association	dataset	threshold value	standardized value
TBX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13058
SLC25A36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25371
HIPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32087
GSE173873_1_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PAIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48932
GSE76425_0_v_12_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE184133,GSE184137_2_v_5_esrrb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ACTR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27473
GSE138019_1_v_5_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SEC63	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94623
POU6F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64516
GSE189683_1_v_2_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE181959_3_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE120612_4_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SLC2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2517
GSE174701_1_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
TMEM65	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86836
GSE198165,GSE198166_7_v_4_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE180185_7_v_10_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DBT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73106
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.52171
GSE205316,GSE205317_2_v_3_nrip1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COL8A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09996
SNCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25335
496100322_FWM_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.22435
YIPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2497
GSE214382,GSE214383_4_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE226249_5_v_3_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
C1QTNF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76628
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.8117
VTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57363
GSE245270_2_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TTLL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64705
MSH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20958
GSE136622_6_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0844
TMEM184C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92719
GSE203267_0_v_1_alkbh5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MED13L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34643
BCL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49914
NR4A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77239
PRKAA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64492
C2CD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10494
PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT38_Protein_cis-instrument_MR-Unnamed_2_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
RHOBTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72479
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_id_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE151782_6_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SERINC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52545
GSE151829,GSE151831_1_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ATP5F1E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60978
GSE149880_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE219195_0_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
MED12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1988
PDXP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2125
POR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73268
chr19_46475745_G_C_b38	GTEx eQTL 2025	1.0	1.57433
ATP11C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10424
SPTY2D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78526
CRACR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02303
L3MBTL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72269
ZMYND11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36324
PMC10111863-supp_gad.350269.122_Supplemental_Paun350269_FileS3.xlsx-A_ASCL1-regulated_DGE-geneID_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE188870,GSE188871_1_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RRN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88206
GSE125153_1_v_0_bcl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE71529,GSE71558_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MAPK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63748
LRRC34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56517
GSE157555,GSE157556_3_v_7_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9882185-media-4.xlsx-Neuron_KD-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MKX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03541
Exocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.81
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.89787
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.47606
GSE62292,GSE62295_2_v_0_col4a3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.02768
DYNC2I1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55305
PGM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84443
MAPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90675
LAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5308
FGF22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71699
GSE188869,GSE188871_2_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE204832_0_v_1_imiquimod_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RNF185	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85169
GSE215351,GSE215794_1_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE113106_2_v_4_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PPP1R18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66802
ZSCAN29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58472
XYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27067
GSE131887_1_v_0_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE149880_0_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
DFFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7804
GSE234340_4_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
chr19_46476834_T_C_b38	GTEx eQTL 2025	1.0	1.25033
GSE156115_2_v_1_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE144231_2_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55642
HERC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5783
GSE216043_10_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
R3HCC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5361
STAT5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31086
VPS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04699
ZNF93	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	112.792
GSE65617_5_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LEFTY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65872
CAMTA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62484
RRBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98689
GSE240645_1_v_0_u90926_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4860404-Table1.XLSX-MR_unique-Table_S1-7_DEG_unique_in_mouse_and_rat_SCI_at_1_dpi_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
SETDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09833
GSE174701_5_v_8_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE92457_7_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZSCAN31	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3824
GSE189653,GSE203344_5_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158834_12_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
GSE125219,GSE125221_3_v_8_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
TYKNU	DepMap CRISPR Gene Dependency	1.0	6.087
KLHL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54109
NICN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44003
ACY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57611
PIK3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67045
GSE145323,GSE145324_1_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.25094
SEL1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13675
E2F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9941
WASF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73168
GSE214823,GSE214824_0_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Dopaminergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.648
OAW42	DepMap CRISPR Gene Dependency	1.0	3.37679
GSE175787_5_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE174498,GSE174500_2_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
NPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29703
Psoas	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.556
CLPTM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45418
GSE126127_0_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC2A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97691
TTLL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32206
SUPT1	DepMap CRISPR Gene Dependency	1.0	2.87577
GSE231720,GSE231724_2_v_1_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7303
PCED1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63295
GSE111660_2_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.0118
NFIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85895
GSE210580_0_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
INO80D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8635
MYCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95495
WDR55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04046
PMC6599263-13073_2019_654_MOESM2_ESM.xlsx-CAR1_tsv-gene_name_NR1I3	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37156
PMC12478272-mmc1.xlsx-Table_S7-Supplementary_Table_7_Proteome-wide_MR_and_sensitivity_analysis_results_using_the_brain_pQTL_dataset_from_Wingo_et_al_1_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.62946
LYSMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07034
BSDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99994
ATRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47043
SCML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57594
GSE210885_2_v_1_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE226249_5_v_4_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE182680,GSE182683_7_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13476
TEAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17686
GSE216273,GSE216292_14_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Conceptus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.982
SEC14L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69977
GSE60837_2_v_3_bcl9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE64642_0_v_1_sirt6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Spleen	GTEx Tissue Gene Expression Profiles 2023	1.0	1.10802
GSE248045,GSE248046_6_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Zic3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.1135
GSE139016_3_v_2_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Mafb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.54
VPS9D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75877
GSE210885_0_v_1_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE155695,GSE155696_1_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ALCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.662
GSE256181_1_v_0_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210580_0_v_12_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE220520_3_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE195568_1_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CDCA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38089
MZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30952
PMC9882185-media-4.xlsx-Neuron_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SUDHL1	DepMap CRISPR Gene Dependency	1.0	2.40184
RAB3GAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88741
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	53.5688
DUXA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35317
PPM1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22435
CDC37L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82286
SLC11A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49003
GSE114284_2_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TMEM168	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.966
SLC8A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5781
ANAPC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03596
RUNX1T1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82772
SW626	DepMap CRISPR Gene Dependency	1.0	2.72128
GSE161055,GSE161056_1_v_0_hira_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CASZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86514
GSE191105_2_v_3_nat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DIABLO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41544
ERF::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.1059
BAIAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18498
GSE150134_1_v_0_fluorouracil_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34936
JMJD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01342
GNL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86045
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Unnamed_13_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.90793
EIF4G3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13021
SUPT16H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76573
PABIR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84484
CD37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77802
H2AC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41174
SURF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41019
HINFP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9938
GSE178113,GSE178116_0_v_1_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TEX13B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99697
TTC39C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65964
SKNSH	DepMap CRISPR Gene Dependency	1.0	3.32717
Hippocampus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TMEM30B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14571
EMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06769
GSE172016_2_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
NAMALWA	DepMap CRISPR Gene Dependency	1.0	2.61415
GSE131161_2_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.303
TUBA1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40287
Twist2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8894
TCTN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12359
GSE123825_0_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_10_v_6_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
RXYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92334
GTPBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31355
GSE149035_2_v_0_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11611169-pone.0314092.s001.docx-3-PPARG_PPARG	Rummagene Transcription Factor Associations 2026	1.0	null
BCDIN3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19887
PDS5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20947
DAPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13008
TANGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00308
GSE114284_1_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE128240_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE215086_3_v_7_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE97278,GSE97280_2_v_1_nsd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OGFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80339
P3H4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0775
PHKG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4401
t60-adrenal_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.3844
UNC13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01368
GSE184210_0_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1742
GSE119498_0_v_7_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NOC2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07837
ZNF549	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.0203
Nr1h3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.2136
GFI1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04343
DDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66356
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE108614,GSE108615_3_v_2_setd1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DU145	DepMap CRISPR Gene Dependency	1.0	2.07087
MRPL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19956
Zic1::Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	51.2257
PHF23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59088
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3301
DDX28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60644
LOUNH91	DepMap CRISPR Gene Dependency	1.0	3.10199
C2CD4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26152
RBPJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65982
Nr1h4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.6197
YTHDF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69484
UBR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81305
SLC43A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9237
MBOAT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11507
GSE248045,GSE248046_0_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE239844_1_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE74251_0_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE157911_1_v_0_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SIPA1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62621
EW22	DepMap CRISPR Gene Dependency	1.0	2.18502
GSE210580_0_v_2_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ASB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63199
HAND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35932
GSE196104,GSE196106_3_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GLIS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72783
PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT38_Protein_cis-instrument_MR-eTable_38_Cis-instrument_Mendelian_randomizaion_screen_of_1_901_cortical_proteins_on_lifetime_smoking_behavior_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
POLR3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91454
DSG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98829
GSE162087_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TRIM56	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86008
GSE223008_9_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE248045,GSE248046_6_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SULT4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11833
GSE139016_0_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
PGBD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36273
PMC5637904-PATH-243-193-s016.xlsx-human_up_in_fat_SOX11-Unnamed_6_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
PPHLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81853
GSE213632_3_v_5_acod1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10510228-13287_2023_3481_MOESM7_ESM.xlsx-DEGs-Differentially_expressed_genes_DEGs_in_bone_marrow-derived_MSCs_from_six_human_donors_cultured_at_high_confluency_MSC-HC_versus_low_confluency_MSC-LC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
PEX13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12123
GSE198165,GSE198166_7_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TNRC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84361
GSE100528_1_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AADAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33298
GSE236262_0_v_3_trim28_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
IFIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15877
MTARC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62119
SLC35B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91801
AM38	DepMap CRISPR Gene Dependency	1.0	4.48663
FOXK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7147
COL6A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40783
CHAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44451
RUSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80749
ZFP57	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2269
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.16618
GSE180185_9_v_5_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EM2	DepMap CRISPR Gene Dependency	1.0	2.65459
MBOAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36822
LCLC103H	DepMap CRISPR Gene Dependency	1.0	2.62825
GSE102505_5_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
STX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84735
Salivary gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZNF585A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58656
PCYT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17615
SNU13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75074
NR0B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7851
SMARCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82676
XPO7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58067
GSE221004_3_v_0_prdm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216273,GSE216292_0_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ABI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34139
NCIH1755	DepMap CRISPR Gene Dependency	1.0	2.04325
GSE178255_1_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
SLC45A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26906
PITPNM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03922
GSE158834_11_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE234340_12_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HOXB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90726
ZNF676	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38427
KARPAS299	DepMap CRISPR Gene Dependency	1.0	2.6845
GSE216043_10_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE240027,GSE240030_1_v_3_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ALS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10447
CCNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84099
GSE210580_0_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32764
UBE2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39395
TNPO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56582
MSH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19412
PMC4219345-1471-2121-14-52-S3.xlsx-BORIS_hNP1-Gene_Symbol_CTCFL	Rummagene Transcription Factor Associations 2026	1.0	null
GSE126345_4_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GLI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42927
Occipital lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.698
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.875
TIMM50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57227
SNAPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55154
EBF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92424
GSE122425_1_v_0_nsun2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PSMB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07909
IGROV1	DepMap CRISPR Gene Dependency	1.0	2.93164
GSE210682_2_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
NKX2-5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77096
Lateral ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Cervix - Endocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	2.16694
GSE203308_4_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE198165,GSE198166_7_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9894241-pnas.2211429119.sd05.xlsx-G4_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF542P	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.73681
ZSCAN21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72328
Neuroendocrine cell_Trachea_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_name_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
PIK3CD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48374
NB4	DepMap CRISPR Gene Dependency	1.0	10.548
SEPTIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56955
GSE123825_0_v_3_glud1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE68156_0_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZBTB33	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2496
GSE175787_4_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
NFATC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42636
GSE158834_0_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE233566_1_v_2_braf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ALPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10481
GSE119498_0_v_10_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE173873_8_v_13_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE123825_2_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE224096_3_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CBX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23854
CUL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68495
ZNF454	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	118.429
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.8003
GSE112358,GSE112359_0_v_1_med23_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_3_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
HSFY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17109
GSE239844_4_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PNRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09139
TYW3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89997
MASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9051
GSE110248_1_v_6_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.5834
Crohn's disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.639794
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.4783
GSE180200,GSE180201_3_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hypertrichotic osteochondrodysplasia Cantu type	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.92
GSE142684_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE144231_4_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AP1G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50667
GSE214382,GSE214383_1_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26536
HSC5	DepMap CRISPR Gene Dependency	1.0	2.53566
GSE215086_1_v_7_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
CREB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1204
GSE202603_3_v_2_bhlhe40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TOPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45249
PMC7870953-41540_2021_169_MOESM9_ESM.xlsx-RREB1_targets-target_gene_RREB1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149880_2_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SETD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16358
GSE158431_2_v_3_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NKX3-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25469
ARL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76725
PTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87933
PARP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28964
GSE98831_1_v_0_brca1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8224457-MSB-17-e9760-s005.xlsx-C_Ctrl_v_HMGB1-KD_IMR90-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HELT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53669
GSE167373_0_v_3_rbfox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE116930,GSE116935_3_v_0_hes7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MGAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80514
SHOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94487
TMA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74786
GSE126345_9_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100596_FWM_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.02364
GSE186707_1_v_0_hdac4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE102675_3_v_0_atf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AJM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83821
GSE65617_0_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AP5S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56059
UBE2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3684
RABAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97658
GSE172020_0_v_2_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PLXNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.674
GSE145915_5_v_1_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE126345_7_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZDHHC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5661
GDE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86312
GSE144231_6_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ATG101	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39016
GSE180200,GSE180201_3_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
WDR43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20528
GSE109530,GSE109531_2_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE180185_4_v_10_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TMED3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27661
ARL5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04181
CSPG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1462
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.4142
DHX58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5791
ZNF786	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48806
GSE158431_2_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HT1197	DepMap CRISPR Gene Dependency	1.0	2.84523
DARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19175
UBL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37903
METTL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44323
FIGNL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94237
dm15	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.154
AAMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73313
GSE174383_4_v_7_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE87412,GSE92423_2_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TMOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11651
GSE114284_4_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KHDRBS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24514
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.08929
PMC8569982-41065_2021_205_MOESM1_ESM.xlsx-mono_THP1_a2b_tpm1-gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
496100453_HIP_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.16972
TDRD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80088
MTMR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48181
ZNF503	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09233
GSE173201_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ERI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.61342
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6804
ZBTB26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50547
PUS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55742
OTULIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99736
GSE93674_1_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTNNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84713
GSE158834_10_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
TAF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08334
PMC12486367-Supplementary_Data2.pdf-327-ZNF263_ZNF263	Rummagene Transcription Factor Associations 2026	1.0	null
TSEN34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32855
GSE139987_1_v_0_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
USP53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31585
ASGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17187
GSE232631_5_v_2_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6113333-41598_2018_31192_MOESM11_ESM.xlsx-Sheet1-H1_NFIC_NFIC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149035_1_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
LPAR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12184
JHH6	DepMap CRISPR Gene Dependency	1.0	3.08283
GSE248045,GSE248046_0_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE214823,GSE214824_5_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.3116
ZWINT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71003
JAK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05473
EIF2AK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.17494
DMTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97516
ZNF275	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89632
GSE174383_4_v_0_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE141726,GSE141733_1_v_0_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HIVEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93835
ABHD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38713
GSE244072_10_v_1_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE171401_1_v_2_adnp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE162688_1_v_2_pink1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE95771_0_v_2_ruxolitinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_10_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
DGKA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25489
GSE97278,GSE97280_2_v_3_nsd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE180200,GSE180201_2_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PRKCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49644
DVL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3642
C16orf87	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92932
PMC5637904-PATH-243-193-s016.xlsx-human_up_in_fat_SOX11-Unnamed_7_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
GSE234340_9_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210580_4_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE215351,GSE215794_4_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Diencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.619
GSE60837_6_v_3_bcl9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MYOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73494
MTMR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56611
PMC8384902-mmc5.xlsx-H128_ASCL1_ChIP-Symbol_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
FAM83D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37514
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-19q13_43_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
RBM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30269
GSE114284_4_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE214514_1_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.90559
MBIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1744
MRPL14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26972
NR2E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14968
PLEKHG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57965
GSE217405_0_v_1_osimertinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE210682_0_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE145215_0_v_3_krt13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE90821_3_v_1_esrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216273,GSE216292_0_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GJA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97126
NSUN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01271
GSE87404,GSE87812_1_v_0_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PHACTR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51943
GSE146962_0_v_1_glucosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ACTR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75243
GSE93674_2_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF384	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07813
GSE252958_1_v_0_znf469_human	RummaGEO Gene Perturbation Signatures	1.0	null
PLXND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41338
GSE188870,GSE188871_4_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE173201_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TRAM1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2192
Ascl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	47.9702
PRICKLE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39589
SEMA3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90969
GSE149035_3_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE81803,GSE81912_0_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAP3K14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53632
GSE164521_0_v_1_nitric oxide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FANCM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4225
ZNF354C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33716
Hypothalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.619
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4375
BIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1554
GSE90019,GSE90020_5_v_2_phf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE157555,GSE157556_4_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.424
SOHLH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77081
GCAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20759
C2orf81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11998
TAF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19549
GSE211126_3_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE212299_2_v_1_abi3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TLE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33306
KCNH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12246
TRIM68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29201
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.1076
MRPS21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93638
GSE124920_1_v_2_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE172020_0_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.2768
Synaptic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.813
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
MT1X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98545
GSE199660_1_v_3_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19508
GSE180200,GSE180201_3_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158834_10_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
ARL8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37184
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-E2A_Pre-Pro-B-Cells_ChIP-seq_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210580_5_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KINGS1	DepMap CRISPR Gene Dependency	1.0	3.32604
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.4298
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.63658
GSE123825_2_v_3_glud1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158834_1_v_6_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE102505_1_v_2_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12903452-mmc5.xlsx-ST2-2_OCT4_Off_Targets-Target_Gene_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
496100610_TCx_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0128
ALKBH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07893
GSE197562_0_v_3_nox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE89018_6_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE231720,GSE231724_2_v_0_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12108
SNU398	DepMap CRISPR Gene Dependency	1.0	3.20332
TFDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77876
POLR2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28638
TDRKH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97979
GSE198165,GSE198166_9_v_4_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157555,GSE157556_0_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE219195_1_v_3_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE131161_5_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TFIP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81218
ESR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.0023
GSE158834_11_v_5_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE176008_8_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAP1LC3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71337
SULT2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99184
RNASEH2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11713
GSE125153_1_v_3_bcl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OCIC4P	DepMap CRISPR Gene Dependency	1.0	2.21303
SLFN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41334
Prdm15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.9857
OVCA420	DepMap CRISPR Gene Dependency	1.0	2.63638
KCNG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58748
RAB38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8608
GSE217156_2_v_3_trpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE153836_14_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
IFI27L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96322
GSE129241_3_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-4_E2F8-Gene_E2F8	Rummagene Transcription Factor Associations 2026	1.0	null
GSE245270_2_v_5_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE229468,GSE229471_2_v_3_znf587_human	RummaGEO Gene Perturbation Signatures	1.0	null
CNOT6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40383
PSMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70029
RAPGEFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52986
NFYA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68629
GSKIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14158
GSE129241_4_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE245270_1_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE159446,GSE159449_1_v_0_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RNH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77208
TBC1D2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50245
DNM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18047
GSE123502,GSE123504_1_v_0_chd4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PEX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74292
TACSTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77875
GSE218580_1_v_4_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF37A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35353
GATA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08335
GSE63048_11_v_8_morc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
B-50 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.812
PMC5637904-PATH-243-193-s016.xlsx-human_up_in_fat_SOX11-Table_S5A_Upregulated_genes_in_tumours_from_DCIS-SOX11_cells_compared_to_DCIS-lacZ_cells_injected_into_mammary_fat_pad_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9894241-pnas.2211429119.sd05.xlsx-G3_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
SOX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26238
STBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57192
ZNF256	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54893
PHF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56336
GSE152032_3_v_2_s1pr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.0688
MRPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36251
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.43
PPAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37198
RIMKLB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70275
GSE200502_2_v_1_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80937
GSE226770_1_v_0_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MTX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98264
LS411N	DepMap CRISPR Gene Dependency	1.0	5.95003
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.68519
GSE153836_11_v_9_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE174498,GSE174500_2_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
IFT122	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81043
GSE126345_7_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
THOC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80316
PAX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.12735
PMC8567138-Table_2.xlsx-Sheet1-IGFBP5_AND_IGFBP7_NOT_IGFBP3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
SRSF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5768
CLIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64742
GSE116930,GSE116935_1_v_6_hes7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE115363_2_v_4_esrrb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158834_10_v_3_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF132	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.99372
Parietal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.804
GSE180185_7_v_5_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GLS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8739
TBX2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
KLHL24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40915
ZC3H12C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.782
GSE173873_2_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE213996_1_v_0_fhl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE173873_8_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182680,GSE182683_7_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
TP53BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36172
REM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14913
ANKS1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64123
GSE227891_2_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE169152_3_v_2_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE119498_6_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE144231_4_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE184210_0_v_1_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86141
MRGBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21312
GSE157555,GSE157556_3_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210885_0_v_4_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ENTPD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.72628
GSE218580_1_v_0_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3354
NHLH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48031
GSE198165,GSE198166_8_v_4_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PYCARD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73455
GSE81803,GSE81912_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RHOXF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06027
GSE179002_4_v_1_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain - Spinal cord (cervical c-1)	GTEx Tissue Gene Expression Profiles 2023	1.0	1.06394
GSE222574_0_v_2_lmna_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
C1QL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17539
GSE229468,GSE229471_0_v_3_znf587_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ENSG00000284691	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30719
GSE119498_0_v_5_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MGAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03324
GSE179002_4_v_7_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TMEM165	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52885
SASS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.5384
POLI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35047
NGRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02825
AGXT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39778
MAN1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7068
THEM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13044
HADH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36372
PMC5687749-pone.0188272.s005.xlsx-Supplementary_Table_3-Supplementary_Table_3_Differentially_Expressed_Genes_in_Common_between_AFX_compared_to_both_Keratinocytes_and_Fibroblasts_FOXO4	Rummagene Transcription Factor Associations 2026	1.0	null
DUT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65798
DCAKD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95211
PDAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25968
GSE129244_3_v_5_lmo2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KNS42	DepMap CRISPR Gene Dependency	1.0	3.21208
ZNF80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64924
RBBP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73581
FZD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6497
GSE198826,GSE198911_1_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE102505_5_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE193258,GSE193259_2_v_0_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SFXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99654
ZNF552	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60604
KCNC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08389
KLF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62201
PLEKHH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00151
GSE153836_11_v_2_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158834_1_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE218814_1_v_0_suv39h1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE190186,GSE190188_0_v_10_apoe_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LLGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41889
RPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34848
ODAD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86476
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RNF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15428
GSE111660_1_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BET1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12053
496100455_FWM_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.14974
A172	DepMap CRISPR Gene Dependency	1.0	4.1016
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5508
GSE185163_5_v_2_clic4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PNKD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53877
CRTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42581
USP9X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21614
GSE224096_1_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CLCN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44025
PYCR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1783
GSE182680,GSE182683_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC4860404-Table2.XLSX-MR_unique-Table_S2-7_DEG_unique_in_mouse_and_rat_SCI_at_3_dpi_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
CHMP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95993
GSE69244_1_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZFYVE9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6671
GSE125219,GSE125221_4_v_8_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9013128-NIHMS1795992-supplement-6.xlsx-ARID2_MUT_Dowregulated-Gene_name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
MNAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75254
GSE88819_3_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Tfcp2l1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.3576
TMEM59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95329
ACSBG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79752
ACSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58383
DST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36703
MAP2K7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95595
PGLYRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26584
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.8101
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4458
PMC4860404-Table1.XLSX-MR_specific-Table_S1-9_DEGspecific_for_mouse_rat_SCI_at_1_dpi_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
TBL1XR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46647
PMC12821819-40478_2025_2173_MOESM9_ESM.xlsx-Supplementary_Table_3a-Supplementary_Table_3A_List_of_Top_1000_Genes_with_the_Highest_Stochasticity_by_JSD_in_the_ATRT-MYC_Subtype_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
AFMID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33076
ACER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3475
C6orf141	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80247
ZNF474	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23856
PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_1_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE162276_4_v_0_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12179407-MCO2-6-e70261-s004.xlsx-up_TET3-KO_PQ_vs_Cas9_PQ-Unnamed_10_TET3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE189653,GSE203344_2_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE211126_3_v_4_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RFX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.3461
EP400	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73985
KIF2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5208
GSE116930,GSE116935_3_v_6_hes7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8447
PMC7870953-41540_2021_169_MOESM9_ESM.xlsx-ZNF423_targets-target_gene_ZNF423	Rummagene Transcription Factor Associations 2026	1.0	null
GSE239844_6_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE197686,GSE197688_2_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DPYSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67475
Germinated grain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.114
SLC25A46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.79928
RRP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39063
GSE158834_10_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
RORA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2472
LDOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29756
RIPOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08263
CAPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30982
GSE109530,GSE109531_2_v_0_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RNF103	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03498
GSE162276_4_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TSC22D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81722
PMC6344081-elife-40364-supp8.xlsx-PLZF-kd_2d_Diff_Vs_Ctrl_2d-diff-Symbol_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
GSE164135,GSE164137_0_v_1_fbxw7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Unnamed_1_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11058205-42003_2024_6202_MOESM5_ESM.xlsx-Data2c_CEBPA_ChIP-Unnamed_9_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
CBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12729
NTS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53187
GSE210580_4_v_6_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ATP13A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36777
NDUFAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65994
PMC6400843-Table_5.xls-C_FOXM1_Correlated_genes-Ensembl_ID_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE193258,GSE193259_2_v_8_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_upreg-human_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
HNRNPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41982
GSE228894_0_v_2_rnmt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE139966_4_v_2_figla_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE111660_4_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Glutamatergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.528
CWF19L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11627
GSE157684,GSE173391_0_v_1_rgcc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HEC251	DepMap CRISPR Gene Dependency	1.0	4.68032
chr19_46497711_A_C_b38	GTEx eQTL 2025	1.0	1.49646
TRIP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76107
PMC9533694-MOL2-16-3410-s013.xlsx-FIR20vsREST_DEMs-FIR20_vs_REST_DEMs_Down_REST	Rummagene Transcription Factor Associations 2026	1.0	null
FBXL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06321
GSE131887_1_v_4_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TRAPPC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83117
GSE119498_2_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE173873_2_v_13_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE124048,GSE124067_1_v_0_irf6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01791
GTEx Uterus 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	-1.0	-4.486
GSE100732,GSE100733_0_v_1_lrpprc_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37952
WEE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31799
ZSCAN31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30356
Caryopsis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.002
PLK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63463
SEC24A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45086
INTS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.0479
THAP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.647
GSE132948,GSE132949_2_v_3_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
chr19_46493759_C_CCGGCCT_b38	GTEx eQTL 2025	1.0	1.01969
PRR13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6624
GSE191021_1_v_0_nono_human	RummaGEO Gene Perturbation Signatures	1.0	null
CERS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71235
GSE217694_3_v_2_pold1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84353
FRMD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37724
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.0128
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
ZKSCAN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60027
GSE227891_5_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
COX6A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85818
GSE174498,GSE174500_5_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6400843-Table_5.xls-C_FOXM1_Correlated_genes-Symbol_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
CTRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41743
ATG9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18124
RIMKLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73607
GSE88819_11_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158834_11_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
QPCT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17109
RERFGC1B	DepMap CRISPR Gene Dependency	1.0	3.58606
GSE225735_1_v_4_aldosterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CDK10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03474
GSE112761,GSE112767_2_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE145323,GSE145324_3_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	6.15339
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_downregulated_genes-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
UPCISCC131	DepMap CRISPR Gene Dependency	1.0	3.06759
ZSCAN30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46486
SHROOM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44559
NAB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05664
GSE122509,GSE122513_2_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE181959_1_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
THOC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81179
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.4258
GSE195786_0_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RABL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00363
CHRNA10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12798
PDSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86605
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
KRTCAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31673
GSE151829,GSE151831_7_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FKBP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95318
GSE151829,GSE151831_7_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FAM117B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8557
HEXB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40727
GOLT1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24781
GSE126345_2_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DYNLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30951
ZNF574	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.3022
GSE157904_3_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MPHOSPH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.34697
NDUFA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5554
ENTPD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46569
MRPL32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37707
SIX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91708
GSE169263_1_v_0_armc5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF460	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81345
GSE137954_4_v_2_smyd3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE240027,GSE240030_5_v_0_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SRP54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21008
PRMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12756
PMC12534504-41598_2025_20489_MOESM1_ESM.pdf-443-ZKSCAN5_ZKSCAN5	Rummagene Transcription Factor Associations 2026	1.0	null
C6orf47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67016
HRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93944
USP36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18696
LIPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85294
C10orf88	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23098
TUBG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39878
PPME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61229
GSE240386,GSE242143_1_v_5_morc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE228261_0_v_1_elesclomol_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC4266008-mmc3.xlsx-iPS-MSC_vs_MSC-Unnamed_24_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
DOCK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41912
VILL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67335
GPRASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78671
GABA-ergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.095
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
GB2	DepMap CRISPR Gene Dependency	1.0	3.77224
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7984
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8244
RASL10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64355
MRNIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41711
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.30595
YPEL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95307
CORL47	DepMap CRISPR Gene Dependency	1.0	2.26127
ES4	DepMap CRISPR Gene Dependency	1.0	2.98491
GSE94814_1_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE174383_4_v_5_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FBH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97042
FAM98C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3923
TRIAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32573
ARFIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23625
GSE179002_3_v_1_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE200352_9_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RTL8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40874
ACSM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13837
GSE180200,GSE180201_12_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151782_3_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PCI38	DepMap CRISPR Gene Dependency	1.0	3.45418
GSE73562,GSE73563_1_v_2_preb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DNER	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74973
NHLRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20928
KDELR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4807
SIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56181
PMC11602576-mmc11.xlsx-ST12-Table_S12_Output_of_mash_model_of_milk_and_GTEx_eQTL_effects_Related_to_Figure_2_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
FKBPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37352
NEIL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82205
IQGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55359
ARHGAP39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2901
GSE175787_11_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Prdm14	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.7846
IGDCC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41634
Skin - Not Sun Exposed (Suprapubic)	GTEx Tissue Gene Expression Profiles 2023	1.0	3.65376
HEATR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77979
RAB3IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03779
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.363
127399	DepMap CRISPR Gene Dependency	1.0	2.83086
SLITRK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9333
REPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65866
GATAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97155
GSE148695,GSE167284_2_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EEIG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42982
GSE155852_0_v_2_apigenin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
APPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87836
S1PR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50323
GSE196671_5_v_0_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FKBP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59126
GSE129244_3_v_1_lmo2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SERPINE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56715
CAOV4	DepMap CRISPR Gene Dependency	1.0	2.45053
HNF4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10228
ODF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.02435
GSE133683_3_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MMP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41682
TUFT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51092
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.87835
Temporal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SKMEL30	DepMap CRISPR Gene Dependency	1.0	3.17286
GSE53538_1_v_0_cd2bp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAPKAPK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6722
496100507_FWM_dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.14439
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	80.4819
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.5457
GSE224096_2_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE235644_1_v_0_fasn_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LBH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77006
GSE88819_5_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PTPRZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4688
RILP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11794
ZNF766	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43293
GSE195743_1_v_4_lhx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE226770_1_v_6_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CLEC14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26651
SPRING1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79308
PET100	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10244
H2AB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58716
ZNF107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27108
Night sleep phenotypes	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.552288
GSE188870,GSE188871_0_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12629827-mmc8.xlsx-DDR2_KD-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90446
GSE147834_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
METTL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84647
UQCRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13407
ESD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73321
EIF3J	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7752
GSE236437_0_v_3_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_downregulated_genes-Unnamed_6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE95688_7_v_5_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE213228_4_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE225656_2_v_3_tsc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158834_11_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.0622
TROAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08497
NRBF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20808
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.2899
GSE144231_4_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FNBP1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48369
CCDC90B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.77832
Exocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SNX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56141
ASCL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03841
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.2196
GSE126345_0_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE88819_1_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RASIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07912
PTBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8022
PLOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02779
ZNF200	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56968
GSE174498,GSE174500_3_v_4_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S9-ZNF384_SpecDMCs-Unnamed_3_ZNF384	Rummagene Transcription Factor Associations 2026	1.0	null
GSE227891_2_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE123022,GSE123030_2_v_0_trem2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.6275
ICAM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18447
TESMIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.95765
BRD3OS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46496
PEG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46691
GSE120612_7_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MTMR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62397
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Differentially_Expressed_Genes_DEGs_of_OE-HIF1A_vs_OE-GAL4_Veh_in_Bulk_RNA-seq_Data_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
COL9A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06526
GSE135030_11_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE77108_6_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.75119
ARIH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58828
Fallopian Tube	GTEx Tissue Gene Expression Profiles 2023	1.0	3.85363
GSE205291,GSE205292_1_v_3_drd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE144231_2_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OLFML2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54889
GSE95688_7_v_2_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ACTL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49671
GSE158834_10_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF577	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27988
SOHLH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51278
ARFGAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1525
Extraembryonic tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.933
PDHX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02395
RERFLCSQ1	DepMap CRISPR Gene Dependency	1.0	7.28156
GSE128730_0_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
C18orf21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0916
GSE130437_2_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Ovarian surface epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.625
NCAN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57153
NB7	DepMap CRISPR Gene Dependency	1.0	2.13336
GSE89018_12_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DIS3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27375
PMC10319804-41467_2023_38747_MOESM10_ESM.xlsx-circARID1A_KD_genes_up-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6769
RIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06445
GSE210580_4_v_12_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SRP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36555
ITM2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42444
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.4627
TXNDC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78441
KHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22058
TBCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20449
GSE111660_1_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE162276_4_v_3_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
METTL27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07377
MAPK15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6444
GSE200352_9_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GPR161	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3744
POU3F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63321
PIAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78495
GSE211128_2_v_1_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
USH1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27093
GSE210885_2_v_4_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE120612_6_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
RXRA::VDR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0
CTAGE15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32053
GOLGA8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80561
GFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94978
GSE94849_7_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12211354-12915_2025_2224_MOESM6_ESM.xlsx-Sheet1-Sheet1_The_source_list_of_zebrafish_Npas4b_targets_from_human_NPAS4_targets_in_CHEA3_database_NPAS4	Rummagene Transcription Factor Associations 2026	1.0	null
SRSF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1475
GSE234340_3_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EML4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3767
TRERF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.673
Mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TSC22D4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3407
ABHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80006
GSE116492,GSE116495_3_v_2_stag2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7880998-41467_2021_21255_MOESM8_ESM.xlsx-Sup_Data_5_TWIST_Panel-Gene_Name_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
KIF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84022
USP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09168
BOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.84631
PARP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68379
MTERF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22479
RHBDF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08582
Ovary epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.557
GSE137818_2_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8224457-MSB-17-e9760-s005.xlsx-C_Ctrl_v_HMGB1-KD_IMR90-Gene_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TACO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50149
GSE174498,GSE174500_5_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
CGGBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56826
SLC25A25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8879
RPL27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02867
FAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45107
GSE149035_2_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
MMP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82138
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
TAMALIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55921
HCC15	DepMap CRISPR Gene Dependency	1.0	6.40534
TRIM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38454
GSE196699_7_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BIRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73755
MSS51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72879
KDM1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37442
H4C9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21742
GSE88819_3_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VCPKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84921
HNRNPDL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11452
PCDHB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45785
GSE217405_0_v_1_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE150349_0_v_1_msx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216043_7_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10149505-41392_2023_1393_MOESM2_ESM.xlsx-CPCMR-Hugo_Symbol_MEIS2	Rummagene Transcription Factor Associations 2026	1.0	null
TFPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30625
GSE79291_1_v_2_streptozotocin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE216043_7_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pparg::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	66.6956
ADCY9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51073
TCF20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96335
Corpus callosum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.037
GSE209548,GSE209549_0_v_3_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE111660_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE180200,GSE180201_15_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TFAP2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	130.098
NEUROD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87815
GSE211128_7_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
RPS6KL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08454
GSE136622_7_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Olig2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8375
TEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49707
496100346_FWM_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.47558
GSE247775_1_v_0_tmprss2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE180200,GSE180201_15_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NB13	DepMap CRISPR Gene Dependency	1.0	3.04521
GSE127790_11_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE248045,GSE248046_4_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210580_4_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7804
GSE199660_1_v_2_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE200099_3_v_1_honokiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAGOH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85112
SELENBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2134
HOSE cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.982
ZNF790	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31933
MARCHF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1057
Pituitary	GTEx Tissue Gene Expression Profiles 2023	1.0	2.71786
DZIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.313
RAD18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99636
GSE162276_4_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86119
Mhs	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.637
HNRNPAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.45198
GSE138019_4_v_6_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE174383_1_v_0_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Limbic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PRB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17076
GSE244072_10_v_3_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EOGT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44711
NAAA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43148
FBXW4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43182
GSE239844_1_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF365	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67613
GSE236454,GSE236456_0_v_1_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
C11orf96	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1166
TNFSF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81752
SIRT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80081
AJUBA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23917
GSE76183_2_v_0_ibrutinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF732	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19807
TIPARP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45461
BE2M17	DepMap CRISPR Gene Dependency	1.0	4.12012
POLR3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7805
EXOSC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04569
USP49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23516
GSE100464,GSE100465_0_v_3_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE169155_5_v_4_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
INPP5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31147
GABBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51576
POLD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35854
GSE153836_14_v_5_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNFX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19589
NME3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.59519
PRDX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12292
ZNF653	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31701
PSAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69051
MMACHC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42631
ABCD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09711
GSE158431_5_v_7_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE213228_2_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158834_0_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
HDA1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.643
MPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20856
BCAN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04989
GSE158197_6_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE179002_2_v_7_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE133763_0_v_2_chd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4547
ROS50	DepMap CRISPR Gene Dependency	1.0	8.78972
GSE166004_5_v_4_pld1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PDPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70734
ZNF529	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3817
GSE150134_1_v_0_scn5a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE164874_5_v_8_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54924