association	dataset	threshold value	standardized value
CRCGN015_MCF10A.TP53.M_24H:I05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.00938
GTEX-T6MN-0011-R9A-SM-32QOZ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.0245
GTEX-UTHO-0011-R2A-SM-3GIKC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63959
Primary hyperoxaluria type 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.437
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
AML193	DepMap CRISPR Gene Dependency	1.0	2.70569
ST6GALNAC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05547
outer CP in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02396
FHIP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29821
GTEX-XQ8I-0726-SM-4BOPU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898337
KIT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0217374
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.2719
GTEX-Q2AG-3026-SM-48U1L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
FSTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88938
Prostate adenocarcinoma_PRAD_TCGA-HC-7738-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060206
leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.305361
RINL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00275
NEUROD2-26341353-CORTEX-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-QMRM-0008-SM-447B1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
BRD-K19381111	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15845
UTP11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00540462
WDFY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36178
MVK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00592838
GTEX-N7MS-0011-R4a-SM-2HMKW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19239
CD83	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0081775
TRIM35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32561
BRD-K17649115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14027
TNPO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.71068
monocytes	GAD Gene-Disease Associations	1.0	null
HCC1162	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57714
GTEX-QEL4-0426-SM-3GACZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31325
GTEX-WCDI-0008-SM-47JYE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
BRD-K06729289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40788
HSD17B4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00614665
charcot-marie-tooth disease type 4	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.91267
organic cyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
LIVF001-018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.50897
Neurofibroma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.894
SPHK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77761
BRD-K07303702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60432
GTEX-XUJ4-1426-SM-4BONT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
BRD-K26241953_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BIRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73755
WDHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74242
Leading edge membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.289
TT2609C02	CCLE Cell Line Gene Expression Profiles	-1.0	-2.19727
BRD-K85887470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.33492
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB2-627E_12Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.25901
MLKL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00694002
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15549
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.904317
GSE256181_2_v_3_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
AFDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47013
CRCGN011_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3122
Floret	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.135
TIAM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00579579
cellular_component	GO Cellular Component Annotations 2015	1.0	null
hsa-miR-646	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
CALY	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0107617
GSE213588_8_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Demyelinating disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.345
GRHL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00943731
glia	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.229299
GTEX-RU72-0011-R5A-SM-2TF6U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930057
Inflammatory bowel disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.868
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.876554
PMC8881251-18_2022_4183_MOESM2_ESM.xlsx-ERM_vs_P1-DEGs_ERM_versus_P1_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
ALKBH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00212
RPL22L1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0062736
ZNF655	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68124
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.54494
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26317
NFYA	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE236502_1_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNUC5	DepMap CRISPR Gene Dependency	1.0	6.29964
LMSU	CCLE Cell Line Gene CNV Profiles	1.0	1.56739
GSE210682_2_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QVJO-0011-R9A-SM-2S1QH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00817
FAM174C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46042
496100579_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.57044
NYAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.54851
NDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47326
GTEX-R3RS-0008-SM-48FF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
blast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062791
ACVR1C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00940947
A-Netherlands-602-2009(H1N1)_7Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.57538
H3K9ac_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Carapace	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.579
GTEX-U412-0008-SM-4DXTE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
GIMAP8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00583219
INSIG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95879
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.7972
PMC4407272-elife06857s002.xlsx-Hermes_BRG1-MITF_ComDown-List-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7482-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2998	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.935482
MKN45	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58784
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.834274
BRD-K14618467_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.484766
UACC-257	GDSC Cell Line Gene Expression Profiles	1.0	1.46295
GTEX-S4P3-0926-SM-4AD54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
SK-MEL-24	GDSC Cell Line Gene Expression Profiles	1.0	1.50388
CRCGN008_HEPG2_24H:D02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0478
pseudomyxoma peritonei	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.798282
BRD-K64525051_-666_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Oral sucker	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.699
GTEX-WFJO-0008-SM-4LVN7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
ATP11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48661
ZNF334	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7893
BRD-K93836438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03532
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TMEM107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94288
XYLB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00695424
Charcot-Marie-Tooth disease type 1G	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.653
Familial combined hyperlipidaemia_lymphoblast_GSE1010	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.47611
ZNF250	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75837
TAF6L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00614415
VGF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00469065
RPS6KA3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00552583
GTEX-Q2AH-1826-SM-2S1Q2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
DPM3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00530438
KLHL34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94119
BV-173	COSMIC Cell Line Gene CNV Profiles	1.0	2.24845
fgc4	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.748
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.847589
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
ADAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95907
FGFR1OP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84381
BRD-K31936306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56279
PRDM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01378
myosin filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.175188
Vitellarium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.516
CRCGN015_HEPG2_48H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.4396
outer CP in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.835416
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K03837143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40522
PIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75782
BRD-K13849122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68469
PRKACB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00634349
GTEX-N7MS-0011-R8a-SM-2YUMK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50022
TRAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50551
myeloid progenitor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065035
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55393
neuromuscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.189551
supraoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.14337
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065722
ANLE-138B	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13144
LRP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0923
Epulis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.055
GTEX-WWYW-3126-SM-3NB39	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831291
PRKCZ	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00577917
CD177	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56563
BRD-K15259924	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11783
CRCGN014_HEPG2_24H:H02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.68571
PSORS1C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39091
CRLF2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00776255
OGFRL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61361
copi vesicle coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.308122
BRD-K87537204	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12428
FLCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52863
GTEX-OHPN-0011-R9A-SM-4DXUH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41904
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.84262
Adductor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.806
LRRC40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41701
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.49165
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.959371
peripheral nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.24431
GTEX-RTLS-0008-SM-48FET	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
Caudatenucleus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.936173
GGT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20646
SETD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34771
CDKL4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00578527
BRD-K03213425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83921
monocarboxylic acid transport	GO Biological Process Annotations 2023	1.0	null
Charcot-Marie-Tooth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.405
TRIM41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89181
BRD-K40116023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16758
KURAMOCHI	COSMIC Cell Line Gene CNV Profiles	1.0	2.24845
ERICH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91864
PHTF2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00749503
ZNF227	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20543
GTPBP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57506
Charcot-Marie-Tooth disease intermediate type	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.061
BRD-K51050934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15295
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.918728
H3K4me1_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K20373726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60036
Amygdala	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.442
GSE162892_4_v_5_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
CD300C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00542784
Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4U1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K49865102_PD-0325901_A375_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KRAS.KIDNEY_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
WM88	CCLE Cell Line Gene Expression Profiles	1.0	1.52393
GSTP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00396431
MED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45973
Systemic mycosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.328
Nerve ring	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.68
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.687
GTEX-R53T-0008-SM-48FEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
brain	GTEx Tissue Gene Expression Profiles	1.0	1.28728
cSARS Bat SRBD_60Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.58554
UQCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09754
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.918054
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.43921
CRCGN015_HEPG2_48H:M17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.69174
OlfactoryBulb	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.25585
Flight muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.976
TGFBR2_knockout_293_GSE46211	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.66821
limb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.294939
THTPA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0048902
LGI4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47105
PIGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78843
FAM131A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47949
HCC2814	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34299
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.71459
Rectum adenocarcinoma_READ_TCGA-AF-2692-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU466	CCLE Cell Line Gene Expression Profiles	1.0	3.4092
SK-N-BE(2)C cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.518
PMC4595011-pgen.1005555.s003.xlsx-MITF_DOWN-regulated-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
SP140L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93414
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-UTHO-0011-R1A-SM-3GIJO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12675
KLF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97958
BRD-K70163662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85744
BRMS1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71298
CRCGN016_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.76821
hsa-miR-4311	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LB-11A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NATD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78399
BRD-K12824862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04617
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1367
GSE214248_0_v_1_cxcl8_human	RummaGEO Gene Perturbation Signatures	1.0	null
Charcot-Marie-Tooth disease type 1B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.904
PRKAR1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00427707
BPNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27341
CRCGN011_HEPG2_24H:P01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0677
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SLC38A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96081
GSE249544,GSE249637_6_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-N7MS-0011-R7a-SM-2HMKN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16168
extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YN-11A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ROS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00532364
BRD-K21680192_mitoxantrone_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RDH11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00456149
ACSL4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00693855
rosiglitazone_mus musculus_gpl1261_gse11343	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
globus pallidus, internal segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.876948
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02031
HTRA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10193
PMC6987220-41467_2020_14312_MOESM5_ESM.xlsx-P53_Spheres-3_names_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
post-mRNA release spliceosomal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.058
TRAK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05318
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2456
GTEX-R55F-1526-SM-2TF4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.854867
BRD-K14203360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03491
CRCGN014_HEPG2_3H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06473
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.941491
L1236	DepMap CRISPR Gene Dependency	1.0	2.45763
Ileocecum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.697
Ankylosing Spondylitides_macrophage_GSE11886	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.68678
RPEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85989
organization	GeneRIF Biological Term Annotations	1.0	null
Charcot-Marie-Tooth disease type 1C	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.734
macrophage	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.251606
BRD-K52175660	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.42957
H2BC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38932
plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.208137
Lauryl Dimethylamine-N-Oxide	DrugBank Drug Targets	1.0	null
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.538
UNC13D	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00542734
PHF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26067
LRAT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00962086
GTEX-OHPN-0011-R5A-SM-2I5FF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06572
RNF43	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00627036
TMEM82	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00787301
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IF-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM245	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85766
WM1799	CCLE Cell Line Gene Expression Profiles	1.0	1.97151
Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Peripheral neuropathy	ClinVar Gene-Phenotype Associations 2025	1.0	null
GABRG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00682268
SEC11C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15685
SAP18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6787
GTEX-QMR6-0011-R1A-SM-32PKW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28969
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4836-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lipids	GeneRIF Biological Term Annotations	1.0	null
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ronidazole-3557	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Neurofilament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.232
MALME3M	CCLE Cell Line Gene Expression Profiles	1.0	2.23466
BRD-K13206026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43556
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9407
BRD-K15259298	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.11061
TMEM59L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54809
TMIGD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00848882
AU565	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.667233
BRD-K12089436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02744
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
TMEM68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64483
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
TAPBP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00623622
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17516
OCIMY7	DepMap CRISPR Gene Dependency	1.0	3.22361
TE-4	COSMIC Cell Line Gene CNV Profiles	1.0	2.24845
Midgut diverticulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.851
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38326
outer CP in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03175
GTEX-T5JC-0011-R2A-SM-32PLZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911327
BRD-K40645748_mefloquine_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NPIPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68293
GTEX-RU72-0011-R8A-SM-2TF61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21132
CCDC71	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00523364
TGIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28901
vascular bundle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.105325
GTEX-XUJ4-0008-SM-4BOQI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
HRH4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00669155
mp9	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.285
H1-0	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42474
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.553078
BRD-K19962165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26277
Muscle - Skeletal	GTEx Tissue Gene Expression Profiles 2023	1.0	4.00955
APELA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35762
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.677238
Cerebral degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
PMC4777381-pone.0150624.s006.xlsx-dif_exp_AD-ZBTB38_ZBTB38	Rummagene Transcription Factor Associations 2026	1.0	null
GCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84082
Kidney renal papillary cell carcinoma_KIRP_TCGA-4A-A93W-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LRBA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00947292
HOXD11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1244
GTEX-X4XX-0011-R5A-SM-46MWN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06605
GTEX-UJMC-0726-SM-3GADX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.878227
GTEX-XOTO-0011-R1B-SM-4B65C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832152
ZPBP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00605167
GTEX-XMD1-0011-R9A-SM-4AT49	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5328
Spinalcord	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.54903
BLOC1S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68749
alopecia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.180937
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044578
GTEX-RNOR-0011-R9A-SM-2TF52	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81887
PTP4A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00560665
Spleen	GTEx Tissue Gene Expression Profiles 2023	1.0	1.34049
PMC12717993-MEC-34-e17796-s002.xlsx-ST12_WGS_RFMix_genes_2_anc-Unnamed_14_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4719	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
HORMAD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00585323
BRD-K67137502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00619
NCI-H510A	COSMIC Cell Line Gene CNV Profiles	1.0	2.24845
RGS9BP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00860209
HCC827GR5	CCLE Cell Line Gene Expression Profiles	1.0	1.39146
ALPL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00514071
GTEX-Q2AH-1626-SM-3GAF8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.975446
YARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8258
Atypical neurofibroma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.208
WIPF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00738148
BRD-K83344091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75333
GTEX-QVUS-0008-SM-447AY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
CRCGN016_MCF10A.WT.HP_24H:E19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.50935
NEK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20933
TIA1_KO_GSE54418_263_mouse_spinal cord	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ADCK5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00570949
ETHE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27391
GTEX-X4XX-0626-SM-3NMC1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.94379
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.8261
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEP43	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00569276
calcium folinate-7401	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CD68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95111
encephalitozoonosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.49482
GTEX-XUZC-0926-SM-4BOQF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848305
BRD-K17136501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17255
GTEX-UTHO-0726-SM-3GAEN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.865395
GTEX-XUZC-2126-SM-4BRW8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
BRD-K20069402	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.67865
CRCGN017_MCF10A.WT.HP_24H:J19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.234
GTEX-NPJ7-0011-R9a-SM-2TC5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06276
HSD17B8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00669282
ITM2C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00549581
Pseudomyxoma peritonei	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.923
CDK20	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00657989
monocarboxylic acid transport	GO Biological Process Annotations 2025	1.0	null
TADA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69777
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.889426
GRIK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0053025
496100545_HIP_possible Alzheimer's disease_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.79632
Necrosis	CTD Gene-Disease Associations	1.0	1.19445
A-VN-1203-2004(H5N1)_Day7-10^2pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.21261
Neuron projection cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.762
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1049
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A465-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
coated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.113013
GTEX-S7PM-0011-R5A-SM-3NM8G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902441
SUP-B15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.62334
hsa-miR-1224-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.251476
GTEX-QVJO-0011-R1A-SM-2S1QI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975451
WDR87	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0055502
membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.051312
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.886651
extracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
SNU-407	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KISS1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06481
UNC13B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74371
EBNA2-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7330-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.825695
BC-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.24845
Perturb_6447_OE|KD_EGFR|TRIM24_SRP100743	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-PWO3-0011-R1A-SM-2I5EW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30993
GSR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00539952
TNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44576
TBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28329
GTEX-PWO3-0011-R5A-SM-2I5EZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24399
Dystroglycan complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.964
ALDH5A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13697
NKX2-8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79801
Charcot-Marie-Tooth disease type 4C	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.543
ESPNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42107
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.857062
GTEX-NPJ8-0011-R4a-SM-2HML3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886782
BRD-K06537903	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2678
GTEX-XXEK-0008-SM-4BRW7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
GTEX-XLM4-0011-R4B-SM-4AT5C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.912711
BRD-K28057105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40206
MGE-Lateral region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18318
IDO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0048122
HOXC12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7709
FOSL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00688461
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888498
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6525
BRD-K40745976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47888
vesicle	GO Cellular Component Annotations 2015	1.0	null
CRCGN010_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.29744
BRD-K81206010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05569
HT144	DepMap CRISPR Gene Dependency	1.0	2.05579
TACC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42344
binding	GO Molecular Function Annotations 2015	1.0	null
OVK18	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50808
STAT3	ENCODE Transcription Factor Targets	1.0	null
GTEX-RM2N-1926-SM-48FCU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858609
EBF1-22473956-LYMPHODE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-NEUN_UNIQUE_DYS_GENES-PAX6_TLE_vs_TL_log2FoldChange_1_padj_0_1_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
cytoplasmic membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.051777
BRD-K52842821	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00978
GTEX-S4UY-1626-SM-4AD55	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
C12orf4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54344
CEBPB-20513432-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NAA40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.71521
SOGA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66905
Schwann cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.193
GTEX-S7SE-0011-R1A-SM-2XCDE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01116
YME1L1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00520911
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
Arteriosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.012
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.1976
KCNH7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00661485
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.903477
CD99	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25459
VSTM2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00608473
Appendix carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.585
LIF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00914017
GTEX-UTHO-0011-R6A-SM-3GIJW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900918
CRCGN014_HEPG2_3H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.00965
extracellular organelle	GO Cellular Component Annotations 2015	1.0	null
WTX_OE_GDS4802_34_human_HEK293	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.59289
BEX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36886
GTEX-WOFM-1626-SM-3MJFX	GTEx Tissue Sample Gene Expression Profiles	1.0	2.64185
CYSLTR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00810504
GTEX-QDT8-0011-R6A-SM-32PKI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874176
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.8629
CYP1A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00920484
BRD-K91973560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30252
ZNF180	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87332
hydrogenbonding	GeneRIF Biological Term Annotations	1.0	null
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.905485
NCI-H1299	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K46155894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58364
CRCGN015_HEPG2_48H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.56018
EDIL3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00738795
SMAD4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.007802
15558013-FigureS1b	GeneSigDB Published Gene Signatures	1.0	null
BRD-K46428124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03489
TRIM56	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86008
hsa-miR-4477a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
KCNQ3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00727956
Myelin sheath	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.941
GTEX-RM2N-0126-SM-48FDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00326
germ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.127408
Ovarian cancer	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.822185
GSE193258,GSE193259_9_v_0_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
submucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.275094
SIX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35075
BRD-K16935435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14721
BRD-K56375979	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38494
NF2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00886704
hippocampus (hippocampal formation)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.907957
GTEX-U8T8-0426-SM-3DB8X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993158
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K39580048_arg-a1-2 BRD-K39580048_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ABCB9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00573979
ARL14EP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93577
TUBD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0113469
TRAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49006
GTEX-WYVS-2426-SM-3NMA9	GTEx Tissue Sample Gene Expression Profiles	1.0	2.10369
MYRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28008
ACTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59989
SLC7A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85958
GTEX-XUJ4-0326-SM-4BOP9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
NCIH1869	DepMap CRISPR Gene Dependency	1.0	2.61526
GTEX-R55C-1926-SM-2TF4K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988207
CYP11A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00796274
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.447
telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055102
MRPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40652
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.4486
c211	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.627
LMNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41803
ARHGEF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05506
PUS7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00847451
ZNF606	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19304
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.2888
digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.622639
HSP90B1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00561793
GTEX-NL4W-0011-R9a-SM-2I3G1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6856
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.547
GTEX-TKQ2-1726-SM-4DXUP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
GTEX-RNOR-0008-SM-48FEY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
Spinal nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.431
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_7day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.9242
ITPRIPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07869
Perturb_3419_KO_USP7_SRP330182	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
reticulotegmental nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.966395
Lipocalin/cytosolic fatty-acid binding domain	InterPro Predicted Protein Domain Annotations	1.0	null
spermatid	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.525166
GTEX-WHSE-0011-R6A-SM-3P5ZP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830109
PMC5472759-ncomms15770-s2.xlsx-KIRC_mean_chr8_GISTIC_CN_by_gen-Supplementary_Data_1_TCGA_KIRC_mean_CN_near_MYC_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
Extrinsic component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.853
IL1RL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0055674
RCOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73592
GTEX-R55E-0011-R9A-SM-2TC6C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15772
Sulfate adenylyltransferase complex (ATP)	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.805
Hypothalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.447
periaqueductal gray substance, ventral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.916501
mp6	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.804
alcohol binding	GO Molecular Function Annotations 2015	1.0	null
PRDM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00657988
GTEX-QCQG-2026-SM-2S1PH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21459
GSE249544,GSE249637_6_v_7_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K53619784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76838
hsa-miR-153	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
CRCGN008_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2508
GTEX-QVJO-0526-SM-447CE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
paraventricular nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.847355
GSE165334_2_v_0_dabrafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IM95	DepMap CRISPR Gene Dependency	1.0	2.57765
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32673
BRD-K72216066	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11732
ATG2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36048
PI4K2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82367
ACAD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03574
QSOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34031
disease	GWASdb SNP-Disease Associations	1.0	0.023581
GTEX-QDT8-0326-SM-32PL1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52596
GTEX-Q2AH-1226-SM-48TZL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847918
CRCGN015_HEPG2_48H:A07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.12594
ZNF551	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73601
BRD-K18984088	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18455
ULBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64885
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
CHP212	DepMap CRISPR Gene Dependency	1.0	2.66388
GFI1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92993
HTR4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00547244
BRD-K77697841	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10037
TNFRSF17	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00647729
SLC16A4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0056086
STK32C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00570626
NDUFB5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0058072
SLC5A8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0051591
SULT1B1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00685776
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.877041
Calycin	InterPro Predicted Protein Domain Annotations	1.0	null
GTEX-V955-2526-SM-4JBJG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948814
BICC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00678929
IRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32762
NCIH226	DepMap CRISPR Gene Dependency	1.0	2.96652
FPR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00606554
GTEX-RU72-1126-SM-2TF6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20648
INKA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0059918
BRD-K53700261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08815
Satellite glial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.679
BRD-K56309946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65914
GTEX-XYKS-0002-SM-4BRWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
R3HDM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0113023
bronchoalveolar system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062161
GTEX-WWYW-0011-R5A-SM-3NB3E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987655
PFKM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00432589
AK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00704004
M band	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.667
hsa-miR-382	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
KLRC4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00791259
BRD-K20745677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09207
R3HDM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46643
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5712-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTSZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68006
Benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.158
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.0806
BRD-A45889380_QUINACRINE HYDROCHLORIDE_EFO27_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-PVOW-0011-R1A-SM-32PL6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00251
MREG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00641851
mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066711
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.239
Myelin sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.425
Glucocorticoid receptor pathway	WikiPathways Pathways 2024	1.0	null
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31565
GTEX-XUZC-0008-SM-4BOQG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
BRD-K73051782	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20565
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-3973	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35841
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.3277
Cerebral white matter	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.316
HINFP	JASPAR Predicted Transcription Factor Targets	1.0	null
Scape	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.268
peripheral portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.991779
PDZD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19298
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2J7-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MN-0011-R4A-SM-32QPG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61139
Atherosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
TCF3-18347094-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K84271229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71357
BRD-K42804674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56563
Carbon phosphorus lyase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.622
GTEX-NL4W-0011-R8a-SM-2I3G4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36932
FKBP9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00688266
VKORC1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24792
TJP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02454
EIF4E2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98274
a band	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.213669
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872821
DUT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52515
GTEX-WHSE-0011-R5A-SM-3P5ZO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867306
MIA PACA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.918684
Hypomyelinating leukodystrophy 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
PTHrP_KD_GDS1664_438_human_MDA-MB-231	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.62067
BRD-K50234570_-666_PC3_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MRPL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56908
H3K27ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN014_HEPG2_3H:J02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30926
MPZL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.388
hsa-miR-3913-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
CRCGN013_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.10042
TMK1	DepMap CRISPR Gene Dependency	1.0	2.59613
TNFRSF13B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00584446
BRD-K92018859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23458
KCNU1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00564755
hsa-miR-548c-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.226173
MARS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00704154
TXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79591
BRD-K70578146_dactinomycin_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31279
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.839343
myelinating schwann cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.501574
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.39529
SNAPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43787
THAP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.6352
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06429
GTEX-R55E-0008-SM-48FCG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061569
KCNV2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00535161
SDHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12569
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZA-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SEMA4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29305
albendazole-3164	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-S7SF-2126-SM-3K2B2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.61271
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.1014
Neuromuscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.191
m band	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.288091
Prefrontal cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.296
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6516
DLST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75714
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.75663
semen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.151735
hsa-miR-495	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
seed	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058743
peripheral nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.05061
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.2915
FAM210A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48161
outer CP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09519
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YR-11A-13R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-S4Q7-1426-SM-3K2B9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932714
hsa-miR-590-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.499447
SKMEL31	CCLE Cell Line Gene Expression Profiles	1.0	1.67559
ALK_KD_GDS2724_105_human_DAOY medulloblastoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GI-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.64506
fungal infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.726524
PCYT1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25427
GALNT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01449
GTEX-QLQW-1426-SM-2S1QU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21452
alveolar wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.173719
TCF3-18347094-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
C18orf54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51912
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.91573
CRCGN010_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.23185
GTEX-WWYW-0011-R1A-SM-3TW8G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835401
PAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28707
LRRN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28007
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.904768
bf2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.714
GJC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3878
Weight Gain	CTD Gene-Disease Associations	1.0	1.03308
X, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02541
BRD-K13566078_HY-10518_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC10952034-mmc2.xlsx-Table_S1-Table_S1_Pooled_shRNA_screen_analysis_to_identify_genes_selectively_required_for_the_proliferation_of_MYC_overexpressing_cells_Related_to_Figure_1_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.931477
RASGRP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0060104
IPO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82304
TTA-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.528
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06085
glycine-tRNA ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.742
PIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75997
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.863572
496100542_PCx_no dementia_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.31934
fatty acid transport	GO Biological Process Annotations 2025	1.0	null
Amygdala	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.851831
H2BC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55219
rosiglitazone_mus musculus_gpl1261_control_gds4036	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-Q2AH-0008-SM-48U2J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
BRD-K24496482_SB590885_SKBR3_3_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PRPSAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29884
BRD-K87158974	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0383
BRD-K78098006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11023
CERS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49463
NRM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86407
RPS14_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
TREX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90668
PTX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62561
BRD-K44626845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.68237
golgi-associated vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.188905
ATOSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20235
FCER1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00714161
spinal trigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.870733
Prostate adenocarcinoma_PRAD_TCGA-EJ-7328-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EBNA2-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K04930806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4171
lateral reticular nucleus (principal part)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.81597
Minor Salivary Gland	GTEx Tissue Gene Expression Profiles 2023	1.0	2.77459
BBIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83871
cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.604862
Brain - Spinal cord (cervical c-1)	GTEx Tissue Gene Expression Profiles 2023	1.0	1.71065
PMC4875603__F6	PFOCR Pathway Figure Associations 2023	1.0	null
RELA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00332239
SKMEL24	CCLE Cell Line Gene Expression Profiles	1.0	1.55033
Pancreatic adenocarcinoma_PAAD_TCGA-XN-A8T5-01A-12R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CACNA1S	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00719423
meptazinol-4188	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DDIAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06449
PPP1CA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00462479
carbohydrate metabolism disease	GWASdb SNP-Disease Associations	1.0	0.227808
spinal column	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.505887
CASKIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29922
BRD-A00522887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2369
EFM192A	CCLE Cell Line Gene CNV Profiles	1.0	2.87541
erastin-6369	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Hereditary neuropathy with liability to pressure palsies	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.872
ZNRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50761
OXTR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00736023
Aorta smooth muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.545
GTEX-QVUS-0011-R1A-SM-3GAD2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56981
RAD23B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00451598
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.133
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00175
BRD-K02708799_GSK-1059615_HCC515_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4ND-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.208
CAOV3	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58188
SUPT20H	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00492322
BRD-K63119190	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11374
SAP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02174
HPS6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00702217
H3K27me3_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FBXL19	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00592853
GAST	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00600668
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.034
RNF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37225
small intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.111691
RELB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00819348
BRD-A25184723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18606
HPS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15396
hsa-miR-4760-5p	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.837619
GTEX-WZTO-0011-R1B-SM-3NMAR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02322
GNG4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0062476
BRD-K47349869	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.20104
GMFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02202
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.48375
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YE-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KCNMA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00510445
BRD-K80535598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08334
Sto	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.682
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.979808
GTEX-SNMC-0008-SM-4DM5A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.83384
trypanosomoid form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.117573
BRD-K19830171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46947
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2194
Kidney Chromophobe_KICH_TCGA-KN-8422-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DAZAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63255
TCFCP2L1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PLK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00561105
ENPP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00599898
blood cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.256234
Septate junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.236
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
SASH3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0064688
abnormal glucose homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.176002
GTEX-WZTO-1026-SM-3NM9P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84997
CDC42EP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28326
OVCAR8	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.84794
HCC1897	CCLE Cell Line Gene Expression Profiles	-1.0	-2.65326
dicoumarol-2561	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.877041
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7236-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K62256869	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9786
Myelin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.428
ACTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88016
full	GeneRIF Biological Term Annotations	1.0	null
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65395
RHOA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00428874
PDIA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52974
SOAT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00763239
hsa-miR-3928	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
VDAC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00747884
RNF186	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00647033
Stipe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.386
ADAMTS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02277
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04382
outer CP in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.53904
BRD-K42757676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45832
GTEX-R55D-0008-SM-48FEV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
GTEX-X261-0011-R10B-SM-4E3JT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03038
vesicle coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.119768
BRD-K60219430_-666_SW620_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TRAPPC3L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00540139
Leaf disc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.639
FOXD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0189
Peripheral nervous system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
AFF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51668
DHRS4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00485539
STAT3	JASPAR Predicted Transcription Factor Targets	1.0	null
PCDHB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17975
gracile nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.914383
GSE182921_0_v_1_slit2_human	RummaGEO Gene Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.911337
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954858
PSMB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62225
GTEX-XPVG-0626-SM-4B65B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885248
PDHX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02395
Acute Myeloid Leukemia_LAML_TCGA-AB-2818-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DHRS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02173
TBX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89185
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04203
outer CP in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.976
ZNF670	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47766
protophloem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.158371
ITCH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00771408
spinal nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.474646
Mesothelioma_MESO_TCGA-TS-A7P0-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
Charcot-Marie-Tooth disease type 2J	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.542
GTEX-REY6-1226-SM-48FDR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837229
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.87653
Bmi1_Deficiency_GDS4816_323_mouse_Primary lung cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
U-2-OS	GDSC Cell Line Gene Expression Profiles	-1.0	-2.5801
resolution	GeneRIF Biological Term Annotations	1.0	null
BRD-K07825644	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11945
ARID3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33191
KP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26441
Exoskeleton	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.617
OLFM4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00630124
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
NUDT22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58716
LAPTM4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40728
BRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08346
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.946227
RDM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59999
Anus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.814
ACE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18399
RIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18347
MSN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21758
CYRIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49589
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.242672
PROC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00503039
SMARCA4-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
pyrantel-5088	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-X638-0426-SM-47JY2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949145
BRD-K09594570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.3267
CD6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00744205
CHRM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00437403
myeloid leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.118662
DSCAM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00699728
PALM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32714
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.437
pontine raphe nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13951
MME	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75507
BRD-K94441949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.34141
Hypodermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.245
LSM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12476
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.986414
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MI-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE208634_1_v_0_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.918054
PHF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97368
HESX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3511
C3orf80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11113
CRCGN015_HEPG2_48H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.12775
rostral (anterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.935465
BRD-K52075040_-666_HCT116_6.0_h_44.4_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PACADD188	DepMap CRISPR Gene Dependency	1.0	3.22391
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.87358
Diencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.447
Apical junction complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.366
cc95	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.762
TM6SF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00649713
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.869831
SIRT4_KO_GDS4823_30_mouse_hepatocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8355
BRD-K72060858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39271
GTEX-N7MT-0726-SM-3TW8S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839269
GTEX-T2YK-0008-SM-4DM6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.912262
BRD-K02113016_olaparib_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.326432
Charcot-Marie-Tooth disease recessive intermediate C	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.138
Vermiform appendix	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.934
CREB3L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86677
Lek	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.536
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2547
UBXN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41911
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1049
central gray substance of midbrain, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09575
TOR3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45469
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K00218068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.23635
PARP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41533
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A5EP-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KCNJ13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00514016
AASDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95252
GTEX-PWO3-0011-R2A-SM-2S1OX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6979
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09449
SLC9A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23935
GTEX-POMQ-0008-SM-48TE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.881954
GTEX-P4QS-1726-SM-3NB1V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1139
PPIP5K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50307
DOCK10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00597691
GUCY2F	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00553073
ERVV-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59751
PHF5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60161
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
KCNQ2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00511729
hypocotyl	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061242
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.734622
MVK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62731
sterol binding	GO Molecular Function Annotations 2015	1.0	null
TIMMDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79672
CCNI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53154
BRD-K63165456_Norcyclobenzaprine_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC6718408-41467_2019_11884_MOESM6_ESM.xlsx-TAD_genes_ST-EPN-RELA-Unnamed_4_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
AMIGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08253
Leaf tip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.829
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.856761
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.324
BRD-A29082194_GITOXIGENIN_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K27113545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05637
III	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.90265
outer CP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.38446
ASPHD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00620794
Edema	CTD Gene-Disease Associations	1.0	1.0894
Spinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.005
Autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
H4C15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66766
CISD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92349
GCAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20759
Cingulate cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.119
CDK10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00717825
BRD-K44935022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85964
Prostate adenocarcinoma_PRAD_TCGA-HC-8265-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K61807670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73464
BCL6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92327
oculomotor nuclear complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.39187
CADOES1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.65969
MAML1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19806
HEC1A	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82459
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08454
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.36832
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SPP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00450226
GTEX-XQ8I-1126-SM-4BOO2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843158
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04382
CKMT1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00583737
Small Intestine - Terminal Ileum	GTEx Tissue Gene Expression Profiles 2023	1.0	1.39399
ZNF860	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55332
VPS37B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40876
FCGR1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00571088
Sensillum trichodeum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.416
INSYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50388
UNC5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83447
GTEX-QXCU-0008-SM-48FCH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
SG in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00554
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.480091
ETV7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7622
STXBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76304
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NC-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00904824
brain_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.8539
PLAGL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00903655
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.18747
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.233
thyroid_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
BRD-K83972459_JWE-035_HCC515_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AP5Z1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85994
MTMR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62397
UNKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38826
GTEX-SNMC-1626-SM-4DM52	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42071
P2RX4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00642925
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7072-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Excretory canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.965
IGSF5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00711102
fastigial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08311
LMCD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00579506
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.301758
hsa-miR-548ac	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
NBEAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3675
GTEX-QDVN-1626-SM-48TZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.867474
NUDT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68763
C1QA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00611626
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.39824
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.838705
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6933-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ENPP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69759
Neuroma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.182
SPINDOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78715
marrow cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065418
Hemidesmosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.892
cellular component organization	GO Biological Process Annotations 2015	1.0	null
GTEX-S341-1926-SM-3K2BA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79454
MMP23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66683
16397240-SuppTable5	GeneSigDB Published Gene Signatures	1.0	null
GTEX-RNOR-0011-R4A-SM-3GAD3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17759
tyloxapol-5672	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-141	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
nc95	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.003
ZDHHC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31269
LRGUK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0047674
GTEX-X4EP-0011-R2B-SM-3P625	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17203
Rectum adenocarcinoma_READ_TCGA-AG-3732-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU685	DepMap CRISPR Gene Dependency	1.0	2.44684
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0038
IFNA5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00777541
DPPA4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00689584
Renal epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.906
C1orf210	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45569
NADK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00529833
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H6-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDK4_knockdown_133_GSE31534	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.16919
GALNT10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00732803
GTEX-TML8-0326-SM-4GICN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01269
NEURL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93787
Leaf base	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.685
BAIAP2L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68041
decreased nerve conduction velocity	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-S4Z8-0126-SM-4GICC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.915684
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.735
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5549
GTEX-VJYA-1726-SM-3NMDQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30596
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4814-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IL1RN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00831785
TXNRD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0056035
kawain-7369	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Ventral nerve cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.946
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.91885
hsa-miR-3689f	TargetScan Predicted Conserved microRNA Targets	1.0	0.37496
BRD-K80761414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58572
MAP4K3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0307
KYAE1	DepMap CRISPR Gene Dependency	1.0	4.24119
surfaces	GeneRIF Biological Term Annotations	1.0	null
alveolus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.142188
CSNK2A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86025
OR2A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19321
CADM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00718402
BRD-K08489825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42668
SARS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0057168
IL10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00706614
VCX3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50396
GTEX-T2IS-0011-R6A-SM-32QP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00179
cerebral cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GTEX-U8XE-0005-SM-3DB8I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
Bacteriocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.558
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5470-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5612
ileocecum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.113924
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.050582
BRD-K21119095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41326
HNF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03253
PMC8567138-Table_2.xlsx-Sheet1-IGFBP5_AND_IGFBP7_NOT_IGFBP3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XBED-0003-SM-47JWP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
GTEX-TSE9-2626-SM-4DXV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.84591
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RM-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE139016_0_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
KP4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44319
localization	GO Biological Process Annotations 2015	1.0	null
brown adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.681471
GOLIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5978
MELTF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00658387
CYP11B1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00510063
Human Immunodeficiency Virus	DisGeNET Gene-Disease Associations	1.0	null
GTEX-WHSE-0011-R4A-SM-3P5ZN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25719
Foot muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.345
CRCGN014_HEPG2_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.68577
Appendix adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.608
Appendix disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.907
CRCGN015_MCF10A.TP53.M_24H:B22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.053
NCIH2052	CCLE Cell Line Gene CNV Profiles	1.0	1.51799
GOLGA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67032
Pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829545
hematopoietic stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063071
PPIP5K1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71387
BARHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90828
VSIG10L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00558485
HS939T	CCLE Cell Line Gene Expression Profiles	1.0	1.79973
GTEX-XMK1-2426-SM-4B66I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943059
CRCGN015_MCF10A.TP53.M_24H:F17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.7287
CALB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42463
BRD-K60595964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80641
GTEX-QVUS-0011-R10A-SM-3GIK3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14507
abnormal lipid homeostasis	MGI Mouse Phenotype Associations 2023	1.0	null
sebum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.92291
BRD-K90138084	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80518
GAMT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00675361
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
GYPB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00777726
PAX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54122
GTEX-S33H-0008-SM-4AD6C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
BRD-K37165790	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70584
FAIM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00657826
SULT2A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00472739
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.25416
BRD-K93945680	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33533
hsa-miR-3142	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
CRCGN016_MCF10A.TP53.M_24H:P21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.20643
NCIH1048	CCLE Cell Line Gene Expression Profiles	-1.0	-2.02859
A10 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.748
BRD-K41684304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16512
hsa-miR-26b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7091-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DRD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00759842
GTEX-XGQ4-2526-SM-4AT57	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09411
GTEX-XOTO-0011-R7B-SM-4B64R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854608
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5321
BRD-K28623804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.06899
molecular_function	GO Molecular Function Annotations 2015	1.0	null
SGPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21202
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.944921
SLITRK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87964
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25538
TDRD12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00703482
BRD-K55946794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19806
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
GTEX-W5WG-0008-SM-4KL25	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
GTEX-NL3H-0011-R5a-SM-2I3GB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861424
BRD-K61681480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13776
Brain Lower Grade Glioma_LGG_TCGA-HT-8563-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K37760996	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.43851
UACC893	DepMap CRISPR Gene Dependency	1.0	5.6003
OBSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40225
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22426
BRD-K21680192_mitoxantrone_HA1E_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ETS1-22383799-G1ME-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN011_HEPG2_24H:I08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0034
PCI30	DepMap CRISPR Gene Dependency	1.0	3.19512
AP5S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56059
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.37
Colitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.628
Caudate nucleus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.23
GTEX-WFG8-2526-SM-3GILR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76882
PRKG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00673637
BRD-K94303022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14011
acute disseminated encephalomyelitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.729762
Lateral loop	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.956
MOCS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43707
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.656
BRD-K82194980	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91096
GAK	GDSC Cell Line Gene Expression Profiles	1.0	1.59854
Abductor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.63
PMC6617737-13059_2019_1747_MOESM1_ESM.xlsx-Table_s9_OLIG2_DEG-Gene_OLIG2	Rummagene Transcription Factor Associations 2026	1.0	null
head and face region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.914353
GTEX-T6MN-0011-R2A-SM-32QOW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69207
LU99	CCLE Cell Line Gene CNV Profiles	1.0	1.63595
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.104
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.579669
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.840485
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
GSE152699,GSE152723_0_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NHE3_Deficiency_GDS3323_599_mouse_Colon	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
OPM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43297
STYK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0115243
USP27X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62236
GTEX-N7MS-0526-SM-4E3JP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20248
Perturb_12628_KD_CYGB_SRP388176	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.64199
SMCO4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00795481
BRD-K11927976_-666_ASC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DLD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00467233
placenta_3a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
BRD-K86155080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26056
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05592
REEP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88365
BRD-K38615358	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.04426
SRSF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06456
ULK4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00633062
a11	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.979
496100646_TCx_probable Alzheimer's disease_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.8827
NHP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00577194
MAOA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00616688
TMSB4X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83614
halcinonide-7379	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hematopoietic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.398735
TREX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00939175
GSE214382,GSE214383_1_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CCL4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00552236
MRPL20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8438
BRD-K85015012_-666_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XOTO-0011-R8A-SM-4B65J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900664
SPPL2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00710188
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.822
PTRH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19992
COLO679	CCLE Cell Line Gene Expression Profiles	1.0	1.49924
H2BC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95119
cytoskeletal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043772
CLEC10A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00866784
KAT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16125
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6YC-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-600	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
SMAD2/3-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
cytoplasmic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.051312
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.32
lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.599273
Crus I, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16557
CSDE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95695
BRD-K21565985_XYLAZINE_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC7941712-40478_2021_1135_MOESM12_ESM.xlsx-Table_S4D_DEG_ST-EPN-RELA-Unnamed_6_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
Panicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.776
lateral parabrachial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07402
KG-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.68547
GSE206984_1_v_0_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7965
PMC4595011-pgen.1005555.s003.xlsx-BPTF_DOWN-regulated-Gene_name_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
SLC29A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52274
levobunolol-4016	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K86293440	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11692
RNF220	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57733
brain_3b	HPA Tissue Sample Gene Expression Profiles	1.0	2.28855
Prostate adenocarcinoma_PRAD_TCGA-V1-A8MM-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.41298
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.238
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8269
Congenital generalized lipodystrophy type 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
cytoplasm	LOCATE Curated Protein Localization Annotations	1.0	null
BRD-K97764662_P2499_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-TML8-0008-SM-4DXUI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849258
CNN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95195
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.59192
CHUK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0076659
stele	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.11306
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	43.563
TOE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45118
Tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.126
GTEX-S95S-0826-SM-4B64N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837065
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.25
BRD-K89300187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1396
SERTAD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64899
LN18	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.44119
extracellular region part	GO Cellular Component Annotations 2015	1.0	null
SIRT4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00481196
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26205
Oligodendroglia	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.684
Ms	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.823
GTEX-X638-0008-SM-47JZ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70N-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cingulate gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.162912
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
ARL5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03287
ABCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65866
SMARCA4	ChEA Transcription Factor Targets	1.0	null
RSBN1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47025
HES1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00498909
BRD-K00816476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09528
GTEX-P44H-0526-SM-2XCF1	GTEx Tissue Sample Gene Expression Profiles	1.0	2.47196
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.0191
PTGIS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00672413
Brain Lower Grade Glioma_LGG_TCGA-HT-8106-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K13859368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89657
Cytosolic fatty-acid binding	InterPro Predicted Protein Domain Annotations	1.0	null
SLC5A4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00529254
RASGEF1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00722718
TRAPPC6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08408
estradiol_homo sapiens_gpl1225_gse1486	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-RU72-0011-R7A-SM-2TF5U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26672
JAK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00587731
Chromosome 8q21.11 deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
GTEX-S7SE-0011-R5A-SM-2XCDA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846517
CRCGN015_HEPG2_48H:I07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.97889
amygdaloid complex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06628
BRD-K81801123	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01394
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.563
orbital frontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.86563
BRD-K52310606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10184
BRD-K16190564	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70146
Brain Lower Grade Glioma_LGG_TCGA-HT-7601-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bone marrow cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.416957
JJN-3	COSMIC Cell Line Gene CNV Profiles	1.0	2.24845
early-onset vitamin B6-dependent epilepsy 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.456
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.05448
T2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.726
hsa-miR-4680-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1395	GDSC Cell Line Gene Expression Profiles	-1.0	-1.43357
BRD-K84271926	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56541
mc2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.062
ORC4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00384466
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0777
GTEX-U3ZM-1226-SM-3DB9G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.956562
PRDX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39791
B9D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27574
SSH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31017
ESRRB-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Sieve plate	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.533
SCN4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21655
GTEX-R55F-0011-R8A-SM-2TF4F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04729
TAP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00721303
GTEX-WFG8-0008-SM-4LVN6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
FGF21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25683
immune	GAD High Level Gene-Disease Associations	1.0	0.293278
Plasma membrane respirasome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.522
hsa-miR-4762-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Sciatic nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.843
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-X585-0426-SM-4E3JZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0922
sciatic nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.470763
PBXIP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00531715
GSE159893_2_v_0_genistein_human	RummaGEO Drug Perturbation Signatures	1.0	null
Magnetosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.503
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
BRD-K44833533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13673
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.700262
MEGF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71248
GTEX-PWO3-0011-R3A-SM-2I5EX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18788
GTEX-V955-0926-SM-4JBJ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
LGALS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00958823
ZNF345	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83371
bone marrow	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.490229
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67O-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.911248
GTEX-QV31-0008-SM-447AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.875186
nizatidine-3047	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN012_HEPG2_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2025
SH3YL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26355
IER3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24723
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
hsa-miR-4480	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
MYL9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00504416
BRD-K13044705	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2015
SLC38A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0060645
Sebum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.877
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.976698
Talipes	DisGeNET Gene-Disease Associations	1.0	null
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8565
GTEX-X261-0011-R5A-SM-3NMB4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954453
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.987295
substantia nigra, reticular part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.3808
RPL39L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7913
RASL10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67902
procambium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.11306
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
AADACL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0081548
BRD-K10027041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02884
PAFAH1B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82857
GTEX-OXRN-2426-SM-2I5EQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841482
ANXA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66846
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.7886
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.929847
phloem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.365633
GTEX-WL46-0626-SM-3LK7R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.973282
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.383
BRD-K91623615_ABT-751_RMUGS_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EBI3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00701792
Chronic polyneuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.173
SCAMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27164
Lung squamous cell carcinoma_LUSC_TCGA-77-7463-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K86845618	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16821
CNMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02791
ALCAM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00506062
PTHrP_KD_GDS1664_71_human_MDA-MB-231 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K90934902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66721
GTEX-WYBS-0326-SM-3NM8S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37353
GSE185744,GSE185747_2_v_3_sox9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QDT8-0011-R4A-SM-32PKM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.998873
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.705173
Lung adenocarcinoma_LUAD_TCGA-49-4490-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pineal gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.359
SGK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00437618
BRD-K61315077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.48384
hsa-miR-539	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
bounding membrane of organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.057618
CAPRIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.06399
CTBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33791
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04382
Cotyledon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.942
Epithalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.359
RASL11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86942
KLE	DepMap CRISPR Gene Dependency	1.0	3.7152
t-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.604502
bretylium tosilate-3057	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-U4B1-0008-SM-4DXUW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.834713
GPR17	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00589573
Catenin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.122
GPR18	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00505327
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.993866
ChaGo-K-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.741
ELOVL4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0056479
RAB38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8608
KLHDC7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63323
SLC25A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56868
TE4	CCLE Cell Line Gene CNV Profiles	1.0	1.69602
BRD-K71139459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27371
SFTPD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00989024
TBK1_knockdown_53_GSE17643	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.5906
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.826734
Acrosomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.783
SLC25A37	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0052385
CDKL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0057392
ovum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.75247
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0335
ZCRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03706
GTEX-QV31-0326-SM-447BM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842227
CRCGN014_HEPG2_3H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.14065
DL-thiorphan-6249	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RNASE2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00618199
outer CP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.999748
MYLIP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00979863
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A7VF-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVUS-0011-R6A-SM-3GACX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0091
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.01455
STIM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00774747
HAT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0033847
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4768
RAP1GAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76571
Hypothalamus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.872743
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04101
GTEX-WRHU-0626-SM-3MJFI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46482
FEZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14924
GTEX-XMD1-0011-R8A-SM-4AT48	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924742
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
FOXD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40629
GSE213588_8_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4467436-oncotarget-06-6267-s002.xlsx-140527_cd44Cutoff_txt-OLIG2-M_OLIG2	Rummagene Transcription Factor Associations 2026	1.0	null
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040852
COLO-800	GDSC Cell Line Gene Expression Profiles	1.0	1.5295
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E8-11A-12R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
stomach	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060253
Anterior horn	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.928
LITAF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00840268
EZH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00444456
BRD-K32066855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21413
NECTIN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00560765
BRD-K53612668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30317
GTEX-WFG8-0001-SM-4LVN8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
BRD-K38282015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40124
SK-MEL-3	GDSC Cell Line Gene Expression Profiles	1.0	1.79743
protozoan form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.220152
Encephalomyelitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.124
Extensor digitorum brevis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.874
LRP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44991
Gravid adult	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.079
ABTB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98082
HOXB9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5827
TAF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00465571
KLKB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21075
GTEX-QCQG-0126-SM-48U27	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
CHP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00449018
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5157
NDFIP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00552216
betaxolol-5669	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-T6MO-2026-SM-33HB4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03589
central gray substance of midbrain, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01173
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.075089
inferior olive, dorsal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17479
PAR polarity complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.875
CLUH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9172
outer CP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1829
RTL3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00737915
FGD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32226
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3921
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.5349
hsa-miR-4758-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Autoimmune disease of the nervous system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.339
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3718
GSE162892_4_v_0_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13781
sebaceous gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.185115
abnormality of carbohydrate metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.160004
FBXO38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57922
GTEX-S4Q7-0008-SM-3NM8A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.987038
Extrinsic component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.002
CRCGN015_MCF10A.TP53.M_24H:N08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25405
COA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0397
GTEX-WH7G-0002-SM-4LVN9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
TNFRSF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41798
ERBB3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00360528
SYT4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00608691
GTEX-WHSB-0326-SM-3LK6K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.886569
Brain Lower Grade Glioma_LGG_TCGA-HT-A74H-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abducens nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.60449
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4283
NCI-H1734	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19004
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20R-11A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IFNA21	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00480433
LYSMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50086
CHPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99921
DUSP7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00669152
Node of Ranvier	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.316
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.61
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Paraplegia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.479
GTEX-TMZS-0008-SM-47JWM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.869143
CRCGN013_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.7345
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.486904
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.697
CRCGN017_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2545
BRD-K40724407	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51534
exocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.075969
Blastomere	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.178
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.8521
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.53779
ABCB11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00728026
forelimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.36302
NECAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11286
Brain Lower Grade Glioma_LGG_TCGA-DU-5872-02A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A45889380_QUINACRINE HYDROCHLORIDE_HCC15_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
VMP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00922063
ISTMES2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.72389
SNU1105	DepMap CRISPR Gene Dependency	1.0	3.52429
PPTC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9477
GTEX-OIZI-0426-SM-2XCEF	GTEx Tissue Sample Gene Expression Profiles	1.0	2.38023
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.712139
GSE163214_1_v_0_jazf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FUNDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05659
ERBB4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00722441
HCC38	CCLE Cell Line Gene CNV Profiles	1.0	1.8726
Perturb_12629_KD_CYGB_SRP388176	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.19354
hsa-miR-3654	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
AMT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00617047
BRD-K77908580_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02408
LAMB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25125
HLFA	CCLE Cell Line Gene Expression Profiles	-1.0	-1.99544
OCI-AML5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TULP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17944
ERG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00741687
RBM38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.26942
CCL13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00713843
TBK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13388
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.916963
BRD-K00509183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52384
RASA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81222
Cerebral gyrus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.119
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04382
GTEX-QDVN-0826-SM-48TZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.966095
KIFBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42997
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32739
CHEK1_knockdown_136_GSE31534	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.11242
BRD-K31883758	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03638
CRCGN015_HEPG2_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.7309
ARPC5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00981
hypothalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GTEX-WEY5-0008-SM-4LMKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041691
C12orf43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4751
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_4day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.69165
GTEX-W5WG-2326-SM-3GIJH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60842
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JA-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
detailed	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-4777-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
BRD-K69543414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70925
SORL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5072
IFIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15877
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A4ZP-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.291
p2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.794
GTEX-X88G-0008-SM-47JWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.916655
leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062142
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.42539
MMP23B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0081615
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838721
pontine raphe nucleus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0863
PHACTR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00607297
SKMEL2	CCLE Cell Line Gene Expression Profiles	1.0	2.06607
GTEX-U3ZH-0626-SM-4DXT3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
TXNIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36776
CHMP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77188
BRD-K64665523	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08216
Neural stem cell_Undefined_Human	CellMarker Gene-Cell Type Associations	1.0	null
CRCGN016_MCF10A.WT.HP_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.76071
BRD-K15427120	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69075
BRD-K64728664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98334
BEX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06264
BTLA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00804915
Polyradiculoneuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.055
BRD-K06842972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30401
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GTEX-QDT8-0011-R5A-SM-32PKN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902645
rosiglitazone_mus musculus_gpl1261_diabetes_gds4036	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MEI1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00582572
AHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73785
Opportunistic mycosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.35
hsa-miR-1295	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
BRD-A96799240_GR-109_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Schmidt-Lanterman incisure	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.746
GTEX-OHPN-0011-R1A-SM-2I5GB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960491
HDAC11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00456001
spleen	GTEx Tissue Gene Expression Profiles	-1.0	-1.00998
OPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38166
CRCGN015_MCF10A.WT.HP_24H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.18905
Adrenocortical carcinoma_ACC_TCGA-P6-A5OG-01A-22R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K56188606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93719
Corpus callosum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.517
ADK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0050379
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
hsa-miR-215	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
inside	GeneRIF Biological Term Annotations	1.0	null
ileum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.258243
ZNF121	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55748
structure	GeneRIF Biological Term Annotations	1.0	null
Hair	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.304
SIRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92685
golgi apparatus part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.116106
PPP4R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80306
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23278
TWIST1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00754342
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.931477
NHS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00533135
PCMTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66235
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.41763
ADRA2C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00748524
CSF1R	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00566653
GTEX-WH7G-0008-SM-4LVNM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
PIK3C2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1175
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213588_10_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SOX2_Deficiency_GDS4853_319_human_AZ-521 gastric cancer (GC) cell line - 8 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K88934376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.79798
GTEX-N7MS-0011-R5a-SM-2HMK8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83151
BRD-K66985689	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07281
TREML4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00531093
SNU478	DepMap CRISPR Gene Dependency	1.0	2.28536
STRIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03989
HS578T	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.770013
JMJD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01342
KDM1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00518039
BRD-K97224540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02919
Oligodendrocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.687
BRD-A45889380_QUINACRINE HYDROCHLORIDE_HCT116_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PLPPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79447
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
GTEX-XUZC-2026-SM-4BRW9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.82493
496100343_TCx_possible Alzheimer's disease_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21592
GTEX-UPJH-0626-SM-4IHJN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19846
Thyroid follicular epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.547
BRD-K08799216_pelitinib_A375_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66308
Oligodendrocyte precursor cell_Brain_Human	CellMarker Gene-Cell Type Associations	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
Nerve cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.937
Onion Bulb Formation	DisGeNET Gene-Phenotype Associations	1.0	null
ARH77	DepMap CRISPR Gene Dependency	1.0	6.19626
GTF3C2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00368356
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.6423
pineal gland	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06777
MCF12A	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.674482
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FO-11A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_24H:I12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.7247
Eiii	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.603
HLTF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40956
SKBR3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51553
LIPC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00571604
spinal cord	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
FOS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00398121
Perturb_10356_KD_BRD4_SRP093774	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.926154
BRD-K29555132_ARACHIDONAMIDE_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
IGSF6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00592158
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935313
MOR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10895
biological_process	GO Biological Process Annotations 2015	1.0	null
GTEX-P44H-0008-SM-48TDW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.861219
PMC3420248-1471-2164-13-213-S5.xls-Lipid_Related-Additional_file_5_Common_DE_genes_related_to_lipid_metabolism_in_AA_and_BJY_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.055592
pi1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.5
LC1SQ	DepMap CRISPR Gene Dependency	1.0	3.44812
15902281-TableS1a	GeneSigDB Published Gene Signatures	1.0	null
KLC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16502
anion binding	GO Molecular Function Annotations 2015	1.0	null
Crohn's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.812
Eye_CT1_glial cell	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
SCG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09765
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A410-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC3610249-1471-2164-14-184-S4.xls-miR-331-3p_targets-NR2E3_NR2E3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U3ZG-0001-SM-47JYF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
DIS3L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22303
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4363
SH3BGRL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32959
GTEX-TKQ1-1426-SM-4GICK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.949069
PANC-08-13	COSMIC Cell Line Gene CNV Profiles	1.0	2.24845
Charcot-Marie-Tooth disease recessive intermediate A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.317
HCC2279	CCLE Cell Line Gene CNV Profiles	-1.0	-2.52466
GTEX-U3ZN-0008-SM-4DXTL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.864271
Ventral posterior nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.712
U2-type post-mRNA release spliceosomal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.282
PMC9396374-Table_4.XLSX-AR_related_target_genes-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9314667-Table_1.xlsx-Regulons-NFATC2_NFATC2	Rummagene Transcription Factor Associations 2026	1.0	null
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.24486
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.625
ELF5	ChEA Transcription Factor Targets	1.0	null
GTEX-O5YV-1826-SM-2YUNI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960892
BRD-K23793049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4431
EBPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14117
BRD-K50129495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28913
ACYP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09156
H1-8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71125
GTEX-XUW1-0826-SM-4BOP6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.985115
GSE256181_1_v_3_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Charcot-Marie-Tooth Disease	DisGeNET Gene-Disease Associations	1.0	null
TUBA4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4928
GTEX-QLQ7-0826-SM-447B3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
Spinal root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.428
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.539396
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
SIRT4_KO_GDS4823_22_mouse_Liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
BRD-K56857396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06057
Leaflet of membrane bilayer	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.611
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.892383
ADCY5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0074699
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.069
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15681
Claw	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.889
TAL1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
PC3	CCLE Cell Line Gene CNV Profiles	1.0	1.36294
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
GTEX-S341-1026-SM-4AD71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
GTEX-P4QR-0008-SM-48TE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.8694
GTEX-T6MN-0326-SM-32PMK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68784
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.975872
CRCGN014_HEPG2_3H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.13523
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.896121
BLTP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00737267
RAPH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0087016
Ileal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.524
PCTP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00570633
TNNC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0073658
Glucosidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.569
TMEM238	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85763
BPI	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00571249
Polyneuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.794
BRD-K19352500_PROCHLORPERAZINE EDISYLATE_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VE-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CACNA1G	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00820239
hsa-miR-1245b-5p	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
Brain Lower Grade Glioma_LGG_TCGA-HT-A618-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PKN3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00750542
Neuron projection membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.288
PMC3506908__F4	PFOCR Pathway Figure Associations 2024	1.0	null
RAB5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48927
SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.894142
Appendix cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.907
TRPC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00771556
TRPV2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00564346
SUP-B15	COSMIC Cell Line Gene CNV Profiles	1.0	2.24845
NCI-H1299	COSMIC Cell Line Gene CNV Profiles	1.0	2.24845
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26132
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EU-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Compound eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.857
ALG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97493
red nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.884156
BFTC909	CCLE Cell Line Gene CNV Profiles	1.0	1.48434
F11R	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00722606
STAT6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00677977
bind	GeneRIF Biological Term Annotations	1.0	null
GTEX-X5EB-0008-SM-46MU3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
PFSK1	DepMap CRISPR Gene Dependency	1.0	4.90554
GTEX-RU72-0011-R6A-SM-2TF71	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915341
G0S2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00739008
496100327_PCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.77543
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.051405
Johnston's organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.994
GTEX-RM2N-0326-SM-48FD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
lm1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.819
KYAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30474
Cerebellopontine angle tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.013
GTEX-T5JC-0011-R4A-SM-32PLT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18584
CRCGN014_HEPG2_3H:M21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4686
mp10	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.176
OR2L3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00557983
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18632
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
HCC2157	COSMIC Cell Line Gene CNV Profiles	1.0	2.24845
BRD-K20157822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21391
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.981565
GTEX-WY7C-2626-SM-3NB2P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.039
icSARA deltaORF6_7Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.14805
CLEC14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26651
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053451
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2326
BOK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95923
allows	GeneRIF Biological Term Annotations	1.0	null
SKMM2	CCLE Cell Line Gene CNV Profiles	1.0	1.8852
NFKB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00897599
C11orf96	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17346
Subthalamic nucleus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.064
PI4KA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26115
SLC39A13_Deficiency_GDS3485_570_mouse_Chondrocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BICD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95359
FLNC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71467
Chronic inflammatory demyelinating polyradiculoneuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.55
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24582
lateral habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.96139
myelin sheath	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.595593
Proboscis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.585
HERC5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00429386
Hereditary mixed polyposis syndrome 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.286
BRD-K77953978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26222
GSE213588_10_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
glial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.232881
FOXP2-21765815-NEURO2A-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MAPK15	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00781703
SREK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00932011
FUT3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00485912
midbrain reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.54743
BRD-K39224209	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14255
PMC11385078-jciinsight-9-172336-s272.xlsx-1DEseq2_Report_AA_BL_vs_EA_BL-Unnamed_1_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S32W-2526-SM-2XCB8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4879
KMRC3	DepMap CRISPR Gene Dependency	1.0	2.13537
TKFC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00731384
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.918684
SW948	DepMap CRISPR Gene Dependency	1.0	2.52294
Immune System Diseases	CTD Gene-Disease Associations	1.0	1.04647
GSE210682_0_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-POMQ-0526-SM-3GADD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876357
MCCC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00507425
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.165
TTYH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8048
SLC26A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00422368
Artery - Tibial	GTEx Tissue Gene Expression Profiles 2023	1.0	2.02816
BRD-K39271757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80677
NCI-H460	GDSC Cell Line Gene Expression Profiles	-1.0	-1.71384
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9943
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.351
fat_8a	HPA Tissue Sample Gene Expression Profiles	1.0	1.11864
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.936
E2F1-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
EGR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87676
SIRT4_KO_GSE56321_391_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Musculoskeletal system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
LAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77164
ALMS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00607585
MAG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00580396
BRD-K45859834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43166
19523942-Table1	GeneSigDB Published Gene Signatures	1.0	null
Membrane stack	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.668
BRD-K07276273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07086
GTEX-SJXC-0326-SM-2XCFI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15143
trophozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.183758
BAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05604
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04358
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3773
nucleus subceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.848841
ADD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.61691
monocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.075772
HMOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00427
limbic system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
ZSCAN31	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6189
hsa-miR-3652	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.50709
Compact myelin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.942
PMC6167382-41467_2018_6258_MOESM4_ESM.xlsx-TEAD-associated_GSC-Specific_UP-Nearest_Ensembl_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PWN1-1726-SM-2S1O9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87084
BRD-K31780647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22896
GTEX-QMR6-0008-SM-447AV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
PSG8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00807054
Receptacle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.657
PMC9396374-Table_4.XLSX-AR_related_genes_from_GeneCards-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CCNY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02165
HEG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90283
PRSS36	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00694654
BRD-K20501114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39419
BRD-K95499061	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2843
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.171
RBFOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79902
Olfactory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.858
hsa-miR-3692	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
B4GALNT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94054
12086872-Table12c	GeneSigDB Published Gene Signatures	1.0	null
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.359
KDM5C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0056868
Pleated septate junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.667
CRCGN015_HEPG2_48H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.77492
HS-578-T	COSMIC Cell Line Gene CNV Profiles	1.0	2.24845
BRD-K08109516_-666_SKB_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
renal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.206499
Neurilemoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.661
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.938944
GSE261563_3_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Nervous system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
G292CLONEA141B1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.97359
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053529
BRD-K72452130	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10921
TRIM28	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00415584
CRCGN017_MCF10A.WT.HP_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4069
P2RY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92601
GTEX-WEY5-2226-SM-3GILQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62998
PIP5K1C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00648861
GTEX-UJHI-0226-SM-4IHJL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.867463
GTEX-S95S-1526-SM-2XCDH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20126
internal	GeneRIF Biological Term Annotations	1.0	null
HOP-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.863572
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.4566
CRCGN013_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.32332
all	GWASdb SNP-Phenotype Associations	1.0	0.02801
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5983
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.979808
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32673
GNGT2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00496968
GTEX-XOTO-0011-R9A-SM-4GICI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19884
mp4	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.354
Axonal neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.489
C15orf61	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95299
GTEX-XYKS-2526-SM-4BOPX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832416
BICR10	DepMap CRISPR Gene Dependency	1.0	2.26605
WM983B	CCLE Cell Line Gene Expression Profiles	1.0	1.57864
GTEX-WVLH-0011-R5A-SM-3MJFW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854108
renal epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.730208
ELK4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00669933
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.0089
EPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94088
GTEX-Q2AG-0011-R7A-SM-2HMJP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884268
DDRGK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00612514
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05228
Mesothelioma_MESO_TCGA-TS-A7P6-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.8422
Molybdopterin cofactor (Moco) biosynthesis adenylyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.135
GTEX-WFG7-0008-SM-4LMKB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
MAP3K3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00829578
NLRP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13659
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.325
AQP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00730256
NPIPB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12422
Glume	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.824
MT-ND4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12654
Spikelet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.72
Brain Lower Grade Glioma_LGG_TCGA-DU-6405-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TPM4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0065278
BRD-K91885806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55441
Seta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.418
BRD-K62219570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24656
GTEX-S4Z8-0626-SM-4AD6J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.996192
PPP2R5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08814
H4C8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99858
SCH-772984	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1252
substantia nigra, pars reticulata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.857711
TRIM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82309
ACSBG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03525
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.9807
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44533
ZPBP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00762687
cytosol	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.550186
Fungal infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.307
BRD-K85162396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53854
SALE	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63607
SSTR5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00517078
BRD-K04548931_EPIRUBICIN HYDROCHLORIDE_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GPATCH2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13847
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RV-02A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OSMR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00513771
Whipple's Disease_macrophage_GSE16180	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.34605
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.97915
Brain Lower Grade Glioma_LGG_TCGA-S9-A6UA-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
ZNF430	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50475
CDH3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00442504
GSE162892_3_v_1_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2987-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HLCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92098
BRD-K43002773_GDC-0068_HA1E_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0849
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01308
BRD-K66296774_-666_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Melanoma	DisGeNET Gene-Disease Associations	1.0	null
DNASE1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56096
SPRTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15808
GYPE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00483192
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.640023
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.534
BRD-K13317726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94728
HNRNPCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63707
BRD-K48557872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03853
runx1_18671852_e8dot5_lof_mouse_gpl1261_gds1511	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.009768
LETMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93015
neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.36771
IL1R2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00535008
LCN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07215
CCAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66246
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.392
ISCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44585
GSE249544,GSE249637_6_v_2_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RUFY4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00432617
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.877041
KCNA5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00704212
Food vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.861
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.925349
GTEX-NPJ7-0008-SM-4E3JS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.908975
SCN3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00562819
abnormality of the endocrine system	GWASdb SNP-Phenotype Associations	1.0	0.066537
Bladder Urothelial Carcinoma_BLCA_TCGA-SY-A9G0-01A-12R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.6144
SK-MEL-5	GDSC Cell Line Gene Expression Profiles	1.0	1.86276
BRD-K34797601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09115
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.01
PCNX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41109
CD68	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00549297
GTEX-VJWN-0726-SM-3GIJ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
RNF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9765
Lung adenocarcinoma_LUAD_TCGA-55-A4DG-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PDGFD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00579446
PMC5409051__F5	PFOCR Pathway Figure Associations 2024	1.0	null
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.298
FNDC4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0055481
DDX19A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81524
UACC257	CCLE Cell Line Gene Expression Profiles	1.0	1.35459
IGF2BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12623
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.867511
BRD-K08725381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01931
Autoimmune peripheral neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.454
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7S9-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4595011-pgen.1005555.s003.xlsx-MITF_DOWN-regulated-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
NMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70284
DDX51	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00523494
GTEX-RWS6-0008-SM-47JYV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
UBXN2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03898
GTEX-PX3G-0008-SM-48U2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
GRAP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00765504
Sporoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.854
PTPRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8012
PNPLA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48006
GABRB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0078791
BRD-K76176797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39339
hsa-miR-4494	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
PMC5637904-PATH-243-193-s016.xlsx-human_up_in_fat_SOX11-Unnamed_7_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HW-7493-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN011_HEPG2_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1023
ASIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53069
cingulate cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.171821
GTEX-UJMC-0008-SM-4IHKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70Q-01A-13R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WVLH-0011-R8A-SM-3MJFC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896233
Autoimmune neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.525
PJVK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61496
ACTR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54897
BRD-K06489778	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47183
membrane-bounded vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
spinal cord disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.266913
BRD-K64640769	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.1989
SLC27A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00400125
BRD-K64469421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13364
CRCGN015_HEPG2_48H:H06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.20789
HOXD12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8494
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.995821
IER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59951
PMC9170821-JCMM-26-3183-s001.xlsx-Astro_DAPI_ERG_VaD_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
IL12B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00579474
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.155
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.610138
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0319
GRM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0052632
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RARG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.010709
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.825808
TMEM132A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0729
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02241
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.188274
Prostate adenocarcinoma_PRAD_TCGA-EJ-7783-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A19500257_geldanamycin_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
GSE208634_1_v_2_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRABP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65768
primary motor cortex (area M1, area 4)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.890412
BRD-K01100412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66556
NUP54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37704
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.63607
LPS510	DepMap CRISPR Gene Dependency	1.0	2.22371
EFM-192A	COSMIC Cell Line Gene CNV Profiles	1.0	2.24845
CAPN15	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0066976
496100657_FWM_probable Alzheimer's disease_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.50433
rostral division of OFCi (area 11)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33016
fallopiantube_8c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
BRD-K32943037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13425
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1146
PMC9314667-Table_1.xlsx-Regulons-SOX6_SOX6	Rummagene Transcription Factor Associations 2026	1.0	null
CMYC-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PCSK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37141
Parietal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.045
BRD-K01225799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42355
BRD-K67525206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2778
outer CP in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.901339
BRD-K05649647_-666_HT29_24.0_h_20.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
LXR-22158963-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840025
STAT5A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00622208
FAM131B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38967
encephalomyelitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.597181
Palpus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.753
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PIAS1_Depletion_GDS5076_12_human_MDA-MB 231 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-X3Y1-2426-SM-3P5Z7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42545
BRD-A79768653_sirolimus_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PLA2G2E	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0072871
BLOC1S2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3038
JHH7	DepMap CRISPR Gene Dependency	1.0	3.40447
CHRM5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0067936
FANCA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00799343
USP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89891
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.828052
cytoplasmic vesicle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.072528
famotidine-6665	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44622
SAPCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47001
ARAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68166
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H3-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perinuclear theca	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.5
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.1769
GTEX-U3ZH-1626-SM-3DB74	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12059
PCI6A	DepMap CRISPR Gene Dependency	1.0	5.15927
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7252-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PVOW-0626-SM-2XCF6	GTEx Tissue Sample Gene Expression Profiles	1.0	2.24812
PLTP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00542668
lymphnode_5b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A7CZ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVJO-0011-R4A-SM-2S1QL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897315
extracellular vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.057922
Adherens junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.631
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.47272
PRKG2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00506299
NCIH510	CCLE Cell Line Gene CNV Profiles	1.0	1.37701
HCV_8week+IFN-a_None_GSE37715	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.53648
HOXB4_induction_GDS3036_138_mouse_ES cell-derived embryoid bodies (EBs)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NKX2-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12046
GTEX-QVUS-0011-R4A-SM-3GAE7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987538
PNMA6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52106
BTNL10P	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00694317
GTEX-U3ZN-1026-SM-4DXTC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
placenta_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
ADH7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00451132
cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.09636
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
DOCK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00889486
LDHA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0036466
BRD-K33637419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75984
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3623
Mewo	GDSC Cell Line Gene Expression Profiles	1.0	1.83837
PSME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86704
NFKBIA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00566466
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.281776
NCIH3122	DepMap CRISPR Gene Dependency	1.0	2.03531
SYT12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97421
cell part	GO Cellular Component Annotations 2015	1.0	null
KANK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37854
Lung adenocarcinoma_LUAD_TCGA-NJ-A55A-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBQLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84458
MRPL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72006
IKZF1_01_138	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.01778
BRD-K85015012_NNC 05-2090 hydrochloride_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Polar tube	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.852
TXN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00465166
GTEX-R55E-0011-R5A-SM-2TC5N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909647
DMS-114	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RWS6-2426-SM-2XCB9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25343
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8694
NCIH2171	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39099
GTEX-UJMC-0426-SM-4IHJF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
BRD-K16485616_mocetinostat_HT29_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K91500340	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.63311
STK31	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0085887
FBXL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68605
PMC5637904-PATH-243-193-s016.xlsx-human_up_in_fat_SOX11-Unnamed_6_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN013_HEPG2_24H:B07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.77564
RDH13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00424228
CPE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00528385
fat pad	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.689226
KDM5B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00373586
CL14	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60311
WFS1_KO_GDS4526_111_mouse_brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
CRCGN013_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.16248
KDM3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00908152
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.243
TRIM21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9329
GTEX-WZTO-0011-R5B-SM-3NMC5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846128
Dorsum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.182
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.21731
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NCIH1355	DepMap CRISPR Gene Dependency	1.0	4.91204
PMC6070530-41398_2018_200_MOESM3_ESM.xlsx-regional_cluster_PFC-MSC-age-bin_8_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.109
BRD-K22674439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99131
ARHGAP9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00822156
BRD-K91820608	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96525
MEX3B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00961051
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040429
CRCGN015_HEPG2_48H:J17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.26248
GTEX-RUSQ-1826-SM-2TF6E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837834
PMC4875603__F6	PFOCR Pathway Figure Associations 2024	1.0	null
salsolidin-4810	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-QVUS-0011-R9A-SM-3GIJA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.14741
diencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
ALKBH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58052
HEKTE	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6211
Prostate adenocarcinoma_PRAD_TCGA-G9-6364-01A-21R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4QT-1726-SM-2S1NQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08401
GTEX-RM2N-0008-SM-48FF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
systemic mycosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.74436
polyneuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.164359
IRAG2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00461459
GTEX-NL3H-0011-R4a-SM-2I3GK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914878
ICAM5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00943833
NCI-H2803	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40691
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.588832
IL4I1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00637743
SCN2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00653292
monocarboxylic acid binding	GO Molecular Function Annotations 2015	1.0	null
Leech infestation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.691
BRD-K12866026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24446
GTEX-U3ZG-0326-SM-47JXN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839703
ZDHHC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68156
medial subdivision of area 10	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09845
AOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04487
abnormality of metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.042406
NAALADL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47151
Inner acrosomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.87
Lung adenocarcinoma_LUAD_TCGA-50-6597-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAPK1IP1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81758
mononuclear phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074752
EMP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00454409
BRD-K98437821	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1036
BRD-K44576681	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33306
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.09385
NCIH522	CCLE Cell Line Gene CNV Profiles	-1.0	-2.72191
ITGB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79068
CRCGN010_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.45347
RARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41922
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.99646
SKMEL2	BioGPS Cell Line Gene Expression Profiles	1.0	1.39208
NCIH1299	CCLE Cell Line Gene CNV Profiles	1.0	1.54073
BRD-A70931301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57612
WFS1_KO_GSE33372_395_mouse_hypothalamus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.662
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.946227
BRD-K30633507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72634
Prostate adenocarcinoma_PRAD_TCGA-CH-5763-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K65265098	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12303
MDAMB415	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42571
GTSF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0057468
voltage-gated sodium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.968
TSPAN14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51353
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB2-627E_24Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.64295
GSE169205_3_v_7_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MEF2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00602799
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	12.9207
GTEX-W5X1-0008-SM-4LMKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
GTEX-VJYA-0001-SM-3NMDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.938737
NCS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00936884
Subapical complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.214
SON_KD_GDS4448_35_human_HeLa	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.8024
H3K9ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TXK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41458
SELPLG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00712594
MC-1010	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PPP6R3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28427
TRA2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0034168
PRKACG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56549
hsa-miR-3159	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
IDNK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00588548
CACNA1H	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00737501
XPOT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86531
HCC1569	COSMIC Cell Line Gene Mutation Profiles	1.0	null
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
IPC298	CCLE Cell Line Gene Expression Profiles	1.0	1.88625
PMC4383005-ncomms7500-s3.xlsx-Supplementary_Table3-Supplementary_Data_2_HES5_vs_HES5-_expression_intensity_ratios_during_NSC_progression_HES5	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K68065987_MK-2206_PC3_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K61050695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22438
ABCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95509
STAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16331
CRCGN017_MCF10A.WT.HP_24H:I09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.04425
Osphradium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.771
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-upregulated_in_ATF4OE_txt-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
CYB561D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99363
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NS-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUM185PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.878442
AKR1C1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00523035
Charcot-Marie-Tooth disease type 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.365
SMTNL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00720419
pyrithyldione-2740	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC7857731-elife-63093-supp1.xlsx-DEG_MITF-X6vsEV-SkMEL28-Unnamed_1_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
CLK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92089
organelle	GO Cellular Component Annotations 2015	1.0	null
SVBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72303
OPM2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5315
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
HDAC9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0063476
WDR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12395
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05947
VNN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00956221
BRD-K16843478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50301
NAAA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45583
VANGL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00521102
FPR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0072314
ZNG1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33167
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5014
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A706-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A57E-11A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A5ST-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZN-0726-SM-4DXT5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
LAMB3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00616561
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MIXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31527
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20N-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.82216
dorsolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.921743
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5010-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKMEL3	CCLE Cell Line Gene Expression Profiles	1.0	1.64091
CCDC160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30343
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.944921
hsa-miR-4430	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
dorsolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.13567
RHO	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00539261
GTEX-R55E-0011-R1A-SM-2TC6N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943506
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071222
BRD-K22668106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82144
SPACA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04052
GTEX-XYKS-0008-SM-4BRW6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
GTEX-XQ8I-1326-SM-4BOPV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843155
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.547
PNT-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.706
GSE240386,GSE242143_1_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE240386,GSE242143_1_v_4_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K57115335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06304
TMEM151B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61916
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	45.3886
HAMP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00524364
hsa-miR-4329	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
X	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.864417
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.034
CRCGN016_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.78116
hsa-miR-524-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052807
Schwann cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.154
ANKRD33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99739
sporozoan form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.119352
MEF2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3512
RSL1D1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00627901
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-E2A_Pre-Pro-B-Cells_ChIP-seq_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K90485414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03216
mononuclear cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067164
GTEX-RN64-0008-SM-48FEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
CRCGN017_MCF10A.WT.HP_24H:N21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0143
diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.249166
BRD-K73286847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64415
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T6MN-0011-R8A-SM-32QP3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2522
NTSR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00502739
SACM1L	Hub Proteins Protein-Protein Interactions	1.0	null
496100589_PCx_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.0314
GTF2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04013
Brain Lower Grade Glioma_LGG_TCGA-HT-7857-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAX5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00657717
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15681
BRD-K07409609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42652
CDK2_knockdown_132_GSE31534	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.01264
lymphoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.597666
Meconium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.845
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07957
hsa-miR-3675-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Olfactory lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.38
HCC1428	COSMIC Cell Line Gene CNV Profiles	1.0	2.24845
NAP1L4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00575526
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ASGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23004
GTEX-WWYW-0011-R6A-SM-3NB3G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871378
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.944921
GTEX-R55E-0011-R8A-SM-2TC66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10645
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9107
BCHE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0100242
SPOPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.49971
Taurine dioxygenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.796
DHX35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67497
vx2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.567
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15463
DNAAF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00620207
ARL6IP4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00855103
GTEX-SSA3-0008-SM-47JWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.052
MED21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80863
MRPL35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88123
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.16249
ZNF600	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50583
IRF2BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4221
GTEX-RVPV-0011-R3A-SM-2TF63	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824844
hair disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.125077
Prostate adenocarcinoma_PRAD_TCGA-HI-7169-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.824678
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.05563
GTEX-PWCY-0008-SM-48TE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830103
extracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19H-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
3-nitropropionic acid-6372	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RP-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.79482
CYB561D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1041
adrenal_4d	HPA Tissue Sample Gene Expression Profiles	1.0	0.932863
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.4211
lymphnode_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
NCI-H2228	GDSC Cell Line Gene Expression Profiles	-1.0	-1.61639
cholesterol binding	GO Molecular Function Annotations 2015	1.0	null
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.135
GTEX-NL4W-0011-R5a-SM-2I3GD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949937
copi-coated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.286614
SERPINE1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00711092
CRCGN015_MCF10A_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.73045
spinal cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.414673
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.0939
PMC3506908__F4	PFOCR Pathway Figure Associations 2023	1.0	null
BRD-M16762496_S1205_ASC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
icSARS CoV_12Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.92995
BHT-101	COSMIC Cell Line Gene CNV Profiles	1.0	2.24845
BRD-K51234905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39468
CSNK1G2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51519
BRD-K74317118	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35479
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35841
CH25H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24383
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.10128
STAU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86138
KE39	CCLE Cell Line Gene CNV Profiles	1.0	2.10271
GTEX-PWO3-0926-SM-2I5EY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33271
BACH1	ChEA Transcription Factor Targets	1.0	null
FAM120A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0513
LTA4H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0555
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.70515
KLHL5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00546843
BZW2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74832
PRM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00696827
RBM47	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00646312
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.37989
Autoimmune disease of peripheral nervous system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.343
PTDSS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86849
Brain Lower Grade Glioma_LGG_TCGA-CS-6188-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.657054
chr8_81434245_T_G_b38	GTEx eQTL 2025	1.0	1.14065
SKMEL5	BioGPS Cell Line Gene Expression Profiles	1.0	1.29024
FOXQ1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00500482
hsa-miR-570	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GTEX-QCQG-1326-SM-48U24	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K40862705	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53393
Cobalamin transport complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.631
neuritis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	2.26692
A-CA-04-2009(H1N1)_12Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	3.12547
OR2B6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85325
TGM2_KD_GSE23702_715_human_NB4 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
DMRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79667
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22778
BV173	CCLE Cell Line Gene CNV Profiles	1.0	1.76691
JEKO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7652
GTEX-S7SE-0011-R4A-SM-2XCDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07911
BRD-K82394273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62676
BRD-K73789395_ZM 336372_SNGM_6.0_h_102.71_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PAXX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36064
TRIM69	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00507424
GTEX-TMMY-0526-SM-33HBC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46985
Oligodendrocytic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.873
PUSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40921
gametocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.125415
seedling	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06046
RIEG2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00646826
SEMA3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00827965
Lysosomal storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.073
NCI-H1734	COSMIC Cell Line Gene CNV Profiles	1.0	2.24845
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2313
PDK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4033
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-0.847178
Charcot-Marie-Tooth disease type 1D	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.251
SCIMP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00495546
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.416
refined	GeneRIF Biological Term Annotations	1.0	null
CRCGN015_HEPG2_48H:L02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.95621
KYM1	CCLE Cell Line Gene Expression Profiles	1.0	2.65482
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55453
Cuticle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.237
WNK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0043362
Monocytes	dbGAP Gene-Trait Associations	1.0	0.101788
SAP30L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9444
TNFRSF10A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00526621
Dinoflagellate sulcus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.265
ZNF205	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08363
ES8	DepMap CRISPR Gene Dependency	1.0	3.50471
DGKK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00553965
FEN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00664673
GTEX-TSE9-0008-SM-4DXT8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.865032
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2025	1.0	null
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.5778
U138	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.3197
PRPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82946
USB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00570372
H4C13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79487
MFAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30664
CA14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99036
GTEX-PVOW-0008-SM-48TE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832041
Podocyte foot	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.905
FAM20B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84517
BT549	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.35476
FLT4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00659311
Steatotic liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.018
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.217139
hsa-miR-2355-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GTEX-QESD-1726-SM-2S1R7	GTEx Tissue Sample Gene Expression Profiles	1.0	2.90094
PKIA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00601989
C1orf21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66507
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.251606
midbrain reticular formation	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17381
GTEX-WFG7-0526-SM-3GIKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
TAOK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00547801
MYH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16761
GPR146	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00492999
Aorta cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.544
Adrenocortical carcinoma_ACC_TCGA-OR-A5L5-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TARM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0062236
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6059
GTEX-Q2AG-0011-R6A-SM-2HML7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850659
NFIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85895
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5985-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lung	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053107
BRD-A01346607_FLUMETHASONE_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RNASE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37727
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.938944
GTEX-RUSQ-0126-SM-47JWV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
JAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16874
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9977
CLMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28132
adipocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.702717
NCIH660	CCLE Cell Line Gene CNV Profiles	1.0	1.6238
CSNK1G1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00878645
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SNRK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00496662
IKZF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00575581
Neuritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.449
UACC62	BioGPS Cell Line Gene Expression Profiles	1.0	2.08831
BRD-K72717797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00143
ASH1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98871
GTEX-WVLH-0011-R7A-SM-3MJFB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17287
hsa-miR-4710	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
BRD-K55510118	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46983
GTEX-O5YT-0926-SM-48TDG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
Charcot-Marie-Tooth disease	ClinVar Gene-Phenotype Associations 2025	1.0	null
hsa-miR-1297	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
BRD-A02481876_Importazole_NCIH596_6.0_h_60.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MIEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6612
golgi membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.13635
ZNF561	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99818
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.839343
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.63304
FMR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2158
hsa-miR-3934	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
CDK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07411
TP53INP2_KO_GDS5053_544_mouse_skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
RARA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00539651
GTEX-R55E-0011-R6A-SM-2TC5T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925573
BHLHE22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37979
GTEX-XV7Q-0626-SM-4BRV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
TAF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59862
DFFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7804
ZNF780A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01381
GSE137702_2_v_1_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE213588_8_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EMD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00754615
USP13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52277
ion binding	GO Molecular Function Annotations 2015	1.0	null
TRIM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45218
GTEX-RU72-0011-R2A-SM-2TF6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09208
Perineurium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.654
SLC19A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00846191
GSE213588_8_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-PWN1-0008-SM-48TEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
VCPIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92985
Charcot-Marie-Tooth disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
GTEX-PVOW-0011-R5A-SM-32PL7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938624
CLIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96647
Hereditary sensory and autonomic neuropathy type 1A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.283
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5137
POMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42073
GTEX-PLZ4-0008-SM-48TE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.98979
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-RQ-A68N-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZYG11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48016
alpha-motoneuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.858
CIZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63529
hsa-miR-3185	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
BRD-K92167240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00936
BRD-K89932793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54819
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
CAMK1D	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00588927
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.839343
fatty acid transport	GO Biological Process Annotations 2023	1.0	null
BRD-K96382853	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07071
CCNE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56578
Mpk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.702
SEPTIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22873
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.125716
MRPS36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37929
HOXD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95467
DCUN1D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76639
CCDC28B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02859
BCL6-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.166
RHEBP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0047577
ZNF630	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67049
BRD-K56531121	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42201
PHETA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89823
GTEX-WH7G-2626-SM-3NMBE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22106
PCYOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.37162
0173570-0000-4715	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cytoplasmic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.083431
RSC1A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0060746
Female pudendum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.929
KLRB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00679269
Sarcoma_SARC_TCGA-QQ-A8VG-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9170821-JCMM-26-3183-s001.xlsx-Neu_DAPI_ERG_VaD_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
IFI6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00500382
TET2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00716903
TK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE213588_8_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.878859
BRD-K99210277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.31217
GTEX-UJHI-1726-SM-3DB9B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.902906
Arteriosclerotic cardiovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.7076
ATOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48649
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5689-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.984866
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE242199_9_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
SK-MES-1	GDSC Cell Line Gene Expression Profiles	1.0	1.51975
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
SNU626	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55697
KLK13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60687
Ensheathing glial cell_Olfactory neuroepithelium_Human	CellMarker Gene-Cell Type Associations	1.0	null
GTEX-XXEK-0126-SM-4BRVU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
GSE240386,GSE242143_8_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.873285
Charcot-Marie-Tooth disease type 4E	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.252
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23178
HCC2218	CCLE Cell Line Gene CNV Profiles	1.0	1.37297
vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.081943
FOXA1-21572438-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
sterol binding	GO Molecular Function Annotations 2023	1.0	null
H2AX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96163
GTEX-QV44-2226-SM-447A3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
MBD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00470798
PMC11285331-cd-23-0539_table_s1_suppst1.xlsx-Lost_AR_Peaks-Unnamed_20_AR	Rummagene Transcription Factor Associations 2026	1.0	null
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4282
ALOX5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00521218
Peripheral ganglion	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.166
GTEX-XLM4-0011-R8A-SM-4AT44	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892738
ARF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83908
A-CA-04-2009(H1N1)_18Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.29242
BRD-K03063480_PF-477736_HA1E_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
white adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.684735
Peripheral nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.158
GTEX-S7SE-0011-R2A-SM-2XCDC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83987
WDR76	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56202
outer CP in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.57661
vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
KPNB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00849873
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.42389
ring stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.254902
NCI-H2795	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.919749
BRD-K22316029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3779
GTEX-XMK1-0008-SM-4GICF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
KCNK9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00634195
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.7826
GTEX-SIU8-0008-SM-4BRUC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879661
SKMEL5	CCLE Cell Line Gene Expression Profiles	1.0	1.71342
PRODH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3307
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
GSE173282_1_v_0_marchf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF280A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5061
CRCGN017_MCF10A.WT.HP_24H:N22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0499
icSARA deltaORF6_12Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.834
Scutellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.393
hsa-miR-4796-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GTEX-NL3H-0011-R2a-SM-2I3GG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846392
hsa-miR-4745-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8615
doxorubicin_homo sapiens_gpl10558_gse42531	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN015_MCF10A_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.21441
PIAS1_KD_GSE44024_133_human_breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
skeletal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.370496
Gait, Drop Foot	DisGeNET Gene-Phenotype Associations	1.0	null
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.878859
SFTPC_KO_GSE35989_48_mouse_lung (type II cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
IgSF CAM signaling	KEGG Pathways 2026	1.0	null
Alx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.9785
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SN-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLXNA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00685042
ZSCAN20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65085
SK-MEL-2	GDSC Cell Line Gene Expression Profiles	1.0	2.00122
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A71V-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF207	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25239
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8163
H3C3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47332
SLC30A8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00679193
BRD-K29812154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01301
griseofulvin-4687	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TCF3	ChEA Transcription Factor Targets	1.0	null
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
HCC2157	CCLE Cell Line Gene CNV Profiles	1.0	1.50622
Hypodermal seam cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.193
GTEX-S3XE-1926-SM-3K2B3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43742
HARBI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55987
structural	GeneRIF Biological Term Annotations	1.0	null
GTEX-N7MT-0011-R8a-SM-2I5GU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14178
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0008-SM-4DM7H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
MYBL1_KO_GDS4485_350_mouse_Testis from 17 day old	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-XV7Q-0005-SM-4BRWI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
BRD-K18724553	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15524
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.665563
PLOD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00505164
CRCGN015_HEPG2_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.87356
BRD-K77947974_Fluspirilen_SKMEL28_6.0_h_4.21_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-N7MT-0011-R2a-SM-2I3GI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33794
Vaginitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.083
GSTO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87494
BRD-K80462316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96173
BRD-K11251396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33008
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
IQSEC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97522
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.676368
principal sensory nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10344
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.513
EDNRB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00771619
Retroviral intasome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.33
Spinal ganglion	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.166
BRD-K23075656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.35584
Junctional membrane complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.621
BRD-K16588281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10853
analyses	GeneRIF Biological Term Annotations	1.0	null
DMD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00673405
mp1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.203
Nymph	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.344
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.632
XYLT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18985
brain	HPA Tissue Gene Expression Profiles	1.0	2.24804
lower (caudal) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08432
CHL-1	GDSC Cell Line Gene Expression Profiles	1.0	1.85143
ASCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66053
external segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.82424
RCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87317
GM97	BioGPS Cell Line Gene Expression Profiles	1.0	0.856549
BRD-K83620635_MLS-0435534.0001_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KRT5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00552621
organic acid binding	GO Molecular Function Annotations 2015	1.0	null
BAK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00534031
BRD-K18077898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71538
GSE111061_1_v_0_tofacitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NHERF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2348
PLBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27447
BRD-K10812033	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3788
OCIMY5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.8614
PILRB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00588758
CRCGN017_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5721
CRCGN016_MCF10A.WT.HP_24H:P01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.31567
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6ZZ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.7316
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6055
Smooth septate junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.838
NEK11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00566463
colonrectum_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.08662
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.35158
monomeric	GeneRIF Biological Term Annotations	1.0	null
NDUFS4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00483709
outer CP in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.926125
TNNI3K	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00477245
GTEX-Q2AG-0011-R4A-SM-2HMKA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868509
CARM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00430591
BRD-K07079548_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NFATC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00749289
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.913181
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3689a-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.37496
SK-MEL-28	GDSC Cell Line Gene Expression Profiles	1.0	2.14568
Ileum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.675
LTBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38235
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.621831
FASTKD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00585589
EFS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72004
GTEX-QDVN-1226-SM-48TZ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
GSE137325_2_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WWYW-0011-R7A-SM-3NB3H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51369
pretectal region	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01662
ZNF573	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0048223
Calycin-like	InterPro Predicted Protein Domain Annotations	1.0	null
ANKRD33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60958
BRD-K90962922	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07441
CRCGN015_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.651
RNF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69054
RK-13 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.917
Brain Lower Grade Glioma_LGG_TCGA-CS-4944-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.945
hsa-miR-520d-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
FOXP2	ChEA Transcription Factor Targets	1.0	null
ZMYND19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99101
A band	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.689
SYNPO2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00573903
hsa-miR-571	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GPR179	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00530544
Kidney Chromophobe_KICH_TCGA-KN-8437-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5565-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-V9-A7HT-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC2A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97691
GTEX-R55G-0008-SM-48FEX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
hsa-miR-3929	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.882794
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.566
TMUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98075
GTEX-S341-1526-SM-4AD6K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
ACO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00725
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.87978
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947583
hsa-miR-1253	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GTEX-VUSG-0003-SM-3NMDK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926361
GTEX-TML8-1626-SM-32QOO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951715
GTEX-N7MT-0011-R4a-SM-2I3G9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945162
CEBPE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00606852
GTEX-WHSE-0011-R8A-SM-3P5Z1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934154
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7364-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WVLH-0011-R6A-SM-3MJFZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976985
GOLGA6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41229
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSB-2026-SM-3LK6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02232
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.885641
vestibular nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.915039
Tubercle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.898
PMC9170821-JCMM-26-3183-s001.xlsx-Oligo_DAPI_ERG_VaDadj_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1199
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7875
tiletamine-6516	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
GSE213588_8_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TMEM191B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16763
BRD-K44204252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20636
BRD-K22485581	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54269
C9orf40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15602
Husk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.529
Charcot-Marie-Tooth disease type 2B2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.144
PYDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26057
hsa-miR-26a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
WHAMM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77615
GTEX-Q734-1626-SM-48U1B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848541
glucose metabolism disease	GWASdb SNP-Disease Associations	1.0	0.227808
male reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.264353
NT5C3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95497
mp3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.329
microsporidiosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.78534
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
TMEM97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.002
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
GSE200430_1_v_0_sema3d_human	RummaGEO Gene Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23403
SLC9A3_KO_GDS3323_495_mouse_colon	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
contractile fiber part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.110156
KCNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35208
496100315_TCx_no dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.64064
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
central gray of the pons, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.4546
IL17RB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00433055
H1-10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14438
Amyotrophic lateral sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.111
Charcot-Marie-Tooth disease X-linked dominant 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.695
BRD-K13390322_HY-50940_ASC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045182
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
MVD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40365
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.938943
BRD-K50216176	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3534
BRD-K65503129_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
IL23R	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00609682
myosin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.074108
BRD-K28924192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05967
hsa-miR-380	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Ocellus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.352
cyclic-nucleotide phosphodiesterase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.221
GTEX-WL46-0011-R9A-SM-3MJFP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36141
COPS9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8171
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.59358
GTEX-SIU8-0326-SM-2XCDR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0824
Ring stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.156
Axolemma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.305
IL5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00607279
WIPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54211
coated vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.119768
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.838039
Charcot-Marie-Tooth disease axonal type 2S	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.112
SEC23IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47641
PTOV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82067
Neurodegenerative disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
posteroventral (inferior) parietal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.858589
GTEX-S3XE-0526-SM-4AD4G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.909053
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.35061
BRD-K02625776	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05303
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2722
outer CP in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09915
PMC3721393-bjc2013326x2.xls-Neuroblastoma_SOX10_Gene_Sign-Gene_name_SOX10	Rummagene Transcription Factor Associations 2026	1.0	null
VPS36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14611
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H0-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Toe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.946
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.2123
BRD-K66287173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40601
CRCGN012_HEPG2_24H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2599
GTEX-NL4W-0011-R6a-SM-2I3GA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830917
CRCGN013_HEPG2_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.11839
PUF60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20379
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.862449
BRD-K83691318_1219-1259_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN015_HEPG2_48H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.73914
BRD-K16485616_mocetinostat_HA1E_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-4711-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
ZBTB37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04218
Egg coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.683
anterior cingulate cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.326798
Adrenocortical carcinoma_ACC_TCGA-OR-A5L3-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Peripheral nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.928
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35467
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.154
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.966859
ADH1C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.006458
FAM86B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43507
hsa-miR-448	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Thalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.224
SARS-BatSRBD_60Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.98129
BRD-K54272776	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65962
lipid transport	GO Biological Process Annotations 2025	1.0	null
RAD54L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58983
PPP4R3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00951469
CRCGN015_HEPG2_48H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.26364
NHEJ1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00682737
HNRNPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41982
SNCA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00766311
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.960915
GJA9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00510288
GTEX-WFG8-1326-SM-4LVN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
NCI-H661	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MMP13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00439876
peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.403438
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4823-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40296
SPOP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61849
CHRNA4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00677111
CCDC51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60792
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1HY-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LRRC25	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00782551
SH4	CCLE Cell Line Gene Expression Profiles	1.0	1.37255
membrane organization	GO Biological Process Annotations 2015	1.0	null
DOK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00448453
MAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8956
DHH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00539696
Charcot-Marie-Tooth disease type 4A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.891
GCFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86714
AVPR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00901541
CENPU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05935
GTEX-XLM4-0011-R2B-SM-4AT5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18621
GTEX-PWOO-0008-SM-48TDU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
Brain Lower Grade Glioma_LGG_TCGA-DB-5281-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055879
GTEX-SNOS-0008-SM-4DM6I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
CUX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13647
PMC4777381-pone.0150624.s007.xlsx-dif_exp_AD-ZBTB38_ZBTB38	Rummagene Transcription Factor Associations 2026	1.0	null
DRAM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63368
ChIP_TCF3_18347094	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
SBDS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00669704
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SM-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A96308662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25285
BRD-K35727000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55796
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5682-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZDHHC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6424
membrane	GeneRIF Biological Term Annotations	1.0	null
HOXD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12742
establishment of localization	GO Biological Process Annotations 2015	1.0	null
myeloid leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.445268
ARF1	Hub Proteins Protein-Protein Interactions	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055859
Rectum adenocarcinoma_READ_TCGA-AF-2691-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRN-0011-R10A-SM-2I5GC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876329
HCC827	CCLE Cell Line Gene CNV Profiles	1.0	2.19964
DRD4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00588445
BRD-A36151937_Genistin_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K96133500	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16186
GSE261563_6_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
C6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00541533
CRCGN008_HEPG2_24H:I02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0925
GTEX-PWO3-0011-R6A-SM-2I5F3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13941
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-i-Classification_of_camel_SON_basal_genes_-_other_targets_IUPHAR_SON	Rummagene Transcription Factor Associations 2026	1.0	null
type 2 diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.50144
GTEX-R55E-0011-R7A-SM-2TC5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978973
TBC1D4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0042548
D-542MG	GDSC Cell Line Gene Expression Profiles	-1.0	-1.65652
ZNF596	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36412
OOSP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00542781
BRD-K97128200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30414
Eyespot apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.899
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.8492
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10463
GTEX-OXRN-0126-SM-48TDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826935
brain_3c	HPA Tissue Sample Gene Expression Profiles	1.0	1.87486
cerebral hemisphere	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
NOP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82855
LIG3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00632686
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.646
Charcot-Marie-Tooth disease type 2I	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.613
glucose-1-phosphate adenylyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.63
RGS8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00467823
CD4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00518004
GTEX-P4PP-0008-SM-48TDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
OCILY18	DepMap CRISPR Gene Dependency	1.0	2.1329
Nerve trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.212
BRD-K51849151	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45229
Tinea barbae	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.119
PNLIP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00730428
ATAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38839
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00067
Charcot-Marie-Tooth disease type 4H	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.51
NR2C1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00772008
hsa-miR-376c	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
non-myelinating Schwann cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.292
C12orf57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66389
BRD-K31542390_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
olfactory bulb	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
SLC50A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00715478
CRCGN009_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.19918
ENTREP3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00628879
BRD-K13792178	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3067
BRD-K65888165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28374
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12925
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.870512
BRD-A45889380_QUINACRINE HYDROCHLORIDE_THP1_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RTN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35405
PSG9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00824123
PMC9170821-JCMM-26-3183-s001.xlsx-Oligo_DAPI_ERG_VaD_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11017
B2M	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00792797
thyroid_5b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
Dinaciclib_SK-MEL-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.027068
GTEX-R55C-0008-SM-48FCF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848844
KLF6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00626236
Charcot-Marie-Tooth disease dominant intermediate F	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.106
SKMEL28	CCLE Cell Line Gene Expression Profiles	1.0	2.14079
perinuclear region of cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.170371
Atherosclerosis	CTD Gene-Disease Associations	1.0	1.04239
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.82
ADPRS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20588
HCC1419	CCLE Cell Line Gene CNV Profiles	1.0	2.66889
MAGT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00500434
RBPJ	ChEA Transcription Factor Targets	1.0	null
SYNGR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00626365
BRD-A81795050_U 18666A_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PYGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15984
GTEX-PLZ6-0008-SM-48TD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
Occipital lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.193
dorsomedial hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.84327
NKX2-6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00538651
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WN-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VUSG-0008-SM-4KL24	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
copi-coated vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.308122
Autoimmune disease of gastrointestinal tract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.681
GTEX-T5JC-0011-R9A-SM-32PLV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90609
SLC35B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02703
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RJ-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN009_HEPG2_24H:C16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04368
red nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.939474
GTEX-S4Q7-0226-SM-4AD5O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.938943
stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.0653
ELMOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50092
GGA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55505
GTEX-QLQ7-0008-SM-447AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
secondary spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.188511
PJA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27199
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19004
GTEX-Q2AH-1926-SM-2S1PN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925664
NPHS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0081372
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08229
BARHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5654
BRD-K19009595	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00221
PMC9314667-Table_1.xlsx-Regulons-MITF_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K94191869	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24714
CRCGN011_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.12735
CHTF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47092
caudal division of IPC (area 39)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.983804
Prestwick-675-7381	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K63779242	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19391
pentolonium-7375	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Charcot-Marie-Tooth disease recessive intermediate D	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.082
SCYL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07263
BRD-K61599229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37734
GSE193258,GSE193259_5_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A09539288_HOMATROPINE BROMIDE_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.437
BRD-K03829970_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.885918
BRD-K64222382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3428
COV318	CCLE Cell Line Gene CNV Profiles	-1.0	-1.85527
MMP20	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00718517
RYR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41114
GTEX-XV7Q-0426-SM-4BRVN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
GTEX-OHPN-0011-R7A-SM-2I5FI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.979956
RAD23A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63294
GSE193258,GSE193259_5_v_4_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A02481876_Importazole_A375_24.0_h_60.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HDAC10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00513224
GTEX-QLQ7-1826-SM-2S1R5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38909
UBR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15938
lipid binding	GO Molecular Function Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-4938-01B-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Schwann cell microvillus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.782
PLSCR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00349846
COX5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47355
NCIH2882	DepMap CRISPR Gene Dependency	1.0	2.81891
GTEX-P44H-0011-R1A-SM-3NM8J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835466
TYMS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00427005
RPS20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51368
S-16 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.137
spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.177334
HOXA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83135
Prostate adenocarcinoma_PRAD_TCGA-VN-A88L-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebral gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.153853
GTEX-QESD-0008-SM-447B2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
vascular tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.099116
TRIM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03299
outer CP in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.46876
hsa-miR-489	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
SEMA4G	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00611996
pravastatin-lactone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38573
Spermatheca	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.448
PABPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93199
WTX_OE_GDS4802_325_human_HEK293 embryonic kidney cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
acute myeloid leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.530298
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-NFK9-0426-SM-2YUNK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36522
CS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0044694
Prostate adenocarcinoma_PRAD_TCGA-HI-7168-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE165334_3_v_1_dabrafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-75-7025-01A-12R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Limbic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.196
HDDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84623
PSRC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00630879
ABCB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90157
PYGO2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00693887
BRD-K71919612	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5978
cloperastine-2549	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CREB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51669
Elytron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.703
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.827445
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
hsa-miR-4448	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
CPT1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00434796
Charcot-Marie-Tooth disease type 1E	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.169
POU2AF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00606898
LCLC97TM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.72631
BRD-A06840811	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07222
SHCBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25889
Neuritis	DisGeNET Gene-Disease Associations	1.0	null
GTEX-WFON-1726-SM-4LVMQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
ARL4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56362
Perturb_6262_KD_NDP_SRP188348	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8835
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.57635
Myelin membrane	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.809
BRD-K73494324	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.437
RBM39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82096
PLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1474
WDR12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0108101
ZNF251	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48074
BRD-K44062658	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19071
BRD-K54362440	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26284
SOX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08429
ERMAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06739
mouth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06017
TRAPPC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45967
GTEX-QCQG-0008-SM-48U2G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876923
CRCGN008_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4351
Adrenocortical carcinoma_ACC_TCGA-OR-A5J8-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FXYD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68972
demyelinating polyneuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.459373
MAN1B1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00402341
SPIRE2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00714992
PMC11464544-41467_2024_52946_MOESM10_ESM.xlsx-p64-markers-Supplementary_Data_7_Marker_genes_for_schwann_cell_subclusters_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
TP53INP2_KO_GSE54917_384_mouse_Quadriceps muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HCC4006	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44533
CRCGN015_MCF10A.WT.HP_24H:C02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01247
IGSF9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00872258
SLC25A24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65729
GTEX-OXRK-0426-SM-3NB2E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838376
Bladder-pericyte cell	Tabula Sapiens Gene-Cell Associations	1.0	0.879685
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.877041
SLC7A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33131
GTEX-T2IS-1126-SM-4DM6Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13916
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A71S-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K44328896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31914
GTEX-Q2AG-0008-SM-48U2K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
cellular component organization or biogenesis	GO Biological Process Annotations 2015	1.0	null
DNASE1L3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00809199
GTEX-X88G-0004-SM-47JZ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.283191
MSTN_KO_GDS3637_439_mouse_muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:D18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.07697
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.34267
SIRT4_KO_GDS4823_505_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K66282601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.40955
Head capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.063
GSE236486_1_v_0_arnt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HUS1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90663
Skin mucus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.603
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.07076
TP53INP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4926
IV	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.926879
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058851
CRCGN016_MCF10A.WT.HP_24H:A18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0468
SLC26A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0076645
GSE193258,GSE193259_2_v_4_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100575_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.15249
Lung adenocarcinoma_LUAD_TCGA-44-6148-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-W5WG-1126-SM-4LMK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.676368
GTEX-UPK5-0008-SM-4IHJD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
GTEX-Q2AG-0011-R2A-SM-2HMIT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40126
wing	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.05721
BRD-K74302837	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.009
DENND4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07081
WM2664	CCLE Cell Line Gene Expression Profiles	1.0	1.43157
19605494-TableS2	GeneSigDB Published Gene Signatures	1.0	null
GTEX-OHPK-1726-SM-48TC4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62427
GTEX-X261-0011-R7A-SM-4E3JJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828775
Epineurium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.977
SPHK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99853
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35841
GTEX-Q2AG-0011-R8A-SM-2HMK5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997755
GTEX-RWS6-1926-SM-47JXY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.82607
Charcot-Marie-Tooth disease type 4F	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.743
Palmitic Acid	DrugBank Drug Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5583-01A-02R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_3H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.75358
GSE213588_9_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CIBAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49202
GJD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00447325
BRD-K50008138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62256
SS18L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59692
BRD-K82126187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26954
ZFX_KO_GDS2718_150_mouse_embryonic stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ASAP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00829135
WDR37	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00847839
GTEX-XUYS-0005-SM-47JZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
BRD-K39332692	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9674
GABRR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00446938
SPAG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46281
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3343
Guillain-Barre syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.08
BRD-K50931403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86214
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20W-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.0405
DorsalRootGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.26423
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.258917
hsa-miR-548aa	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
CYB5R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18763
LRP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00866039
ELF5-23300383-T47D-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SLC7A5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00385547
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
2-iminoacetate synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.917
H3K27me3_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K52898544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00678
MAP3K7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05967
PPP1R16B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00564595
GTEX-QVJO-0008-SM-447AU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
AKR1B10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00658314
GTEX-T5JW-0008-SM-4DM5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
Sperm head	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.92
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.5023
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44474
intermediate portion of DFC (area 9/46)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12687
Wing	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.242
COX7A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16021
SHTN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0063827
BRD-K49865102_PD-0325901_A375_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HIVEP3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00591237
steroid binding	GO Molecular Function Annotations 2015	1.0	null
DNMT3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80589
ultrahigh	GeneRIF Biological Term Annotations	1.0	null
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.878859
Jejunal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.707
sterol binding	GO Molecular Function Annotations 2025	1.0	null
AMER1_OE_GDS4802_549_human_HEK293	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
plant form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057732
CLDN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27842
INMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27823
PITPNC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.887
CCDC9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95649
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
Internode region of axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.721
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.077
ACTL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49671
appendix cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.766759
External female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.925
Mandible	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.986
ZNF75D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74617
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC7064149-CAM4-9-2062-s004.xlsx-Table_S5-Table_S5_DEGs_between_low-_and_high-FOXP4-AS1_expression_groups_in_PDAC_tumor_tissues_FOXP4	Rummagene Transcription Factor Associations 2026	1.0	null
gallbladder_5b	HPA Tissue Sample Gene Expression Profiles	1.0	0.825422
GTEX-RTLS-0326-SM-2TF6A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955
Sarcoma_SARC_TCGA-SI-A71P-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X638-0326-SM-47JY1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
UBL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48348
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45R-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXC10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1732
TWNK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40519
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.994015
Charcot-Marie-Tooth disease axonal type 2T	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.246
Brain Lower Grade Glioma_LGG_TCGA-VM-A8C8-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.7787
carboxylic acid binding	GO Molecular Function Annotations 2015	1.0	null
USP28	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00600211
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.459145
GTEX-RU72-0011-R9A-SM-2TF67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33563
GTEX-S341-0008-SM-4AD6D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
CRCGN015_HEPG2_48H:B19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.61564
MIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6094
Mesaxon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.735
STK33	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.005846
MEWO	CCLE Cell Line Gene Expression Profiles	1.0	1.47556
AGTPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69208
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.31197
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.878859
tetroquinone-2999	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
forebrain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BRD-K72317601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23062
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4737-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HSP90AB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00438372
Charcot-Marie-Tooth disease type 2A1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.189
NKX6-3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40112
GTEX-OHPM-0008-SM-4E3IP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934654
COQ10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01904
PPIL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63774
MAP2K2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00588877
BRD-K48845054	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11062
fh15	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.07
BRD-K95763144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13138
BRD-K51572611	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.47575
496100564_TCx_no dementia_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.54704
gracile nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08101
Difficulty Walking	DisGeNET Gene-Phenotype Associations	1.0	null
TRIM17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18328
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.665
Motor peripheral neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.214
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04885
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28331
SARS-dORF6_96Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.79396
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7434-11A-01R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TESK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00706686
Avian pallium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.442
GTEX-T2IS-0011-R2A-SM-32QPF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21815
GTEX-N7MT-0011-R3a-SM-2I3GC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94988
PMC11285331-cd-23-0539_table_s1_suppst1.xlsx-Lost_AR_Peaks-Unnamed_19_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Spinal cord	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.133
ZNF764	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20168
JHOS4	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64851
Corpus striatum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.23
SGSM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59247
hsa-miR-3689b	TargetScan Predicted Conserved microRNA Targets	1.0	0.37496
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.294581
C bouton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.047
SMARCAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66854
SOX11-22085726-ESNS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.2
PMC13187244-41392_2026_2766_MOESM2_ESM.xlsx-Table_S17-Table_S17_Differentially_expressed_genes_in_OCI-AML3_cells_ZMIZ1_inhibitor_SIH-001_4E_vs_DMSO_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
PPFIA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42905
CI-1040	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13411
outer CP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.909904
ACMSD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0061584
GTEX-XOTO-0008-SM-4GICE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
GTEX-S4Z8-0226-SM-4AD5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873304
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02031
Hereditary Motor And Sensory Neuropathy	DisGeNET Gene-Disease Associations	1.0	null
DOCK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00639555
CEBPB	ENCODE Transcription Factor Targets	1.0	null
CRCGN016_MCF10A.WT.HP_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6982
rk-13 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.735971
CHMP2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00902793
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-PAX6_UNIQUE_DYS_GENES-PAX6_TLE_vs_TL_log2FoldChange_1_padj_0_1_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4421	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
CNGA3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00684766
promastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.244545
BRD-K11457257	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9305
cls1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.689
PHTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74737
LS411N	CCLE Cell Line Gene Expression Profiles	-1.0	-1.59394
PMC7439574-13148_2020_914_MOESM2_ESM.xlsx-log2_fold_change_-2-1280_genes_are_more_than_four-fold_downregulated_in_PRDM8-_-_compared_to_control_PRDM8	Rummagene Transcription Factor Associations 2026	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7897-01A-21R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.954085
METTL21EP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6985
TFDP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17772
GTEX-VUSH-0008-SM-47JWK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
BRD-K77445233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32809
HOXC9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9888
Schizophrenia	DisGeNET Gene-Disease Associations	1.0	null
PMC9013128-NIHMS1795992-supplement-4.xlsx-501mel_ARID2_KO_Downregulated-Gene__name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
protein binding	GO Molecular Function Annotations 2015	1.0	null
PLEKHG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45158
NECTIN4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00711577
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.978212
EMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87587
GTEX-OXRP-2526-SM-2S1NO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24221
SNU213	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82172
placenta	HPA Tissue Gene Expression Profiles	-1.0	-1.21673
HNRNPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33537
GTF2A1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25113
NRXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56113
DUSP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44206
acute myeloid leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.132252
TIPIN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00866908
ZZZ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78927
GTEX-QEL4-1226-SM-447A4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828037
BRD-K29802952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2782
adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.614974
Perinuclear region of cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.976
GTEX-Q2AH-0226-SM-48U1I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
NMCG1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.72619
jejunal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.30032
hsa-miR-328	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
NIBAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21541
GTEX-SUCS-1726-SM-32PM8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39362
HMCB	CCLE Cell Line Gene Expression Profiles	1.0	1.6088
TNFRSF12A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0047786
Charcot-Marie-Tooth disease axonal type 2F	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.374
UTP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96201
FOXP2-21765815-NEURO2A-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
RVH-421	GDSC Cell Line Gene Expression Profiles	1.0	1.98745
GTEX-QDVN-0008-SM-48U2D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
TSPAN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21391
URI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10488
UACC-62	GDSC Cell Line Gene Expression Profiles	1.0	2.82299
GSE213588_10_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MYORG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74921
ERFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41828
ITPR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00728451
Sieve tube	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.868
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3048
membrane-bounded vesicle	GO Cellular Component Annotations 2015	1.0	null
ZC3H12A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00570951
GTEX-QEG4-0008-SM-48TYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
network	GeneRIF Biological Term Annotations	1.0	null
fatty acid binding	GO Molecular Function Annotations 2015	1.0	null
hsa-miR-4465	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GANAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22685
ZNF688	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87239
cavity	GeneRIF Biological Term Annotations	1.0	null
Neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.296
POLR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14782
MPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72316
LRRC8C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0107329
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.121
PF-01378883-00-6368	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-NL4W-0011-R2a-SM-2I5GV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43971
hsa-miR-208b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Charcot-Marie-Tooth disease type 1F	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.834
BRD-K11242872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49254
GTEX-N7MS-0011-R2a-SM-2HML6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34799
NCI-H2023	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11027
CEMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6056
CRCGN016_MCF10A.WT.HP_24H:A21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.36515
DCTD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89637
GNA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7578
ALG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4666
GSE138863_2_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cell type benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.032
adult stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05865
CRCGN014_HEPG2_24H:J18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.464
CDC42BPG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00685018
WASHC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53296
NCI-H2170	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GABRE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02719
NCIH23	CCLE Cell Line Gene CNV Profiles	-1.0	-2.45962
GNG14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14554
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08709
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.346
APOBEC3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3924
SESTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80054
GTEX-UJHI-0008-SM-4IHL1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
PMC8454054-13059_2021_2489_MOESM17_ESM.txt--SOX10_SOX10	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K50000283_PHA-767491_HEPG2_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.219
PMC5740759-40246_2017_131_MOESM1_ESM.xlsx-Table_S6-Synteny-Syntenic_Analysis_for_29_HSF1-CanSig_8q_Genes_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H2110	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K22940496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.43336
NADK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0063506
JAK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05473
CAL120	DepMap CRISPR Gene Dependency	1.0	2.79764
CERS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17536
GJB3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00566982
DLG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00450425
496100653_PCx_probable Alzheimer's disease_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.59511
Astrocyte projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.844
GTEX-OXRO-0011-R9A-SM-3NB1X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01734
GTEX-OHPN-0011-R2A-SM-2I5FB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32435
BRD-K35638681_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
golgi-associated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.134669
BRD-K38854468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42553
BRD-K32782599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06368
FDX2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00580247
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5767
NME1-NME2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00347082
GSE87615_1_v_3_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ANXA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05329
perinuclear theca	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.585523
GTEX-QDT8-0008-SM-48U2F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
raphe magnus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39813
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16332
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.51292
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.21888
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.934585
schwann cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.241746
SUMO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00792896
GTEX-TSE9-0011-R9A-SM-3DB7Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06613
BRD-K77908580_entinostat_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.947953
GTEX-T6MN-0011-R1A-SM-32QOY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871397
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.009
GTEX-QV44-0008-SM-447AX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
hsa-miR-943	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.457
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.838705
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043476
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
GTEX-X585-0011-R4B-SM-46MVH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852584
Acute Myeloid Leukemia_LAML_TCGA-AB-2938-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09549
TBX4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0104988
Nitrate reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.548
BRD-K67535324	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10898
FCRLB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00611073
BRD-K39526528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16332
Aorta thoracica smooth muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.563
BRD-K67597437	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22304
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MX-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDAMB436	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32778
COLO680N	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56571
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.105
VKORC1L1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00693123
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8479
TRO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4896
Slow Progression	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K86002795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3585
BRD-K44684577	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27627
PMC3245917-supp_gkr685_nar-01129-x-2011-File015.xls-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Mitchell syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.226
SYNCRIP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0049238
Charcot-Marie-Tooth disease type 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.939
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30151
CYBA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64775
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.96253
Multiple sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.208
MRPL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26721
Edinger-Westphal nucleus (accessory oculomotor nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.934759
RAGE_knockout_269_GSE22873	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.7097
RNASE8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52407
BRD-K16915521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37775
Protocerebrum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.706
metaphloem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.166789
ANPEP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00616582
CD3G	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00628379
Oleic Acid	DrugBank Drug Targets	1.0	null
UXT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00659293
Cardiomyopathy_Myocardial tissue_GSE5406	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.50648
GTEX-REY6-0626-SM-2TF4G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890593
Cul7-RING ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.891
STARD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59099
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10463
able	GeneRIF Biological Term Annotations	1.0	null
GTEX-OHPN-2926-SM-3LK65	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14743
GTEX-XUJ4-0626-SM-4BOOO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
BRD-K75915595	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66837
Sensillum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.299
Cell surface furrow	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.723
GTEX-XUYS-0008-SM-47JYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
endometrium_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
SH3D19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69657
COLO800	CCLE Cell Line Gene Expression Profiles	1.0	1.411
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.863033
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
nucleus	GO Cellular Component Annotations 2025	1.0	null
primary auditory cortex (core)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.24661
BRD-K50985475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48541
Paranode region of axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.582
forestomach	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.146831
UACC257	BioGPS Cell Line Gene Expression Profiles	1.0	1.05931
LOXL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00441777
BRD-K10900122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.1392
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.581218
ZNF648	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90654
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874746
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35841
alveolar sac	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.125146
CD24	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00510583
GTEX-QMR6-0011-R7A-SM-32PKL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960834
GSE213588_8_v_7_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SLC39A14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64556
GTEX-TMMY-0008-SM-4DXU3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
CRCGN015_MCF10A_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.7304
extracellular vesicle	GO Cellular Component Annotations 2015	1.0	null
BRD-K24125966	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00423
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08469
BRD-K24081812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.08761
Apical cortex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.624
FDXACB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14479
halofantrine-6509	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
mepyramine-5869	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SC5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44441
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041124
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.0181
extracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K58772419_AZD-6482_HA1E_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TPRKB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0040762
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.79826
CRCGN015_MCF10A.TP53.M_24H:B20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.8253
PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5	Rummagene Transcription Factor Associations 2026	1.0	null
GSTA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00589999
BRD-K70643771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.43947
ZNF462	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65597
BRD-K13057245	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03219
Temporal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.204
BRD-K61278167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28027
A-Netherlands-602-2009(H1N1)_48Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.43968
BRD-K99660943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47538
GPRC5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50798
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.24731
Axon cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.82
HACD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83425
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.7935
Oligodendrocyte progenitor cell_Embryonic prefrontal cortex_Human	CellMarker Gene-Cell Type Associations	1.0	null
hsa-miR-208a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GMCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18852
FOXA1-25329375-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.298731
LIVF001-027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02828
GTEX-X261-0011-R8A-SM-4E3I5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2073
root	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071684
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6132-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22167
ZNF778	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91033
BRD-K49961249	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0018
GSE137325_3_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CKAP2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28762
SNU16	DepMap CRISPR Gene Dependency	1.0	5.9166
Charcot-Marie-Tooth disease dominant intermediate C	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.086
BRD-K39256324_-666_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
outer CP in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02145
TNFSF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69167
GGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13938
plumule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061586
outer CP in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.933649
mumps	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.514571
GTEX-V955-2026-SM-3GAFA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926094
hsa-miR-3672	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.888806
BRD-K71216961	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53184
GTEX-S7SE-0011-R6A-SM-2XCD9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910801
BRD-A11678676_Wortmannin_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.811
PDAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25968
ABAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96371
GSE169205_3_v_2_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Tentacle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.932
BRD-K20368781	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2954
Trophozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.082
BFAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36672
VSIG4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00604594
NDUFB7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00402194
SLC6A15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44948
MALME 3M	BioGPS Cell Line Gene Expression Profiles	1.0	1.71973
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41829
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8061-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ulcerative colitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.763
NUP35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31839
Eggshell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.093
olfactory lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
ARHGAP15	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00546868
TUBA4A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00695795
Vascular smooth muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.538
GTEX-U8T8-0008-SM-4DXSP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
PIKFYVE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18713
BRD-K77214780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.84972
AP4B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83632
nucleus	GO Cellular Component Annotations 2023	1.0	null
ZNF469	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9927
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.136
CDR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14686
BRD-K70856965	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44872
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.918054
ALDH1A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00650806
KG1	CCLE Cell Line Gene CNV Profiles	1.0	1.73872
CEBPD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07274
BRD-K92712225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92735
denatonium benzoate-5061	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Charcot-Marie-Tooth disease type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.393
hsa-miR-3689e	TargetScan Predicted Conserved microRNA Targets	1.0	0.37496
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6622
Prostate adenocarcinoma_PRAD_TCGA-G9-6369-01A-21R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KNS42	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35634
AMY2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00668961
GTEX-X4EO-0126-SM-3P5YN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40343
Neuromuscular disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
GTEX-R3RS-0626-SM-48FE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
GTEX-O5YV-2026-SM-2D7VS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
USP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71062
spermatogonium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.171241
HCC1419	COSMIC Cell Line Gene CNV Profiles	1.0	2.24845
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939047
EDNRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1381
hsa-miR-4419b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Prostate adenocarcinoma_PRAD_TCGA-HC-7742-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.926622
LIN37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35285
DGKI	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00393152
PAPLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44493
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.551
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9901
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.6138
ZGLP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00675173
BATF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24479
SRRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68092
EMTOKA	DepMap CRISPR Gene Dependency	1.0	3.33241
GTEX-PX3G-0926-SM-48U12	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
Invertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.998
NRBP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0102314
lipid transport	GO Biological Process Annotations 2023	1.0	null
NCIH1666	DepMap CRISPR Gene Dependency	1.0	10.4076
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11479
Organ system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
BRD-K40782193_QX 222_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-4478	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
BRD-K34910830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.37517
hsa-miR-4764-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
CTTNBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76967
EGI-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.083405
griseofulvin-7363	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-X4EP-0726-SM-3P5YJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35554
MTERF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65782
TMX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32482
16178058-Table5	GeneSigDB Published Gene Signatures	1.0	null
NarGHI complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.532
Sodium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.199
cell periphery	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.24424
UBE2NL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6385
20460173-ImmPortAntimicrobials	GeneSigDB Published Gene Signatures	1.0	null
Charcot-Marie-Tooth disease type 4B1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.176
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.94682
IPC-298	GDSC Cell Line Gene Expression Profiles	1.0	2.51189
heart	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.542963
GSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.97
MAP4K4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58188
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19758
BRD-K50287215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0445
Appendiceal neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.251
MESD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75089
BRD-K66214486	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.45632
GTEX-QVJO-0011-R2A-SM-2S1QK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992388
ARHGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22357
LY2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.745218
BACH1-22875853-HELA-AND-SCP4-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K58644442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24875
Rectum adenocarcinoma_READ_TCGA-AG-3742-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CELSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58066
GRIN2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00809756
transport	GO Biological Process Annotations 2015	1.0	null
TIGD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17857
CYB5D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14458
hypotrichosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.171286
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV5-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXD10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7449
SKMEL28	BioGPS Cell Line Gene Expression Profiles	1.0	1.15929
ABCF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58469
LRRC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67598
CACNA1F	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00862599
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6322
CRCGN015_HEPG2_48H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.81087
oculomotor nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06753
SAMD4A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00695983
hsa-miR-3651	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
SLC45A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89689
GTEX-QDT8-0011-R8A-SM-32PKE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995825
RASSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02015
SMARCA4-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ZNF443	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67201
TCTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87351
primary auditory cortex (core)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.882881
GTEX-SNOS-1626-SM-3NMA4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901826
Neostriatum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.23
HIGD1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48332
leflunomide-5884	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0935
organelle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.053776
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.83913
BRD-K07033348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18194
NCVADR RES	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.05947
FANCE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.622
FASTK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00740422
TAF1L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00858116
SNB75	BioGPS Cell Line Gene Expression Profiles	1.0	0.97735
GTEX-QEG4-1126-SM-2S1P7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59821
UBE2F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62849
TP53INP2_KO_GDS5053_277_mouse_Skeletal muscle - SKM-KO	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ADGRL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69737
GSE249544,GSE249637_9_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BCOR-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.973621
outer CP in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.5856
TMSB4Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88702
RERFLCAD1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.78886
GTEX-UTHO-0011-R4A-SM-3GIJP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913354
PMC9396374-Table_5.XLSX-Table_S5-AR_genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4330	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.11864
NBAS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00580747
HCC2935	CCLE Cell Line Gene CNV Profiles	-1.0	-1.83397
hsa-miR-567	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
496100553_TCx_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.2979
BRD-A19500257_geldanamycin_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.174093
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBE3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28077
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08538
hsa-miR-485-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.32519
GSE162892_4_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
XAB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65916
Frequent Falls	DisGeNET Gene-Phenotype Associations	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05123
hsa-miR-548s	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
CHMP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5238
Neuroma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.924
H3K4me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Bursa copulatrix	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.81
GABRG2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00632454
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05768
ACVR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26718
NCR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00467093
liver	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.664775
PMC4595011-pgen.1005555.s003.xlsx-BPTF_DOWN-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
FOXH1-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
THAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33347
SLR23	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48086
BRD-K69491845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56179
SARS-BatSRBD_Day4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.83639
TRPC4AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2479
telencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BRD-K06900263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57151
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CXCR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75403
FZD9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00464448
BRD-A45889380_QUINACRINE HYDROCHLORIDE_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-XAJ8-1026-SM-47JY9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.906987
sulfadoxine-3547	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
pimosertib	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20093
PRR11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22388
UBA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0093206
BRD-K68705041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33189
CRCGN015_MCF10A.TP53.M_24H:D14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0309
TIMM8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55384
CYP2A6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00421209
MYC-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PRRX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69979
NRAS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00522167
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
invertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.10889
IFNL3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00576143
VSIG10L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35089
alveolar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.18331
PMC9519628-mmc2.xlsx-GSC_NSA-Name_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XV7Q-0008-SM-4BRWL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858992
GTEX-XQ3S-0001-SM-4B64K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.956951
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.22233
MYBL1_KO_GDS4485_349_mouse_Testis from 14 day old	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
TRAF3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00466736
oseltamivir-phosphate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12621
Myelinating Schwann cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.919
Juxtaparanode region of axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.755
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GTEX-WWYW-0011-R8A-SM-3NB3S	GTEx Tissue Sample Gene Expression Profiles	1.0	2.15947
BRD-K13049116_BMS-754807_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-7-5p	MiRTarBase microRNA Targets	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8408-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Pituitary	GTEx Tissue Gene Expression Profiles 2023	1.0	1.71165
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MORN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00890438
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15859
BRD-K60848736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15442
GTEX-XV7Q-1426-SM-4BRWA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
EPX	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00687068
including	GeneRIF Biological Term Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F1-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K51697315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71424
DIP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15977
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.78614
RTP5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00869762
SBK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00556401
GTEX-PX3G-0826-SM-48TZS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
voltage-gated potassium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.797
GTEX-X4XX-0011-R2A-SM-3P623	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28958
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4FB-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-V955-2426-SM-3GAEF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
HEC50B	DepMap CRISPR Gene Dependency	1.0	2.72895
MUL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63333
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.6758
BRD-K07300437	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79641
hsa-miR-4689	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
MARCHF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38745
SPRR2F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57296
hl-60 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.59124
CDX2-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066226
jm2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.76
myelin	GeneRIF Biological Term Annotations	1.0	null
GTEX-S341-0626-SM-4AD5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4642-01B-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8881251-18_2022_4183_MOESM3_ESM.xlsx-ERM_vs_P4-DEGs_ERM_versus_P4_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NL3H-0011-R7a-SM-2I3G5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995326
Leukodystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.08
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29W-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NOBOX	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00610728
Meningitis	DisGeNET Gene-Disease Associations	1.0	null
PDCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82919
Purine nucleoside phosphorylase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.063
TTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89672
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.873051
C15orf62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87071
GLRX2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00484765
BRD-K08428488	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45202
Ganglion	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.442
UQCRQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78244
FOXA1-27270436-CHIP-SEQ-PROSTATE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
Eye-muller cell	Tabula Sapiens Gene-Cell Associations	1.0	3.51874
BTG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54781
SOWAHC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00651467
charcot-marie-tooth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.653671
GSE171352_2_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
Type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.343
CDK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59776
methapyrilene-6644	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
small molecule binding	GO Molecular Function Annotations 2015	1.0	null
Cingulate gyrus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.119
GTEX-S341-0726-SM-4AD5R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QY-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vaginal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.647
BRD-K73824630_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TEX45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14495
ZNF287	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7194
HRAS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00499836
OGA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00661147
BRD-K53458780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59506
internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.329727
GSE89057_0_v_1_sox5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23391
FLI1-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
KDM4A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00603707
Cervical canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.506
GTEX-PWCY-1326-SM-48TCU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.268511
PMC5637904-PATH-243-193-s016.xlsx-human_up_in_fat_SOX11-Table_S5A_Upregulated_genes_in_tumours_from_DCIS-SOX11_cells_compared_to_DCIS-lacZ_cells_injected_into_mammary_fat_pad_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-3.31006
STX4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00673734
CAL-54	GDSC Cell Line Gene Expression Profiles	-1.0	-1.96773
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	1.0	0.920233
hsa-miR-4679	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
BRD-K42126874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09379
nerve	GTEx Tissue Gene Expression Profiles	1.0	1.60306
LIMD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30301
hsa-miR-645	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GTEX-NPJ8-0011-R2a-SM-2TC6M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905598
HES6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33827
SEL1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11768
RICTOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52878
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RRP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32243
PDCD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32813
TIGD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00787373
PIK3C2G	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00484669
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.376494
GTEX-R45C-0008-SM-48FF2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
intestinal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.098544
aerial part	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.330094
rumen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.222224
BRD-K79529972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27274
BRD-K44760023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66879
GTEX-XOTO-0326-SM-4B66K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23092
UNC50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39924
GTEX-TKQ1-1326-SM-4DXU7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48324
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R7-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STK35	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00574096
outer CP in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.833052
primary auditory cortex (core)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.868092
GTEX-SSA3-0526-SM-32QPL	GTEx Tissue Sample Gene Expression Profiles	1.0	2.07708
lip	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.855891
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.11243
A172	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.975119
Ar	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.4546
GTEX-PLZ6-1726-SM-2S1O6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37499
Parasympathetic ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.656
CCND1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00692328
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.870798
Neurilemmoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
GTEX-WVLH-0011-R4A-SM-3MJFS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14837
H3K27ac_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SSC4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29846
MTMR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56611
VASH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81614
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
Prostate adenocarcinoma_PRAD_TCGA-KC-A4BR-01A-32R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K79555018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87224
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0957
CRCGN015_MCF10A.TP53.M_24H:I04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.16732
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.619814
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9929
mRNA_ZFX_17448993	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
BRD-K69082321	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20417
PMC12022000-JCMM-29-e70533-s003.pdf-0-SOX11_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.863115
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15546
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01048
GTEX-X261-0326-SM-3NMD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
BRD-K85066228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.722
BRD-K76908866_CP-724714_MCF7_3_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00548879
type ii diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.428019
ZFP91	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00509739
GTEX-WHSE-0011-R2A-SM-3P5ZL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04764
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1569
GTEX-WHSE-0011-R3A-SM-3P5ZM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858665
Hypomyelinating leukodystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.121
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7097-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCH	DepMap CRISPR Gene Dependency	1.0	5.45913
vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.050678
BRD-K90999585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04558
THEM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72522
BRD-A06837695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20011
d94	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.29
outer CP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22868
GDF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33704
BRD-K43936610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06995
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.839343
UBE2F	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0087421
MEOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15308
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.8651
BRD-K37719063	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62375
tonsil	HPA Tissue Gene Expression Profiles	-1.0	-0.847178
Microsporidiosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.144
GTEX-QMR6-0011-R2A-SM-32PKV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55464
NCIH1781	CCLE Cell Line Gene CNV Profiles	-1.0	-2.15875
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.40988
Brain Lower Grade Glioma_LGG_TCGA-DH-A669-01A-12R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NANOG-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SLFN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16626
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.25534
Acute Myeloid Leukemia_LAML_TCGA-AB-2849-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K86848211	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15495
BHT101	CCLE Cell Line Gene CNV Profiles	1.0	2.36413
P63-20808887-KERATINOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CALHM6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0068631
CDC42	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0041144
lymph node	HPA Tissue Gene Expression Profiles	-1.0	-0.847178
KBTBD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23411
SPINT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3235
GSE133661_0_v_1_c19orf12_human	RummaGEO Gene Perturbation Signatures	1.0	null
Charcot-Marie-Tooth disease type 1A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.315
NAA60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49021
GTEX-Q2AG-0011-R9A-SM-2HMJ6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56332
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
hsa-miR-216b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
STOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64437
BRD-K43186783	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12201
H2AC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8066
Main axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.474
POU1F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74068
lymph node	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.271256
DBNDD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78191
TRDMT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00669995
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040886
MSTN_DEPLETION_GDS3637_94_mouse_mature skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
FSCN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00624693
NCI-H1944	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27502
EPN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24769
DCTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68075
BRD-K29673910	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0104
GTEX-P4QS-0008-SM-48TDY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
NMYC-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PI4K2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00519432
BRD-K91263825_NORTRIPTYLINE_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K57464717	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.02612
Asi complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.814
CCDC50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51726
CREB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94741
GTEX-QMR6-0011-R4A-SM-32PKU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27806
GTEX-XV7Q-0226-SM-4BRVL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.977
Attachment organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.544
PMC5409051__F5	PFOCR Pathway Figure Associations 2023	1.0	null
sucrase-isomaltase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.694
NMU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32621
Demyelinating polyneuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.78
KAP1-22055183-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K26195700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97057
GTEX-OHPN-0011-R4A-SM-2I5FD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.96893
SEL1L3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0112069
CAMKK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00558814
LRP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19588
GTEX-QMR6-0011-R5A-SM-32PKT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1156
PMC7857731-elife-63093-supp1.xlsx-DEG_MITF-X6vsEV-SkMEL28-Unnamed_2_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06385
Encephalitozoonosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.495
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A42Z-01A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068745
ICC137	DepMap CRISPR Gene Dependency	1.0	2.97651
BRD-K63587749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09293
GTEX-XPVG-2826-SM-4B66J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.985285
ST13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93631
GTEX-XUW1-0005-SM-4BOQ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
BRD-K89997465_CHLORPROMAZINE_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MACC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08599
gonad	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.41848
HCC4006	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61839
GTEX-NPJ8-0011-R9a-SM-2YUN5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39524
POU2AF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11033
GTEX-W5X1-2826-SM-3GILM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865493
CRCGN011_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.304
internal segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11184
dermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.140238
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11054
TNFSF9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00735094
CXCL10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00676845
RBM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13269
GTEX-WFG7-2426-SM-3GIL2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903612
EXOC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04491
inferolateral temporal cortex (area TEv, area 20)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.892091
COL8A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47628
ERI1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00710593
AGAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63847
CORL105	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51268
toxin-antitoxin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.996
BRD-K29950728_CLOMIPHENE CITRATE_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
shoot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057271
LDAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07479
GTEX-TKQ1-0008-SM-4DXSO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877514
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.832804
cerebral lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
RAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17238
MTCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91853
Brain myelin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.425
BSG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45139
hsa-miR-548d-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN008_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.1746
GTEX-UPIC-0002-SM-3NMDC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.936606
CRCGN016_MCF10A.WT.HP_24H:O13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0535
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A4ZQ-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DUSP23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41647
NCIN87	DepMap CRISPR Gene Dependency	1.0	7.09155
BRD-K30863464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0274
Colon transversum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.762
CRCGN017_MCF10A.WT.HP_24H:E04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.03438
AKR1C3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0041835
CRCGN015_HEPG2_48H:M22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.07485
BRD-K03848296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12781
EFNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24505
FCGR3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00728859
NET1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93778
GTEX-NL4W-0011-R10A-SM-2I3DY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34375
GTEX-UTHO-0011-R3A-SM-3GIK8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910258
ADGRE5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74709
Tumor Cell Invasion	DisGeNET Gene-Phenotype Associations	1.0	null
IL5RA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00609941
BRD-K93316985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12688
Perturb_6494_KD_PIEZO1_SRP392492	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BTRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44794
ALDH3A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00644812
EIF3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23091
A-VN-1203-2004(H5N1)_Day2-10^4pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.82263
GTEX-U3ZH-0008-SM-4DXT2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
HNF4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92223
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9348
BRD-K24965236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.79379
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.874919
PMC4521181-oncsis201520x8.pdf-112-SPDEF_SPDEF	Rummagene Transcription Factor Associations 2026	1.0	null
CXCL9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00632838
MANEAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89617
Etoposide	CTD Gene-Chemical Interactions	1.0	null
P53-22387025-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
mp14	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.716
outer CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.93222
Lipid storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.07
BRD-K89391146_RG-108_HA1E_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05413
BRD-K94301203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5623
TLE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33306
GTEX-R55E-0426-SM-2TC65	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90466
Insect labium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.541
GLYATL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60813
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.365
MAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62474
GMFG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00549212
hsa-miR-3128	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
PMC5993422-NIHMS922534-supplement-Sup_Tables_1-23.xlsx-RELA-EnhancerAssociatedGene-Unnamed_3_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.188274
GTEX-P4QT-0008-SM-48TDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
TIFAB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0053792
BRD-K90902537	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5836
IRF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00742421
GSE213588_8_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A52660433_Tetrindole mesylate_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7691-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Night sleep phenotypes	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.51549
HEC50B	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48345
GTEX-WYJK-0326-SM-3NMA8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965209
NRF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-548p	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-RWS6-0426-SM-47JXH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
transporter activity	GO Molecular Function Annotations 2015	1.0	null
MEOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80627
GTEX-RWS6-0926-SM-47JXE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
CDKN2C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00580921
FBXL14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21048
GTEX-XBED-0008-SM-47JWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
Acoustic neuroma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.005
Erythrocytic stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.117
HS6ST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94448
COLO818	CCLE Cell Line Gene Expression Profiles	1.0	1.75451
TENT5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13383
BRD-K91191855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04205
HOXA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40803
GTEX-S32W-1226-SM-4AD67	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
ESO51	COSMIC Cell Line Gene Mutation Profiles	1.0	null
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.962225
GTEX-SN8G-0008-SM-4DM4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872622
BRD-K88625236_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SPG11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73123
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23805
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.278
Central nervous system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
GTEX-XPVG-0008-SM-4GICH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.927183
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.09253
hsa-miR-4470	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
phthalylsulfathiazole-5249	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
outer CP in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10374
SLC35E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24466
DCAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90521
Ensheathing process	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.708
viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.058105
TE-5	GDSC Cell Line Gene Expression Profiles	-1.0	-1.42126
mp5	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.052
PIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68974
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.028026
jejunum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.186448
SPTBN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00712273
RNF31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09561
CRCGN009_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.91595
GET1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09568
hsa-miR-4699-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.9535
Microsporidian	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.826
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2012
LU-99A	COSMIC Cell Line Gene CNV Profiles	1.0	2.24845
CDC25A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0039336
lateral parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.84978
extracellular vesicular exosome	GO Cellular Component Annotations 2015	1.0	null
GTEX-NPJ7-0011-R2a-SM-2I3GF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951379
SDHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58902
PRPS1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39904
GTEX-VUSG-2726-SM-4KKZJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26438
primary spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.183038
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.65754
CKMT2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0039462
COX4I1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00508253
Motor neuron disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.183
RAGE_knockout_268_GDS3755	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.99529
GSE249544,GSE249637_6_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PNN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61289
SNU1327	DepMap CRISPR Gene Dependency	1.0	4.08111
Nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.133
primary auditory cortex (core)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06228
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.00337
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11027
alveolar cell type ii	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.248683
PMC10311050-mmc2.pdf-40-TBX2-AS1_TBX2	Rummagene Transcription Factor Associations 2026	1.0	null
SLITRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73152
medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.35021
SNU-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.960915
MZT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74508
GTEX-X4EO-0926-SM-3P5Z2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00572
NCI-H820	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MPLKIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.94046
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.25619
SERF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37184
JAG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00669466
RTN4RL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36192
MMP19	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00600626
VPS18	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00606927
496100323_FWM_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.35719
GTEX-OHPN-0011-R3A-SM-2I5FC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.13666
AP1G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85879
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5703-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RVPU-0011-R9A-SM-3NM8E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54331
GTEX-XUZC-1726-SM-4BRWS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
ZIC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73269
CAMKK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00616822
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.209
hsa-miR-3915	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
PAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60924
GTEX-S33H-2326-SM-2XCB3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47996
SP110	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0059375
USP42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27752
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A71U-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UACC62	CCLE Cell Line Gene Expression Profiles	1.0	1.86789
ATP1B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26008
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
Neuropathy	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
SCNN1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63805
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.84301
PMC6870463-Table_7.xlsx-Family_H_No_LPS-Untreated_BMDMs_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
WHRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99069
RDES	DepMap CRISPR Gene Dependency	1.0	2.60611
SFTPC_KO_GDS4876_476_mouse_Lung Type II cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.225144
AP1S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20651
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.28341
GTEX-NPJ8-0011-R5a-SM-2HMJY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936421
DLD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63467
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.434
E2F7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0107575
GLI1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00724626
PPIF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0065963
TFF2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00756718
EGR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00329501
hsa-miR-599	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
496100598_PCx_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.39006
GSE213588_8_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ARIH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17187
COTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47196
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.24661
Kidney Chromophobe_KICH_TCGA-KO-8415-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATP13A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36777
PAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7457
GRB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0062319
GTEX-NL4W-0011-R4a-SM-2I5GZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4652
RVH421	CCLE Cell Line Gene Expression Profiles	1.0	1.45304
frontal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
flight muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.31333
TNC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00677935
POGLUT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80027
ALOX5AP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00730106
CRCGN014_HEPG2_24H:I24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.05709
KAT8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00490034
LST1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00533869
PCDH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10759
Nuclear receptors meta pathway	WikiPathways Pathways 2024	1.0	null
FOXD4L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53311
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7071-01A-12R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DBH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0080181
ELF5-23300383-T47D-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CALCA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00454527
CRCGN015_HEPG2_48H:B21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.25232
SP140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46128
extracellular region part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K07525144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48207
MAP3K1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04707
Acute Myeloid Leukemia_LAML_TCGA-AB-2838-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QDT8-0011-R2A-SM-32PKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977231
RIPOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11223
OGFOD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00513664
ITGAV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86926
Brain Lower Grade Glioma_LGG_TCGA-R8-A6MK-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
minoxidil-4216	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RAB25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65012
BRD-K60719499	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15947
PTPN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07299
BRD-K18416855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03888
GTEX-QDT8-0011-R1A-SM-32PKS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896507
HDAC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00548762
Hereditary sensory neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837676
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.956527
Basal ganglion	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.442
LY86	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00675232
Charcot-Marie-Tooth disease type X	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.664
BRD-A75409952_wortmannin_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZNF302	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4329
GPR25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34926
RAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43237
VPREB3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00519801
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92201
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.93258
ZNF493	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25557
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.565
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.13017
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.071
GTEX-XUJ4-2626-SM-4BOQ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
Charcot-Marie-Tooth disease type 2D	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.25
BRD-A84481105_thioridazine_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
spinal root	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.661523
RNF139	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55035
NCI-H1703	COSMIC Cell Line Gene Mutation Profiles	1.0	null
testis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.445268
tocainide-4256	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A71R-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USP4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00548562
intracellular part	GO Cellular Component Annotations 2015	1.0	null
RHOB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06149
measles	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.344207
PSN1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.938943
mp12	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.843
GGNBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41774
molecular layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.922773
lateral hypothalamic area, tuberal part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.886736
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
GTEX-PSDG-0008-SM-48TE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.1787
plant embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06046
BRD-K95901403_S1118_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
membrane coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.10441
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.36
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.38811
S-Hydroxycysteine	DrugBank Drug Targets	1.0	null
OVSAHO	CCLE Cell Line Gene Expression Profiles	-1.0	-1.67277
principal sensory nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.33693
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.68788
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.663
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
P2RY12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00633289
SETDB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00534604
ACTR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60119
HYOU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76707
RBBP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91647
D283MED	CCLE Cell Line Gene CNV Profiles	1.0	1.77319
MOLM13	CCLE Cell Line Gene CNV Profiles	1.0	1.40868
IMPA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0111547
SW1710	GDSC Cell Line Gene Expression Profiles	-1.0	-1.85122
GTEX-RVPV-0008-SM-47JYW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90466
GTEX-U8XE-0526-SM-3DB8R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09394
COL2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34989
TSPAN14	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00760548
cholesterol binding	GO Molecular Function Annotations 2023	1.0	null
KLF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27464
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.232
LTBR_INHIBITION - 1 Day_GDS2005_728_mouse_Lymph nodes  (MG-430B)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4643-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K47598052_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K81463178	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38404
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.627
GCH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00549718
GTEX-Q734-0008-SM-48U2I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.48139
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5987-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GPR25	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00708081
TOR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81921
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.935568
cytoplasm	GO Cellular Component Annotations 2015	1.0	null
BRD-K42150052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31513
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZNF354B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55048
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
CRCGN008_HEPG2_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2097
MCMBP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00430319
NEK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00646787
LATS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05902
B4GALT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12086
extracellular vesicular exosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K99616396_HY-10228_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
B800-820 antenna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.539
RT4-D6P2T cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.731
GTEX-RWSA-0008-SM-47JYX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
Internode	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.378
GTEX-XLM4-0011-R9A-SM-4AT45	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45862
SERPINA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0063592
PMC4407272-elife06857s002.xlsx-Hermes_BRG1-MITF_ComDown-List-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4328	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GTEX-S4Z8-0526-SM-4AD4T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
NoRC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.788
KCNC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00673771
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1819
NDUFB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76777
GTEX-WHWD-2326-SM-3LK6Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18497
GTEX-RNOR-0326-SM-2TF51	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40865
GTEX-POMQ-2026-SM-2S1OD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15434
BRD-K44458042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58334
hsa-miR-4524	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
PTPRC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00553655
SLFN12L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00655452
GTEX-P44H-1126-SM-48TBU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
hsa-miR-3121-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
BRD-K34117117	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22047
NRF1	ENCODE Transcription Factor Targets	1.0	null
MAP1LC3B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98488
cholesterol binding	GO Molecular Function Annotations 2025	1.0	null
CRCGN015_HEPG2_48H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.70437
19523942-Table2	GeneSigDB Published Gene Signatures	1.0	null
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.918684
GSE213588_8_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-P44H-0011-R8A-SM-2XCEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02542
BRD-K85985071_E3380_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.414
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00067
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883766
Distal tip cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.705
BRD-K12906962_DICHLOROBENZAMIL_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5008-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHAGOK1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.01303
SORD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86667
HSD17B10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00325065
GSE236486_1_v_2_arnt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Bacterial vaginosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.103
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A110-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4481	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
flunixin-4273	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XQ3S-0008-SM-4GIDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
MAD2L1BP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00461206
NUTM2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00750736
CRCGN015_HEPG2_48H:G04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.01169
GTEX-XQ8I-0526-SM-4BOPS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857643
pimasertib	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55185
KYSE-450	GDSC Cell Line Gene Expression Profiles	-1.0	-1.94363
hsa-miR-411	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
hsa-miR-501-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GTEX-PWO3-0011-R8A-SM-2I5GD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958109
CHL1	CCLE Cell Line Gene Expression Profiles	1.0	2.37656
Autoimmune disease of central nervous system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.305
BTN3A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00561722
Ebolavirus(ZEBOV)_3day_PBMCs_rNAPc2treated_21987740_GSE24943	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-0.085097
hsa-miR-3691-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
BRD-K49865102_PD-0325901_A375_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MT1M	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0048661
DPF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00467136
600MPE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.58659
UBFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68864
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06085
SAS	GDSC Cell Line Gene Expression Profiles	-1.0	-1.81055
Alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.132
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
SHMT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00592624
NS-0 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.878
Charcot-Marie-Tooth disease type 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.196
OSC19	DepMap CRISPR Gene Dependency	1.0	5.53683
AKR1C2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00592577
ZNF735	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03014
BRD-K49159670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45618
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.4938
BATF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00811551
Olfactory bulb	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.38
CDKN1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00904088
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26278
GTEX-TKQ2-0008-SM-4DM5L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
hsa-miR-548z	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
CTSF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00576596
TCL1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6009
GTEX-XUJ4-1026-SM-4BOPB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
BACH1-22875853-CHIP-PCR-HELA-AND-SCP4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MZ2-MEL	GDSC Cell Line Gene Expression Profiles	1.0	1.63998
HdhQ111/111_Knock-in_GDS4534_744_mouse_Striatum and cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.858589
Mesosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.921
ISHIKAWA(HERAKLIO)02ER-	COSMIC Cell Line Gene CNV Profiles	1.0	2.24845
HSD17B7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00549112
opportunistic mycosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.782298
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ZEB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0072387
LRRC57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73521
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.320591
MINDY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99218
GTEX-SJXC-0008-SM-4DM7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
GTEX-Q2AI-0008-SM-48U2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
PRDX2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00570314
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4622
BRD-K62888534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80607
SH-EP1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.746
Adductor brevis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.578
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059095
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.13151
GTEX-QEL4-0008-SM-447AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
hsa-miR-200a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
BRD-K10017294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18123
H3K9ac_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
sc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.803
VI	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18947
COA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10489
HCC1428	CCLE Cell Line Gene CNV Profiles	1.0	1.91208
FUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90987
BRD-K34014345_-666_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MEX3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29703
HBQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09713
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.90319
COPG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92505
TMEM129	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82161
FBXO32	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00554015
hsa-miR-192	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
PYHIN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00651428
Sphere organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.083
ALPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3599
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11546
Parallel actin filament bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.147
GTEX-V1D1-0008-SM-4JBIJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35856
ARHGAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37029
TP53	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-QDVJ-0008-SM-48U2E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.871854
APP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63123
OAS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00580897
GTEX-NPJ7-0011-R4a-SM-2I3GJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836534
ZBTB14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59567
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7920-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
erythrocytic stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.226411
RCCFG2	DepMap CRISPR Gene Dependency	1.0	4.64959
ORC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29707
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0