association	dataset	threshold value	standardized value
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7059-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K31230200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80688
PMC9314667-Table_1.xlsx-Regulons-MITF_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
CEBPD_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE125782_3_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Parasubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07053
GSE183251_4_v_0_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
17483311-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
GSE213219_2_v_3_st3gal3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE116810_5_v_4_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC11979751-table_s1_trajectoryderivation_elad055.xlsx-Cluster_DE_Genes_Summary-Cluster_2_AP2_Down_GTF3A	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K62418398	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15316
GSE133516_0_v_6_kat7_human	RummaGEO Gene Perturbation Signatures	1.0	null
CD4_Naive_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.0008
rosiglitazone-5230	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888724
Lung adenocarcinoma_LUAD_TCGA-38-4627-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
magnocellular interstitial nucleus of the posterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56707
GTEX-QV31-0008-SM-447AT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994695
CRCGN014_HEPG2_3H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.12225
GSE143406_1_v_0_carfilzomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNU1272	CCLE Cell Line Gene CNV Profiles	-1.0	-2.01985
STAT3	ChEA Transcription Factor Targets	1.0	null
GSE121824,GSE121826_0_v_8_scaf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.84721
GSE144443_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30471
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05118
GSE161295_0_v_5_cdk8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COLO205	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.75156
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-D_ATF4-def_vs_HCT116_Tg2-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.64394
GTEX-S4Z8-0226-SM-4AD5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2853
BRD-A14842104	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36583
GTEX-OIZI-0626-SM-2XCEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93165
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.65315
BRD-K02610196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01485
molecular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69287
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6017-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11227377-2506586.f2.pdf-8-ARID5A_ARID5A	Rummagene Transcription Factor Associations 2026	1.0	null
bezafibrate-2630	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.98424
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE190186,GSE190188_0_v_10_apoe_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TKQ2-0008-SM-4DM5L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08632
GATA3	ENCODE Transcription Factor Targets	1.0	null
BA-84-WN26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.230571
CRCGN017_MCF10A.WT.HP_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5072
Blood cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RBBP5	ENCODE Transcription Factor Targets	1.0	null
OSRC2_KIDNEY	CCLE Cell Line Proteomics	1.0	5.43579
BRD-A80705936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74112
CRCGN011_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.79625
KG-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.908316
TAL1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CBX3	ENCODE Transcription Factor Targets	1.0	null
periventricular stratum of m2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02348
GSE153354_0_v_1_tcf19_human	RummaGEO Gene Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.86634
zomepirac-6815	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11678
monocrotaline-7127	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain - Anterior cingulate cortex (BA24)	GTEx Tissue Gene Expression Profiles 2023	1.0	2.98309
phenazone-1489	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
septum (resp epith)	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.37108
GTEX-Q734-2026-SM-3GADA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.869003
Secretory vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
RUNX2-24655370-MC3T3E1-MOUSE-BONE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.09535
CTCF_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE93309_5_v_3_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
chr15_64873237_C_T_b38	GTEx eQTL 2025	1.0	1.5544
posterior (caudal) superior temporal cortex (area 22c)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.976658
GSE153124_4_v_3_dsg2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PU.1-20513432-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
FB-49-NW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.364684
RING1B-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
astemizole-6807	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE221020,GSE221023_2_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K61029307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20508
florfenicol-6460	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1072
tiratricol-2259	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
tolazoline-1918	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-RNOR-1426-SM-48FDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24288
15955831-SuppTable5	GeneSigDB Published Gene Signatures	1.0	null
PMC9195629-Table1.xlsx-Supplementary_Table_1-JUN_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
Primary somatosensory area, upper limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39484
Mewo	GDSC Cell Line Gene Expression Profiles	1.0	1.6919
SK-MEL-30	GDSC Cell Line Gene Expression Profiles	1.0	1.63667
GSE255680_1_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25575
AC-30-XU83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.365698
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.0952
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.545
Lung squamous cell carcinoma_LUSC_TCGA-22-4593-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hemorrhage	CTD Gene-Disease Associations	1.0	1.23712
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GAK	GDSC Cell Line Gene Expression Profiles	1.0	1.44479
GTEX-Q2AH-1826-SM-2S1Q2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.923331
APP	Pathway Commons Protein-Protein Interactions	1.0	null
SLC9A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27452
GSE198380_0_v_1_phgdh_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc_18Hour_None_GSE43204	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.44366
GSE199899_4_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE131649_6_v_0_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE135030_11_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:A14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.58174
stratum pyramidale of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00107
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HL-60	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	3.45334
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0454
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
GSE227415_1_v_0_ucp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE155305_2_v_0_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
iobenguane-2878	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58181
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.993441
Perturb_17044_KD_IRF4_SRP201887	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03789
tonzonium bromide-5678	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K00020149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81555
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09055
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58138
lower dorsal perifornical nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4907
Cuticular plate	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.667
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4728-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE102486,GSE102490_1_v_5_setdb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE178255_1_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE110178_5_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21672
Weight Loss	CTD Gene-Disease Associations	1.0	1.35821
GTEX-S3XE-0526-SM-4AD4G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.87347
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5545-01A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19O-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-6143-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE103068_5_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
r5 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39318
GSE234514,GSE234516_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SP1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RFC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71087
GTEX-NL3H-0011-R11A-SM-2I3E6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25202
GSE184884_4_v_1_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H2373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03825
MELHO	CCLE Cell Line Gene Expression Profiles	1.0	1.37289
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.476
EE-03-SG02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.503421
PMC8905236-mmc2.xlsx-Table_S9-Table_S9_Differentially_regulated_genes_in_SPI1_high_vs_low_group_in_TCGA_GBM_dataset_SPI1	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15767
BRD-K22683888	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28835
ficolin-1-rich granule	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
etacrynic acid-5742	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.999952
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.65725
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE112860_9_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SubthalamicNucleus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.858181
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ZC3H11A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K93866368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.50855
cyproheptadine-1938	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K53612668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33224
dilazep-2294	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-RWS6-2126-SM-2XCAV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1461
GTEX-WYVS-2326-SM-3NMAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77324
Pleckstrin homology-like domain	InterPro Predicted Protein Domain Annotations	1.0	null
JMSU1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59209
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.67216
EE-98-PF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.256353
BRD-K36084688	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13376
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4255
harman-4408	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
496100500_PCx_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.14382
PMC12774775-mmc2.xlsx-PAR_RARG_merge_q5_Narrow_subKO-ENSEMBL_ID_RARG	Rummagene Transcription Factor Associations 2026	1.0	null
GSE213588_10_v_7_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cingulate gyrus, retrosplenial part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.837011
IRF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GE-53-SM76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.434778
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4771-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K26631178	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6202
LY-294002-461	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Erythroleukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K05957858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01268
GSE138863_2_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
glis2_17618285_kidney_lof_mouse_gpl2897_gds2817	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.0E-6
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K88128293	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41989
Atf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.5305
KYSE450_OESOPHAGUS	CCLE Cell Line Proteomics	1.0	3.909
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04894
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_LF_species_not_found_in_common_genes_of_R_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
JNK3	Kinase Library Serine Threonine Kinome Atlas	1.0	null
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06978
Perturb_429_KD_EHF_SRP049988	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
HDAC6	ENCODE Transcription Factor Targets	1.0	null
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5857
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TP63	ChEA Transcription Factor Targets	1.0	null
PMC6571000__F6	PFOCR Pathway Figure Associations 2023	1.0	null
molecular layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22582
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07091
GSE184210_0_v_1_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE228162_2_v_5_nr2f6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3537
SNU489	CCLE Cell Line Gene Expression Profiles	1.0	1.77079
GSE201309_4_v_7_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100461_PCx_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.13383
624 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.45284
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.976855
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43951
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
DENND1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83126
lidocaine-1917	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HMGN3	ENCODE Transcription Factor Targets	1.0	null
BRD-K39192716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15943
GSE74528_0_v_1_trex2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
AA-23-FM46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.789656
PMC6332659__F3	PFOCR Pathway Figure Associations 2024	1.0	null
Perturb_1606_KO_Tnfaip3_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.13938
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SH3KBP1	Pathway Commons Protein-Protein Interactions	1.0	null
LOVO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
parolfactory gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.921925
GTEX-WYJK-1726-SM-3NM9U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.1929
BRD-A71833059	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27127
inferior frontal gyrus, triangular part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.834248
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14877
TP53	ChEA Transcription Factor Targets	1.0	null
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.888715
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAFK	ENCODE Transcription Factor Targets	1.0	null
GTEX-TSE9-0526-SM-3DB7Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29411
spleen_3d	HPA Tissue Sample Gene Expression Profiles	1.0	1.66302
isoflupredone-5545	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC12774775-mmc2.xlsx-PAR_RARG_merge_q5_Narrow_subKO-Gene_Symbol_RARG	Rummagene Transcription Factor Associations 2026	1.0	null
LY-294002-429	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
A172	GDSC Cell Line Gene Expression Profiles	1.0	1.86612
GTEX-XGQ4-0226-SM-4GIDS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64382
Prestwick-864-4113	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
QF-71-QI30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.78462
Ebolavirus(ZEBOV)_6hr_Macrophage_22028943_GSE31747	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.96366
HCC70	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K48448518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02624
cefazolin-3426	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE213588_8_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KARPAS-422	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.42253
GSE169571_5_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Rootlet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.526
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GSE174498,GSE174500_3_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.27862
GTEX-P4QS-1626-SM-2S1NH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16614
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YE-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of mammary gland_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5371
CRCGN016_MCF10A.TP53.M_24H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.18646
karpas707	HPA Cell Line Gene Expression Profiles	1.0	1.63052
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JD-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWN1-0226-SM-2S1OZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871623
NCIH322	CCLE Cell Line Gene CNV Profiles	1.0	2.78033
BRD-K23762204	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09824
monorden-449	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
naproxen-5457	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K75844518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04328
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXP2_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE218949_0_v_1_cep20_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07632
GSE154074_1_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE162575,GSE162609_3_v_2_tfe3_human	RummaGEO Gene Perturbation Signatures	1.0	null
mantle zone of PSPa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00382
spleen_3c	HPA Tissue Sample Gene Expression Profiles	1.0	1.42905
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.893696
GSE213588_10_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.37536
TAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A148-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE186460_0_v_2_baricitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ACHN	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.28244
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.08387
BAS-012416453-6880	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
IRAK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10742
GSE148321,GSE169423_0_v_1_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PBX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64347
dihydroergocristine-7275	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
dimenhydrinate-7431	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCIH2029	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39192
trim28_23493425_cd71pluster119plus_sorted_from_bone_marrow_lof_mouse_gpl6887_gse44063	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.10533
GSE167474_2_v_3_naa40_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-QV44-2026-SM-2S1RD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45093
GTEX-XBED-2626-SM-4E3J5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49581
GSE195559_6_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
paracentral lobule, posterior part, left, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.06095
GTEX-R55D-0626-SM-3GAD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41044
MMS22L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25164
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TM31	CCLE Cell Line Gene CNV Profiles	1.0	1.37257
metoclopramide-3625	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GA-88-CF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.212788
WC-09-GD62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.2538
Folium-tuber vermis (VII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18473
PMC10350077-media-8.xlsx-PPM1D_tr_LPS_vs_Cont_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17624
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17994
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
LS_30min_LPS vs ctrl_RAW264.7_macrophage (Mouse) [20222745]	SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Drugs	1.0	null
Purkinje cell layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56828
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83T-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WOFM-1326-SM-3MJFR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57968
paroxetine-3904	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
aztreonam-5535	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A8S1-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE205070_2_v_5_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of PSPa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12276
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUW1-1726-SM-4BOOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.20573
POLR2A_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.043246
GTEX-WL46-2926-SM-3LK82	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917348
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04916
USF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1759
terete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.9527
GSE254517_3_v_0_irf7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QESD-2026-SM-447BI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889891
POTEF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66727
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
18757322-TableS1	GeneSigDB Published Gene Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.25951
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.954463
hsa-miR-137	TargetScan Predicted Conserved microRNA Targets	1.0	0.293524
Primary somatosensory area, trunk, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04554
meclozine-5607	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
posteroventral (inferior) parietal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0391
GTEX-T8EM-1326-SM-3DB7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98796
NIPBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70421
PMC4212256-mmc5.xlsx-FLI1_log2_results-MIR622_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
cinchocaine-1469	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XOTO-0526-SM-4B662	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.978338
GATA2	ChEA Transcription Factor Targets	1.0	null
STAT1-20625510-HELA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZH-0926-SM-48TBR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51969
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.976855
GSE246911,GSE246913_4_v_1_arid1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BC-54-ON71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.970971
GTEX-XOT4-0526-SM-4B66O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28939
FOXH1-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
inferior colliculus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.923886
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMAD4-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE239541_8_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12396377-jcb_202307079_tables1.xlsx-Fig_1C_i_-_iii_left-y_TFEB_KO_LLOMe_VS_WT_LLOMe_DOWN_TFEB	Rummagene Transcription Factor Associations 2026	1.0	null
MALME 3M	BioGPS Cell Line Gene Expression Profiles	1.0	0.858811
I3C	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.31
SW1990_PANCREAS	CCLE Cell Line Proteomics	1.0	4.18064
GSE197571_3_v_1_foxm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NANOG	ENCODE Transcription Factor Targets	1.0	null
ADH7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00441241
tropicamide-3619	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE79291_1_v_2_streptozotocin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QDT8-0526-SM-3NMD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.896563
GSE176008_0_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.8609
STAT1	ChEA Transcription Factor Targets	1.0	null
hsa-miR-3922-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.131849
GSE136894_2_v_3_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
G22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.08489
CRCGN016_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7353
POLR2A_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:A18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17052
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15156
hsa-miR-548t	TargetScan Predicted Conserved microRNA Targets	1.0	0.075559
ICC3	DepMap CRISPR Gene Dependency	1.0	2.12751
BRD-K14309706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65487
NUDHL1	CCLE Cell Line Gene Expression Profiles	1.0	2.02687
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1616
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76455
GSE196962_2_v_1_parg_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.828372
sulfanilamide-6810	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
kasugamycin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25603
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09358
PDCD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18869
BRD-K87205390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56283
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q734-0426-SM-48TZX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72578
TAF1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-8008-11A-01R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFON-2326-SM-3LK7M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.986802
BRD-K67131822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71678
Specific granule lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.052
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NBTGR	DeepCoverMOA Drug Mechanisms of Action	1.0	0.29
F-actin capping protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.874
GTEX-TML8-0526-SM-32QOQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.956154
Micronuclei, Chromosome-Defective	CTD Gene-Disease Associations	1.0	1.09892
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.835651
PMC5578490-pgen.1006879.s017.xlsx-Top_ETV1_downregulated_genes-Gene_Symbol_ETV1	Rummagene Transcription Factor Associations 2026	1.0	null
LS411N	DepMap CRISPR Gene Dependency	1.0	3.66759
SA1-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE128333_4_v_5_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE220914_1_v_0_zdhhc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SW982	DepMap CRISPR Gene Dependency	1.0	2.20828
mantle zone of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.81497
BRD-K91084609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14176
POLR2A_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE205540_2_v_3_phloridzin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S4P3-1626-SM-3K2AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78589
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	1.0	2.93711
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE180200,GSE180201_3_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
basolateral amygdaloid nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17707
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933568
GSE149903_4_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HOP-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.853637
Coronary heart disease	GWAS Catalog SNP-Phenotype Associations	1.0	0.042592
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01397
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
BRD-K74611044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15303
RELA	ENCODE Transcription Factor Targets	1.0	null
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.067116
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Interanterodorsal nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32435
CTCF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE236437_0_v_3_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SNMC-1426-SM-2XCFM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.05419
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.924876
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35788
hsa-miR-4505	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE217552_3_v_5_fisetin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.24609
Caudatenucleus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.873745
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52576
GSE179880_7_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE235945_1_v_0_pikfyve_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.14281
Lung squamous cell carcinoma_LUSC_TCGA-98-A53C-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COV504	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60785
caudal (posterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.63761
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4167-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K22185032	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54435
hsa-miR-4476	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1577
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.12569
BRD-K02987495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52601
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MF-65-HS14_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.229112
HCT-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
prochlorperazine-1215	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.976855
haloperidol-5563	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
paraventricular nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0015
CREB1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARID3A	ENCODE Transcription Factor Targets	1.0	null
GATA1-19941827-MEL-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC11474056-pnas.2404841121.sd01.xlsx-Supplemental_Table_8_Fig1G-H-Supplemental_Table_8_Transcriptomic_overlap_between_LPS_and_Sepsis_and_or_Tuberculosis_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE198165,GSE198166_7_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MITF	ChEA Transcription Factor Targets	1.0	null
decreased macrophage cell number	MGI Mouse Phenotype Associations 2023	1.0	null
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.26704
K2	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.43872
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42903
GSE152441,GSE152442_6_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-324-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
CD-05-PU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.765216
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-2392	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GSE88819_11_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-P4PQ-1026-SM-3NMCN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1467
OCUBM	DepMap CRISPR Gene Dependency	1.0	2.4129
GSE114883_0_v_4_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
FC-20-EQ58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.232206
WholeBlood	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.70206
RPMI-6666	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.44665
PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-NT_Fig1c-Gene_Symbol_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
dizocilpine-5746	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE215086_1_v_7_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
procainamide-2618	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
abnormality of the vasculature	GWASdb SNP-Phenotype Associations	1.0	0.111642
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRMT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89642
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05784
GSE130217_5_v_3_sesn2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.976855
STAT6	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K71537757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04021
hsa-miR-4283	TargetScan Predicted Conserved microRNA Targets	1.0	0.31417
GSE196699_7_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2786
BCL3	ENCODE Transcription Factor Targets	1.0	null
GSE167324_1_v_0_eif4e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K57516590	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51302
benfotiamine-6032	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
IPC-298	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.824031
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.52559
MLKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13787
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
WDR37	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00467403
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3QD-01A-32R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K63950697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28449
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10603
skeletal muscle	HPA Tissue Protein Expression Profiles	1.0	1.28518
BRD-K42506600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36689
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
motor nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.55435
propofol-5306	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAL1_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
flunixin-3411	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Declive (VI), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66209
CTCF_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
iocetamic acid-3361	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE150215_1_v_2_etl4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
proglumide-3972	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Prdm15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.0375
H3K9ac_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral hypothalamic area, tuberal region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.901099
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Agranular insular area, ventral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04762
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4637-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE255680_1_v_0_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dorsal thalamus_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02115
EBF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBP_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE135030_3_v_1_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_GM12875_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K19691332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.26931
GSE150669_2_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
LE-80-QM43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211701
BRD-K15931098	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05292
WDCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06074
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF_Q1_vs_Q4-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.49251
nimodipine-6480	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ketoprofen-2316	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
tropicamide-2309	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE114883_0_v_5_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cuneus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.51376
CEBPB	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RUNX1	ChEA Transcription Factor Targets	1.0	null
imidurea-5481	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H4K91ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Neutrophil degranulation	Reactome Pathways 2024	1.0	null
GSE168797_1_v_6_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.51363
coronary disease	GAD Gene-Disease Associations	1.0	null
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
BC-54-ON71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.397447
BRD-K68530167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27557
etamivan-2879	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PBX-27287812-CHIP-SEQ-EMBYONIC-LIMB-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE149943_2_v_3_cd8a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intermediate stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38685
amygdalohippocampal transition zone, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00946
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26275
piracetam-5462	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE201217_4_v_6_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
WC-16-IR43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.317815
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.8597
trimethoprim-7377	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE118617,GSE118619_0_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE101546_3_v_5_setdb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE206516,GSE206518_5_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52943
BRD-K98880643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10915
Triangular nucleus of septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14432
Paraventricular hypothalamic nucleus, magnocellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07152
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.28879
CRCGN015_HEPG2_48H:F04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.20479
mesalazine-5888	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K65315551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46699
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21687
Perturb_1579_KO_Dnttip1_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.3595
ZBTB7A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K05718365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30031
cytisine-5739	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ebselen-3458	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.5499
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AA-11-RO46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.334396
ED-05-LQ40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.313645
GSE195503_3_v_2_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5162-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA3_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.63286
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12518476-10067_2025_7574_MOESM8_ESM.xlsx-Sheet1-Up_regulated_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210101,GSE210114_0_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K71824916	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06098
GSE152441,GSE152442_6_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inner CP in (rostral) midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31819
GSE195559_0_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169205_0_v_6_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37354
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.940234
BRD-K69158240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87164
intermediate stratum of r10BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01877
GSE182179_2_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lobule II, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03442
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.892333
noscapine-7204	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
layer 1 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13635
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03461
hydrocotarnine-6827	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE101239_3_v_0_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H2BK120ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE154069_2_v_4_satb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4173-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-51-4080-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8984
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K46839342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46295
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K07534805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07002
GSE125862_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE58724_1_v_4_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.20492
CE-96-GH46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.77138
Perturb_8404_KD_Cebpb_SRP312780	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
POLR2A_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UTHO-0726-SM-3GAEN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02147
anterior tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54543
PMC4580625-pone.0138726.s006.xlsx-Immune_molecular_modules-NFKB1_mod_NFKB1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE178292_0_v_2_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
r9 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04272
GSE122101,GSE122103_0_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CF-87-AS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.431086
BRD-K67783817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53859
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ8I-1726-SM-4BOQB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56105
YA-78-MS95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.518395
HS578T	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.39125
prednisone-1478	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-30b	TargetScan Predicted Conserved microRNA Targets	1.0	0.140752
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
QA-07-KC40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.768778
ventral tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0693
Lung squamous cell carcinoma_LUSC_TCGA-77-8131-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.64054
Perturb_11868_OE_Ezh2_SRP059688	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.18413
GSE229978_4_v_7_morphine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K61711624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71932
REST_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-485-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
verapamil-161	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0011-R11A-SM-2HMJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59055
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0081
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	1.0	2.04839
Lung squamous cell carcinoma_LUSC_TCGA-56-8201-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A20697603_T8902_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE242367_1_v_0_dpp9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.82665
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Platelet distribution width	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.31549
HCT-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
BRD-K50894381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3563
SRF	ENCODE Transcription Factor Targets	1.0	null
paroxetine-3821	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H4K20me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE231829_0_v_1_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE239844_8_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
dequalinium chloride-5396	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K55478267	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19337
LS_10min_LPS vs ctrl_RAW264.7_macrophage (Mouse) [20222745]	SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Drugs	1.0	null
6-benzylaminopurine-3623	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7861-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
imatinib_homo sapiens_gpl96_gds3049	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SKBR3	DepMap CRISPR Gene Dependency	1.0	2.33914
posteroventral (inferior) parietal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.887618
FOXP2	ENCODE Transcription Factor Targets	1.0	null
BRD-K87213231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4907
SP2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TA-34-CK62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.29973
MAX	ENCODE Transcription Factor Targets	1.0	null
GTEX-POMQ-0526-SM-3GADD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83843
Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-11A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superior occipital gyrus, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.987923
PMC11096100-41588_2024_1714_MOESM3_ESM.xlsx-ST18-Unnamed_1_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
GSE58724_1_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BB-87-SF89_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.529524
Nucleus of the solitary tract, gelatinous part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3052
GSE135030_11_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE68156_3_v_4_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53517
PMC8047442-EMBJ-40-e105492-s003.xlsx-MR_plot_analysis-Gene_names_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
pralidoxime-6283	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20R-11A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H4K20me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1408
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.835651
NCIH146_LUNG	CCLE Cell Line Proteomics	1.0	2.19034
CRCGN016_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.6684
proglumide-2363	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:N17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5011
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27284
JAK2_knockout_79_GSE26188	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.46388
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.853637
GSE161055,GSE161056_1_v_0_hira_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A4AV-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.267418
GSE223008_7_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
inner SZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.934701
wt1_17420277_e11dot5_urogenital_ridge_lof_mouse_gpl1524_gds2747	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.051275
MECOM-23826213-KASUMI-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
LDL cholesterol	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.504576
BRD-K53447551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10989
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03959
HT-1376	GDSC Cell Line Gene Expression Profiles	-1.0	-1.51969
hsa-miR-542-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
BRD-K44684577	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39067
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.0105
CNOT1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN009_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.08851
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-SP3_SP3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142210_4_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
lateral septal nucleus, intermedio-intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18779
BRD-K21990363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11947
PMC10350077-media-8.xlsx-Controls_LPS_enriched_Down_KEGG-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.3228
nordihydroguaiaretic acid-1223	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE135030_8_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
OVTOKO	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55913
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65291
HT-3	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.08717
20124481-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
Flocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23011
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A62N-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JC-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RS5	CCLE Cell Line Gene Expression Profiles	1.0	1.36623
GTEX-U3ZH-0008-SM-4DXT2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936823
BRD-K56915252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72056
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE211128_9_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
terazosin-6092	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ChIP_STAT3_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K32759631	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01339
enilconazole-5538	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_cardiac fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5551-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MARK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01932
ketanserin-6649	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SF-0008-SM-3NM8T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07225
bone marrow	HPA Tissue Protein Expression Profiles	1.0	1.28518
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE232558_0_v_1_fbxl12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.34509
GTEX-WZTO-1326-SM-3NM8X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.890369
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
COLO-792	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.69775
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K18856772	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20287
IGR-37	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.73023
Flocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19841
ITM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31665
Coronary Disease	dbGAP Gene-Trait Associations	1.0	0.29992
GSE57871_1_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE103068_0_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hypertension	CTD Gene-Disease Associations	1.0	1.22758
BRD-K72866723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03272
POLR2A_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DCTN6	Pathway Commons Protein-Protein Interactions	1.0	null
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5412
EFR3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27551
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1105	CCLE Cell Line Gene CNV Profiles	1.0	1.68798
Primary visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33705
liver	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.825181
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
BRD-K11404512	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22135
GSE159148_0_v_1_sdc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.82985
clozapine-5589	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22486
alpha-estradiol-702	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE168797_1_v_5_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE172247,GSE172250_0_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
aciclovir-1960	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
butein-582	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN009_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.58245
Acute Myeloid Leukemia_LAML_TCGA-AB-2837-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Urinary bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.273
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CAL-27	GDSC Cell Line Gene Expression Profiles	-1.0	-1.90947
GATA4_INACTIVATION_GDS3663_519_mouse_Endothelial-derived cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CP-319743-7532	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
IRF1	ENCODE Transcription Factor Targets	1.0	null
CRCGN015_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.236
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLC/PRF/5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.966095
SW620_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	2.41387
phenazopyridine-6100	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TUHR4TKB_KIDNEY	CCLE Cell Line Proteomics	1.0	2.24183
GSE43041,GSE43044_0_v_1_ldb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K39419290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2803
CTCF_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IC-05-AW29_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.264196
S-propranolol-5444	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K81120201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3284
tretinoin-447	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PcPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64148
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.929639
PFKL_OE_GDS3353_76_human_B cells in blood	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-R55D-1426-SM-48FEN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10324
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23022
GSE256181_1_v_3_etv2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210101,GSE210114_0_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-711	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
CTCF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:L15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2342
NCIH1437	CCLE Cell Line Gene CNV Profiles	1.0	1.37989
azacyclonol-5398	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-940	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
MDA-MB-415	GDSC Cell Line Gene Expression Profiles	-1.0	-1.79936
idoxuridine-1899	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S95S-1426-SM-2XCDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28115
GSE129389_0_v_3_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE242199_9_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lobules IV-V, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4361
IZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.78916
TAF1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QXCU-1726-SM-2TC6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27965
GSE226584,GSE226589_1_v_0_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE226115,GSE226116_2_v_0_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RWS6-1126-SM-47JXC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14538
metyrapone-6447	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
trimethoprim-4701	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06272
macrophage apoptotic process	GO Biological Process Annotations 2025	1.0	null
TAF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE235682_3_v_0_rbl2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Asthma, allergic_Lung Tissue_GSE3184	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.40098
HCC1143	CCLE Cell Line Gene CNV Profiles	1.0	1.42238
BRD-K69671285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21648
GTEX-RU72-1326-SM-2TF6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.988968
CF-24-KQ98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.371477
loperamide-1533	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.46103
BRD-K42553302	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0492
GSE112962,GSE112963_2_v_1_ddx5_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U4B1-0726-SM-4DXUA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07788
GTEX-SJXC-0526-SM-2XCFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67438
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2625
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BACH1	ENCODE Transcription Factor Targets	1.0	null
lymphnode	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.32424
POLR2A_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FLT1_knockdown_111_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.09402
Brain Lower Grade Glioma_LGG_TCGA-HT-8106-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE178292_0_v_3_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
CYRIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23145
Lung adenocarcinoma_LUAD_TCGA-75-5122-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.03337
levothyroxine sodium-4150	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SIN3A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMAD2/3-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
paraventricular nucleus, cap part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05582
clozapine-2644	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K96970199	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58073
mephenesin-2304	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02511
Sarcoma_SARC_TCGA-DX-A3M2-01A-21R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-525-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49468
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8334
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.74645
PAXBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05935
isoxsuprine-1904	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-492	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
posteroventral (inferior) parietal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.50853
methotrexate-2041	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WQUQ-0006-SM-3MJF4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00376
Immune System	Reactome Pathways 2024	1.0	null
altizide-6829	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE179880_1_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K27372445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6246
GSE149903_5_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PD-70-VS77_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.491406
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6979-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE229978_4_v_2_morphine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
OSBPL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55428
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE143316_0_v_6_somatostatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
DU4475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12044
MRGBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17353
tremorine-3196	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
parvicellular interstitial nucleus of the posterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08054
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05118
BRD-K31521981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02474
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A5RI-11A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prestwick-559-2877	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K51757923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93791
GTEX-QV31-0126-SM-447BP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55528
BRD-K99545815_PF-562271_PC3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HT-3	GDSC Cell Line Gene Expression Profiles	-1.0	-1.72418
GSE88819_11_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K97805186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76555
MEF2A	JASPAR Predicted Transcription Factor Targets	1.0	null
Secondary motor area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06756
Rectum adenocarcinoma_READ_TCGA-DC-6156-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE190384,GSE190386_1_v_8_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
posterobasal nucleus, intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36084
GSE111385_0_v_1_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE196699_2_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-3658	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Vermal regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22978
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.28313
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K81642886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23659
GSE125219,GSE125221_4_v_8_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
FF-86-NH56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.767107
FCGRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29878
nicardipine-5397	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Malignant mesothelioma of pleura_Pleura_GSE2549	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.44659
BRD-K93295557	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03545
GSE159678_6_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE149903_6_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U412-0826-SM-3DB9K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888378
BRD-K70057550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42903
BRD-K83721789	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00634
TP53-23651856-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.8468
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30601
GSE239844_7_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC6977700-aging-12-102667-s006..xlsx-Sheet1-The_identified_941_dysregulated_LmiRM-CTs_in_MI_using_traditional_method_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.88731
KLF5-25053715-YYC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_7116_OE_Sirt5_SRP364867	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.81627
CRCGN015_MCF10A.TP53.M_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.49725
GTEX-XQ8I-0626-SM-4BOPT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.951268
GSE136627_3_v_1_hdac4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DPP3_OE_GDS2653_650_human_IMR-32 neuroblastoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
carcinine-3242	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC12079334-ADVS-12-2501734-s002.pdf-149-ENSG00000180357_ZNF609	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8625-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LY-294002-424	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE88819_0_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE140200_1_v_3_trim59_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.029009
GSE229973_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
TAF2-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE114690_1_v_0_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.64304
GSE168807_6_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
spleen	GTEx Tissue Gene Expression Profiles	1.0	1.87564
GTEX-XUZC-2126-SM-4BRW8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42151
osteoclasts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.32939
GSE180200,GSE180201_5_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.2756
GSE210682_0_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906584
GSE100316_7_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BD-A2L6-11A-21R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE113106_3_v_5_dnm2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178255_3_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12869_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HL-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.91373
GTEX-WRHK-1626-SM-3MJFH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38958
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.9578
CAKI1_KIDNEY	CCLE Cell Line Proteomics	1.0	2.31538
PMC11965130-DataSheet3.pdf-27-SETDB2_SETDB2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RU72-1426-SM-46MUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.943513
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8637-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sulfamethoxazole-7366	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE236502_2_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GABPA_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_16637_KO_Drd2m_SRP377988	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.75009
DBTRG-05MG	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.11475
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28616
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-TP53_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T2IS-2926-SM-32QPO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.984954
GSE225735_0_v_4_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
lung	HPA Tissue Protein Expression Profiles	1.0	1.28518
GSE205070_1_v_9_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ofloxacin-2302	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
JARID1B-DAIN-22020125-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GATA1_G1E-ER4_mm9_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.30126
AB-30-CR11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.245478
Cell periphery	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.555
drofenine-3455	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6829-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49068
PMC5771075-12896_2018_414_MOESM1_ESM.xlsx-MSC_all-Gene_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MC116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55126
hsa-miR-1909	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
TAL1_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS936T	CCLE Cell Line Gene Expression Profiles	1.0	2.51347
lymph node	HPA Tissue Protein Expression Profiles	1.0	0.731705
CRCGN015_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.74569
BRD-K02484256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16774
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.923144
Perturb_11576_KO_Zip8_SRP344283	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.24934
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.908015
Lung squamous cell carcinoma_LUSC_TCGA-90-6837-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE73562,GSE73563_1_v_2_preb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-2662-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAL1_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.853841
hsa-miR-24	TargetScan Predicted Conserved microRNA Targets	1.0	0.159923
GSE210476_2_v_0_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.31321
GTEX-OHPM-0326-SM-33HCA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07384
GSE111385_2_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K54212583	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0164
BRD-K03515786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65696
CTDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15524
BRD-K35049668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42329
globus pallidus, external segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.2475
GSE226249_0_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE201309_1_v_6_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
inflammatory cell apoptotic process	GO Biological Process Annotations 2025	1.0	null
pontine nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01239
dapsone-5498	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-QEL4-1326-SM-447AD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3262
POLR2A_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0826-SM-4B65O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19849
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.923144
BRD-K88495921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4931
GSE126127_0_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CHD1-19587682-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55G-2326-SM-2TC61	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.930566
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.98325
ventrolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01979
SPI1-23547873-NB4-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K88836117	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57193
hsa-miR-483-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
VMRCLCD	CCLE Cell Line Gene CNV Profiles	1.0	1.778
GSE192860_0_v_1_trifluoperazine_human	RummaGEO Drug Perturbation Signatures	1.0	null
timolol-5280	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE223008_9_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T5JC-2326-SM-32PMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828745
sulfamethoxypyridazine-3711	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
apramycin-4959	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
chloramphenicol-5466	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE211128_4_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.43559
GSE202434,GSE202438_13_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K24748087	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04506
hsa-miR-519a	TargetScan Predicted Conserved microRNA Targets	1.0	0.092495
COV644	CCLE Cell Line Gene Expression Profiles	-1.0	-1.74122
CRCGN016_MCF10A.TP53.M_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.54947
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8144425-41467_2021_22930_MOESM4_ESM.xlsx-Fig_5c_Post-Viremia-ATF5_ATF5	Rummagene Transcription Factor Associations 2026	1.0	null
valproic acid_mus musculus_gpl6885_gse35291	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K74568359	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86465
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.34625
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A1HT-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE88819_3_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Septofimbrial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44558
hydrocortisone-3284	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1500	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53973
17616640-TableS3	GeneSigDB Published Gene Signatures	1.0	null
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2486
GSE117042_1_v_3_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE201217_3_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
midbrain reticular formation	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.48641
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15535
CA3 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15594
GSE209577_0_v_1_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K76910883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24361
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.76668
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-8262-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AB-18-YN11_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.34658
BRD-K48813201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61626
prilocaine-2314	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SPI1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13128
GATA1-22383799-G1ME-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
EA-18-FP00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.27495
GSE154074_5_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SMARCB1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RNOR-0826-SM-2TF5C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917649
BRD-K98731550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05351
Inflammation	CTD Gene-Disease Associations	1.0	1.78473
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K14695950	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05903
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.17601
NANOG_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211931_1_v_3_ncoa4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.828296
Lung adenocarcinoma_LUAD_TCGA-44-2668-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01754
P300-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-W5X1-0006-SM-3GIJZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933268
GSE226249_5_v_6_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE235390_4_v_0_lurbinectedin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
tyloxapol-6452	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
pre-B acute lymphoblastic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.932
CCNT2	ENCODE Transcription Factor Targets	1.0	null
inner SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.50951
Prostate adenocarcinoma_PRAD_TCGA-EJ-7315-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.55695
CTCF_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fumagillin	DeepCoverMOA Drug Mechanisms of Action	1.0	0.3
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF3-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE173232_2_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
E2F4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE112860_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
interstitial nucleus of the posterior limb of the anterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02982
rofecoxib-463	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
haloperidol-1203	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SPI1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IGF1_OE_GDS3484_538_human_MCF-7	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
estradiol_homo sapiens_gpl571_gds4052	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
harpagoside-4981	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE225218_9_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE149903_0_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6977700-aging-12-102667-s004..xlsx-Stage1-The_identified_3126_dysregulated_LmiRM-CTs_in_stage_1_of_MI_1_day_of_MI_using_our_method_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
SIN3A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BE-27-RQ61_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.284295
ACTR1B	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K40221630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03611
GSE125157_1_v_0_piceatannol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-5303-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.7203
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M3-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SJSA-1	GDSC Cell Line Gene Expression Profiles	1.0	2.07115
SPI1_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.36474
GSE89018_6_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE152432_6_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM12869_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
methylbenzethonium chloride-3850	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
fludroxycortide-7378	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J9-A52C-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.11475
GSE130956_2_v_1_icaritin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	1.0	2.09229
ketoconazole-5685	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
chlorpromazine-1217	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SMAD3-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
liminal reticular formation of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39264
CRCGN008_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.40135
hsa-miR-4700-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
BRD-K28314528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60978
GSE165560_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8185471-mmc4.xlsx-D4-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_4_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
EGR1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE232631_0_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GNG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21578
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.55944
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883118
GSE151829,GSE151831_3_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.7953
aciclovir-1543	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE148695,GSE167284_2_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-NFK9-0626-SM-2HMIV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45551
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZQ-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFYB	ENCODE Transcription Factor Targets	1.0	null
gracile nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.827921
19218430-TableS3	GeneSigDB Published Gene Signatures	1.0	null
iopanoic acid-5448	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.40053
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FV-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
U0125-663	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cinoxacin-3463	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
intermediate stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0693
GSE160817_2_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
AA-58-FJ71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.311848
BRD-K51743001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43502
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9882
CTCF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC3804941-supp_jem.20122709_JEM_20122709_TableS1.xlsx-Suppl_Table_1C-1772_genes-Table_S1_C_1_772_significantly_overexpressed_genes_during_AR_when_combining_p-values_at_FDR_20_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OHPK-0326-SM-2HMJO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895655
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.349528
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mcf7	HPA Cell Line Gene Expression Profiles	-1.0	-0.9054
GSE167474_1_v_3_naa40_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OOBJ-0926-SM-48TDO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29489
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48123
mantle zone of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04192
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.20799
Primary somatosensory area, trunk, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51404
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09152
4-hydroxyphenazone-1915	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K84606053	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.09367
principal sensory nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.23285
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
U20S	BioGPS Cell Line Gene Expression Profiles	1.0	1.51092
acemetacin-7442	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.30654
FB-39-CW59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.212364
BRD-K87088675	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20502
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PLIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47392
GSE173873_2_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142210_9_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10757
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Penis_Foreskin_Melanocyte_Primary_Cells_skin03	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.967123
PMC9362915-pone.0272017.s003.xlsx-Day5_-0_7_Top-BBX_BBX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE173873_10_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE57871_1_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_MEL cell line_mm9_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE144838_2_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE206226_2_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
altretamine-5688	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K55916310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01338
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5085
oxybutynin-3168	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5K3-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7DV-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BA-88-HT15_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24823
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.34572
SMARCA4-20176728-TROPHOBLAST STEM CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ETS1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-MEL-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.847943
GSE173232_1_v_0_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBJ-1626-SM-2I3F7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.03953
GSE158458_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.974083
progesterone-4992	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PBX3	ENCODE Transcription Factor Targets	1.0	null
GTEX-QEG4-0008-SM-48TYZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15769
pirenzepine-7226	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE152441,GSE152442_0_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.905198
GSE261563_9_v_8_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Secretory granule lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.908
CRCGN015_MCF10A_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.8788
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7376-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ficolin-1-rich granule lumen	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE57871_5_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
liminal periaqueductal gray of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02585
GSE126463_6_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE126127_2_v_3_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Purkinje cell layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14406
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84599
GTEX-WL46-0626-SM-3LK7R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68428
BRD-K08558441	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4635
JVM2	CCLE Cell Line Gene Expression Profiles	1.0	2.11392
TAL1-20566737-PRIMARY FETAL LIVER ERYTHROID CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPK5-1626-SM-4JBHI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47784
apomorphine-1505	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Mucinous stomach adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.336
RAD21_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.1918
hydroxyzine-1941	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01536	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.918032
BRD-A12894472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07353
H3K79me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24206
STAT1-20625510-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
hacat	HPA Cell Line Gene Expression Profiles	-1.0	-0.824248
CE-18-AP15_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.21624
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05302
RecQ family helicase-topoisomerase III complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.149
CD1C-CD141- dendritic cell_Blood_Human	CellMarker Gene-Cell Type Associations	1.0	null
Zic3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.0768
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GC-04-UF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.429519
CRCGN016_MCF10A.TP53.M_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3512
PMC8190596-mmc2.xlsx-RUNX1_mut-RUNX1_mut_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
streptomycin-7194	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WFG7-2226-SM-3GIKP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02751
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11165
tetrahydroalstonine-2748	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DD-74-PJ26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.413728
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38477
GSE140651,GSE140653_2_v_7_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ketoconazole-2640	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-QESD-0626-SM-2I5G4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967321
GSE119345_2_v_4_bexarotene_human	RummaGEO Drug Perturbation Signatures	1.0	null
SK-MEL-28	GDSC Cell Line Gene Expression Profiles	1.0	1.48862
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1651	CCLE Cell Line Gene CNV Profiles	1.0	2.04323
Platelet count	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.922185
GSE166315_5_v_4_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Paraflocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21474
BRME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14673
GTEX-RTLS-1326-SM-46MUN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26285
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40548
Lung squamous cell carcinoma_LUSC_TCGA-34-7107-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UO31	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.891642
FE-56-PV35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.597238
BRD-K03730976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43963
ventral tegmental area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17495
Olig2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.8727
GTEX-PWCY-0008-SM-48TE9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834589
azaperone-7231	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE218356_1_v_0_cited1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
promazine-6028	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HUT102	CCLE Cell Line Gene Expression Profiles	1.0	1.47519
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE226770_1_v_6_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DDB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00168
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6758
CTCF_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_3H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1429
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.824416
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0524
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12874_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KC-A4BR-01A-32R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE128730_4_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AC-47-YZ27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.379984
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-SOX4_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
nitrofurantoin-2341	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
mephenesin-7374	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QCQG-0426-SM-48U29	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842148
posteroventral (inferior) parietal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23788
CTCF_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S341-1826-SM-3K2AB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34227
Anteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82363
CTCF_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SF-1626-SM-3K2AY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.912181
H3K27me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
mercaptopurine-667	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10493
CORL279	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53655
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-D_ATF4-def_vs_HCT116_Tg2-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.911826
WT1-25993318-PODOCYTE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6147-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RELA_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MO-0008-SM-4DM6T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14798
CRCGN015_MCF10A.WT.HP_24H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.78173
SUSA	DepMap CRISPR Gene Dependency	1.0	2.23231
BRD-K75775113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31188
LIAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48806
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AI-0426-SM-48U13	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.931821
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YR-11A-13R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE169152_5_v_4_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
clotrimazole-5726	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Anemia	CTD Gene-Disease Associations	1.0	1.01549
BRD-K17070436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22347
CSTB_KO_GSE47516_18_mouse_brain (P7 cerebellum, P30 cerebellum, cerebellar granule cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K86995890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68595
Rectum adenocarcinoma_READ_TCGA-AF-2687-01A-02R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Flocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16781
GSE155567_2_v_0_cd33_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A69110666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35975
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	1.0	2.32385
CHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
oseltamivir-phosphate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12864
CRCGN015_MCF10A.TP53.M_24H:E16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.90585
PMC6718408-41467_2019_11884_MOESM6_ESM.xlsx-TAD_genes_ST-EPN-RELA-Unnamed_4_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K70652938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33731
KARPAS-620	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TA-34-CK62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.730266
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35516
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NG-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM21A	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN011_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5205
GSE173201_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
periventricular stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22484
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.02054
CC-04-WK34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.241443
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.887444
GSE149124,GSE149128_3_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4300	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
HCC1419	GDSC Cell Line Gene Expression Profiles	-1.0	-2.00903
CE-96-GH46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.43299
primary visual cortex (striate cortex, area V1/17)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.828035
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4328
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.921385
KD	DepMap CRISPR Gene Dependency	1.0	2.14582
ATP5MF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56237
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE131649_6_v_10_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.18562
A-Vietnam-1203-2004(H5N1)_7Hour_None_GSE43204	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.10814
TA-20-FO62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.241496
MITF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6378
GTEX-X4EO-0526-SM-3P5Z3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54365
A1207	CCLE Cell Line Gene CNV Profiles	1.0	1.34502
VZ in midcingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.49836
BRD-K46942548	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09747
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE57871_8_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K90359063	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40455
GSE149903_3_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
isoetarine-3451	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE166315_1_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.864709
MAZ_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tetracaine-2888	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6016-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K46149271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31825
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-POYW-0526-SM-2XCEY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0315
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE128634,GSE128636_4_v_5_foxo1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-WWYW-0526-SM-3NB2W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.906838
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14762
phenelzine-2319	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
picotamide-2070	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_GM18526_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
GSE212330_1_v_0_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE162276_2_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-YB-A89D-11A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_4_FDC-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02201
ZMAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22907
hsa-miR-206	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
PMC12808183-41598_2025_31780_MOESM7_ESM.pdf-4-CREB5_CREB5	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6498-01A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
papaverine-2747	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U9-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.TP53.M_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.61671
COMMD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90768
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
dimethadione-5668	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE113106_3_v_4_dnm2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100448_TCx_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.80225
UBTF_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCC9	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32732
BRD-K74918080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69861
BRD-K17956418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63866
GSE225735_1_v_4_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSK3A_knockdown_207_GDS4305	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.11072
DD-43-WW40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.281138
GTEX-Q2AI-0526-SM-2I3EJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941272
GSE127970_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.2647
TFAP2A	JASPAR Predicted Transcription Factor Targets	1.0	null
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF_D1_vs_D10-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE101239_5_v_0_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
JD-44-KF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.995685
MYB	ChEA Transcription Factor Targets	1.0	null
BRD-K78828094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03174
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17278
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE100102_0_v_3_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OIZG-1326-SM-2HMIQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4667
GTEX-SIU7-0426-SM-2XCDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895164
SP2_02_42	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.58888
BRD-K37527074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16851
CRCGN017_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.74115
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934365
gossypol-4762	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CCK-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
17906199-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
Lobules IV-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4423
GTEX-NL3H-0011-R3a-SM-2I3GL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827307
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EE-03-SG02_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.704312
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ6-0726-SM-3P619	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30834
GSE235390_4_v_2_lurbinectedin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23175
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-MEL-2	GDSC Cell Line Gene Expression Profiles	1.0	2.31228
Bed nuclei of the stria terminalis, anterior division, anterolateral area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24617
HS834T	CCLE Cell Line Gene Expression Profiles	1.0	1.37819
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.905081
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146546,GSE146807_0_v_1_igf2bp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CORL47_LUNG	CCLE Cell Line Proteomics	1.0	4.53586
GSE153189_1_v_0_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
parasolitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.59691
GFI1_KO_GDS4204_147_mouse_HSC	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
AA-22-UI44_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.262996
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-519d	TargetScan Predicted Conserved microRNA Targets	1.0	0.175726
Thymus-macrophage	Tabula Sapiens Gene-Cell Associations	1.0	0.692027
Lung adenocarcinoma_LUAD_TCGA-55-7728-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-QQ-A5V2-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5671-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BC-54-ON71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.349867
CL-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02387
Perturb_12889_KO_Chaf1b_SRP161931	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GSE173394_1_v_0_nfatc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8113
GSE122215,GSE122217_0_v_1_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GATA1_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25575
nucleus sagulum, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09857
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61546
parthenolide-5105	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
superficial stratum of isBI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22484
Brain Lower Grade Glioma_LGG_TCGA-DU-7006-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_13293_KO_Hdac3_SRP361157	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.5279
PMC9010637-mmc6.xlsx-5D-Figure_5D_Gene_Expression_Zhou_et_al_Application_of_SP3-Rox_to_identify_redox_changes_during_T_cell_maturation_SP3	Rummagene Transcription Factor Associations 2026	1.0	null
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03861
CTCF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V955-2426-SM-3GAEF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01225
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SG in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10959
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA1-19941827-MEL-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
SETDB1-19884257-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GSE144120_3_v_1_plcg2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE180185_9_v_8_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
yohimbine-2755	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
lysergol-4966	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.41963
GTEX-X4EO-0926-SM-3P5Z2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87598
JIYOYE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11012
hsa-miR-106a	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
U87	BioGPS Cell Line Gene Expression Profiles	1.0	0.861282
NCI-H2126	GDSC Cell Line Gene Expression Profiles	-1.0	-2.3577
GSE164874_5_v_0_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.832041
A549	DepMap CRISPR Gene Dependency	1.0	4.64701
minaprine-1468	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE122067_3_v_1_mtch2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE111061_1_v_0_tofacitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
(-)-atenolol-6444	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE198165,GSE198166_6_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH1573	DepMap CRISPR Gene Dependency	1.0	2.99478
BRD-K16044155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67307
PMC4390530-NIHMS667786-supplement-1.xlsx-Sheet1-Supplementary_Table_2_Genes_closest_to_AR_induced_ASH2L_peaks_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A2I4-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
prepontine hindbrain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09271
testosterone-2649	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K18253469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21591
ficolin-1-rich granule lumen	GO Cellular Component Annotations 2025	1.0	null
RAD21_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.5731
Hypertrophy	CTD Gene-Disease Associations	1.0	1.4098
SMRT-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.44091
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02257
superior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1548
BRD-K17705111	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12831
DC-51-WE27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.406387
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NELFE	ENCODE Transcription Factor Targets	1.0	null
GTEX-SNOS-0926-SM-4DM7A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873609
Lung squamous cell carcinoma_LUSC_TCGA-43-6771-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pyrantel-5513	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE124410_2_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KIAA0196	Pathway Commons Protein-Protein Interactions	1.0	null
GSE236502_1_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K33016067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.228
PMC7293310-41467_2020_16179_MOESM8_ESM.xlsx-Table_S9_GATA1_WT24h_vs_SET24-Unnamed_12_GATA1	Rummagene Transcription Factor Associations 2026	1.0	null
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46709
CRCGN014_HEPG2_24H:M15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.91347
KDM5A	ENCODE Transcription Factor Targets	1.0	null
mantle zone of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4816
496100390_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.02291
EEF1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	9.0061
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23922
GTEX-XUW1-0005-SM-4BOQ7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23944
CD71+_EarlyErythroid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.09304
dizocilpine-2232	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.995021
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K18316646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24213
BRD-K98490050_AMSACRINE_VCAP_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
APOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03975
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1IA-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nordihydroguaiaretic acid-4447	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12874_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23337
PMC3470785-NIHMS377161-supplement-3.pdf-629-ZNF696_ZNF696	Rummagene Transcription Factor Associations 2026	1.0	null
GSE255432_6_v_2_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
sulfamethoxazole-2296	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
stratum oriens of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01629
GSE114232_8_v_6_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
trimetazidine-5479	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE88819_0_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2973-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NME1-NME2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00495093
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09217
Left middle cerebral artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.195
STAT5A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-2626-SM-32QPP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40817
benzydamine-3169	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
eldeline-3831	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K82852523	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60281
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.92273
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63011
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4509
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-D_ATF4-def_vs_HCT116_Tg2-Supplementary_Table_2D_Contrast_ATF4-def_Tg_2h_vs_HCT116Tg_2h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WL46-2826-SM-3LK81	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17269
RUNX2	ChEA Transcription Factor Targets	1.0	null
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
etofenamate-4108	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-P4PQ-1626-SM-2HMKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06657
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Penis_Foreskin_Melanocyte_Primary_Cells_skin01	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.13517
hsa-miR-873	TargetScan Predicted Conserved microRNA Targets	1.0	0.123298
GSE132313_1_v_0_fosl2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ficolin-1-rich granule lumen	GO Cellular Component Annotations 2023	1.0	null
clozapine-6988	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
pridinol-7214	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
5194442-6599	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BD-18-MM33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.203057
CTCF_GM12875_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
GSE174701_5_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
PMC6332659__F3	PFOCR Pathway Figure Associations 2023	1.0	null
Neural crest-derived stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.73
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE136238_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE184892_4_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
ALEXANDERCELLS	CCLE Cell Line Gene CNV Profiles	1.0	1.35702
GSE158815_1_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WZTO-0826-SM-3NM8Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45745
GSE100316_3_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE239541_5_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.9632
TAL1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZN-0226-SM-3DB8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20054
GSE142019,GSE142021_1_v_3_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.61242
p2 portion of the parabrachial pigmented nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6952
BRD-K44341877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08094
hsa-miR-524-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE119345_2_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE131425_2_v_3_arg2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.96782
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.8181
TCF7L2_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CB-16-SY72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.222422
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.29593
CA-75-HA22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.51001
GSE165682_2_v_1_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE174701_5_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6744561-41467_2019_12125_MOESM7_ESM.xlsx-Normal_309_TCF7_rep1_sorted_pea-Gene_Name_TCF7	Rummagene Transcription Factor Associations 2026	1.0	null
globus pallidus, internal segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05184
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892104
BRD-K38917645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22701
GSE193999,GSE194000_3_v_2_atf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.6434
hsa-miR-4484	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
BRD-K29662589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65893
orbital frontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23697
GSE221356_1_v_0_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
copper sulfate-459	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-75-6205-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K04635516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24379
CAMTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38463
nitrendipine-5405	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
CTCF_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
picrotoxinin-4260	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
STOCK1N-35215-6422	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN012_HEPG2_24H:J19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.40778
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968979
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.64127
H3K4ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC9996951-40659_2023_417_MOESM3_ESM.xlsx-Osteo_vs_MSC_Array2_hypo_er_txt-Upstream_NAME_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE201401_2_v_0_fgfr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TML8-1826-SM-32QOR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40134
PD-70-VS77_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.738756
GTEX-N7MS-0426-SM-2YUN6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860612
GSE201361_0_v_1_mpst_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46955
GSE114992,GSE114993_9_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RITA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08882
GSE188458_2_v_4_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A50774520_-666_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
clofazimine-3239	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.92748
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5026
CRCGN015_HEPG2_48H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.51982
BRD-K32475622	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49392
GSE173873_8_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.840119
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23976
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85124
CRCGN010_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03031
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.98862
GSE146074_10_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RAD21_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE88819_5_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FLI1	ChEA Transcription Factor Targets	1.0	null
BRD-K17602350	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14478
GSE160001,GSE160670_0_v_2_lapatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE240896,GSE240899_10_v_4_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
eGFP-GATA2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.4016
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S32W-0326-SM-2XCBI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864423
ZBED1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2961
spectinomycin-3327	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE206502_2_v_1_igf2bp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Primary somatosensory area, barrel field, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00485
SUDHL8	DepMap CRISPR Gene Dependency	1.0	2.27692
vinpocetine-5859	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2981
CAPZA1	Pathway Commons Protein-Protein Interactions	1.0	null
diphemanil metilsulfate-1912	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.31966
Mesothelioma_MESO_TCGA-LK-A4O4-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
aminophylline-3374	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE148657_2_v_1_cd44_human	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6222-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLAUR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29666
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26396
GTEX-WFON-0126-SM-4LVM9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10952
BRD-K43023353	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18842
REST_PFSK-1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26396
clopamide-6301	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Superior colliculus, motor related, intermediate gray layer, sublayer c	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76184
internal granular layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25431
BRD-K87438596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02122
SW1463	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40751
spironolactone-2226	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE241036_4_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
naloxone-1506	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
amylocaine-1491	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.72605
Perturb_8612_KO_miR1792_SRP076942	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.61092
cinchonidine-5833	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07344
HT-144	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.981921
GTEX-QMR6-0008-SM-447AV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01366
NDUFB9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00422999
GSE174498,GSE174500_5_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Splenomegaly	CTD Gene-Disease Associations	1.0	1.01966
hsa-miR-17	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
GSE152441,GSE152442_7_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
RPMI8226	CCLE Cell Line Gene CNV Profiles	1.0	1.44853
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE234155_7_v_1_nfix_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_9514_KO_Zcchc8_SRP187429	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.59657
GSE137914_4_v_3_tet3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2813-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPK-1626-SM-2YUN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.99123
GTEX-S4Z8-0526-SM-4AD4T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.996589
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.966516
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A3F2-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE134693_0_v_1_msr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
periventricular stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0822
GSE126463_1_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVUS-0008-SM-447AY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02116
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.57856
NCIH209	CCLE Cell Line Gene Expression Profiles	-1.0	-1.79295
imipramine-5440	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
periventricular stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39023
intermediate stratum of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.73593
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE158182_5_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
nicardipine-6297	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70J-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149903_5_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U3ZG-0326-SM-47JXN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11847
GSE242367_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE62843,GSE64371_4_v_3_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10319804-41467_2023_38747_MOESM9_ESM.xlsx-KHSRP_KD_genes_down-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE215086_0_v_1_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XUW1-0826-SM-4BOP6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24995
ZBTB7A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRK-1826-SM-2HMJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69342
GSE89767_1_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HuP-T3	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.97823
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18014
etynodiol-6479	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC7927886-2019_239970_BOUSSAID_SUPPL_TABS2.xlsx-GATA1_targets_-_genesets-Unnamed_1_GATA1	Rummagene Transcription Factor Associations 2026	1.0	null
Innate Immune System	Reactome Pathways 2024	1.0	null
r1 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38863
Prestwick-689-6076	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CCRF-SB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.85017
GSE152441,GSE152442_6_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_11743_KD_Nsd2_SRP312884	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.70047
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAL1-20566737-PRIMARY-FETAL-LIVER-ERYTHROID-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
metanephrine-1933	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43U-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K79me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neural Tube Defects	CTD Gene-Disease Associations	1.0	1.07093
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16722
mantle zone of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38202
GSE166944_3_v_2_eif4b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE127970_2_v_3_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
periventricular stratum of JcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46996
BRD-K05462252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35163
GSE119564_1_v_3_zfp217_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GABPA_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K46994278	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26915
Perturb_11955_KD_Phf23_SRP248452	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.04474
plasma membrane	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Nucleus of the posterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07567
GTEX-QCQG-0226-SM-48U28	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35857
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3119
GSE158197_6_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CAL-120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29858
EC-62-OE64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.659652
carbarsone-3991	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Parkin_OE_GDS4476_55_human_U87MG	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.84721
GSE213588_9_v_7_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.12655
BICR22_UPPER_AERODIGESTIVE_TRACT	CCLE Cell Line Proteomics	1.0	2.2654
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11165
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BT-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sulfadiazine-5523	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3944-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.956782
JcPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.471
BRD-K62351887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75918
TE4	CCLE Cell Line Gene CNV Profiles	1.0	1.3933
Prostate adenocarcinoma_PRAD_TCGA-G9-6347-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
propranolol_mus musculus_gpl6885_gse42534	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06563
GTEX-XPVG-2526-SM-4B66D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39662
CRCGN015_HEPG2_48H:I06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.36392
IC-76-JU42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.540406
amygdaloid complex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19607
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HW-A5KM-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
zoxazolamine-5390	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fat_8b	HPA Tissue Sample Gene Expression Profiles	1.0	0.843299
C2BBE1	DepMap CRISPR Gene Dependency	1.0	2.40953
GSE199899_4_v_2_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
diethylcarbamazine-5485	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
co-dergocrine mesilate-2793	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7786-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FE-64-KC49_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.252937
Stereocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.897
CRCGN016_MCF10A.WT.HP_24H:A22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.61986
buspirone-2637	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
thioperamide-5270	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SP in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33047
riluzole-3666	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
sulpiride-1467	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-O5YT-1026-SM-3MJGF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848616
GSE254517_1_v_0_irf7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BCB000040-7488	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
tolazoline-1500	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Sarcoma_SARC_TCGA-PC-A5DN-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SNMC-0008-SM-4DM5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03834
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34191
CTCF_GM12868_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE154074_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0476
Brain Lower Grade Glioma_LGG_TCGA-DB-A75P-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
furazolidone-3358	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN015_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.90184
AE-39-DG66_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.251631
BRD-K26188625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66113
GSE153137,GSE153140_2_v_0_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.902472
PMC7293310-41467_2020_16179_MOESM8_ESM.xlsx-Table_S9_GATA1_WT24h_vs_SET24-Unnamed_10_GATA1	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
methotrexate-1957	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CHD1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YV-2026-SM-2D7VS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.943446
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.66764
spectinomycin-4773	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_GM12864_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86548
SPI1-23547873-NB4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.92273
Mpp10 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.518
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KM-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K64770897	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46678
biperiden-5279	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K79me2_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ELK1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_13025_KO_REL_SRP268648	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.85389
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FAM21C	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K98020844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32056
CDK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65946
METTL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03467
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.294
SP2	ENCODE Transcription Factor Targets	1.0	null
DB-21-FY75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.368476
NCI-H810	GDSC Cell Line Gene Expression Profiles	-1.0	-1.97152
GSE196117_1_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9541747-AGE-53-680-s003.xlsx-TableS6-Table_S6_Genes_with_missense_mutations_in_Yaroslavl_cattle_MAF_0_1_and_FST_0_4_in_the_1000_Bull_Genomes_Run_9_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE229914_1_v_3_keap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K09819684	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27244
tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13689
GTEX-R55G-0226-SM-48FEI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11668
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.44842
H2BK12ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MHC class I peptide loading complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.757
HARS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00313032
BRD-K79048835	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40573
QGP1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.04474
GTEX-PW2O-0526-SM-2I3DX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843138
GSE189834,GSE189836_1_v_0_brd4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE125211_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_MEL cell line_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UF-27-HS98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.583883
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.34459
NR2C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2653
Wt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	67.5474
gemfibrozil-2277	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DA-35-DU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.221756
dorsal motor nucleus of the vagus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.30288
hsa-miR-3918	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
intracellular	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Leukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MEIS1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K13761649	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5061
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE167886_3_v_0_chd7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UBTF	ENCODE Transcription Factor Targets	1.0	null
intracellular organelle lumen	GO Cellular Component Annotations 2023	1.0	null
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
striatum_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23229
layer V of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02976
SPI1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QV44-0926-SM-2S1RH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930081
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE225656_2_v_1_tsc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.14539
CD105+_Endothelial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.09408
CTCF_GM12872_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Spleen-endothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	0.821412
GSE118816_0_v_3_myo1c_human	RummaGEO Gene Perturbation Signatures	-1.0	null
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K27335290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13459
remoxipride-5443	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE111385_0_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K28029070	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47767
BRD-K13697129	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29372
ETS1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pancreas	GTEx Tissue Gene Expression Profiles	-1.0	-1.06081
dorsal preisthmic part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.94532
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
QA-07-KC40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.213446
iopamidol-7189	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KM12	GDSC Cell Line Gene Expression Profiles	-1.0	-2.21534
TP53-23651856-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE152734,GSE152735_1_v_0_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NB10	DepMap CRISPR Gene Dependency	1.0	5.48107
NCIH1355	CCLE Cell Line Gene Expression Profiles	-1.0	-1.65403
GSE225647_1_v_3_srsf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
central gray substance of midbrain, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.831067
GSE179693,GSE179694_4_v_2_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.731
GSE101537_1_v_3_neurog3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4806
GSE211128_4_v_1_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
parabigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.96816
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE160817_2_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7245-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chlorhexidine-6302	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
17234769-TableS2b	GeneSigDB Published Gene Signatures	1.0	null
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
monastrol-668	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-R53T-0326-SM-48FEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04809
TCF7L2_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02144
GSE120612_6_v_3_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SETDB1	ChEA Transcription Factor Targets	1.0	null
PMC5095001-oncotarget-07-36293-s002.xlsx-Table_S2-Table_S2_MYCN-correlated_genes_and_their_correlations_with_other_transcription_factors_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
GSE237040_6_v_5_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TMMY-1326-SM-4DXU9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13491
acemetacin-5460	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5Q5-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PX3G-0926-SM-48U12	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50211
intermediate stratum of CoPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17175
EE-98-PF86_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.279971
glibenclamide-5849	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
90S preribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.221
CRCGN017_MCF10A.TP53.M_24H:J01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4609
isthmic alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1047
Sarcoma_SARC_TCGA-DX-A8BZ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
metolazone-1514	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.52351
GTEX-QDVN-0526-SM-48TZ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20144
GSE169713,GSE169715_1_v_2_tert_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
MCF10DCIS.COM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.971889
GTEX-PWOO-0008-SM-48TDU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27706
496100323_FWM_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.62856
GSE122101,GSE122103_3_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
membrane	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE185944_2_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-5248-01A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
p3 portion of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03214
iproniazid-2125	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
REST_Panc1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06272
CRCGN013_HEPG2_24H:N13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.164
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.41954
BRD-K79318959	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01167
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202744_1_v_3_toyocamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-PX3G-1626-SM-2S1PT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13135
HNMPA-(AM)3-583	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE242199_2_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE178714_5_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58138
hsa-miR-4495	TargetScan Predicted Conserved microRNA Targets	1.0	0.088999
GSE147959,GSE147960_5_v_3_stat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CREB1	ENCODE Transcription Factor Targets	1.0	null
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52752
BRD-K37047627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30274
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07091
hsa-miR-1246	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
CRCGN010_HEPG2_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9725
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03129
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.916528
IC-05-AW29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.23271
Intracellular vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
L-methionine sulfoximine-2831	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K45723655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77617
Poisoning	CTD Gene-Disease Associations	1.0	1.64101
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7118
hsa-miR-650	TargetScan Predicted Conserved microRNA Targets	1.0	0.056784
Perturb_10895_KO_Jnk2_SRP038635	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.78577
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.8943
CRCGN015_MCF10A.TP53.M_24H:M08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1742
PMC6451017-41598_2019_42107_MOESM11_ESM.xlsx-all_MYCN_as_effector_lincRNAs-mRNA_genes_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0524
GSE203655_0_v_1_stat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_6_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6132-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE103068_5_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE193993_1_v_6_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GF-35-IT27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.293038
CTCF_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-L4-A4E6-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE96641_1_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K79me2_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE207787_1_v_4_pdha1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE226249_0_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.824552
PDHK1	Kinase Library Serine Threonine Kinome Atlas	1.0	null
periventricular stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64148
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.70129
GSE160817_3_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-30e	TargetScan Predicted Conserved microRNA Targets	1.0	0.111118
BRD-K57155690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0699
NCIH1963	CCLE Cell Line Gene Expression Profiles	-1.0	-2.22811
GSE148695,GSE167281_2_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202744_1_v_0_toyocamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
REST_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PP-1026-SM-3NM9O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1765
HDAC2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE211177,GSE211178_9_v_3_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RUNX1-22412390-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6778-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE100102_0_v_5_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VN-A88I-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE152441,GSE152442_1_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K46562329	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67403
GTEX-XPT6-2026-SM-4B64V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37219
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A69E-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K53146097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34254
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17095
GSE229973_3_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
DC-51-WE27_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.251467
YY1	ENCODE Transcription Factor Targets	1.0	null
napelline-6084	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE235550_1_v_0_hspa9_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_4321_KD_Cck_SRP220728	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.3736
raloxifene-3480	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE182680,GSE182683_7_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K93675803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93783
MYB-21317192-ERMYB-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
trifluoperazine-5584	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE217132_0_v_1_pfkfb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
adrenal gland	HPA Tissue Protein Expression Profiles	1.0	1.28518
CRCGN017_MCF10A.WT.HP_24H:G11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.279
doxorubicin_homo sapiens_gpl570_gse46493	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-PLZ6-0126-SM-48TC6	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00784
SK-MEL-2	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.24802
RUNX1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE120415,GSE120447_0_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE63048_11_v_5_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.16295
CREB1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55416
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K67478255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45531
Simple lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7149
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ELK3_ELK3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE196699_7_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.055
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hela	HPA Cell Line Gene Expression Profiles	-1.0	-1.10026
Ikzf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.0372
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE180200,GSE180201_3_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2981-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EJM	DepMap CRISPR Gene Dependency	1.0	2.26515
BRD-K98264372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01644
CRCGN017_MCF10A.TP53.M_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.7653
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07768
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.55729
striatum_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.47964
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
ME-31-RM40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.66772
AA-22-UI44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.423346
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3555
ketorolac-7286	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1628
mediodorsal nucleus of thalamus_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.894108
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-106b	TargetScan Predicted Conserved microRNA Targets	1.0	0.293524
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.797203
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03741
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3M9-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HC-74-HM63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.329407
BRD-K13071687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.17312
POLR2A_GM10847_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.992446
layer III of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.888229
PMC6977700-aging-12-102667-s004..xlsx-Stage4-The_identified_749_dysregulated_LmiRM-CTs_in_stage_4_of_MI_6_months_after_MI_using_our_method_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-4625-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-486-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
GSE239844_4_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02992
GSE211226_1_v_2_sirpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE110178_4_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WYJK-0005-SM-3NMA1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880897
GSE228413_0_v_3_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3TU-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K78816149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00709
AE-42-HT01_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.262804
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5163-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r2 part of median raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03136
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.77576
T3M3	DepMap CRISPR Gene Dependency	1.0	2.46205
GSE143512,GSE143513_0_v_1_nr4a3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135030_11_v_1_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.30336
CRCGN009_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15971
mantle zone of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64952
HAO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00614322
SYNCRIP_OE_GDS3186_84_mouse_wild type 129 mouse retina	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Perturb_15646_KO_Tet2_SRP255385	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Ebf2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.6508
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE148200_3_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
DC-47-KV62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.358033
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2267
STAT3	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE232223_1_v_0_letmd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
superficial stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14434
OPM2	DepMap CRISPR Gene Dependency	1.0	4.43272
RCH-ACV	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.92092
GSE155305_2_v_1_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE225684_0_v_2_tfap4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RD-90-OY66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215244
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.35433
loxapine-1516	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
propylthiouracil-2837	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE130715_1_v_0_budesonide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE88819_7_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H2BK120ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
U937	CCLE Cell Line Gene CNV Profiles	1.0	1.66805
GSE205070_1_v_5_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61921
CRCGN017_MCF10A.WT.HP_24H:M04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.11481
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35965
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149903_4_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K37454185	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52202
GSE232714_0_v_1_raver1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE207282_1_v_0_polydatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE119978,GSE180930_0_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
methyldopate-4986	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC11073998-41375_2024_2235_MOESM9_ESM.xlsx-THP1_phosphoproteome-Unnamed_2_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
TERT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12055
procainamide-4602	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
COLO800	DepMap CRISPR Gene Dependency	1.0	3.72668
GSE108495_1_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE111247_0_v_13_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09217
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.905081
BRD-K60430111	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55761
BRD-K72842159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19898
YD-49-HM53_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.339586
H3K9ac_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8563-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1770	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2A_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29691
BRD-K77518191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7842
Lung adenocarcinoma_LUAD_TCGA-69-8453-01A-12R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.94521
Lung squamous cell carcinoma_LUSC_TCGA-22-5482-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE115363_1_v_5_esrrb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary motor cortex (area M1, area 4)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3422
hsa-miR-214	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GTEX-U3ZH-1926-SM-4DXTR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.878576
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3376-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17135
medial geniculate complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.41113
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19S-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Familial combined hyperlipidaemia_lymphoblast_GSE1010	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.90299
CHD1	ChEA Transcription Factor Targets	1.0	null
hsa-miR-4695-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
UPF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05347
adrenosterone-6486	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2AphosphoS5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nephritis	CTD Gene-Disease Associations	1.0	1.04611
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7882-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K66675422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43207
CRCGN015_MCF10A.WT.HP_24H:C04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3549
tranylcypromine-7293	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
paracetamol-3364	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE193258,GSE193259_9_v_15_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF384	ENCODE Transcription Factor Targets	1.0	null
Periventricular hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82287
GSE213588_9_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary motor-sensory cortex (samples)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.932516
CRCGN015_MCF10A_48H:A07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1653
ZBTB7A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SN8G-0008-SM-4DM4X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921955
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.20613
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Peripheral_Blood_Mononuclear_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.07492
HS 895.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.34207
diphemanil metilsulfate-1494	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HINFP	JASPAR Predicted Transcription Factor Targets	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2838-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.957711
CLPP_KO_GDS4791_376_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CRCGN017_MCF10A.WT.HP_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.58155
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NT5C3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57363
CA2 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.13856
scopoletin-6510	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Preribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.017
GTEX-S4UY-0526-SM-3K2AN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36792
GSE180200,GSE180201_3_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H209	COSMIC Cell Line Gene Mutation Profiles	1.0	null
orbital frontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.33724
GTEX-REY6-0826-SM-2TF4S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18496
GSE148321,GSE169423_2_v_1_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RHPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14983
CLPP_KO_GDS4791_107_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CA-68-KG29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.517268
AD-51-FB60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.477736
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.06723
GSE223008_9_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE173232_4_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE110178_4_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCOR-22465074-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NEPRO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1491
H3K4me1_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE122101,GSE122103_3_v_4_ssu72_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TCF3	ENCODE Transcription Factor Targets	1.0	null
GSE225982_2_v_0_ezetimibe_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32508
CLPP_KO_GSE40207_399_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
dorsal part of m2A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.94532
JHH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06533
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68163
SMRT-22465074-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7091-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE95688_7_v_5_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:E20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.11256
MEWO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11511
GSE117643_1_v_0_irx5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ELK1	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JZ-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A3DL-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
imatinib_homo sapiens_gpl96_gds3045	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H1993	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-4.80828
STAT3-1855785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.20899
GTEX-VJWN-0426-SM-3GIJI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0131
GSE237426_0_v_1_eif4a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.61256
GSE131649_2_v_11_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE120612_4_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
azapropazone-6522	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
lymphnode_5b	HPA Tissue Sample Gene Expression Profiles	1.0	1.20218
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.6601
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.42394
ETS1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE89767_2_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
diazoxide-5810	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE201217_2_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
monocrotaline-2749	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K87180723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04689
Perturb_8539_KO_Notch2_SRP152804	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Lymphnode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.05834
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26396
BRD-K24396618	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3489
GSE60367_2_v_1_cxcr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K86711517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87272
minoxidil-1914	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5049-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ONCODG1	DepMap CRISPR Gene Dependency	1.0	2.72522
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K16694974	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0233
diagonal part of septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05582
CCND1	ChEA Transcription Factor Targets	1.0	null
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.81665
cerebellar white matter	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22582
MORCPR	CCLE Cell Line Gene CNV Profiles	1.0	1.77757
imatinib_homo sapiens_gpl96_gds3043	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN015_HEPG2_48H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.47581
GSE114883_0_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
metampicillin-2123	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE165682_4_v_3_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.89504
CRCGN017_MCF10A.WT.HP_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0157
TAL1	ChEA Transcription Factor Targets	1.0	null
Skin	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.8611
hsa-miR-298	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
CMK	CCLE Cell Line Gene Expression Profiles	1.0	1.41722
disease	GWASdb SNP-Disease Associations	1.0	0.025269
Perturb_1809_KO_Irf5_SRP186268	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.42784
Lung adenocarcinoma_LUAD_TCGA-78-8648-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	1.62713
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K26156776	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15324
globus pallidus, external segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18494
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5755
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-587	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
GSE226249_2_v_6_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.909269
Kidney renal papillary cell carcinoma_KIRP_TCGA-2K-A9WE-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-DX-A23V-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100315_TCx_no dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.64687
CRCGN016_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2224
sertaconazole-6811	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-U4B1-0008-SM-4DXUW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10538
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE142210_2_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
lasalocid-3360	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-5872-02A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE125403_7_v_6_venetoclax_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ATAD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34032
hsa-miR-2467-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XY-1626-SM-46MVN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.918038
AB-39-ED84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.247018
globus pallidus, internal segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12228
PHA-00851261E-4333	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
principal sensory nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.05356
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE181966_0_v_3_has2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20O-01A-21R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH650	DepMap CRISPR Gene Dependency	1.0	3.50932
STAT3-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4740-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A_48H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.16968
superficial stratum of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23673
dilazep-7364	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A6E9-06A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF7-22412390-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
azathioprine-5262	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K10564128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92025
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33982
SZ in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.863183
KA-75-LP02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.563765
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1145
GSE193258,GSE193259_9_v_8_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FC-20-EQ58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.780838
intermediate stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57239
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.028524
RAD21_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPARG-20176806-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CIAO2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45926
Rectum adenocarcinoma_READ_TCGA-EI-7004-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE213588_10_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE211983_0_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
midecamycin-1943	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
PMC8851354-Table_5.xlsx-Ruxolitinib_reg_FD-bound-Supplementary_Table_5_Genes_regulated_by_ruxolitinib_that_are_FUS-DDIT3_targets_in_MLS_402-91_cells_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K47217000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52676
GSE228894_0_v_2_rnmt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K89992188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57869
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XV7Q-0126-SM-4BRVK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34512
CRCGN016_MCF10A.WT.HP_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.36652
EMILIN complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.946
BRD-K74173779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04919
UACC-257	GDSC Cell Line Gene Expression Profiles	1.0	1.68629
GSE160246_9_v_1_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
arterial stenosis	GWASdb SNP-Phenotype Associations	1.0	0.264544
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MMAc-SF	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.24799
HCC44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.868577
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8T8-1426-SM-3DB9H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.882142
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4517
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00028
EGR1	ChEA Transcription Factor Targets	1.0	null
NRF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-20a	TargetScan Predicted Conserved microRNA Targets	1.0	0.265648
CRCGN016_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.52005
GSE225656_2_v_3_tsc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE185519_3_v_7_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PCM6	CCLE Cell Line Gene Expression Profiles	1.0	1.98699
BRD-K45421483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4857
canrenoic acid-7135	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
indometacin-452	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5789-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YN-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
metoprolol-6846	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SLC3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11263
clopamide-3220	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15304
GSE111660_2_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VM-A8C9-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
suprofen-4123	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN013_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.79188
GSE235066_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE223334_3_v_0_bcl11b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4492	TargetScan Predicted Conserved microRNA Targets	1.0	0.31417
IL12B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00546983
GTEX-X4EP-0526-SM-3P5YW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84346
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Retrosplenial area, lateral agranular part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56715
Lung squamous cell carcinoma_LUSC_TCGA-56-8082-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
haloperidol-1539	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE120612_7_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.08117
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.08513
BRD-K25064302	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69149
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.845075
GSE131649_6_v_9_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.901353
H3K27ac_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE114992,GSE114993_7_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE118794_2_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
REC1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.16423
CTCF	ENCODE Transcription Factor Targets	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YK-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cerebellar cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40114
GSE199204,GSE211619_4_v_1_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPM-1626-SM-2HMK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15139
CTCF_GM13977_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
benzonatate-6334	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FF-28-ES17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222712
11-deoxy-16,16-dimethylprostaglandin E2-7514	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-P4PP-0326-SM-33HC4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.913389
TCF12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE174701_5_v_8_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE44157,GSE44163_3_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4QS-0926-SM-48TBS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45836
BRD-K65796649	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81899
IPC298_SKIN	CCLE Cell Line Proteomics	1.0	2.05863
15220918-TableS1a	GeneSigDB Published Gene Signatures	1.0	null
BE-31-XV38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.517915
FTSJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07404
Pleckstrin homology domain	InterPro Predicted Protein Domain Annotations	1.0	null
CHD4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE203308_14_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE218580_1_v_5_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Primary B cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.59236
BC-52-WF67_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210896
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.825775
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.52559
PK-45H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.834994
CRCGN016_MCF10A.TP53.M_24H:E10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0274
medial tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09598
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3914	TargetScan Predicted Conserved microRNA Targets	1.0	0.107229
GSE213588_8_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE168458_1_v_3_disulfiram_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4490-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACTR10	Pathway Commons Protein-Protein Interactions	1.0	null
GSE230656_0_v_1_gsdmd_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
perimammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29465
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03041
GSE183413_1_v_2_ash1l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE191021_1_v_0_nono_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-3926	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE133516_5_v_6_kat7_human	RummaGEO Gene Perturbation Signatures	1.0	null
Edema	CTD Gene-Disease Associations	1.0	1.173
POLR2A_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
suxibuzone-5806	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
amphotericin B-5404	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-REY6-1226-SM-48FDR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.973349
LS-123	GDSC Cell Line Gene Expression Profiles	-1.0	-1.63431
MAFK_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9510835-Table_2.docx-1-ZBTB34_ZBTB34	Rummagene Transcription Factor Associations 2026	1.0	null
GSE69869_0_v_1_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE146612_2_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	1.0	null
MFN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16617
GSE144838_1_v_5_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AC-84-QG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.05934
GSE125025_2_v_3_lyl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K29246335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09318
Kidney renal papillary cell carcinoma_KIRP_TCGA-4A-A93Y-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XQ8I-1926-SM-4BOOK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.8881
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-A53D-01A-32R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NRM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08787
BRD-A63342325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06483
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K90744477	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56477
oleandomycin-1935	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHA-00745360-3907	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ChIP_CHD1_19587682	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
SN12C	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.0637
496100438_PCx_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.36591
lynestrenol-2037	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE142588_2_v_1_cinobufagin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6902611-40104_2019_400_MOESM2_ESM.ods-FA-SNA-Total_of_1_054_out_of_1_627_proteins_were_considered_for_analyses_65_SNAI1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE255432_7_v_2_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27301
CRCGN015_MCF10A_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.4897
GSE114690_1_v_3_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.51386
nafcillin-3323	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
methotrexate-6318	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.52389
CLPP_KO_GDS4791_541_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K41192068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53059
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3339
BRD-K50171760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05009
GATA1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RM2N-0326-SM-48FD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17268
TOP1MT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04555
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847757
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K98444789	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08052
CRCGN011_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4326
BRD-K28399883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19706
KAT2A	ENCODE Transcription Factor Targets	1.0	null
GSE128634,GSE128636_1_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FO-11A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chloropyramine-3350	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
nalbuphine-5820	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.910302
CRCGN017_MCF10A.WT.HP_24H:A14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1102
GTEX-T5JW-0126-SM-4DM6K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46846
GSE165307_1_v_0_gfi1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE110440_2_v_0_rad21_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-30c	TargetScan Predicted Conserved microRNA Targets	1.0	0.140752
BRD-K09553491	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62851
GSE128634,GSE128636_2_v_5_foxo1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cefmetazole-5868	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC11309649-medi-103-e37185-s002.xlsx-Sheet1-FOS_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM12891_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Ansiform lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.90453
TAF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K47881755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01626
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-0.917733
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.94368
496100330_PCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.48447
NCIH2004RT	DepMap CRISPR Gene Dependency	1.0	4.2499
hippocampus (hippocampal formation)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.903649
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	1.0	2.15792
GSE248858_6_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN012_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7557
DMS79	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55217
outer SZ in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33696
Prestwick-857-3355	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
niflumic acid-5490	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
JHUEM1	DepMap CRISPR Gene Dependency	1.0	7.16386
GSE71491_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Prestwick-1082-7267	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE120370_4_v_1_thrombin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
r6 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52099
REST	ENCODE Transcription Factor Targets	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0244
PMC12337709-mmc3.xlsx-Wild-type_vs_RAG1_KO_NK_cells-Unnamed_1_RAG1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Zfp36l2_deficiency_GDS3574_153_mouse_E14.5 fetal liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NFK9-1626-SM-3LK5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.899193
t69-brown-adipose_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	4.22909
spleen_3a	HPA Tissue Sample Gene Expression Profiles	1.0	1.535
HS172T	CCLE Cell Line Gene Expression Profiles	1.0	2.014
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	1.0	3.2201
GTEX-WHPG-1426-SM-3NMBB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962196
GSE205070_2_v_9_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.862372
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K61772027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66076
SKNFI	CCLE Cell Line Gene CNV Profiles	1.0	1.48017
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MK-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
khellin-1922	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
AC-43-ZC52_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.286236
CRCGN011_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.7182
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ETS1_ETS1	Rummagene Transcription Factor Associations 2026	1.0	null
TCF7	ChEA Transcription Factor Targets	1.0	null
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-2467-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
PDGFRB	Hub Proteins Protein-Protein Interactions	1.0	null
BRD-K98793503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08883
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.25967
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCIH747_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	2.29493
Lobule III	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17759
GSE202434,GSE202438_3_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
irinotecan-7530	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE228894_0_v_1_rnmt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE193282_2_v_0_cd44_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PUR1	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04478
SPI1-23127762-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K28391526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37847
foliosidine-6057	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883169
BE-81-QL64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.606229
SP1	JASPAR Predicted Transcription Factor Targets	1.0	null
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.863328
SP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neuroendocrine cell_Trachea_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
Perturb_6976_KD_ALOX12_SRP321060	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Prostate adenocarcinoma_PRAD_TCGA-HC-7079-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4196925-pone.0109760.s005.xlsx-Supp_Table_1_Genes_in_immune_mo-NFKB1_mod_NFKB1	Rummagene Transcription Factor Associations 2026	1.0	null
subpallial septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24522
Lung squamous cell carcinoma_LUSC_TCGA-43-6647-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LY-294002-5576	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE130081,GSE130082_4_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
benserazide-6482	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MA-AA42-01A-12R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K57795803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.116
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WRHU-0826-SM-3MJFN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889783
GTEX-POMQ-0126-SM-48TD6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68409
GSE261177_0_v_1_tnfrsf12a_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135030_11_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE213588_8_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
KIAA1033	Pathway Commons Protein-Protein Interactions	1.0	null
SP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16337
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-TEAD2_TEAD2	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4632	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
PMC9013128-NIHMS1795992-supplement-4.xlsx-501mel_ARID2_KO_Upregulated-Gene__name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K27915221	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64189
GSE240896,GSE240899_2_v_4_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE129241_4_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE147664_0_v_1_arid1b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PX3G-1026-SM-48TZW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917935
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A656-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3130-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GSE200352_4_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PRPF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.3922
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
striatum_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.839614
EP300_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3635
Lung adenocarcinoma_LUAD_TCGA-86-8671-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE128730_4_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
REST_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.79644
DD-75-HY40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.260848
VD-88-MW70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.252745
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE151612_0_v_7_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K42582718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.28872
p1 portion of the paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.04105
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AB-33-EM56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.58766
stratum pyramidale of rostral CA3	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.980613
GSE221327_6_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T6MN-0008-SM-4DM7H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01911
DOV13	DepMap CRISPR Gene Dependency	1.0	2.08997
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26094
Vasculature-macrophage	Tabula Sapiens Gene-Cell Associations	1.0	6.44175
BRD-K81314458	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21588
BRD-K53624506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19792
BC-62-RZ55_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.426679
GSE206516,GSE206518_3_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.01143
mantle zone of r10BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15679
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NERF2-26677805-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
increased macrophage apoptosis	MGI Mouse Phenotype Associations 2023	1.0	null
pineal_day	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.36527
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HDAC6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.15455
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.976463
COLO-792	GDSC Cell Line Gene Expression Profiles	1.0	2.11812
GTEX-OOBK-1626-SM-2HMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38102
hsa-miR-4498	TargetScan Predicted Conserved microRNA Targets	1.0	0.265648
PPARG-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
trimethobenzamide-1920	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZR75_1	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.93863
H3K4me1_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC9362915-pone.0272017.s004.xlsx-Day5_-0_7_Top-BBX_BBX	Rummagene Transcription Factor Associations 2026	1.0	null
TAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE190384,GSE190386_6_v_8_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
BD-49-MD69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.523657
intermediate portion of DFC (area 9/46)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.44288
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K85168571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15299
POLR2A	ENCODE Transcription Factor Targets	1.0	null
9+2 non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.563
layer V of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04611
CRCGN009_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.50973
GTEX-VUSG-0126-SM-4KL1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21101
CRCGN017_MCF10A.WT.HP_24H:N03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.18745
CRCGN015_MCF10A.TP53.M_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.4189
NCI-H2347	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE116810_5_v_1_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.WT.HP_24H:L11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03255
SPI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12871_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LN464	CCLE Cell Line Gene Expression Profiles	1.0	1.50184
periventricular stratum of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.9442
BRD-K03361106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07624
YY1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.93078
GSE138938_1_v_2_foxp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
m1AD (DM) part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.36474
SKMEL3	CCLE Cell Line Gene Expression Profiles	1.0	1.3648
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.05627
GSE217776,GSE217829_4_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	1.0	null
dexamethasone-2242	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE173873_10_v_13_stra8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_12hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TP73	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3593
LY-294002-5224	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN014_HEPG2_24H:A03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.86981
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	1.0	2.13634
CRCGN017_MCF10A.WT.HP_24H:G12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.54725
PMC12645189-MRD-92-e70068-s005.pdf-0-ZBTB8A_ZBTB8A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OIZF-1526-SM-3MJGY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904833
arteriosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.293189
GTEX-XUYS-0005-SM-47JZ2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948722
GSE160373_8_v_2_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF384_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ5-1726-SM-2I5F6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.83117
hsa-miR-519c-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.092495
GSE195568_3_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
KDM1A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA1_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETS1	ENCODE Transcription Factor Targets	1.0	null
GSE221577_4_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XMK1-0326-SM-4B652	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.939681
NCIH1944	CCLE Cell Line Gene Expression Profiles	-1.0	-1.7702
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07084
BRD-K33953218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.51954
MYBL2-22936984-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K36042673	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37672
GSE235066_4_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19708
H3K27ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE242199_2_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.28945
metamizole sodium-3754	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.24582
gata1_15860665_megakaryocytes_lof_mouse_gpl1261_gds1245	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.926892
Lung squamous cell carcinoma_LUSC_TCGA-56-7731-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K01121723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04691
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.28558
suramin sodium-7524	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CORL279	CCLE Cell Line Gene Expression Profiles	-1.0	-2.63149
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
superior occipital gyrus, left, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12143
GSE211226_1_v_0_sirpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE103068_0_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MOTN1	CCLE Cell Line Gene Expression Profiles	1.0	2.81545
PMC10831540-supplementary_table_1.xlsx-DEG_pc-S-EC2-pc-S-EC2_Compare_erectile_dysfunction_ECs_vs_normal_ECs_using_either_combined_ED_ED_DM_and_ED_nDM_or_ED_DM_and_ED_nDM_seperately_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE166004_5_v_4_pld1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9675280-12950_2022_317_MOESM2_ESM.xlsx-LPS_vs_control-Unnamed_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
0175029-0000-7392	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cinchonidine-2772	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7857-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inflammatory cell apoptotic process	GO Biological Process Annotations 2023	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WO-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QLQW-0326-SM-447A8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.992052
PRPH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23744
Medial preoptic nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31478
GSE130383_1_v_0_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE235587_2_v_1_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mesothelioma_MESO_TCGA-SC-A6LM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193624_1_v_0_med1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RUNX3	ENCODE Transcription Factor Targets	1.0	null
AF-73-HJ84_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.249627
AB-00-IL62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.356238
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.597738
GSE189653,GSE203344_4_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K64767126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07006
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chlortetracycline-1541	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-RTLS-0526-SM-2TF64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00387
TYKNU	DepMap CRISPR Gene Dependency	1.0	2.0346
CRCGN012_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.95478
iproniazid-2288	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CLPP_KO_GSE40207_382_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
mantle zone of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17175
prostate	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.839697
GTEX-P4PP-0926-SM-48TBZ	GTEx Tissue Sample Gene Expression Profiles	1.0	3.04987
BRD-K76543697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1539
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.5744
TMEM230	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16254
hsa-miR-548s	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
GSE195568_1_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0042
HS 675.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.41124
GSE139455_7_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DB-54-GQ68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.40917
GSE112761,GSE112767_2_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100504_TCx_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.3217
nalidixic acid-7367	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.79895
HCT-116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
VMRCLCP	CCLE Cell Line Gene CNV Profiles	1.0	2.42056
GSE58724_3_v_4_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MT-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55126
hsa-miR-3612	TargetScan Predicted Conserved microRNA Targets	1.0	0.088999
GSE210580_0_v_12_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Crus 2, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7701
BRD-K34519170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0937
SSU72	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22788
cell periphery	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
folic acid_homo sapiens_gpl2700_gds3656	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
doxylamine-1893	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Crus 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80925
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
motor nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12718
GSE126127_5_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	85.5551
GTEX-QV31-0226-SM-447BO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43972
hsa-miR-1	TargetScan Predicted Conserved microRNA Targets	1.0	0.348832
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE139455_4_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.0546
TBX20-22328084-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NELFE_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RS-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_6591_KO_Zcchc8_SRP187429	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
POLR2A_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE96641_5_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE100316_5_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
pancreas_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.01383
outer SZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.875111
Lung adenocarcinoma_LUAD_TCGA-49-6743-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormalities of the peripheral arteries	GWASdb SNP-Phenotype Associations	1.0	0.264544
mammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38072
diethylstilbestrol-4369	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
496100322_FWM_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.54685
TEAD4_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K02274100	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37389
GSE111385_2_v_1_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ficolin-1-rich granule lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.96
posteroventral (inferior) parietal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.8218
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cdkn1b_00000000_mouse_embryonic_fibroblast_mef_lof_mouse_gpl6246_gse27672	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.996912
KF-18-RY71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.331694
indoprofen-3345	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FOXG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45586
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.863328
SMAD4-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE214596,GSE214598_1_v_0_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_15650_OE_Trim59_SRP229490	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Pancreatic_Islets	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.3476
GSE195559_8_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CORL88	CCLE Cell Line Gene Expression Profiles	-1.0	-2.29625
BRD-K76353834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67698
GSE196259_2_v_0_gcm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WYVS-0006-SM-3NMA7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09836
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3425-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S3XE-0626-SM-4AD6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66112
GSE184087_0_v_3_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6456
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46709
intracellular organelle lumen	GO Cellular Component Annotations 2025	1.0	null
hsa-miR-4715-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
COLO741	CCLE Cell Line Gene Expression Profiles	1.0	1.55135
GSE221327_1_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Neurotoxicity Syndromes	CTD Gene-Disease Associations	1.0	1.0894
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10877
levopropoxyphene-3543	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_GM12867_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.903944
MEX3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28062
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
clenbuterol-5266	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
myeloid cell apoptotic process	GO Biological Process Annotations 2025	1.0	null
hycanthone-5691	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE201309_1_v_8_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
perphenazine-1956	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XXEK-1726-SM-4BRVB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49822
intracellular part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GSE210580_0_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Folium-tuber vermis (VII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20431
AB-97-BI36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.325724
CHD2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05959
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IRF8-27001747-CHIP-SEQ-BMDM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.976855
GSE135030_11_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.56124
BRD-K62979806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03567
Erg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.166
GTEX-TKQ2-0426-SM-4DXUO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.974082
KA-81-AG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.836359
Perturb_2041_KO_Abro1_SRP275730	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.01485
Simple lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69483
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.82076
OCUM1	CCLE Cell Line Gene CNV Profiles	1.0	1.88924
BRD-K62248885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07946
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ventral paracommissural tectal nucleus, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.73593
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B8-01A-31R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XGQ4-0126-SM-4AT4H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35791
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.43021
Perihypoglossal nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0149
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.22076
GTEX-QCQG-2126-SM-2S1P8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64661
GSE143212_1_v_2_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RNF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0338
delsoline-5858	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SDHAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32661
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PSDG-0426-SM-2S1OF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19026
BRD-K14246348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33247
BRD-K75252192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35082
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-3B-A9HO-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-51-4079-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE233049_1_v_0_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
AD-16-HL96_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.240433
CRCGN017_MCF10A.WT.HP_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.65865
dorsal motor nucleus of the vagus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.51321
Liver hepatocellular carcinoma_LIHC_TCGA-GJ-A3OU-01A-31R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE235587_2_v_0_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.91321
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.50975
BRD-K54881917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21787
BRD-K65166009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03493
BRD-K31747470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16736
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
aztreonam-2118	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.69265
JUND_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE88819_0_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25529
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7382-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.89274
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46456
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WM-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU2F2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CORL24	CCLE Cell Line Gene Expression Profiles	-1.0	-1.77029
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880692
succinylsulfathiazole-2821	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MTA3	ENCODE Transcription Factor Targets	1.0	null
GTEX-TMZS-0326-SM-3DB9P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36771
EHEB	CCLE Cell Line Gene Expression Profiles	1.0	1.9224
P2URK562	DepMap CRISPR Gene Dependency	1.0	2.20483
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.10248
Microglial cell_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
GSE210580_3_v_12_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE184210_0_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K77519898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04717
BRD-K76431854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30119
GSE256181_1_v_0_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K22216962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47408
PMC7293310-41467_2020_16179_MOESM8_ESM.xlsx-Table_S9_GATA1_WT24h_vs_SET24-Unnamed_9_GATA1	Rummagene Transcription Factor Associations 2026	1.0	null
SMARCA4	ChEA Transcription Factor Targets	1.0	null
PHA-00846566E-7086	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890938
GSE140997_4_v_6_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH1092	CCLE Cell Line Gene Expression Profiles	-1.0	-2.14356
17660535-TableS4b	GeneSigDB Published Gene Signatures	1.0	null
GTEX-WHSB-1826-SM-3TW8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62304
GSE158197_5_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.87261
GSE213588_8_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
SNU1105_CENTRAL_NERVOUS_SYSTEM	CCLE Cell Line Proteomics	1.0	3.19315
ERF_02_34	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59052
GSE162276_2_v_3_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE150669_2_v_3_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SPI1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-SJXC-1226-SM-4DM78	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.37106
GSE213588_10_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9084694-RMB2-21-e12464-s005.xlsx-GV_MI_MII_GV-up-GeneName_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-5333-01A-01R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
PMC8242083-41467_2021_24064_MOESM4_ESM.txt--HSF1_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VJYA-0126-SM-4KL1P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86468
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7359
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.11608
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE159678_6_v_7_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:L09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.34565
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE172490_5_v_3_junb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
scoulerine-2891	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CEBPB-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
LA-42-ER00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.06281
primary auditory cortex (core)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.88452
GSE110178_1_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K42653521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83841
GATA1_G1E-ER4_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
clioquinol-5258	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.99427
BRD-K94876980	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94912
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BET1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55105
GSE114992,GSE114993_9_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
iopamidol-5832	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CCRF-CEM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K79221878	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09162
GTEX-RN64-0326-SM-2TC5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.0981
GTEX-S95S-0008-SM-4AT5M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890052
nabumetone-6487	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pineal_night	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.0414
Rectum adenocarcinoma_READ_TCGA-AF-2690-01A-02R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8016886-41419_2021_3630_MOESM6_ESM.xlsx-Sheet1-Table_S5_Differentially_expressed_genes_identified_between_HOXC6-low_and_HOXC6-high_expression_CRCs_using_TCGA_cohort_HOXC6	Rummagene Transcription Factor Associations 2026	1.0	null
RXRA::VDR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3
GSE57871_11_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
khellin-1504	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-QVJO-0126-SM-3GIK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17286
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15156
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07091
TAF1_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-DEG_MDDC_C91-PL_LPS_vs_MDDC_Jurkat_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26396
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-NB4-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_NB4_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
MECOM-23826213-KASUMI-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE242290_3_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE210580_4_v_12_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dorsal tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57239
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K28746174	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2031
Dorsomedial nucleus of the hypothalamus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06157
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.903944
GSE213588_9_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
LPIN1_OE_GDS2291_587_mouse_Liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19969
BRD-K69852452_F1566-0341_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K9ac_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE77108_0_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69977
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.998196
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5675-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE256181_2_v_0_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE111247_0_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
skeletalmuscle	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.18356
MYBL2	ChEA Transcription Factor Targets	1.0	null
GSE157036,GSE166411_3_v_1_halofuginone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ELK1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.56019
ELK3-25401928-HUVEC-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PARP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07587
GSE213588_9_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FA-63-WI26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.310564
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
DD-42-PC65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.529266
Folium-tuber vermis (VII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19999
GTEX-X3Y1-0726-SM-3P5YU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20131
Cerebellum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28979
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
Abducens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26581
MRPL51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09745
CTCF_GM12868_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AGXT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98314
josamycin-1950	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE119564_1_v_0_zfp217_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.9369
GSE214596,GSE214598_1_v_3_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RVPV-0011-R11A-SM-2TF6F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.949595
BRD-K35369722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95005
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K61124142	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01721
sulindac-5528	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE171837_3_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAVER1	DepMap CRISPR Gene Dependency	1.0	2.31561
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5358-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE142210_4_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-2964a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
BRD-K52232548	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92073
CRCGN015_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9564
Acute Myeloid Leukemia_LAML_TCGA-AB-2987-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4846
GSE171175,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
Crus 1, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.95724
hsa-miR-4713-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
BRD-K35001076	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24248
CTCF_GM12866_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K19220233_JNK-9L_BT20_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lobule III, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13419
Prostate adenocarcinoma_PRAD_TCGA-EJ-7330-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of m2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08141
CRCGN016_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.1547
primary motor-sensory cortex (samples)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1715
BCB000039-7531	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
loperamide-1949	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K30318008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.47517
GSE168401_1_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100485_PCx_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0209
pheniramine-1910	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-X261-0326-SM-3NMD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892848
CRCGN008_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.71945
GSE235066_7_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
IGR-37	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.87689
GTEX-U8XE-1826-SM-4E3HV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936744
GSE210580_5_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
amoxapine-1513	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
GSE166920_6_v_5_adalimumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.52132
SP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06433
GTEX-RUSQ-0126-SM-47JWV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35056
paraventricular nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20783
GTEX-U8T8-0008-SM-4DXSP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06522
co-dergocrine mesilate-4152	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8201-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEL-HO	GDSC Cell Line Gene Expression Profiles	1.0	2.07035
ficolin-1-rich granule	GO Cellular Component Annotations 2023	1.0	null
CTCF_astrocyte of the spinal cord_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A_48H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.34207
molsidomine-5426	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE109530,GSE109531_2_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SPI1	ENCODE Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IJ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of pedal digit skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE144443_5_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE68156_3_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OOBK-0226-SM-2YUMF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84385
JD-44-KF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.955929
BC-40-TU13_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.300711
cromoglicic acid-3475	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SK23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.904966
GTEX-WVLH-0011-R11A-SM-3MJFO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13524
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988991
GTEX-U3ZN-2226-SM-3DB88	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.996744
SNU520	CCLE Cell Line Gene Expression Profiles	-1.0	-1.71862
lateral hemisphere of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.929074
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.61242
PMC3435504-msb201237-s2.xls-Supp_Table_4a-SP1_SP1	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.64496
posterodorsal tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32914
acenocoumarol-5878	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Crus 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.0049
semustine-7487	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SUZ12	ENCODE Transcription Factor Targets	1.0	null
cefsulodin-4148	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE148252_7_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XAJ8-1026-SM-47JY9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57026
BB-87-SF89_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.622942
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.67468
CRCGN017_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.70545
captopril_mus musculus_gpl1261_gds3683	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE120612_7_v_2_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-UPIC-0726-SM-3GADW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06847
GATA1_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RUNX1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
paracentral lobule, posterior part, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.997635
CRCGN013_HEPG2_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.53921
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.35891
Uterine leiomyoma_Uterus - Myometrium (MMHCC)_GSE593	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.66976
meticrane-1834	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879779
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.89989
MAFF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZEB1	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-3135	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
primary auditory cortex (core)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.895552
GSE158456_1_v_3_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE100316_7_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MYB-21317192-ERMYB-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
POLR2A_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P78B-1326-SM-3P611	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03477
Chondroblastic osteosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.371
mast cells	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.0011
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5ED-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
PMC10831540-supplementary_table_1.xlsx-DEG_pc-S-EC2-Unnamed_32_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
SMAD2/3-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PML_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JW-0008-SM-4DM5X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938292
CTCF_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K60267900	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02225
zoxazolamine-6290	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE210101,GSE210114_5_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
Tic complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.911
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K09144377	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07845
POLR2AphosphoS5_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
coronary artery disease	GWASdb SNP-Disease Associations	1.0	0.971169
urapidil-6455	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2AphosphoS5_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMR6-0011-R11A-SM-32PKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12209
H9 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.956552
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08564
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.925776
GTEX-PLZ4-0926-SM-2S1OI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01849
deferoxamine-460	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K21997380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.1335
FOXJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35191
BRD-K49031847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13799
cytoplasm	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
CRCGN016_MCF10A.TP53.M_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.37607
ATG9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03245
CRCGN015_HEPG2_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.06098
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05118
GSE184884_2_v_1_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE211474,GSE212779_0_v_1_phf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NDUFA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66123
fisetin-579	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
WC-16-IR43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.560743
Bone marrow cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TCCPAN2_PANCREAS	CCLE Cell Line Proteomics	1.0	2.08225
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0217
H9	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.81367
GATA1	ChEA Transcription Factor Targets	1.0	null
CRCGN016_MCF10A.WT.HP_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.50005
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SP-01A-31R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.TP53.M_24H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6947
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_17213_OE_EWSFLI_SRP261076	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.13539
r7 part of nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05087
SP4	ENCODE Transcription Factor Targets	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
labetalol-3167	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MEIS1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TCF7L2_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cinchocaine-4068	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE143212_0_v_3_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Paraflocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22877
hsa-miR-519b-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.092495
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.225056
BRD-K83569804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18253
CRCGN017_MCF10A.TP53.M_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4917
superficial stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.95596
CRCGN016_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.19166
GSE213588_9_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10709
GSE96991,GSE97117_4_v_2_il11_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE206729_4_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22039
H3K27ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PRKCA_knockdown_118_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.99925
ELK1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE226249_5_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.0763
AA-22-UI44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.828451
cefadroxil-4161	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A75O-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6521
PMC8410861-41467_2021_25544_MOESM32_ESM.xlsx-MCR-MCR_cells_-_DGE_iGCA_testis_vs_adult_testis_from_GSE112013_and_GSE124263_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.052119
GSE213410_2_v_3_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kinocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.563
PMC11699013-12672_2024_1699_MOESM1_ESM.xlsx-Supplementary_Table_2-Supplementary_Table_2_The_association_between_proteins_and_CLL_in_the_MR_analysis_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE189653,GSE203344_2_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PCI-4B	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.8453
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956035
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K33453127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45515
MED26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.589
GSE135352_0_v_4_napabucasin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K55584718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11937
GSE231720,GSE231724_2_v_1_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32214
Chloroplast membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.862
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.839614
GSE68156_0_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CCND1-20090754-RETINA-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.2742
calcium folinate-3442	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.60891
bupropion-3180	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BF-11A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K73528610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86928
GTEX-XPVG-0626-SM-4B65B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22426
BRD-K03194507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55762
labetalol-6809	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
IRF1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S33H-1226-SM-4AD69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.985444
GTEX-T8EM-0826-SM-4DM76	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846707
GTEX-XXEK-0126-SM-4BRVU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68414
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82201
metitepine-5413	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.28388
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K77547131	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00429
GSE180951_2_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2AphosphoS5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.35431
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05582
GTEX-QDVJ-0008-SM-48U2E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886838
EGR1	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-RNOR-0526-SM-2TF4O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28206
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.12463
Lung squamous cell carcinoma_LUSC_TCGA-60-2709-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
glibenclamide-3163	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.15597
BRD-K30217326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3816
viomycin-7278	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
inner portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32835
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K74789550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03997
CRCGN016_MCF10A.TP53.M_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.00452
CRCGN014_HEPG2_3H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6167
GSE193258,GSE193259_2_v_12_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K94514173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23638
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A183-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EY-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
repaglinide-5862	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
troglitazone-1232	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-OOBJ-0326-SM-33HBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.988451
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.20064
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-R2-A69V-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
m1 part of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53165
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.2582
MEL-HO	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.09107
SRF_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF7_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K77884956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06199
SMC3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4437	TargetScan Predicted Conserved microRNA Targets	1.0	0.065994
LD-69-ZV56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.336318
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.4075
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K37392901_NSC 632839 hydrochloride_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Sarcoma_SARC_TCGA-DX-A1L4-01A-12R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC3470785-NIHMS377161-supplement-3.pdf-367-CEBPG_CEBPG	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_10604_KO_Ncor1_SRP216477	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.63259
BRD-K46439376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98969
GSE254770_0_v_1_sin3b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HS571T	CCLE Cell Line Gene Expression Profiles	1.0	1.4227
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T5JW-1826-SM-3GAE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36691
Specific granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.601
BRD-K35726223	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.55011
Lung squamous cell carcinoma_LUSC_TCGA-46-3766-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K43271856	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27727
diprophylline-5482	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27ac_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRN-1326-SM-3LK5V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00215
Oviductal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.534
H3K9ac_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cell part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.28665
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.596
imatinib_homo sapiens_gpl96_gds3042	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE197257_0_v_1_gpd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9332
BRD-K45621617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08978
GTEX-UJHI-0126-SM-4IHLP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37093
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.07889
H3K79me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SPI1_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
17660535-TableS4a	GeneSigDB Published Gene Signatures	1.0	null
CDC7_knockdown_109_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.70805
GSE158197_0_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NFYB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
deferoxamine-3417	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KDM1A	ENCODE Transcription Factor Targets	1.0	null
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37453
dirithromycin-2863	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K54769228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61209
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17762
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12864_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08582
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.76687
primary motor cortex (area M1, area 4)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.30545
GSE158632_2_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE139992_2_v_3_mboat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
isthmus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04776
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
nfe2l2_20133372_lung_lof_mouse_gpl1261_gds3622	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.127556
BRD-K19862308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56894
inferior occipital gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.941446
globose nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.88528
BRD-K17185909	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14108
PMC4634137-ncomms9549-s7.xlsx-ZF_Hair_cell_data-Unnamed_1_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10731
CRCGN010_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.88653
ZNF197	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16008
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K10635555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24768
BRD-K60760423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2846
tamoxifen-2050	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47966
BRD-K24877937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17528
SW1463	DepMap CRISPR Gene Dependency	1.0	2.77323
EGR1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.41692
posteroventral (inferior) parietal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00114
H3K4me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SUDHL10	DepMap CRISPR Gene Dependency	1.0	9.64182
COLO775	CCLE Cell Line Gene CNV Profiles	1.0	1.35668
TBX20-22080862-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K62624148	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41414
HCC-366	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.68135
spleen	HPA Tissue Protein Expression Profiles	1.0	1.28518
GTEX-WH7G-0826-SM-4LVMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40475
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.873273
lateral part of MM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36436
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Tcof1_OE_GDS998_154_mouse_neuroblastoma N1E-115 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE114992,GSE114993_7_v_3_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
15(S)-15-methylprostaglandin E2-7489	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K03608799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1961
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE137818_3_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
laterodorsal part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02458
Uterine Carcinosarcoma_UCS_TCGA-ND-A4W6-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT1	ENCODE Transcription Factor Targets	1.0	null
GSE228413_2_v_5_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CASR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00527202
butoconazole-5388	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE210580_5_v_2_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
Alzheimer's Disease_CNS - Brain - Hippocampus (MMHCC)_GSE1297	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.90448
BRD-K27885385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34956
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_12792_KO_Tgfbr2_SRP133892	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.29258
dinoprost-3308	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
paromomycin-3356	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hydrastinine-5494	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SIRT3_KO_GDS4058_16_mouse_BROWN ADIPOSE TISSUE	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE152441,GSE152442_0_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K32000549	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7468
AA-23-FM46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.30744
GTEX-Q2AH-0726-SM-2I3EA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906867
hsa-miR-4456	TargetScan Predicted Conserved microRNA Targets	1.0	0.085563
Perturb_11985_KD_STAT3_SRP330023	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.1081
KDM4A	ENCODE Transcription Factor Targets	1.0	null
P53-22127205-FIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_15875_KO_Atoh1_SRP002802	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.49674
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UACC-257	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.30443
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6754
GSE186633_2_v_0_chd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE101527_0_v_1_smad4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
S1PR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02251
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ6-1526-SM-2S1OC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1453
HNT-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.956656
streptozocin-7193	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Vestibular hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.502
UACC257	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
GTEX-SNOS-1526-SM-32PLW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32593
Lung squamous cell carcinoma_LUSC_TCGA-77-A5FZ-01A-31R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Chloroplast inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.907
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-8537-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DDX51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06556
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE81803,GSE81912_3_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A182-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AE-39-DG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.830011
CRCGN014_HEPG2_24H:J15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.83885
Prostate adenocarcinoma_PRAD_TCGA-TK-A8OK-01A-22R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPL13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67199
hydrocotarnine-2765	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K23166347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81431
BRD-K36003376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64561
COCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46709
SP1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K47694606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52939
GSE148066,GSE157787_8_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K36445086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63285
tribenoside-5429	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K77139764	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35549
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF-_SURVIVAL-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
ZC3H11A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Stereocilium bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.867
GSE166169_1_v_3_elp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE221577_3_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE169152_5_v_6_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
promazine-3833	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-R55F-1226-SM-2TF59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.927481
tetroquinone-4159	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN015_MCF10A_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.12298
scopolamine N-oxide-5436	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
myeloid cell apoptotic process	GO Biological Process Annotations 2023	1.0	null
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
primary auditory cortex (core)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.77576
RPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85321
SPI1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04768
RPS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25447
FB-66-UU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.750772
BRD-K67950754	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37001
CLC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59664
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE203329_2_v_1_mettl5_human	RummaGEO Gene Perturbation Signatures	1.0	null
doxylamine-1473	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Umbilical artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.651
ZNF664	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05041
hsa-miR-920	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
HLFA	CCLE Cell Line Gene Expression Profiles	1.0	1.76655
POLR2A_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K68328788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2893
Perturb_14144_KD_HK2_SRP322804	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.6943
LMO2	ChEA Transcription Factor Targets	1.0	null
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.915766
BRD-K36940835	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06881
GSE92457_7_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.835651
HCC15	DepMap CRISPR Gene Dependency	1.0	3.09725
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
deep layers of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.851342
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44734
UKE-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.898041
substantia nigra reticulata, isthmic part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22614
GTEX-WZTO-3026-SM-3NMA2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879246
chlorzoxazone-2100	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
clomipramine-3182	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-Q2AH-0226-SM-48U1I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18258
GSE84148,GSE96938_0_v_1_nrros_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Paramedian lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43849
disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.043246
Type 2 diabetes mellitus_Muscle tissue_GSE12643	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.56334
sulfasalazine-2882	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
equilin-5620	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCAPG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99011
Medial septal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05087
fluphenazine-3194	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Atrophy	CTD Gene-Disease Associations	1.0	1.07947
PMC4498179-srep11671-s1.pdf-246-SOX7_SOX7	Rummagene Transcription Factor Associations 2026	1.0	null
TAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
upper dorsal perifornical nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62028
HCC1954_BREAST	CCLE Cell Line Proteomics	1.0	2.01394
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.7076
GSE100102_0_v_6_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7260947-pnas.1912355117.sd02.xlsx-Sheet1-1185_common_genes_in_D_E_genes_KD_and_AcAPE1_ACOGG1_G4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.993399
naphazoline-1466	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K79067166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53509
Perturb_15542_KD_Map3k7/Chd1_SRP201304	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Photoreceptor proximal connecting cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.747
GSE220520_5_v_9_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
624 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20666
GSE174498,GSE174500_0_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
simvastatin-3340	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Spinal Muscular Atrophy, Infantile_CNS - Spinal Cord (MMHCC)_GSE3075	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.10066
BRD-K43435656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20133
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.57357
GTEX-UTHO-0011-R11A-SM-3GIJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.00842
PMC6571000__F6	PFOCR Pathway Figure Associations 2024	1.0	null
A361	BioGPS Cell Line Gene Expression Profiles	1.0	1.1008
GSE205913_1_v_0_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
COLO668	CCLE Cell Line Gene Expression Profiles	-1.0	-2.04887
SMC3	ENCODE Transcription Factor Targets	1.0	null
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.976855
CREB_DEPLETION_GDS3487_41_human_K562 myeloid leukemia cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-R55F-1526-SM-2TF4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2519
PMC10203545-Table_4.xlsx-LM7_underrepresented-DMRTA1_DMRTA1	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH2122	CCLE Cell Line Gene CNV Profiles	1.0	1.62842
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE134316_1_v_0_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE136397_1_v_0_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GATA1_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
homatropine-5477	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EBC1	DepMap CRISPR Gene Dependency	1.0	14.2893
Epristeride	DeepCoverMOA Drug Mechanisms of Action	1.0	0.2
GSE139992_1_v_0_mboat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7328-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE184892_0_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HD-51-KD29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.552342
GTEX-S32W-2326-SM-2XCAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12908
Perturb_11213_OE_arcA_SRP351667	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.80091
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8208-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
alfaxalone-6514	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.58988
EBF1	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRO-0226-SM-3LK6F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877949
GSE149264,GSE149267_4_v_5_trp53_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2836-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A8BQ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XBED-0226-SM-47JY8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842439
Simple lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65576
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T5JC-0626-SM-3NMA6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21875
SC-19220-7060	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
23132-87	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.62424
HOS	GDSC Cell Line Gene Expression Profiles	1.0	2.02763
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-7085-01A-21R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.34821
BRD-K01916633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67504
GSE149760_3_v_5_elof1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Heart Defects, Congenital	CTD Gene-Disease Associations	1.0	1.09083
PMC6855629-pone.0225186.s009.xlsx-Sheet1-DEGs_downregulated_in_HEK293_MEIS1_KO_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SQ1_LUNG	CCLE Cell Line Proteomics	1.0	3.17564
cyanocobalamin-3252	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Measles Chicago-1_24Hour_16492729_GSE980	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.26572
PTPRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42885
dorsal paracommissural tectal nucleus, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.50051
CRCGN017_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.98352
Hand1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.6893
chlorpromazine-1700	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GPRASP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60899
Anteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13069
SKG-IIIA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
periventricular stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20664
CRCGN016_MCF10A.WT.HP_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0905
Crus 2, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.84021
GTEX-X4XX-0011-R11A-SM-46MWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850181
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.582386
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73358
cortex of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23707
pipemidic acid-6470	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7647
BRD-K96799727_-666_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE225218_2_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN013_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.39157
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25575
BRD-K91423144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73611
GSE114992,GSE114993_9_v_11_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE116810_5_v_3_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
mepacrine-3179	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NKX2-6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09811
GSE223908,GSE223909_1_v_3_serpinb3_human	RummaGEO Gene Perturbation Signatures	1.0	null
amoxapine-6650	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K31584969	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38049
cefoperazone-5424	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.83549
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.35989
CD14+_Monocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.11522
superficial stratum of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63209
estradiol-665	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-4632-11A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
r10 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45258
Thyroid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.924666
CTCF_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ERG_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
clebopride-2646	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-TKQ1-0226-SM-33HB5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877882
CTCF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE179974_3_v_5_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.01052
BRD-K52862624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04042
GSE240027,GSE240030_5_v_0_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
clonidine-6814	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PD-70-VS77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.929879
GTEX-Q734-0226-SM-48U1A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6615
GSE163920_1_v_0_sirt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE179531_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.5997
LRRC16A	Pathway Commons Protein-Protein Interactions	1.0	null
macrophage apoptotic process	GO Biological Process Annotations 2023	1.0	null
RERFLCKJ	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45471
Lung adenocarcinoma_LUAD_TCGA-44-2661-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_MEL cell line_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r7 part of the nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43463
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.784861
cortico-medial group, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.14255
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE173873_10_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cell body membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.061
CRCGN015_MCF10A.TP53.M_24H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3793
Adrenocortical carcinoma_ACC_TCGA-OR-A5JQ-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.7491
CTCF_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC30A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57629
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
levamisole-2257	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
internal granular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60089
proxymetacaine-5433	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42732
Lung squamous cell carcinoma_LUSC_TCGA-60-2709-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SC-8002 (ESR1)	NURSA Protein Complexes	1.0	null
Sarcoma_SARC_TCGA-DX-A8BK-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS2_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.6657
debrisoquine-1591	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE167324_2_v_0_eif4e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.863328
CTCF_GM12870_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE190555,GSE190557_2_v_0_chd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
OF-05-CB18_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227789
ZMIZ1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bepridil-2629	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3WC-11A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8059
troglitazone-431	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
bone	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.897692
CTCF_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148066,GSE157787_11_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
salivarygland_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0153
raubasine-5459	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-OHPL-0326-SM-33HC8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00969
TEAD4	ENCODE Transcription Factor Targets	1.0	null
COLO741	CCLE Cell Line Gene CNV Profiles	1.0	2.25124
647V	CCLE Cell Line Gene CNV Profiles	1.0	1.68307
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K78873216	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11909
FOXS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10734
hsa-miR-3134	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
ZNF282	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.6591
DB-21-FY75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.259858
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142210_3_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26306
GSE202284,GSE202289_5_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
tretinoin-5767	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4890-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCL11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63618
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE110524_2_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SMU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5462
POLR2A_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158456_2_v_3_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE62292,GSE62295_2_v_0_col4a3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6989-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
interstitial nucleus of Cajal, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.862733
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.25776
mammillary area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38072
SKOV3	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.874198
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
morphine_mus musculus_gpl6246_gse17731	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE136742,GSE136744_0_v_3_setd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1897	CCLE Cell Line Gene CNV Profiles	-1.0	-1.83067
nadide-7227	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
facial motor nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.882782
naftidrofuryl-2622	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN010_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43712
GTEX-RTLS-0008-SM-48FET	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0518
Gonadal endothelial cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-143	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
EP300_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prestwick-682-6638	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJHI-1726-SM-3DB9B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44993
Acute Myeloid Leukemia_LAML_TCGA-AB-2851-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.90481
CRCGN016_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.00265
CRCGN015_MCF10A.TP53.M_24H:F22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9883
GSE223540_1_v_3_anxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S341-1226-SM-4AD5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.861033
Paraflocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24743
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19236
HS 255.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.61113
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K52123365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.08422
ceftazidime-5054	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
corticosterone-4145	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EC-62-OE64_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.212692
GSE135030_3_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNU1214	CCLE Cell Line Gene CNV Profiles	1.0	1.70159
EF-80-OD07_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.238647
amiprilose-4119	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE201309_5_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9ac_Rectal Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE144838_4_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883232
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE135352_2_v_3_napabucasin_human	RummaGEO Drug Perturbation Signatures	1.0	null
COX6B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51362
SNU738	CCLE Cell Line Gene CNV Profiles	-1.0	-2.17675
BRD-K38969544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57984
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.43825
GSE184892_7_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K37161540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22201
lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04685
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.8091
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BCL3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.09319
GSE148066,GSE157787_8_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZSCAN31	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.564
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.238
BRD-K95410891	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18371
ventral part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65013
calcium folinate-7401	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84517
Perturb_1505_KO_Tnfaip3_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.0771
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29X-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3C1-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53904
salivary gland	HPA Tissue Gene Expression Profiles	-1.0	-0.833309
GSE210101,GSE210114_4_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE98705_1_v_0_mdm2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8948659-ADVS-9-2104491-s013.xlsx-Sheet1-Supplemental_Table_9_related_to_Figure_7_Differential_genes_highly_correlated_with_TP53_deletion_in_H929_cells_by_RNA-seq_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Adrenalgland	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.879943
CTCF-27219007-CHIP-SEQ-ERYTHROID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-RWSA-1426-SM-47JXA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.922413
hsa-miR-4756-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.23348
TAF7	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-90-7767-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUN_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Doramapimod	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.3
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5152
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MFNG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22533
GTEX-U3ZH-0326-SM-3DB7A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826441
GSE114883_1_v_5_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
oltipraz	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.103
CRCGN009_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12746
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.861153
blood	GTEx Tissue Gene Expression Profiles	1.0	1.1898
oxytetracycline-3170	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PRPF40A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6098
sirolimus_homo sapiens_gpl8300_gds3603	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K68361061	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21086
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 800	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.21284
Paramedian lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63455
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RN64-1826-SM-48FDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75657
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pramocaine-4368	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA1	ENCODE Transcription Factor Targets	1.0	null
H2BK5ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC7291745-12967_2020_2407_MOESM2_ESM.xlsx-Table_S1D_CCF_pairs-locus_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
CF-65-GU65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.311546
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.874987
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K71870778	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20544
glycopyrronium bromide-7386	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
clofilium tosylate-3187	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7783-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_K562_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25931
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5108-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEATR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24312
pyrimethamine-1894	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H1573	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE229973_4_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
inferior occipital gyrus, left, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.904931
r8 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41394
KYSE-140	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-4.81033
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.58654
heliotrine-3615	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V1D1-2426-SM-3GAER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41477
TMPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08007
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE144838_1_v_8_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55058
GSE77108_6_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6348-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
probucol-5261	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.837798
Lung squamous cell carcinoma_LUSC_TCGA-39-5040-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chr15_64891751_C_A_b38	GTEx eQTL 2025	1.0	1.32342
HOMER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54396
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.744
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN009_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.48758
GSE239541_11_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
QA-50-YO37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.25722
indometacin-5468	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FLI1	ENCODE Transcription Factor Targets	1.0	null
GSE114992,GSE114993_7_v_10_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary hematopoietic stem cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.03455
Hodgkin lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.5
E2F6	ENCODE Transcription Factor Targets	1.0	null
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K63964208	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42229
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
CRCGN015_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.41169
aciclovir-5278	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K12986423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00673
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.623813
TRMT10C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26832
CTCF_fibroblast of foreskin _hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.45274
GSE136233,GSE136234_0_v_1_zpbp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8554124-DataSheet2.XLSX-57-CEBPD_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
SCCOHT1	DepMap CRISPR Gene Dependency	1.0	2.74707
GSE58724_3_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
famprofazone-6029	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE149903_3_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE197562_0_v_3_nox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DA-35-DU85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.444713
IRAK1_knockdown_115_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.65524
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.903398
GSE101239_4_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
indapamide-2322	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
ethambutol-1900	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BCL3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.881239
YWHAE	Pathway Commons Protein-Protein Interactions	1.0	null
pizotifen-6513	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38964
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A3Z3-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.99047
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gemfibrozil-5069	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_10375_KO_Fdft1_SRP285919	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.31456
GSE228413_4_v_3_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN013_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13882
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5080-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CC-68-YZ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.78071
flurbiprofen-5269	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LS_3min_LPS vs ctrl_RAW264.7_macrophage (Mouse) [20222745]	SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Drugs	1.0	null
josamycin-5692	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K23432132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04078
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fipexide-5737	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
etofylline-5467	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SCLY	ChEA Transcription Factor Targets	1.0	null
E2F1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE110178_2_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PFSK1	DepMap CRISPR Gene Dependency	1.0	2.24199
POU2F2	ENCODE Transcription Factor Targets	1.0	null
ChIP_SETDB1_19884257	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
aklomide	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15611
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.912467
GTEX-PW2O-1726-SM-2S1OO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876974
Spleen	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	2.85184
GTEX-PWN1-1626-SM-2S1OL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6726
GTEX-SIU7-0926-SM-4BRX1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.978311
Lung squamous cell carcinoma_LUSC_TCGA-22-5472-11A-11R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K04336022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00964
hsa-miR-4770	TargetScan Predicted Conserved microRNA Targets	1.0	0.31417
GSE120612_7_v_3_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
periventricular stratum of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52099
YD8	CCLE Cell Line Gene Expression Profiles	1.0	1.39012
CTCF_GM12864_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MALME3M	CCLE Cell Line Gene Expression Profiles	1.0	2.28994
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1307
496100340_TCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.25293
CRCGN015_HEPG2_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.76675
GSE210580_3_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COL5A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05062
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.04062
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HT115_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	3.97192
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1457
BRD-K55392659	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13979
KDM5B	ENCODE Transcription Factor Targets	1.0	null
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55449
Lung adenocarcinoma_LUAD_TCGA-38-4626-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-DX-A2J1-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor-sensory cortex (samples)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.958411
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31302
0317956-0000-3858	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CHD4	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A13I-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA1_G1E-ER4_mm9_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
inner SZ in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.989978
BRD-K84974041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13029
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PP-0526-SM-2HMKE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03658
GTEX-WK11-2526-SM-3NM9Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75016
SMC3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX5	ENCODE Transcription Factor Targets	1.0	null
HCC1833	CCLE Cell Line Gene Expression Profiles	-1.0	-1.68874
Kidney Chromophobe_KICH_TCGA-KN-8419-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIX5_02_78	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60235
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
leflunomide-5884	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PBX3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nadide-5873	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_fibroblast of lung_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.939225
H3K4me1_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DEOC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.80272
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NR-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDK6_knockdown_93_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.03731
GSE214596,GSE214598_1_v_2_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A03940741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00504
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.943937
hypoglossal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.82745
GSE129389_0_v_4_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7582-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE200352_1_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
bacampicillin-4592	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K79735667	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23055
ficolin-1-rich granule	GO Cellular Component Annotations 2025	1.0	null
hsa-miR-613	TargetScan Predicted Conserved microRNA Targets	1.0	0.37496
AD-16-HL96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.740748
hsa-miR-4732-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
CTCF_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RH00511	DeepCoverMOA Drug Mechanisms of Action	1.0	0.28
GTEX-QVJO-0008-SM-447AU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95517
peduncular subparaventricular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0062
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23533
SPI1-23127762-K562-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
HELA	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.89338
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A_48H:P07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.05841
cytokine cytokine receptor interaction	KEGG Pathways	1.0	null
Paramedian lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52578
PMC9314667-Table_1.xlsx-Regulons-IRF4_IRF4	Rummagene Transcription Factor Associations 2026	1.0	null
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1770	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.84507
Lung	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.950547
GSE133764_2_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_2_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE114992,GSE114993_7_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
benzethonium chloride-6070	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
fat_8a	HPA Tissue Sample Gene Expression Profiles	1.0	1.08896
posteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41469
BRD-K41322154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29158
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877129
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-93	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47966
t69-brown-adipose_male_8w	MoTrPAC Rat Endurance Exercise Training	1.0	1.33883
gabapentin-5875	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Tuberomammillary nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.94054
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE137818_2_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sulfadimethoxine-7400	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TNKS1BP1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78846
TCF12	ENCODE Transcription Factor Targets	1.0	null
GSE234043_3_v_1_abcb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE206270_1_v_0_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1822
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-5398-01A-02R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K35407043	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55096
BRD-A36938160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38001
GSE112860_0_v_8_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_11579_KO_QPC_SRP166848	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.41002
TRRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45794
NB-80-IM48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.435065
trichostatin A-5511	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
sulfamonomethoxine-7200	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCFC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142684_4_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K69438930	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20582
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	46.5869
TFAP2C	ChEA Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-8007-11A-01R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chlortalidone-3198	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE140997_10_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6326-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.62736
GTEX-SE5C-0626-SM-2XCDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856082
GSE160373_1_v_2_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
diethylcarbamazine-7425	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43576
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45156
GTEX-X261-0011-R11A-SM-4E3JY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.92408
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77722
sclc21h	HPA Cell Line Gene Expression Profiles	-1.0	-2.00775
BRD-K47049026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35953
OVCAR3	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.20636
Inferior colliculus, dorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09572
CBX3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K77207661	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36674
GTEX-QDT8-0226-SM-32PL4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918165
GSE128099,GSE128159_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
paclitaxel-1959	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PML	ENCODE Transcription Factor Targets	1.0	null
dorsolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.973874
U266B1	CCLE Cell Line Gene CNV Profiles	1.0	1.38868
GSU	CCLE Cell Line Gene Expression Profiles	-1.0	-1.78274
GTEX-XUJ4-0226-SM-4BOP8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15659
GSE234340_12_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE160246_9_v_7_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6643
H2BK20ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4861-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
heptaminol-7313	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
roxarsone-5470	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6515-01A-21R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE113221,GSE113968_4_v_1_prdm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MDA-MB-415	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-WN-A9G9-01A-12R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K00808919	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.59153
SKMEL31	CCLE Cell Line Gene Expression Profiles	1.0	1.41992
maprotiline-6676	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K83645749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34501
M14	BioGPS Cell Line Gene Expression Profiles	1.0	1.01086
GSE155852_0_v_2_apigenin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.73635
KOSC-2	GDSC Cell Line Gene Expression Profiles	-1.0	-2.13912
HCMV_4Hour_20173022_GSE11408	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.9073
GSE231799_3_v_1_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-P44H-0426-SM-2XCEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30681
USH2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.832
CRCGN008_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9646
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28496
GTEX-XUJ4-2626-SM-4BOQ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38132
Digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE135030_8_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.897452
Fatty Liver	CTD Gene-Disease Associations	1.0	1.19737
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prestwick-983-7480	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893456
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
haloperidol-5604	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8109
PMC12337709-mmc3.xlsx-Wild-type_vs_RAG1_KO_Myeloid-Unnamed_1_RAG1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE218580_1_v_3_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CDC42SE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50549
imipenem-2873	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE172490_5_v_1_junb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K41809257	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43198
CTCF_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.51112
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34281
GSE196259_1_v_3_gcm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178255_2_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventral claustrum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.923586
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M8-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMAD3-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE142210_4_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Declive (VI), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72388
BD-96-HO33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.364023
MADD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5858
Sarcoma_SARC_TCGA-MB-A5Y9-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4292	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
GSE124410_2_v_0_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
septal organ	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.81589
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE135030_11_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PML_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-H9-A6BX-01A-31R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67X-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K65752097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6429
CRCGN012_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7073
hsa-miR-762	TargetScan Predicted Conserved microRNA Targets	1.0	0.32519
GSE167886_2_v_0_chd7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC1806_BREAST	CCLE Cell Line Proteomics	1.0	2.49876
acetylsalicylic acid-1204	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K03849840	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90869
Perturb_17309_KO_Ddx25_SRP247988	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
epivincamine-2775	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39431
Sarcoma_SARC_TCGA-DX-A7ET-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
core of nucleus accumbens	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.908527
CHAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28299
r7 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85518
LF-94-HB11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.844536
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE88819_7_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K14865132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64076
DCTN4	Pathway Commons Protein-Protein Interactions	1.0	null
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-1226-SM-3NMA5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47763
BRD-K76718418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05582
IGR-1	GDSC Cell Line Gene Expression Profiles	1.0	1.65131
GSE77108_4_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6325-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_CH12.LX_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A30437061_Camptothecin_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ABL1_mutant_179_GSE45452	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.94015
RFX5	ENCODE Transcription Factor Targets	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
GSS	DepMap CRISPR Gene Dependency	1.0	3.38486
GSE201309_4_v_6_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE96641_3_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DF-00-BU08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.438702
GSE142210_11_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
cortex of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63334
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.49899
GSE139239_1_v_5_ddr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4227906-pr5002466_si_003.xlsx-LPS-Unnamed_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN012_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.69362
496100453_HIP_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.06291
JUN	ENCODE Transcription Factor Targets	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WV-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HNF1A-27111144-CD8+TCELLS-MOUSE-BLOOD-LYMPHOMA	ChEA Transcription Factor Targets 2022	1.0	null
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.862372
CHD2	ENCODE Transcription Factor Targets	1.0	null
BRD-K48501991	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01209
TAF1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.885534
Dexrazoxane	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.26
GSE118077_4_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
WC-16-IR43_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.22194
clemizole-2301	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
LMO2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN017_MCF10A.TP53.M_24H:G11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.24009
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE247159_8_v_3_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K83667863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4287
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
coronary artery disease	GWASdb SNP-Phenotype Associations	1.0	0.855449
BRCA1	ENCODE Transcription Factor Targets	1.0	null
HDAC1	ENCODE Transcription Factor Targets	1.0	null
baclofen-1952	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
dorsolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.60685
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A02481876_Importazole_HCC515_24.0_h_60.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K54593730	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06052
GTEX-T2IS-0011-R11A-SM-32QPC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.37047
BRD-K09842906	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32173
hsa-miR-4694-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
acebutolol-1493	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XPVG-0326-SM-4B653	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838656
flufenamic acid-5478	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.94368
GSE135030_11_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6977700-aging-12-102667-s006..xlsx-Sheet1-The_identified_1173_dysregulated_LmiRM-CTs_in_MI_using_our_method_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
CTNNBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30021
COR-L26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.16758
GSE206729_2_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE226249_5_v_4_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
dipyridamole-1517	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
LIVF001-021	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0271
BRD-K24076516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09518
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
STAT3	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5483-11A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE120370_0_v_3_thrombin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9794594-DataSheet_1.xlsx-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Fat-macrophage	Tabula Sapiens Gene-Cell Associations	1.0	6.06306
GSE135352_0_v_3_napabucasin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GABPA_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCL-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
0179445-0000-4292	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
LM-1685-253	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
JURKAT, CLONE E6-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A13J-11A-13R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1207-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4505	TargetScan Predicted Conserved microRNA Targets	1.0	0.389112
496100407_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.41633
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.92273
GSE254155_1_v_0_per2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K52532740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68893
GSE156033_1_v_2_sparc_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11109217-41420_2024_2017_MOESM3_ESM.xlsx-Fig_4H_TAF2-bound_genes-Tag_dentsity_of_TBP_ChIP-seq_signal_for_TAF2-bound_genes_in_Fig_4H_TBP	Rummagene Transcription Factor Associations 2026	1.0	null
201T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K56761719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0762
cuneus, left, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16259
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
artery disease	GWASdb SNP-Disease Associations	1.0	0.134091
TAL1_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VMRCRCW_KIDNEY	CCLE Cell Line Proteomics	1.0	6.05212
GSE80819_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CPLANE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2869
GTEX-PVOW-0008-SM-48TE8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961125
pallidal septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17175
SMC3-22415368-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XGQ4-0326-SM-4GIEE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.978097
CTCF_fibroblast of pulmonary artery_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG8-2426-SM-3GILL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38526
EBC1	CCLE Cell Line Gene CNV Profiles	1.0	2.24141
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.959632
CD2AP	Pathway Commons Protein-Protein Interactions	1.0	null
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NIHOVCAR3_OVARY	CCLE Cell Line Proteomics	1.0	2.81371
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33716
BRD-K79433629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07164
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.0122
GTEX-SUCS-1626-SM-32PLS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02635
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE254155_5_v_0_per2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NFE2L3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00533057
LC-12-VN85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.315885
outer SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.895454
sulfinpyrazone-3192	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CSTF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69405
BRD-K25176380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26788
GSE149903_0_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11627398-pone.0315219.s005.xlsx-MTF1-symbol_MTF1	Rummagene Transcription Factor Associations 2026	1.0	null
DM3	CCLE Cell Line Gene Expression Profiles	1.0	1.61617
PMC9314667-Table_1.xlsx-Regulons-SOX10_SOX10	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE140200_1_v_0_trim59_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE226249_0_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9698
GTEX-U3ZM-1226-SM-3DB9G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16003
Brain Lower Grade Glioma_LGG_TCGA-E1-5322-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dexamethasone_homo sapiens_gpl6480_gds3946	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DCTN3	Pathway Commons Protein-Protein Interactions	1.0	null
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32386
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CBX3_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.742
FE-64-KC49_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.498545
GPRC5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12946
Ebolavirus(ZEBOV)_3day_Spleen_None_GSE57214	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.40106
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
tolfenamic acid-6354	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HNF4	MotifMap Predicted Transcription Factor Targets	1.0	null
17880687-TableS2	GeneSigDB Published Gene Signatures	1.0	null
PMC5819186-13040_2018_163_MOESM3_ESM.xlsx-Lung-TCF21_TCF21	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04163
BRD-A74615450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07122
abnormality of the coronary arteries	GWASdb SNP-Phenotype Associations	1.0	0.324368
H3K4me1_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GT-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE114258_1_v_2_foxk1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.06771
ethisterone-2326	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.40827
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1103
GSE184892_7_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A05883068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02983
CRCGN015_MCF10A_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.10385
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-8596-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K16717067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.47942
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29156
GSE201217_4_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
piribedil-5434	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE244518,GSE244520_1_v_0_dnmt3b_human	RummaGEO Gene Perturbation Signatures	1.0	null
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FD-91-OK66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.744714
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CORL23	DepMap CRISPR Gene Dependency	1.0	2.6883
6-bromoindirubin-3'-oxime-6559	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KYSE-510	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.839157
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.5636
metronidazole-1921	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE184892_6_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K73942403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40041
diclofenac-445	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
alfadolone-6506	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-Q2AG-0426-SM-2S1PU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1157
Perturb_15212_KO_Ifnar1_ERP120505	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
LA-42-ER00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.047
GTEX-XQ8I-0126-SM-4BOPL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.905109
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57455
CRCGN015_HEPG2_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.64415
TAF1_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE190534,GSE190536_0_v_3_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K46121327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16732
SOX11-23321250-Z138-A519-JVM2-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE113106_2_v_5_dnm2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01293
GTEX-QVUS-0226-SM-3GIJY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.957426
GSE234043_0_v_1_abcb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ritodrine-2635	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.835204
SA1-22415368-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7839
CEBPD	ENCODE Transcription Factor Targets	1.0	null
TCF21-26020271-SMOOTH-MUSCLE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17226
EW-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.65881
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.72837
TAF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CD8_Naive_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.872078
BT474	CCLE Cell Line Gene Expression Profiles	-1.0	-2.2041
oxprenolol-5871	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
skin_5f	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.840398
t70-white-adipose_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.73335
GSE119694_1_v_0_lifr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AC-76-JB92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.209769
MCAS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.20256
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AK5ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain - Frontal Cortex (BA9)	GTEx Tissue Gene Expression Profiles 2023	1.0	5.17361
GSE184087_2_v_1_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K36583698	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35166
BRD-K62909525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16225
GSE213228_1_v_3_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K71574401	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38685
MIA PACA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0524
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE152050,GSE152052_1_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K85722065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68725
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4904359-12915_2016_267_MOESM12_ESM.xlsx-TPRX1_DOWN-All_significantly_up_regulated_genes_determined_by_DESeq2_fold_change_greater_than_1_25_going_down_from_an_FPKM_of_at_least_2_TPRX1	Rummagene Transcription Factor Associations 2026	1.0	null
griseofulvin-2293	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cell	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
NCIH2196	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52075
CTCF_foreskin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146156_2_v_3_tagap_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.908414
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VF-01A-31R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
doxycycline-7195	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE174522_1_v_0_spp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K22797212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33645
Lung squamous cell carcinoma_LUSC_TCGA-51-4081-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23495
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U4B1-0526-SM-4DXTK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38279
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
BRD-K07706477	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27039
GSE147210_2_v_5_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE246660_1_v_0_glycerol_human	RummaGEO Drug Perturbation Signatures	1.0	null
MXI1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAL1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE128634,GSE128636_4_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A49680073_Cucurbitacin I_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE166169_2_v_3_elp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H4K20me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_BE2C_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0725
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.998259
hsa-miR-486-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
CEBPB_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K31721388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.215
BRD-K15647573	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16584
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.17552
GSE140651,GSE140653_2_v_1_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69027
BRD-K78007953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68792
MM160113	DepMap CRISPR Gene Dependency	1.0	2.08691
TAL1_megakaryocyte_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12865_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.58904
Bonemarrow	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.16042
BRD-K03852663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23536
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PMC12753515-Table2.XLSX-G5-specific_down_only_top_500-EGR2_EGR2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-NR2F2_NR2F2	Rummagene Transcription Factor Associations 2026	1.0	null
tolfenamic acid-5454	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
atractyloside-7393	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58138
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7433-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-UE-A6QU-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K93662118	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00514
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE57871_6_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.18716
GSE250534_0_v_3_cabergoline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE210580_5_v_6_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
procaine-6329	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE137144_2_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TKQ1-1426-SM-4GICK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42932
CRCGN010_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1326
GSE184892_7_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
CAL-51	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.27299
BRD-K45037973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11259
fenbufen-3618	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN015_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.97224
GSE93124_0_v_1_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
mesoridazine-2874	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE89018_12_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
depudecin-982	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TAL1	ENCODE Transcription Factor Targets	1.0	null
GSE205163,GSE205164_1_v_0_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.07769
GTEX-WL46-0011-R11A-SM-3MJFT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33821
Perturb_14796_OE_Mycn_SRP094656	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.64998
Cytoplasmic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
KB-46-EJ60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24567
H3K27ac_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Culmen	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44277
medial mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3873
guanabenz-1961	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
trioxysalen-5736	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
r7 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44853
HCC2998	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.09949
Prestwick-642-2815	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ficolin-1-rich granule membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.348
GSE106170_1_v_0_nap1l3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE179974_3_v_4_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
carbimazole-3299	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_GM12865_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5045
SU-DHL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25931
intracellular membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GABPA	ENCODE Transcription Factor Targets	1.0	null
KCI-MOH1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.903944
cyclopenthiazide-4229	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
isopropamide iodide-7133	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_17637_OE_KLF4_SRP094697	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
NLGN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80184
GTEX-XOTO-0011-R11B-SM-4B64O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65354
posterior part of anterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45156
JHOS2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.86404
citalopram-4555	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN015_HEPG2_48H:H04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.12543
facial motor nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.81753
PECAPJ34CLONEC12	CCLE Cell Line Gene CNV Profiles	1.0	1.45456
GSE225656_0_v_1_tsc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bed nuclei of the stria terminalis, anterior division, rhomboid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72362
CRCGN008_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.5848
GTEX-XBEC-1526-SM-4AT68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.867069
GSE94011_0_v_3_pias3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TCF12_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2108
striatum_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.67325
LIVF001-005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0298
hydroflumethiazide-7019	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
nitrofurantoin-2303	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NR2C2AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.19271
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47924
PC-62-AQ92_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.314548
Mafb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.4009
C6orf62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22128
naloxone-4645	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TCF7L2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.91321
CTCF_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RM2N-1626-SM-2TF5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06954
PMC12337709-mmc3.xlsx-Wild-type_vs_RAG1_KO_spleen-Unnamed_1_RAG1	Rummagene Transcription Factor Associations 2026	1.0	null
sirolimus_homo sapiens_gpl2895_gse16944	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36401
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00476
Lobules IV-V, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44703
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89733
GSE114992,GSE114993_1_v_11_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cotinine-1929	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
pyridoxine-2751	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
AC-36-TL21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.280364
Sarcoma_SARC_TCGA-DX-A3LY-01B-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZC3H11A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LM-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE109913_1_v_2_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN012_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.12894
ONS76	CCLE Cell Line Gene CNV Profiles	-1.0	-1.82467
SJCRH30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.875751
BRD-K25387295	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61221
GTEX-XXEK-1126-SM-4BRUX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28765
GSE214505_0_v_1_akr1b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZMIZ1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsal part of m1A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.8229
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RA-27-ST16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.316284
Central lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10265
SPI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.98375
BRD-K76551930	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45362
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BE-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH3255	CCLE Cell Line Gene Expression Profiles	-1.0	-1.83008
cefoxitin-3477	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SIRT3_KO_GDS4058_454_mouse_BROWN ADIPOSE TISSUE	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
layer II of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.944117
GSE210101,GSE210114_5_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0274
GSE180200,GSE180201_3_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CHD4-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
nucleus	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
terguride-5400	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE213588_10_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE137144_5_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
scopolamine N-oxide-6335	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-R55E-0526-SM-2TC6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.8378
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.72878
GSE193258,GSE193259_9_v_12_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5024
PD-70-VS77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.255242
GSE171712_0_v_1_scgb1a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.59177
GTEX-T6MN-0526-SM-32PMS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44088
hsa-miR-3619-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
RBPJ	ChEA Transcription Factor Targets	1.0	null
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAL1_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
tRNA-intron endonuclease complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.73
UBF1/2-26484160-CHIP-SEQ-HMECS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE140997_2_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35516
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34042
GATA1_G1E-ER4_mm9_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE195559_2_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.891
GSE236003_1_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
fertilizedegg	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.888122
GTEX-S7PM-0526-SM-3NM92	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50143
GSE186044_4_v_2_tcra_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE196259_2_v_3_gcm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE221327_8_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SIU8-0526-SM-2XCDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57201
Declive (VI)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68488
SLC45A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1119
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01383
BRD-K27888332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39917
GSE157592_1_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18646
BD-18-MM33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.483721
CRCGN017_MCF10A.WT.HP_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3422
GTEX-OXRL-1626-SM-2YUMU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.25066
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:J01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.84575
piroxicam-2252	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
dextromethorphan-6300	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54697
RAPA_EARLY_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
FD-59-TC81_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.259578
posterior tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29577
BRD-K24598235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02794
GSE149903_6_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
verapamil-1927	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00211
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A5KG-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE213588_10_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K63271817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62149
GSE77108_0_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
salivarygland_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.913519
trichostatin A-5935	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K22475995	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42605
salivarygland	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.06081
BRD-K94493764_NP-009169_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K46715415	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.49132
GSE100316_3_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TIG3TD	CCLE Cell Line Gene Expression Profiles	1.0	1.38062
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PSS008	DepMap CRISPR Gene Dependency	1.0	2.62866
GSE112860_0_v_2_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
amphotericin B-6303	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Sarcoma_SARC_TCGA-DX-A3LU-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DBTRG05MG	DepMap CRISPR Gene Dependency	1.0	2.90541
GSE63048_11_v_12_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146982_7_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.850643
Primary somatosensory area, lower limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17432
Prostate adenocarcinoma_PRAD_TCGA-KK-A8I4-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149943_1_v_0_cd8a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WHPG-2226-SM-3NMBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14356
demecarium bromide-2773	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE235066_7_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
RPMI-7951	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.48997
PPARG	ChEA Transcription Factor Targets	1.0	null
GSE113221,GSE113968_6_v_1_prdm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169152_3_v_2_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
brownfat	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.21949
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20N-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lobule III, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22648
cytoplasmic part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE189336_1_v_0_nitric oxide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE117212,GSE117214_0_v_1_zbtb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BD-69-GX17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.562752
periventricular stratum of r7Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44656
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15977
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4376
macrophage	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7209
BB-86-BE19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.761572
SNU201	CCLE Cell Line Gene Expression Profiles	1.0	1.39906
GSE231799_2_v_1_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.940873
H3K27ac_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AARD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25624
lateral orbital frontal cortex (area 12/47)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.88025
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.72503
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PSDG-1526-SM-48TCY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.977265
BRD-K14990409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30918
GSE171175,GSE171181_1_v_0_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
SF3B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77428
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.94849
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3BM-11A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67O-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BHLHE40_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21176
CTCF_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.42212
BRD-K29469525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00767
GSE247862,GSE247863_4_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE111247_2_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GCFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18984
Ventral pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.926266
brinzolamide-5016	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15577
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27679
GTEX-WFON-1226-SM-3TW8F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837432
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	1.0	2.0929
GSE121824,GSE121826_0_v_2_scaf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
MED21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68839
CRCGN011_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22125
GTEX-S4Z8-1826-SM-3K2BH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03822
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0661
PMC7397849-supp_gad.338681.120_Supplemental_Table_S2.xlsx-S2B_in_vivo_shared-Suppl_Table_S2B_shared_genes_between_RCAS-YAP1-MAMLD1-dR3R1_RCAS-YAP1-FAM118B_RCAS-YAP1-TFE3_in_vivo_tumors_RCAS_mouse_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
fluocinonide-3933	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC9980149-media-17.xlsx-Supp_Table_12_Bulk_Seq_CTH_KD_I-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14108
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE110178_1_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
deoxynivalenol	CTD Gene-Chemical Interactions	1.0	null
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.32941
practolol-4603	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE213588_8_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE140937,GSE140938_1_v_2_slfn11_human	RummaGEO Gene Perturbation Signatures	1.0	null
PATU8988S	DepMap CRISPR Gene Dependency	1.0	2.96434
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2170	GDSC Cell Line Gene Expression Profiles	-1.0	-1.46239
COPS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45468
GATA2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE181517_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE210101,GSE210114_7_v_9_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
CA-68-KG29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.214967
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
AA-62-OC45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.276609
microcellular tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72111
GTEX-SSA3-0326-SM-32QPS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.974012
PMC6347712-pnas.1812449116.sd06.xlsx-iPSC_IRF7_48h_rest_RNAExpress-Gene_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
Pyramus (VIII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01805
GTEX-P44H-0011-R11A-SM-2XCER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22308
MAFF	ENCODE Transcription Factor Targets	1.0	null
GTEX-WFON-0326-SM-3GIKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901478
NFYA	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-4753-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.017945
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A24714998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03213
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7590-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
PMC5059470-ncomms12992-s6.xlsx-CRS-NOCRS-Supplementary_Data_5_Integration_Frequency_in_cirrhotic_CRS_and_non-cirrhotic_no-CRS_Tumor_Samples_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
SLC35A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01378
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6087-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
17952126-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-POMQ-1926-SM-3NB1Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19658
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Inclusion Body Myositides_Muscle tissue_GSE3112	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.74554
hsa-miR-30a	TargetScan Predicted Conserved microRNA Targets	1.0	0.115091
GSE71529,GSE71558_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
r9 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08301
GSE240027,GSE240030_5_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
levopropoxyphene-5503	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE158815_5_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
butamben-6093	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE62843,GSE64371_4_v_0_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
streptozocin-5836	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE211128_4_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11773
CTCF_CH12.LX_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE77108_0_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KA-81-AG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.711587
GTEX-T6MN-0826-SM-32PM4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917458
Perturb_12891_KD_Setd2_SRP035252	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.0322
GSE228413_0_v_1_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
External side of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.521
17616640-TableS1	GeneSigDB Published Gene Signatures	1.0	null
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.23548
GSE147662_2_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE184210_0_v_3_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
cefalexin-5615	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE166315_2_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HCC1806	CCLE Cell Line Gene CNV Profiles	-1.0	-2.4568
SP4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
velnacrine-3292	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE218580_1_v_2_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BX-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K41305193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00435
BRD-K25905181	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18299
GTEX-R53T-1826-SM-3GIJX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.97933
Secretory granule	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE88819_3_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
superficial stratum of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.50051
Lung adenocarcinoma_LUAD_TCGA-44-6777-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1568	CCLE Cell Line Gene CNV Profiles	1.0	1.46979
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMD1-0011-R11A-SM-4AT5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.92628
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32508
finasteride-4766	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
erastin-6412	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21777
CRCGN015_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7282
BRD-K31834149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07614
GSE146982_7_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Membrane	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.555
Liver hepatocellular carcinoma_LIHC_TCGA-YA-A8S7-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Muscle-endothelial cell of vascular tree	Tabula Sapiens Gene-Cell Associations	1.0	1.27584
PMC9576445-IJG2022-9264555.nxml--Potential_targets_of_hsa-miR-15b-5p_AND_hsa-miR-184_NOT_hsa-miR-16-5p_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RBBP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70245
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN013_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6751
GSE104508_2_v_3_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
midecamycin-2026	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE169571_3_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH2081	CCLE Cell Line Gene Expression Profiles	-1.0	-1.98406
GSE148200_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNHIT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2455
BRD-K29760532	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99235
primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.42599
GSE196699_4_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE228894_3_v_2_rnmt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SCL-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE192663_1_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE226091,GSE226092_0_v_1_sall1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.8204
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26396
ZEB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NRF1	ENCODE Transcription Factor Targets	1.0	null
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.971449
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
leukocyte apoptotic process	GO Biological Process Annotations 2025	1.0	null
LMO2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4469	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
mantle zone of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05745
GSE210580_5_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U412-0326-SM-3DB9L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877613
GSE169571_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE229914_2_v_3_keap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
u26684	HPA Cell Line Gene Expression Profiles	1.0	1.26482
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17337
RUNX1-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03553
GTEX-PX3G-0006-SM-33HBQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11634
SZRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1843
HS888T	CCLE Cell Line Gene Expression Profiles	1.0	1.38837
MYC	ENCODE Transcription Factor Targets	1.0	null
AURKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19399
EF-74-KW12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.28372
GSE229671,GSE229673_2_v_1_yrdc_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.279
hsa-miR-1304	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
FF-86-NH56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.251489
inferior occipital gyrus, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.856936
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE152441,GSE152442_0_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0479
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02193
GATA3-21878914-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE144231_2_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ACTR1A	Pathway Commons Protein-Protein Interactions	1.0	null
diflunisal-1990	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5978-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1845
GSE99875_2_v_0_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A.WT.HP_24H:K18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.63048
H4K20me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KP-N-RT-BM-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.27773
FF-06-MO73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.841702
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.12737
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9394
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE165548_2_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
FAHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00272
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE230329_0_v_3_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2AphosphoS5_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5939-11A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QLQW-1326-SM-2S1QS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.893059
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.45903
praziquantel-3189	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TTNPB-451	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834106
GSE111247_2_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
agranular insular cortex (area Iag)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.52359
CRCGN015_MCF10A.TP53.M_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.8357
dyclonine-7261	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-S4P3-0008-SM-3NM8R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19346
BRD-K49215099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64059
SPI1	ChEA Transcription Factor Targets	1.0	null
GTEX-SN8G-0326-SM-32PLG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15492
GSE205556_1_v_0_bexarotene_human	RummaGEO Drug Perturbation Signatures	-1.0	null
inferior olivary complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.969958
GSE210101,GSE210114_7_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
CHD7	ENCODE Transcription Factor Targets	1.0	null
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09923
idazoxan-6465	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GABPA_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE240027,GSE240030_1_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
lactobionic acid-6605	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Prestwick-983-6520	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
18245496-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.85645
LIVF001-008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81913
GSE149366_1_v_0_sulconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
SETDB1-19884257-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69854
GATA2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ZNF714	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01054
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5559-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8716
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K56032186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11062
BRD-A89499670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12344
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
spleen_3b	HPA Tissue Sample Gene Expression Profiles	1.0	1.8362
GSE239844_6_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
loperamide-5267	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
(+)-isoprenaline-3384	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GATA3-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Liver	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KMT2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47757
MG-262-7079	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE230573_1_v_0_dcaf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
trovafloxacin_homo sapiens_gpl96_gse9166	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE202434,GSE202438_8_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung-non-classical monocyte	Tabula Sapiens Gene-Cell Associations	1.0	0.46166
HEK 293T	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.919326
isocorydine-6843	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE146072_0_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-UJMC-1826-SM-3GADT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.49299
GSE86507,GSE86509_7_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K80766355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08531
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.76318
GTEX-OOBJ-1026-SM-3NB2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.76998
GTEX-TKQ2-0826-SM-33HB6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58778
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
salbutamol-7376	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H1568	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Artery - Aorta	GTEx Tissue Gene Expression Profiles 2023	1.0	1.43822
CRCGN015_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.29258
SIRT6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCFC1	ENCODE Transcription Factor Targets	1.0	null
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47761
coralyne-2652	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K85977570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55179
GSE140646_0_v_1_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.2007
NPAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21727
Plagl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.9987
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1142
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE254517_2_v_0_irf7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-761	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
HEY	DepMap CRISPR Gene Dependency	1.0	7.96658
hsa-miR-30d	TargetScan Predicted Conserved microRNA Targets	1.0	0.115091
periventricular stratum of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41394
SCA7_Knock-in_GDS3545_560_mouse_Cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
estradiol-5601	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
tanespimycin-450	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WH7G-1126-SM-3NMBK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10268
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.845589
BRD-K45400577	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35953
BRD-K61505971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1218
GSE122215,GSE122217_0_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
diprophylline-1811	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6843
Hemispheric regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54605
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JH-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE142210_4_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XMK1-0126-SM-4B65F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4865
atropine oxide-6812	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-OIZI-0005-SM-2XCED	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923151
Anteromedial nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27041
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6V1-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MECOM	ChEA Transcription Factor Targets	1.0	null
PMC6744561-41467_2019_12125_MOESM7_ESM.xlsx-BRCA1_448_TCF7_rep1_sorted_peak-Gene_Name_TCF7	Rummagene Transcription Factor Associations 2026	1.0	null
STAT5A	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-1909	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
VZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.86863
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_16665_KO_Slc27a2_SRP186493	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.72606
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68776
GTEX-RVPU-2426-SM-2XCAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23615
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6131-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRCA1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NDUFB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26284
GSE196671_5_v_1_obox4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Retrosplenial area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0378
PML_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dms79	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.953
BRD-K60661821	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07553
TAL1_erythroblast_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K04701596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.64881
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K28021686	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07353
ZNF830	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07425
GA-28-SS67_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.387911
HH	CCLE Cell Line Gene CNV Profiles	-1.0	-2.97797
CTCF_GM20000_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Prestwick-981-7464	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
guanabenz-5703	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-QDT8-0006-SM-32PL3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12587
spleen	HPA Tissue Gene Expression Profiles	1.0	1.67848
liver	GTEx Tissue Gene Expression Profiles	-1.0	-1.01862
Lung squamous cell carcinoma_LUSC_TCGA-43-6773-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE213588_8_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U4B1-1626-SM-3DB8N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32785
CTCF_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPARG-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE205316,GSE205317_2_v_1_nrip1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K63547380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47238
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18277
DMS153	CCLE Cell Line Gene CNV Profiles	-1.0	-2.11416
GSE88819_5_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
flupentixol-2643	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
diphenylpyraline-4765	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K9ac_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
amitriptyline-5453	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE210101,GSE210114_1_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE73561,GSE73563_0_v_1_mef2c_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K76065617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12568
ELF1	ENCODE Transcription Factor Targets	1.0	null
Edinger-Westphal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.974247
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K42108985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13202
A172	BioGPS Cell Line Gene Expression Profiles	1.0	1.16492
NCI H322M	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.842761
PMC6930440-jcav11p0520s3.xlsx-MI_vs_FG-Unnamed_0_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Rectum adenocarcinoma_READ_TCGA-F5-6465-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE44157,GSE44163_1_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
thyroid gland	HPA Tissue Protein Expression Profiles	1.0	1.28518
GSE210580_4_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NFYB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE223008_6_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12369
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.82533
rilmenidine-6512	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
megestrol-6468	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Anteroventral periventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31194
ELF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DCTN1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QLQ7-1726-SM-2S1QQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917319
GSE109285_3_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE96641_3_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6481-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LD-69-ZV56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.500292
ZNF143	ENCODE Transcription Factor Targets	1.0	null
BRD-K36271521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1264
PRKACB_knockdown_91_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.04237
POLR2AphosphoS2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8945
ERO1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02799
IKZF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02817
propafenone-2871	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.043246
BAS-012416453-6908	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POU2AF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62594
TAF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE247862,GSE247863_0_v_5_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GA-28-SS67_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.626229
GTEX-S4Q7-0526-SM-4AD5N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9882
tetrandrine-6082	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.086
GSE146074_9_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:A21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12314
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.62424
FLI1_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE144231_4_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE65617_5_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MEIS1	ChEA Transcription Factor Targets	1.0	null
NCIH211	CCLE Cell Line Gene CNV Profiles	-1.0	-1.66227
COLO-800	GDSC Cell Line Gene Expression Profiles	1.0	1.77523
GSE143830_0_v_1_trex1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE87615_0_v_3_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE242290_3_v_2_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7927886-2019_239970_BOUSSAID_SUPPL_TABS2.xlsx-GATA1_targets_-_genesets-Unnamed_3_GATA1	Rummagene Transcription Factor Associations 2026	1.0	null
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0482
GTEX-S32W-2126-SM-2XCB1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02785
SPI1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XK95-0008-SM-4AT5G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09293
Prostate adenocarcinoma_PRAD_TCGA-EJ-7314-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EGR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE159446,GSE159449_1_v_0_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE188814,GSE188854_0_v_1_wtap_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GATA1_G1E-ER4_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE135350_3_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1465
GSE172458_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.3417
GSE171837_0_v_3_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K87666020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20979
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KA-29-AB08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.466883
IFT46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09324
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCFC1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.21996
tridihexethyl-5486	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KAT2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE150049_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SOX11	ChEA Transcription Factor Targets	1.0	null
CTCF_GM12872_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1	ENCODE Transcription Factor Targets	1.0	null
superficial stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3725
CRCGN016_MCF10A.WT.HP_24H:A18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.65688
prenylamine-5489	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CVB3_3Hour-Infection_None_GSE697	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.96374
anabasine-6074	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7972
mecamylamine-7263	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
LAMA-84	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE132386_1_v_0_ppara_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE200352_5_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T5JC-0011-R11A-SM-32PMB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00589
GTEX-O5YW-0326-SM-2I5EI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.974504
GSE185519_4_v_7_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5763-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE73628_8_v_2_igf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q7-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.91388
inner SZ in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.880861
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6478-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K27997230	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13814
EE-03-SG02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.598529
oculomotor nuclear complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.81626
Perturb_2008_KO_Arid1a_SRP182831	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.1462
PMC11067031-pnas.2317690121.sd03.xlsx-gene_list_-_2022-04-13T081711_1-Differentially_expressed_genes_between_PML_RARA_GFP_vs_Empty_vector_GFP_mouse_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE211128_2_v_1_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0008-SM-4DM6A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983191
Prostate adenocarcinoma_PRAD_TCGA-EJ-7123-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCMV_24Hour-Infection+PP2_21084488_GSE24238	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.30954
BRD-K38189984	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1409
WE-48-PP43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215742
Pancreas-myeloid cell	Tabula Sapiens Gene-Cell Associations	1.0	4.02762
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUR-01A-21R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11696420-41467_2024_55617_MOESM3_ESM.xlsx-Sheet1-Supplementary_Data_1_The_2495_differentially_expressed_genes_between_the_L3MBTL3_knockout_L3-KO4_or_L3-KO5_and_control_C_groups_of_SUM159PT_cells_L3MBTL3	Rummagene Transcription Factor Associations 2026	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.877472
dorsal thalamus_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.894865
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.43789
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.97695
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_upreg-mouse_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6384-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.46163
Rapamycin vs Ctrl_Exp2_MEFs (Mouse) [21659605]	SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Drugs	1.0	null
amoxapine-1931	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H358	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.34725
CRCGN013_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.81279
CRCGN016_MCF10A.WT.HP_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.19275
hsa-miR-138	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0938
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DU-4475	GDSC Cell Line Gene Expression Profiles	-1.0	-2.24152
r10 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73869
epivincamine-6838	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE196699_7_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.3218
AC-30-XU83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.231775
Zfp809	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.2318
organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GSE168797_1_v_0_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Plastid inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.907
GSE247764_5_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.29236
proxyphylline-7290	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE191174_0_v_1_ccdc92_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.01956
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-1184	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
hexetidine-3318	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29694
JD-81-YX02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.249941
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.876015
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PCDHB15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38192
PMC7906903-41366_2020_716_MOESM2_ESM.xlsx-DEG_HMGA2-fusion-Gene_Symbol_HMGA2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K23316938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02305
superficial stratum of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09857
RWDD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06355
GSE202284,GSE202289_3_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE187006_0_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8429-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lambdoid septal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19038
enalapril-7265	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08585
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A5RJ-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pentolonium-2305	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K90475322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14466
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE152441,GSE152442_0_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_foreskin fibroblast_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OF-05-CB18_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.243
H3K9ac_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
delsoline-6075	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DOV13	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59148
GSE261563_9_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BC-10-SB73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.302134
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_K562_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE102598_1_v_2_nmda_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.962498
rostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.975408
GSE217441,GSE217443_1_v_0_ivosidenib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ELF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE206226_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210101,GSE210114_7_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
Nucleus preopticus medianus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.617
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42042
GSE181517_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10350077-media-7.xlsx-Microglia_P_LPS_All_Up_GO-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.96383
LS_90min_LPS vs ctrl_RAW264.7_macrophage (Mouse) [20222745]	SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Drugs	1.0	null
BRD-K04652643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23538
GTEX-O5YT-0926-SM-48TDG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99427
enalapril-7428	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.16945
GSE242199_6_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GATA1_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.957663
SIRT6	ENCODE Transcription Factor Targets	1.0	null
TIAM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00611268
m2 part of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.07588
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CD-13-QZ32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.545227
GSE186065_0_v_1_sirt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S3XE-0008-SM-3NM8O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934986
Cytoplasmic vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.852
GSE198165,GSE198166_7_v_4_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
atherosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.324368
CAMSAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09896
ME1	CCLE Cell Line Gene Expression Profiles	1.0	1.53172
BRD-K23535862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07991
BRD-K95369587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03888
CRCGN016_MCF10A.TP53.M_24H:A19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.61058
CTCF_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2484
GTEX-PW2O-0126-SM-48TC8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47296
BRD-K47109712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60068
GTEX-QLQW-0126-SM-447BK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69446
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QV31-1426-SM-2S1QD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.20096
hsa-miR-4749-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GSE118794_5_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
U118MG	DepMap CRISPR Gene Dependency	1.0	2.16121
umbilicalcord	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.895033
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
COLO800	CCLE Cell Line Gene Expression Profiles	1.0	1.89996
vascular disease	GWASdb SNP-Disease Associations	1.0	0.096621
oxolinic acid-2103	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.0549
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39402
GSE197571_2_v_1_foxm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Prestwick-685-6043	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Medial preoptic nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7445
GSE244710_1_v_2_srsf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K86268010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57573
abamectin-5864	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KP1N	DepMap CRISPR Gene Dependency	1.0	2.20239
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.9021
FXR	MotifMap Predicted Transcription Factor Targets	1.0	null
PMC11502753-41467_2024_53330_MOESM11_ESM.xlsx-Sheet1-SMAD3_target_genes_hES_SMAD3	Rummagene Transcription Factor Associations 2026	1.0	null
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.871207
GSE148252_1_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POU2F2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100327_PCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.09591
CTCF_GM12870_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYSE180_OESOPHAGUS	CCLE Cell Line Proteomics	1.0	2.02789
ketotifen-5842	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-P78B-0008-SM-48TE1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46831
PMC8045971-Table_3.xlsx-vs_LPS_ctrl-Unnamed_4_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
MYC_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WY7C-2526-SM-3NB2N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64937
GABPA_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_3414_OE_Zeb2_SRP072845	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.51518
primary motor cortex (area M1, area 4)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.866615
AC-55-XA97_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.434532
captopril-1907	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A6-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AB-68-SC09_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.238602
CD-35-BD44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.266539
BRD-K00773626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06539
PMC11575453-12964_2024_1940_MOESM1_ESM.xlsx-S2_NKL_PP-Gene_GLIS2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE246660_1_v_0_lmo3_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.87034
medial portion of the shell	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01027
GSE248045,GSE248046_0_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PSMA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1513
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04837
GSE228181_4_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Posterior parietal association areas, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3725
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.934014
GSE158715_2_v_4_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6943-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.TP53.M_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.3947
BRD-K35133923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02349
ALAS2_OE_GDS2118_74_human_Blood	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE210662_2_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	1.0	null
DA-85-SU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.221345
CTCF_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AKT1_knockout_211_GSE39699	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.75576
496100496_FWM_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.25636
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.22909
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC12396377-jcb_202307079_tables1.xlsx-Fig_1C_i_-_iii_left-x_TFEB_KO_con_VS_WT_con_DOWN_TFEB	Rummagene Transcription Factor Associations 2026	1.0	null
estradiol-5205	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
OC-10-FB51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.275053
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07305
Nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06411
BRD-K63970901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15099
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6YC-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
leukocyte apoptotic process	GO Biological Process Annotations 2023	1.0	null
ME-31-RM40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.90594
GSE226249_0_v_4_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K68364310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41965
GSE147943_5_v_1_cited2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE77108_8_v_9_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
sulfadimidine-3940	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FA-36-VA24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.740844
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15864
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BS-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8047323-Table_2.xlsx-LPS_PMMA_T24-GeneSymbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CORL279	DepMap CRISPR Gene Dependency	1.0	2.61282
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
PSMB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11661
MBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54111
GSE108326_1_v_0_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMARCB1	ENCODE Transcription Factor Targets	1.0	null
UACC257	CCLE Cell Line Gene Expression Profiles	1.0	1.77127
STAT3-18555785-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
tretinoin-5571	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Bed nuclei of the stria terminalis, anterior division, juxtacapsular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51784
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.8453
SG in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.96945
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3426-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
17880687-TableS3	GeneSigDB Published Gene Signatures	1.0	null
ELF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBP_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1207-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.078844
hsa-miR-3173-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE98831_1_v_0_brca1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
sulfametoxydiazine-5732	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SIN3A_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213588_10_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE213588_10_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GABPA_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K48780709	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56208
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_3hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE103068_0_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
dorsomedial hypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04722
PHA-00665752-6578	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC4407272-elife06857s001.xls-MITF_partners_CAF-MITF_partners_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-1913	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
KP4	CCLE Cell Line Gene CNV Profiles	1.0	1.86587
hesperetin-1947	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.92273
orbital frontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.42766
eGFP-JUNB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.64961
hsa-miR-20b	TargetScan Predicted Conserved microRNA Targets	1.0	0.265648
AE-39-DG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.376126
cytosol	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GSE153341_2_v_3_atf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TCFAP2C-20176728-TROPHOBLAST STEM CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE198165,GSE198166_7_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE152441,GSE152442_6_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE201309_4_v_8_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-4763-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GSE196699_7_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Chloroplast envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.849
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4842-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
imatinib-483	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
outer portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.905909
furaltadone-3838	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
METTL25B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12783
BRD-K88378636_withaferin-a_MCF7_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE196699_2_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17488
ERBB3_knockout_239_GSE32129	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.29077
GTEX-OXRK-0926-SM-2HMKP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0896
prilocaine-3624	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
vinpocetine-3174	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
sulpiride-1887	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K88510285_B675700.cdx_HCC515_24.0_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_11979_KD_Etv5_SRP304972	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Integument	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
hsa-miR-4802-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.145356
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32617
carbenoxolone-4173	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-PWOO-2326-SM-2S1PQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.851192
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Tuberomammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78181
CTCF_cardiac muscle cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
t61-colon_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.05691
TEAD4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:A19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.0614
proguanil-5506	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LC-12-VN85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.749523
santonin-4353	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9980149-media-17.xlsx-Supp_Table_12_Bulk_Seq_CTH_KD_I-SUPPLEMENTARY_TABLE_12_Bulk_RNA-seq_results_of_invasive_fractions_from_GBM43_CTH_knockdwn_vs_GBM43_control_cells_invading_3D_hydrogels_AR	Rummagene Transcription Factor Associations 2026	1.0	null
cingulate gyrus, retrosplenial part, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.53319
GTEX-X638-0326-SM-47JY1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.997449
periventricular stratum of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8587
trimethoprim-2307	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HDMYZ	DepMap CRISPR Gene Dependency	1.0	2.66174
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of villous mesenchyme_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dropropizine-5531	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
withaferin A-3902	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-QDVJ-1926-SM-2S1PJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18568
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE103068_5_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H69	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-605	TargetScan Predicted Conserved microRNA Targets	1.0	0.119151
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	120.727
CRCGN011_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.47625
rhombomere 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2669
BRD-K84118789	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53215
Zic1::Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.5649
HT1197	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65848
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12872_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.9442
acacetin-3942	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5793
BRD-K85232515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15899
ZD-18-MI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.432072
ursolic acid-2067	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
bendroflumethiazide-3758	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.958569
NHLF	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.10118
GSE146074_0_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
methyldopa-5637	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K05465626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17435
Kidney Chromophobe_KICH_TCGA-KO-8405-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBE2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33165
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.60338
PMC10831540-supplementary_table_1.xlsx-DEG_pc-S-EC2-Unnamed_16_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
lateral mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37337
GTEX-U3ZN-0126-SM-4DXUM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77803
asiaticoside-3504	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
mesalazine-7241	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K57271749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53653
PMC4856960-supp_gkv1471_nar-01762-z-2015-File010.xls-Genes_5kb_E2F7_Hyp-gene_name_E2F7	Rummagene Transcription Factor Associations 2026	1.0	null
ficolin-1-rich granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.21
lorglumide-6456	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.90061
NCI-H2342	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4169-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
carbachol-6742	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLEKHG4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64988
GTEX-XAJ8-0126-SM-47JYG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21812
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K68119260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12601
Perturb_9003_KD_synectin_SRP096767	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.9018
GTEX-R53T-0426-SM-48FEM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05919
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.029037
H3K4me1_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
E2F4	ENCODE Transcription Factor Targets	1.0	null
GTEX-W5WG-1926-SM-4KKZK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95442
GSE236262_2_v_1_trim28_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE114992,GSE114993_7_v_11_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.56363
GSE120612_4_v_3_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE213442_1_v_0_kpna2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE201309_5_v_7_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
gfi1b_22201127_amulv_gof_mouse_gpl6246_gds4302	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.180027
Perturb_13442_KD_Taf12_SRP119047	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.94505
CRCGN012_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.58403
ventrolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.15466
Plasma membrane	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.555
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42036
CRCGN009_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.82951
NFYA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.90877
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.870121
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
CRCGN012_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.41503
GTEX-P44H-1126-SM-48TBU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896243
NB7	DepMap CRISPR Gene Dependency	1.0	2.55139
abnormality of the systemic arterial tree	GWASdb SNP-Phenotype Associations	1.0	0.154438
supraoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.36464
BRD-K60861976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17588
GSE157777_1_v_3_foxa3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null