association	dataset	threshold value	standardized value
INSM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5417
NCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85145
GSE101546_3_v_5_setdb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ERGIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71501
GSE229468,GSE229471_2_v_1_znf587_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE129244_0_v_1_lmo2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ERCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53345
ADRA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17322
GSE216273,GSE216292_14_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
KDM7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22311
GSE218580_1_v_4_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.9519
EXOSC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25352
STX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38742
CXXC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30564
PCDH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10759
PPP2R2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16122
GSE63048_11_v_5_morc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE174418,GSE174421_0_v_1_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SDHC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65443
ANKRD13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.60867
SIPA1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24389
TMEM42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21893
KIDINS220	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24184
AMBRA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73803
GSE101546_3_v_4_setdb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_7979_KO_Hira_SRP179719	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.09796
GSE154464_0_v_2_cdk6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VPS13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53843
Pparg::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.7809
PRMT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62194
GSE89767_1_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NOA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25159
GLO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89491
RTKN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02338
CLUH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15995
GSE178227_1_v_2_tet1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80324
GSE261563_3_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TMEM218	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15671
LLGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41889
CDC37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45273
TRIM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26031
GSE195559_2_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PAFAH1B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36333
RPS21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55447
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.3114
RPS28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17592
NDOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70715
GSE112860_0_v_8_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE218580_1_v_5_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CPHXL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57806
PTPN18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.263
BIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22208
TUBB4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32027
RDH14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85493
GSE164483_2_v_0_venetoclax_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE216273,GSE216292_0_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTF2F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22265
SLC25A36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25371
ALDH6A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68025
PTCD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07163
THTPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6788
GSE190186,GSE190188_8_v_10_apoe_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GPRASP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60899
GSE154767_4_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DUSP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14805
GSE85880,GSE85881_0_v_1_tretinoin_human	RummaGEO Drug Perturbation Signatures	1.0	null
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4857
PAXIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19651
LANCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72493
GSE65617_0_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KCTD21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57171
ADAMTS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64832
ZNF771	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84775
CCNJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.25576
KLHL21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40134
GSE240386,GSE242143_1_v_5_morc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PAK1IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97385
CTSH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38076
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.7712
chr19_46435226_C_T_b38	GTEx eQTL 2025	1.0	1.90147
Intestinal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.511
SCAMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27164
GSE112763,GSE112767_2_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	51.433
GSE88819_7_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FAM210A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48161
GSE230263,GSE230265_5_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RPL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90445
HIPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77327
MCTS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49044
HOXA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32408
SLC30A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94244
GSE165579_3_v_2_opa1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CLDN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25381
GSE142684_4_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE192663_1_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MRPL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08904
PPM1J	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74689
ADCYAP1R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16251
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE139975_3_v_1_rnf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE147662_2_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
KDM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20184
C1orf226	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44164
CCM2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74786
GSE146074_10_v_3_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119978,GSE180930_0_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CREB3L4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2051
GSE211226_1_v_2_sirpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17309
CEP41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.75812
DNAAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61848
GSE107505_1_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE88819_3_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PNRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04007
FBXL22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8536
GSE173394_1_v_0_nfatc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE129389_0_v_5_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE107505_0_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DERL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0726
ZGRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70889
GSE158743_1_v_2_nfkbia_human	RummaGEO Gene Perturbation Signatures	1.0	null
HES1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9927
Zic3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.7987
GSE111138,GSE111149_1_v_0_runx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7322
MARVELD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47785
chr19_46427590_T_C_b38	GTEx eQTL 2025	1.0	1.18039
GSE180200,GSE180201_15_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE138024_2_v_0_rgs4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TRAPPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99229
LYRM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.95925
UFSP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6069
WASL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09804
VPS9D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82341
APOBEC3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60563
MSLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63673
PRXL2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39772
KLF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17082
PROM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50001
Perturb_12589_KO_Eed_SRP379883	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.14959
NYAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.54851
EDEM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21161
GSE239844_8_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TLK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98719
ISOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72265
GSE112860_0_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CCDC61	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90336
UBE2J2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47384
AUNIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3116
HCFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69033
CARMIL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51432
GSE210580_4_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ESRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62265
Perturb_13926_OE_HDAC1_SRP348264	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
PTPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31049
DNAJC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21882
AFF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20862
TRAPPC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34575
PIK3C2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1175
GSE112761,GSE112767_4_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19087
PSMG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2836
DSEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63828
CHTF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47092
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.1137
ZNF584	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45771
ATRAID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28415
GSE111660_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OGFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80339
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2835
GSE214382,GSE214383_5_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
KDM1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78139
ATP5F1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02017
MMP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41682
GSE112765,GSE112767_1_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ENPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21147
GSE114232_8_v_11_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE129241_4_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
ADAMTS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47517
RAD54L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9535
Perturb_6217_KO_Mef2d_SRP227204	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.6727
TATDN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30294
UQCRQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.71436
PPM1M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53034
DDX39A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.5781
EMSY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40947
Perturb_16943_OE_Mir181a1_SRP359086	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.2572
Inflammatory bowel disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.511
GSE174418,GSE174421_2_v_3_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LARP4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74888
GSE151829,GSE151831_7_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE198380_0_v_1_phgdh_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE192771_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MRPL42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83589
GSE148252_1_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_1437_KO_Kmt2c_SRP283007	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.694
GSE148252_7_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AURKAIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83564
EIF2AK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52256
MYCN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.608
NID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2043
ZNF350	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83713
UNKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35913
GSE181959_1_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PURA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4929
DDX20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6159
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.3462
TRAPPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52696
KRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40218
PDS5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20947
Perturb_16641_KO_Gaa_SRP277449	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.92504
PIGC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26374
TUT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.15192
ANAPC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37539
GSE112860_0_v_2_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE242199_9_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PSMD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66364
GSE165579_0_v_1_opa1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE119978,GSE180930_6_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95555
LENG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37492
GSE165682_0_v_3_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE226285_3_v_1_nr0b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZSCAN31	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.6979
ZNF749	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42157
PEX13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12123
GSE247862,GSE247863_2_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
USP46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39191
IRAK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51212
GSE207611,GSE207612_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12147031-NIHMS2026129-supplement-Supplemental_Material__Tables__Figures__and_original_Blots.pdf-19-ENSG00000269707_POU3F3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE147662_2_v_5_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MOV10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80999
CAMK2G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87096
ARFRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28701
MOB1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1121
CALHM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44369
GSE191021_1_v_0_nono_human	RummaGEO Gene Perturbation Signatures	1.0	null
LMAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8547
DNAJC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12683
NODAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.71059
C8orf82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35718
BPTF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31249
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9882
GSE122711_2_v_3_mpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OGG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41114
GSE210580_5_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H2AC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.77508
PRDM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75604
GSE174701_4_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE129370_2_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE89767_7_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PSKH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55992
GSE249714_0_v_1_anxa1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	49.582
ECHDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60151
TOE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45118
MRPS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73279
PITPNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07627
Perturb_6254_KO_CIC_ERP108370	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
SNRPE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68044
MGAT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5328
SESTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80054
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5981
RAB3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03553
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6049
ZNF221	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31937
GSE171292_5_v_2_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157555,GSE157556_5_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE247862,GSE247863_0_v_5_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB7C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26602
RPL36A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96495
Perturb_14472_KO_Cbfb/Runx2_SRP233168	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.93724
NF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86499
KDM3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16818
Creb5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.4701
GSE148252_1_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE224096_2_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PCNT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04796
GSE112860_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE236280_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
SMAD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.62336
KIAA1671	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73023
GSE112860_0_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WASHC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48855
GSE140607_0_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CSRNP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97996
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1397
COL6A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22559
GSE43041,GSE43044_0_v_1_ldb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.6102
H2AB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57229
GSE126777_0_v_1_otub1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MALT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17024
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.9612
UCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10632
TBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28329
GSE164874_5_v_10_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
POU5F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40378
CUX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13647
GSE191105_2_v_3_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PCNX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41109
GSE210580_3_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CCDC97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31752
GSE226285_3_v_1_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
GJD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34505
NDUFB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09476
ID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40117
PDCL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27392
KPNA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0376
MPHOSPH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00714
GSE154081_1_v_0_sildenafil_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTF3C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01779
GSE111660_4_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SEMA4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23244
PLEKHO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64746
GSE175883_0_v_1_dis3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SPZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2995
GSE190534,GSE190536_0_v_3_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TACC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31252
GSE119978,GSE180930_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZDHHC22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40172
FOXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49962
RIMS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48933
POLR2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45794
FOXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04617
GSE165682_2_v_5_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE189772,GSE189773_3_v_2_fbxo11_human	RummaGEO Gene Perturbation Signatures	1.0	null
CYP2U1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93323
GSE184479_1_v_2_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TNFRSF13C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39368
Perturb_3703_OE_Fst/Lin28b_SRP319706	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.61577
NINL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68891
GSE157296,GSE157298_4_v_5_kbtbd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
MPZL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31989
CHMP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30469
ATR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83225
TSSC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27441
Perturb_3663_KD_RBM26/RBM27_SRP243927	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
SWI5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48808
CETN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00945
KLRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04204
MRPL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38108
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.511
GSE174701_1_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZC3H12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2523
PDGFRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81725
GSE216274,GSE216292_4_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_6256_KO_CIC_ERP108370	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
ALDH4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51346
TKFC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34334
GSE174701_5_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52683
TPM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71709
WNK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37392
PLPP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51489
Perturb_14216_KO_Igf1r_SRP081104	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.2029
GSE205550,GSE205552_2_v_3_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE84148,GSE96938_3_v_1_nrros_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF785	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30578
ANAPC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03596
CXCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52706
SEC23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53322
PCED1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03323
RNASEK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70563
MED6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42717
TNNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.8067
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.6186
ALKAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84992
GPANK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34049
CWC15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61678
HNRNPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69445
EIF3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2619
GSE162688_1_v_2_pink1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57554
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1279
CDK11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19507
CAMSAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49378
PPP1R3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8314
GSE94849_1_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3195
ARL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55874
CHMP4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49065
ARMCX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59088
GSE186660_2_v_1_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
USP44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92254
ZNF543	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.43003
CIT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30858
Perturb_13977_KO_H3f3a/H3f3b_ERP109384	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.2256
GSE93674_2_v_3_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DPPA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78154
MTCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07787
GSE223334_1_v_0_bcl11b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10706
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE145311_0_v_2_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF432	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61925
GSE44157,GSE44163_1_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_4636_KO_lnc956_SRP359638	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
RFX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05043
GSE235234_2_v_3_corticosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HIGD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5511
CENPE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1632
H2BC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36721
CEP290	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03905
Perturb_4215_KO_Ezh2_SRP092451	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.20792
TAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84805
GSE48812_2_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MRPS35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90975
PNPLA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38109
SNRNP200	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24322
GSE148252_7_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6507
PDZD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76738
FOXP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09897
TADA2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68617
MAGED4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37771
NUDT16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57288
DPY19L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53082
PPM1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36129
SLC25A37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69879
CDK11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72158
Perturb_18004_KO_Lrp1_SRP220333	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.27757
GSE93124_0_v_1_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE153836_14_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RCC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60592
UNC119	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05018
EXOC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04491
STAT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22646
GSE232218_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ARL4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07573
SEMA6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41772
GSE60367_2_v_1_cxcr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ikzf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.6052
GSE73561,GSE73563_0_v_1_mef2c_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SNRPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23911
H2BC26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62887
CYB5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57733
PRICKLE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39589
ALKBH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49079
GSE190316,GSE190324_0_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE87862_0_v_1_mov10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SPRED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4087
MAPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58345
HEY1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.352
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5961
GSE94814_1_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CYTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.67639
THYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39372
TSNAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.70251
WARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09196
VPS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04699
GLMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1701
PCID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99115
PRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64005
MDM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10934
MESD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36181
REST	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.1869
PLEK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44204
GSE119978,GSE180930_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SDR42E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28626
GSE178714_5_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_4944_KO_Rybp/Yaf2/Prc1_SRP247114	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE109285_5_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SART1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60364
TMEM82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73899
GSE176093_2_v_3_mineral oil_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TRMT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81599
GSE210101,GSE210114_0_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TMEM150A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40047
GSE89767_6_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Spz1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.4167
GSE171401_1_v_0_adnp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE157555,GSE157556_4_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	78.5161
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.875
PTPN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74973
GSE119978,GSE180930_0_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
COG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63687
PRRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13279
LCN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11532
CEBPZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31942
TMEM238	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70379
AP1M2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33418
GSE178113,GSE178116_0_v_1_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE123022,GSE123030_2_v_0_trem2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TNFRSF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11726
GSE190316,GSE190324_0_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GORAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04719
ZBTB37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.9759
SPDEF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8554
SMPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11246
EIF4G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42647
FBN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53339
C19orf47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3997
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.511
GSE164874_5_v_14_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE156708_1_v_0_fbxo11_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CBY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00394
PDAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25968
PHACTR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32091
USP33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97911
TTC9C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25972
GSE191105_2_v_4_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NXPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70347
GSE129244_0_v_5_lmo2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GINS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83189
PRPF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29125
GSE174701_5_v_8_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE153836_11_v_9_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PSMG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48432
EIF4E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47933
Perturb_15770_KO_Uxt_SRP240277	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE109285_3_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
EIF3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12489
FBXO21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62149
FRAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64051
HCN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36996
MRRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92166
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6101
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.4285
LSM12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55621
GSE180185_7_v_5_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE214514_1_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16672
CCNA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51545
Perturb_3705_OE_Lin28b_SRP319706	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.35222
NLGN4X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90528
GSE157555,GSE157556_3_v_7_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14409
Perturb_10404_KO_Mettl14_SRP123442	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.29651
RPL35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48372
CALM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98828
GSE179002_2_v_7_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VASH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57152
TCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21386
ARHGAP27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57127
GSE174498,GSE174500_0_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE138024_2_v_3_rgs4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE144231_2_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57458
GPRC5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45545
C1orf159	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70926
GSE129241_3_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NECAB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5742
B3GALT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22986
LAGE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66501
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.2971
CHPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87367
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NUP88	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16939
B3GNT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52899
GSE180185_9_v_8_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TOMM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40986
GSE241701_1_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
WDR86	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87302
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.511
CTRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44671
ZBTB24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.279
CPSF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25078
GSE112761,GSE112767_2_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FAM234B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13901
ZZZ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77366
S100A14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80683
GSE92457_7_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FAM169A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18502
RAD18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.13446
CD2BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90697
CNN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0349
TTLL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49518
PIGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78843
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8692
LHX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45208
Crohn's disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.511
TIMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66638
ATP1B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28392
ZW10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23988
RAD51D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77718
TCF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7277
GSE138863_3_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE145323,GSE145324_1_v_0_rfx3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAFA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.2259
GSE142630_0_v_2_hiltonol_human	RummaGEO Drug Perturbation Signatures	1.0	null
ELK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.241
KIRREL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98426
ZFP82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62507
GSE111247_11_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE128333_2_v_0_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
STMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32284
SEMA4F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88463
TMEM107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04648
WASHC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02901
WRAP53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67093
GSE157555,GSE157556_4_v_7_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CNPPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56163
GPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64089
GSE118765_1_v_5_rreb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NUMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80672
FGF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61369
GSE155800_1_v_0_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_14475_KO_Trim28_SRP305340	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.38337
GSE246911,GSE246913_4_v_1_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210101,GSE210114_8_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ESRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83424
SPIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91915
PMC11003700-pbio.3002240.s013.xlsx-siMYCN_RNA_IMR32_48h_q_0_05_1_5-Table_S6_Genes_commonly_and_differentially_regulated_by_MYCN_and_WDR5_in_IMR32_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.6429
RBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78688
SPATC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44618
GSE247862,GSE247863_0_v_3_eomes_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
UQCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77524
Perturb_6178_KO_Bmal1_ERP113681	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.45823
MIS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57969
CSTF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69405
PWP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02116
KDELR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4807
PFDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29278
GSE157555,GSE157556_0_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CENPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87922
GSE138938_1_v_4_foxp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
RBM41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50207
GSE153836_14_v_5_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TAF1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3456
ANGEL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56338
BAZ1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55682
GSE216043_10_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE102505_5_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CCNDBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42455
TMEM256	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62057
ASB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18094
VAPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28431
DACT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15857
HNRNPU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07198
GSE69244_1_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
UBQLN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56421
GSE228894_0_v_1_rnmt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE122711_1_v_0_mpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IKZF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44673
SFPQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77623
GNRH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79704
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5291
GNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51573
NGLY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69444
POP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30632
GSE63048_11_v_12_morc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.578
UBE2R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36596
CALML6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36298
GINS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58825
GSE101239_3_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
VDAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98893
CREB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2512
Perturb_16086_KO_Bap1_SRP270239	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.18459
TANGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17427
GSE94849_1_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RHOXF2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10149
MTO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57304
GSE162688_3_v_4_pink1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.3574
TNNC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68172
NDUFB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75053
PRPH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61085
VPS26A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44943
IGF2BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66289
EPHX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38867
STARD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59099
RAD52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6474
GSE139239_2_v_5_ddr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67254
GSE154081_3_v_0_sildenafil_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PRR35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4966
KNTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27656
CLPTM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39108
EPB41L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70584
Perturb_14689_KO_Ffar3_SRP057302	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.1267
GSE119978,GSE180930_2_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23693
GRHPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20159
PMC7439574-13148_2020_914_MOESM2_ESM.xlsx-log2_fold_change_-2-1280_genes_are_more_than_four-fold_downregulated_in_PRDM8-_-_compared_to_control_PRDM8	Rummagene Transcription Factor Associations 2026	1.0	null
MBTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93107
SUPT20H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02599
GSE151829,GSE151831_1_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.81
GSE184133,GSE184137_1_v_9_esrrb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE101527_0_v_1_smad4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE165682_0_v_1_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H4C3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43599
PRUNE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44915
SENP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5584
GSE115363_1_v_5_esrrb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SYNRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88033
ZNF783	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33808
MPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54159
TTLL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18396
PSMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77599
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9743
PAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23902
LAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95398
EIF3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37033
GSE174701_4_v_7_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
HEY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9654
PGBD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01152
Dorsal raphe nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.878
ACER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3475
GRAMD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66803
ATP5F1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88918
GSE121809_1_v_0_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CAPRIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6732
GSE169263_1_v_0_armc5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210101,GSE210114_7_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF630	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58705
Perturb_12127_KO_Dnmt3a_SRP033096	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.26169
ZNF774	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72773
MYRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33333
APOBEC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28111
S1PR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81601
GSE176093_0_v_1_mineral oil_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FBXO41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06516
Perturb_15778_KO_Nmnat2_SRP360949	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.35045
GSE247862,GSE247863_2_v_5_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZFPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98728
SP140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35356
Zic1::Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.6568
H3C3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13854
RTN4IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88166
C17orf107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58285
B3GNT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00777
GSE233679_14_v_8_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ATM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67878
HOXA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46326
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PACS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40676
ATP11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38626
GSE148514_0_v_1_rreb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.502
NECAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11286
POM121	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27664
UQCRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13407
RNPEP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79315
GSE211983_0_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
EXD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08678
KIF5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03063
PPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36743
MORC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.69927
SMG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3805
GSE111385_2_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DHX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3872
ZNF729	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93301
TMED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62243
GSE174701_5_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HES5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6529
CIAO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87359
VWDE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72188
E2F6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32315
GGTLC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73116
NACA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47383
CSNK2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42724
GSE90019,GSE90020_5_v_2_phf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_6177_KO_Bmal1_ERP113681	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.50593
GSE180641_0_v_1_zfp503_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE176008_7_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZDHHC24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00382
SMIM24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04497
PIP5KL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00767
FOXO3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36466
JMJD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01342
GSE88819_6_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216274,GSE216292_4_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE216273,GSE216292_14_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF770	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.6083
DEF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12338
MFF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99543
PFKFB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43935
SLC1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55642
PACC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39329
GSE135350_3_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
RGS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57425
ARHGAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37029
PPDPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03801
GSE102467_3_v_2_pazopanib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE142684_0_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_11_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE147662_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CD276	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89985
GSE144231_2_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE239898,GSE239899_1_v_0_hiltonol_human	RummaGEO Drug Perturbation Signatures	1.0	null
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4628
BRI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44594
GNPTAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46029
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.892
NRSN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42009
GSE110178_5_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PANK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87243
DNAJB12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46201
DPRX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2382
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.488
GSE190316,GSE190324_1_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE73381,GSE73382_0_v_1_hira_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HSD17B10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86083
PSME2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04333
GSE107505_3_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ERMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78367
UNG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83111
GSE210580_3_v_2_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE133329_0_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
GK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71186
GSE181959_3_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
VPS37C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33419
Perturb_16947_OE_Mir181a1_SRP359086	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.48156
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8403
GSE212299_2_v_1_abi3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HEXA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76108
THNSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3391
SEC14L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67545
MT-ND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20324
SMARCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88841
Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	43.2427
GSE210150_0_v_1_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.089
GSE126777_3_v_1_otub1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MBOAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15992
RPS25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3174
Perturb_17296_KO_Sox8/Sox9_ERP014609	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE242199_9_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
DZIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83222
GSE101537_4_v_2_neurog3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CIDEC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10572
GSE111660_1_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DNAJC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37844
GSE139016_0_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
RNH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77208
DRAXIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67953
RAB7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52072
GSE227891_5_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF518A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01442
ZNF480	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44542
PTTG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30054
Perturb_7031_KD_Casz1_SRP038989	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.47526
GSE112763,GSE112767_4_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LFNG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47989
MARCHF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38745
TBC1D10A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68925
GSE221327_5_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE129389_0_v_6_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_1089_OE_hMAPT_SRP192566	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.54045
GSE211286_4_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZGLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2812
PDGFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9592
HOXC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5436
MAP1LC3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64058
TFAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30256
GSE112763,GSE112767_2_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
INO80C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.44033
TBX20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12289
GSE179002_2_v_6_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_3_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WNT5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00829
ARPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47449
GSE201270,GSE201272_5_v_3_mybl2_human	RummaGEO Gene Perturbation Signatures	1.0	null
VPS18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47307
PMC8554124-DataSheet2.XLSX-57-CEBPD_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
MED16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78791
GSE153836_11_v_2_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32384
TRPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10458
GSE111247_2_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null