association	dataset	threshold value	standardized value
GSE127790_11_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Endoplasmic reticulum membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
496100393_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.78176
PMC10709143-41556_2023_1271_MOESM7_ESM.xls-PAX7_Re-injury-Target_name_PAX7	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14828
NDUFB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75053
SCGB3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14915
PMC7914369-thnov11p3676s2.xls-BPTF-KOvsCtrl-AccID_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE228181_3_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE101336_1_v_3_decitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE131649_4_v_10_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZBTB24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.0085
TRAF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34183
PLAGL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.1487
SOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64977
GSE127790_11_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2063
Spi1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	325.848
Muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.888
GULP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25546
GSE125862_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PTTG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30054
GSE146982_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Prdm14	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.3118
Lipodystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.485
GARRE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77652
GSE88819_0_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10528072-NIHMS1928302-supplement-5.xlsx-NEUROD1-target_genes-AANAT_NEUROD1	Rummagene Transcription Factor Associations 2026	1.0	null
EIF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19318
Alx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.7952
Internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE158197_2_v_11_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MEF2C_MEF2C	Rummagene Transcription Factor Associations 2026	1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC10515843-media-1.xlsx-Table_7_Diff_loop_genes_E_v_S-Supplementary_Table_7_Genes_that_involve_significant_differential_looping_in_pediatric_primary_B_cell_CTCF_peaks_compared_to_GM12878_CTCF_peaks_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
KANK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09696
GSE132408_1_v_3_tet2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE164463_2_v_1_pax6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE183271_1_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE89018_11_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.348
ZNF16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11649
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.9058
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Nucleoplasmic reticulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.524
Autosomal recessive limb-girdle muscular dystrophy type 2K	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.108
GSE184892_6_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
limb-girdle muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.493
Autosomal recessive limb-girdle muscular dystrophy type 2I	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.096
Autosomal dominant Emery-Dreifuss muscular dystrophy 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.363
HSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14397
GSE217378_2_v_0_lin28b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NEFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4163
King Denborough syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.104
PMC10282096-41467_2023_39038_MOESM4_ESM.xlsx-All_genes_Upregulated-ENSG00000177426_TGIF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210101,GSE210114_6_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Autosomal recessive Emery-Dreifuss muscular dystrophy 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.179
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8454
TXNL4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03721
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9768
SMN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03995
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_1_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
GSE172494_3_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Tenocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.602
PMC8567138-Table_2.xlsx-Sheet1-IGFBP5_AND_IGFBP7_NOT_IGFBP3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE119978,GSE180930_6_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0346
Nuclear inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.993
GSE234289_5_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146962_0_v_1_glucosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE247084,GSE247087_0_v_1_cdyl_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE173201_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE81803,GSE81912_4_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
X-linked Emery-Dreifuss muscular dystrophy 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.59
ELK4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0627
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9569
Brain - Substantia nigra	GTEx Tissue Gene Expression Profiles 2023	1.0	3.19866
GSE249146_2_v_3_dusp6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Autosomal dominant Emery-Dreifuss muscular dystrophy 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.417
Bach1::Mafk	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.386
PEX14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97853
Tibialis anterior	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.393
PPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57542
GSE224004,GSE224005_0_v_1_chd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE169152_3_v_4_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.108
ARMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04676
GSE128844_0_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE220058,GSE220059_0_v_1_prrc2b_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE130396_1_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CUL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43245
GSE120612_7_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
C2C12 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.859
GSE74251_2_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32714
CENPJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37534
GSE102505_5_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Olig2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.7292
LYSET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15272
NID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22924
EIF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38959
Developmental disorder of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.18
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE200673,GSE200691_2_v_0_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ISL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06573
RBCK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66875
LHX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03187
TBC1D24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55832
GSE234289_4_v_1_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE242367_1_v_0_dpp9_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE147662_2_v_5_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202434,GSE202438_15_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Autosomal recessive limb-girdle muscular dystrophy type 2Q	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.183
GSE127790_4_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Fibroblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.249
GSE193999,GSE194000_4_v_0_atf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE152699,GSE152723_0_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF493	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57712
PTDSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32779
TMEM125	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.896
PMC6078963-41467_2018_5311_MOESM5_ESM.xlsx-48h_KD_UP_Vs_ATAC-z_e_o_To_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CLOCK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9737
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3225
TMEFF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69929
GSE146865,GSE146866_1_v_0_saracatinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE234289_4_v_0_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EFTUD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52583
GSE217405_0_v_1_osimertinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PCDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06099
Attention deficit hyperactivity disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.18
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8088
Synaptic vesicle protein transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.012
CD164L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12696
WDR55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19329
CLSPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45041
Distal myopathy with anterior tibial onset	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.212
GSE110268_1_v_3_foxd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE215314_0_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4271
GSE65617_5_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8323949-pcbi.1009228.s007.xlsx-HNSCC_ALL_exceptLN-X17_ZNF717	Rummagene Transcription Factor Associations 2026	1.0	null
GSE174701_5_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE189653,GSE203344_4_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE185519_4_v_7_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RNASET2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75654
PMC12396377-jcb_202307079_tables1.xlsx-Fig_1C_i_-_iii_right-y_TFEB_KO_LLOMe_VS_WTLLOMe_UP_TFEB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE248045,GSE248046_6_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE240645_3_v_2_u90926_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Progeria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.732
Malignant hyperthermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.141
PMC2694838-1471-2164-10-241-S3.xls-Sheet1-Commonly_altered_genes_by_ZNF191_overexpression_and_knockdown_ZNF24	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-7_DEGs_USF2-KO_vs_control-Gene_Symbol_USF2	Rummagene Transcription Factor Associations 2026	1.0	null
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
NAAA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01744
PMC11282827-40659_2024_524_MOESM5_ESM.xlsx-SOX14-sequence_name_SOX14	Rummagene Transcription Factor Associations 2026	1.0	null
GSE238116_1_v_0_egr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5351
SFMBT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22676
PDCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41186
MTMR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90064
Twist2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.8157
GSE130396_8_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
VAMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07787
Autosomal recessive limb-girdle muscular dystrophy type 2O	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.261
C17orf75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33434
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.8607
Fibrosarcoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.322
GSE193999,GSE194000_3_v_2_atf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TBCCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17253
LPAR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00082
GSE133516_5_v_6_kat7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Meiotic nuclear membrane microtubule tethering complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.682
GSE139239_2_v_5_ddr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Osteopoikilosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.563
HEATR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21724
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.18
GSE238018_1_v_0_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
CDS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10634
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.18
GSE123943_1_v_3_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210580_4_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAU2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44708
Congenital muscular dystrophy due to LMNA mutation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.214
GSE133213_10_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE203181_0_v_1_phosphoramidon_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE169152_3_v_2_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Organelle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Asynchronous muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.501
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.7291
GSE96777,GSE96778_1_v_0_zbtb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE174701_1_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216273,GSE216292_14_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Megakaryoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.671
GSE248045,GSE248046_0_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMPCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7951
GSE186065_0_v_1_sirt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE133213_6_v_5_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ADISSP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23521
GSE171572_5_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE197564,GSE198512_0_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61235
PITPNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68668
PMC12774775-mmc2.xlsx-PAR_RARG_merge_q5_Narrow_subKO-Gene_Symbol_RARG	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney - Cortex	GTEx Tissue Gene Expression Profiles 2023	1.0	3.27107
496100332_HIP_possible Alzheimer's disease_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.13594
GSE148252_7_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nuclear membrane protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.743
GSE226355,GSE226357_1_v_0_ybx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100499_PCx_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.24438
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-DEG_MDDC_C91-PL_LPS_vs_MDDC_Jurkat_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.1284
Indeterminate leprosy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.14
Myoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.901
PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Significant_DE_genes_in_AKT1_vs_KLF4_meningiomas_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Unnamed_4_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_x_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE167324_1_v_0_eif4e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Tcf21	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	43.9079
GSE139987_1_v_2_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
lipid phosphatase activity	GO Molecular Function Annotations 2025	1.0	null
GSE153836_11_v_9_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE162739_8_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WDR33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06271
GSE125014_6_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Chromocenter	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.571
Sarcoglycan complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.502
GSE228181_2_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TFAP2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	157.101
Congenital myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.182
TFAP2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	147.168
GSE77795_2_v_1_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE163052,GSE163198_2_v_7_hira_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE160083,GSE160084_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE197257_0_v_1_gpd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4791
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.9994
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Autosomal recessive limb-girdle muscular dystrophy type 2N	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.188
Plantaris muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.287
ZBTB11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2697
GSE217405_0_v_1_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7378
GSE121809_1_v_0_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_11_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.702
GSE89018_6_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142210_3_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE217405_3_v_2_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_12_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6696
Nuclear pore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.484
ASTE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35008
VPS25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90708
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_LF_species_not_found_in_common_genes_of_R_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6078963-41467_2018_5311_MOESM5_ESM.xlsx-48h_KD_UP_Vs_ATAC-mgi_database_human_gene_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NAA20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46851
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.14684
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7613
GPKOW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03336
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.2843
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
SUGP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90691
TRAF3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79478
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7043
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-Row_names_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1069
NSA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25395
TIMMDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26774
PLEKHA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36847
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
WA-01 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.555
GSE223008_7_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE152055_2_v_3_mpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE166169_1_v_3_elp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE175787_5_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
Electrocardiogram morphology (amplitude at temporal datapoints)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.822185
GSE153836_14_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE74251_0_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Carcinoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.817
GSE185944_0_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE217405_3_v_2_osimertinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
sphingosine-1-phosphate phosphatase activity	GO Molecular Function Annotations 2025	1.0	null
GSE112962,GSE112963_2_v_1_ddx5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Fibrosarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.25
GSE123943_4_v_3_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
DYNC2I1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01981
GSE236072,GSE236075_2_v_1_ccr6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE220914_1_v_0_zdhhc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE153836_11_v_2_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Nuclear lamina	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.931
GSE89154_1_v_2_proscillaridin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nuclear envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.947
HRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93944
ZNRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50761
GSE237040_2_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE145915_5_v_1_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SPTSSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00329
PMC9019027-42003_2022_3332_MOESM3_ESM.xls-Table_S1_HUVEC_MED23-KD_DEGs-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
RPS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01296
PMC7941712-40478_2021_1135_MOESM12_ESM.xlsx-Table_S4D_DEG_ST-EPN-RELA-Unnamed_6_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM168	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74373
GSE81803,GSE81912_0_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8323949-pcbi.1009228.s007.xlsx-X17-Unnamed_0_ZNF717	Rummagene Transcription Factor Associations 2026	1.0	null
Intrinsic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.143
PMC11551974-gpsych-37-6-s001.pdf-14-FOXF1_FOXF1	Rummagene Transcription Factor Associations 2026	1.0	null
Transmembrane actin-associated (TAN) line	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.744
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4181
GSE224969,GSE224971_0_v_5_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BTAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67873
496100646_TCx_probable Alzheimer's disease_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09613
HROB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46146
GSE149442_1_v_0_gdpd3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE242367_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Autosomal recessive limb-girdle muscular dystrophy type 2W	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.369
Myosin XII complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.178
GSE87617_1_v_0_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MGAT5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10458
GSE175787_4_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
EIF1AX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06233
GSE195663_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
RRP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39063
ALDOA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51205
PMC12619835-41467_2025_66007_MOESM12_ESM.xlsx-KLF5_activated_H3K27ac_T3M4-Nearest_Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6714
MED27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70863
GSE224096_2_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21891
ZNF790	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54608
PMC8423434-mmc7.xlsx-KLF4_HENSM-Genes_n_2172_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
Organism form	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5802
PMC6545035-12943_2019_1031_MOESM7_ESM.xlsx-Sheet1-Supplementary_table_5_The_significant_reduced_genes_in_TET1_knockdown_cells_TET1	Rummagene Transcription Factor Associations 2026	1.0	null
CIP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30734
GSE195559_8_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142210_3_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8639975-41598_2021_98792_MOESM3_ESM.xlsx-S5_-_MEF2A_core_enriched-Unnamed_2_MEF2A	Rummagene Transcription Factor Associations 2026	1.0	null
GABARAPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93431
IMMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52515
NAT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36425
GSE211177,GSE211178_4_v_1_ets1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TEX261	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23316
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.7837
YPEL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18086
Satellite cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.252
SRSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23801
GSE77178_2_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE175787_13_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Euchromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.375
TINF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07461
Myoblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.745
GSE238018_1_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
Melorheostosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.309
Nuclear membrane microtubule tethering complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.682
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.75586
Nuclear pore outer ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.964
GSE223008_9_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Psoas major	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.547
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6659
Atf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.6546
TPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81243
Flexor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.263
Muscle stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.148
FANCI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67412
PMC9084694-RMB2-21-e12464-s005.xlsx-GV_MI_MII_GV-up-GeneName_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
IL17RD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03343
HPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53791
GSE195663_0_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1594
SRRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78111
PMC8803621-mmc6.xlsx-Sup_Fig5A_genes_list-Genes_with_following_MEF2_motifs_around_their_TSS_CTAWWWATA_RSRFC4_Q2_MEF2_Q6_01_MEF2_03_MEF2_02_RSRFC4_Q2_from_GSEA_MEF2A	Rummagene Transcription Factor Associations 2026	1.0	null
fibro-adipogenic progenitor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.272
GSE186287_1_v_3_ufm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8423434-mmc7.xlsx-SOX2_HENSM-Genes_n_2733_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7673140-41467_2020_19575_MOESM4_ESM.xlsx-Data_S1d-List_of_2302_of_genes_differentially_regulated_by_SOX2_FDR_0_1_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC3610249-1471-2164-14-184-S4.xls-miR-331-3p_targets-NR2E3_NR2E3	Rummagene Transcription Factor Associations 2026	1.0	null
Testicular cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE224096_1_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE186005_1_v_2_klf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF692	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.6825
ANKLE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06225
Limb bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.924
GSE87412,GSE92423_3_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53144
Restrictive dermopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.37
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6192
GSE185519_3_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Extensor digitorum longus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.32
ACAD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08147
GSE125153_1_v_0_bcl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210580_4_v_12_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.342
SKA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47899
CORO2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8224
Pelger-Huet anomaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.396
TMEM120B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75359
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.9914
GSE226249_2_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SCN4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22616
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.9058
CARD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16414
ZNF714	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48088
BNIPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00506
Primary hyperoxaluria type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.366
GSE210682_2_v_1_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Organelle envelope	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GSE175787_8_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Autosomal recessive limb-girdle muscular dystrophy type 2P	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.424
MED31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07563
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KRT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30553
GSE184892_6_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZBTB46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5533
F2RL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75009
Organelle subcompartment	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
PMC10928104-41419_2024_6576_MOESM4_ESM.xlsx-S14-MYBL2_targets_MYBL2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE68155_1_v_0_gpr3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE144745_0_v_1_mettl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
RPL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16886
GSE88819_11_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158743_1_v_2_nfkbia_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PPP1R12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.69088
Nuclear envelope lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.135
Ascl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.4274
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.1259
PMC10805842-41531_2024_638_MOESM1_ESM.pdf-7-ARNT_ARNT	Rummagene Transcription Factor Associations 2026	1.0	null
GSE199660_1_v_0_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE157282_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RTEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33485
GSE146612_1_v_3_amiodarone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Duchenne muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.141
TXNL4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33368
Muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.122
PMC11214527-mmc5.xlsx-TP53-gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
QGY-7703 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.011
Myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.95
SNRPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11476
chr9_131306805_T_C_b38	GTEx eQTL 2025	1.0	1.57818
Buschke-Ollendorff syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.092
X-linked Emery-Dreifuss muscular dystrophy 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.401
Colon - Sigmoid	GTEx Tissue Gene Expression Profiles 2023	1.0	5.07657
Endoplasmic reticulum tubular network	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.414
CAMK2N1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27478
TMEM245	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85766
ZBTB43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74757
GSE120370_4_v_1_thrombin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.945
GSE120595_0_v_4_arid2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12571111-qiaf131_supplementary_data.xlsx-ST2-Supplementary_Table_2_Results_of_the_two-sample_MR_analysis_on_the_causal_role_of_CD4_T_cell_expression_profiles_on_CRC_development_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
HEYL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0443
GSE206729_4_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE224004,GSE224005_0_v_8_chd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11909984-12943_2025_2285_MOESM1_ESM.pdf-6-MEIS1_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.612
Nuclear membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.708
GSE199921_1_v_0_romidepsin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216273,GSE216292_14_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE185519_6_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZBTB8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00669
PMC11058205-42003_2024_6202_MOESM5_ESM.xlsx-Data2c_CEBPA_ChIP-Unnamed_9_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1099
KBM-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.786
GSE152937_12_v_1_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Gizzard smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.773
Endoplasmic reticulum subcompartment	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE137954_4_v_2_smyd3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE175787_5_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6606599-41598_2019_45777_MOESM14_ESM.xlsx-SAVA_DE_genes_promoter_DMRs-Unnamed_29_TBXT	Rummagene Transcription Factor Associations 2026	1.0	null
GSE184892_7_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SLC7A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10514
GSE228181_0_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Autosomal recessive limb-girdle muscular dystrophy type 2S	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.208
PMC10769314-NIHMS1954782-supplement-9.xlsx-Table_S7B-Table_S7B_Frontal_cortex_relative_gene_expression_from_post-KD_and_pre-KD_recipient_mice_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE98964_1_v_4_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE235701,GSE261434_2_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
LHX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45208
Bietti crystalline corneoretinal dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.573
ANAPC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78401
GSE182179_2_v_1_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE93674_1_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44917
Endoplasmic reticulum	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE151612_0_v_7_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE202434,GSE202438_15_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Autosomal dominant Emery-Dreifuss muscular dystrophy 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.256
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_y_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE211126_1_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE174701_1_v_7_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100628_FWM_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.18808
THAP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.6244
Soleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.099
EXTL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39799
SNF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11296
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_2_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210101,GSE210114_0_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE129370_2_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8051
Retinal rod	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.74
GSE176008_0_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
X-linked recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.041
MRPL32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07661
ROCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28775
PMC10120965-pwac038_suppl_supplementary_table_s4.xlsx-siFOXP1-2_vs_siNC-Differentially_Expressed_Genes_DEGs_in_hCMs_upon_Silence_of_FOXP1_FOXP1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210101,GSE210114_1_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Nuclear periphery	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.215
GSE206729_2_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE101527_0_v_1_smad4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE203072_2_v_3_rpl3l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nuclear outer membrane-endoplasmic reticulum membrane network	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
NHP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5683
RBM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36586
Twitch muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.075
GSE198982,GSE198986_1_v_2_daunorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MED26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19626
PRDM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21529
GSE142210_3_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE89018_10_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTF3C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27904
GSE148066,GSE157787_3_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE128634,GSE128636_4_v_5_foxo1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FMNL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43719
GSE62843,GSE64371_4_v_0_furan_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Muscular atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.151
NSL complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.644
PMC12774775-mmc2.xlsx-PAR_RARG_merge_q5_Narrow_subKO-ENSEMBL_ID_RARG	Rummagene Transcription Factor Associations 2026	1.0	null
GSE86021_0_v_1_crenolanib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE185519_3_v_7_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE128634,GSE128636_4_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Nuclear envelope	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GSE129244_3_v_1_lmo2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0318
Lamin filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.673
GSE133516_0_v_3_kat7_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149880_2_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HERC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51008
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE92434_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Foot	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.156
Pericentriolar material	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.924
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1637
Dystrobrevin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.729
GSE138633_2_v_0_bag3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Primary hyperoxaluria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.357
PR interval	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.1301
PMC7617265-EMS137094-supplement-Supplementary_Tables.xlsx-ST18-gene_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
GSE102467_1_v_0_pazopanib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	83.8507
GSE130401_4_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5116
GSE200388_0_v_1_gemin5_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10123531-NIHMS1874945-supplement-Table_S3.xlsx-DAY1_SOX17_peaks-Gene_Name_SOX17	Rummagene Transcription Factor Associations 2026	1.0	null
TRAM1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08026
Neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.183
GSE123002_0_v_1_srsf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142684_4_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Progeroid syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.684
Specific developmental disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.18
GSE142210_9_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158502,GSE158506_3_v_0_fat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE77108_0_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE213588_10_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
AAAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12957
SBK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38693
PMC8016886-41419_2021_3630_MOESM6_ESM.xlsx-Sheet1-Table_S5_Differentially_expressed_genes_identified_between_HOXC6-low_and_HOXC6-high_expression_CRCs_using_TCGA_cohort_HOXC6	Rummagene Transcription Factor Associations 2026	1.0	null
496100431_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.7261
496100338_HIP_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.07426
GSE175787_5_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE168596_1_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
LRSAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93446
Autosomal recessive limb-girdle muscular dystrophy type 2M	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.144
TRAPPC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43829
NDUFAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27963
496100631_PCx_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.52244
SNRPD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69454
GSE208096_1_v_0_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FBXO41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85808
TMBIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36848
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.3139
PMC11385078-jciinsight-9-172336-s272.xlsx-1DEseq2_Report_AA_BL_vs_EA_BL-Unnamed_1_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Gastrocnemius	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.247
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8711
CARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44873
GSE102132_2_v_1_irf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC3636213-pgen.1003459.s012.xlsx-Sheet1-KD_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE174498,GSE174500_0_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF236	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22505
GSE199606_1_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE184210_0_v_3_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCAN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39459
SASS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.5384
SEPTIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53119
GSE213588_8_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DMAC2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27038
GGT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45192
PMC11462941-CAS-115-2947-s001.pdf-240-ZFX_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE211989_3_v_2_nlrc3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PRELID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89547
GSE184892_4_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LSM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31298
TIPRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92887
GSE240258_0_v_1_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Wolfram syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
Omasum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.673
TNFRSF12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19199
GSE120595_5_v_4_arid2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PPP6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91081
TTK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58584
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4274
GSE171712_0_v_1_scgb1a1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.8606
Emery-Dreifuss muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.746
GSE151412_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE133070_3_v_1_prss1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE130383_2_v_0_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Smooth endoplasmic reticulum membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.657
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2537
TRAPPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42262
Embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZNF682	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.4622
GSE143662_0_v_1_dcp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199255,GSE199356_6_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10591418-12711_2023_849_MOESM11_ESM.xls-AA_3W_vs_LS_3W-gene_name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE131649_2_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
C2CD2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26347
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	43.1107
EPN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4822
GSE77108_0_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.7762
NFIC::TLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0625
GSE173873_1_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6599263-13073_2019_654_MOESM2_ESM.xlsx-CAR1_tsv-gene_name_NR1I3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE131649_4_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MYNN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14695
PMC3226433-1756-8935-4-20-S1.XLS-Table_S4_Myc_KD_gene_exp_change-Genes_up-regulated_in_Myc_KD_hESC_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE162739_4_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11906354-41588_2025_2087_MOESM4_ESM.xlsx-ST12-Unnamed_3_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
ESYT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37968
PHC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01016
Autosomal dominant Emery-Dreifuss muscular dystrophy 7	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.563
GSE96649_1_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
NFIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0106
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5805
GSE199606_3_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE169697,GSE169725_0_v_5_prrx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.228
RHOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97539
Autosomal recessive limb-girdle muscular dystrophy type 2U	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.405
Tibialis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.375
GSE175787_5_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213442_1_v_0_kpna2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE171572_0_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9859043-elife-78421-supp9.xlsx-LHX8_P-Gene_symbol_LHX8	Rummagene Transcription Factor Associations 2026	1.0	null
GSE185519_1_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SQLE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02354
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-KLF15_KLF15	Rummagene Transcription Factor Associations 2026	1.0	null
Placenta	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE89018_1_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EIF3H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00877
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
TM7SF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43304
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9853
PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5	Rummagene Transcription Factor Associations 2026	1.0	null
Ebf2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.466
PSMB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19405
GSE112762,GSE112767_2_v_0_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100355_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.17661
PMC8481886-Table_1.xlsx-A_subsets-UC_MSC_bone_marrow_MSC_adipose_tissue_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
laminin-2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.576
SLMAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03658
496100589_PCx_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.08149
PMC6718408-41467_2019_11884_MOESM6_ESM.xlsx-TAD_genes_ST-EPN-RELA-Unnamed_4_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
TRMT10C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57922
Nuclear pore linkers	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.551
NR1I2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38557
GSE118939_1_v_0_nras_human	RummaGEO Gene Perturbation Signatures	1.0	null
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2467
HARBI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29777
PMC11749115-loae020_suppl_Supplementary_Table_S2.xlsx-CHOP-high-gene_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
NOB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9819
MDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29444
GSE200673,GSE200691_2_v_4_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TFAP2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	170.285
GSE175787_5_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TFG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44266
CDK11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72158
GSE178907_5_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Autosomal recessive limb-girdle muscular dystrophy type 2T	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.344
TGDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04026
GSE197564,GSE198513_2_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EMC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77394
HT-1080 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.353
GSE101336_1_v_0_decitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE231720,GSE231724_2_v_1_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE147613_1_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.6721
GALNT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85786
MCRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03229
GSE88819_5_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE213219_0_v_1_st3gal3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PRPSAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29884
Microtubule organizing center attachment site	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.636
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.299
GSE182179_2_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KCNJ11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04126
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-RXRG_RXRG	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6606599-41598_2019_45777_MOESM14_ESM.xlsx-SAVA_DE_genes_promoter_DMRs-Unnamed_22_TBXT	Rummagene Transcription Factor Associations 2026	1.0	null
PMC2694838-1471-2164-10-241-S2.xls-Sheet1-Regulated_genes_by_ZNF191_knockdown_ZNF24	Rummagene Transcription Factor Associations 2026	1.0	null
Mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.851
FLAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58894
RNF141	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22035
C12orf43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07774
EHF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7849
GSE123861_1_v_0_sin3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Congenital muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.808
Neuroendocrine tumor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.858
Myotube	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.951
GSE104022_3_v_4_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
bad5	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.546
TJAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20698
GSE216273,GSE216292_0_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Great saphenous vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.569
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.245
Pparg::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	56.5447
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1437
GSE198826,GSE198911_1_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
chr9_131301610_T_C_b38	GTEx eQTL 2025	1.0	1.85035
GSE129241_4_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7304190-13229_2020_355_MOESM18_ESM.xlsx-Supplemental_Table_5-iPSC_NPCs_TCF4_TCF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE68925_1_v_0_fasudil_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ATP5PB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82158
Greenberg dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.81
GSE108084_3_v_2_epinephrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE211126_3_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE207433_2_v_3_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE131649_4_v_5_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2035
PMC8709578-elife-69843-supp4.xlsx-HSF1_ChIP-seq_peaks-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.344
Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.9785
PMC4387713-supp_gad.255984.114_Table_S3.xlsx-S3B-Up_Dpy30_KD-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SUGP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0632
Cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.291
GSE175787_11_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
WDFY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.65677
Dilated cardiomyopathy 1H	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.154
GSE202284,GSE202289_3_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6299095-41389_2018_108_MOESM4_ESM.xlsx-T47D-TRPS1_peak-gene_symbol_TRPS1	Rummagene Transcription Factor Associations 2026	1.0	null
Lhx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.7335
GSE139016_3_v_2_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE181959_3_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Teratocarcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE157960_2_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216043_11_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cortical endoplasmic reticulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.428
Autosomal dominant limb-girdle muscular dystrophy type 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.181
DGKD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0668
JARID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01833
MAP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9373
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.47012
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_3_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
ENSG00000284691	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30719
ZNF708	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0318
Dilated cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.218
MIEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25046
GSE199660_1_v_3_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CDCA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38089
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.353
Nemaline myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
DHX36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30893
LMBR1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93943
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
TRIP13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60481
Slow twitch muscle fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.728