association	dataset	threshold value	standardized value
NFAT5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00923119
BRD-K75092094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14361
PSKH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00400949
BRD-K28752165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.13821
GLUD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00560022
BRD-K78847404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10535
NUDT19	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00771712
KYNU	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00874993
NAMPT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00321332
496100559_FWM_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.02574
GSE183335,GSE183351_1_v_0_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE242290_1_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE197948_2_v_1_atp7b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K53094498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30991
CRCGN015_MCF10A_48H:M22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.60145
GSE149903_0_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FDX2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00527755
ARG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00563099
chr19_46471049_A_C_b38	GTEx eQTL 2025	1.0	3.88318
BRD-K04371719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79269
TLR5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00695737
BRD-K79147587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11787
GSE191105_2_v_3_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE178340_5_v_3_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE173262_6_v_0_ash1l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K17122162	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37346
aclarubicin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20668
GSE205976,GSE205978_2_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0302
GSE153757,GSE153758_1_v_3_ftsj1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE164874_5_v_12_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K21695872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53748
308_ANAPC4_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.576064
GSE48812_8_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NACA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00665034
Pancreas	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.681358
H2BC15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0415
N4BP2L1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00776126
GSE160304,GSE163392_4_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
6709_PPY_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.525901
5074_MIIP_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.547649
PAICS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00382889
BRD-A36171447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19614
BRD-K83189379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04262
TRAPPC13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0078206
CD63	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00661482
BRD-K02602127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31118
CALU	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00409494
ARFGAP3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00480823
CYP1A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00838028
GSE245270_2_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7870953-41540_2021_169_MOESM9_ESM.xlsx-SALL2_targets-target_gene_SALL2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K46412655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1502
GSE109140_2_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE102467_3_v_2_pazopanib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE126345_4_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE118077_7_v_8_sprr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:J19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.42775
GSE205976,GSE205978_1_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DLD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03254
GSE239844_7_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HES5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0944
BMX	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0078293
ROBO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00662438
BRD-K59046641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12974
CRCGN015_HEPG2_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.0525
PDE3B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00489355
NCIH358	DepMap CRISPR Gene Dependency	1.0	2.15255
GSE210101,GSE210114_11_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148200_0_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ACE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0061793
PMC4954754-elife-15550-fig3-figsupp1-data1.xlsx-HSF1_Genes-Unnamed_18_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
SDF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42023
GSE229344_1_v_0_cyb5r3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE253795_1_v_0_alkbh5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE101239_5_v_0_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE102505_6_v_2_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE180321_0_v_1_imperatorin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.9166
R3HDM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6081
BRD-K05185748	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19166
GSE169205_0_v_8_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LIVF001-022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54012
G0S2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00523136
ITGAV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59866
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.46041
CRCGN016_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.92437
CD1E	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00581205
RALB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53796
BRD-K98969488	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21377
PARK7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0050146
MAP2K7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1759
ANKRD33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18716
POLE2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0047234
TNIP3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00875599
KCNQ3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00638352
CAD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00523782
GSE163297_0_v_2_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9537523-41467_2022_33364_MOESM7_ESM.xlsx-scores_wilcoxon_1_MONTH_ORG-EN2_n_EN2	Rummagene Transcription Factor Associations 2026	1.0	null
POPDC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00586925
BRD-K36115176	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07352
ACTR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00764841
ZMAT3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00579389
AGMAT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00854297
GSE153836_14_v_5_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZBTB32	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00591787
GSE200673,GSE200691_2_v_0_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Forebrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
LS411N	DepMap CRISPR Gene Dependency	1.0	5.13991
GSE174498,GSE174500_3_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE144231_4_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GCM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9093
GSE229344_2_v_0_cyb5r3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE242290_3_v_2_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2643
NLRP7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00747327
GSE102598_1_v_2_nmda_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.49409
BRD-K25583354	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60024
BRD-K73802986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79759
CHRNB3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00501703
GSE195559_0_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PLCB3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00362546
GSE101336_1_v_3_decitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE174418,GSE174421_2_v_3_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K11188962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08271
GSE131377_1_v_3_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ATP2A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00392576
HCK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00400004
ABT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73069
NPTN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00414873
GSE232714_0_v_1_raver1_human	RummaGEO Gene Perturbation Signatures	1.0	null
AXIN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00930843
CARD9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00686104
ANGPTL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00585631
chr19_46472263_C_T_b38	GTEx eQTL 2025	1.0	7.1741
GSE214514_1_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE234340_9_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.2821
pi1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.51
GSE207611,GSE207612_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GLMN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58443
HAL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00689557
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_HEPG2_48H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.91228
CFP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00681406
GSE140937,GSE140938_0_v_2_slfn11_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.18487
GCM2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5979
PMC10760404-NIHMS1688779-supplement-Supplementary_Table_S6.xlsx-EMP_CREB_Targets-symbol_CREB1	Rummagene Transcription Factor Associations 2026	1.0	null
CUL3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00538085
GSE88819_3_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE174701_1_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE153836_14_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MAP4K2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0071903
GSE132369,GSE132371_5_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	1.0	null
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2524
PABIR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00630134
GSE226285_3_v_1_nr0b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE232558_0_v_2_fbxl12_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K55434198	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52451
BRD-K63921431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17513
BRD-A57353172	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71031
GLIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.9962
CTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60521
GSE195663_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
COX7C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00596816
BRD-K60393413	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30714
MGAM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00767163
BRD-K62612761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30589
BRD-K22875057	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15752
ZNF451	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63515
RFC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3513
CRCGN015_HEPG2_48H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.22452
GSE245270_1_v_5_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
SPINK5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00608728
MARK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1423
PFKP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00653543
TWF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00709451
CRCGN011_HEPG2_24H:D13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3393
NPRL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00560302
CRCGN015_HEPG2_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.62288
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_ZSCAN4-Unnamed_1_ZSCAN4	Rummagene Transcription Factor Associations 2026	1.0	null
PRDM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00549126
COX4I1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99012
GSE182179_5_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
TREML4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00699544
AUTS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00601264
BRD-K08570368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42599
SLC15A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00475663
YARS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00612748
GSE140441_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KIR3DL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0057163
BRD-K84210390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42455
GSE234340_12_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE217363_4_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3136
CRCGN015_HEPG2_48H:H04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25104
TM9SF4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00491108
GSE120612_4_v_3_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE153867_6_v_3_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KLRK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00775378
RIEG2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00713795
BRD-K53802078	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09931
GSE219195_1_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
ACSM5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00511477
TMEM183A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51833
SNU2535	DepMap CRISPR Gene Dependency	1.0	2.2825
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K86845405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22263
GSTA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00558516
GSE239688_2_v_3_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Uterine cervix	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SMIM29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57464
GSE214931_4_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ATP4A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00548373
GSE142684_3_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K15318079	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06906
GSE203429_0_v_1_angptl8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TMEM163	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00552383
USP46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37704
SNCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05367
BRD-K46970272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28225
GSE148200_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE112761,GSE112767_4_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE118765_1_v_5_rreb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VN1R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06746
Artery - Tibial	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.581264
GSE215351,GSE215794_1_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
P2RX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00728416
BRD-K06313694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60299
BRD-K89679058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20244
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.0203
MYD88	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00648097
BRD-K16789950	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10718
BRD-K13299646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27469
GSE176008_7_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE167373_0_v_3_rbfox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE195559_8_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K99903568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17181
NIPSNAP3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42824
GSE149035_3_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-HIF1_HIF2_miRNA_targets_DMOG-Unnamed_1_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE128730_0_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE213588_10_v_7_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE166184,GSE166185_1_v_0_sox2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K60743396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.172
PMC4219345-1471-2121-14-52-S3.xlsx-BORIS_hNP1-Gene_Symbol_CTCFL	Rummagene Transcription Factor Associations 2026	1.0	null
RPS17	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00657002
TCF7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00723165
Oligodendroglioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.226
CRCGN016_MCF10A.TP53.M_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.34443
GSE226249_5_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
XRCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00982
GSE149366_1_v_0_sulconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ATP6V1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00634167
GSE133691_2_v_0_lgr5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8567138-Table_2.xlsx-Sheet1-IGFBP5_AND_IGFBP7_NOT_IGFBP3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
DMD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00663505
BRD-K30674856	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52027
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-OLIG2_UNIQUE_DYS_GENES-OLIG2_TLE_vs_TL_log2FoldChange_1_padj_0_1_OLIG2	Rummagene Transcription Factor Associations 2026	1.0	null
REL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00512045
TNFRSF18	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00525228
Sox3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.655
SHC4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00777304
GSE68925_1_v_0_fasudil_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EFNA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09
GSE175787_5_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE235550_2_v_0_hspa9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11602576-mmc11.xlsx-ST12-Table_S12_Output_of_mash_model_of_milk_and_GTEx_eQTL_effects_Related_to_Figure_2_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
RP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06989
SST	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0062694
DNAJC30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41233
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.4841
GSE176008_7_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6347712-pnas.1812449116.sd06.xlsx-iPSC_IRF7_48h_rest_RNAExpress-Gene_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
ACSL4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00791172
GSE234340_9_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K12281552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2477
GSE126345_7_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CBLIF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00770479
GSE242199_6_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K41731186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02883
PMC10319804-41467_2023_38747_MOESM9_ESM.xlsx-KHSRP_KD_genes_up-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K89637567	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67659
EMG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04393
BCL2L2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00435512
CRCGN015_HEPG2_48H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.46781
FCGR2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00456008
BTNL3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00879147
CRCGN015_HEPG2_48H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.37853
CRCGN015_HEPG2_48H:F16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.26815
pravadoline	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38742
Hippocampus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
WDR87	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0051921
5470_NAT10_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.77965
TTA-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.708
GSE174701_1_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216273,GSE216292_0_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE234340_4_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE101239_4_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH716	DepMap CRISPR Gene Dependency	1.0	2.40367
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.7
BRD-K07230804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53173
BRD-A99344113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98748
GSE210093_0_v_2_taf15_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TSPAN4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00495351
KIF18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15214
PIP5K1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00702818
BRD-K63169405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54687
CRCGN015_HEPG2_48H:M08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.52892
CHRNB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00632695
GSE119498_0_v_5_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K57315740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73467
BRD-K21982562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50296
GNG7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00811005
PRKAA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00639222
GSE175787_4_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
chr19_46471471_C_T_b38	GTEx eQTL 2025	1.0	3.96302
GSE158834_12_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAOA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00655614
PTPN4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00642561
TRA2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00398752
CRCGN016_MCF10A.TP53.M_24H:I20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.31522
KCNAB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00536718
GSE149903_3_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE195568_3_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9061835-41523_2022_425_MOESM1_ESM.xlsx-S3_Differential_GEX-Table-S3_Differential_expression_analysis_results_for_SOX10-high_versus_SOX10-low_TNBCs_from_the_TGCA_and_METABRIC_expression_datasets_SOX10	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_HEPG2_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.7789
FYN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00536027
BRD-K31325635	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21807
MMP23A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0054799
BRD-K62983405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03143
PMC4944136-srep28995-s2.xls-OTX2-gene_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE199606_6_v_7_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE201270,GSE201272_5_v_3_mybl2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K48059443	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46563
BRD-A76905089	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2423
BRD-K15879529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02475
Amygdala	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.445
SLC3A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00921851
SLF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2663
PUS10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00491783
BRD-K86838462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55525
RASAL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00755599
CRCGN017_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.8085
OGFR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00655727
PSMC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01697
HLA-DOB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0058217
BRD-A89575866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09198
BRD-K95871937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12574
GSE261563_6_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
OVTOKO	DepMap CRISPR Gene Dependency	1.0	2.01736
GSE180185_9_v_5_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210580_0_v_2_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K69543414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50976
LAIR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00694015
GSE178532_1_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CSNK2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00632828
NOS1	DepMap CRISPR Gene Dependency	1.0	2.32185
SEC23IP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00513206
BRD-K54834493	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11625
GSE240645_3_v_2_u90926_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4212256-mmc5.xlsx-FLI1_log2_results-MIR622_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K11516621	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39765
ADAMTSL3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00484384
BRD-K77892972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41048
PMC5989213-41467_2018_4462_MOESM8_ESM.xlsx-3-Supplementary_Data_3_List_of_2687_genes_differentially_expressed_between_SETBP1-G870S_and_Empty_293_FLP-In_lines_SETBP1	Rummagene Transcription Factor Associations 2026	1.0	null
RGS8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00684555
BRD-K87383650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31169
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SSTR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00594134
UCK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00556731
GSE242290_3_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11185845-NIHMS1996282-supplement-Table_S1.xls-TableS1_txt-CB_TBL1XR1_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
IL17RA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00926949
MYO1G	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00754087
BRD-K20807411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05333
CBX6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00485669
HUCCT1	DepMap CRISPR Gene Dependency	1.0	2.07649
MBNL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00697481
BRD-K74660272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11303
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.158
ABCA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00559076
GTEx Brain 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-12.5064
GSE231891_1_v_0_cdk8_human	RummaGEO Gene Perturbation Signatures	1.0	null
ARHGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88961
DIDO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0086619
TRPC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0117494
GSE129725_1_v_5_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
6446_PLEKHJ1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.800714
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.68451
DKC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00793839
H4C5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00530515
EIF5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00793382
PTGR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00859929
GSE144231_4_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K41241300	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.15431
ZBTB44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23167
CRCGN015_HEPG2_48H:A14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.29546
TPSAB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0120935
BRD-K54007898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15976
SEPTIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1547
GSE100528_1_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PALD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06305
PDS5B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0101451
BRD-K43834805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57261
GSE147056_0_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_ZSCAN4-Unnamed_2_ZSCAN4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE160083,GSE160084_1_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE199606_6_v_0_csf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K06614664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06814
RYR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00676031
PPP2CA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00645025
GSE242199_6_v_11_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.41735
PRL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00558757
GSE201309_4_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE245270_1_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SGK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00722357
5933_OGT_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.691988
CRCGN017_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.56729
BRD-K92524632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77961
CRCGN010_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.22155
BRD-K27050140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18509
Basal ganglion	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.445
EEF2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00592494
TGBC1TKB	DepMap CRISPR Gene Dependency	1.0	3.62448
GSK3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36284
NME4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.005775
PPP1R8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2799
GSE171572_1_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN013_HEPG2_24H:F09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.00453
CRCGN015_MCF10A.TP53.M_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.15095
496100611_FWM_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.66483
CRCGN015_HEPG2_48H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.70047
GSE226249_0_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.538
BRD-K61909412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38695
CXCL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00501697
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.5236
BRD-K63354944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12805
BRD-K43674766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33388
PMC9013128-NIHMS1795992-supplement-6.xlsx-ARID2_MUT_Dowregulated-Gene_name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
CXCL8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00563492
BRD-K22229373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00602
Brain - Caudate (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.654435
Nthy-ori 3-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.578
ATXN1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03549
LIVF001-023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.57309
BRD-K62182950	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85217
NPC1L1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00489138
SDC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00582034
GSE169205_3_v_2_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
PDXDC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00605613
ASCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02323
HEC1	DepMap CRISPR Gene Dependency	1.0	2.06673
GSE216043_10_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K22875065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83574
GSE234340_3_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EXT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00388323
BRD-K76910883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09298
NFE2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00838724
BRD-K61020385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42024
chr19_46471421_C_G_b38	GTEx eQTL 2025	1.0	15.2519
PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE226249_0_v_6_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PHACTR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00664487
NCAPH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00591212
BRD-K96575636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37672
JMJD6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00625491
BRD-K66821167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20881
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
LATS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00750088
TET2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40123
Corpus callosum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.028
NAGK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00678866
SETDB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00560433
SKHEP1	DepMap CRISPR Gene Dependency	1.0	14.2632
BRD-K65461993	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60432
GSE145323,GSE145324_3_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LCP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00483483
TP53INP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00649309
BRD-K07361992	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58813
RPS6KB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0107831
PMC11639743-mmc2.xlsx-LIN28B-gene_name_LIN28B	Rummagene Transcription Factor Associations 2026	1.0	null
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.25778
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	13.9995
GAK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00561064
BRD-K17686226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18228
GSE157555,GSE157556_0_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE102505_5_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-DMOG_-_HIF1A-gene_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07607
SARS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00607586
BRD-K58217579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29916
TM4SF5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00587125
CAMKK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00553685
ADRA1D	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00642731
BRD-K43905345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57459
DBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08968
BRD-K58245095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52162
GSE122425_1_v_0_nsun2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PABPN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00827211
ST3GAL5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00347695
COX4I1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0052786
MTTP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00775531
TBXAS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00639942
GPER1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00725718
GSE163862_0_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Crohn's disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.639794
GSE151612_4_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
ANLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58428
P3H1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00709827
Nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE174701_4_v_3_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF99	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02328
STX11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00685449
MICALL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00574865
SEMA3F	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00489859
GSE138818_1_v_0_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K37989903	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20914
CACNA1G	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00586964
CSRP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00529849
GSE227698_2_v_4_g0s2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE128730_4_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100407_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.35773
CIT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00516016
PRTN3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00536832
BRD-K42016545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23607
GSE240896,GSE240899_2_v_4_ccnt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Ganglion	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.445
BRD-K21305828	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01759
CRCGN010_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2096
GSE242290_1_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.16445
PSTPIP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00613855
LRP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00511202
GSE154197_1_v_2_ints13_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K01534436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03196
COL8A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00631852
GSE156454_0_v_1_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K87669186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20605
KARPAS422	DepMap CRISPR Gene Dependency	1.0	5.02063
HEC116	DepMap CRISPR Gene Dependency	1.0	2.34913
BRD-K78972225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18273
GSE130081,GSE130082_4_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CYB5R2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00693917
GSE213588_8_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE216540_10_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
TTR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00691015
GSE129241_4_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-ensembl_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149903_4_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE131887_1_v_4_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
VIRMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2249
BRD-K07348252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57234
BRD-K03901181	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15686
BRD-K08723967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62432
GSE157282_0_v_3_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Diamine N-acetyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.091
BRD-K36055854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19829
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3442
CHRNA9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00702582
IDH3B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00676759
GSE129241_3_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7515
MAPK8IP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00587061
GSE210990,GSE211030_3_v_1_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199606_6_v_0_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MLXIPL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5081
CATSPER2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00534944
PMC6167382-41467_2018_6258_MOESM4_ESM.xlsx-TEAD-associated_GSC-Specific_UP-Nearest_Ensembl_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
DLD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00573087
TNFRSF9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00593974
BRD-K04635516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12123
PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-HIF1_HIF2_miRNA_targets_CoCl2-Unnamed_12_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K86978618	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23376
PMC9580020-tx2c00131_si_003.xlsx-Fig_5A_data-HSF1_KOVAC_same_dataset_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
RASGRP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00588245
PMC13000489-mmc1.xlsx-Table_S3-Table_S3_LC_related_genes_screened_by_MR_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
OFD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00751927
GSE138863_2_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAFF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00684525
GSE256181_2_v_3_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
NEFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46199
POMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7023
ZNF300	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00527471
BRD-K78983822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80682
CRCGN013_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.81618
KLHDC8B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00611534
3436_RACK1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.796179
SNAI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4314
SP140	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00539602
Cerebral hemisphere	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.21281
GSTO2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00531717
PALS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00496138
PRKAG2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00587519
BRD-K39597125	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40752
PYGL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0494
GMNN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00546736
GSE116810_5_v_4_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ATRAID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28415
INPP5D	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00603506
GSE242199_6_v_7_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K05205967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97395
BRD-K36544054	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0147
GSE213588_8_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MSMO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0090736
GSE213650_0_v_2_everolimus_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ADIPOR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00921028
BRD-K89476396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07184
GSE213588_10_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RBM6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00433388
BRD-K31024887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64983
CRCGN015_HEPG2_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.15517
SULT2B1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0106322
GSE88819_5_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PTPRJ	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00458016
SERPINF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00629023
GSE226249_5_v_4_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BTF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5642
SPATA19	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00964407
SIRPA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00560254
BRD-K18416855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85747
SLC4A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00570489
KCNA6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00619621
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
EPHB4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00538171
BRD-K65873444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11164
Colorectal cancer (diet interaction)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.530103
CRYZ	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00450614
BRD-K75814223	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84031
GSE207611,GSE207612_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RORA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00830187
GSE142684_0_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A68175400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05745
BRD-K39081386	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26877
PFKM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00540464
BRD-K12826618	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.34681
FMO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00534423
PTGFRN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00659767
GSE101537_4_v_2_neurog3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE178113,GSE178116_0_v_1_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10290283-biol-2022-0622-sm3.pdf-78-PURA_PURA	Rummagene Transcription Factor Associations 2026	1.0	null
KYSE30	DepMap CRISPR Gene Dependency	1.0	2.66209
PMC9537523-41467_2022_33364_MOESM7_ESM.xlsx-scores_wilcoxon_1_MONTH_ORG-EN1_n_EN1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K95943192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07771
PMC12254391-41598_2025_8960_MOESM5_ESM.xlsx-fig-Supplemental_Table_6_Differentially_Expressed_Genes_DEG_between_siRNA_DLX4_and_siRNA_control_n_3_RA_FLS_cell_lines_per_treatment_group_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A05956997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38955
GSE121866_0_v_3_six4_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K13225050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24848
PANC0504	DepMap CRISPR Gene Dependency	1.0	4.71471
IFI27	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00558194
FN3K	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00720319
LIG3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00558786
AP3D1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0063121
TMEM258	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29118
MUSK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00630025
BRD-K69471644	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34035
GSE127790_6_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Avian pallium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.445
NCLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00708
CA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00785127
TACR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00417836
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.6047
BRD-K49681465	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17025
PYGL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00331375
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
SW837	DepMap CRISPR Gene Dependency	1.0	2.21385
BRD-K61943321	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47392
GSE88819_3_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CD46	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00856007
GSE175787_5_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211128_9_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RPL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08194
GSE142232,GSE142234_0_v_2_gcgr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCM10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0079545
PMC8143797-elife-62857-fig3-data2.xlsx-DEgenes_SW872_TAZ-CAMTA1_vs_EV-Gene_CAMTA1	Rummagene Transcription Factor Associations 2026	1.0	null
BACE1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00966817
LIVF001-009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06667
NCIH510	DepMap CRISPR Gene Dependency	1.0	2.81305
BRD-K72591075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10229
POLR3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38093
GTEx AdiposeTissue 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	1.0	6.384
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.5715
DPH5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00630398
GSE226316_3_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
RHOBTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34562
TPP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00624768
Cerebral cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE175787_13_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC22A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00586221
PMC9509360-41419_2022_5262_MOESM6_ESM.xlsx-Fig_2D_MSC_targeted_RNF4-Up_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE224294_1_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE133683_3_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-OLIG2_UNIQUE_DYS_GENES-NEUN_TLE_vs_TL_log2FoldChange_1_padj_0_1_OLIG2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE124932_2_v_1_sarm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.6701
GSE192870_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PSMB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0063582
BRD-K62833556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84699
GSE134375_0_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE181959_3_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE226249_0_v_3_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CNOT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16371
BRD-K73227539	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54099
GSE126345_2_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE191105_2_v_4_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HUWE1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00504799
GSE176008_8_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7214
CRCGN014_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.7345
PSG2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00550573
chr19_46435226_C_T_b38	GTEx eQTL 2025	1.0	1.49141
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-4_E2F8-Gene_E2F8	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-HIF1_HIF2_miRNA_targets_CoCl2-Unnamed_5_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN017_MCF10A.WT.HP_24H:N18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.007
CRCGN015_HEPG2_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.02465
WAS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00594823
ARHGAP30	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00876265
GSE131649_6_v_10_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
TPRKB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00529457
FUT3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00560679
BRD-K71836501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.2128
ATIC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0080935
GSE239844_4_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE148262,GSE150691_1_v_0_hdlbp_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K38972344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5569
KLHL7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00660198
GSE210580_0_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K34701680	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92667
GSE104508_0_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ARCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59341
GSE146982_4_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K52124788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26702
RHCE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00541894
CAMK1G	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00728995
GSE193258,GSE193259_9_v_15_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN013_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43397
LGR5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00762439
GSE196104,GSE196106_2_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CGAS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00964109
BRD-K55623459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64537
SYT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00806194
BRD-K23164928	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20391
BRD-K84663394	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13544
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TCIRG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00610233
Esophagus - Mucosa	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.641552
BRD-A64153357	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61548
7538_RPS8_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.508183
BRD-K85615919	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7044
GRIN3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49091
RNPEP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00763525
GSE224599_0_v_1_tfcp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
ATF2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00497135
GSE175787_5_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GGPS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00471372
GSE184210_0_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE126345_11_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE89057_0_v_1_sox5_human	RummaGEO Gene Perturbation Signatures	1.0	null
PNMA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02746
DDX21	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00591788
HESX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00439752
CDC42SE1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00713796
NADK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00789193
chr19_46470724_G_A_b38	GTEx eQTL 2025	1.0	1.20594
BRD-K68087668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43632
GSE242290_1_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE213588_10_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K48207398	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04157
GSE165704_0_v_1_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PDE7A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00654686
NUP160	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00572218
GSE201309_1_v_0_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAP4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00720345
CRCGN017_MCF10A.WT.HP_24H:N10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.39555
IL18	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00606974
GSE216273,GSE216292_0_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MLNR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00828023
GSE119978,GSE180930_3_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.39687
BRD-K09304381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94
BRD-K37387086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23999
GSE228992_0_v_1_mafb_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62813
GSE164874_5_v_10_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE206516,GSE206518_0_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
YDJC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00582772
9453_TXNDC9_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.814596
BRD-K03141963	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09647
GSE140936,GSE140938_2_v_1_slfn11_human	RummaGEO Gene Perturbation Signatures	-1.0	null
OCIC4P	DepMap CRISPR Gene Dependency	1.0	2.56911
BRD-K66580188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34444
PMC10521995-pone.0291029.s023.xlsx-Het_vs_WT_Day23_FOSB_prox_genes-HUGO_Gene_Symbol_FOSB	Rummagene Transcription Factor Associations 2026	1.0	null
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.01082
Occipital lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.037
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.5403
ADRA2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00486104
CRCGN015_HEPG2_48H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.54597
BRD-K68424387	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18543
FASN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00401519
BRD-K97391170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44752
PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-HIF1_HIF2_miRNA_targets_DMOG-Unnamed_5_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_MCF10A.TP53.M_24H:P11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.371
BRD-K84178479	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45231
BRD-K28187112	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1651
GSE213588_10_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRAF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0108071
IL1RAP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0071974
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.5729
CLEC1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.006191
NEU2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00556598
TMEM216	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22884
GSE135350_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE146687_2_v_5_eribulin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-PAX6_UNIQUE_DYS_GENES-PAX6_TLE_vs_TL_log2FoldChange_1_padj_0_1_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
Adipose - Subcutaneous	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.682349
BRD-K57026098	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11016
BRD-K83902026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07459
KLF4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00632835
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-NEUN_UNIQUE_DYS_GENES-OLIG2_TLE_vs_TL_log2FoldChange_1_padj_0_1_OLIG2	Rummagene Transcription Factor Associations 2026	1.0	null
TGM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0045497
GSE102467_1_v_2_pazopanib_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.34633
BRD-K34858602	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0055
CHEK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00653069
AIRE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00503852
hydroxyamphetamine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06012
DTX3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00457697
GRIA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0110181
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	79.0468
BRD-K83872468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09483
BRD-K60531990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25085
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5089
GSE164874_5_v_4_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
WRAP53	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00665024
GSE116810_5_v_3_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE138841_0_v_1_trim6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9580020-tx2c00131_si_004.xlsx-Fig_5B_data-TABLE_S3_CORE_GENE_TARGETS_HSF1_KOVACS_ET_AL_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
IMPDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66052
CREB3L2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00684534
Prefrontal cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.301
GSE218727_2_v_1_zkscan3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135514_2_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K15126665	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8398
GSE157282_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1491
GSE193258,GSE193259_2_v_12_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RPS27A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07481
NME5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00524281
PMC2820592-NIHMS144142-supplement-8.xls-LMS_SAM_3-GENES_HIGHLY_EXPRESSED_IN_GROUP_III_LMS_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
TRAF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00677655
GSE231891_5_v_4_cdk8_human	RummaGEO Gene Perturbation Signatures	1.0	null
FUT4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00647955
TRAF3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0049095
GSE122990,GSE123061_0_v_1_urod_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K78397696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04504
BRD-K00509183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0183
CCNJL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20014
GSE127790_11_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K41684304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14252
11207_NON-TARGETING_NON-TARGETING	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.547841
TM9SF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82555
BMAL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00533049
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.1904
LRP12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00660721
ATP1B3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00871155
ABCB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00657817
GFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01274
BRD-K21662756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43778
GRIN2C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00651403
GMPR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00627554
GSE184892_6_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
CD24	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00732163
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-female_port-FOS_1_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
HHEX	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00465579
PPP2R2C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00478708
GSE165548_2_v_8_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF460	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4444
KRT23	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00536111
BRD-K85449516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04585
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.35773
GSE156923_2_v_3_rbmx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1245
BRD-K83336425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5307
GSE176008_0_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE165308_1_v_0_gfi1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4686057-pone.0145107.s001.xlsx-CAA-C-Unnamed_0_TSHZ1	Rummagene Transcription Factor Associations 2026	1.0	null
HOXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57247
GSE214931_2_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Bronchoalveolar system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
496100455_FWM_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.54981
CDC37	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00705911
SLCO4A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00568139
RB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04695
GSE234340_10_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CYB5R3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00540281
PMC7773934-Table_1.XLSX-Table_S2-Supplementary_Table_2_TBX22_co-expressed_genes_detailed_results_TBX22	Rummagene Transcription Factor Associations 2026	1.0	null
RASSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04649
496100396_HIP_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.29368
SFMBT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.007021
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0464
SCN10A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00715775
MYBL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3073
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.08104
ERCC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3278
MBNL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00476437
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-PAX6_UNIQUE_DYS_GENES-NEUN_TLE_vs_TL_log2FoldChange_1_padj_0_1_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
CKMT2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00600484
BRD-K80176886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21729
RPS6KC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00543738
GSE139966_4_v_0_figla_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE139016_3_v_2_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_7_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K98441254	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76262
SRSF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7989
GSE240258_0_v_1_prmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.8292
MZB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00943471
CDKL4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00492869
BRD-K21588993	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23457
GSE168807_0_v_8_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K67399222	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58325
Zic3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.8505
RAB8B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00840383
GSE180185_7_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K75904236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.74055
debrisoquin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63749
BRD-K28952606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07021
PMC8635809-Table_2.xls-LPS-downregulated-Unnamed_4_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE242199_9_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148514_0_v_1_rreb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE239844_6_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE165548_2_v_13_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ITGB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00678281
BRD-K11905754	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84571
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.40805
ISM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00517759
DGKI	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.006159
BRD-K96258717	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08348
CADM3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00565384
3537_GRINA_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.508042
ILF3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00531932
GSE242199_6_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
HNMT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00498567
BRD-K67689282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01425
GSE245270_1_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE94849_7_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NICN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00666086
GSE192870_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158834_7_v_13_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00803782
BRD-K14756138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05036
MGST1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00503456
GSE130437_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K08730634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27634
SLC6A12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00786817
GSE171572_3_v_4_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K60937893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03289
VEGFA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00689996
GSE135514_8_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CCN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31042
SW620	DepMap CRISPR Gene Dependency	1.0	2.93158
176_AFG3L2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.597636
MED17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17638
ZNRD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00569128
SCN9A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00694364
GSE119498_0_v_7_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DEFB4A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00645071
DHRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45432
GSE120781,GSE174528_4_v_1_ctcf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7232
Skin - Not Sun Exposed (Suprapubic)	GTEx Tissue Gene Expression Profiles 2023	1.0	3.35344
NOP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15218
BRD-K97729706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44743
GSE239844_1_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE178532_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K04275703	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38101
GSE171352_2_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K79678951	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49015
CNOT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39208
BRD-K06029218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31032
BHLHE40	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00636931
496100507_FWM_dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.09838
BRD-K29083370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34933
GSE184892_4_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE234647_1_v_3_regorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Epithalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.267
DTHD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00526341
ZNF710	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19313
GNAI2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00511617
GSE162590_1_v_0_gsx2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SACM1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48794
SLC16A7+ cell_Lung_Human	CellMarker Gene-Cell Type Associations	1.0	null
PMC9634663-DataSheet10.xlsx-K562-MYC-AID_RNA-Seq_1326_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
Stomach	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.637092
BRD-K04712840	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00094
GSE242290_1_v_2_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
DACT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02332
GSE233679_6_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LMAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04325
GSE216273,GSE216292_0_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HAPLN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00530104
GSE146687_2_v_0_eribulin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NT5E	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0089639
GSE216273,GSE216292_0_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.52644
SLC39A14	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00917152
SUMO activating enzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.072
GSE195743_1_v_4_lhx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Night sleep phenotypes	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.552288
LRRC4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00749885
BRD-K20368781	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10606
CRCGN015_HEPG2_48H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.31084
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_3_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K95798946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11799
LTB4R2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00824361
BRD-K46334103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13625
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.4255
LIVF001-027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95203
GSE231891_5_v_0_cdk8_human	RummaGEO Gene Perturbation Signatures	1.0	null
Temporal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K12696543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06618
GSE174701_1_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
SETD1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00561164
PSMA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44909
BRD-K16118844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54763
CRCGN015_MCF10A.TP53.M_24H:O24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3161
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.225
Pierpont syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.481
BRD-K28472865	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07818
GSE193258,GSE193259_9_v_12_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE176008_0_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cervix - Ectocervix	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.68334
NKX3-1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00740478
OXT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00466313
BRD-A34826857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51335
CYB561D1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0139187
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE212312_1_v_3_fbxw7_human	RummaGEO Gene Perturbation Signatures	1.0	null
PHTF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00639369
GSE126345_0_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE232564,GSE232566_0_v_2_nsd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE193258,GSE193259_9_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9305137-PATH-256-297-s005.xlsx-CIC_associated_DE_genes_IDH1-R-Unnamed_1_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
TICAM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00411649
GSE184210_0_v_1_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SNX16	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00587695
BRD-K23825243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07986
GSE180185_7_v_5_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GNA12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00486885
Parametrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.556
CRCGN015_HEPG2_48H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.60454
IL33	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00972774
BRD-K08828851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06058
PMC7220941-41598_2020_64431_MOESM2_ESM.xlsx-WS2_2019_Affy_IDs_SignalsQN-Unnamed_2_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
APOB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00604481
SOAT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00868696
BRD-K25842662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10797
8765_TCEA2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.609872
NZOV9	DepMap CRISPR Gene Dependency	1.0	6.8877
CELA2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00689632
BRD-K66954388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14381
ENTPD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00914746
GSE138789_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PITX3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00565839
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7005
ARHGAP23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69237
RGS10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00785968
QPCT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00525288
GSE174701_5_v_8_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE127790_5_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE218819_3_v_4_kdm5b_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE226249_2_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE118077_4_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K62624148	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08945
Ikzf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.0803
GSE211425_1_v_0_mettl3_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100532_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.01423
GSE261563_3_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VSTM4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00567532
GSE216540_1_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE164874_5_v_11_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4060771-170289.f1.pdf-391-MEIS1_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
ARL17A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0137073
CRCGN017_MCF10A.WT.HP_24H:P08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5081
TRMT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22304
GSE219195_1_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
LRIG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00880508
SUMO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00544108
GSE256181_1_v_0_etv2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE126345_0_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NELFE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00552233
GSE242083,GSE242098_3_v_5_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ENTPD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0113076
BRD-K91039552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38073
FCRL5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00575218
LTN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00482067
GSE214931_1_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
MSGN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57435
SLC39A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07508
GSE239688_4_v_0_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K67702605	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10985
GSE171401_1_v_2_adnp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE102505_5_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PRDM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00775
GSE126345_7_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE229671,GSE229673_2_v_1_yrdc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TTC30B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58839
NFATC4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00388977
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.1586
SPC25	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00612098
GSE149901_3_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
537_ARPC3_P1	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.535329
VMRCLCD	DepMap CRISPR Gene Dependency	1.0	2.43081
BRD-K56889360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98348
CRCGN015_MCF10A.TP53.M_24H:F22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2503
CHD9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00600317
GSE206516,GSE206518_5_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
ARNT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2569
BRD-K56536241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18467
GSE216273,GSE216292_14_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TTC7A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0062318
GSE195743_3_v_2_lhx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TUBA1C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00791392
GSE70935_3_v_4_cyfip1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TCN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00747549
EP400	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20772
GSE163297_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE239844_6_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.27127
GSE232558_0_v_1_fbxl12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K40695780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.435
GSE120612_4_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CCL11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00853811
CHP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00398677
GSE149621_2_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ALDH1A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00888941
GSE147056_4_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
WNK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00588184
COBL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00474443
VPS13B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00747589
NTERA2CLD1	DepMap CRISPR Gene Dependency	1.0	2.71028
GAD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00530232
GSE210101,GSE210114_0_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE181513_2_v_1_usp7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Chorionic plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.535
GSE77108_0_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE226249_2_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE150072,GSE169209_6_v_9_qser1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CCC5	DepMap CRISPR Gene Dependency	1.0	3.6368
GSE233679_12_v_2_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IGF2BP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00450088
BRD-K16641781	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01243
Central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.63606
CLC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00674063
HSPA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32775
CRCGN012_HEPG2_24H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06084
CYP51A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00548604
AGTRAP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0058669
CCR7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00484199
CHRM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00688948
GSE102467_1_v_0_pazopanib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TPM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0058553
BRD-K82935855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38963
RFX5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00553063
GSE175787_11_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K74663731	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54013
GSE219195_4_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE218580_1_v_0_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A71590475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.431
CD36	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00548758
BRD-K53771043	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20941
BRD-A77181042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70464
BRD-K75094875	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74344
BRD-K38209615	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45277
GSE214931_3_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GABRA5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00541829
SBNO2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00441791
MX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00793843
GSE218060_1_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE242290_1_v_8_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
CCND1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00930235
butyrylcholine-cl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23663
CARMIL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00520181
GSE150072,GSE169209_6_v_11_qser1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HTR2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00521041
RNPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3886
BRD-K68202226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57055
GSE135514_2_v_6_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE123861_1_v_0_sin3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CYP4F2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00590374
GSE67266_7_v_3_etoposide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1773
BRD-K87865520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09331
Limbic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CXCL3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00853604
PMC7687904-41598_2020_75770_MOESM1_ESM.xlsx-SP2-Gene_SP2	Rummagene Transcription Factor Associations 2026	1.0	null
PIGP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01623
GJD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00955629
GSE139016_0_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
HSD3B2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0062872
CENPI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50708
CDKN1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00719495
KCNJ5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00586148
BRD-K35943892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22821
GSE111660_1_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ATG5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00636561
Diencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.459
PMC10181932-41588_2023_1366_MOESM4_ESM.xlsx-Supplementary_Table_2-Supplementary_Table_2_Additional_information_for_all_SOX9-dependent_genes_SOX9	Rummagene Transcription Factor Associations 2026	1.0	null
GSE87615_2_v_3_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SULT1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91906
PAPOLB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06059
CNR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0116369
GSE200673,GSE200691_1_v_4_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE116810_5_v_1_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TEAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6494
tylosin-tartrate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12466
GSE119498_2_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BPIFA3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00618943
GSE126345_9_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8242083-41467_2021_24064_MOESM4_ESM.txt--HSF1_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_10_CCF-Affected_Genes_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
HEY1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7172
BRD-K47170544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04377
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.3947
CPVL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00567003
chr19_46471142_C_G_b38	GTEx eQTL 2025	1.0	3.39073
BRD-K24529791	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06703
CDC14A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00585427
GSE261563_9_v_4_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE88819_6_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TGFB1I1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00906654
GSE210101,GSE210114_6_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
KCNMA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00625298
RGS5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.007187
BRD-K84936524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07069
EHHADH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0123877
BRD-K27287379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02549
GSE87615_1_v_3_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PGRMC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65435
EHMT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00497429
RFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19114
KDM5B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00384471
GSE70935_2_v_4_cyfip1_human	RummaGEO Gene Perturbation Signatures	1.0	null
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15546
ING4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00658025
TLR6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00487047
IL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00762181
SMC1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0127074
GSE220600_1_v_2_clpp_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HRH3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00533523
INPP4A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00712093
BRD-K35848924	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03565
BRD-K15508005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57931
PMC10713402-aging-15-205220-s005.docx-0-RBAK_RBAK	Rummagene Transcription Factor Associations 2026	1.0	null
GSE144231_6_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RFX7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3142
PFKFB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0073189
RFX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9561
PMC8530322-pone.0258316.s002.xlsx-GG_776_TH17-AA_776_TH17-Symbol_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
YBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0694
GSE200673,GSE200691_1_v_3_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Differentially_expressed_genes_identified_in_bulk_RNA-seq_of_FOXO1-_-_vs_FOXO1_hMSCs_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
RAF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00614375
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.5443
STK16	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00539146
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.47597
ACKR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00601802
GSE173262_2_v_5_ash1l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE242290_3_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
EIF2AK4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00598336
VDAC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00678693
BRD-K07820537	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25292
GSE201309_4_v_7_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_1_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
MAGOH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85112
HAX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00635643
BRD-K94915822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0416
SYS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42172
TLR9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0090277
BRD-K90965240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21082
Gli1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.3975
GSE126345_4_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE131887_1_v_0_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE242199_9_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
H413	DepMap CRISPR Gene Dependency	1.0	2.60517
GSE149903_6_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GDAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13867
BRD-K27578003	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03152
CRCGN015_HEPG2_48H:M23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03195
MAP6D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15486
HPAEC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.508
CHRNA4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00960335
ZWINT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00376091
CRP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00962366
PRUNE1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00548621
PMC8202205-NIHMS1706275-supplement-Table_S3.xlsx-Day_2_GATA6-dependent_genes-GATA6-dependent_mRNA_expression_Day_2_Mesendoderm_FDR_0_05_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GRK4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00651093
GSE181517_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A_48H:B11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.16597
CSNK1D	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00580095
PCF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13774
BRD-K18298066	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11743
BRD-K44624253	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31997
BRD-K50092006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29175
SLC13A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00821348
BRD-K49995660	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93119
RASSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49953
PHF5A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00620541
BRD-K49992772	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19059
JSRP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00630573
LSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04334
Cervix - Endocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	1.92091
SFTPD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00774481
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5639
DNAJC16	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.010395
GSE196259_2_v_3_gcm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FAM89A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00593016
BRD-K31883758	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17018
IGHMBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23985
POLR3H	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00627054
FTSJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27405
SLC25A34	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00646609
CD8A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0071653
GSE234340_4_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE175787_11_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
MOLM14	DepMap CRISPR Gene Dependency	1.0	2.4628
GSE207582_4_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PPP1CA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00707496
GSE194396,GSE194429_1_v_0_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2908
GSE242199_9_v_7_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
EIF5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21474
GSE144231_2_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE226249_2_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.WT.HP_24H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.04966
B4GALNT3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00569952
PIK3CD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00487564
BRD-K18932682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18933
CRCGN012_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3846
Diffuse astrocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.111
TNFRSF1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00356895
GSE171572_5_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE65617_2_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210682_0_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1937
HSD17B4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0083519
PMC8481886-Table_1.xlsx-A_subsets-iMSC_fetal_MSC_UC_MSC_bone_marrow_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
PAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06082
TSPAN13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00754746
BRD-K07798964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30065
KPNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42233
GSE195568_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ROS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00589181
PMC9530161-41419_2022_5296_MOESM2_ESM.xlsx-Tab6_KDM5C-KD-up_genes-Table_6_Up_regulated_genes_in_KDM5C-KD_KDM5C-KD1_Control_overlap_KDM5C-KD2_Control_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-NEUN_UNIQUE_DYS_GENES-PAX6_TLE_vs_TL_log2FoldChange_1_padj_0_1_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
BHLHE41	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.855
PMC6070530-41398_2018_200_MOESM3_ESM.xlsx-regional_cluster_PFC-MSC-age-bin_9_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
CD207	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0060097
GSE182179_2_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE48812_8_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE135514_2_v_9_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE193258,GSE193259_9_v_13_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN014_HEPG2_3H:A11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.24526
LYPD6B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00925417
CRCGN016_MCF10A.TP53.M_24H:F14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.69677
BRD-K46726368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42982
RPS6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00599862
GSE144453,GSE144454_1_v_0_tfdp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K49328983	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44007
GRPEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6885
MEFV	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00511021
PLA2R1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00627012
CRCGN017_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.90755
Cerebral lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SPIB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00654125
BRD-A00522887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24531
GSE160304,GSE163392_7_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119978,GSE180930_6_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K08205503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25305
CSF2RB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00756407
PLTP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00676229
GSE111385_0_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CHRNE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00813256
SULT2A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00637339
PMC7687904-41598_2020_75770_MOESM1_ESM.xlsx-SP2-ENSGID_SP2	Rummagene Transcription Factor Associations 2026	1.0	null
DNASE1L3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00761483
APBB1IP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00590876
BRD-K08009212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04316
ADPGK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00612366
BATF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00599327
MPZL3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00429989
GSE210101,GSE210114_7_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
RB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0058083
KCTD16	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00525608
GSE174701_5_v_3_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE196540,GSE196542_2_v_0_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CARD8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00862959
ALOX5AP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00696949
BRD-K48221699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27341
AMY2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00596495
WNT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00742259
GSE119498_6_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K25013674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19556
CTSC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00597628
431_AQR_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.812005
STAT3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00433648
FHL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00818247
TRAF4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0048665
GSE128730_7_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K38190084	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02916
ARHGAP25	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00539212
MZT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83801
Telencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CRCGN014_HEPG2_24H:H18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15313
PCTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07388
FKBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46059
GSE189789_0_v_1_oridonin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.3299
GSE239844_11_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE248887_0_v_1_dkk1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE242367_1_v_0_dpp9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE128730_3_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10824666-43018_2023_699_MOESM2_ESM.xls-Suppl_Table_S4-AM-1882_AUC_vs_Gene_Expression_PRISM_Breast_and_Ovarian_Cancer_Cell_lines_n_58_PRDM6	Rummagene Transcription Factor Associations 2026	1.0	null
H2AC12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00629041
BRD-K40367360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02063
LNPEP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00474094
GSE162892_3_v_1_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE239844_7_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10244410-41467_2023_39054_MOESM5_ESM.xlsx-PIE-LIN28B-GeneSymbol_LIN28B	Rummagene Transcription Factor Associations 2026	1.0	null
pantothenic-acid	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15392
GSE174498,GSE174500_3_v_4_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A95683194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44755
BRD-K54141118	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75389
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.5285
VRK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0056999
BRD-K47511177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60521
Oligodendroglioma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.892
NCBP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00809327
TMEM98	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00975181
6850_PSMB2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.64498
GSE239844_6_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE195559_2_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PLAGL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00757473
CRCGN016_MCF10A.TP53.M_24H:O23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.45092
BPH1	DepMap CRISPR Gene Dependency	1.0	2.07076
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
OPRK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0113562
ZC3H12C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00643169
BRD-K81725246	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43584
SLC52A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0126297
GSE174701_1_v_7_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GRIK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00566093
Pituitary	GTEx Tissue Gene Expression Profiles 2023	1.0	2.17065
BRD-K02809100	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52164
BRD-K83846772	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37425
IVD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00609058
GSE153836_11_v_2_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
KLHDC7B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00567995
NADSYN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00407863
GSE216273,GSE216292_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTSH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00382354
GSE176008_7_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A59449038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2248
GAD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00542844
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9528
RFNG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15157
GSE233679_12_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K63892351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06343
496100322_FWM_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.26583
CRCGN016_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.48878
GSE216043_7_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
JVE015	DepMap CRISPR Gene Dependency	1.0	7.88319
ZSCAN29	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.128
ZNF460	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	103.652
GSE175787_13_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RIGI	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00731738
GSE218727_2_v_3_zkscan3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE138468_3_v_6_dyrk1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
YME1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10654
CRCGN011_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.2932
TENM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19187
GSE169263_1_v_0_armc5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE207514,GSE207515_0_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K45508763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09357
LGALS16	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00547367
NR1I3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00635895
GSE197686,GSE197688_2_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE245407,GSE245412_0_v_1_smurf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K10513366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34129
CCL17	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00601047
BRD-K59708864	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05613
RPS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12909
COL18A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00749333
NDUFA13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00818202
SLC25A13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00504288
FES	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0055094
PYGO2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00744569
HLA-DQA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0080327
GSE239844_8_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K93335719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83622
CRCGN015_HEPG2_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.20801
HS294T	DepMap CRISPR Gene Dependency	1.0	2.75781
GSE92457_7_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7870953-41540_2021_169_MOESM9_ESM.xlsx-RREB1_targets-target_gene_RREB1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K79730625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32538
NEDD9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00484834
CENPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08846
SEC63	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32661
EBV-LCL cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.258
BRD-K14181473	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50671
GSE112761,GSE112767_1_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NDUFC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00703497
ASMT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00574995
BRD-K60080002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50465
CRCGN016_MCF10A.TP53.M_24H:H16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.20636
DEPDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12536
NMB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00761067
NFATC2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42911
JHH5	DepMap CRISPR Gene Dependency	1.0	8.59589
GSE184892_7_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
TNFRSF10B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00658947
CRCGN015_HEPG2_48H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.32605
GSE195559_8_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE139975_3_v_0_rnf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IL11RA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00554923
SH4	DepMap CRISPR Gene Dependency	1.0	3.53382
FBXL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28444
OMM25	DepMap CRISPR Gene Dependency	1.0	3.06293
SLC12A4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00755929
BRD-K54024474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.3835
FOXP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79554
GSE211262,GSE211263_2_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CASKI	DepMap CRISPR Gene Dependency	1.0	2.41412
CRCGN015_MCF10A.WT.HP_24H:E11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.27584
BRD-K70819166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76422
GSE242199_9_v_11_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TOP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00409951
GSE162892_3_v_5_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE175787_4_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TSSK1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00706421
BRD-K83301268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35659
GSE200673,GSE200691_1_v_5_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.1603
COQ8B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00594344
KLF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43342
GSE128240_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A.WT.HP_24H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03915
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.07129
SSC4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0551
ICOS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00508685
COX6A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66834
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-19q13_43_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
CDK18	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00649827
GSE140936,GSE140938_0_v_1_slfn11_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213650_3_v_2_everolimus_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNU840	DepMap CRISPR Gene Dependency	1.0	2.77859
RAB3IP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00619545
BRD-K53559383	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44503
KCNE2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00534082
BRD-K90702747	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45763
GSE212299_2_v_1_abi3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K48714854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25176
GSE120216_3_v_0_cbfb_human	RummaGEO Gene Perturbation Signatures	1.0	null
LPAR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00589463
PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-HIF1_HIF2_miRNA_targets_CoCl2-Unnamed_1_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7959
CRCGN015_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.96446
BRD-K88448214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4869
GEMIN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16617
GSE155800_1_v_0_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE111660_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE77108_3_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
CD27	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00609765
GSE146982_4_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
NOMO1	DepMap CRISPR Gene Dependency	1.0	4.673
GSE131649_6_v_3_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE201270,GSE201272_0_v_3_mybl2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
ractopamine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.68401
BRD-K37433647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44161
TNFSF11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00557768
GSE210580_0_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE116810_2_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE210580_0_v_12_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FGFR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00512186
UQCRC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00722914
PTPRK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00440743
BRD-K12336887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02789
GSE175787_4_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ABCD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0063084
GRIK5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00572023
SLCO1C1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0049522
BRD-K12469242	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93517
GSE158834_7_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE65617_5_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PRKRA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00726365
GSE113817_2_v_1_bach1_human	RummaGEO Gene Perturbation Signatures	1.0	null
S100A6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00680292
LIPT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0080777
CRCGN016_MCF10A.TP53.M_24H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2088
GSE157383_0_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PPP2CA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07474
TMIGD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00746712
GSTA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00642372
GPM6B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00582561
Papillary thyroid cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.506
NPY2R	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00508405
BRD-K07486034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00534
PMC12254391-41598_2025_8960_MOESM5_ESM.xlsx-Suppl_Table_6_DEG-Supplemental_Table_6_Differentially_Expressed_Genes_DEG_between_siRNA_DLX4_and_siRNA_control_n_3_RA_FLS_cell_lines_per_treatment_group_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
TRAF2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.010003
ICAM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00358483
BRD-K41809155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19898
CDPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67608
BRD-K40509138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97381
LIVF001-015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17927
BTNL10P	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00610595
GSE181517_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07557
SLC1A4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00426378
TBC1D20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04308
GSE128730_4_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ILKAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74303
ARHGAP31	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00538775
MAP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00463327
GSE142684_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE126345_2_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IRF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65784
CCDC160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03126
GSE195663_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24036
GSE126345_9_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LDHA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00384772
GSE134375_6_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DNAJB9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00760211
BRD-K37564297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28205
USF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8884
SHMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07742
NCF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00465972
GSE129293_0_v_1_chd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE111660_1_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A99644411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.3809
BRD-K21784579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57468
TFE3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9118
BRD-K18629365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15778
GSE224969,GSE224971_0_v_1_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SPATS2L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00689841
GSE148657_2_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182180_1_v_2_secretin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PTGER3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0110614
PMC9859043-elife-78421-supp9.xlsx-LHX8_P-Gene_symbol_LHX8	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF513	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00546283
BRD-K56661847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05856
9482_UBA52_P1	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.638822
ISTMEL1	DepMap CRISPR Gene Dependency	1.0	5.01428
BIN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00824687
GSE242367_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K38907993	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18667
SLC19A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00816492
IRAK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00733239
PMC7220941-41598_2020_64431_MOESM2_ESM.xlsx-WS1_2019_Affy_IDs_RA-STvsOA-ST-Unnamed_2_PAX3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K94011376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62129
Anaplastic oligodendroglioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.379
GSE234340_3_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K62547690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32543
GSE120612_4_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE151083_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NOZ	DepMap CRISPR Gene Dependency	1.0	2.20712
GSE139911_0_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.1992
GSE221077_1_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE131887_5_v_3_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE193258,GSE193259_9_v_0_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K32124229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00612
TRIP13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60481
GSE128730_0_v_1_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K54100265	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04493
BRD-K43341506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01667
OVMIU	DepMap CRISPR Gene Dependency	1.0	4.67981
GSE240386,GSE242143_1_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SW579	DepMap CRISPR Gene Dependency	1.0	2.99942
BRD-K50075939	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31799
HCT15	DepMap CRISPR Gene Dependency	1.0	2.35553
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.3955
CREB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62572
Gli2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.5273
SNUPN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00687879
BRD-K81544427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10863
GSE172494_3_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00554074
PROM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00878503
TAF5L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00611736
RNASE2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00599265
GSE132948,GSE132949_2_v_5_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE176008_4_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SIGLEC6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00533132
LAMTOR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00639741
RPS6KA4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00672696
ATP5PO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67205
USF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1163
GSE213588_10_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A10417568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53893
Lung	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.577961
GSE239844_1_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K92059157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54045
GSE239844_6_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BDKRB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00762331
NUCKS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00431307
BRD-K11423211	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31923
NR4A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00724385
CRCGN014_HEPG2_3H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1566
SHISAL2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00990492
GSE239844_11_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE239844_8_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE134375_6_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RUFY4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0051682
ETNK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00685532
LCK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00874598
BRD-K61370861	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22165
EXOC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04491
MYO3B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00655414
Hypothalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.459
BRD-K39543844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49339
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_2_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
WARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19237
IGF2BP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00341535
QRICH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0123473
GSE196540,GSE196542_2_v_3_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0816
P3H3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00634997
SUCLG2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00654728
GSE148200_3_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE118077_1_v_8_sprr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE229671,GSE229673_3_v_1_yrdc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC3610249-1471-2164-14-184-S4.xls-miR-331-3p_targets-NR2E3_NR2E3	Rummagene Transcription Factor Associations 2026	1.0	null
NLGN4X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81236
TMEM33	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00646181
JMJD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00261
IDO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00533356
GSE218580_1_v_5_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CAV3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00418967
Artery - Aorta	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.674751
GSE119498_0_v_10_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CIITA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00526624
GSE210580_4_v_6_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE240896,GSE240899_10_v_4_ccnt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PCCA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00512552
GSE77108_5_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.47868
ECE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66659
GRK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00557483
6017_P2RY1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.644789
PMC10521995-pone.0291029.s023.xlsx-Hom_vs_WT_Day23_FOSB_prox_genes-HUGO_Gene_Symbol_FOSB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE130676_0_v_2_suds3_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K59970200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30652
GSE197555_0_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TAF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00547939
GSE180525,GSE180528_1_v_0_tbx3_human	RummaGEO Gene Perturbation Signatures	1.0	null
TRIM69	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00707615
ADH5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00249904
SEC61G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31311
DUSP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00490092
CRCGN008_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1876
PMC5798892-41421_2017_3_MOESM8_ESM.xlsx-down-regulated-Supplementary_Table_S3_Up-_and_downregulated_genes_in_ATF6-_-_hMSCs_compared_to_ATF6_hMSCs_late_passage_ATF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE164874_5_v_9_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
DDX52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2864
NCIH1993	DepMap CRISPR Gene Dependency	1.0	3.42093
CRCGN015_MCF10A.TP53.M_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5852
PMC6744561-41467_2019_12125_MOESM8_ESM.xlsx-SEs_in_MCF10DCIS-TCF7_cells-Enhancer_to_gene_TCF7	Rummagene Transcription Factor Associations 2026	1.0	null
GSE129811_5_v_0_niacin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE213228_4_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE245270_2_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K32195266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25121
Pineal gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.267
DDC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00448544
BRD-K15259924	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69976
BRD-K55311609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.08911
ITGA2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00566079
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5414
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_downreg-human_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
SGF29	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0078331
BRD-K20288742	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03973
TXNRD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00514701
CAMA1	DepMap CRISPR Gene Dependency	1.0	2.25957
GSE93309_5_v_3_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K61407677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97117
PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Ensembl_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
OLFML2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54889
LRRIQ3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00538616
BRD-K49903196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26705
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7351
CLTC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36805
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSS	DepMap CRISPR Gene Dependency	1.0	2.29135
BTLA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00684151
Frontal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.301
PMC7334247-12031_2020_1490_MOESM2_ESM.xls-THAP1_F81L_vs_wt-Gene_Symbol_THAP1	Rummagene Transcription Factor Associations 2026	1.0	null
CDK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31793
GSE242199_9_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE215351,GSE215794_2_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BCL2L11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00701171
SOD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00456169
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE226285_3_v_1_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
CHRNA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00481181
JAK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00827631
GSE217363_2_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE220629_0_v_1_foxp3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DYNC1LI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0322
HTR1E	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00764267
PSG3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00656142
Brain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HOMER2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00410752
GSE218580_1_v_4_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_ZSCAN4-Unnamed_3_ZSCAN4	Rummagene Transcription Factor Associations 2026	1.0	null
COQ10A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63065
GNPTAB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00677739
BRD-K88150784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81908
SLC12A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0118961
BRD-K14695590	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79448
GSE203017_0_v_1_irs2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE229914_2_v_3_keap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.692
ZNF669	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.96
GSE210101,GSE210114_5_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
UNCX	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00669898
GSE206516,GSE206518_6_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IL18R1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0064372
BRD-K74144927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0463
GABPB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00724759
GSE233679_6_v_2_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE198380_0_v_1_phgdh_human	RummaGEO Gene Perturbation Signatures	1.0	null
PLD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00582439
GSE173262_2_v_0_ash1l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SNCA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00714056
PLSCR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00531049
GSE206784_3_v_4_ninl_human	RummaGEO Gene Perturbation Signatures	1.0	null
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.386
BRD-K75143842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1028
GSE128333_3_v_0_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K25917968	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08135
PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-HIF1_HIF2_miRNA_targets_CoCl2-Unnamed_16_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9305137-PATH-256-297-s005.xlsx-CIC_associated_DE_genes_IDH1-W-Unnamed_1_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
ACTL6A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00464546
CRCGN015_HEPG2_48H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.38052
LILRA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00576311
QPRT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00594054
TM6SF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00566384
GSE216273,GSE216292_0_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K44086628	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05252
Bronchus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE183041_1_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TGFB3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00446979
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-female_port-FOS_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
LB1047RCC	DepMap CRISPR Gene Dependency	1.0	3.25973
CRCGN015_MCF10A_48H:F02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2794
CFPAC1	DepMap CRISPR Gene Dependency	1.0	4.63159
DHCR7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00413861
BRD-K52157065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42191
BRD-K17606413	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2613
DLG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66745
GSE127790_9_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF_D1_vs_D10-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
RGS14	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00602026
GSE234043_3_v_1_abcb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE102505_1_v_2_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE245270_2_v_5_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE216043_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CYP2C8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00428034
Whole Blood	GTEx Tissue Gene Expression Profiles 2023	1.0	1.81718
SLC26A9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00469219
LIMA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00903508
PSMB8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00410453
RAMP3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00961439
CRCGN015_HEPG2_48H:L02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.72436
PNOC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0066083
PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Unnamed_1_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K20624967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80739
GSE213588_8_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE153836_11_v_9_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
KEL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00648718
BRD-K02371763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50806
BRD-K01367715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04974
BRD-K32535831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01137
RCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70057
PELO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78647
GSE158834_12_v_13_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE164874_5_v_3_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
USP28	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00628207
NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.8119
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.5106
BRD-K91490997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03021
BRD-K36716113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02679
GSE182854_2_v_0_sirt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ACSL6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00724471
TRIP10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00470401
BRD-K54484272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21861
CRCGN015_MCF10A.TP53.M_24H:L09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.37875
KNS42	DepMap CRISPR Gene Dependency	1.0	2.02135
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.79585
UBE2D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34941
BRD-K79064458	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01853
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.3261
MYLIP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00971507
KANK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20769
CYP2A6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00590508
BRD-K75772626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01825
EIF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38959
B3GALNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12173
GSE158182_5_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NOXO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00628345
Villous cytotrophoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.523