19Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4865-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pronephric tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.6
GTEX-X585-0011-R11B-SM-46MUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34085
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3358-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8561673-NIHMS1742950-supplement-Table_S7.xlsx-Housekeeping_MYC_ProxTubGenes-Proximal_Tubule_Enriched_Genes_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
bronchoalveolar system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.233731
TIMMDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73534
Brain Lower Grade Glioma_LGG_TCGA-HT-7607-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25211
Brain Lower Grade Glioma_LGG_TCGA-HT-7611-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.845937
HT-1376	COSMIC Cell Line Gene CNV Profiles	1.0	2.19301
METTL22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5624
ATM_KD_GSE54268_662_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
STRBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.08574
HCE-4	COSMIC Cell Line Gene CNV Profiles	1.0	2.19301
GTEX-TKQ1-0008-SM-4DXSO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08638
PMC7591516-41467_2020_18955_MOESM6_ESM.xlsx-Overlap_DEGs_MSC_Diff_GCTB-Gene_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Medial amygdalar nucleus, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06861
hsa-miR-3158-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23311
NUDT13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73439
GTEX-X3Y1-0226-SM-3P5Z5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48508
RNF125	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14727
r5 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60534
CAVIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95139
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09231
hsa-miR-23b	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
GTEX-RUSQ-0526-SM-2TF72	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967092
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bonemarrow	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.22119
TCF4	ChEA Transcription Factor Targets	1.0	null
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16022
SW1573	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-P44H-0011-R11A-SM-2XCER	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74341
GSE203308_1_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SH3BP5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08912
PIP(20:4(8Z,11Z,14Z,17Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
GTEX-QDT8-3026-SM-32PKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10696
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CPLANE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21402
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04198
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-gene_id_y_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_3686_KD_RARRES2_SRP287866	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.91489
HOXC9-25013753-NEUROBLASTOMA BE2-C-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-374c	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
Perturb_2816_KD_SUFU_SRP346101	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.28304
r2 part of nucleus subcoeruleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03807
PIP(20:1(11Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PIP2(20:1(11Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
PI(18:1(11Z)/20:4(8Z,11Z,14Z,17Z))	HMDB Metabolites of Enzymes	1.0	null
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_CUDC-101_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0146367
NCIH1869	CCLE Cell Line Gene CNV Profiles	1.0	2.22096
H3K27me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
A549_ZM 447439_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0141639
GSE112761,GSE112767_2_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.25951
GTEX-O5YV-0326-SM-2I5H2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00906
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5680-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PI(18:0/16:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
GSE210101,GSE210114_7_v_9_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5303304-13073_2017_407_MOESM3_ESM.xlsx-mycn-sy5y-se_single_24DMSO_vs_2-Table_S2_Genes_differentially_expressed_by_24h_RA_treatment_DE_comparison_with_SY5Y-MYCN_control_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
REST_01_136	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.76431
CPSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56669
layer I of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.867691
GSE154081_3_v_0_sildenafil_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64656
HTT	ChEA Transcription Factor Targets	1.0	null
MCF7_BMS-911543_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0136263
GSE227592_10_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21692
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	3.37198
ovary	HPA Tissue Gene Expression Profiles	1.0	1.31526
GSE129241_4_v_6_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BNIP3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42733
hsa-miR-548k	TargetScan Predicted Conserved microRNA Targets	1.0	0.212286
PIP2(16:1(9Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2697-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8432-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1208	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
LRR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2517
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.873249
hsa-miR-23a	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
SW1271	COSMIC Cell Line Gene Mutation Profiles	1.0	null
shsy5y	HPA Cell Line Gene Expression Profiles	1.0	0.825613
locus ceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.37255
GTEX-PLZ6-0008-SM-48TD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0403
GTEx Vagina 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	3.5189
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
preopto-hypothalamic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17508
hsa-miR-26a	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
liminal part of alar isthmus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14362
GTEX-X62O-0008-SM-46MU5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0073
INAFM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7735
Lung adenocarcinoma_LUAD_TCGA-55-8094-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PI(22:3(10Z,13Z,16Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12616242-can-24-3452_supplementary_table_s6_suppst6.xlsx-EWSR1FLI1-KDM6A-targets_down-EWSR1_FLI1-KDM6A_downregulated_targets_upon_KDM6A_knockout_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
COLO829	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55713
PFDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29278
GSE126345_7_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
GTEX-XQ8I-0226-SM-4BOPM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13074
ALDOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56273
PIP(20:3(5Z,8Z,11Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
Nr1h2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.5387
GTEX-WL46-0011-R11A-SM-3MJFT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48761
PI(18:1(9Z)/20:4(5Z,8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
PMC6078963-41467_2018_5311_MOESM5_ESM.xlsx-48h_KD_UP_Vs_ATAC-mgi_database_human_gene_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PIP2(16:1(9Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
USP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51671
RNF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16394
hsa-miR-4695-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
H3K27me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-616	TargetScan Predicted Conserved microRNA Targets	1.0	0.039622
GTEX-WHPG-1026-SM-3NMBA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892581
NCBP2AS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5464
brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.201635
A549_Barasertib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0178962
SRSF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.214
NBPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9475
VSIG10L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35089
periventricular stratum of m2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36177
GTEX-PWCY-0526-SM-2I3ER	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3483
PIP3(18:1(11Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R7-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
PIP2(16:0/22:5(4Z,7Z,10Z,13Z,16Z))	HMDB Metabolites of Enzymes	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JT-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFNA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37104
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PIP2(18:1(9Z)/20:3(5Z,8Z,11Z))	HMDB Metabolites of Enzymes	1.0	null
ATF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94542
PMC7617064-EMS151900-supplement-Extended_Data_Figure_5_Source_Data.xlsx-CLC_D9_DEG-Logfold_change_threshold_1_0_1_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_Barasertib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0212424
TFAP2C	ChEA Transcription Factor Targets	1.0	null
superficial stratum of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02588
CROCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44445
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RP-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17947
PI(18:0/16:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
GTEX-P78B-1926-SM-3P616	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43209
H3K27me3_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7731-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4262	TargetScan Predicted Conserved microRNA Targets	1.0	0.003282
ACP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74467
MFM-223	COSMIC Cell Line Gene CNV Profiles	1.0	2.19301
UGT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07234
GATA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9274
PI(18:1(11Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mantle zone of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36388
NCI-H2009	COSMIC Cell Line Gene CNV Profiles	1.0	2.19301
PIP2(16:0/16:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
hsa-miR-589	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
MCF7_AZ 960_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0260285
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.873416
Human - Kidney - L1 - Fibroblast	HuBMAP Azimuth Cell Type Annotations	1.0	null
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.836214
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC7591516-41467_2020_18955_MOESM6_ESM.xlsx-Overlap_DEGs_MSC_Diff_GCTB-Symbol_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_Mercaptopurine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0516314
FOXA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09596
SOX17_OE_GDS3300_124_human_HESC (CA1 and CA2)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PI(22:3(10Z,13Z,16Z)/16:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
UTY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03709
SLC30A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29253
Olfactory tubercle, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12947
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.953103
head of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01672
VDAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90865
GSE205163,GSE205164_9_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
KDF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74845
RPP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45765
TCF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34428
XPO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0842
IPC298	CCLE Cell Line Gene Expression Profiles	-1.0	-2.53269
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.54312
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.93443
hsa-miR-34b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
PIP2(20:1(11Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.889289
posteroventral (inferior) parietal cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.911248
hsa-let-7d	TargetScan Predicted Conserved microRNA Targets	1.0	0.265648
PMC6137307-mmc2.xlsx-STAT2-IFNa-Table_S1_STAT2-IFNa_Related_to_Figures_1_4_STAT2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9613
H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SRF	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE77178_5_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10214
STRADA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02117
duodenum	HPA Tissue Protein Expression Profiles	1.0	1.51891
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H250	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TAL1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
ZNF32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63099
GTEX-XGQ4-0008-SM-4AT3Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10177
HEY1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1781
DCAF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51062
KIF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91674
ARL6IP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53387
PMC8881251-18_2022_4183_MOESM2_ESM.xlsx-ERM_vs_P1-DEGs_ERM_versus_P1_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
PIP2(18:3(9Z,12Z,15Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.02141
A549_Motesanib Diphosphate_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0171069
HDAC2	ENCODE Transcription Factor Targets	1.0	null
17297478-SuppTable5	GeneSigDB Published Gene Signatures	1.0	null
TE10	CCLE Cell Line Gene CNV Profiles	1.0	1.34886
PIP2(20:4(8Z,11Z,14Z,17Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
MCF7_AZ 960_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0125363
GSE210101,GSE210114_0_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05445
laterodorsal part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12921
stomach	HPA Tissue Protein Expression Profiles	1.0	1.00026
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16827
H3K9me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC5303304-13073_2017_407_MOESM4_ESM.xlsx-mycn-sy5y-se_single_24DMSO_vs_2-Table_S3_Genes_differentially_expressed_by_24h_RA_and_48h_Dox_co-treatment_DE_comparison_with_SY5Y-MYCN_control_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
globus pallidus, external segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.89711
KNS-81-FD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PIP(20:3(8Z,11Z,14Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
liminal part of the r6 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27126
hsa-miR-508-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.5447
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PIP(18:1(11Z)/20:3(5Z,8Z,11Z))	HMDB Metabolites of Enzymes	1.0	null
PMC8709578-elife-69843-supp4.xlsx-HSF1_ChIP-seq_peaks-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
OACP4C	COSMIC Cell Line Gene CNV Profiles	1.0	2.19301
GOLGA6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38285
HCC70	COSMIC Cell Line Gene CNV Profiles	1.0	2.19301
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03789
GSE144838_2_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE140646_0_v_1_atf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.17795
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.937408
hsa-miR-485-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.034317
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.43635
GSE205163,GSE205164_5_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.16243
GTEX-T2IS-2026-SM-4DM6W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15131
PMC12549544-mmc2.xlsx-AA_D1_VS_D7-Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
A549_Curcumin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0146502
SOWAHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42698
PPDPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03801
hsa-miR-3147	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GSE221327_5_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-L9-A443-01A-12R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PI(18:1(9Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
respiratory mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.592444
GTEX-UPIC-0002-SM-3NMDC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44982
outer SZ in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.945575
Adrenocortical carcinoma_ACC_TCGA-OR-A5JZ-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_INO-1001_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0233462
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33588
Bulbourethral gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.659
PLEKHO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64746
hsa-miR-218	TargetScan Predicted Conserved microRNA Targets	1.0	0.062888
hsa-miR-3119	TargetScan Predicted Conserved microRNA Targets	1.0	0.092495
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01627
hsa-miR-520c-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.075559
HINFP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8482
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2638
PI(20:3(5Z,8Z,11Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
MCF7_Entacapone_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0158206
GTEX-T5JC-0011-R11A-SM-32PMB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20368
GATA3	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3920	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
PIP(18:1(9Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
H3K4me1_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE195559_8_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRL-0008-SM-3NB29	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24506
GSE210101,GSE210114_8_v_9_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-Q2AH-0008-SM-48U2J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31877
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.928437
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COLO-800	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SUM1315MO2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.23611
A549_Filgotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0141305
LANCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26343
PI(20:2(11Z,14Z)/20:2(11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.6225
RAB2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38721
MCF7_Avagacestat_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0133014
BRD3OS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54918
hsa-miR-4531	TargetScan Predicted Conserved microRNA Targets	1.0	0.062888
GSE195503_1_v_2_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EYA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9417
PIP(16:1(9Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC11615365-41467_2024_54246_MOESM5_ESM.xlsx-RT112-Numb-KD_vs_Ctr-KD-ensemblGeneId_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GOLM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.59659
PPP3R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11573
Common cardinal vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.511
Sertoli cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.889
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47373
VZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.991161
GSE221327_4_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
bcl11b_18199763_brain_lof_mouse_gpl1261_gds3178	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.055202
posteroventral (inferior) parietal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0957
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A42L-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-33-4533-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_Danusertib_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0173359
BGC823	CCLE Cell Line Gene CNV Profiles	1.0	1.8349
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.978173
PIP(18:3(6Z,9Z,12Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE129241_3_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r1 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25668
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.66396
hsa-miR-519d	TargetScan Predicted Conserved microRNA Targets	1.0	0.056784
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6090-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
septopallidal transition area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66303
GTEX-XYKS-0226-SM-4BRW3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922039
MORN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.581
GTEX-UJHI-0426-SM-3DB8Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72878
adrenal_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.0321
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-A4AQ-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PI(16:1(9Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
hsa-miR-1200	TargetScan Predicted Conserved microRNA Targets	1.0	0.088999
PIP(18:0/20:4(5Z,8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
GSE256181_1_v_3_etv2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Atrophy	CTD Gene-Disease Associations	1.0	1.32726
PIP2(20:3(5Z,8Z,11Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
GSE210101,GSE210114_6_v_9_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
VZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.62578
GSE180185_7_v_10_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MKN-45 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.997
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19454
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CASD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29688
AHSA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51826
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81J-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LEDGF_KD_GDS1580_249_human_293T cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
hsa-miR-4709-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
intermediate stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15155
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.965633
MCF7_Momelotinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0204263
Lassa Fever Virus_4hr_24069471_GSE41300	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.67909
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A12J-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-370	TargetScan Predicted Conserved microRNA Targets	1.0	0.212286
SLC20A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15825
ZNF449	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7607
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Unnamed_12_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
METTL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52042
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A4AB-01B-12R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer 3 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16877
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-CA-04-2009(H1N1)_7Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.4591
ovary_6b	HPA Tissue Sample Gene Expression Profiles	1.0	0.902291
CORL279	CCLE Cell Line Gene CNV Profiles	1.0	1.95164
hsa-miR-329	TargetScan Predicted Conserved microRNA Targets	1.0	0.020071
RUNDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61041
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052963
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
GSE217685_0_v_1_ddx20_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.896671
MCF7_Sorafenib Tosylate_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0193824
TRAPPC2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12221
SNU-601	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.915717
GTEX-XQ3S-0626-SM-4BOOB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01901
GSE172494_3_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07897
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16022
A549_TMP195_1然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0143842
GSE205163,GSE205164_3_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XLM4-0008-SM-4AT4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32279
MZ in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.927557
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE234514,GSE234516_2_v_0_mitf_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S341-0008-SM-4AD6D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38626
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMRM-0526-SM-2I5GA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53182
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18709
PIP2(22:3(10Z,13Z,16Z)/16:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
GTEX-UPK5-0003-SM-3NMDI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13889
Swine testicular cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.015
GTEX-OHPN-0008-SM-4E3HW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.834848
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_WP1066_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0159228
PR8(H1N1)_12hour_None_GSE37245	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.78797
Pituitary gland cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.695
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PIP2(18:1(11Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
hsa-miR-302d	TargetScan Predicted Conserved microRNA Targets	1.0	0.069137
hsa-miR-4433	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GTEX-VUSG-0003-SM-3NMDK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847855
ATAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38017
RUNX1_KO_GDS1511_251_mouse_Embryos at E12	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BF-11A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE227592_0_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8016886-41419_2021_3630_MOESM6_ESM.xlsx-Sheet1-Table_S5_Differentially_expressed_genes_identified_between_HOXC6-low_and_HOXC6-high_expression_CRCs_using_TCGA_cohort_HOXC6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVUS-2926-SM-3GIJB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26614
GSE233049_1_v_3_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
PIP3(18:1(9Z)/20:3(5Z,8Z,11Z))	HMDB Metabolites of Enzymes	1.0	null
GSE175787_4_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193258,GSE193259_5_v_12_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
WDR55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04046
H3K4me1_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PHF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63966
PIP2(18:1(11Z)/20:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
A549_Maraviroc_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0219776
pallidal islands of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09842
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.72863
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2805
EPB41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53089
GTEX-U3ZN-0002-SM-3NMDF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
Rectum adenocarcinoma_READ_TCGA-AF-2690-01A-02R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_BE2C_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWOO-0526-SM-2S1Q3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63557
DCAF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.3253
EW8	CCLE Cell Line Gene Expression Profiles	-1.0	-1.83922
PIP2(20:3(8Z,11Z,14Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
GSE111660_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE232836_2_v_6_morphine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
placenta_3a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.10585
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.75313
GSE156454_0_v_1_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
XE-69-AT35_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.77861
SLR23	CCLE Cell Line Gene Expression Profiles	-1.0	-1.65429
GSE153836_11_v_2_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ECC12	CCLE Cell Line Gene Expression Profiles	1.0	1.70944
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.890067
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841263
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
shell of SCH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29526
HMCB	CCLE Cell Line Gene Expression Profiles	-1.0	-1.90863
A549_MLN8054_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0151294
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6938-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE101336_1_v_2_decitabine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
AARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50495
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PIP2(16:0/22:4(7Z,10Z,13Z,16Z))	HMDB Metabolites of Enzymes	1.0	null
GSE164529_0_v_3_tamoxifen_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ADPGK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16777
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81D-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COPS7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49322
CLPTM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39108
PIP(18:1(9Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Periventricular zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59757
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-GENE_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.889289
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05369
hsa-miR-3120-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
CSPG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21138
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
A549_Divalproex Sodium_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0146488
OCILY19	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45185
A549_JNJ-7706621_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0135573
mRNA_T_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
mRNA_SOX2_17515932	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
PIP(20:3(5Z,8Z,11Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21914
SARS-CoV MA15_Day7-C57BL6_None_GSE50878	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.25526
GTEX-R53T-0926-SM-3GADH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72945
496100559_FWM_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.29463
HEP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48993
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATP11C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18733
KIF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27982
ESET-19884257-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TEAD4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AR-22383394-PROSTATE-CANCER-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Nearest_Ensembl_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
PCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7836
SETD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97153
NPIPA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75638
preisthmic tegmentum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65531
periventricular stratum of IC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16613
Pallidum, dorsal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09131
ZNF730	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14027
PI(18:1(9Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
cuneiform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81645
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5591-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PDE12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9207
Kidney - Cortex	GTEx Tissue Gene Expression Profiles 2023	1.0	2.67458
GSE205163,GSE205164_9_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLDIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10398
H3K4me2_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC12478272-mmc1.xlsx-Table_S7-Supplementary_Table_7_Proteome-wide_MR_and_sensitivity_analysis_results_using_the_brain_pQTL_dataset_from_Wingo_et_al_1_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
ST14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59268
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-R55E-2526-SM-2TC6H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834865
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.824536
CIART	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64167
GTEX-V1D1-0626-SM-4JBHN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833556
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6796-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE101239_5_v_0_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PDPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77849
GSE140200_1_v_0_trim59_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PDS5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78285
MXI1	ENCODE Transcription Factor Targets	1.0	null
GTEX-QMR6-0008-SM-447AV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00559
ZNF578	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88834
GTEX-X4EP-0326-SM-3P5Z6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930796
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.07439
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18209
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
RPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28041
GTEX-P4QS-0008-SM-48TDY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.964297
PIP2(16:1(9Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
GSE210682_2_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
USP49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24793
SNU899	CCLE Cell Line Gene CNV Profiles	-1.0	-2.06025
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
blood	GTEx Tissue Gene Expression Profiles	-1.0	-2.07771
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1828
PIP2(18:2(9Z,12Z)/20:2(11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
E2F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55058
layer III of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27839
GTEX-XBEC-1226-SM-4AT65	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05629
hsa-miR-4465	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
heart	GTEx Tissue Gene Expression Profiles	1.0	1.3817
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48993
Duodenum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.941293
preopto-hypothalamic band	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53574
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.985267
hsa-miR-455-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.039622
heart_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.1631
Ezh2_deficiency_GDS2717_141_mouse_lymph node T cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE102132_2_v_1_irf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MLLT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91003
Ovarian Neoplasms	CTD Gene-Disease Associations	1.0	1.01549
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
PI(18:2(9Z,12Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
ZNF680	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46246
PIP(20:4(5Z,8Z,11Z,14Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
hsa-miR-4267	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
Primary somatosensory area, trunk, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03497
ZSCAN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79286
GSE209598_0_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Spz1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.1667
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-Fay_Heat_LPStoThermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
SYT12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.95235
NXPE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30472
PMC11932929-41388_2024_3264_MOESM4_ESM.xlsx-p_0_05_FC_0_5_n_675-Differentially_expressed_genes_in_MCF7_AR-isolated_BCSCs_after_4_days_GSK591_500nM_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_7892_KD_LAS1L_SRP321656	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
voltage-gated potassium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.939
GSE205730,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-4329	TargetScan Predicted Conserved microRNA Targets	1.0	0.115091
OVISE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32979
GSE175787_13_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
BCL11B_KO_GSE9330_4_mouse_brain (striatum)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE238018_3_v_0_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PI(20:3(8Z,11Z,14Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
hsa-miR-30b	TargetScan Predicted Conserved microRNA Targets	1.0	0.226173
EPAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51012
CHRNA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08401
PIP2(20:1(11Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
PIP(20:4(5Z,8Z,11Z,14Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
GTEX-WQUQ-1326-SM-3MJFF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55534
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3658	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
GTEX-WZTO-0011-R11A-SM-4E3K9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02335
GSE48812_0_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5L5-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DNAJC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51474
leukemia	GWASdb SNP-Disease Associations	1.0	0.369791
MCF7_Ofloxacin_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0173588
hsa-miR-1290	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
GTEX-RTLS-0008-SM-48FET	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03308
GSE237040_0_v_5_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5402-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_14661_KO_Insm1|Pax6_ERP127840	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
MCF7_UNC0631_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0225531
PIP(16:1(9Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-Row_names_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
A549_UNC1999_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0121497
TMCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09184
PI(16:0/22:4(7Z,10Z,13Z,16Z))	HMDB Metabolites of Enzymes	1.0	null
GTEX-WFG7-0726-SM-3GIKO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23984
hsa-miR-548d-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.029271
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.90054
TNFRSF11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87197
mRNA_EOMES_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NS-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIP2(20:3(5Z,8Z,11Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
hsa-miR-548y	TargetScan Predicted Conserved microRNA Targets	1.0	0.212286
GSE210101,GSE210114_5_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
OTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32801
PIP(20:4(8Z,11Z,14Z,17Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
ABC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58613
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18866
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A23B-11A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB	JASPAR Predicted Transcription Factor Targets	1.0	null
RBL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47228
SFRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34031
hsa-miR-372	TargetScan Predicted Conserved microRNA Targets	1.0	0.072324
H3K27me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-2666-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PITRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76867
HSPA14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92467
OTX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53974
MRPS30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38384
MORCPR	CCLE Cell Line Gene CNV Profiles	1.0	1.38065
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17508
GSE210101,GSE210114_2_v_9_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4536
nasal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.626677
GSE227592_9_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.07686
parabigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04156
CAL851	CCLE Cell Line Gene CNV Profiles	1.0	1.45043
substance dependence	GWASdb SNP-Disease Associations	1.0	0.290422
CAAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4462
GSE48812_0_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
embryonic stem feeder layer	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.68594
Acute Myeloid Leukemia_LAML_TCGA-AB-2857-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACVR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26537
PIP2(18:2(9Z,12Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
PI(22:3(10Z,13Z,16Z)/18:3(9Z,12Z,15Z))	HMDB Metabolites of Enzymes	1.0	null
PMC11385078-jciinsight-9-172336-s272.xlsx-1DEseq2_Report_AA_BL_vs_EA_BL-Unnamed_1_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.59635
MCF7_SL-327_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0120811
PIP(18:2(9Z,12Z)/20:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
GTEX-UTHO-2926-SM-3P5Z9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23365
PMC4053969-gb-2013-14-7-r81-S3.XLSX-YB1-targeted-genes-gene_YBX1	Rummagene Transcription Factor Associations 2026	1.0	null
DZIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.96722
DCANP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11617
brain disease	GWASdb SNP-Disease Associations	1.0	0.311359
POLE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8369
PIP2(18:0/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
ventral posterolateral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03765
Perturb_13930_OE_DLG2_ERP119345	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	19.699
lateral IC periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40456
intermediate stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.43468
Olfactory tubercle	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1019
COQ9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43007
EVPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15378
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903287
H3K27me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cerebellar cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.02952
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.089166
Perturb_14659_KO_Insm1_ERP127840	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-18.1487
hsa-miR-302c	TargetScan Predicted Conserved microRNA Targets	1.0	0.069137
SLC25A17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12559
hsa-miR-548b-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.205675
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.918353
HSPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35102
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TNFRSF12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19199
PI(18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z))	HMDB Metabolites of Enzymes	1.0	null
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.917472
m1Lim part of the midbrain reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29187
GTEX-VUSG-0726-SM-3GIK1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91242
pallidal part of olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06545
PIP(16:1(9Z)/16:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
VAMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82427
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.51329
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-30a	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
GSE214505_0_v_1_akr1b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_SRT2104_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0179829
ZNF79	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96694
intermediate stratum of DTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06545
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3C7-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
basolateral nucleus (basal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.976396
PDF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2103
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PI(20:4(8Z,11Z,14Z,17Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
PIP2(18:3(9Z,12Z,15Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.20656
H3K4me1_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PIP2(18:3(6Z,9Z,12Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
Vasculature-fibroblast	Tabula Sapiens Gene-Cell Associations	1.0	10.236
isthmic part of mesencephalic trigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0677
GSE224294_3_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	1.0	null
raphe nuclei of medulla	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.930337
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.88405
intermediate stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.02367
PI(18:1(9Z)/20:4(8Z,11Z,14Z,17Z))	HMDB Metabolites of Enzymes	1.0	null
ZNF449	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87376
PPM1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22435
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5877-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G-361	COSMIC Cell Line Gene Mutation Profiles	1.0	null
small intestine	HPA Tissue Protein Expression Profiles	1.0	1.51891
APP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63123
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.968373
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.9894
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11849
hsa-miR-548f	TargetScan Predicted Conserved microRNA Targets	1.0	0.029271
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.95349
OGFOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53959
JHU-029	COSMIC Cell Line Gene CNV Profiles	1.0	2.19301
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056238
GTEX-WHSE-2926-SM-3NMBG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930061
PIP3(18:1(9Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
PMC2866657-pone.0010547.s001.xls-ERG-high-GENES_DOWNREGULATED_IN_ERGhigh_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T6MO-0008-SM-4DM6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.94703
peduncular nucleus of the stria medullaris	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18725
hsa-miR-33a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE150669_0_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE174701_1_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
PI(16:0/20:0)	HMDB Metabolites of Enzymes	1.0	null
hsa-miR-3941	TargetScan Predicted Conserved microRNA Targets	1.0	0.047969
cdx2_20696899_caco2_lof_human_gpl570_gse22572	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	1.57577
GATA3-24758297-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC6080909-JEM_20171312_TableS1.xlsx-miR-196_predicted-Table_S1_miR-196a_b_predicted_targets_by_PITA_PicTar_TargetScan_and_DIANA_prediction_algorithms_ZFP1	Rummagene Transcription Factor Associations 2026	1.0	null
ADGRA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98945
NCI-H1395	COSMIC Cell Line Gene CNV Profiles	1.0	2.19301
ALKBH7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34428
hsa-let-7c	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
Breast Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
ZC3H7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4411
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.45784
S117	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61514
body of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12855
MCF7_Navitoclax_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0281573
superficial stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08789
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.905887
Mouse - Motor Cortex - Cross-Species Cluster - Layer 6 glutamatergic neuron, intratelencephalon-projecting_1	HuBMAP Azimuth Cell Type Annotations	1.0	null
primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.98639
PI(18:1(11Z)/20:3(5Z,8Z,11Z))	HMDB Metabolites of Enzymes	1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_SBP_AA-SYMBOL_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
tobacco use disorder	GAD Gene-Disease Associations	1.0	null
Sarcoma_SARC_TCGA-DX-A2IZ-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIP2(16:2(9Z,12Z)/22:3(10Z,13Z,16Z))	HMDB Metabolites of Enzymes	1.0	null
GTEX-Q2AG-0011-R11A-SM-2HMKZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49561
PI(16:1(9Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
GSE195743_3_v_2_lhx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mRNA_DLX3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CCDC97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19469
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-WK-A8XO-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RAB29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51244
SYPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88749
PDSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46238
ZNF132	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.99372
GTEX-TML8-0001-SM-3NMAF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934328
Lung squamous cell carcinoma_LUSC_TCGA-56-8626-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PIP(18:0/18:3(9Z,12Z,15Z))	HMDB Metabolites of Enzymes	1.0	null
CL11	CCLE Cell Line Gene Expression Profiles	-1.0	-2.20728
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE174701_5_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GPR107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25223
A549_Carmofur_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0134467
PMC12209767-bcd-25-0099_supplementary_table_s2_suppst2.xlsx-C_DEGs_RNA-seq-Supplementary_table_S2C_List_of_differentially_expressed_genes_in_IGHUND_vs_IGH_GCB_MB2_DE_DLBCL_HGBCL-DH-BCL2_-BCL6_BCL6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SOX2-22085726-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
isthmic part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.98652
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A655-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9533694-MOL2-16-3410-s013.xlsx-FIR20vsREST_DEMs-FIR20_vs_REST_DEMs_Up_REST	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Clevudine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0146277
GSE210101,GSE210114_8_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pedunculopontine nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.61878
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
IST-MEL1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853281
PIP(18:0/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
Perturb_8968_KD_pCDNA3.1_SRP068139	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
intermediate part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16712
dorsal part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17508
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_30min-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PIP(18:2(9Z,12Z)/20:2(11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
JKAMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35113
respiratory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.294581
MRPS27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06858
PMC3906982-1471-2164-14-830-S1.xlsx-Sheet1-Table_S1_HOXC9-responsive_genes_HOXC9	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_SB431542_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0105048
PI(22:4(10Z,13Z,16Z,19Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
posterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06296
PIP2(20:3(8Z,11Z,14Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
PMC11801220-NIHMS2038999-supplement-14.xlsx-Exc-MAF-gene_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RNF20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63713
submammillothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27612
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65299
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.18331
NRL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6453
H3K27me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3ZF-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TFAP2C-20629094-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE192513,GSE192515_1_v_0_atg16l1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_13869_KO_LIN28B_SRP284310	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.9198
PI(18:0/20:3(8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
FBXL19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83599
Anterior olfactory nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12152
claustrum, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.944642
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
LMNTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09079
r6 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78971
APBB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27284
DLX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7856
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.996667
SETDB1	ChEA Transcription Factor Targets	1.0	null
GTEX-R55G-0008-SM-48FEX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33544
PIP2(16:0/20:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
GSE254649_3_v_0_cstf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056904
ZNF157	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10501
GTEX-OHPL-0326-SM-33HC8	GTEx Tissue Sample Gene Expression Profiles	1.0	2.21825
hsa-miR-4775	TargetScan Predicted Conserved microRNA Targets	1.0	0.248923
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_1day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.79352
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.862145
HCC70	CCLE Cell Line Gene Expression Profiles	1.0	2.65496
PI(18:3(9Z,12Z,15Z)/22:3(10Z,13Z,16Z))	HMDB Metabolites of Enzymes	1.0	null
MYOG	ENCODE Transcription Factor Targets	1.0	null
ChIP_SETDB1_19884257	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21976
ACTN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86423
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.80991
lateral part of the isB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52996
GTEX-R55G-0526-SM-2TC5O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2343
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QLQ7-0008-SM-447AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
Pancreatic adenocarcinoma_PAAD_TCGA-H6-8124-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCILY3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48066
amygdalostriatal transition area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.82405
carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05366
GSE133691_2_v_0_lgr5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormality of the immune system	GWASdb SNP-Phenotype Associations	1.0	0.101537
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PIP2(18:1(9Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
VZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.89334
mRNA_MEF2C_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-Q734-0726-SM-48TZP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26919
hsa-miR-1284	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
HNF4G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41047
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-upregulated_in_ATF4OE_txt-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-3659	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
LPXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17158
AVPI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80393
H3K4me1_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC6934839-41598_2019_56277_MOESM2_ESM.xlsx-ONECUT2_DOWN-Gene_Symbol_ONECUT2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9170821-JCMM-26-3183-s001.xlsx-Astro_DAPI_ERG_VaD_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P4PQ-0326-SM-2HMJ8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59791
GTEX-T2IS-2926-SM-32QPO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18378
layer 1 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75277
PELI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99235
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01968
hsa-miR-4452	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Prostate adenocarcinoma_PRAD_TCGA-EJ-8469-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AR-21915096-LNCAP-1F5-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
POU5F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52164
GTEX-OIZH-3026-SM-3NB1G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909744
GSE210101,GSE210114_6_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YT-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TM-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.899
NDUFB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09476
HES6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33827
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31653
GTEX-R55F-0011-R8A-SM-2TF4F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869529
A549_Tazemetostat_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0305219
HNRNPUL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00588
GTEX-R45C-0008-SM-48FF2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31836
RANBP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46741
FNBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55131
GSE175787_13_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA2	ENCODE Transcription Factor Targets	1.0	null
behavioral abnormality	GWASdb SNP-Phenotype Associations	1.0	1.0799
variant creutzfeldt-jakob disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.30794
Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7GZ-11A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXA1_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16606
A549_Hesperadin_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0145917
PSME3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49898
hsa-miR-4735-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
A549_FLLL32_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0202047
FEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47126
hsa-miR-4430	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
locus ceruleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.0265
SETBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.15779
ARHGAP17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24528
GSE193258,GSE193259_9_v_15_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DMRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.6467
CTCF_A549_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46474
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4115-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.17989
LMSU	CCLE Cell Line Gene CNV Profiles	1.0	1.40044
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.85568
GTEX-P44H-0008-SM-48TDW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
juvenile	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.261964
GSE133087_5_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_UNC0631_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.017231
Mouse - Motor Cortex - Cluster - Layer 6 glutamatergic neuron, intratelencephalon-projecting_1	HuBMAP Azimuth Cell Type Annotations	1.0	null
PMC10528072-NIHMS1928302-supplement-5.xlsx-NEUROD1-target_genes-AANAT_NEUROD1	Rummagene Transcription Factor Associations 2026	1.0	null
organic substance catabolic process	GO Biological Process Annotations 2015	1.0	null
ZNF821	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92802
PIP(18:0/20:4(8Z,11Z,14Z,17Z))	HMDB Metabolites of Enzymes	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXA3_FOXA3	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.867572
LOXIMVI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A57G-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAL 54	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.839915
SIHA	CCLE Cell Line Gene CNV Profiles	1.0	1.78362
HCC2157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.71624
ZNF723	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55487
PIP(16:0/18:0)	HMDB Metabolites of Enzymes	1.0	null
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12509
RNF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57431
ZNF621	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14315
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.24376
SETDB1-19884257-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Lateral ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
hsa-miR-4477a	TargetScan Predicted Conserved microRNA Targets	1.0	0.145356
STK17A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86404
A549_Aurora A Inhibitor I_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0176884
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SAS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
estradiol_homo sapiens_gpl14550_gse35034	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81P-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RVPV-0008-SM-47JYW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
H3K9me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE180185_7_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_Resveratrol_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0154302
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32544
SARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58551
hsa-miR-17	TargetScan Predicted Conserved microRNA Targets	1.0	0.088999
Sarcoma_SARC_TCGA-FX-A3NJ-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193258,GSE193259_2_v_15_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE68156_0_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91421
GSE203131_0_v_1_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CPZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39658
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.0134
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
substance-related disorder	GWASdb SNP-Disease Associations	1.0	0.176168
Brain stem	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
496100438_PCx_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.66617
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A6C5-11A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TIMM44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2015
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.43755
GSE204811,GSE204813_1_v_3_trim29_human	RummaGEO Gene Perturbation Signatures	1.0	null
ECEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.878
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16364
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3NA-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WQUQ-1426-SM-3MJFD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07551
PIP2(16:0/22:2(13Z,16Z))	HMDB Metabolites of Enzymes	1.0	null
neoplasm by anatomical site	GWASdb SNP-Phenotype Associations	1.0	0.048915
PTP4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81906
PIP(18:2(9Z,12Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
PIP(16:0/20:1(11Z)) 	HMDB Metabolites of Enzymes	1.0	null
MDBK cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.981
LCLC103H	CCLE Cell Line Gene CNV Profiles	1.0	1.52047
superficial stratum of r2BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32985
RERF-LC-KJ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Left ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.135
GTEX-R3RS-0008-SM-48FF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828223
NCI-H2172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.928455
Perturb_8306_KO_GALNT2_ERP012063	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
CHK1_KD_GSE54268_665_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
hsa-miR-4704-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
GTEX-OXRK-0826-SM-2HMK7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31051
PIP2(18:0/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
JAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01973
GSE180185_7_v_5_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
E2F6_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WH7G-0426-SM-3NMBJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14614
A549_Crizotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0162712
C1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4462
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NA-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WHWD-0426-SM-3LK83	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80703
alar part of terminal hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.25704
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.085646
GSE183335,GSE183351_1_v_2_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12774775-mmc2.xlsx-PAR_RARG_merge_q5_Narrow_subKO-ENSEMBL_ID_RARG	Rummagene Transcription Factor Associations 2026	1.0	null
PK-45H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.90594
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.864633
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7091-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4PP-0326-SM-33HC4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59338
PI(16:0/20:3(8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
PIP(20:3(5Z,8Z,11Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
hsa-miR-548e	TargetScan Predicted Conserved microRNA Targets	1.0	0.029271
terminal paraventricular area of THyA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53574
GTEX-OHPK-0326-SM-2HMJO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23804
GTEX-T5JC-0008-SM-4DM6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37415
GTEX-TSE9-0008-SM-4DXT8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
PI(20:3(8Z,11Z,14Z)/20:3(8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5709-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_INO-1001_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0177195
hsa-miR-3679-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.226173
GTEX-RU72-0011-R11A-SM-2TF6J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54823
PRIMPOL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21621
GTEX-WRHU-0006-SM-3MJF6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34037
MCF7_ITSA-1_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0307157
GTEX-N7MS-0008-SM-4E3JI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
PIP(18:1(11Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
PI(16:0/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
A549_Roxadustat_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0123759
CAL33	CCLE Cell Line Gene Expression Profiles	-1.0	-1.59901
496100461_PCx_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.02389
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PIP2(18:3(6Z,9Z,12Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
GSE130401_4_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_Belinostat_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0117605
MCF7_CYC116_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0141602
VZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15188
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2066	COSMIC Cell Line Gene CNV Profiles	1.0	2.19301
GSE221327_5_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
CDKN1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7847
FOXA1_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBC1D2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50245
GSE156923_2_v_1_rbmx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09179
MYO10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1172
NBN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06686
NCI-H23	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WFG8-0001-SM-4LVN8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25006
medial mammillary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25227
PI(20:1(11Z)/20:4(5Z,8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
GSE174383_6_v_7_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NDUFA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81253
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NPFF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95415
MCF7_ITSA-1_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0156308
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
GSE228992_0_v_1_mafb_human	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate part of r1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.9959
GSE180525,GSE180528_2_v_0_tbx3_human	RummaGEO Gene Perturbation Signatures	1.0	null
body of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.30753
PI(18:1(11Z)/20:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
GTEX-TML8-0926-SM-4DXSJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22175
PIP(18:0/16:0)	HMDB Metabolites of Enzymes	1.0	null
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
PMC9999213-mmc3.xlsx-DEGs_CSc-DEA_NB_MSC_EC_CSc_vs_NB_CSc_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
LU-134-A	COSMIC Cell Line Gene CNV Profiles	1.0	2.19301
Integral component of the cytoplasmic side of the plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.446
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-2.03432
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7288-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X3Y1-0426-SM-3P5Z4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32021
Perturb_9533_KO_CEP83_SRP379861	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.55476
MCF7_Entinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0168167
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE175787_8_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTF2E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2398
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29655
KCI-MOH1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46474
GSE148494,GSE182513_1_v_0_hoxd13_human	RummaGEO Gene Perturbation Signatures	1.0	null
GATAD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65653
mantle zone of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.99482
hsa-miR-4722-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GSE96649_1_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-MITF_Targets_enrichment-Unnamed_52_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
PI(18:2(9Z,12Z)/20:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
PIP(18:0/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
Perturb_2483_Mut_ESR1_SRP254635	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XGQ4-0326-SM-4GIEE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03474
MOR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.943751
CADOES1	CCLE Cell Line Gene Expression Profiles	1.0	1.43088
TRAF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32787
hsa-miR-625	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
NTAQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54537
G70101JE	GlyGen Glycosylated Proteins	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2964-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH2066	CCLE Cell Line Gene Expression Profiles	1.0	1.61236
NCI-H1734	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00031
GTEX-QDVJ-0426-SM-2I5FW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06738
GSE48812_4_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
external cortical nucleus of inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17083
GSE150669_0_v_3_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SHISA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19031
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8387919-mmc2.xlsx-ST6_NEUROG3-KO_downreg-Supplemental_Table_6_Genes_downregulated_in_NEUROG3-_-_hESC_line_differentiated_to_pancreatic_endocrine_progenitors_d13_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
Entorhinal area, lateral part, layer 2a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21944
RBBP5	ENCODE Transcription Factor Targets	1.0	null
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4103
VZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.71187
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5376
GTEX-RU72-2226-SM-46MUE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09641
RNF146	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28258
GTEX-T5JW-0426-SM-4DM7M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883917
creutzfeldt-jakob disease	GWASdb SNP-Disease Associations	1.0	1.23342
hsa-miR-4659b-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.031759
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.872561
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09354
r2 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32926
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.19115
PI(18:3(9Z,12Z,15Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.18253
MCF7_Temsirolimus_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0152573
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MCF7_INO-1001_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0186223
E2F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3953
PIP2(22:4(10Z,13Z,16Z,19Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
RBM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74511
PMC12706077-44318_2025_598_MOESM21_ESM.xlsx-Dataset_EV19-hKidney_TPP-PISA-Genes_ZNF568	Rummagene Transcription Factor Associations 2026	1.0	null
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PWOO-0426-SM-48TZF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870301
PIP(16:2(9Z,12Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10W-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PI(18:1(11Z)/16:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
A549_Aurora A Inhibitor I_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0169169
ZR75B	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.961673
A549_Hesperadin_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0143264
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7050-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIP2(16:0/16:0)	HMDB Metabolites of Enzymes	1.0	null
PMC9253713-mmc3.xls-sufu_KD_HCC1954_DEGs-Supplementary_Table_2_Differentially_expressed_genes_upon_knockdown_of_SUFU_compared_to_control_in_HCC1954_cells_Related_to_Figure_3_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE233548_2_v_0_plscr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MLLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.94874
intermediate stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74784
PIP(18:1(9Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
GSE181517_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12775252-18_2025_5991_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_2_Up-_and_down-regulated_genes_in_TCF7L2-depleted_EVT_compared_to_control_EVT_TCF7L2	Rummagene Transcription Factor Associations 2026	1.0	null
PI(18:1(9Z)/18:3(9Z,12Z,15Z))	HMDB Metabolites of Enzymes	1.0	null
GSE205163,GSE205164_3_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MRPL14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26972
hsa-miR-515-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.020071
PI(20:3(8Z,11Z,14Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
GSE236502_2_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
A549_Andarine_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0151823
hsa-miR-548a-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.219115
GTEX-OHPM-0326-SM-33HCA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51362
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3872
Lung squamous cell carcinoma_LUSC_TCGA-39-5040-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
prion disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.894179
Acute Myeloid Leukemia_LAML_TCGA-AB-2899-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PI(16:0/20:2(11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
PIP2(18:2(9Z,12Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
CLDN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77896
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-3923-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XPT6-0001-SM-4B64G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30182
hsa-let-7i	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
MCF7_PCI-34051_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0163188
PIP(16:0/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
PIP(20:2(11Z,14Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
Feather bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.65
PMC13138062-mmc7.xlsx-DUGs_ESR1_targets-DUGs_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-3925-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
hsa-miR-3180-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.009975
phosphoric ester hydrolase activity	GO Molecular Function Annotations 2023	1.0	null
PMC9334849-Table_3.xlsx-subcutaneous_adipose_tissue-D1_VS_D9_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
A549_ITSA-1_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0263222
SW948	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64127
ACSL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89805
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-105	TargetScan Predicted Conserved microRNA Targets	1.0	0.193083
PIP2(20:3(5Z,8Z,11Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.7241
ZNF217	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66657
OTUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63499
VZ in subgenual cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.48886
hsa-miR-1305	TargetScan Predicted Conserved microRNA Targets	1.0	0.031759
A549_BMS-754807_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0164444
SERF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37184
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.96545
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6134-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE205163,GSE205164_5_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H748	COSMIC Cell Line Gene CNV Profiles	1.0	2.19301
NDUFB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97147
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QDVN-0008-SM-48U2D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03073
abnormality of blood and blood-forming tissues	GWASdb SNP-Phenotype Associations	1.0	0.052629
GTEX-WEY5-0226-SM-3GIKN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49329
RBPMS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94237
enzalutamide_homo sapiens_gpl570_gse44905	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-1260	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
SMAD4-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Olfactory tubercle, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03157
hsa-miR-548u	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
PIP(16:0/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
A549_INO-1001_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0123261
hsa-miR-410	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
lateral part of preisthmic periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.23006
Perturb_13938_KO_GPR91_SRP366683	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MARF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10461
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PIP2(16:0/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
hsa-miR-106a	TargetScan Predicted Conserved microRNA Targets	1.0	0.088999
hsa-miR-4476	TargetScan Predicted Conserved microRNA Targets	1.0	0.212286
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15948
dorsal cochlear nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.27818
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.125689
SRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33034
AGS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
spi1_17041602_preleukemic_hscs_lof_mouse_gpl1261_gds2411	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.23245
GTEX-UPK5-0226-SM-3GAEV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03535
OELE	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69663
single-organism catabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-XUYS-0005-SM-47JZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
GTEX-OIZG-0008-SM-4E3J2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39273
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.04104
TAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49558
CSNK1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46321
Creutzfeldt-Jakob Disease, Sporadic	DisGeNET Gene-Disease Associations	1.0	null
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983074
PLEKHH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3582
hsa-miR-520b	TargetScan Predicted Conserved microRNA Targets	1.0	0.075559
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13475
FARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87493
MTF2-20144788-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
A549_AG-490_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0135283
GSE195743_1_v_4_lhx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.875754
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
SKMEL1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.68313
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
PRPF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62554
LB647-SCLC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XQ8I-0126-SM-4BOPL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13155
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81A-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FRA1	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-SSA3-0008-SM-47JWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06114
SYCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13939
GTEX-P44H-2426-SM-2XCEJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30687
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
FOXA2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18415
NCI-H1573	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MCF7_PJ34_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.016187
GTEX-VUSG-0008-SM-4KL24	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876695
GSE221742,GSE221743_1_v_0_sipa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WVLH-2926-SM-3MJG5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927068
GSE112962,GSE112963_2_v_1_ddx5_human	RummaGEO Gene Perturbation Signatures	1.0	null
NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6826-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01726
ERCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.96601
H3K4me1_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Genital Diseases, Female	CTD Gene-Disease Associations	1.0	1.30026
POLR2A	ENCODE Transcription Factor Targets	1.0	null
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0722
METTL27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.85017
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86294
A549_Ofloxacin_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0187556
CFAP157	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48509
PIP(20:3(5Z,8Z,11Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
GSE60217_1_v_0_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AFF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34457
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.76643
SHOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14435
LTBR_INHIBITION - 2 Days_GDS2005_729_mouse_Lymph nodes  (MG-430B)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
MCF7_ENMD-2076 L-Tartaric acid_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0326498
Reflex, Abnormal	CTD Gene-Disease Associations	1.0	1.31506
RPRD1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33586
NCIH446	CCLE Cell Line Gene Expression Profiles	1.0	1.4044
Inhibin B complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.928
FAM193B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42225
LLGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13818
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HCC1359	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58578
Uterine endometrium	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PL18	COSMIC Cell Line Gene CNV Profiles	1.0	2.19301
PHLPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1641
ERLEC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63428
Fibrosis	CTD Gene-Disease Associations	1.0	1.19379
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3663-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
IFT20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63764
AIDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34547
isthmus proper	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33878
GSE221327_1_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.85091
ZNF584	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42517
VI	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03424
hsa-miR-4461	TargetScan Predicted Conserved microRNA Targets	1.0	0.02226
GSE109565_12_v_4_glyphosate_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PIP2(16:1(9Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
496100485_PCx_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.081
SUZ12-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
abnormality of leukocytes	GWASdb SNP-Phenotype Associations	1.0	0.098885
C1orf122	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68799
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-335	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
HAS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52291
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3742-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QXCU-0008-SM-48FCH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.824061
MDST8	CCLE Cell Line Gene Expression Profiles	-1.0	-1.7452
PI(18:1(9Z)/20:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
GSE205163,GSE205164_2_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE221327_1_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.56316
FOXA1	ENCODE Transcription Factor Targets	1.0	null
ECC10	CCLE Cell Line Gene Expression Profiles	1.0	2.24898
MCF7_Ofloxacin_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0284627
H4C15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66766
PMC10794847-mmc6.xlsx-PIAS1_KD_up-Table_S5_Genes_differentially_expressed_with_PIAS1_knockdown_in_keratinocytes_cultured_in_the_differentiation_condition_Related_to_Figure_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
r7 part of parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0028
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6482-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
18032706-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
A549_Enzastaurin_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0149681
PMC9882185-media-4.xlsx-Neuron_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-544b	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
lateral group of nuclei, right, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00222
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.837145
KATOIII	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-TSE9-0011-R11A-SM-3DB7N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48902
GSE210101,GSE210114_2_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
PIP(18:0/16:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
GTEX-X261-0926-SM-3NMCY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11537
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5466-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04704
superficial stratum of Pal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07812
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.915717
internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-PX3G-0326-SM-2I3EO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00557
A549_Ramelteon_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0217774
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
GSE205163,GSE205164_5_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVJ-0008-SM-48U2E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07843
MCF7_Amisulpride_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0147574
HS852T	CCLE Cell Line Gene CNV Profiles	1.0	2.18679
hsa-miR-20a	TargetScan Predicted Conserved microRNA Targets	1.0	0.092495
PMC4060771-170289.f1.pdf-391-MEIS1_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7920-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-let-7g	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJMC-0526-SM-3GAE3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50933
GTEX-XOT4-1126-SM-4B66E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898088
recurrent infections	GWASdb SNP-Phenotype Associations	1.0	0.300346
leukemia	GWASdb SNP-Phenotype Associations	1.0	0.255965
MCF7_S-Ruxolitinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0161731
18277965-TableS1b	GeneSigDB Published Gene Signatures	1.0	null
A549_WHI-P154_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0179136
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.6273
PARL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39556
PI(18:0/22:4(7Z,10Z,13Z,16Z))	HMDB Metabolites of Enzymes	1.0	null
METTL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18039
PIP2(18:2(9Z,12Z)/20:3(8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
GTEX-WFG8-0008-SM-4LVN6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01007
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052709
CHRNA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85972
GTEX-WWYW-3026-SM-3NB36	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948442
AR	ChEA Transcription Factor Targets	1.0	null
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PROM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26903
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU182	CCLE Cell Line Gene CNV Profiles	1.0	1.34797
GTEX-NPJ7-0008-SM-4E3JS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.978174
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lyf-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Mouse - Motor Cortex - Cluster - Grp+ Layer 6 glutamatergic neuron, corticothalamic-projecting	HuBMAP Azimuth Cell Type Annotations	1.0	null
central nervous system disease	GWASdb SNP-Disease Associations	1.0	0.211767
GTEX-OHPL-0008-SM-4E3I9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.931474
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.902872
Urinary bladder transitional cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.694
STOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63647
uterine cervix	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.256234
GTEX-WEY5-0426-SM-3GIKT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54817
Perturb_812_OE_TRIB3_SRP262247	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.62404
MOCS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43707
HCC70	CCLE Cell Line Gene CNV Profiles	1.0	1.76619
MYC-27129775-CHIP-SEQ-CORNEA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PIP3(18:0/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
ATP2B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55269
Puberty, Precocious	CTD Gene-Disease Associations	1.0	1.24087
PI(20:4(5Z,8Z,11Z,14Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052596
MHHNB11	CCLE Cell Line Gene Expression Profiles	1.0	1.97176
GTEX-X62O-0826-SM-46MW8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.175
CAL12T	CCLE Cell Line Gene Expression Profiles	1.0	1.64119
Stereocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.848
GTEX-WZTO-2826-SM-3NM8P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00143
upper (rostral) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34126
PMC12623973-41467_2025_64981_MOESM3_ESM.xlsx-downregulated-c0_ACKR4_SCS_ceiling_LEC_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4668-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.026857
Brain Lower Grade Glioma_LGG_TCGA-DU-7304-01A-12R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE227592_8_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051886
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WHSE-0011-R11A-SM-3P5YY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909151
PIP2(22:5(7Z,10Z,13Z,16Z,19Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
GSE188721_3_v_1_mesp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WFG8-0726-SM-3GILP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20205
hsa-miR-3074-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.092495
glis3_19805515_embryonic_pancreas_lof_mouse_gpl1261_gds3812	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.503513
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37152
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HAND1_cust_neg_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
RH-41	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UCHL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50787
TBP	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-33-6737-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_Baricitinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0170903
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HTT-18923047-STHDH-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
U178	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47041
GATA5_KO_GSE47425_50_mouse_lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC7412812-13059_2020_2115_MOESM11_ESM.xlsx-All_H3K27me3-Upregulated_in_SERBP1_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SUCO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58324
VSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8559
GTEX-SUCS-0326-SM-32PLL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74209
MCF7_ITSA-1_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0463256
GTEX-RVPV-0011-R11A-SM-2TF6F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31432
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.247
TCTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85352
PIP2(18:2(9Z,12Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
HDAC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03569
Rectum adenocarcinoma_READ_TCGA-G5-6572-02A-12R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24693
PIP(18:0/20:3(5Z,8Z,11Z))	HMDB Metabolites of Enzymes	1.0	null
PSPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92298
GTEX-NPJ8-0011-R11A-SM-2YUMS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35252
PI(20:4(8Z,11Z,14Z,17Z)/20:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
Pparg::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.9911
CORL279	CCLE Cell Line Gene Expression Profiles	1.0	2.40873
GSE96649_1_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H740	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CAL120	CCLE Cell Line Gene Expression Profiles	1.0	1.78668
MYF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94761
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q6-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST	ChEA Transcription Factor Targets	1.0	null
VIPAS39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30656
Esophagus - Mucosa	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.603537
MCF7_AZ 960_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0203328
WDR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19139
SIN3A	ENCODE Transcription Factor Targets	1.0	null
GSE202434,GSE202438_15_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100448_TCx_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.00038
GSE48812_4_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_MK-0752_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0185545
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
hsa-miR-3163	TargetScan Predicted Conserved microRNA Targets	1.0	0.088999
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837392
PIP2(18:0/16:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
GSE202434,GSE202438_7_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-135b	TargetScan Predicted Conserved microRNA Targets	1.0	0.026857
Perturb_9677_KD_PIAS1_SRP295152	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.49848
MCF7_Ki8751_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0129093
LCLC-103H	COSMIC Cell Line Gene CNV Profiles	1.0	2.19301
EN2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7234
CTCF_fibroblast of pulmonary artery_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PI(16:2(9Z,12Z)/22:3(10Z,13Z,16Z))	HMDB Metabolites of Enzymes	1.0	null
Sarcoma_SARC_TCGA-DX-A48J-01A-21R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.94876
Lung squamous cell carcinoma_LUSC_TCGA-43-6773-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE168233_0_v_1_setdb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
HMGA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22656
GTEX-QVJO-0011-R9A-SM-2S1QH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11282
CREB3L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86677
mantle zone of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17508
Exopher	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.736
subcuneiform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50796
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.884917
GSE102870_7_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4244-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Junctional membrane complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.2
HELZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55233
MCF7_CEP-33779_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0123119
A549_Aurora A Inhibitor I_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0138745
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74555
Integument	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34894
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18709
isthmic liminal reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13689
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3JV-01A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_PCI-34051_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0303814
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.824536
PI(20:0/20:4(5Z,8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
PC14	CCLE Cell Line Gene CNV Profiles	1.0	1.6493
GTEX-S7SE-0011-R11A-SM-2XCDD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37301
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18323
GTEX-SNMC-0008-SM-4DM5A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1AC-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044255
ETHE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28058
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H290	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC12774775-mmc2.xlsx-PAR_RARG_merge_q5_Narrow_subKO-Gene_Symbol_RARG	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_CUDC-907_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00794736
MLF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86597
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.29016
H3K27me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCIH2009	CCLE Cell Line Gene CNV Profiles	1.0	1.80531
hsa-miR-559	TargetScan Predicted Conserved microRNA Targets	1.0	0.248923
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1809
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PI(18:2(9Z,12Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
nicotine dependence	GWASdb SNP-Disease Associations	1.0	0.988534
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.61266
PIP(18:0/16:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157F_vs_MSX1-Gene_id_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-30c	TargetScan Predicted Conserved microRNA Targets	1.0	0.226173
ChIP_SUZ12_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PI(18:2(9Z,12Z)/20:3(8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
ATM_KD_GSE54268_661_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
MCF7_Tofacitinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0155499
GTEX-U8T8-0008-SM-4DXSP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34339
ZNF560	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96584
SLCO4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9602
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6939-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_AICAR_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0163336
GSE238018_3_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S32W-1226-SM-4AD67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45146
DRD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29487
ARHGAP21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57361
SNU886	CCLE Cell Line Gene Expression Profiles	1.0	1.58052
PMC4595011-pgen.1005555.s003.xlsx-BPTF_UP-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
PIP(18:1(9Z)/20:3(5Z,8Z,11Z))	HMDB Metabolites of Enzymes	1.0	null
Edinger-Westphal nucleus (accessory oculomotor nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.903812
RMND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51445
hsa-miR-548d-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.205675
ACOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34019
Brain Lower Grade Glioma_LGG_TCGA-E1-5302-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SHSY5Y	CCLE Cell Line Gene Expression Profiles	1.0	3.40776
shell of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07493
PMC11196642-41419_2024_6838_MOESM5_ESM.xlsx-Supplementary_Table_3-Supplementary_Table_3_Differentially_expressed_genes_in_RNA-seq_between_MCF7_SMAD4-KO_and_parental_groups_SMAD4	Rummagene Transcription Factor Associations 2026	1.0	null
PIP(16:2(9Z,12Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
A549_Danusertib_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.014842
SCN4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18705
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.68809
GTEX-P78B-0008-SM-48TE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
EMC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01599
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PIP(18:1(11Z)/20:3(8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
dorsolateral IC periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16672
H3K27me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HADHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67398
PI(18:2(9Z,12Z)/20:0)	HMDB Metabolites of Enzymes	1.0	null
MZ in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30932
Medial septal complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30552
MRPL17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6672
PMC12176927-125_2025_6424_MOESM1_ESM.pdf-26-DMBX1_DMBX1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S95S-0002-SM-3NM8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45245
hsa-miR-520a-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.062888
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052708
GSE138841_0_v_1_trim6_human	RummaGEO Gene Perturbation Signatures	1.0	null
PI(18:2(9Z,12Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19938
NUPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57271
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70K-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100307_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.2571
A549_Divalproex Sodium_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0139806
PI(22:5(4Z,7Z,10Z,13Z,16Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
PIP(22:4(7Z,10Z,13Z,16Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860689
NB-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
COL8A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47628
MCF7_Tazemetostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0195044
GTEX-S3XE-0426-SM-3K2AC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.981511
medial basal reticular formation of m1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05478
TMK-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.19301
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.928003
Medial amygdalar nucleus, posterodorsal part, sublayer a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12947
VZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.76121
FKBPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37352
PI(16:0/22:2(13Z,16Z))	HMDB Metabolites of Enzymes	1.0	null
EMILIN complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.857
GTEX-POMQ-0326-SM-2I5FO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27707
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053503
Male infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.32
ACSBG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99536
Thyroid primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.776
SW900	COSMIC Cell Line Gene CNV Profiles	1.0	2.19301
MCF7_ENMD-2076 L-Tartaric acid_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0325805
ASAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74936
A549_2-Methoxyestradiol_10然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0127205
HCC1500	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.18911
A549_BMS-911543_1然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0184605
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A3DJ-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hematological neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.165282
hsa-miR-548ak	TargetScan Predicted Conserved microRNA Targets	1.0	0.205675
ventral lateral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28088
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5680-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7608835-aba3058_Table_S3.xlsx-324_RING1B-FLI1_notH2Aub-Genes_containing_RING1B_EWSR1-FLI1_peaks_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.866224
PIP(18:0/20:3(8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
GTEX-OHPN-0011-R11A-SM-2I5FM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885841
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EH-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LDB1-21186366-BM-HSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_JQ1_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0187953
PMC6932815-ppat.1007634.s015.xlsx-ST5_DGE_ELF1-R8AvIFN48-mock_lfc-external_gene_name_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
SNU81	CCLE Cell Line Gene CNV Profiles	-1.0	-2.11643
hsa-miR-2116	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3732-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMC4-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PIP2(20:4(5Z,8Z,11Z,14Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
PIP2(18:1(11Z)/20:3(8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A2QR-11A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LDB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27646
LK-2	COSMIC Cell Line Gene CNV Profiles	1.0	2.19301
ZMIZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86025
I-II	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17104
amygdaloid complex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.38237
GTEX-XUJ4-0626-SM-4BOOO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04606
PIP(18:2(9Z,12Z)/20:3(8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.039354
PRICKLE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39589
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
catabolic process	GO Biological Process Annotations 2015	1.0	null
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MB-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100407_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.44771
PI(16:2(9Z,12Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
PI(18:1(11Z)/18:3(6Z,9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
MYBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79108
PI(16:0/22:5(4Z,7Z,10Z,13Z,16Z))	HMDB Metabolites of Enzymes	1.0	null
GTEX-V1D1-0003-SM-3NMDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08159
GSE214382,GSE214383_4_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4540202-cddis2014370x2.xls-Sheet1-Table_S2_MEIS2-responsive_genes_MEIS2	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7DV-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-6672-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIP2(18:1(11Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8411-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_Decitabine_1然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0181953
Entorhinal area, medial part, dorsal zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55261
PI(18:1(9Z)/20:3(5Z,8Z,11Z))	HMDB Metabolites of Enzymes	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7248-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
u	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.502
lipid catabolic process	GO Biological Process Annotations 2015	1.0	null
body of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13047
hsa-miR-624	TargetScan Predicted Conserved microRNA Targets	1.0	0.050854
liminal periaqueductal gray of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36059
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.10916
GSE219274,GSE219276_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PIP2(18:1(9Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7996-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Globus pallidus, external segment	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01409
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.75209
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6I0-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM143	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05978
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.951644
GTEX-QVJO-1325-SM-2S1QX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09198
Ventral anterior-lateral complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54306
organ system cancer	GWASdb SNP-Disease Associations	1.0	0.066154
GTEX-PSDG-0926-SM-2I5FP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34831
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051802
central amygdaloid nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.44858
lateral part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36388
PIP(18:1(11Z)/20:4(8Z,11Z,14Z,17Z))	HMDB Metabolites of Enzymes	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-R3-A69X-01A-22R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
schizophrenia	GWASdb SNP-Disease Associations	1.0	0.693888
inner SZ in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.928405
hsa-miR-548w	TargetScan Predicted Conserved microRNA Targets	1.0	0.205675
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
PI(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
lipid metabolic process	GO Biological Process Annotations 2015	1.0	null
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NR2C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32181
PI(20:3(8Z,11Z,14Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
GSE149903_3_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SLC7A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85958
EZH2_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NTMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92402
DGAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44129
PIP2(16:0/20:3(5Z,8Z,11Z))	HMDB Metabolites of Enzymes	1.0	null
PIP2(16:0/20:2(11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
CEBPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71397
GSE175787_4_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
A549_SRT2104_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0318761
PIP2(18:1(11Z)/20:4(5Z,8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
GTEX-OHPK-2426-SM-3MJGH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14707
537 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.839915
hsa-miR-4301	TargetScan Predicted Conserved microRNA Targets	1.0	0.226173
MCF7_Trichostatin A_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.015061
Supramammillary nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38127
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PI(20:2(11Z,14Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PIP2(18:1(9Z)/18:3(9Z,12Z,15Z))	HMDB Metabolites of Enzymes	1.0	null
H3K27me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PI(18:1(9Z)/18:3(6Z,9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
hsa-miR-4471	TargetScan Predicted Conserved microRNA Targets	1.0	0.034317
FIH_Deficiency_GDS3769_511_mouse_Immortalized embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE165939_2_v_1_poldip2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hmx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.5783
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7255-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QG-01A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MSC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28932
LHX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61447
ACADM_KO_GDS4546_512_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K27me3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE135352_6_v_4_napabucasin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_MK-0752_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0193713
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-NEUN_UNIQUE_DYS_GENES-PAX6_TLE_vs_TL_log2FoldChange_1_padj_0_1_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
BTD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05649
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PIP(20:2(11Z,14Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
PIP(18:1(9Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
p3 portion of parabrachial pigmented nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0199
GSE248858_6_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PI(18:0/16:0)	HMDB Metabolites of Enzymes	1.0	null
r1 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.12995
Orbital area, medial part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17697
MCF7_Roxadustat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0103965
ACAD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03574
PIP2(18:1(11Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
KDELR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53265
RBM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53703
head of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.42876
IFT25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0248
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.58437
UMC-11	COSMIC Cell Line Gene CNV Profiles	1.0	2.19301
PIP(16:0/20:4(5Z,8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
A549_Iniparib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0182144
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.872392
NCAPD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13215
GTEX-WFON-0326-SM-3GIKX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72837
GTEX-TKQ2-0004-SM-3NMAC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.201
MITF	ChEA Transcription Factor Targets	1.0	null
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7382
rostral secondary prosencephalon	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81142
NANOS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61707
PI(20:2(11Z,14Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
VZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.979967
PIP3(18:1(11Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
A549_Momelotinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0128365
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PIP(18:2(9Z,12Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
ATP6V1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01301
heparin_homo sapiens_gpl570_gse12710	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-373	TargetScan Predicted Conserved microRNA Targets	1.0	0.065994
GTEX-X261-0011-R11A-SM-4E3JY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31435
inner SZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0204
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.90123
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.896365
PI(18:1(9Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
LARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04288
Partington syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.098
Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intrinsic component of the cytoplasmic side of the plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.356
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.07295
mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.117449
ZNF92	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84733
hsa-miR-222	TargetScan Predicted Conserved microRNA Targets	1.0	0.006367
hsa-miR-4687-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.004732
PMC9942993-pone.0281645.s002.xlsx-non-AR_as_all_as_gained-ENSEMBL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9882185-media-4.xlsx-Neuron_KD-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05039
A549_Ruxolitinib_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0183472
GSE250518_0_v_2_trpm3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SKLU1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.27496
VIIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.898844
hydrolase activity, acting on ester bonds	GO Molecular Function Annotations 2015	1.0	null
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PIP(18:1(15Z)/20:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
A549_Tazemetostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0166764
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Ventral tegmental area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08789
GTEX-U3ZH-0326-SM-3DB7A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49642
Acute Myeloid Leukemia_LAML_TCGA-AB-2938-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
synapse	SynGO Synaptic Gene Annotations	1.0	null
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.935828
PIWIL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84481
TFAP2C-20629094-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
METTL7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95019
Prion disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.107
intermediate stratum of r1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.9764
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49642
retromammillary area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.43468
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_PD173074_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0219948
MAPK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4306
Simple lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02816
outer SZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.829414
SLC25A33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.207
m2 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65559
GTEX-WHPG-0826-SM-3NMBF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956469
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.835796
PI(22:5(4Z,7Z,10Z,13Z,16Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
PIP(22:5(7Z,10Z,13Z,16Z,19Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
PIP2(16:0/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
hsa-miR-544	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Atrium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.017
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
PIP2(20:4(8Z,11Z,14Z,17Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
A549_Lomustine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.015812
hsa-miR-548j	TargetScan Predicted Conserved microRNA Targets	1.0	0.199275
mRNA_GADD45A_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
DLGAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16319
hsa-miR-1280	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
REST_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FSTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77051
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A42K-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4733-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.226173
GTEX-QEL4-0926-SM-3GAD1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22015
PMC7889611-41467_2021_21346_MOESM10_ESM.xlsx-High_TSA_score_correlations-Supplementary_Data_6_Genes_with_expression_that_positively_correlate_with_a_high_TSA_score_in_AIRE_and_corneocyte-like_mTECs_AIRE	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
G120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.915717
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2441
AGAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63847
hsa-miR-22	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
HCN channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.594
GTEX-TMZS-0008-SM-47JWM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.930342
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10534
NRN1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66505
ARPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3377
ventral tegmental area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.991977
hsa-miR-617	TargetScan Predicted Conserved microRNA Targets	1.0	0.065994
PIP2(16:0/16:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00578
EHMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92291
Vocal fold	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.774
midbrain reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.39809
FOXM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5293
hsa-miR-4423-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.37496
GTEX-NPJ8-2626-SM-2D7W2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891343
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.43749
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PIP(20:0/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
Brain ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
precentral gyrus, right, bank of the central sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.855309
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.870023
hsa-miR-519b-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.017945
SKMES1	CCLE Cell Line Gene Expression Profiles	1.0	1.51486
GTEX-U3ZN-1426-SM-3DB87	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06154
GTEX-V955-0004-SM-3NMDH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22048
Parastrial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06212
A549_Tazemetostat_10然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0145484
VZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27815
PI(18:3(9Z,12Z,15Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
hsa-miR-302a	TargetScan Predicted Conserved microRNA Targets	1.0	0.069137
GSE135244_0_v_1_trdmt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
periventricular stratum of the PBC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01183
E2F6	ENCODE Transcription Factor Targets	1.0	null
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3255	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ALG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97493
SUMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40889
GTEX-N7MT-1226-SM-2D7W4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16813
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04887
Brain Lower Grade Glioma_LGG_TCGA-HT-7482-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KPNYN	CCLE Cell Line Gene Expression Profiles	1.0	1.86889
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.84609
A549_SRT2104_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0232687
MCF7_BMS-265246_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0153735
GTEX-XMD3-2326-SM-4AT5H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872227
Midbrain, behavioral state related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40185
spleen	GTEx Tissue Gene Expression Profiles	-1.0	-1.00691
GTEX-XLM4-2026-SM-4AT4X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10864
GTEX-XBEW-0002-SM-4AT5O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26786
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
LRFN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41026
GTEX-P4PP-2426-SM-3P61L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64825
PRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89043
PIP2(20:3(5Z,8Z,11Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
hsa-miR-592	TargetScan Predicted Conserved microRNA Targets	1.0	0.115091
GTEX-P4QT-0008-SM-48TDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37487
GTEX-R55E-0526-SM-2TC6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.893399
Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z6-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHKA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48959
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35635
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.083183
superficial stratum of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29526
GTEX-XPT6-0126-SM-4B65S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10104
nose	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.621024
GSE124932_2_v_1_sarm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CBR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49277
MCF7_CYC116_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0136249
Lung adenocarcinoma_LUAD_TCGA-05-4425-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE144231_4_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NPIPB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60409
hsa-miR-1278	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5451-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE130246_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_Andarine_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0197548
MRGPRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44295
PI(20:4(8Z,11Z,14Z,17Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
PMC7412812-13059_2020_2115_MOESM11_ESM.xlsx-Overlap-Upregulated_in_SERBP1_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WYJK-1026-SM-3NM8W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6189
hsa-miR-302b	TargetScan Predicted Conserved microRNA Targets	1.0	0.069137
hematologic cancer	GWASdb SNP-Disease Associations	1.0	0.196765
PIP(16:1(9Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5676-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4721	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
RRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26082
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-4103-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Supraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.74617
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0143
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.8178
A549_GSK1070916_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0189186
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8787
G118	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.861659
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-gene_id_x_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4670-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.099701
Creutzfeldt-Jakob Disease	DisGeNET Gene-Disease Associations	1.0	null
acute leukemia	GWASdb SNP-Phenotype Associations	1.0	0.375889
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CF-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03365
GSE102870_1_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_JNJ-7706621_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0235127
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.88869
HCT15	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56019
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
C11orf68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.943
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10772
GSE261177_0_v_1_tnfrsf12a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_JNJ-7706621_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0118851
PIP(18:1(9Z)/18:3(6Z,9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
GSE228894_0_v_2_rnmt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.26503
intermediate stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33124
H3K27me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Ruxolitinib_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0159196
hsa-miR-548z	TargetScan Predicted Conserved microRNA Targets	1.0	0.02226
Perturb_15377_KD_DAXX_SRP058098	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
NAGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98583
GTEX-PWO3-1026-SM-2I5F2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967761
PMC9950457-mmc3.xlsx-GRHL2_overexpression_UP-gene_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EL-11A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE174701_4_v_8_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.915717
CUL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23198
hydrolase activity	GO Molecular Function Annotations 2015	1.0	null
A549_Alisertib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0211604
A549_Alisertib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.013907
ZNF148	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97339
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.16837
GTEX-TKQ1-0003-SM-3NMAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.948668
PI(16:0/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
DDX51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13459
ZFTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67593
PIP(18:1(11Z)/16:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
hsa-miR-942	TargetScan Predicted Conserved microRNA Targets	1.0	0.002088
GTEX-RU72-2926-SM-2TF66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19439
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_60_AR	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-597	TargetScan Predicted Conserved microRNA Targets	1.0	0.085563
GSE193258,GSE193259_2_v_8_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.084923
GTEX-X4XX-0011-R11A-SM-46MWQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14173
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1745
NR2C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2715
TMEM259	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49761
PIP(16:0/22:4(7Z,10Z,13Z,16Z))	HMDB Metabolites of Enzymes	1.0	null
hsa-miR-3194-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
PIP2(16:2(9Z,12Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
Perturb_8992_KD_PAX9_SRP407074	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-15.8722
LTBR_INHIBITION - 35 Day_GDS2005_732_mouse_Lymph nodes  (MG-430B)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
A549_ZM 447439_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.024158
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
GTEX-PLZ4-1326-SM-2S1O7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949185
PIP(22:3(10Z,13Z,16Z)/16:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
RAD21_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.941973
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.894493
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE128054_1_v_0_myt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEFF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5636
PI(18:3(6Z,9Z,12Z)/22:3(10Z,13Z,16Z))	HMDB Metabolites of Enzymes	1.0	null
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.99139
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056819
PIP(20:2(11Z,14Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
A549_Celecoxib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0142284
GSE121809_1_v_0_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NTS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79227
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
IPO9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22091
SNTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20552
GSE180525,GSE180528_1_v_0_tbx3_human	RummaGEO Gene Perturbation Signatures	1.0	null
CCNF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89472
RBM39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82096
Mucosa	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTF2-20144788-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.957295
Phosphatidylinositol-3,4,5-trisphosphate	HMDB Metabolites of Enzymes	1.0	null
Entorhinal area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35016
hsa-miR-4279	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
GSE101239_4_v_6_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MAZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30714
CORL311	CCLE Cell Line Gene Expression Profiles	1.0	1.88499
A549_ENMD-2076_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0237007
PMC12827430-41467_2025_67591_MOESM6_ESM.xlsx-Supplementary_Figure_15l-FOSL2_ChIP_WT-exclusive_genes_FOSL2	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4458	TargetScan Predicted Conserved microRNA Targets	1.0	0.31417
Liver hepatocellular carcinoma_LIHC_TCGA-UB-AA0V-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIP2(18:1(9Z)/20:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
Kidney - Medulla	GTEx Tissue Gene Expression Profiles 2023	1.0	3.94893
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.0544
ID4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70678
GSE180185_7_v_8_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4324	TargetScan Predicted Conserved microRNA Targets	1.0	0.069137
r6 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24746
METTL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44342
Pancreatic alpha cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.06
DIXDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55205
GTEX-S7SE-2526-SM-2XCDL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01539
A549_PHA-680632_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0163855
GTEX-N7MS-2526-SM-2D7W3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922848
H4K20me1_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC8350598-NIHMS1728503-supplement-Table_S3.xlsx-Downregulated_by_SMAD4-Gene_Symbol_SMAD4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE195743_3_v_4_lhx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BD-A2L6-11A-21R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4595011-pgen.1005555.s003.xlsx-BPTF_UP-regulated-Gene_name_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U3ZH-0002-SM-3NMDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
93T449	DepMap CRISPR Gene Dependency	1.0	23.4673
SHOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.167
SLC35F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54648
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PIP(20:4(8Z,11Z,14Z,17Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
hsa-miR-1263	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
PMC9376070-41419_2022_5157_MOESM18_ESM.xlsx-Sheet1-Table_S4_Differentially_expressed_genes_of_HNRNPC-KD_and_NC_cells_identified_in_the_RNA-seq_analysis_AR	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-651	TargetScan Predicted Conserved microRNA Targets	1.0	0.078844
sno(s)RNA-containing ribonucleoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.858
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5712-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARL4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33912
GTEX-RNOR-0826-SM-2TF5C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965253
NCIH23	CCLE Cell Line Gene CNV Profiles	1.0	1.43381
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28251
phosphoric diester hydrolase activity	GO Molecular Function Annotations 2015	1.0	null
Sarcoma_SARC_TCGA-FX-A2QS-11A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE184902_4_v_1_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QVUS-0008-SM-447AY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_PCI-34051_10然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0182108
H3K4me1_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M5-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral part of m2A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23197
Learning Disorders	CTD Gene-Disease Associations	1.0	1.32132
PFKL_OE_GDS1980_203_mouse_dermal fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02145
ANKRD52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45422
AQP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50822
PI(18:1(11Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
disease of cellular proliferation	GWASdb SNP-Disease Associations	1.0	0.059964
reticular formation of basal m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.3199
NFU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5117
CDK2AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48942
FKRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59512
CREB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94741
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Synapse	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.7406
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4619-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PIP(18:1(11Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
PIP2(18:1(9Z)/20:3(8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
RTL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.03407
UOK101	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42433
SMAD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74283
terminal hypothalamus (rostral hypothalamus)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.17966
RASSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02015
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25336
hsa-miR-221	TargetScan Predicted Conserved microRNA Targets	1.0	0.004732
GSE129241_1_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
SUZ12	ChEA Transcription Factor Targets	1.0	null
NCI-H520	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE224096_3_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XV7Q-0008-SM-4BRWL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06105
TCF4	MotifMap Predicted Transcription Factor Targets	1.0	null
KMT2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51715
Brain Lower Grade Glioma_LGG_TCGA-DU-7007-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE113005_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE140965_2_v_4_mybpc3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Medial cortex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.562
HNRNPDL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11452
mantle zone of isBL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.9038
PI(16:0/16:0)	HMDB Metabolites of Enzymes	1.0	null
GSE205163,GSE205164_5_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.864707
hsa-miR-4768-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GSE171352_2_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
INTS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33066
GSE242333_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
basointermediate isthmic reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.01177
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
preoptic region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.27324
MCF7_TAK-901_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0147642
hsa-let-7e	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
inner SZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25258
PI(20:3(5Z,8Z,11Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
MCF7_Gandotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0153977
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE171837_3_v_1_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PIP(18:1(9Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
HOXA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83135
PI(16:1(9Z)/16:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
A549_TMP195_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0158549
PMC9170821-JCMM-26-3183-s001.xlsx-Astro_DAPI_ERG_VaDadj_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
RASA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47658
heart_5b	HPA Tissue Sample Gene Expression Profiles	1.0	1.66236
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.50062
PIP2(18:1(9Z)/20:4(5Z,8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
HT1197	CCLE Cell Line Gene Expression Profiles	1.0	1.46936
GSE174701_1_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
SOX7_OE_GDS3300_123_human_HESC (CA1 and CA2)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ZNF263	ENCODE Transcription Factor Targets	1.0	null
inner SZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06461
Mesothelioma_MESO_TCGA-NQ-A57I-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50999
PI(18:2(9Z,12Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7485-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_Sorafenib Tosylate_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0188418
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93484
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.979082
DCAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56477
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.087
H3K4me1_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TSPAN17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65988
TRIOBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37965