association	dataset	threshold value	standardized value
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5959
DDX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5935
BRD-K90230495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05574
BRD-K78612514	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18599
4959_MED9_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.512639
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	66.8781
PSAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70945
phosphate-containing compound metabolic process	GO Biological Process Annotations 2025	1.0	null
Quadriceps	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.124
GSE140200_1_v_3_trim59_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN013_HEPG2_24H:K12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02845
GSE119498_0_v_10_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ELF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9193
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	109.395
BRD-K80298486	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77158
GSE228181_4_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142210_2_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Thyroid	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.74223
GSE158182_3_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.083
Blood plasma	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE150215_1_v_0_etl4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K45620289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08654
GSE169356_2_v_4_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K33044659	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23928
HAND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11461
Synovial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.579
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.3873
POLR2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74357
GSE125014_6_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE202434,GSE202438_2_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K16598630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37554
BRD-K10105458	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.32975
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6001
GSE149903_3_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8772
Femur	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.924
CRCGN017_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.43352
BRD-K72335238	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73806
5983_OSBP_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.16248
PMC11615365-41467_2024_54246_MOESM6_ESM.xlsx-KK47-Numb-KD_vs_Ctr-KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE123502,GSE123504_1_v_0_chd4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ASPHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16068
BRD-K36134372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96595
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-DEG_MDDC_C91-PL_LPS_vs_MDDC_Jurkat_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE87615_1_v_3_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SPDEF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0465
RNF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20291
Adult stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.232
EIF5AL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41299
GSE235701,GSE261434_2_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
7505_RPS16_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.00186
GSE202434,GSE202438_12_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Osteocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.627
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.4618
GSE152441,GSE152442_7_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K45874102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35366
4805_MAP2K7_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.07903
CRCGN017_MCF10A.TP53.M_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.70647
MFAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14724
BRD-K91624805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05436
Periodontal ligament cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.622
5927_OGDH_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.611059
BRD-K96733881	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81624
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92201
VCY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52806
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K32947579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15301
RFX7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4609
CRCGN017_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.68198
2105_DDX18_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.38895
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1372
BRD-K69132276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58364
CRCGN009_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.45647
PMC12254391-41598_2025_8960_MOESM5_ESM.xlsx-Suppl_Table_6_DEG-Supplemental_Table_6_Differentially_Expressed_Genes_DEG_between_siRNA_DLX4_and_siRNA_control_n_3_RA_FLS_cell_lines_per_treatment_group_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K97013733	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15325
GSE226770_1_v_0_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KLF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	79.0953
BRD-K72298899	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19308
GSE209598_1_v_2_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K84788922	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88998
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE200352_5_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PDCD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72488
GSE221327_10_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7029036-41598_2020_59469_MOESM2_ESM.xlsx-NR4A1_vs_GFP_adj_pval_0_05-Gene_NR4A1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE153189_1_v_0_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Blood platelet	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE152441,GSE152442_7_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Complex of collagen trimers	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.298
Thoracic spine	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.711
RPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28041
BRD-K54507743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0598
Rheumatoid arthritis disease specific synovial fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.58
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4417
BRD-K11437379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18308
Joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.21
GSE158834_11_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE164874_5_v_14_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K79562803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89485
Whole Blood	GTEx Tissue Gene Expression Profiles 2023	1.0	2.11069
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.7527
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.799
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-10_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE234514,GSE234516_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K71893034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0482
Chondrocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.147
Inner chondrogenic layer of perichondrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.147
GSE238005_0_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K90133009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03825
collagen-containing extracellular matrix	GO Cellular Component Annotations 2025	1.0	null
GSE153836_14_v_5_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K64055724	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60107
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.932
BRD-K97487406	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47097
CRCGN017_MCF10A.TP53.M_24H:G12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.74163
HPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08763
GSE142210_9_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
TRAIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46739
GSE96641_5_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
8227_SNRPC_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.768881
GSE221577_1_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE74251_2_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Viral RNA-directed RNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.963
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.625
BRD-K57907671	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36645
BRD-K63970901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8962
Tendon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.086
BRD-K52881132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76281
Interdigit	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.572
CRCGN011_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.95065
PMC10290283-biol-2022-0622-sm3.pdf-223-ZNF576_ZNF576	Rummagene Transcription Factor Associations 2026	1.0	null
Brain - Putamen (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.01718
2790_EXOSC3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.519179
GSE125219,GSE125221_4_v_2_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
HMBOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0314
GSE140607_1_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE118816_2_v_3_myo1c_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K24997610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40478
GSE120756_2_v_9_tet2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Plasma membrane light-harvesting complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.777
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9285
HAUS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89622
GSE206870,GSE206872_0_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Epiphyseal growth plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.019
Thrombospondin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.339
POM121C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54071
BRD-K66013406	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.09155
CRCGN011_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.53528
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.753
GSE185519_3_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9837
Pharyngeal arch cartilage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.289
Lhx8	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	13.7675
PMC8390679-41467_2021_25186_MOESM5_ESM.xlsx-PBX3-Unnamed_1_PBX3	Rummagene Transcription Factor Associations 2026	1.0	null
SMUG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54106
Elastic fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.754
Tarsal bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.966
Style	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.478
GSE200352_10_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.4889
PMC6754502-41598_2019_50051_MOESM3_ESM.xlsx-Fay_Heat_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
phosphatidate phosphatase activity	GO Molecular Function Annotations 2025	1.0	null
BRD-K81372179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.54766
GSE190186,GSE190188_8_v_5_apoe_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K34910830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12613
BRD-K47662318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57221
BRD-K63468420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60878
Chondrocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.371
BRD-K32930844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37128
BRD-K31479652	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01712
GSE152432_5_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAZ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	136.087
GSE48812_4_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
Dendritic branch	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.786
GSE129725_1_v_5_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Np	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.207
Citrullinemia	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.571
BRD-K18864235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41155
CRCGN017_MCF10A.TP53.M_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.03319
GSE164874_5_v_12_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE148066,GSE157787_11_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Osteoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.064
CRCGN010_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.85715
CRCGN015_MCF10A.WT.HP_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.92618
GSE238018_3_v_2_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199606_5_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.6067
EXOSC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17573
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.9307
TAF1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3456
BRD-K93503664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08425
GSE184892_7_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
8656_TAF1A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.667214
GSE175787_8_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4595011-pgen.1005555.s001.xlsx-MITF_UP-regulated-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.161
Vascular endothelial glycocalyx	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.595
BRD-K96778609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69458
Corneal epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.416
CRCGN013_HEPG2_24H:N13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.55822
GSE219195_1_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE226770_1_v_6_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Chondroclast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.072
GSE142588_2_v_1_cinobufagin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE119498_6_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE182680,GSE182683_0_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CDK10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27967
GSE126345_9_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Parotid gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.835
GSE205729,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.786
GSE210388_2_v_0_ror2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_24H:M23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0436
KCTD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11892
BRD-K12824862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07325
GSE207863_0_v_1_hdac5_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN013_HEPG2_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.03984
GSE197850_4_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K93900188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.23642
Osteogenic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.14
GSE135030_8_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8481886-Table_2.xlsx-A_subsets-common_MSC_AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE175787_11_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE261563_9_v_4_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
Incisor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.836
CRCGN010_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.15635
Fibrinogen complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.545
GSE135030_8_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lhx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.3767
Femorotibial joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.358
GSE236502_2_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
ERF::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0725
6845_PSMA5_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.516884
MCF7_Navitoclax_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0153609
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.6809
BRD-K03214579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0471
Egg white	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.606
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.9348
ZNF740	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	135.144
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.8816
GSE122990,GSE123061_0_v_1_urod_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Plantaris muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.796
GSE221327_8_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_7_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Interfascicular region	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.833
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.3402
GSE128730_4_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE142210_11_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE94849_6_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC3435504-msb201237-s2.xls-Supp_Table_4c-WT1_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
Forelimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.592
5869_NUDT21_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.742877
Arx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.5144
TEAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4151
GSE214823,GSE214824_0_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE217776,GSE217829_2_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K13472433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.29523
GSE132369,GSE132371_2_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE74383_2_v_0_ror2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE123689_1_v_0_cbx8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.027
GSE213228_2_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KLF11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.1758
BRD-K50045741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96552
BRD-K07895476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.58019
9804_WDR12_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.504639
BRD-K41307047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41446
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.1586
BRD-K95729740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54256
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.4905
RAB14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51123
BRD-K00502656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59648
GSE144231_4_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE233679_6_v_8_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.2947
GSE203308_14_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE85880,GSE85881_0_v_2_tretinoin_human	RummaGEO Drug Perturbation Signatures	1.0	null
3372_GINS4_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.530811
CNOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38262
RBM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13269
BRD-A03668899	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82265
SOX13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3177
BRD-K66619295	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45893
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.9691
BRD-K34264024	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90795
BRD-K51535480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21113
CRCGN009_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.15517
BRD-A67508925	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09567
GSE233679_14_v_4_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE211262,GSE211263_3_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ERG_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
GSE155162,GSE155169_1_v_2_buparlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.05965
BRD-K03191078	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89582
GSE119564_2_v_0_zfp217_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Artery wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.769
BRD-K16911140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45095
GSE203429_0_v_1_angptl8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K77554584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5807
GSE173201_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K19020285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99578
GSE233679_14_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
EC-62-OE64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.268034
Calcaneal bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.428
6747_PRIM1_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.03138
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.1033
5733_NOL11_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.715856
GSE159473_0_v_1_eif5a2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K02681754	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04951
GSE153836_11_v_2_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE124410_3_v_0_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Tooth	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.565
BRD-K74803017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9962
GSE221386_3_v_0_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_12hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5291205-srep41905-s3.xlsx-LPS_datasets_gmx-Unnamed_6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K16940345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7691
BRD-K90356496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95785
PMC8972054-MSB-18-e10682-s011.xlsx-Dataset_EV4-THAP3_THAP3	Rummagene Transcription Factor Associations 2026	1.0	null
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0929
GSE154577_2_v_12_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE77108_3_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
7477_RPL7A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.618607
Spleen	GTEx Tissue Gene Expression Profiles 2023	1.0	2.22986
GSE138050,GSE148257_1_v_2_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K65663356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54457
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1483
BRD-K28165728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88312
GSE201309_5_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE77108_8_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE238116_3_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.998
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6227
PMC12254391-41598_2025_8960_MOESM5_ESM.xlsx-fig-Supplemental_Table_6_Differentially_Expressed_Genes_DEG_between_siRNA_DLX4_and_siRNA_control_n_3_RA_FLS_cell_lines_per_treatment_group_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE152699,GSE152723_0_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.7266
SERF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37184
BRD-K11835238	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56767
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5914
PMC11604901-13555_2024_1298_MOESM1_ESM.pdf-76-RELB_RELB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE161295_4_v_3_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE147662_2_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158182_5_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE153871_1_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.41857
Lysosphingolipid and LPA receptors	Reactome Pathways 2024	1.0	null
1441_CDK7_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.09464
10703_ZNRD1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.51773
BRD-K96491664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.45933
BRD-K25203350	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01526
External encapsulating structure	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Plasma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE228181_0_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE153189_2_v_0_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NEUROG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4476
GSE213588_10_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE232218_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.6819
BRD-K35288418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57435
PMC8065135-41467_2021_22068_MOESM6_ESM.xlsx-E_MYOG_binding_in_downreg-Unnamed_1_MYOG	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K96745500	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10549
GSE236003_2_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K42732309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50496
Pericardial mesothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.311
emetine-hcl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25662
Cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2982
KLF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.6843
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.834
Zbtb2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.684
GSE193993_5_v_3_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Bone marrow cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Dlx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.8015
Extensor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.377
SP8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.4639
OTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49516
GSE111660_4_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182680,GSE182683_0_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE165122_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
9443_TWISTNB_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.859189
BRD-K14533399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58244
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0724
CRCGN015_MCF10A.WT.HP_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.33687
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.0741
Parallel fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.729
BRD-K44304623	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2975
BRD-K06408981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98611
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.701
Adhesive extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.966
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.7105
CRCGN016_MCF10A.WT.HP_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5667
PMC12619835-41467_2025_66007_MOESM13_ESM.xlsx-Sheet1-T3M4_KLF5_activated_H3K27ac_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K41762421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02764
BRD-K77733130	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34356
GSE185519_3_v_5_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE223334_3_v_0_bcl11b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GID4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11682
BRD-K56775726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.09496
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3227
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8553
GSE152699,GSE152723_3_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K87853964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43654
GSE123734_1_v_0_mien1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Hypobranchial	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.51
GSE148066,GSE157787_8_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169205_0_v_5_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE101336_1_v_0_decitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K14203360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9331
Lhx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.5529
GSE216540_1_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
Vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.701
SRPRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22046
GSE158834_11_v_5_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K88671309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26003
Stigma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.494
BRD-K79523827	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52379
BRD-K60807536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34013
GSE131660_2_v_0_piperlongumine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE188458_2_v_4_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Synovium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.037
GSE226091,GSE226092_0_v_1_sall1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2658
C1orf109	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10501
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0674
Knee	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.991
BRD-K95569142	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07733
LKAAEAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13164
BRD-K60578515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0703
4953_MED30_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.540567
BRD-K41814083	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05774
7527_RPS5_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.528411
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.9276
EIF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19318
BRD-K39985369	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39082
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2529
PMC12852376-SupplementaryFile1.xlsx-Supplementary_Table_S4-Analysis_of_the_association_between_QTL_and_iridocyclitis_using_MR_and_SMR_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.461
BRD-K20199304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39305
BRD-K94742710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46963
Sternal cartilage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.788
RWDD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05328
GSE164874_5_v_3_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.3766
GSE205976,GSE205978_1_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	85.0457
BRD-K88679751	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24943
BRD-K96284156	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.50145
GSE172019_2_v_3_rnf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K22679163	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.4934
GSE202744_1_v_0_toyocamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.4
3677_HEATR1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.712028
CRCGN015_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.42445
CDK12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60087
RASSF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04097
Multimerin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.873
GSE202434,GSE202438_12_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE190555,GSE190557_2_v_0_chd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE242083,GSE242098_2_v_5_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE161864,GSE161866_0_v_2_ror2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE220813_0_v_1_zfp750_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-BrtoFay_Thermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Myosin phosphatase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.681
UBR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13396
BRD-K88447092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65061
PMC4595011-pgen.1005555.s003.xlsx-MITF_UP-regulated-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K65265098	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38173
pg4	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.704
DDX54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01816
betamethasone-valerate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35839
GSE130715_1_v_0_budesonide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Differentially_expressed_genes_identified_in_bulk_RNA-seq_of_FOXO1-_-_vs_FOXO1_hMSCs_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE147056_0_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE239844_4_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Tooth enamel	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.965
BRD-K56761719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79466
BRD-K71607378	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56542
Insect labium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.22
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5944
Tibia	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.327
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.9638
Chondrosarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.915
ZNF707	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.8185
GSE215351,GSE215794_1_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6944
LBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7409
BRD-K90505752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49888
PMC11003700-pbio.3002240.s013.xlsx-siMYCN_RNA_IMR32_48h_q_0_05_1_5-Table_S6_Genes_commonly_and_differentially_regulated_by_MYCN_and_WDR5_in_IMR32_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
GSE175787_5_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC3728595-srep02327-s1.pdf-1622-RORA_RORA	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K42804674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89508
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5625
PMC4909989-ncomms11840-s2.xlsx-down-regulate-TEAD4-FL_YAP_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K38724926	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.55115
GSE164874_5_v_1_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K79020643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19294
GSE157383_3_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K62964360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17525
GSE158834_11_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9912
CRCGN012_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.19305
BRD-K57616143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34712
GSE131798,GSE131804_2_v_0_igf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157555,GSE157556_3_v_7_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CCT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16193
BRD-K43789905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59405
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.405
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-3_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
Sebaceous gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.19
Rhox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.4594
PMC9537523-41467_2022_33364_MOESM7_ESM.xlsx-scores_wilcoxon_1_MONTH_ORG-EN1_n_EN1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K52932858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65126
BRD-K44921612	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01237
Erg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.7063
BRD-K02362691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73559
GSE93674_1_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RBMX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.31661
Rough endoplasmic reticulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.302
GSE197850_4_v_2_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
laminin-4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.674
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.9695
TAF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44675
BRD-K75606012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86893
Neostriatum	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2578
GSE226584,GSE226589_2_v_0_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.25033
GSE201309_5_v_7_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_10_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Colo-38 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.818
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5444
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_3hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
IFT46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46359
BRD-K71604365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1895
GSE193282_3_v_1_cd44_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE128634,GSE128636_4_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE160817_3_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7532671-thnov10p10957s2.xlsx-Table_S6A-Table_S6A_Differentially_expressed_genes_DEGs_in_DDX5_KD_versus_WT_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
UFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35586
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	103.259
GSE128730_4_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE196104,GSE196106_2_v_0_vsx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Ankle joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.533
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9759
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.1098
GSE147959,GSE147960_5_v_3_stat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cartilage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.304
BRD-A01717111	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46171
CRCGN012_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.93323
BRD-K48459037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29395
GSE147664_0_v_1_arid1b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
2132_DDX56_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.559837
GSE131649_6_v_10_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.587
BRD-K77743611	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01709
BRD-K42139332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.006
GSE115542_2_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K12260863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14486
CRCGN016_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.45689
GSE148200_1_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.3195
1013_C18ORF32_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.644253
BRD-K79712504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18427
Bone marrow stromal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.341
BRD-K27374902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28126
post-anaphase microtubule array	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.345
GSE246184,GSE246195_0_v_1_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE217405_3_v_2_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
2731_ESF1_P1	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.603189
GSE232558_0_v_2_fbxl12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC3435504-msb201237-s2.xls-Supp_Table_4b-SP1_SP1	Rummagene Transcription Factor Associations 2026	1.0	null
4153_INTS8_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.765017
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5109
PMC11046918-12967_2024_5211_MOESM5_ESM.xlsx-C_FUS-DDIT3-eGFP_vs_eGFP-Table_S3_Regulated_genes_between_scaffold-cultured_HT1080_FUS_DDIT3-eGFP_cells_and_control_cell_lines_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K79438478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48371
GSE140441_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A50287893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75394
BRD-K89174739	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9634
BRD-K26376097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09778
Hereditary spastic paraplegia 35	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.543
KLF13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.9204
Tendon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Lumbar spine	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.927
GSE158182_3_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE182179_0_v_1_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE150055_0_v_1_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
Long bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.961
BRD-K01853144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30162
2125_DDX49_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.51829
DPP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45096
Tear gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.195
CRCGN015_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.16412
SPART	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44805
Pericardium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.61
GSE164874_5_v_13_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
2225_UTP25_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.65895
BRD-K99736408	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09509
GSE208096_1_v_0_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE89569_3_v_0_nr0b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE109565_12_v_4_glyphosate_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K21356734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64443
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.6087
GSE189859,GSE189861_0_v_2_idh1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HEBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31482
GSE102870_3_v_0_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.3432
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4915
GSE129241_3_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4595011-pgen.1005555.s003.xlsx-BPTF_UP-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K91696235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40706
PMC10534007-Table_2.xlsx-S5_unique_up_MSC_B-721_elements_included_exclusively_in_BFTC905_MSC_up_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K68705041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05299
6534_POLR1B_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.723777
GSE240386,GSE242143_1_v_5_morc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K19089958	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10201
Hip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.791
Hmx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.0743
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2157
Gynoecium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.48
GSE244233_1_v_0_quercetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Masseter	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.944
Synovia	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.732
MCF7_SNS-314 Mesylate_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0120858
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7848
BRD-K96449536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36963
Cancellous bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.845
6062_PAPOLA_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.98676
Sclerotome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.461
Membrane attack complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.084
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1353
GSE140937,GSE140938_0_v_2_slfn11_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K34311186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60537
GSE134375_4_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205729,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pterygium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.838
10738_ZWINT_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.529764
f2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.584
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.143
GSE181003_1_v_2_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
Dorsal fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.631
BRD-K77214780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.19873
Vocal fold	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.597
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.412
5089_NIFK_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.51131
GSE183327,GSE183328_1_v_0_ddit3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE120415,GSE120447_0_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE188458_2_v_0_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	1.0	null
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6599
3395_GLIS1_ENST00000312233.2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.551039
GSE151412_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6774
BRD-K21479004	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27727
GSE197555_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE207914_3_v_6_nudt7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68721
GSE189834,GSE189836_1_v_0_brd4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K33420995	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1655
CRCGN013_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.69552
GSE239844_6_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE125014_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K12741517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.21341
BRD-K96978561	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2974
GSE125219,GSE125221_4_v_8_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K35617935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99964
GSE131649_4_v_9_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
1972_CWC22_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.565079
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.701
Bone marrow	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE148066,GSE157787_5_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE127790_11_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE57871_8_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0859
7012_RAB1B_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.865529
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8184
PMC5287225-supp_gr.209163.116_Supplemental_Table_S4.xlsx-Table_S4-Supplemental_Table_S4_Differentially_expressed_genes_related_to_ZNF384-rearranged_ALL_ZNF384	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12375500-41388_2025_3449_MOESM1_ESM.xlsx-DBP_up-gene_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
Intervertebral disc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.097
BRD-K82784817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5864
BRD-K44675576	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07029
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2395
GSE193402_0_v_3_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Extracellular matrix	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
LD-69-ZV56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.222514
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7036
BRD-K39419290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83164
7164_RBM22_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.634157
BRD-K45091989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03755
GSE57871_6_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE233647_4_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE214382,GSE214383_1_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.6316
Meibomian gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.503
BRD-K15620114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.66558
BRD-A52794651	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00879
CRCGN017_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.25377
GSE147366_1_v_0_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K15930345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34572
GSE182680,GSE182683_0_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE190864,GSE190907_1_v_0_cacybp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K51490301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42037
GSE197571_3_v_1_foxm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12410147-NIHMS2099518-supplement-3.xlsx-z-scores_DEGs_DGATi_LPS_vs_LPS-Z-scores_for_genes_differentially_expressed_when_comparing_DGATi_LPS_treatment_to_LPS_alone_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CRK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20091
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.0668
Mucin granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.642
ETV5::HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.0297
3537_GRINA_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.620436
BRD-K01083922	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31701
BRD-A22089150	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28464
GSE174498,GSE174500_0_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
phospholipid dephosphorylation	GO Biological Process Annotations 2025	1.0	null
GSE136232,GSE136234_0_v_1_zpbp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE57871_5_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K20068050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36829
Hallux	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.502
EIF3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55363
BRD-K63665694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17399
BRD-A42536341	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04565
7754_SEC62_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.872431
GSE221327_4_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE221327_1_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE246053_1_v_3_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE48812_4_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
Synovial cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE152441,GSE152442_0_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K73695595	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34677
GSE223893_1_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Synovial tissue	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KATNBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37009
Synoviocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.901
BRD-K62018188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68039
GET4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85759
GSE142210_9_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE120413,GSE120447_0_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
laminin-14 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.775
PMC8185471-mmc4.xlsx-D4-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_4_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
POLA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15963
BRD-K58977196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69229
Limb bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.648
Cervical spine	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.919
MRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18944
Conjunctiva	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.585
7164_RBM22_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.748918
TEX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19526
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.233141
BRD-K61206648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.70323
GSE238018_1_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
lat1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.803
Tunica intima vasorum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.821
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0479
NNAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45485
GSE214212_2_v_1_chd6_human	RummaGEO Gene Perturbation Signatures	1.0	null
6539_POLR1E_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.655277
PMC10925000-12885_2024_12075_MOESM2_ESM.pdf-11-PURG_PURG	Rummagene Transcription Factor Associations 2026	1.0	null
GSE252864_0_v_3_smad4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
l45	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.816
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9092
Germinal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.207
REST	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.2922
Tendon sheath	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE127261_1_v_2_ezh2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.5913
GSE152441,GSE152442_1_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K60068268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08616
light-harvesting complex, peripheral complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.719
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2877
ATXN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01943
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0984
BRD-K13543055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7364
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0455
ATP5MJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14991
DDOST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25617
GSE201309_4_v_2_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
4208_ISG20L2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.517372
Capillary pericyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.611
GSE195568_1_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE206226_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Urine	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
6446_PLEKHJ1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.89208
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	59.3545
CRCGN016_MCF10A.TP53.M_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.72572
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.701
MYOZ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3112
GSE87412,GSE92423_3_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE111247_14_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K56868780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16721
BRD-A69950438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13123
GSE178714_1_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142684_2_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cul2-RING ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.565
MDM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80878
GSE239578_1_v_7_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K90951880	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49412
GSE147626_3_v_1_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K78676275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07674
GSE74383_2_v_3_ror2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6178
GSE169205_3_v_2_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
SNX17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15886
CRCGN017_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.38787
BRD-K57035236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72001
4152_INTS7_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.18498
GSE234289_5_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF692	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.356
RFC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71087
PMC11732233-mmc1.pdf-151-VDR_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE115542_5_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pancreas	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.734306
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	138.972
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.1162
BRD-K97682096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10785
GSE106661,GSE106665_2_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE182179_0_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE48812_8_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
Tear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.683
GSE160001,GSE160670_0_v_2_lapatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TRAPPC6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5429
NOCT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19105
BRD-K82409466	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0384
GSE178714_1_v_4_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K75807957	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70276
BRD-K90694955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07918
BRD-K80166820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87697
BRD-K51175229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.2851
Bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.494
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.117
GSE226114,GSE226116_2_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203364
GSE148066,GSE157787_0_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RTBDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18558
BRD-K90155857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84535
SMAD5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7817
HOXC10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0559
4651_LRP8_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.645962
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.444
BRD-K54151058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.61575
SPTAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45463
GSE193258,GSE193259_2_v_4_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50997
BRD-A38066207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80494
GSE135030_11_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K30071505	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40276
GSE158182_4_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K87126326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61667
GSE130246_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PPP6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91081
GSE168918_1_v_0_tmprss4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE190186,GSE190188_0_v_10_apoe_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5433
BRD-K46334103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30348
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4582
GSE96641_1_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
9682_UTP15_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.591348
GSE158834_1_v_6_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
HSPA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31507
BRD-K54079231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2647
GSE71468,GSE76476_2_v_3_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE206729_2_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE248858_4_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Human amniotic epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.583
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2351
Rheumatoid arthritis disease specific synovial tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.81
PMC9537523-41467_2022_33364_MOESM7_ESM.xlsx-scores_wilcoxon_1_MONTH_ORG-EN2_n_EN2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE130715_2_v_3_budesonide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE106661,GSE106665_0_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.5833
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-4_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE221327_1_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
RHOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13072
BRD-K10494344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85609
GSE130715_2_v_0_budesonide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Activin AB complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.632
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0794
Skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.871
PMC10251551-12885_2023_11010_MOESM4_ESM.pdf-41-KLF5_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE193900,GSE193905_1_v_0_pura_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE143944_2_v_3_ribociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE142210_3_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K69082321	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50761
CRCGN016_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.95339
CRCGN014_HEPG2_24H:N12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.82075
BRD-K02361314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99998
GSE199204,GSE211619_4_v_0_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K99038919	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07608
Six3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.0746
GSE152055_0_v_1_mpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE128730_0_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF148	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	128.398
Synovial fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.549
GSE235550_1_v_0_hspa9_human	RummaGEO Gene Perturbation Signatures	1.0	null
2561_EIF4A3_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.644856
7438_RPL14_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.545517
Chondroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.343
BRD-K06486611	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20509
KLF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	122.066
GSE153137,GSE153140_2_v_1_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Adipose - Subcutaneous	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.71251
6581_POT1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.654777
BRD-K22280519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72792
HLMVEC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.575
Intraparietal sulcus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.571
APTX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33511
BRD-K56563145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42703
lipid phosphatase activity	GO Molecular Function Annotations 2025	1.0	null
Forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Biceps	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.904
TSC22D4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21047
CCZ1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68438
GSE225901_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K76420749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04486
GSE166315_5_v_3_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K89324382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.42925
BRD-K53274037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80988
GSE141624_3_v_0_cocaine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K92167240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98976
BRD-K74109014	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77186
GSE101112_0_v_4_j147_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A14842104	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06516
GSE142210_9_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Connective tissue	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE130246_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_7_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE48812_3_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE221327_4_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Sternum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.109
Vitreous chamber of the eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.918
GSE74251_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Exoskeleton	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.744
Integrin alpha9-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.641
GSE134375_3_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Dermal fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.286
2495_EFHD1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.619097
GSE200982_0_v_2_plac8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE217405_3_v_2_osimertinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE229070,GSE229071_0_v_2_sotorasib_human	RummaGEO Drug Perturbation Signatures	1.0	null
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.8176
GSE121198,GSE129779_3_v_2_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
vacuole-isolation membrane contact site	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.641
GSE171572_3_v_4_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
Mandibular condyle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.198
Nanog	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.2271
2105_DDX18_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.777693
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.1017
PMC4266008-mmc3.xlsx-iPS-MSC_vs_MSC-Unnamed_24_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Fascia	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.343
Mesenchymal stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.233
GSE161864,GSE161866_4_v_3_ror2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2534
ZNF135	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.1382
Articular cartilage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.444
GSE226091,GSE226092_3_v_1_sall1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K72675584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30678
TBL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09733
CRCGN013_HEPG2_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17754
ZNF547	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2403
GSE199204,GSE211619_4_v_1_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE224311_3_v_4_chaetocin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE183251_1_v_3_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE109140_2_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC12518476-10067_2025_7574_MOESM8_ESM.xlsx-Sheet1-Up_regulated_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE195568_1_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE205163,GSE205164_1_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.8839
GSE221327_4_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE223008_5_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE163297_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Keratocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.734
964_C12ORF45_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.532077
BRD-K80210288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02646
BRD-K52416366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71444
PUM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46478
BRD-K48235506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41413
2790_EXOSC3_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.550101
Signaling by GPCR	Reactome Pathways 2024	1.0	null
CRCGN017_MCF10A.TP53.M_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.57578
GSE232624_4_v_5_ethanol_human	RummaGEO Drug Perturbation Signatures	1.0	null
ANAPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33777
BRD-K75672292	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30405
BRD-K83466873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94531
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.288305
Atf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.7039
PMC4909989-ncomms11840-s2.xlsx-down-regulate-TEAD4-S_YAP_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K03353688	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59238
GSE194396,GSE194429_1_v_0_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
Eyelid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.683
GSE210682_0_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7299226__F6	PFOCR Pathway Figure Associations 2024	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K18136154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57235
GSE57871_5_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN013_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.45175
CSPG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24644
GSE162688_1_v_2_pink1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
7565_RRP36_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.513807
GATA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1039
ADSS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00886
BRD-K90562751	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.35202
Heparanase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.755
MCF7_Linifanib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0156977
BRD-K79232672	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26521
early-onset Parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.141
SGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32608
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K64451677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61932
GSE201309_4_v_7_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K99525048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42626
BRD-K24246830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74191
Tenocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.233
BRD-K88636226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82481
GSE180200,GSE180201_5_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE92364_0_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE102870_3_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE236262_0_v_3_trim28_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DPPA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17027
GSE242083,GSE242098_3_v_4_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.4019
PMC9974104-jci-133-159940-s019.xlsx-GT3-INCP-GATA3_co-bound_genes-Gene_Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K45964657	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43055
GSE118617,GSE118619_2_v_3_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN010_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.48313
GSE205976,GSE205978_3_v_5_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K58066822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.23086
GSE236454,GSE236456_0_v_1_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE157555,GSE157556_4_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158834_10_v_6_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8972
MCF7_RG108_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.022946
GSE200352_5_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE175787_5_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE164874_5_v_2_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
8458_SSRP1_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.41627
PMC5013636-ncomms12601-s5.xlsx-SP1-Groups_SP1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE206502_2_v_1_igf2bp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A15086915	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03899
Temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FUCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75458
GRPEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37587
GSE160817_4_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE175787_8_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE193258,GSE193259_2_v_8_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K24396618	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50427
GSE152441,GSE152442_0_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Chondrogenic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.147
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	49.5388
GSE142210_2_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CCDC174	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35117
CRCGN017_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.93589
GSE240027,GSE240030_1_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE110178_1_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE249404_0_v_1_oxytocin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Marrow	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.582
PMC10771438-41598_2023_51082_MOESM1_ESM.xlsx-Day21-Supplementary_Dataset_1_List_of_genes_differentially_expressed_during_NS_PC_differentiation_between_ROR2_KD_cells_and_control_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A96007399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32753
GSE164874_5_v_10_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE241622_1_v_0_ythdc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
7439_RPL15_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.663637
GSE158431_2_v_3_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC3435504-msb201237-s2.xls-Supp_Table_4a-SP1_SP1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K92460921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.16236
Talus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.838
BRD-K00631971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39661
GSE149075_3_v_11_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.908
GSE241701_1_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TKFC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18869
BRD-K36134264	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03785
GSE202603_0_v_2_bhlhe40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HLF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13632
BRD-K11247495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57265
GSE120612_7_v_3_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE140965_1_v_4_mybpc3_human	RummaGEO Gene Perturbation Signatures	1.0	null
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1895
DAB2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40187
GSE169334,GSE169336_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K57167256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01375
Pectoral fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.86
GSE235066_4_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE119498_2_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE181003_3_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE216273,GSE216292_0_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE130246_1_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PLXNA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25663
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.9143
SMIM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16423
GSE146612_2_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-8_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K24025166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06732
VCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5716
GSE242555_1_v_0_fn3k_human	RummaGEO Gene Perturbation Signatures	1.0	null
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.5457
GSE192663_1_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3294
PMC12753515-Table2.XLSX-G5-specific_down_only_top_500-EGR2_EGR2	Rummagene Transcription Factor Associations 2026	1.0	null
NFILZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28381
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6381
PMC9546828-41389_2022_435_MOESM4_ESM.xlsx-Table_S3-Table_S3_Downregulated_genes_upon_ZNF148_knockdown_P_adj_0_05_Fold_change_1_5_ZNF148	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A78355490	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09046
GSE135312_1_v_2_bmpr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Subcutaneous tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.891
chr19_11336355_A_C_b38	GTEx eQTL 2025	1.0	1.20746
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6219
GSE164757,GSE164759_4_v_0_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE148200_3_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K57443386	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46731
GSE81803,GSE81912_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bone marrow stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.095
CRCGN015_MCF10A.TP53.M_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3027
GSE221327_1_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2416
CEBPB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.036
GSE182181_1_v_0_ricolinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Breast carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.143
PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-NT_Fig1c-Gene_Symbol_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K39140255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32961
GSE242083,GSE242098_3_v_1_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE101112_6_v_4_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE232631_5_v_2_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Epiphysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.708
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.8439
GSE147876,GSE147877_4_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6811834-sby183_suppl_supplementary_data_set_1.xls-ZNF804A_DEX_FDR_0_01-Gene_Symbol_ZNF804A	Rummagene Transcription Factor Associations 2026	1.0	null
LN-215 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.103
GSE221327_4_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE108495_1_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K63864604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12265
Hindlimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.686
ZNF358	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94537
BRD-K90003650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01746
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.978
BRD-K88369626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.21166
Osseous plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.863
procollagen-proline 4-dioxygenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.566
GSE128730_7_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
6283_PHF19_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.623097
GSE239844_4_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE203485_1_v_0_sunitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-9_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
Temporomandibular joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.426
BRD-K53706972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45825
BRD-A07944983	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19605
BRD-K49707067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29081
GSE142210_3_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8792
ATP5MGL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12852
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.0
GSE80446_0_v_1_anakinra_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.8559
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.2963
Plagl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.7237
GSE233679_6_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6818
Mpf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.533
BRD-K74665927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08342
4945_MED22_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.507478
GSE164874_5_v_7_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.06086
Annulus fibrosus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.862
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8509
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.3995
BRD-K11010670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12788
GSE196104,GSE196106_2_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K96549574	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1328
PAT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.789
BRD-K33757887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25829
GSE121866_0_v_3_six4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
R3HCC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1328
GSE154577_7_v_10_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11067031-pnas.2317690121.sd03.xlsx-gene_list_-_2022-04-13T081711_1-Differentially_expressed_genes_between_PML_RARA_GFP_vs_Empty_vector_GFP_mouse_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K46942548	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65237
GSE228181_3_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K77354700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23581
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.6235
CRCGN012_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.61844
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5802
BRD-K61189585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55889
Stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.039
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.6098
GSE221327_10_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K01605333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2688
T3M-10	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.978
CRCGN016_MCF10A.WT.HP_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.79298
SP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.2535
MCF7_ITSA-1_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0118153
lipid modification	GO Biological Process Annotations 2025	1.0	null
BRD-K03953354	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34424
BRD-K60057192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15355
Fascicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.962
8331_SPC24_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.547896
GSE226584,GSE226589_1_v_0_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2347
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4246
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6099
GSE149000_2_v_0_cyp3a5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Ikzf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.4937
BRD-K17285234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00688
CSTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12015
PMC9270251-mmc2.xlsx-2_Filtered_DEGs_Control_vs_KD_2-Gene_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Periodontium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.349
GSE62843,GSE64370_0_v_1_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.8109
Cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K60107240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6034
ZEB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59517
GSE207135_1_v_0_sod2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12619835-41467_2025_66007_MOESM12_ESM.xlsx-KLF5_activated_H3K27ac_T3M4-Nearest_Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE199204,GSE211619_4_v_6_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Heart valve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.867
Lung microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.533
BRD-K71298594	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.55527
GSE160817_5_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EMILIN complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.154
3916_HOXC6_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.531996
GSE205630_0_v_1_gmds_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K81568980	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96839
PMC3435504-msb201237-s2.xls-Supp_Table_4a-WT1_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K46120925	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.4884
BRD-K06392309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60714
BRD-K87340219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27049
ENG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70636
GSE175787_8_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KLF17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.5992
GSE240645_3_v_2_u90926_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.8812
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.3102
Leg	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.721
N1E-115 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.602
ZNF883	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20165
GSE228992_0_v_1_mafb_human	RummaGEO Gene Perturbation Signatures	1.0	null
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.6011
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44733
Collagen sheet	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.829
7389_RNF34_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.525914
GSE199660_1_v_0_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
EIF4A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98056
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3988
BRD-K50315405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06085
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	99.2465
Arterial blood cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.035
GSE238116_1_v_0_egr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.9458
DYNLRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03039
BRD-K85636571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27294
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	84.0931
t60-adrenal_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	3.02954
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.8523
GSE158834_11_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Dlx5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.8438
PMC3435504-msb201237-s2.xls-Supp_Table_4b-WT1_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE166315_1_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE185519_3_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE246053_1_v_2_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.5408
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.437
GSE233183,GSE233187_3_v_9_larp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cheek	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.907
7477_RPL7A_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.898906
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.5761
PMC8384902-mmc6.xlsx-DEG_3TF_KD_unique-GeneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE215351,GSE215794_4_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135514_2_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
4944_MED21_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.853079
GSE195568_6_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE162590_1_v_0_gsx2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Mural cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.074
GSE165122_2_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Osteoclast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.868
Breast - Mammary Tissue	GTEx Tissue Gene Expression Profiles 2023	1.0	2.47518
GSE95077_5_v_2_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE213153_1_v_0_ulixertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE210101,GSE210114_8_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4407272-elife06857s002.xlsx-501M_BRG1-MITF_ComUP-List-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE221327_5_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
CHAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22359
GSE228181_3_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K18637162	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11856
GSE97352_1_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8527
RBM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36586
GSE211215_1_v_0_pemetrexed_human	RummaGEO Drug Perturbation Signatures	1.0	null
Bone matrix	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.61
GSE210885_5_v_7_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Longissimus thoracis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.937
GSE158834_11_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
SLC24A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4511
Molybdopterin cofactor (Moco) biosynthesis adenylyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.08
GPCR ligand binding	Reactome Pathways 2024	1.0	null
BRD-K20661169	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70288
BRD-K83477969	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0581
BRD-K57184137	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13661
Thoracic cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.143
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9022
GSE144231_2_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K58753007	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44752
Hip joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.946
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.9964
MCF7_Dacinostat_1µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00729578
GSE221327_6_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Clozapine-induced cytotoxicity	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
BRD-K76980944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34945
BRD-K46085646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30022
BRD-K61753872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01051
BRD-K84334677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73843
GSE174498,GSE174500_5_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K51858914	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78523
7463_RPL35_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.519391
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.8733
LSG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25088
GSE195559_2_v_7_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K13898728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.11329
8651_TAF10_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.897232
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.6689
Integrin alpha5-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.971
GSE162892_4_v_2_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.294
3220_FUNDC2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.547737
Collagen trimer	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.029
GSE175787_4_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.6864
BRD-K33897007	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17558
GSE111660_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216273,GSE216292_14_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158431_5_v_7_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
6795_PRPF38B_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.697419
GSE167886_2_v_0_chd7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GLO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89491
TOMM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22339
PMC3226433-1756-8935-4-20-S1.XLS-Table_S4_Myc_KD_gene_exp_change-Genes_up-regulated_in_Myc_KD_hESC_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Tenascin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.352
GSE152441,GSE152442_6_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.4315
BRD-K49525275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50613
GSE81803,GSE81912_0_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.3327
BRD-K45022385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41914
Cytoneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.685
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4662
PMC12619835-41467_2025_66007_MOESM13_ESM.xlsx-Sheet1-AsPC1_KLF5_activated_H3K27ac_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
Mandibular ramus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.163
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4651
GSE235066_4_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Chondrosarcoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.179
BRD-K01358985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75987
BRD-K03116744	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.4836
BRD-K66559139	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14451
GSE70935_2_v_4_cyfip1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K75275329	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1492
GSE184210_0_v_3_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF460	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	126.843
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9188
GSE207135_2_v_0_sod2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8040704-jcav12p2673s2.xlsx-Down-regulated_genes_in_EBF1-Unnamed_0_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K72890304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15545
BRD-K80546581	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03594
BRD-K57357721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59219
Osteophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.569
AP1M2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4307
GSE162892_4_v_2_sox9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
8271_SON_P1	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.02846
GSE205316,GSE205317_2_v_3_nrip1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
collagen-containing extracellular matrix	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GSE169205_0_v_6_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
1860_CREB3L3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.878303
CENPM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01527
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0272
BRD-K96069147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32926
BRD-K63957636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6727
BRD-K44833533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07109
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.4286
PCDHB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15757
GSE221327_5_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Adipose tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.015
PMC4595011-pgen.1005555.s003.xlsx-BPTF_UP-regulated-Gene_name_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-19q13_43_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
Primary dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.569
BRD-K11307720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24505
Muscle tendon junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.496
BRD-K00191683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06352
GSE228727_2_v_0_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Endochondral bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.91
BRD-K19045069	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84599
Hinge joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.636
CRCGN011_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25805
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.881
BRD-K30025024	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52488
GSE235701,GSE261434_0_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_24H:M14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00548
Brain - Nucleus accumbens (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.707177
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.017
BHLHA15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.689
GSE195568_3_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE147876,GSE147877_4_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE88819_3_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K56126872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.29854
GSE132369,GSE132371_3_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.616
Cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K18454119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30765
BRD-K41116634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43184
GSE126127_0_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.8918
CRCGN017_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9495
BRD-K27384243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30078
Biceps femoris	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.557
5550_NDUFAF7_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.542578
BRD-K37331547	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4314
PMC4686761-ncomms10068-s3.xlsx-S2E-MSC_up_specific-Supplementary_Data_2E_-_expression_of_up-regulated_genes_2_fold_change_specifically_in_MSC_PTEN-_-_vs_MSC_PTEN_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K74382273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02736
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	87.2841
GSE167886_2_v_1_chd7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
6868_PSMD14_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.01376
BRD-K86208187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35779
GSE205163,GSE205164_2_v_0_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE242083,GSE242098_2_v_1_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10243915-uxad037_suppl_supplementary_table_s1b-table_s3b.pdf-180-BHLHA15_BHLHA15	Rummagene Transcription Factor Associations 2026	1.0	null
GSE97352_3_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K90060707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84006
PMC12518476-10067_2025_7574_MOESM9_ESM.xlsx-Sheet2-RNAseq_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE110524_2_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
KLF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.4223
CRCGN008_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.43272
Blood	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
6902_PTCD3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.508699
GSE233183,GSE233187_2_v_9_larp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE233679_6_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE146612_1_v_3_amiodarone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03095
GSE111660_1_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ETV4_ETV4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K87812655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07926
GSE221327_6_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K44944875	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91803
Integrin alpha10-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.363
GSE144231_2_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K73463737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.7964
GSE122101,GSE122103_3_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE179880_1_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Connective tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.015
Central cylinder	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.8
BRD-K64730221	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53663
GSE181513_2_v_1_usp7_human	RummaGEO Gene Perturbation Signatures	1.0	null
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9356
GSE77108_8_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
Epiglottis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.786
GSE95685_2_v_5_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SOX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2237
GSE213588_8_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-6_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE182179_2_v_4_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DCTN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77771
Carotid atherosclerotic plaque	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.76
BRD-K94427708	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.22795
GSE168401_1_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
2225_UTP25_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.41642
BRD-K97247086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51242
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9305
GSE210093_3_v_2_taf15_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K05001008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04216
Latex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.445
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-7_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
chr19_11321225_G_A_b38	GTEx eQTL 2025	1.0	3.39695
GSE227127_1_v_0_diclofenac_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Corn silk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.529
GSE199204,GSE211619_4_v_7_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE161864,GSE161866_1_v_3_ror2_human	RummaGEO Gene Perturbation Signatures	1.0	null
SFPQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23378
CRCGN016_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.78973
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7955
GSE96649_1_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
TTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35869
GSE162623_0_v_1_ezh2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE128730_3_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Carcass	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.355
CENPJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46544
Flexor tendon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.514
PMC10361959-41419_2023_5985_MOESM1_ESM.pdf-1523-ZNF14_ZNF14	Rummagene Transcription Factor Associations 2026	1.0	null
Jaw	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.804
DDX3Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29103
GSE206226_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE127790_5_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RXRA::VDR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9
BRD-K77782946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.095
GSE182680,GSE182683_0_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.0111
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.6479
GSE157555,GSE157556_0_v_6_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE132408_0_v_3_tet2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE234289_3_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GLIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1241
PMC9894241-pnas.2211429119.sd05.xlsx-G6_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
GSE162892_3_v_0_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE202434,GSE202438_9_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PCGF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06353
Skeletal system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC3906982-1471-2164-14-830-S1.xlsx-Sheet1-Table_S1_HOXC9-responsive_genes_HOXC9	Rummagene Transcription Factor Associations 2026	1.0	null
GSE131649_6_v_9_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3182
Mesenchyme	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.977
6536_POLR1C_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.556103
FLNC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75374
GSE169205_4_v_7_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
4957_MED7_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.628491
GSE79663_2_v_0_tcf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Mesenchymal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.717
BRD-K67131822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73226
NUP54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04656
GSE153189_2_v_3_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE172016_2_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF816	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.0133
GSE154577_2_v_9_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K71452126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50779
ZNF708	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3357
GSE161295_2_v_3_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K03549232	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12213
GSE201309_4_v_6_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2J	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65631
GSE199606_5_v_4_csf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9424213-41467_2022_32537_MOESM6_ESM.xlsx-siHNRNPK_cyto-DEGs_for_hnRNPK_KD_cytoplasmic_RNA_of_HeLa_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE232786_1_v_0_otud1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.0314
AQR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37238
Temporomandibular articular disk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.885
BRD-K30065842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.1472
Corpus striatum	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
collagen-containing extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.373
BRD-K98935620	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31059
GSE57871_1_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CEBPE	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0126
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8577
col10	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.112
NUMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80672
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4241
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.298
GSE240027,GSE240030_1_v_3_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K09367542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19063
GSE57871_11_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
KRT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1575
B800-850 antenna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.783
RPS3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46345
GSE178714_1_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.61192
ZNF780A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28186
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.366
BRD-K41620124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.85214
ZBTB24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.3913
GSE135514_8_v_3_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K64827406	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0198
BRD-K04518829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1981
GSE201309_1_v_0_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Laticifer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.445
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.143
PMC12079334-ADVS-12-2501734-s002.pdf-187-ENSG00000196605_ZNF846	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K49872883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58538
Vitreous humor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.935
PMC7606598-NIHMS1624889-supplement-1624889_Supp_Tab1-10.xlsx-S8_MR-JTI-genename_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE182680,GSE182683_7_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE133763_0_v_2_chd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169205_3_v_6_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE217452_3_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K72255288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35216
BRD-K35614154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33643
GSE125014_1_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6672
BRD-K57902040	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37092
GSE135030_3_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE239784_1_v_0_sat1_human	RummaGEO Gene Perturbation Signatures	1.0	null
DDX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55687
CRCGN013_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.92421
Preosteoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.376
GSE195568_3_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SMAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2709
BRD-K47028303	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20768
PMC9270251-mmc2.xlsx-4_Filtered_DEGs_Control_vs_KD_3-Gene_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
DMRTA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4537
GSE96641_5_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ATRIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58331
GSE142210_3_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K59028365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56094
GSE221327_8_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE253089_0_v_1_ephb2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE242555_1_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE214382,GSE214383_0_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Scale	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.566
Rheumatoid arthritis disease specific synovial fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.603
GSE110178_4_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	62.6297
9971_ZBTB14_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.876775
9841_WDR75_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.09234
CRCGN016_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.66975
GSE225869_1_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6894
Nkx3-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.4713
GSE228181_2_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Meniscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.983
Camptodactyly-arthropathy-coxa vara-pericarditis syndrome	ClinVar Gene-Phenotype Associations 2025	1.0	null
BRD-K56801250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39297
PMC8851354-Table_2.xlsx-Genes_reg_by_FUS-DDIT3-Supplementary_Table_2_Genes_significantly_regulated_by_FUS-DDIT3_expression_in_HT1080_cells_adjusted_p-value_0_05_and_log2_Fold_change_1_or_-1_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE200352_1_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3662
Cervix - Ectocervix	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.11271
GSE126127_5_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE48812_4_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF148	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04297
BRD-K65506286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.22435
Synovium	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZBTB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6659
GSE240027,GSE240030_5_v_2_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K17412949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29613
Mesothelioma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.591
3935_HPS5_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.580787
GATA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5833
CRCGN011_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.65693
BRD-K30283890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09429
BRD-K84761515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65717
BRD-K03855997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01701
GSE153189_1_v_3_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1575
GSE158834_0_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pleural cavity	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.822
Brain - Amygdala	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.994459
BRD-K79954583	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41648
GSE183113_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	63.4176
H1-7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30565
GSE188382_4_v_0_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Fc-gamma receptor I complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.741
BRD-K78741913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33473
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4897
Cornea	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.749
CRCGN017_MCF10A.WT.HP_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.95617
BRD-K03875473	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47092
GTPase activator complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.656
BRD-K01910220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6592
VPS36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14282
GSE246053_4_v_3_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE57871_5_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	143.083
Amygdala	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K85580909	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25864
GSE87412,GSE92423_0_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.81
4939_MED17_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.661473
CRCGN017_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.74614
BRD-K03506285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48506
BRD-K81082552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72445
Vertebral endplate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.015
GSE140607_0_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE163297_0_v_2_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3709
CRCGN008_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.65057
Metatarsal bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.172
Six4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.1347
GSE216273,GSE216292_14_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
adipose-derived stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.38
Breast cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.143
Breast disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.143
Tibialis posterior	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.815
BRD-K37283718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.13748
BRD-K66453893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45095
GSE172494_3_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Forelimb muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.844
CRCGN014_HEPG2_24H:M15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.29645
GSE233183,GSE233187_2_v_6_larp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TRAPPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52696
BRD-K37308886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.64463
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.2159
BRD-K36643302	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50675
BRD-A57594599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05512
BRD-K36697652	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12749
BRD-K80733946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43606
Gingiva	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.143
BRD-K32918816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09145
External encapsulating structure	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.801
GSE207433_2_v_3_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE151612_4_v_2_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE256181_2_v_3_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158182_4_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE143782_3_v_4_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K42253676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21878
GSE252857_2_v_3_prednisone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
p2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.91
GSE158834_1_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	104.372
3042_FCF1_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.03937
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	60.7956
GSE189859,GSE189861_4_v_2_idh1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE190384,GSE190386_1_v_8_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Collagen network	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.322
BRD-K28601178	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.21948
GSE121866_0_v_2_six4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.0133
Corneal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.449
GSE172020_0_v_2_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE57871_1_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
KLHL31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01753
SAYSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06998
CREB3L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19238
GSE152441,GSE152442_0_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K32063762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24713
BRD-K86288396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0631
BRD-A04618830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02008
L-cysteine desulfurase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.938
NFIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57125
PMC11908325-media-2.xlsx-Table10_MR-Unnamed_6_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE113734_3_v_2_qprt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K96945047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.61274
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3555
GSE175787_11_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213650_3_v_1_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE136894_1_v_0_psen1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Peribronchial gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.504
PMC8812561-pnas.2110428119.sd11.xlsx-Sheet1-The_overlapping_genes_of_LCDR_KD_RNA-seq_hnRNP_K_KD_RNA-seq_hnRNP_K_RIP-seq_and_eCLIP-seq_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Deep fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.557
GSE162892_3_v_1_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
Conjunctival epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.525
GSE258991_5_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K51185182	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16282
GSE145915_3_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10251551-12885_2023_11010_MOESM4_ESM.pdf-41-ENSG00000102554_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
fibroblast-like synoviocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.406
Endolysosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.671
BRD-K57202089	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.18582
BRD-K24081812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.808
PMC12518476-10067_2025_7574_MOESM9_ESM.xlsx-Sheet2-intersection_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6242972-41467_2018_6699_MOESM5_ESM.xlsx-Sheet1-Supplementary_Data_2_Significantly_up-_and_down-regulated_genes_adj_P_Val_0_05_upon_TBX2_knockdown_in_the_IMR-5_75_cell_line_TBX2	Rummagene Transcription Factor Associations 2026	1.0	null
TWIST1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1571
Flexor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.654
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.52
BRD-K61553906	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49481
Caudate nucleus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE221327_8_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.967
GSE160817_5_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K09511124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16289
Brain - Spinal cord (cervical c-1)	GTEx Tissue Gene Expression Profiles 2023	1.0	1.49856
BRD-K08476323	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25814
GSE216352,GSE216354_1_v_0_keap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K37616496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90241
BRD-K93567937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40867
BRD-K17133642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02783
GSE138945,GSE138947_0_v_1_mboat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE226115,GSE226116_2_v_0_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE213746_0_v_1_kdm5b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
7516_RPS27A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.685408
GSE158182_5_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
sheet-forming collagen trimer	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.742
GSE134615_1_v_0_lats1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LIMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39523
BRD-K58245454	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40931
BRD-K98020844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13339
BRD-K61772027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18727
4758_MAGEA12_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.717355
BRD-A08363225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40141
GSE175787_8_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TEKT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20279
CCDC152	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61193
2988_FBL_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.697182
BRD-K20440082	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42333
Telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Flexor digitorum profundus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.18
BRD-K31559225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69656
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3652
GSE213588_8_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7606598-NIHMS1624889-supplement-1624889_Supp_Tab1-10.xlsx-S8_MR-JTI-geneid_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE95077_5_v_3_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE95688_7_v_2_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE138633_2_v_0_bag3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE92457_7_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE201309_5_v_0_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K68083867	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17403
MGA::EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8953
UQCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0876
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.9802
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5301
GSE157555,GSE157556_3_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.202813
Fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.313
CRCGN017_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.63377
ATDC-5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.98
GSE160817_4_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PPP1R7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85098
GSE205976,GSE205978_2_v_5_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE164757,GSE164759_4_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE224877_2_v_1_pctp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A10417568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13541
Dental pulp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.002
Disc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.619
BRD-A63503250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15377
GSE225869_1_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K75648723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27145
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.7592
KIF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49355
GSE48812_8_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE118548_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K28488100	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48689
GSE158431_2_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K95941120	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26106
GSE216273,GSE216292_14_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE166315_5_v_4_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Glottis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.571
BRD-K26552461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67982
GSE199660_1_v_3_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K35693854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71905
BRD-K42126155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30216
GSE74251_2_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SW-1353 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.157
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7844
BRD-K52406139	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45623
ADAM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23644
CRCGN016_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.90317
MED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0243
Hypertension	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.701
901_BRIX1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.653903
Foxo3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.8791
GSE87412,GSE92423_2_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE218580_1_v_5_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
9444_TWSG1_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.17362
GSE153836_11_v_9_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE135030_8_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K66748326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43921
l23	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.727
GSE152432_3_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K39710695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45445
Chondroma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.654
Galectin lattice	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.763
GSE189772,GSE189773_3_v_2_fbxo11_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN009_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.86978
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9891
GSE215849_2_v_1_muc1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K57497543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36374
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE85880,GSE85881_0_v_1_tretinoin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Abductor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.638
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1573
Wrc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.134
PMC12619835-41467_2025_66007_MOESM12_ESM.xlsx-KLF5_activated_H3K27ac_AsPC1-Nearest_Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE119498_0_v_5_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Crop	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.885
GSE179880_7_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE229973_4_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE185519_1_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZKSCAN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.4143
Fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.048
GSE169713,GSE169715_3_v_2_tert_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Notochord	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.229
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.5249
BRD-K81266242	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12694
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.5055
Granulation tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.897
6793_PRPF31_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.713499
CRCGN013_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.01297
Myosin X complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.728
GSE188869,GSE188871_1_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K29636267	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26413
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.7477
GSE181959_1_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Artery disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.701
RSL1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43208
BRD-K63145472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24957
GSE210101,GSE210114_2_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169205_0_v_1_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE217132_0_v_1_pfkfb4_human	RummaGEO Gene Perturbation Signatures	1.0	null
LAMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54644
BRD-K81801123	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.22227
Callus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.258
6537_POLR1D_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.09344
Cranium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.0
Microfibril	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.772
Calvarium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.257
ZGPAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10534
BRD-K92803674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52227
GSE195568_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	95.0672
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.6339
GSE228181_2_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN013_HEPG2_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.25666
GSE199660_1_v_2_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K47673408	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.29881
BRD-K76515685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48063
Periosteum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.207
GSE225735_1_v_4_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Stomach	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.664282
GSE157684,GSE173391_0_v_1_rgcc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE94849_7_v_0_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6607928-iovs-60-07-32_file_S11.xlsx-no_change_NRL_mutants-human_gene_ortholog_NRL	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K83139520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25964
BRD-K84115096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62214
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K76588894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07902
BRD-K43206373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05071
MCF7_Belinostat_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00696904
HSPA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32775
BRD-K98758203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35323
Nfatc1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.5697
BRD-K48592348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.384
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.4972
3677_HEATR1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.545993
GSE206729_4_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
4947_MED24_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.502979
BRD-A06471483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.56401
GSE153836_14_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K86925685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93293
GSE193351_1_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE200430_1_v_0_sema3d_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K50942788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54893
CTNNBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30021
PET complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.516
Thoracic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.143
BRD-K88543505	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.51052
GSE154577_2_v_10_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K63493628	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37102
2930_SINHCAF_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.515825
dephosphorylation	GO Biological Process Annotations 2025	1.0	null
Vertebra	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.483
CTCFL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.1453
PMC8224457-MSB-17-e9760-s005.xlsx-C_Ctrl_v_HMGB1-KD_IMR90-Gene_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Smc5-Smc6 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.833
BRD-K39794286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08802
BRD-K81586131	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97764
BRD-K73114074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03588
Colon - Transverse	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.17856
BRD-K54143708	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2996
NR2C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.957
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.4
BRD-K81884775	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21698
GSE157555,GSE157556_5_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE57871_11_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
874_BOP1_P1	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.544461
HRH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32546
RNA-directed RNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.901
GSE161295_0_v_1_cdk8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE118077_7_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
OLIG3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3729
BRD-K95153342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.30099
PGR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4692
GSE147662_2_v_5_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K32782599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38958
CRCGN009_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.41602
GSE121198,GSE129779_3_v_1_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE126345_2_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4595011-pgen.1005555.s003.xlsx-MITF_UP-regulated-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE201309_1_v_2_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5593
GSE48812_7_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE214335_1_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE174498,GSE174500_2_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
S100A8 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.452
HDAC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77651
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_downreg-mouse_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K74150320	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03378
BRD-K64451058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12076
GSE253795_1_v_0_alkbh5_human	RummaGEO Gene Perturbation Signatures	1.0	null
cone-rod dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.248
platelet-derived growth factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.0
BRD-K74522958	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23335
Basal ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE220914_1_v_0_zdhhc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Blood microparticle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.705
BRD-K66032509	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46042
1200_KNL1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.511934
Zfp809	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.815
GSE221327_6_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE183251_4_v_6_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE93674_2_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE137818_5_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE252857_2_v_3_klf15_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
interleukin-1 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.137
NEPRO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1491
GSE111247_2_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE100102_0_v_6_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nucleus pulposus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.828
GSE149096_4_v_3_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
3054_FECH_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.09019
Internal capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.705
GSE48812_7_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.3103
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.447
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1973
GSE101767_1_v_0_wdr11_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE134214_0_v_1_ell2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE48812_3_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_GSK1070916_1µM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0112656
PMC11769988-Table1.xlsx-Table_S3-Table_S3_SCLC-related_genes_screened_by_MR_analyses_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
2869_FAM161A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.520578
Longissimus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.871
GSE125014_6_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K18402224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.31395
BRD-K16228393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33567
BRD-K61316494	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34768
CRCGN016_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.78638
ERCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63457
BRD-K81925504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52618
BRD-K84663394	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22818
GLIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.2382
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.6381
496100412_FWM_possible Alzheimer's disease_TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21432
4957_MED7_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.825582
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1803
GSE216043_10_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1955
GSE128730_0_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE249714_0_v_1_anxa1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FNIP-folliculin RagC/D GAP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.748
BRD-K78643409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5585
BARHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5029
BRD-K53104784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01996
HEK-293H cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.483
BHLHE23	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3157
BRD-K92884779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1635
CRCGN015_MCF10A.TP53.M_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.67343
BRD-K81706364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58008
BRD-K90103008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40398
GSE48812_3_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE216273,GSE216292_0_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.9234
PPIL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36765
SLC35E2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08733
GSE157555,GSE157556_0_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE128844_0_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K32856496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24822
GPN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07985
Pericardial fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.066
GSE248770_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4387
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.2275
GSE134375_4_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9843885-40478_2023_1507_MOESM6_ESM.xlsx-CIC-OE_TS603-Unnamed_1_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE221327_10_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN012_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.75446
GSE160817_5_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Fibula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.303
PMC7825356-8844261.f3.docx-182-ZNF562_ZNF562	Rummagene Transcription Factor Associations 2026	1.0	null
GSE201309_1_v_6_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE140607_5_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PITX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78024
GSE109140_2_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hmx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.7658
GSE152441,GSE152442_1_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.0795
BRD-K45986774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72513
BRD-K49461735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72266
BRD-K17514980	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1824
Anchoring collagen complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.083
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
GSE206729_2_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE234289_5_v_0_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K84690141	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92349
GSE190384,GSE190386_2_v_8_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE71468,GSE76476_0_v_3_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7029036-41598_2020_59469_MOESM2_ESM.xlsx-NR4A1_Targetome-Genes_NR4A1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K30792491	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01288
GSE106170_1_v_0_nap1l3_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.29373
BRD-K75990394	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83045
BRD-K87878529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26936
CDHR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68322
BRD-K87602457	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12746
BRD-K91885806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33506
phospholipid metabolic process	GO Biological Process Annotations 2025	1.0	null
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2604
GSE57871_1_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K20724649	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28059
Adult stem cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.133
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.708
GSE234514,GSE234516_1_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Sclera	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.998
ESR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.856
PMC8567138-Table_2.xlsx-Sheet1-IGFBP5_AND_IGFBP7_NOT_IGFBP3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
Tendon sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.047
GSE162892_4_v_5_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perichondrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.265
GSE256181_2_v_0_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Glycocalyx	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.662
BRD-K64698855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24919
Synovial tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.035
GSE225901_2_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K74988798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4264
BRD-K30312557	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06672
Holocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.656
BRD-K61034310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52672
GSE152441,GSE152442_6_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE48812_9_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11908325-media-2.xlsx-Table10_MR-Unnamed_7_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXP4_FOXP4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE233183,GSE233187_3_v_6_larp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PTPN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18521
GSE201657_0_v_1_ash2l_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE191015_0_v_2_gsdmb_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE238018_1_v_0_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE48812_4_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN012_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.07344
GSE129389_0_v_6_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-5_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE112761,GSE112767_2_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE73561,GSE73563_0_v_1_mef2c_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
insulin-like growth factor binding protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.02
BRD-K79684522	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02304
GSE70935_3_v_5_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149901_2_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.5003
BRD-K79635719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17099
CENPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20034
BRD-K03301842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40966
GSE193402_0_v_2_imatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_BMS-911543_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0184293
PMC9510835-Table_2.docx-1-ZBTB34_ZBTB34	Rummagene Transcription Factor Associations 2026	1.0	null
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4188
GSE158834_7_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC2883591-pgen.1000979.s003.xls-NRSF_GENELISTS_WitOut_GeneSig_g-Supplemental_Table_3_REST	Rummagene Transcription Factor Associations 2026	1.0	null
ALG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52304
GSE153189_1_v_0_stat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pharyngobranchial	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.529
BRD-K19320442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09421
BRD-A84816049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66045
BRD-A99344113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06811
CRCGN015_MCF10A_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.36792
6934_PTPRC_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.560605
CTNNBIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70698
GSE210101,GSE210114_5_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
UNC93B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06143
BRD-K89110518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85861
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.56
Vascular smooth muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.078
GSE118939_1_v_0_nras_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE48812_7_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
Tibial cartilage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.132
BRD-K14166654	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46639
PMC8040704-jcav12p2673s2.xlsx-Down-regulated_genes_in_EBF1-Unnamed_5_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE180321_0_v_1_imperatorin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Matrilin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.292
GSE149621_3_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE189941_1_v_2_kdm4c_human	RummaGEO Gene Perturbation Signatures	1.0	null
SPDEF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01906
GSE200352_11_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K46951445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25786
BRD-K58469385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59522
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1188
PMC10181932-41588_2023_1366_MOESM4_ESM.xlsx-Supplementary_Table_2-Supplementary_Table_2_Additional_information_for_all_SOX9-dependent_genes_SOX9	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K63730594	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5609
BRD-K99034771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26919
Gingival fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.319
GSE214382,GSE214383_4_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10794847-mmc5.xlsx-PIAS1_KD_up-Table_S4_Differentially_expressed_genes_with_PIAS1_knockdown_in_the_progenitors_state_Related_to_Figure_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Brain - Anterior cingulate cortex (BA24)	GTEx Tissue Gene Expression Profiles 2023	1.0	2.13758
GSE201239_6_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hamstring muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.117
GSE243879_1_v_0_elapor1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
547_ARRB2_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.22273
BRD-K59919062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53116
ZNF577	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10365
GSE68925_1_v_0_fasudil_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE195559_6_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4584
GSE172189_0_v_1_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Carpel	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.481
Hippocampal mossy fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.706
GSE158431_2_v_0_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE223540_1_v_3_anxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.85204
BRD-K52436508	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46886
GSE181003_3_v_2_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
Muscular system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K42529194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02121
BRD-K27050140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68985
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ETS1_ETS1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K62718031	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02314
GSE214823,GSE214824_6_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K79697020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57556
organophosphate metabolic process	GO Biological Process Annotations 2025	1.0	null
BRD-K63119190	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26994
BRD-K27914478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06145
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.5347
BRD-K04443775	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1033
Esophagus - Mucosa	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.728509
CRCGN008_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.64007
GSE158834_11_v_3_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE48812_2_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE193993_4_v_2_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE131649_6_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K36726853	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0789
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4042
BRD-K76337122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69521
PSMD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4534
KLF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.853
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.0112
BRD-K22449045	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52299
BRD-K59772014	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.65825
BRD-K11942486	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33748
BRD-K94480039	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1098
GSE192513,GSE192515_2_v_0_atg16l1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8446
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_24hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ATP5F1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46715
GSE209598_0_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100369_PCx_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.44718
PMC8787225-Data_Sheet_1.xlsx-STable_2_DEG-Supplementary_Table_2_1150_up-_and_down-regulated_differential_expressed_genes_upon_GATA2_activation_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6048
CRCGN008_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.13393
GLIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.9644
BRD-K75529374	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06341
GSE238018_3_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE235066_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
TSSK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98452
BRD-K99944747	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54157
GSE184399_0_v_2_cnot1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148066,GSE157787_8_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Rheumatoid arthritis disease specific fibroblast-like synoviocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.677
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.2426
5738_NOL9_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.546792
GSE224311_3_v_1_chaetocin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K01100412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1025
GSE240386,GSE242143_1_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.3385
GSE228125_2_v_1_ptafr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE114013,GSE114014_0_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE224742_0_v_1_slc1a5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE242333_0_v_2_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Alx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.0504
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9954
Mesenchymal stromal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.462
BRD-K01705159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10349
GSE149903_4_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KMT5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.68155
ZSCAN29	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.1611
GSE201309_4_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Limb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.601
GSE129244_3_v_5_lmo2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prdm15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.2454
BRD-K47417426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10612
GNL3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60619
9443_TWISTNB_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.60901
GSE121866_1_v_3_six4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
lipid metabolic process	GO Biological Process Annotations 2025	1.0	null
GSE165678_0_v_5_stat5a_human	RummaGEO Gene Perturbation Signatures	1.0	null
PRR14L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02094
Interstitial matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.175
CRCGN016_MCF10A.WT.HP_24H:E20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.58772
BRD-K89141455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.11542
BRD-K28093873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25448
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.0439
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Combined-MYB_Combined_sgRNA_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE235587_2_v_1_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	1.0	null
TDRD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14791
GSE203308_14_v_0_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K81949875	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.60568
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-1_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
Navicular bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.564
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3929
TP73	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2995
Avian pallium	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Semitendinosus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.805
Cuboid bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.526
GSE235701,GSE261434_0_v_1_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9578
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.8589
GSE153189_2_v_0_stat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Oxoglutarate dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.621
GSE145915_0_v_1_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Preosteoclast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.779
OPTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50089
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3614
BRD-K63102090	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13149
GSE137325_3_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ACER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26869
PCF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51692
BRD-K83238251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27523
VEZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26462
PMC11615365-41467_2024_54246_MOESM6_ESM.xlsx-KK47-Numb-KD_vs_Ctr-KD-ensemblGeneId_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE110268_2_v_3_foxd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.4435
GSE147876,GSE147877_4_v_8_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4595011-pgen.1005555.s001.xlsx-BPTF_UP-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE57871_11_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC4407272-elife06857s002.xlsx-501M_BRG1-MITF_ComUP-List-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-2_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE69244_1_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K06816455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23814
GSE81803,GSE81912_3_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE235587_2_v_0_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_CUDC-101_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0106253
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1985
GSE126345_0_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8405683-41419_2021_4120_MOESM2_ESM.xlsx-Sheet1-Table_S2_MYCN-responsive_gene_list_1_5_fold_p_0_05_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K34095226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50393
NEDD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36116
GSE95077_1_v_2_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE203181_0_v_1_phosphoramidon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ventral aorta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.631
GSE258991_5_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE211262,GSE211263_0_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Periodontal ligament	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.1
GSE160817_5_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233679_6_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN010_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.41256
Photophore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.597
CRCGN015_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.37502
GSE191015_1_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE110268_1_v_3_foxd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.143
CRCGN015_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.21328
GSE148200_0_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE127790_10_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SMAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0892
GSE166294_0_v_1_etv5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_2_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K75506133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1151
GSE113817_2_v_1_bach1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K70305913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14652
Plasma membrane-derived chromatophore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.74
GSE98831_1_v_0_brca1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE183041_1_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9463
GSE140200_1_v_0_trim59_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE207471_2_v_3_btla_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.61522
Osteogenic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.78
Craniofacial region	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.0
PMC12224929-ADVS-12-2416784-s006.xlsx-DEG_circGLIS3_KD-Unnamed_6_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K02565327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56404
CRCGN014_HEPG2_24H:L05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.45078
GSE118548_1_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE94849_6_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_2_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE154337_0_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K80424876	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60535
BRD-K10269761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.08013
GSE197571_2_v_1_foxm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE96649_1_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.80163
Mandible	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.793
Thigh muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.277
BRD-K09271653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16299
GSE96641_3_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Integrin alpha1-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.557
OLIG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1314
GSE135514_2_v_3_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE193351_4_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CPSF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1325
GSE229973_4_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Vertebrate muscular system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0257
Signal Transduction	Reactome Pathways 2024	1.0	null
BRD-K04365932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47369
BRD-K26127722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15871
CRCGN011_HEPG2_24H:K12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03282
GSE113385_0_v_1_six1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142210_2_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE239578_0_v_7_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE120413,GSE120447_0_v_5_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE203485_1_v_0_zdhhc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K96945247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69122
GSE144500_7_v_6_ventx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE125211_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE236280_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE225982_2_v_0_ezetimibe_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE219195_1_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
Class A/1 (Rhodopsin-like receptors)	Reactome Pathways 2024	1.0	null
GSE185519_6_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE216273,GSE216292_14_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Psoas	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.677
4939_MED17_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.596373
BRD-K08219814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.23409
BRD-K37770214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04044
Dendritic filopodium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.739
BRD-K21384875	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.22158
CDC123	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75528
GSE162892_3_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null