association	dataset	threshold value	standardized value
GTEX-QEL4-0926-SM-3GAD1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19633
Large_Intestine-gut endothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0667499
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K58614056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34647
CABP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76561
BRD-K19011391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.0405
VDR-33458620-PRIMARYEPITHELIAL-HUMAN-PROSTATE	ChEA Transcription Factor Targets 2022	1.0	null
Plasma membrane raft	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.437
Dilated cardiomyopathy 1H	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.032
Brain Lower Grade Glioma_LGG_TCGA-TM-A7C3-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20095
periventricular stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16197
GTEX-WEY5-0226-SM-3GIKN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15219
ADSS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74564
BRD-A29371732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64197
INHBE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72965
pancreas	GTEx Tissue Gene Expression Profiles	-1.0	-0.946917
BRD-K69349031	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17827
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.121
PMC9883165-41375_2022_1744_MOESM3_ESM.xlsx-RNA-Seq_of_CEBPA_specific_genes-Unnamed_1_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q4-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DHX34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93459
GTEX-Q734-0326-SM-48U15	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00631
Lung adenocarcinoma_LUAD_TCGA-50-5055-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BE-10-NK39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.2662
MESP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01087
GTEX-S33H-0008-SM-4AD6C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39282
BRD-K80877725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10597
posteromedial visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03134
TBX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29233
Anterior olfactory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22503
GTEX-RTLS-1326-SM-46MUN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848247
CRCGN008_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4287
ATM_KD_GSE54268_663_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-X4XX-1126-SM-3NMBY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09162
GTEX-PLZ4-0008-SM-48TE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64482
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.75778
ETS1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ2-1726-SM-4DXUP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26085
GTEX-O5YU-0008-SM-4E3I7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.09762
BRD-K00300115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00792
CCDC127	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0715
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Anterior olfactory nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19715
BRD-K70566686	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.60022
Entorhinal area, lateral part, layer 2a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20649
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K37328981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08836
primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26543
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.882163
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18333
TAL1	ENCODE Transcription Factor Targets	1.0	null
SGSM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59247
intermediate stratum of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43356
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6338-01A-12R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RNOR-0826-SM-2TF5C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43726
UMPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76695
EMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79507
muscle cell differentiation	GO Biological Process Annotations 2023	1.0	null
paraventricular nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19986
Lung adenocarcinoma_LUAD_TCGA-55-6986-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Emery-Dreifuss muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.48
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PO-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF805	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01826
NCIH2122	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60042
PCDHB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76513
GTEX-NFK9-1126-SM-3LK78	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.948403
inner CP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15046
KLF1	ChEA Transcription Factor Targets	1.0	null
GSE150072,GSE169209_4_v_11_qser1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TBX2-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE203072_2_v_3_rpl3l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A183-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSMB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62225
plant vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.821502
rostral migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13286
mantle zone of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22195
PMC9733061-13059_2022_2800_MOESM5_ESM.xlsx-Table_S4-Table_S4_Genes_assigned_to_JUNB_binding_sites_Each_peak_was_assigned_to_the_nearest_TSS_JUNB	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K22087390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88538
ALDH4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57167
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01258
Endocardium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.46
BRD-K31210612	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03964
Sinus node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.518
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GD-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K70712801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88575
Thymus-mast cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0667499
KCNE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07069
H3K36me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JJN3	DepMap CRISPR Gene Dependency	1.0	3.1946
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hypocotyl	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070835
KCNJ14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37215
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.905154
MED13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83956
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3473-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell-cell contact zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.73
Sarcolemma	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GTEX-WZTO-0011-R4A-SM-3NMC7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.909974
GTEX-XBEC-1326-SM-4AT69	GTEx Tissue Sample Gene Expression Profiles	1.0	0.985402
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WG-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU4F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.22102
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.23728
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14739
ASH2L	ChEA Transcription Factor Targets	1.0	null
MDA MB435	BioGPS Cell Line Gene Expression Profiles	1.0	0.956896
POLR2AphosphoS5_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.6555
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34449
BRD-K61861910	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18755
GSE146962_0_v_1_glucosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-4304	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
laminin-2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.786
r6 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35041
HT29	BioGPS Cell Line Gene Expression Profiles	1.0	1.27789
E2F6_02_205	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.66382
BRD-K10954923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5438
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13277
CKS1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4759
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.32566
stratum pyramidale of caudal CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0183
ISLR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78275
BRD-K27433204	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01193
ZCCHC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99069
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.49756
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8600817-12951_2021_1120_MOESM2_ESM.xlsx-Table_S4-Table_S4_Pan_PPAR-iMSC-EV-induced_differentially_expressed_genes_in_fatty_acid-treated_HepG2_cells_PPARA	Rummagene Transcription Factor Associations 2026	1.0	null
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.89404
CD177	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56563
PMC10592471-NIHMS1912771-supplement-4.xlsx-D-HEp3_UP_NR2F1_ind_UP-NR2F1_Ind_UP_NR2F1	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.5186
NUFIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35494
TMEM259	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49761
JC-06-ED36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.58189
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TPM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52953
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GNPTG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34646
FOXD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.05
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52939
IFT20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53266
YOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87353
CTNNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4628
GTEX-R3RS-0526-SM-3GADG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87898
GSE158715_3_v_0_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K20355073	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24683
GTEX-REY6-1026-SM-2TF4Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19235
PMC8020666-pnas.2015855118.sd05.xlsx-LPS_24_AAM-Hg_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Alpha thalassemia-X-linked intellectual disability syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.24
NMCG1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.35305
Adenocarcinoma	CTD Gene-Disease Associations	1.0	1.01099
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5574-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-DX-A48R-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CERS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18953
GTEX-XLM4-0011-R9A-SM-4AT45	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889578
Brain Lower Grade Glioma_LGG_TCGA-HT-7616-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BB-20-UU03_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.202485
TPD52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01025
plexiform layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20189
GTEX-NL3H-0011-R5a-SM-2I3GB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845807
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-RXRG_RXRG	Rummagene Transcription Factor Associations 2026	1.0	null
CH25H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24383
GTEX-XGQ4-1526-SM-4AT6H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892546
SKNAS	CCLE Cell Line Gene Expression Profiles	1.0	2.4471
UAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62178
GTEX-V1D1-0626-SM-4JBHN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08918
MCCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18375
RAB14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90802
ATP6V1G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.924
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.50462
myocardium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.558856
primary motor cortex (area M1, area 4)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.89332
GTEX-PW2O-0008-SM-48TEB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.90633
CDC42EP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28326
GSE209598_0_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
subbrachial nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56476
GTEX-WWYW-1326-SM-3NB2S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06158
UMUC7	DepMap CRISPR Gene Dependency	1.0	3.56992
BRD-K77578964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16399
GSE103068_0_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Infralimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21319
primary visual cortex (striate cortex, area V1/17)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09311
CETN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77732
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10321
MSANTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17405
Lung-pericyte cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.065061
Heart-macrophage	Tabula Sapiens Gene-Cell Associations	1.0	-0.0594311
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863257
BHY	CCLE Cell Line Gene Expression Profiles	-1.0	-1.76551
MNAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66475
VMRCRCW	DepMap CRISPR Gene Dependency	1.0	2.99656
ZNF687	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84001
GTEX-PWCY-0526-SM-2I3ER	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52587
HCC1187	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.640587
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	1.0	0.888216
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K93484038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30903
KIF21B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45203
HHEX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21115
MYL3	MSigDB Cancer Gene Co-expression Modules	1.0	null
RASSF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04097
GTEX-U3ZM-0826-SM-4DXU6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03822
GTEX-S7SF-0526-SM-3K2BC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.1891
STAT3-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.80713
GTEX-U4B1-0326-SM-3DB8K	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02785
BRD-K26074237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29362
TFDP1_02_71	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59192
CAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12856
RAB15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17886
RND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02787
BRD-K14350179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39567
GSE136627_2_v_1_hdac4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1202
LMTK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.55859
GTEX-OIZG-0008-SM-4E3J2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44038
Lung adenocarcinoma_LUAD_TCGA-86-8671-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
colorectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.0558
GTEX-R53T-0926-SM-3GADH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32935
GTEX-UJHI-0426-SM-3DB8Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59075
FOXA1-33576154-HUMAN-HILARLN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
16643655-1300GenesList	GeneSigDB Published Gene Signatures	1.0	null
EB1	CCLE Cell Line Gene Expression Profiles	1.0	1.54792
Prostate adenocarcinoma_PRAD_TCGA-G9-6496-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U4B1-0826-SM-4DXTW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02537
GSE127790_6_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X585-0008-SM-46MU4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36586
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
LB2518-MEL	GDSC Cell Line Gene Expression Profiles	-1.0	-1.94475
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.905581
GCNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01919
precommissural pretectal domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04786
BRD-K92300676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05232
GTEX-X4XY-1726-SM-46MVO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0174
r7 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22429
heart development	GO Biological Process Annotations 2023	1.0	null
GRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12478
YIF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8695
NCI-H1734	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.17635
HOXB9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8315
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4843-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19707
GTEX-XBEC-0008-SM-4AT3X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.928863
Prostate-fibroblast	Tabula Sapiens Gene-Cell Associations	1.0	-0.0667499
GTEX-S4Z8-1826-SM-3K2BH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851129
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0846
Long QT syndrome 8	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.197
gramine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.13991
BRD-K31408750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25877
INO80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02775
Sarcoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.407
GTEX-U8XE-0008-SM-4E3K4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36274
GATA1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
17875932-TableS4	GeneSigDB Published Gene Signatures	1.0	null
GTEX-WFON-0226-SM-3GIKR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45143
RUNX1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7525
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TGFBR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91576
DNER	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91358
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.887329
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02553
GTEX-R55D-0008-SM-48FEV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61221
PMC12697342-jem_20250471_tables3.xlsx-large_int_SM-ILF_5_CXCL10-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.19314
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31612
HNF4A	ChEA Transcription Factor Targets	1.0	null
Nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38359
Prostate adenocarcinoma_PRAD_TCGA-J4-A67O-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96183
Anteromedial visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1221
Acute Myeloid Leukemia_LAML_TCGA-AB-2872-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_downreg-human_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S32W-1926-SM-4AD63	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35903
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.832785
GTEX-XPT6-0126-SM-4B65S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27799
ventrolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07801
MTAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39876
BBS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71638
posteroventral (inferior) parietal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.910718
Edinger-Westphal nucleus (accessory oculomotor nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04597
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context3-Nearest_Ensembl_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K49328983	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20604
GSE226114,GSE226116_2_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_4_FDC-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K05335635	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02339
SNU475	DepMap CRISPR Gene Dependency	1.0	2.57422
salivarygland_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.1068
ALG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58974
cyclic nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
hsa-miR-3677-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Uterus-nk cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0667499
CDCA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50633
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
abnormal body size	MPO Gene-Phenotype Associations	1.0	null
GTEX-WFG7-0826-SM-3GIKU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15915
SKMEL30	DepMap CRISPR Gene Dependency	1.0	3.76392
APOD_KO_GDS3913_487_mouse_Cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BNIPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2349
BRD-K67998155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1166
colorectum	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
dexpropranolol-6130	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_13920_KD_HNRNPK_SRP312616	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13328
lateral septal nucleus, intermedio-dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05788
PMC12623973-41467_2025_64981_MOESM3_ESM.xlsx-downregulated-c0_ACKR4_SCS_ceiling_LEC_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE123638,GSE123639_0_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9189
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_x_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2964
Sarcoglycan complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.457
SEMA3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54402
Adrenocortical carcinoma_ACC_TCGA-OR-A5LK-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YKT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61958
BRD-K50068274	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.08632
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05219
PICK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77277
Perturb_9492_KO_Mpst_SRP371858	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.89435
ZCCHC24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35978
SNX16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49139
ZKSCAN1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.85446
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1824
regulation of blood circulation	GO Biological Process Annotations 2015	1.0	null
cardiac muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31648
Sarcoplasmic reticulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.369
BRD-K85401814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39466
F12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67726
MYOD1_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JHOS4	CCLE Cell Line Gene CNV Profiles	1.0	1.35563
BRD-K87821938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98954
CCZ1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68438
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.9115
GTEX-T5JW-1426-SM-4DM5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02444
GTEX-UPIC-1826-SM-4IHKC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01716
DHRS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63573
LMO2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
FOXN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72135
GALNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82219
RBM18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60138
Vasculature-mast cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.065624
GTEX-X5EB-1426-SM-46MVW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954634
BRD-K53335788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46471
BRD-K68853384	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37474
layer 6 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51646
PITX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66928
GTEX-XXEK-2026-SM-4BRVE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70474
TEAD4_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
GSE176305_0_v_1_rotenone_human	RummaGEO Drug Perturbation Signatures	1.0	null
SW48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.963765
muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Rectum adenocarcinoma_READ_TCGA-AF-2692-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Posterior pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32518
GSE118617,GSE118619_0_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SYT12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97421
MYC	ENCODE Transcription Factor Targets	1.0	null
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.885643
GATA3-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
HCC1500	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36162
NSUN5P2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68219
MAX	ENCODE Transcription Factor Targets	1.0	null
GSE149880_0_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RAD21_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZG-1326-SM-2HMIQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906429
EBF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-XPVG-0726-SM-4B658	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34906
TP53-23651856-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XMK1-1826-SM-4B66F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837722
CRCGN014_HEPG2_3H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07986
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.879416
TCF23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6617
DMNB	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14854
MS-1	GDSC Cell Line Gene Expression Profiles	1.0	1.67012
SKMEL31	CCLE Cell Line Gene Expression Profiles	1.0	1.38732
RHOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25274
Kidney - Cortex	GTEx Tissue Gene Expression Profiles 2023	1.0	5.36944
TMEM231	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42097
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065228
skmel30	HPA Cell Line Gene Expression Profiles	1.0	1.01354
PPM1K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10884
RPL19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07444
superficial stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.87252
posterior (caudal) superior temporal cortex (area 22c)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11061
large intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055605
GTEX-T6MN-0926-SM-32PLX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48591
GTEX-OOBJ-0826-SM-3NB2K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872059
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.96737
paracentral lobule, posterior part, left, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0927
FLOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29663
mantle zone of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39303
NECAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11286
Spleen-regulatory t cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0661869
GSE185163_3_v_1_clic4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PLCB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45086
PMC2866657-pone.0010547.s001.xls-ERG-high-GENES_DOWNREGULATED_IN_ERGhigh_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SNMC-1126-SM-4DM5M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995371
TASOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39955
TBX5-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
LZTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77038
TMEM54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7054
mantle zone of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17195
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN013_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.26735
MAPK8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19544
Lung squamous cell carcinoma_LUSC_TCGA-98-A53I-01A-31R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KHDRBS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41066
GTEX-P4QT-0008-SM-48TDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.01883
I band	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.238
A101D	CCLE Cell Line Gene Expression Profiles	1.0	1.88982
intermediate stratum of PcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.53771
Pancreas-b cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0667499
GTEX-P78B-0426-SM-2I5F5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82803
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.19156
PARP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94913
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25701
mantle zone of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.76185
muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.781894
GSE228894_0_v_1_rnmt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08182
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.73758
Somite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.46
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.836238
BRD-K43834805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59361
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.946341
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.21574
r6 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81715
YBX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55276
BRD-K67980271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06737
17284527-TableS2	GeneSigDB Published Gene Signatures	1.0	null
GTEX-XGQ4-0526-SM-4AT6C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36167
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.391
CFAP119	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55415
CTDSPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11292
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.696
BRD-K61020385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32697
PMC11196699-41598_2024_61762_MOESM1_ESM.xls-Normal_v_Advanced-PRDM16_PRDM16	Rummagene Transcription Factor Associations 2026	1.0	null
FNDC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13707
HUT102	CCLE Cell Line Gene Expression Profiles	1.0	1.69128
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.606
GTEX-WHSE-3026-SM-3P5ZH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884678
DU4475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
NME3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59519
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.75131
CNOT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25986
PHTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02544
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.20496
SLX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96502
YY1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50784
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058372
BRD-K62236460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03454
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.59633
inner SZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.856344
Long QT syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.747
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.859073
PANX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10941
IL4R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77582
H3K4me1_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC11531655-MCO2-5-e754-s001.docx-0-IRF7_Regulon_1_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16971
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.885643
FARAGE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.86804
lateral pallium	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42543
MCF12A	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.900711
SW 837	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.1287
Sarcolemma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.982
GTEX-WH7G-0426-SM-3NMBJ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.18873
LD-69-ZV56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.362183
LRRC47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40429
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.74468
GTEX-QDVJ-0426-SM-2I5FW	GTEx Tissue Sample Gene Expression Profiles	1.0	2.96969
Lung Injury	CTD Gene-Disease Associations	1.0	1.06479
BRD-K78755361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00081
Hypertrophic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.262
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TP53	ChEA Transcription Factor Targets	1.0	null
GTEX-OOBJ-0326-SM-33HBO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80509
BRD-K03213425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40664
OSTM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41308
APLNR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06341
AKAP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98222
TCF12_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.31478
SKM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.979419
GTEX-XOTO-0008-SM-4GICE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50386
PMC9008061-41467_2022_29733_MOESM4_ESM.xlsx-ERRg_SE_peaks-Nearest_Ensembl_ESRRG	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K02927989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89732
Pericardium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.086
BRD-K86694287	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13822
JHH6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37636
Fibrosis	CTD Gene-Disease Associations	1.0	1.09297
Z disc	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.136
CF-24-KQ98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.358908
MYOD1	ENCODE Transcription Factor Targets	1.0	null
BRD-K31218318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6284
FOXP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90057
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Intestinal pseudo-obstruction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.09
SH2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55
TCF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46843
GTEX-OIZI-1426-SM-3NB1T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879332
Colon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Acute Myeloid Leukemia_LAML_TCGA-AB-2982-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K51385533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50776
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15281
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4166-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K30310008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25228
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7218
Fast muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.785
AC-93-LT43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.474957
GSE120595_5_v_4_arid2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MMS19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05468
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.928916
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4965-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MU-A5YI-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MECOM	ChEA Transcription Factor Targets	1.0	null
CISD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98864
superficial stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62845
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.942889
GSE89018_10_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K21176717	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04895
GTEX-S33H-0826-SM-4AD5Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.928579
FHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26441
COA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98465
HIPK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.31477
IDE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82469
IFT52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32121
GTEX-WY7C-1126-SM-3NB3A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1997
GTEX-OHPL-0008-SM-4E3I9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69995
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN013_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10848
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12568
ARMC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20539
GTEX-NL3H-0011-R4a-SM-2I3GK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31382
BRD-K35386584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.337
cellular developmental process	GO Biological Process Annotations 2015	1.0	null
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917533
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18446
Perturb_7115_OE_Mir378A_SRP047487	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-19.699
PDE5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07916
GNAQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4069
BOK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03929
slow postnatal weight gain	MGI Mouse Phenotype Associations 2023	1.0	null
H3K36me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.828792
CHP212	CCLE Cell Line Gene Expression Profiles	1.0	1.86273
EBF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7097-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.827037
juxtacommissural pretectal domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17192
Intrinsic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.777
integral component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.138125
GTEX-N7MS-0011-R5a-SM-2HMK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.851463
BRD-A95489119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02509
Costamere	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.378
REST	ENCODE Transcription Factor Targets	1.0	null
cardiac muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.931051
BRD-K10171338	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3044
BRD-K84260700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59379
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FO-11A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MZ in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0571
cellular process	GO Biological Process Annotations 2015	1.0	null
principal sensory nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.063
sodium-phenylacetate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53963
PMC4540202-cddis2014370x2.xls-Sheet1-Table_S2_MEIS2-responsive_genes_MEIS2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
vincamine-2327	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lateral septal nucleus, rostral (rostroventral) part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08974
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.79416
KIAA2013	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22077
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.32341
superficial stratum of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44825
Liver-fibroblast	Tabula Sapiens Gene-Cell Associations	1.0	-0.065624
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5441
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8375
NCIH1734	CCLE Cell Line Gene Expression Profiles	-1.0	-2.78363
Lung-cd4-positive alpha-beta t cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0667499
regulation of multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE231648_4_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE195559_0_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
FIBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36174
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10278
fenbufen-4279	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cyclic nucleotide binding	GO Molecular Function Annotations 2023	1.0	null
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.884189
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.606
liver	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.70768
CREB3L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86677
BRD-K51535480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27448
GTEX-WHSE-0011-R3A-SM-3P5ZM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.83273
hsa-miR-4286	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
KLF1-20508144-FETAL-LIVER-ERYTHROID-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
RT-112	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Taenia tecta, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41818
Nucleus of the brachium of the inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61351
TE1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.81875
CFAP298	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50696
Retrosplenial area, lateral agranular part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.04562
Lung adenocarcinoma_LUAD_TCGA-86-A4P8-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03929
KHSRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90412
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.90208
BRD-K86065375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65188
STK26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17161
SIK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67083
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.25872
GTEX-WY7C-2526-SM-3NB2N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873199
GTEX-O5YV-0008-SM-4E3HP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66024
CDHR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02044
GSE149124,GSE149128_3_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
urinary tract	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.22876
BRD-K85622666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.44211
ODAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94135
HIR complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.008
COG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63687
GTEX-X62O-0826-SM-46MW8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46792
hsa-miR-4793-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
NCI-H1155	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SF295	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.82566
BRD-K94145457	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03566
GTEX-XUW1-1826-SM-4BOQD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09178
BRD-K73210450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40092
PCLAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75791
GTEX-QEG5-0926-SM-2TC64	GTEx Tissue Sample Gene Expression Profiles	1.0	2.68939
H3K4me1_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ERLIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42523
SUSD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95858
CNN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41088
oltipraz	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23366
SUPT6H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68747
CREB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25598
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SIU7-0426-SM-2XCDX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66875
RBBP5	ENCODE Transcription Factor Targets	1.0	null
Interventricular septum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.955
GSE249146_2_v_1_dusp6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K93044218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03477
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TCF7L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58384
Entorhinal area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76487
Sinoatrial node disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.443
CAL62	CCLE Cell Line Gene CNV Profiles	1.0	1.34803
KLHDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66589
parenchyma	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.813979
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7091-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.223
Precommissural nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.03664
GSE122101,GSE122103_3_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Connective tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.634
Prostate adenocarcinoma_PRAD_TCGA-EJ-7328-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11258
ZNF280C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16951
GTEX-RWSA-0626-SM-2XCBD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4859
TAL1-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-4723-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
H1_BMP4_Derived_Trophoblast_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.843997
H3K4me1_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
arsenic trioxide_homo sapiens_gpl201_gse48441	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SFSWAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43299
FKBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46241
BRD-K33456231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16397
isotretinoin-2407	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RSBN1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36701
lateral part of JcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22148
GTEX-XQ3S-1126-SM-4BOPK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00951
H3K4me1_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NPAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47334
ZNF669	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50924
ZNF615	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03883
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SG in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.922799
GTEX-UPK5-0226-SM-3GAEV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28532
Prelimbic area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11152
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.993
USP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94783
WDR73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26411
GTEX-WHSE-0011-R4A-SM-3P5ZN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.918861
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4991-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUZC-0326-SM-4BOO8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950468
nicotinic acid-3381	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K53612850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03527
TTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35869
RH41	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45329
BRD-K00882360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16038
gastrointestinal tract	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Nkx-2.5 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.43
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.834445
GSE127790_11_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.56813
APOBEC3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3924
KLF1-20508144-FETAL-LIVER-ERYTHROID-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44622
GATA1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Heart septal defect	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.358
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8339
PMC9883165-41375_2022_1744_MOESM3_ESM.xlsx-RNA-Seq_of_CEBPA_specific_genes-RNA-Seq_analysis_of_genes_associated_with_a_DHS_that_has_a_CEBPAx2_specific_Hi-C_interaction_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE152937_12_v_1_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superior parietal lobule, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02553
CEBPD-23245923-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03605
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1309
PRPF40A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1541
H2AC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52059
ZNF768	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.74425
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01224
GTEX-NL3H-0011-R7a-SM-2I3G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22994
DUSP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95905
nucleoside phosphate binding	GO Molecular Function Annotations 2015	1.0	null
LE-40-JW92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.56975
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-BrtoFay_Thermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8309-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.15861
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX2-21211035-LN229-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
FB-66-UU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.207684
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.669948
F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14268
regulation of biological quality	GO Biological Process Annotations 2015	1.0	null
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4809
GTEX-PWOO-0526-SM-2S1Q3	GTEx Tissue Sample Gene Expression Profiles	1.0	2.19134
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NOXO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89008
superficial stratum of p2ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06381
C21orf91	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44562
GTEX-X5EB-0626-SM-46MVQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40885
RDH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4565
BRD-K13534347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.48847
TOX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70828
Acute Myeloid Leukemia_LAML_TCGA-AB-2859-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS20	DepMap CRISPR Gene Dependency	1.0	6.85001
SSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55587
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.41663
GTEX-PSDG-0926-SM-2I5FP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44534
PMF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02647
ACYP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37313
GATA4-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
G protein-coupled GABA receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.654
2-iodomelatonin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25472
LYRM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26797
BRD-K51363316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98037
intrinsic component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.096664
CRCGN014_HEPG2_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.87856
GTEX-WWYW-0011-R8A-SM-3NB3S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1292
BRD-K47574423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12448
PMC10322668-Table_7.xlsx-DE_genes_at_early_infection-List_of_de-regulated_genes_at_early_interaction_time_point_of_Dm28c_T_cruzi_THP1_infected_cells_From_Libisch_2020_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K58194737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3585
GSE171837_3_v_1_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08592
Perturb_3041_KO_Pgr_ERP140354	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
ventrolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.836008
Retrosplenial area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26647
Submedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19061
GTEX-R55D-0626-SM-3GAD5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921962
METRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8713
19658189-TableS5	GeneSigDB Published Gene Signatures	1.0	null
intermediate stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59887
Tricellular tight junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.504
congestive heart failure	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.676308
t56-vastus-lateralis_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.48353
GSE150055_0_v_1_melphalan_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.7333
TestisGermCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.979059
SMZ1	DepMap CRISPR Gene Dependency	1.0	4.29378
GTEX-VUSG-0726-SM-3GIK1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13263
PcPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16102
ZNF746	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17422
HOXD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82436
mantle zone of PcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53316
BLMH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68621
RAB5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48927
Perturb_6977_OE_ALOX12_SRP321065	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
QE-79-XO29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.409047
FBXO22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6793
abnormal postnatal growth	MPO Gene-Phenotype Associations	1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	1.94343
GSE151494_10_v_3_nrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PTPN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64201
GTEX-RNOR-2326-SM-2TF4I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.883682
IV	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.971307
Uterine Carcinosarcoma_UCS_TCGA-N7-A4Y5-01A-12R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.TP53.M_24H:E17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8046
layer 1 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23534
GTEX-X3Y1-0426-SM-3P5Z4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37286
EIF3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12489
EP300	ChEA Transcription Factor Targets	1.0	null
BRD-K12879624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12682
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.28115
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MEF2A_MEF2A	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8340-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43921
PITPNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79533
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09099
SETBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15779
GTEX-XXEK-1826-SM-4BRVC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903533
heart_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.51554
WDR35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33564
GTEX-NFK9-0926-SM-2HMJU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30563
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.2751
RUSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80749
GTEX-X261-0926-SM-3NMCY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08362
BRD-K33986892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17013
GTEX-OIZH-0726-SM-3NB1I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839147
BRD-K06994380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35432
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
FAM241B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33715
Cardiomyocyte_Heart_Human	CellMarker Gene-Cell Type Associations	1.0	null
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.84466
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A6L9-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RM2N-1926-SM-48FCU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.915658
DHPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57021
Anteromedial visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25281
H2AZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70368
parabigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44293
LB1047-RCC	GDSC Cell Line Gene Expression Profiles	-1.0	-1.77428
Adrenocortical carcinoma_ACC_TCGA-OR-A5JD-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cell Transformation, Neoplastic	CTD Gene-Disease Associations	1.0	1.21951
periventricular stratum of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.88575
Anteromedial visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43608
DA-81-VY50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.27345
SPRYD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43304
SPI1-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.75138
primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18961
GTEX-S4Z8-0526-SM-4AD4T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01193
CRCGN017_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.0011
BRD-K69659917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20551
GTEX-PWCY-0726-SM-48TCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.95391
CRCGN016_MCF10A.WT.HP_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.6173
Reticulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.058
SLC2A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47509
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28226
superficial stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36382
Intestine	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE157777_1_v_3_foxa3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TCF12/HEB-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ONCODG1	CCLE Cell Line Gene CNV Profiles	1.0	2.69414
magnocellular interstitial nucleus of the posterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5594
estradiol_mus musculus_gpl4134_gse23072	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FOXL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74386
GTEX-XYKS-0008-SM-4BRW6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0629
Brain Lower Grade Glioma_LGG_TCGA-DU-A76L-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BNC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93901
NDUFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0536
NPIPB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81265
Autoimmune disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.634
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.96449
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.897014
NDUFB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40595
GTEX-OXRL-0726-SM-3NM9A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06316
GSE92965_0_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Taenia tecta, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21053
nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
mantle zone of TG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44293
Esophagus	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.880145
GATA1	ENCODE Transcription Factor Targets	1.0	null
ATF3	ChEA Transcription Factor Targets	1.0	null
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IRAK2_knockout_76_GSE24264	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.22379
layer IIIu of area 35r	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13716
EMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53761
HT-144	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.54461
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33052
BRD-K39037393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12236
SHSY5Y	CCLE Cell Line Gene Expression Profiles	1.0	2.57883
PMC10592471-NIHMS1912771-supplement-2.xlsx-NR2F1-Ind-Upregulated_NR2F1	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM201	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67941
H3K36me3_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K13241788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25579
GTEX-WFG7-1626-SM-4LVMF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00919
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29622
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XV7Q-0826-SM-4BRV7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24648
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.96261
PDLIM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32466
GTEX-P4PP-0008-SM-48TDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74036
GTEX-X4EO-0526-SM-3P5Z3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882018
excretory gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.95549
GTEX-QLQ7-0526-SM-2I5G3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51239
ZBED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40533
gastric cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.414293
GFUS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30239
PCDH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01604
SCC-15	GDSC Cell Line Gene Expression Profiles	-1.0	-1.8684
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158197_6_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CHRDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24296
GTEX-VUSG-0126-SM-4KL1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08798
GSE100316_5_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SCRIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65989
COLO829	CCLE Cell Line Gene Expression Profiles	1.0	1.54136
GTEX-XUZC-0008-SM-4BOQG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.71719
GSE190316,GSE190324_1_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U3ZH-0326-SM-3DB7A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16612
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44815
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
PBX3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Atrioventricular node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.11
HOXD11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1692
JEG3	DepMap CRISPR Gene Dependency	1.0	2.03516
Trachea-cd4-positive, alpha-beta t cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0661869
BRD-K75369250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32959
PLCXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25405
GTEX-T2YK-0008-SM-4DM6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.22107
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.850537
MCF 10A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
BRD-K03923461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30545
GSPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98969
GTEX-XGQ4-0326-SM-4GIEE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65407
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
PRKAA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64492
TBC1D25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76973
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03044
BB-80-NH42_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.365892
LARP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45171
GSE231648_1_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8212786-DataSheet_4.xlsx-CESC-ZBED3_ZBED3	Rummagene Transcription Factor Associations 2026	1.0	null
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83607
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXK1_FOXK1	Rummagene Transcription Factor Associations 2026	1.0	null
Coronary artery smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.732
NAA60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49021
GTEX-RNOR-0526-SM-2TF4O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840974
k562	HPA Cell Line Gene Expression Profiles	-1.0	-1.42156
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_17_KD_HEK293-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BAG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0622
GTEX-X638-0326-SM-47JY1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854694
BRD-K30589514	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.13427
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.900816
NCI-H1944	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.29409
Inferior colliculus, central nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32338
RI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04297
GTEX-T5JC-0011-R2A-SM-32PLZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69656
BRD-K07361992	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84465
GTEX-QV44-0526-SM-2S1RE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50883
PDX1	JASPAR Predicted Transcription Factor Targets	1.0	null
PAX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7987
Gastrointestinal tract	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
LMO2	ChEA Transcription Factor Targets	1.0	null
pancreas_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.962699
MFSD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06264
GATA1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K08110534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51548
Prostate adenocarcinoma_PRAD_TCGA-HI-7169-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QMR6-0008-SM-447AV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850103
BRD-K27265817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72828
GTEX-SUCS-0326-SM-32PLL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8105
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.30452
t69-brown-adipose_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	3.35152
ventromedial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20094
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-Fay_Heat_LPStoThermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52076
brain_3b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.850001
GORAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04719
CNOT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82637
NCIH522	DepMap CRISPR Gene Dependency	1.0	2.21296
BRD-K92241728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70066
BRD-K50066702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06627
GTEX-P44H-0726-SM-48TBT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19144
Retrosplenial area, lateral agranular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.1413
GATA1-19941827-MEL-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
AD-16-HL96_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.228262
TIMM44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2015
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.7267
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
plant form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064344
TBX5	ChEA Transcription Factor Targets	1.0	null
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34499
skeletal muscle organ development	GO Biological Process Annotations 2025	1.0	null
layer 6b of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.82428
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7642
GTEX-S3XE-0426-SM-3K2AC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68105
BRD-K75130046	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84501
BRD-K11823863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24854
RPL35A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55306
PARD6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02729
GSE130401_6_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
r8 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34146
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1839
Tongue-capillary endothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0661869
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YN-11A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9008061-41467_2022_29733_MOESM4_ESM.xlsx-ERRg_SE_peaks-Gene_Name_ESRRG	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QMRM-0526-SM-2I5GA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23047
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38646
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7406-11A-01R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X585-3026-SM-46MWF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.87206
skeletal muscle organ development	GO Biological Process Annotations 2023	1.0	null
Left ventricular noncompaction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
u266	HPA Cell Line Gene Expression Profiles	1.0	1.27832
CHD1_02_187	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.59128
GTEX-NPJ8-0011-R1a-SM-33HCB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.975944
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.80847
GSE237040_2_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SPINDOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78715
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.858401
GSE193999,GSE194000_3_v_2_atf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
second-degree atrioventricular block	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.333
lateral spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.26032
BRD-K32401097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.28071
MRPL42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83589
CRCGN008_HEPG2_24H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.57105
ABL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20406
BRD-K63102090	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04464
18801183-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
BRD-K24166534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29333
GSE183335,GSE183351_3_v_0_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-SRF_SRF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WI4N-0726-SM-3TW93	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23603
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40564
GATA3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K82224868	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26773
BRD-K57382977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90538
Brain Lower Grade Glioma_LGG_TCGA-HT-A61B-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral terminal nucleus of the accessory optic tract, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.20335
Primary immunodeficiency disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.634
POU2F1-35413990-HUMAN-ARNEGCRPROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
MEGF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86926
ME-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.20511
Skeletal muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.329
GSE121824,GSE121826_0_v_6_scaf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
B4GALT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60826
SIN3A	ENCODE Transcription Factor Targets	1.0	null
UBA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75001
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MZ in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.826802
NFIC_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54699
BRD-K65913831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.04938
GTEX-WHWD-0326-SM-3LK6L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29082
IZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.842209
ES-I3 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.90415
SARAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.72197
UQCC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77618
STAT3-18555785-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ES3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COR-L26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.01603
FKBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46059
amygdalohippocampal transition zone, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.21628
BRD-K08489825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21675
Muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.95
xylazine-2132	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE195514_0_v_1_stk25_human	RummaGEO Gene Perturbation Signatures	1.0	null
NB1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.66866
BRD-K05250921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4047
heart ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.312232
ATP5PF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46193
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873287
Skeletal muscle fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.334
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SF-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K98891210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63059
SAMD4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59913
superficial layers of TG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.20878
EKVX	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.82566
GSE210377_0_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SPOPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.49971
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.960656
GSE216352,GSE216354_1_v_0_keap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
r7 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35786
stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.078346
Penis_Foreskin_Fibroblast_Primary_Cells_skin01	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.83548
Vasculature-epithelial cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0667499
trovafloxacin_homo sapiens_gpl96_gse9166	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-U3ZN-1426-SM-3DB87	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4964
BRD-K02866760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05644
BRD-K32063762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13979
MECOM-23826213-KASUMI-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:F24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1431
PMC8567138-Table_2.xlsx-Sheet1-IGFBP5_AND_IGFBP7_NOT_IGFBP3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
MDAPCA2B	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73081
Lung-smooth muscle cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0667499
BRD-K96384208	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23617
medial habenular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27128
GTEX-X4XX-0011-R2A-SM-3P623	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22878
smallintestine_4a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.969224
intermediate stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19587
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5690-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.92768
SYK_druginhibition_154_GSE34176	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.51058
FAM167B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50122
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34793
Fascia adherens	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.408
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.35616
GTEX-XBEW-1426-SM-4AT4J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06892
USP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51671
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.54233
KIF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85554
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QH-01A-21R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCN channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.204
NXPE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30472
PMC9589484-fcell-10-1022723.nxml--NETs_NOT_affecting_nuclear_size_upon_overexpression_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
RNF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52634
PRDM16_DEPLETION_GDS4021_460_mouse_WAT - white adipose tissue (stromal-vascular cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ELK1	JASPAR Predicted Transcription Factor Targets	1.0	null
ZNF212	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75776
Thymus-nk cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0667499
PMC3889689-elife01439s001.xls-RFX2_rnaseq_chip_DirectDE_final-GeneName_RFX2	Rummagene Transcription Factor Associations 2026	1.0	null
FTSJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06946
GTEX-OHPN-0008-SM-4E3HW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52391
LOXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43
Midbrain, behavioral state related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1396
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.98748
TCF12_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-0011-R10A-SM-2YUMO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34468
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8283158-mmc2.xlsx-TCF4_ChIP-symbol_TCF4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WEY5-0426-SM-3GIKT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41566
ATP5MC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73026
CALU-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.23445
BRD-K93752373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59646
RA-42-CM42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.420472
right atrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.867686
COX6A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24631
KPNRTBM1	CCLE Cell Line Gene Expression Profiles	1.0	1.52536
SPI1-22790984-ERYTHROLEUKEMIA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MOV10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80999
BRD-K63436213	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31984
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.882894
GSE120612_7_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.9294
RFX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55813
Lung adenocarcinoma_LUAD_TCGA-L9-A443-01A-12R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Aggressive Periodontitis	DisGeNET Gene-Disease Associations	1.0	null
HCC2218	CCLE Cell Line Gene CNV Profiles	-1.0	-1.93087
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GK-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-Row_names_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JB-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
alimentary canal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.919487
PMC11389323-12915_2024_1993_MOESM2_ESM.pdf-13-PAX7_PAX7	Rummagene Transcription Factor Associations 2026	1.0	null
gallbladder	HPA Tissue Protein Expression Profiles	1.0	1.36699
GSE234043_3_v_1_abcb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POU3F4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85117
TMTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07501
PTAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5048
CPNE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.786
EP300-21415370-HL-1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ACSS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99309
GTEX-RWS6-0326-SM-2XCAP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64749
PRAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4892
Lung squamous cell carcinoma_LUSC_TCGA-77-A5GH-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8267
abnormal heart morphology	MPO Gene-Phenotype Associations	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ATF3_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K25312635	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14329
PMC10592471-NIHMS1912771-supplement-7.xlsx-D-HEp3-Enh_vs_AA-up_genes-AA_up_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
sarcolemma	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.259109
GTEX-WRHU-1026-SM-4E3ID	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2415
Fatty Liver	CTD Gene-Disease Associations	1.0	1.31867
decreased body size	MPO Gene-Phenotype Associations	1.0	null
GPR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64885
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05771
EB1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.29166
PMC4595011-pgen.1005555.s001.xlsx-BPTF_UP-regulated-Gene_name_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.932258
GATA2	ChEA Transcription Factor Targets	1.0	null
BRD-K25127909	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20908
RTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60959
GSE149264,GSE149267_4_v_5_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UJMC-0008-SM-4IHKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4168
GSE82104,GSE82299_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE176305_0_v_3_rotenone_human	RummaGEO Drug Perturbation Signatures	1.0	null
MDA-MB-231	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31612
PMC7846764-41598_2021_81773_MOESM3_ESM.xlsx-b-Heart_AA_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2083
medial portion of the shell	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.40956
CRCGN013_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19173
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
WSU-DLCL2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.46429
EBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46144
NCI-H2085	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55276
SU-DHL-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01542
vincristine_rattus norvegicus_gpl1355_gse19290	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Myotome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.64
ACSL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61999
GSE111035,GSE111040_8_v_5_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
G124	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863257
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.58772
CDC37L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68259
BRD-K20724649	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01394
Lung adenocarcinoma_LUAD_TCGA-55-6981-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K78009480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13876
BRD-K31372389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92493
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1012
HPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69645
hacat	HPA Cell Line Gene Expression Profiles	-1.0	-1.11442
GSE60217_1_v_2_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-V1D1-0008-SM-4JBIJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.25293
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-5847-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61593
SCAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53352
GTEX-QESD-0526-SM-2I5G5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87065
Prostate adenocarcinoma_PRAD_TCGA-TK-A8OK-01A-22R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MITF	ChEA Transcription Factor Targets	1.0	null
Blood-cd4-positive, alpha-beta memory t cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0667499
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PSN1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.93649
GSE212299_2_v_1_abi3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SETD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.58792
PMC10165318-MCO2-4-e258-s001.docx-0-Down_PRP3-KD_vs_PRP3-wt_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7032
ZNF345	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83371
superior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.26486
WFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25867
sinus bradycardia	MGI Mouse Phenotype Associations 2023	1.0	null
PMC11426526-ppat.1012555.s011.xlsx-DEG_MDDC_Jurkat_LPS_vs_MDDC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE201042_2_v_1_ptpmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K54604127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4028
BRD-K08829593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29738
PF-00539758-00-6379	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Holt-Oram syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.197
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.878473
Prostate adenocarcinoma_PRAD_TCGA-KC-A4BR-01A-32R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Superior olivary complex, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50912
GTEX-X8HC-1626-SM-46MWE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22942
GTEX-QEL4-1226-SM-447A4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0323
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-UPK5-1426-SM-4JBHH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30199
TM31	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
Integumentary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.634
Central amygdalar nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42543
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2056
ZNF217	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66657
HELZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34404
Muscle-endothelial cell of artery	Tabula Sapiens Gene-Cell Associations	1.0	-0.065061
Cellular anatomical entity	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
MYOD1_myocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
pericardium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.0775
BRD-K02024244	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18056
RBMY1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.091
estradiol-365	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
biological regulation	GO Biological Process Annotations 2015	1.0	null
Spindle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.912
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3WC-11A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K64860451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73687
GSE130401_4_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
anterior (rostral) cingulate (medial prefrontal) cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.901968
BRD-K83994491	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31574
GTEX-Q734-0426-SM-48TZX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15856
Lung squamous cell carcinoma_LUSC_TCGA-66-2755-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K36me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cardiac tube	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.177
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5440-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
16643655-306GenesList	GeneSigDB Published Gene Signatures	1.0	null
KRTAP13-4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09157
GTEX-WEY5-1026-SM-4LMK9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03294
MECOM-23826213-KASUMI-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6972-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WNK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26365
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.73554
intermediate part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44595
ELK4	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K73872184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75659
H3K4me1_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K22915992	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62283
Lung squamous cell carcinoma_LUSC_TCGA-85-7950-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K77905217	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17193
CDK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58298
JVM3	CCLE Cell Line Gene Expression Profiles	1.0	2.15546
posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.865928
dorsolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08805
TP53-23651856-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Postsynaptic cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.57
PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_3_SED-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
colonrectum_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.969579
HCC95	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32925
RVH421SKINFV1	DepMap CRISPR Gene Dependency	1.0	2.13218
TOB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3018
PHF21B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20959
PMC7334247-12031_2020_1490_MOESM2_ESM.xls-THAP1_S21T_vs_wt-Gene_Symbol_THAP1	Rummagene Transcription Factor Associations 2026	1.0	null
RCC-JW	COSMIC Cell Line Gene Mutation Profiles	1.0	null
C1QL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2152
GSE152055_0_v_1_mpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NR5A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67849
GINS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22724
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8975
TXNDC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83454
regulation of heart contraction	GO Biological Process Annotations 2015	1.0	null
HOXD12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.252
NCI-H1436	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-R55G-0008-SM-48FEX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79484
CRCGN015_HEPG2_48H:D15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09888
HAPLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96248
ventral juxtacommissural pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43051
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.589219
BCLAF1_02_142	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.14296
NB12	GDSC Cell Line Gene Expression Profiles	1.0	2.80385
GSE180800,GSE180801_0_v_5_tex10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE130401_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83727
heart	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.732677
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18271
H2BC26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62887
TSR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8845
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8243
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WH7G-0826-SM-4LVMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.881516
SNW1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33929
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_1_TRC-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XYKS-2426-SM-4AT43	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859476
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KA-75-LP02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.855577
DBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3495
posteroventral (inferior) parietal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07801
AD-99-SN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.03175
GTEX-O5YW-0008-SM-4E3IE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67429
GSE165939_2_v_1_poldip2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QEL4-1426-SM-447AC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36542
EB2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.33395
circulatory system development	GO Biological Process Annotations 2025	1.0	null
Myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.955
GALR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00574
TNFSF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81752
ELOA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96876
NCI-H740	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF683	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13062
BFTC-909	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863257
heart development	GO Biological Process Annotations 2025	1.0	null
GTEX-XBED-0526-SM-47JY3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67689
Striated muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.857
PMC9691391-7945884.f3.pdf-0-ENSG00000008196_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
Chronic Periodontitis	DisGeNET Gene-Disease Associations	1.0	null
IMR-5	GDSC Cell Line Gene Expression Profiles	1.0	1.51831
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08325
GTEX-X4XX-0011-R10B-SM-46MWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47509
hippocampus (hippocampal formation)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.980619
UBIAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95626
BACE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45814
ATP5IF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91593
GTEX-S32W-1026-SM-4AD5W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855055
BRD-K41423946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.31871
GTEX-OHPM-0326-SM-33HCA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35057
GTEX-OIZF-1526-SM-3MJGY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57477
Brain - Substantia nigra	GTEx Tissue Gene Expression Profiles 2023	1.0	4.10673
GSE68156_3_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.853131
CDK5RAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78478
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.946785
adenyl ribonucleotide binding	GO Molecular Function Annotations 2023	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4971-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF516	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27076
Urinary bladder	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NFE2L2_02_174	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.67243
EP300-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
cell development	GO Biological Process Annotations 2015	1.0	null
Adrenergic signaling in cardiomyocytes	KEGG Pathways 2026	1.0	null
EBNA1-20929547-CHIP-SEQ-RAJI-CELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K24877937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52296
GSE158715_2_v_4_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039605
BRD-K08431704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26109
GSE131798,GSE131804_1_v_0_igf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
T-tubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.808
BRD-K21996934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68884
CRCGN016_MCF10A.TP53.M_24H:F11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21049
GRTP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93477
CI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.45824
layer III of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25221
valdecoxib-6378	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XBED-1726-SM-47JYO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878043
GSU	CCLE Cell Line Gene CNV Profiles	1.0	1.99486
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.838509
inner CP in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.895075
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K00363054	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20315
NCIH1876	CCLE Cell Line Gene CNV Profiles	1.0	1.56086
CTCF_MCF-7_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XV7Q-0726-SM-4BRV6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23146
organic cyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
Sarcoma_SARC_TCGA-DX-A6B9-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SHMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.235
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.634
GTEX-NPJ8-1526-SM-2D7VU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935123
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.243414
GTEX-XQ8I-1626-SM-4BOOI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996394
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.862529
hsa-miR-224	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
QE-79-XO29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.21049
GTEX-R55E-1026-SM-2TC5S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44477
BRD-K35943892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.6987
GATAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97155
ELF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8228
AM-38	COSMIC Cell Line Gene Mutation Profiles	1.0	null
motor nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.963117
GSE174498,GSE174500_0_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC3923219-mmc2.xls-Table_S1-Table_S1_Differential_Gene_Expression_in_GFP-PRDM1_transduced_H9_hESCs_PRDM1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NL4W-0011-R6a-SM-2I3GA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.987008
CRCGN017_MCF10A.WT.HP_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3857
intermediate part of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05693
PUF60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20379
BTG2	Pathway Commons Protein-Protein Interactions	1.0	null
S117	DepMap CRISPR Gene Dependency	1.0	13.57
Lung adenocarcinoma_LUAD_TCGA-50-5049-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
spanning component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.200328
GTEX-SE5C-0626-SM-2XCDV	GTEx Tissue Sample Gene Expression Profiles	1.0	2.17545
GEMIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67732
biological_process	GO Biological Process Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6347-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCVADR RES	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.885429
primary motor-sensory cortex (samples)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1176
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18566
GTEX-WHSE-0011-R1A-SM-3P5ZK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2052
SRD5A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0587
intermediate part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.76065
SK-N-AS	GDSC Cell Line Gene Expression Profiles	1.0	2.08975
DMRT1-23473982-TESTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE58724_3_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
seedling	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069389
BRD-K40558736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05854
BRD-K55578148	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65264
placenta	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.78446
Uterine leiomyoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.081
inferolateral temporal cortex (area TEv, area 20)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.64802
ENTPD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08156
KCTD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27519
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K63401195	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03062
Perturb_2948_KD_Hnrnpk_DRP004738	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.21058
hydroxyamphetamine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00088
WB-48-EF24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.549017
USF1_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.719524
BRD-K60806315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.86891
GSE255432_6_v_2_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-NPJ7-0011-R1a-SM-3GACT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7321
17404395-TableS1d	GeneSigDB Published Gene Signatures	1.0	null
GSE149123,GSE149128_1_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Congenital heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.471
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.39754
Perturb_4708_KD_Dnmt3b_SRP069225	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	16.2862
Cardiac Purkinje fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.231
SNB19	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52277
TUHR10TKB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60109
BRD-K30566330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28449
NCIH1648	CCLE Cell Line Gene CNV Profiles	1.0	1.53393
TCF7L2-21901280-H4IIE-RAT	ChEA Transcription Factor Targets 2022	1.0	null
Primary somatosensory area, mouth, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33448
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TMSB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.94139
Lung squamous cell carcinoma_LUSC_TCGA-85-7710-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QDVJ-0826-SM-48U1S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841254
ZNF518A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.01442
TMBIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82525
BRD-K26233698	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5143
NCIH526	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47405
GSE113734_1_v_0_qprt_human	RummaGEO Gene Perturbation Signatures	1.0	null
Excretory gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TEAD4	ENCODE Transcription Factor Targets	1.0	null
ATP5PD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08071
C80	DepMap CRISPR Gene Dependency	1.0	7.75923
BRD-K20185935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36233
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MR-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K05969019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2034
basal ventral medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.830006
GATA4-21415370-HL-1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BF-02-AC35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.721164
Roberts syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.238
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.82485
Subiculum, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.01823
GSE157904_0_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.868863
GTEX-S32W-0626-SM-2XCBG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43336
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4353-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WDR82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56877
Prostate adenocarcinoma_PRAD_TCGA-HC-7745-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW 780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.39233
Pulmonary vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.727
GSE149124,GSE149128_2_v_1_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.2553
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.949025
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.24983
PMC10082046-41467_2023_37049_MOESM6_ESM.xlsx-Sheet1-Supplementary_Data_3_Genes_downregulated_in_ASPS-KY_cells_by_ASPSCR1-TFE3_knockdown_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF536	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21859
intermediate stratum of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.04244
IA-LM	GDSC Cell Line Gene Expression Profiles	-1.0	-2.07485
LCLC-97TM1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.73049
PPP5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29339
GTEX-R53T-0326-SM-48FEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55797
HBQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09713
THAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70616
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.73302
rostral (anterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08765
GTEX-XUZC-1226-SM-4BRVJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83485
Prostate adenocarcinoma_PRAD_TCGA-G9-6384-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XL-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCDC69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99977
BROX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52631
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_HEPG2_48H:E10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2319
JcP contribution to LTL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57125
LAMC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21161
GTEX-P4PP-0326-SM-33HC4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19094
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE186440,GSE186443_1_v_7_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
MCEE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.41933
HOXD10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7005
GSE229102_1_v_0_nr2f6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.32076
BRD-K77401804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4316
AKT1_activemutant_9_GDS2304	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.94907
BRD-K31870622	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00713
AGGF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74213
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.8245
layer 5 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06542
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.37238
GATA4	ChEA Transcription Factor Targets	1.0	null
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.94797
FUT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66544
MAP1LC3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4279
Brain Lower Grade Glioma_LGG_TCGA-CS-6186-01A-12R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
icSARA deltaORF6_60Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.41514
PTPRZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58808
PMC11428309-12920_2024_2011_MOESM1_ESM.pdf-26-PITX1_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
ventrolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25911
ZDHHC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96565
HEC1B	CCLE Cell Line Gene CNV Profiles	1.0	1.43988
Lung adenocarcinoma_LUAD_TCGA-NJ-A4YQ-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.04314
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KE97	CCLE Cell Line Gene Expression Profiles	1.0	1.79072
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31612
BRD-K26045715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29126
GTEX-RU1J-1326-SM-46MUL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899916
GFY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88334
Rectum adenocarcinoma_READ_TCGA-AG-3732-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cAMP binding	GO Molecular Function Annotations 2023	1.0	null
EP300_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCDC51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60792
BRD-K27406233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1883
RAD54L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30055
Pancreatic adenocarcinoma_PAAD_TCGA-3E-AAAZ-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SIU8-0826-SM-2XCDQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2497
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A68C-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE100102_0_v_5_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DJ-1_KD_GDS3750_373_human_SH-SY5Y	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ZNF35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.9012
GTEX-QXCU-0008-SM-48FCH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95645
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.871392
rostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.43298
SDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29038
U2904	DepMap CRISPR Gene Dependency	1.0	3.45638
BACH1-22875853-CHIP-PCR-HELA-AND-SCP4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
stomach	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.101469
HACD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56466
BRD-K77250455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39673
GSE195559_8_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE221633_3_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_11_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7275
Myenteric plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.731
GSE181966_5_v_3_has2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K44641066	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63973
GSE58724_1_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TRIM33_KD_GDS4071_449_human_HMEC-TR mammary epithelial cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K9ac_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5717
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12568
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911498
cSARS Bat SRBD_54Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.53691
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879978
Perturb_13649_OE_miR27_SRP067253	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.74016
GBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22331
RXRA_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
octreotide	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29221
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1891
Perturb_9797_OE_YAP1_SRP132362	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
mantle zone of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44595
KBTBD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23411
skeletalmuscle	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.868511
CRCGN015_MCF10A_48H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3808
Perturb_16117_KO_Mfn1_SRP189355	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.1951
Chronic atrial and intestinal dysrhythmia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.695
BRD-M34385771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03036
GTEX-UPK5-1226-SM-4IHL8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.972679
VPS29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47563
GTEX-WL46-0726-SM-3LK5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20665
cerebellar cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.24901
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.85124
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.24503
Lung adenocarcinoma_LUAD_TCGA-93-A4JQ-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10311050-mmc2.pdf-46-LMX1B_LMX1B	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34031
NIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01513
Sick sinus syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.447
OVOL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42741
AB-18-YN11_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.269888
MRS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47559
RPS24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02775
CRCGN015_MCF10A_48H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14305
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H8-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-FB-A7DR-01A-21R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K79877849	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09492
GTEX-X5EB-1026-SM-46MVU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900282
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K24689407	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.57568
GTEX-O5YT-0008-SM-4E3IQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.14253
ZNF275	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8445
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GT-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
zardaverine-4209	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Atrioventricular block	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.573
CGGBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71848
ETS1	ENCODE Transcription Factor Targets	1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_y_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE174498,GSE174500_0_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K16633334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02983
amygdaloid complex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.923882
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04278
UBE3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27857
KNS-62	GDSC Cell Line Gene Expression Profiles	-1.0	-1.68471
Anteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79573
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.67748
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Entorhinal area, lateral part, layer 2b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42403
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
USF1	ENCODE Transcription Factor Targets	1.0	null
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.966552
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.072
STAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16331
posteroventral (inferior) parietal cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-3.55945
Heart Defects, Congenital	CTD Gene-Disease Associations	1.0	1.07447
Prostate adenocarcinoma_PRAD_TCGA-EJ-7797-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-V955-1026-SM-4JBHO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932407
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00561
CRCGN012_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.50545
HL-60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.94791
Lung adenocarcinoma_LUAD_TCGA-55-7574-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HTR1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1147
CRCGN017_MCF10A.WT.HP_24H:H12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.30985
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.834285
ELP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69778
LY-294002-361	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
COPS9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8171
IZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.848073
DANG	CCLE Cell Line Gene CNV Profiles	1.0	1.52387
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8344-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Retrosplenial area, lateral agranular part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01104
INPP5K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15937
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.9789
GTEX-U4B1-1026-SM-4DXT1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.922143
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SE5C-1026-SM-4BRUG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991517
HCC202	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-O5YV-1026-SM-3LK72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19667
GSE143743_0_v_2_c9orf72_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7846764-41598_2021_81773_MOESM2_ESM.xlsx-b-Heart_AA_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66925
periventricular stratum of ITTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07169
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7059
Right_Atrium	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.39802
GTEX-POYW-1326-SM-48TCG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28704
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.6569
PMC11187145-41525_2024_418_MOESM1_ESM.pdf-22-TP73-AS1_TP73	Rummagene Transcription Factor Associations 2026	1.0	null
RAB1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60581
Inflammation	CTD Gene-Disease Associations	1.0	1.66167
TFRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28262
GTEX-OXRK-1826-SM-2HMJE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859631
GSE149123,GSE149128_2_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF_Q1_vs_Q4-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.20436
BICR18	CCLE Cell Line Gene CNV Profiles	1.0	1.684
Caveola	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.44
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TD-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33137
NANOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10087
BRD-K21732483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99063
SP in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.913944
Muscle tendon junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.21
NRARP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65155
NCIH2196	CCLE Cell Line Gene CNV Profiles	1.0	1.7171
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.77529
STAT3_01_168	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59712
GTEX-XXEK-0926-SM-4BRWH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91221
Tetralogy of Fallot	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.527
MDA-MB-435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.99829
LA-42-ER00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.240698
PMC8567280-EMBR-22-e53014-s007.xlsx-Sheet1-Nearest_genes_to_BAZ2A-bound_C2-Enhancers_BAZ2A	Rummagene Transcription Factor Associations 2026	1.0	null
Neoplasms	CTD Gene-Disease Associations	1.0	1.32607
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863257
posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.41487
GTEX-XUJ4-0626-SM-4BOOO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71925
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.827017
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
slow postnatal weight gain	MPO Gene-Phenotype Associations	1.0	null
Congenital myopathy 1A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.109
496100279_TCx_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.14362
DU 145	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10893
PBXIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.02043
GTEX-WHWD-0426-SM-3LK83	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2746
GSE182770,GSE182784_0_v_1_chd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
HOXC11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9017
REM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17438
GTEX-NPJ7-0008-SM-4E3JS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.79457
SUM229PE	DepMap CRISPR Gene Dependency	1.0	8.74698
GTEX-NFK9-2026-SM-3LK5K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914014
GTEX-XUW1-1926-SM-4BOP1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992923
PTK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38169
ACSBG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79752
GTEX-V955-1726-SM-4JBHF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.083
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.839678
Large_Intestine-intestinal tuft cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0667499
CRCGN016_MCF10A.TP53.M_24H:M22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.35959
NDUFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27036
RHOH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19432
GTEX-SN8G-0326-SM-32PLG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848749
anatomical structure development	GO Biological Process Annotations 2015	1.0	null
12917485-Table6	GeneSigDB Published Gene Signatures	1.0	null
A-Netherlands-602-2009(H1N1)_18Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.58602
parahippocampal gyrus, left, bank of the cos	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.843859
Infertility, Female	CTD Gene-Disease Associations	1.0	1.35127
abnormal heartbeat	MPO Gene-Phenotype Associations	1.0	null
lateral part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22335
ATF3-23680149-GBM1-GSC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
THEM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88385
PPP4R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90622
GTEX-OXRL-0326-SM-2I3F2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72401
H3K27me3_CH12.LX_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K63008302	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68615
GCLC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54541
cardiovascular system phenotype	MPO Gene-Phenotype Associations	1.0	null
decreased total tissue mass	MPO Gene-Phenotype Associations	1.0	null
MSANTD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83297
GTEX-SJXC-0008-SM-4DM7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21316
BRD-K59155687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0454
Kidney Chromophobe_KICH_TCGA-KM-8476-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_18499_KO_TWIST1_SRP121466	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
FOXD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0189
NCI-H2342	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RPL22L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77984
molecular_function	GO Molecular Function Annotations 2015	1.0	null
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40354
PRDM14-20953172-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
COX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08691
GTEX-W5WG-1926-SM-4KKZK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956794
primary auditory cortex (core)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.901374
GTEX-R55D-1526-SM-48FEJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05608
PLTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94477
GSE110708_1_v_3_adar_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216538_5_v_6_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WL46-0926-SM-3LK7T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34424
Brain Lower Grade Glioma_LGG_TCGA-VW-A7QS-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CF-24-KQ98_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.238047
GTEX-X4XX-0626-SM-3NMC1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950086
C4I	DepMap CRISPR Gene Dependency	1.0	2.37505
CEBPB-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
skeletal muscle tissue development	GO Biological Process Annotations 2023	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JB-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate portion of DFC (area 9/46)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.99828
GSE68156_3_v_4_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NRL_Deficiency_GDS1693_236_mouse_Photoreceptors cells of retinas at P2	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
KE-41-JG66_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.244939
496100402_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.83038
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.26578
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20R-11A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XPT6-0008-SM-4B64Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.01909
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.82147
RCOR1	ENCODE Transcription Factor Targets	1.0	null
GTEX-R3RS-0008-SM-48FF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10434
BRD-K83935370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84119
NA-30-HS87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.3613
YY1	ENCODE Transcription Factor Targets	1.0	null
ADNP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46339
Retrosplenial area, lateral agranular part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.13826
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1716
Brugada syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.376
HOXB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87114
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.79951
Left_Ventricle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.88638
CORL23	CCLE Cell Line Gene CNV Profiles	1.0	1.42267
PMC10592471-NIHMS1912771-supplement-4.xlsx-D-HEP3_UP_AA_UP-AA_UP_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
germ layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.310421
Cardiac muscle fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.864
GSE141726,GSE141733_1_v_0_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Skin-cell of skeletal muscle	Tabula Sapiens Gene-Cell Associations	1.0	-0.0667499
GTEX-P4PQ-0008-SM-48TDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10008
GSE135030_11_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12022
cingulate gyrus, retrosplenial part, left, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.960922
TBX5-21415370-HL-1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
DLST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69802
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39233
Prostate-mast cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0667499
ventrolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24657
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.4422
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RAB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92351
medial superior olive	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.69614
N4BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34813
GSE246195,GSE246305_4_v_5_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
orbital frontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29267
BRD-K94751306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20152
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863257
GSE122215,GSE122217_0_v_1_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
heart	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
NCIH1105	CCLE Cell Line Gene CNV Profiles	1.0	2.33385
AC-30-XU83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.207355
ventrolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.937107
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.958419
inferior olive, principal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.908537
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18276
TCF3_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsofrontal pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.53771
TLE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75349
UF-27-HS98_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.217538
VASH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57152
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10893
abnormal sinoatrial node conduction	MPO Gene-Phenotype Associations	1.0	null
periventricular stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04231
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.68137
BRD-K56384721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28758
AP3M2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41298
lateral trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74909
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23461
cAMP signaling pathway	KEGG Pathways 2026	1.0	null
muscle tissue development	GO Biological Process Annotations 2023	1.0	null
GTEX-TSE9-0011-R1A-SM-3DB7E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09453
BRD-K57830670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6068
GSE237040_6_v_5_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Phospholamban complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.206
FXYD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90273
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26482
SLC22A31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08684
NCOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68897
CRCGN015_MCF10A_48H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.99174
ZBTB20_Deficiency_GDS3718_517_mouse_Developing hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063023
FOXQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82069
REST_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACACB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36165
Sarcoma_SARC_TCGA-IW-A3M6-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-SNU-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053547
GFM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96137
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
MPZL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8392
RGS14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97119
BRD-K07794261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19329
GOLGA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67032
CNPY4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38773
FGF21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23691
PNISR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73249
CCAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66246
496100659_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.18926
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863257
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042613
pralidoxime-6443	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BL41	CCLE Cell Line Gene CNV Profiles	-1.0	-1.87426
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB1-F2del_24Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.32443
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A77P-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03838
GTEX-SNMC-0126-SM-2XCFO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41336
BRD-K83487481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30646
BEND5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51535
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A3JJ-11A-12R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
adenyl ribonucleotide binding	GO Molecular Function Annotations 2025	1.0	null
NCI-H2126	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.11082
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.967203
sarcolemma	GO Cellular Component Annotations 2025	1.0	null
NCI-H460	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0046
abnormal cardiovascular system morphology	MPO Gene-Phenotype Associations	1.0	null
GTEX-O5YW-1426-SM-3MJHF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8328
GTEX-T5JW-1826-SM-3GAE1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00219
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A7U6-01A-12R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K59185421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36476
GTEX-XUJ4-0526-SM-4BOON	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65743
BRD-K22715231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.07906
Pericardium disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.248
GSE215461_0_v_1_topotecan_human	RummaGEO Drug Perturbation Signatures	1.0	null
Muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.136
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6837
periventricular stratum of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00965
SNX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99612
CMC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07435
KLHL42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98863
WNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53765
t60-adrenal_male_1w	MoTrPAC Rat Endurance Exercise Training	1.0	3.31085
GSE231648_1_v_5_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.1889
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1969
GSTO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87494
olfactory part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17859
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.91758
KMS18	CCLE Cell Line Gene Expression Profiles	1.0	1.43154
GTEX-OIZG-1126-SM-2HMIU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19358
GSE218879_1_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-2689-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K17765399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3861
BRD-K06719105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68548
GTEX-OHPL-0326-SM-33HC8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50244
OCI-AML5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.53007
primary auditory cortex (core)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01139
DDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66356
TIA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42744
dactinomycin_homo sapiens_gpl7172_gse12459	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ST6GAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79533
GTEX-XXEK-0008-SM-4BRW7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41657
TAL1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Gene_Name_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072505
GTEX-QDVJ-0726-SM-48U1W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44527
primary auditory cortex (core)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08805
Nucleus of the posterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.77722
merbromin-3700	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
vitamin c_homo sapiens_gpl570_gse11919	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AP-4	MotifMap Predicted Transcription Factor Targets	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33419
Brain Lower Grade Glioma_LGG_TCGA-P5-A72U-01A-31R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K30632097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.25618
PMC12621392-12864_2025_12212_MOESM2_ESM.xlsx-GSF-S_48h_1-Unnamed_0_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
PTS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96516
BRD-K13502206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13072
BRD-K26543702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33081
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.11406
Prostate Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
BRD-K87167435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21324
intermediate stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33187
atrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.708041
cardiac muscle cell development	GO Biological Process Annotations 2015	1.0	null
TAF15_02_163	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.66626
MAP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92043
ACTR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02221
FZD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75645
PMC2263127-pone.0001816.s002.xls-Terms_with_Genes_E2F3_up_Bild-Title_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF696	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.339
TEAD4_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.95262
NCIH146	CCLE Cell Line Gene CNV Profiles	1.0	1.62688
mesothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.511384
colon	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.31354
TNFRSF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41798
somite	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.871061
GSE100102_2_v_5_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7882-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IA-76-ZU47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.382017
medial superior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39563
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90086
ITK_knockout_242_GSE12465	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.02867
GTEX-RVPU-0008-SM-3NM8B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72949
PIGH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60558
BRD-K64132098	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04673
cardiac pacemaker cell development	GO Biological Process Annotations 2015	1.0	null
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
ELP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58008
Lung adenocarcinoma_LUAD_TCGA-50-8459-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPK-0326-SM-2HMJO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33546
GTEX-OHPM-0008-SM-4E3IP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.94365
PTK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95954
GYS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85799
GSE157282_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
gastric cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.419623
BRD-K85917058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16455
GSE146687_2_v_5_eribulin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8195
anterior olfactory area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17195
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2J9-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
stomach	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K64353626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44636
SNU201	DepMap CRISPR Gene Dependency	1.0	2.24868
superficial stratum of TG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.12045
growth/size/body phenotype	MPO Gene-Phenotype Associations	1.0	null
GTEX-RTLS-0826-SM-2TF5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26397
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	3.50683
EP300_SK-N-SH_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBEC-1226-SM-4AT65	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75672
Cyclic nucleotide-binding-like	InterPro Predicted Protein Domain Annotations	1.0	null
TXNDC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01372
ventrolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.970656
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.2187
CRCGN014_HEPG2_3H:E15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.00536
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.77701
Anteromedial visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06979
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPATC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44618
superficial layers of olfactory entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.67236
Allantois	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.916
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.871056
PAK1IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97385
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17399
BCL11B_KO_GDS3178_296_mouse_striatum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
496100284_FWM_probable Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.61928
Fetal Brain Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.35044
rectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.219707
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2238
EIF4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30403
ARFGAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1525
SHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22173
HS 766T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.963765
Weight Gain	CTD Gene-Disease Associations	1.0	1.37018
colon	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Sarcoma_SARC_TCGA-WK-A8XY-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
X	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.900767
VDAC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.83169
r2 part of prepontine raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34985
Lung squamous cell carcinoma_LUSC_TCGA-37-4129-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM265	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58542
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1449
abnormal heart right atrium morphology	MPO Gene-Phenotype Associations	1.0	null
ZKSCAN1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFON-0326-SM-3GIKX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6548
BRD-K20160406	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17548
C2orf81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11998
subgranular zone of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.90641
diclazuril	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96424
LAN-6	GDSC Cell Line Gene Expression Profiles	1.0	2.08439
GTEX-WFJO-0726-SM-4LVM8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.979439
BRD-K99856384	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8479
TAL1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44758
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.63316
hsa-miR-1294	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Intercalated disc	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.185
urinarybladder_5b	HPA Tissue Sample Gene Expression Profiles	1.0	1.01846
PPARalpha_OE_GDS2289_244_mouse_Skeletal muscles	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10893
SHSYSY+RA	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.36856
levocabastine-hcl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0013
plant embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069389
GATA1-19941827-MEL-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NF-21-HQ00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.312725
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17557
OCIM2	DepMap CRISPR Gene Dependency	1.0	2.55611
PMC6420765-12864_2019_5550_MOESM5_ESM.xlsx-D4_vs_D9-Unnamed_2_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
Periventricular hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73713
GTEX-WZTO-1326-SM-3NM8X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63009
CRIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19662
GTEX-W5WG-1526-SM-4LMIG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896926
RASSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02015
AP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
GATA2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
imatinib-366	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Sarcoma_SARC_TCGA-DX-A3UB-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K13674694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00271
KMH2	CCLE Cell Line Gene CNV Profiles	-1.0	-2.13479
AGFG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5213
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12696
GTEX-S3XE-1126-SM-4AD4N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90913
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
ABCB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60441
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.63072
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51N-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HLA-A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22705
GTEX-XUJ4-0926-SM-4BOPA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07338
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.19
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5887-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPL36AL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14119
mantle zone of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22566
TP73	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7611
ST6GALNAC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6251
GSE183316,GSE183317_4_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PSME4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44241
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31612
kidney	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K02329600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42774
GSE179036_1_v_0_trim24_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.46874
BRD-K36537572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17569
UBQLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80959
GTEX-XLM4-2026-SM-4AT4X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44335
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YJ-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-K1-A3PO-11A-12R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HL-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.724
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GE-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Colorectum	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE180200,GSE180201_15_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.845407
C5orf24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33459
GPR50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73701
NECTIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06477
BRD-K48899005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49581
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
HDAC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86667
Infralimbic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23813
H3K36me3_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Stomach disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.164
ZNF681	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25048
Lung Diseases	CTD Gene-Disease Associations	1.0	1.3036
EZH2	ENCODE Transcription Factor Targets	1.0	null
abnormal body weight	MPO Gene-Phenotype Associations	1.0	null
vascular bundle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.142266
CPXCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95052
HES4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66291
GSE130401_4_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TMEM43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28682
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44Q-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K46658587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03212
JVM2	CCLE Cell Line Gene Expression Profiles	1.0	1.97133
GTEX-QVUS-0226-SM-3GIJY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909114
anterior cortical nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2628
icSARS CoV_7Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.94913
NOL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52558
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7781
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3349-01A-01R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2038
Perturb_5031_KO_4930500J02Rik_SRP072189	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.88344
8305C	CCLE Cell Line Gene Expression Profiles	-1.0	-2.0413
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NF-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.663
GTEX-XPT6-0226-SM-4B65L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07936
GRANTA-519	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.978719
PGR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1478
Stomach	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
AP1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85244
ZRANB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39771
paracentral lobule, posterior part, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.03919
GTEX-XQ3S-0526-SM-4BOQA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31632
cardiovascular system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MH-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21869
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cardiomyocyte_Embryo_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
BRD-K73849129	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04597
GTEX-S4Z8-0008-SM-33HAZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4184
BRD-K23442578	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.14201
CRCGN015_HEPG2_48H:F04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.55128
anion binding	GO Molecular Function Annotations 2025	1.0	null
HDGFL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24286
PLK1_druginhibition_181_GSE46856	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.60089
496100467_FWM_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.04044
BRD-K13226037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20223
primary auditory cortex (core)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02789
layer 1 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31917
GSE160083,GSE160084_1_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE183316,GSE183317_1_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TFDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59695
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.973834
CL11	DepMap CRISPR Gene Dependency	1.0	7.79426
PMC4957230__F4	PFOCR Pathway Figure Associations 2023	1.0	null
GTEX-RVPV-0008-SM-47JYW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.57339
BRD-K19085288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53896
Perturb_3330_KO_miR27_SRP092642	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	14.9909
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.2112
GSE150055_0_v_2_melphalan_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cerebellar cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.72204
rostral group of intralaminar nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.893176
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.960656
CAL-12T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-N7MS-0826-SM-2HML4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29799
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885781
GTEX-O5YT-0326-SM-32PKA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94964
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.39888
GSE210682_2_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.40471
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863257
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-1.06705
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.216
SERHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7542
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.945019
layer 6a of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51966
DGCR6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84243
ChIP_ASH2L_23239880	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843323
BRD-K67626097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17372
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.69224
TBCEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85879
heart_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.81369
GTEX-VJYA-0726-SM-4KL1T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86692
UBXN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06424
ZNF284	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96833
ASH2L-23239880-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K11004561	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06114
ventrolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21808
ELOF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03639
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.585135
Orbital area, ventrolateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13691
BRD-K78477132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27154
Fetal Heart	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.854656
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.22395
PAX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.162
GTEX-NPJ8-1926-SM-3MJGB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884657
Autoimmune disease of musculoskeletal system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.634
Plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PPP2R2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.267
heart_6b	HPA Tissue Sample Gene Expression Profiles	1.0	1.83537
GSE256181_1_v_0_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
nucleus of the inferior collicular brachium, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33586
TCF3	ENCODE Transcription Factor Targets	1.0	null
Perturb_13936_KD_TTC8_SRP345436	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pacemaker cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.483
GTEX-NFK9-0008-SM-4E3JE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.61833
SLC35B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43157
L363	CCLE Cell Line Gene Expression Profiles	1.0	2.06347
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.66977
BRD-K00046588	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10704
TEK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12688
CISH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75015
SNU-423	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863257
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6131-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BTBD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80087
REST_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6977700-aging-12-102667-s004..xlsx-Stage1-The_identified_3126_dysregulated_LmiRM-CTs_in_stage_1_of_MI_1_day_of_MI_using_our_method_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
SUMO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89857
BRD-K67399222	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28065
CRCGN015_HEPG2_48H:M23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14233
anterior pretectal nucleus, ventral core part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1954
NIHOVCAR3	CCLE Cell Line Gene CNV Profiles	1.0	2.36243
CTTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33109
Intercalated nucleus of amygdala	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.914586
ACHN	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.49435
DMBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01275
cephalothin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7453
cell-cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.105262
MGAT4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98388
GPBP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64898
dorsal part of PcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53117
cortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.03744
HBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54714
GTEX-XPVG-1326-SM-4B65P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960211
Universal_Human_Reference	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.89719
Pericardial effusion	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.381
GSE225656_2_v_3_tsc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GATA2_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73899
FKBP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82367
Anterior olfactory nucleus, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17195
MAPK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63748
Perturb_3326_KO_miR23 cluster_SRP092642	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.5351
CYREN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89022
ENO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08569
TFE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68062
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.863835
YD-49-HM53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.38183
CRELD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49323
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	1.0	1.0593
KIF3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80641
Lung adenocarcinoma_LUAD_TCGA-J2-A4AE-01A-21R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K74039237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07533
BRD-K46588240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15375
GTEX-WH7G-0008-SM-4LVNM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.9051
KAT6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.89202
BRD-K43918582	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49745
Folium-tuber vermis (VII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0736
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.39754
Anteroventral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03421
Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YK-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW1783	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58732
GSE92965_0_v_1_klf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LDAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07479
ZNG1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33167
RAMOS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.37839
BRD-K76588894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38856
CB-16-SY72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.227719
BCL11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63618
Declive (VI)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45197
NET1_KD_GDS4196_436_human_AGS - gastric adenocarcinoma cells - (63 shRNA Knock-Down)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
single-organism developmental process	GO Biological Process Annotations 2015	1.0	null
KIAA1958	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10464
BRD-K29083370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25968
GTEX-R55E-0008-SM-48FCG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95944
SkeletalMuscle	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55362
Adductor magnus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.526
COQ5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51814
superficial stratum of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83537
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-68-8251-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K35480932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67466
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40564
TMEM191C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82487
GSE228263_0_v_1_elesclomol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OIZH-0626-SM-3NB1L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0786
GC-04-UF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.430564
CEBPD-23245923-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NAIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3737
ATXN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15631
CTSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03232
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
GTF2F1_02_157	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.28011
SPACA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9
NCIH226	CCLE Cell Line Gene CNV Profiles	-1.0	-1.8
Prostate adenocarcinoma_PRAD_TCGA-M7-A723-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K62597218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17966
GSE200673,GSE200691_1_v_4_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MYOG	ENCODE Transcription Factor Targets	1.0	null
GTEX-TKQ2-1226-SM-4DXSV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838168
single-organism process	GO Biological Process Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-73-7499-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ITM2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11398
intermediate stratum of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39303
TMEM143	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05978
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20756
BRD-K95543908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07309
TIMM8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03
adenyl ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-S341-1826-SM-3K2AB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894949
PU.1-20513432-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC4060771-170289.f1.pdf-393-DMRT2_DMRT2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K02882086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75179
GTEX-QDVN-0326-SM-2I3FS	GTEx Tissue Sample Gene Expression Profiles	1.0	3.29665
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.47984
CRCGN015_HEPG2_48H:G19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0235
Fetallung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.05741
Perturb_16406_KO_Vgll2_DRP005135	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.89554
Urinary system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HIC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13165
GSE149123,GSE149128_3_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Sarcoma_SARC_TCGA-IS-A3K6-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84805
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.839654
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal impulse conducting system conduction	MPO Gene-Phenotype Associations	1.0	null
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.2251
Cardiac muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.983
STAT3	ChEA Transcription Factor Targets	1.0	null
SHSYSY-RA	BioGPS Cell Line Gene Expression Profiles	1.0	1.50013
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.63632
Primary somatosensory area, barrel field, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0239
BRD-K87743988	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.4008
GTEX-XYKS-2226-SM-4E3IU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845488
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4159-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-18-3409-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1239
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.60973
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MMP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17802
RALGPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61236
IKZF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZSCAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21747
BRD-A51381734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00819
GSE148066,GSE157787_0_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZC3H12C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.782
Lateral plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.946
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.17648
r7 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07409
GTEX-X4XX-0011-R3B-SM-46MWK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31651
PcPL part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01059
H3K36me3_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AB-18-YN11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.235097
GTEX-RWSA-0008-SM-47JYX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.01355
A2780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01455
GSE219195_0_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
TIRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72792
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GZ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YL-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH747	CCLE Cell Line Gene CNV Profiles	1.0	1.59393
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863257
MAGED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22136
IGF1_OE_GDS3484_538_human_MCF-7	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-U4B1-0726-SM-4DXUA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.920061
FB-66-UU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.226185
GTEX-OIZH-0326-SM-2HMKC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70366
salivarygland_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.897537
GSE224556,GSE224557_6_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7784
Eye-macrophage	Tabula Sapiens Gene-Cell Associations	1.0	-0.0661869
chr3_119667913_G_A_b38	GTEx eQTL 2025	1.0	1.38616
roof plate of p2 (epithalamic roofplate)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.30974
PMC12486367-Supplementary_Data2.pdf-327-ZNF263_ZNF263	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K67090705	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67892
Autoimmune disease of skin and connective tissue	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.634
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K66453893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26851
GTEX-XV7Q-0926-SM-4BRVQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.891174
cAMP binding	GO Molecular Function Annotations 2025	1.0	null
voltage-gated potassium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.128
LS513	DepMap CRISPR Gene Dependency	1.0	3.08955
primary motor-sensory cortex (samples)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3358
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.943939
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.72079
BRD-K59308946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37049
GSE239844_7_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
USP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23107
C84	DepMap CRISPR Gene Dependency	1.0	5.49822
GTEX-S7PM-0008-SM-3NM9Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.976641
Perturb_14240_KO_Mtor_SRP106468	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.43324
rostral ventrolateral reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.87325
PSN1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.144
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_induced_genes-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
NH6	CCLE Cell Line Gene Expression Profiles	1.0	1.73247
GSE237040_6_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
monensin-3704	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Infralimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32891
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.52416
GTEX-XQ3S-0626-SM-4BOOB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51864
HS611T	CCLE Cell Line Gene Expression Profiles	1.0	1.38821
A4/FUK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.966552
HSPB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53726
BRD-K26459891	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37733
aklomide	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.21604
GTEX-N7MS-0008-SM-4E3JI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48357
GSE103309_2_v_0_ube3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.960656
GSE190316,GSE190324_1_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UJHI-0826-SM-4IHLM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837433
BB-86-BE19_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.296127
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1347
SUM159PT	DepMap CRISPR Gene Dependency	1.0	5.39773
nucleus subcoeruleus, r1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07697
GTEX-XV7Q-0008-SM-4BRWL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4045
Adverse Event Associated With Cardiac Arrhythmia	DisGeNET Gene-Phenotype Associations	1.0	null
NCI-H1993	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HLX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98542
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOT4-1126-SM-4B66E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35127
PKP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49678
diethylstilbestrol_oncorhynchus mykiss_gpl5478_gse8226	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RPMI-8866	GDSC Cell Line Gene Expression Profiles	1.0	1.85336
GTEX-W5WG-2726-SM-4LMIC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917714
NR2F2_01_89	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60185
III	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.941036
BRD-A83387524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82667
SK-N-SH	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.33395
Acute Myeloid Leukemia_LAML_TCGA-AB-2882-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K02133388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.81673
fertilizedegg	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BF-11A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DPRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58998
C4orf48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63872
orbital frontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.84087
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.91173
Autosomal recessive limb-girdle muscular dystrophy type 2X	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.622
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K78088874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85325
PMC10311050-mmc2.pdf-43-PHOX2B_PHOX2B	Rummagene Transcription Factor Associations 2026	1.0	null
BACH1	ChEA Transcription Factor Targets	1.0	null
FCGRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95623
GTEX-XPVG-0008-SM-4GICH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64893
GTEX-XQ8I-0226-SM-4BOPM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28942
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05603
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056238
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5710-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.67286
HC-92-HE59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.265253
Lung squamous cell carcinoma_LUSC_TCGA-90-A4EE-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Warsaw breakage syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.34
EB2	CCLE Cell Line Gene Expression Profiles	1.0	2.20808
GSE165647_2_v_1_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QVJO-0011-R10A-SM-2S1QJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888735
BRD-K24108193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46939
SEC31A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23271
GTEX-XQ3S-0008-SM-4GIDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19227
Lung squamous cell carcinoma_LUSC_TCGA-90-7767-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100354_PCx_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.47453
RAD51D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72183
BRD-K97373334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08887
SLC35F5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29728
MZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.993917
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4974-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40205
FKBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61221
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.46954
superficial stratum of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64022
BRD-K51511759	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33413
Spinal nucleus of the trigeminal, oral part, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14365
KMS-21BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05603
LRIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77619
BRD-K84178323	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44869
SIPA1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74174
GTEX-XMD1-0008-SM-4AT41	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66497
superficial stratum of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25281
KCTD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07083
BRD-K35383890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33148
VD-08-YA83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.233019
BRD-K76543697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01707
FBXO21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62149
PRSS27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07224
GTEX-OIZG-1026-SM-3LK5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888145
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
Medial amygdalar nucleus, posterodorsal part, sublayer a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01727
icSARS CoV_48Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.35753
PMC11839389-PUL2-15-e70058-s003.xlsx-FLF_TBX4_mergeRNAseqChIPseq-symbol_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5170-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FN3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64767
FOXA1-26457646-LHSAR-HUMAN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
EMILIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36449
intestine	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K12107215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57424
GATA3-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
cardiac cell development	GO Biological Process Annotations 2015	1.0	null
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8521
GATA1	ChEA Transcription Factor Targets	1.0	null
EGR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98549
TMEM200C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25824
TSPAN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21391
apigenin-4578	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045209
RPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16936
MANEA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62891
BRD-K11687039	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59793
BRD-K05939258	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12378
DCAF16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84745
GSE175787_4_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XBEW-0008-SM-4AT3Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15119
C11orf68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.943
muscle cell development	GO Biological Process Annotations 2015	1.0	null
PEMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89616
H2AC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18213
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06451
BRD-K44078665	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.137
GSE147056_0_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CENPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07032
BHLHE40_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CNPY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42252
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6524
ABRAXAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12141
MYC_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.90042
BRD-K59000636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00948
CCDC184	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3152
PABPC1L2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88186
Mesothelioma_MESO_TCGA-SC-A6LN-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Small_Intestine-neutrophil	Tabula Sapiens Gene-Cell Associations	1.0	-0.0661869
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17557
Urinary tract	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC5444746-oncotarget-08-30328-s002.xlsx-SI02_Gene_symbols-1912_ChIP-Seq_H3K9me1_2_demethylation_and_ChIP-Seq_AR_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MOAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36919
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_5991_KD_ZNF438_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.6376
PAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1716
small molecule binding	GO Molecular Function Annotations 2015	1.0	null
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.96737
NB1	CCLE Cell Line Gene Expression Profiles	1.0	1.55472
Lung-endothelial cell of artery	Tabula Sapiens Gene-Cell Associations	1.0	-0.065624
hydroxytoluic-acid	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32807
GTEX-XGQ4-1226-SM-4AT67	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899155
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.987667
Lung-cd4-positive, alpha-beta t cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0661869
FB-66-UU47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.222068
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83537
JM1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RNF166	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10858
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
ME-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
smooth muscle	HPA Tissue Gene Expression Profiles	1.0	0.928132
Retinoschisis_Retina_GSE5581	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-0.909431
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.22817
r11 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.447
r7 part of nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18123
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040443
GTEX-PWN1-0626-SM-48TDT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26049
CRCGN015_MCF10A.WT.HP_24H:C14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2767
Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.18849
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.872437
GTEX-OXRN-2426-SM-2I5EQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.871315
MYH9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30811
Autosomal recessive limb-girdle muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.537
PMC4595011-pgen.1005555.s001.xlsx-BPTF_UP-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
M14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.96261
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_Jurkat_LPS_vs_DC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
MINO	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62032
GATA2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TP53-18474530-U2OS-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE149769_1_v_0_nlrp12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TLE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33306
carbohydrate derivative binding	GO Molecular Function Annotations 2015	1.0	null
GC-04-UF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.408577
PMC6928094-395_2019_765_MOESM7_ESM.xls-DEGs_AR7_vs_Pre-patterned-List_of_differentially_expressed_genes_in_AR7_vs_Pre-patterned_cells_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
RNF214	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82647
PMC10679653-mmc4.xlsx-ISL1_KO_Markers_T_L-Unnamed_0_ISL1	Rummagene Transcription Factor Associations 2026	1.0	null
CHRNA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08401
PTF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55654
left ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.364513
Prostate adenocarcinoma_PRAD_TCGA-EJ-7123-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
colon_8a	HPA Tissue Sample Gene Expression Profiles	1.0	1.2344
Retrosplenial area, lateral agranular part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.40456
REST_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE136627_7_v_1_hdac4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WQUQ-1326-SM-3MJFF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26678
Muscle-tendon cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0667499
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
trim28_23493425_cd71pluster119plus_sorted_from_bone_marrow_lof_mouse_gpl6887_gse44063	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.217085
JHH4	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62443
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE232631_0_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NFIC	ENCODE Transcription Factor Targets	1.0	null
HEATR5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19151
NCI-H2172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.972635
OCUG1	DepMap CRISPR Gene Dependency	1.0	2.84811
GATA3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEIS1-26253404-OPTIC-CUPS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-PSDG-0008-SM-48TE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.76244
TEFM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29468
H1_Cell_Line	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.07408
vertebrate muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4758-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical Intraepithelial Neoplasia	DisGeNET Gene-Disease Associations	1.0	null
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065712
KIF20B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52762
GTEX-X4XX-0011-R6B-SM-46MWP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917012
GTEX-X4XX-0011-R4B-SM-46MWL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.893331
TAL1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51H-06A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.1429
CD99	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25459
GTEX-XOT4-0526-SM-4B66O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88934
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.687369
Lung transplant rejection_Trachea_GSE3418	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	0.997403
GSE231648_4_v_5_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RWS6-0008-SM-47JYV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7465
GNA12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70579
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A1A1-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pallidal islands of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05645
hsa-miR-3187-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
PMC12621392-12864_2025_12212_MOESM2_ESM.xlsx-GSF-F_72h_1-Unnamed_0_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of CoPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.20335
Perturb_9796_OE_Foxd1_SRP132362	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GTEX-QDT8-0008-SM-48U2F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.41462
Declive (VI), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30675
GTEX-TKQ2-0008-SM-4DM5L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06969
BFTC909	CCLE Cell Line Gene Expression Profiles	-1.0	-1.75694
ACTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63136
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.7184
PBX3	ENCODE Transcription Factor Targets	1.0	null
mcf7	HPA Cell Line Gene Expression Profiles	-1.0	-2.39936
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.4625
GTEX-XUJ4-2126-SM-4BOOX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07847
m2 part of pararubral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03833
dorsolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.25815
GTEX-PLZ5-0626-SM-2I5F8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80417
SLC38A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31017
Right_Ventricle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.63014
GTEX-OHPL-1626-SM-2HMIR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934716
BRD-K26620362	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7111
CRCGN014_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.1791
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1902
FUT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71531
GTEX-OXRK-0826-SM-2HMK7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36598
LYL1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K36855468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09114
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.2411
NSFL1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00958
Muscle-smooth muscle cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.062246
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.963765
GEMIN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43431
CDR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14686
AARD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65091
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16713
BRD-K33171119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07875
CFAP418	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62099
hymecromone-4623	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-R55C-0008-SM-48FCF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.7002
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_17_KD_HEK293-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.891606
homeostasis/metabolism phenotype	MPO Gene-Phenotype Associations	1.0	null
NCIH1435	CCLE Cell Line Gene CNV Profiles	-1.0	-1.484
GSE100102_4_v_5_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Skeletal system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.329
t60-adrenal_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	8.4802
CRCGN010_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4027
TP53INP2_KO_GSE54917_384_mouse_Quadriceps muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K42061172	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33849
GSE123836_2_v_3_myf6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_11763_KO_Irgm1_ERP020504	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.99681
PBX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30541
medial tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20649
GSE146074_9_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ABCC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74625
GSE144796_3_v_0_linagliptin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8020666-pnas.2015855118.sd05.xlsx-LPS_24_AAM-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
RARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41922
ECHDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1269
Urogenital Abnormalities	CTD Gene-Disease Associations	1.0	1.20784
BRD-K31778735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32551
GF1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hippocampus (hippocampal formation)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.985137
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08602
PMC11258892-NIHMS2003533-supplement-MMC6.pdf-48-ZNF229_ZNF229	Rummagene Transcription Factor Associations 2026	1.0	null
TBC1D3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43436
posteromedial visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12305
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986235
GTEX-PVOW-0011-R1A-SM-32PL6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39365
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1662
GTEX-WFON-1326-SM-4LVMN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967482
SQ1	CCLE Cell Line Gene CNV Profiles	1.0	1.76836
primary motor cortex (area M1, area 4)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03118
PCM6	CCLE Cell Line Gene Expression Profiles	1.0	1.67972
dorsolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.988826
ADCY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81167
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
rectum_8b	HPA Tissue Sample Gene Expression Profiles	1.0	0.916254
Ventricular septal defect	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.281
GSE205070_1_v_4_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PIK3R4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99065
GSE255432_7_v_3_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CAMSAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07204
layer II of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.86792
VIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.911878
cerebellar cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.24641
GTEX-Q2AH-0008-SM-48U2J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.88993
BRD-K95839423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29355
Brain - Hypothalamus	GTEx Tissue Gene Expression Profiles 2023	1.0	1.74642
Crus I, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01809
ALVA31	BioGPS Cell Line Gene Expression Profiles	1.0	0.968187
Perturb_6589_KO_Zfp708_SRP186171	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.52577
CAKI-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863257
ZNF146	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23078
CEBPD	ChEA Transcription Factor Targets	1.0	null
GTEX-TSE9-0008-SM-4DXT8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.913007
GTEX-PLZ4-0926-SM-2S1OI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874997
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055108
GTEX-WFG8-0726-SM-3GILP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31798
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.53337
A172	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.12563
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.2915
TRIM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45218
Kidney Chromophobe_KICH_TCGA-KN-8423-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K10385824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09529
Declive (VI), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56245
BRD-K93335719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11214
Kidney renal papillary cell carcinoma_KIRP_TCGA-4A-A93Y-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.35155
GSE190316,GSE190324_10_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5EA-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4355-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.894966
mantle zone of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06167
GTEX-WWYW-0011-R6A-SM-3NB3G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46591
Lung adenocarcinoma_LUAD_TCGA-38-4627-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74356
GTEX-X4EO-2726-SM-4E3HS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1317
Muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.014
JJ012	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.34321
CRCGN009_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.57895
21205295-TableS1	GeneSigDB Published Gene Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A6-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD164L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04168
SNUC1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.73752
GSE119498_6_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93944
CPEB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67631
DLG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71069
MYL2	MSigDB Cancer Gene Co-expression Modules	1.0	null
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF_D1_vs_D10-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K08527280	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33261
HSPA14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06774
GTEX-PLZ6-0626-SM-3P61B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960151
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045608
pyramidal layer of taenia tecta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63854
UMUC3	CCLE Cell Line Gene Expression Profiles	-1.0	-1.53201
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GA10	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53505
Salivary_Gland-myoepithelial cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0661869
IRF2BPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09493
SAFB2_02_150	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.22882
GSE129648,GSE129650_2_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RAJI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.57648
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058834
KIF5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.046
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.41453
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.805694
CARD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75335
USP21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30845
GTEX-TMMY-1126-SM-4DXSX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.948214
PBX-27287812-CHIP-SEQ-EMBYONIC-LIMB-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
CRCGN014_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.95623
ATP6V1E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07875
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.94689
ZNF586	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29714
BRD-K98704738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.13462
anterior amygdaloid area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.46667
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.68185
GTEX-XBEW-1526-SM-4AT4K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849644
GTEX-NPJ8-0426-SM-2HMK6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73668
Postsubiculum, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05288
GTEX-T5JC-0011-R5A-SM-32PLK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.94575
Brain Lower Grade Glioma_LGG_TCGA-DH-A7UR-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-5870-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C15orf62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66801
H3K36me3_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Bladder	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TRIM61	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52862
496100657_FWM_probable Alzheimer's disease_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.08425
MYOD1_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MFSD14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1538
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7738-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Connexin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.806
SKNSH	CCLE Cell Line Gene Expression Profiles	1.0	1.47442
MEL270	DepMap CRISPR Gene Dependency	1.0	12.3467
Urinary Bladder Neoplasms	CTD Gene-Disease Associations	1.0	1.32935
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0467
JIYOYE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.71623
RDES	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47449
GTEX-WK11-0626-SM-3NMAV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17652
CCDC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37958
KDM4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10367
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.75509
BRD-K23481525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23065
STAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29079
GTEX-OIZI-0008-SM-2XCFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08962
KIAA1191	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27531
CKM complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.79
intermediate stratum of JcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43008
GSE216273,GSE216292_14_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary auditory cortex (core)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.895521
BRD-K10058823	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64505
GB-46-CK08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.602729
TMUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03904
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.55171
AMOTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38377
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07296
Atrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.139
HEY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.997867
PMC10510228-13287_2023_3481_MOESM7_ESM.xlsx-DEGs-Differentially_expressed_genes_DEGs_in_bone_marrow-derived_MSCs_from_six_human_donors_cultured_at_high_confluency_MSC-HC_versus_low_confluency_MSC-LC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WHSE-0011-R7A-SM-3P5YZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903001
BRD-K19040732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27254
BRD-K00057967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13573
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.815
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_R_species_not_found_in_common_genes_of_LF_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
Musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.634
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.107
Perturb_3030_KO_Acta2_SRP353808	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	13.792
GTEX-WCDI-0008-SM-47JYE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54523
TNFRSF11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87197
SGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32608
cell-cell contact zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.268237
GSE60367_2_v_1_cxcr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Frontal pole, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52534
BACH1-22875853-HELA-AND-SCP4-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ISL1-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50549
r11 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44741
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Retrosplenial area, lateral agranular part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7913
GTEX-XUYS-0008-SM-47JYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51857
GSE196699_7_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE205316,GSE205317_0_v_1_nrip1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SCH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AM-38	GDSC Cell Line Gene Expression Profiles	1.0	1.44921
GTEX-WHSE-0926-SM-3NMBS	GTEx Tissue Sample Gene Expression Profiles	1.0	2.15811
496100358_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.62332
PMC10769395-media-2.xlsx-S2D_EF_Repressed_genes-Ebegboni_et_al_Supplemental_Table_S2D_Increased_expression_following_depletion_of_EWSR1_FLI1_TC-32_TC-71_and_A673_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.82867
COPS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18368
LYL1	ChEA Transcription Factor Targets	1.0	null
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.8185
S1PR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35939
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.885643
oocyte	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
BRD-K33204113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31449
Acute Myeloid Leukemia_LAML_TCGA-AB-2822-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8C_Het1A-HNF4A_2d_5x_closed-Gene_Name_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7061-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7422
DCLRE1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80273
CDK11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72158
CDT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63929
ABC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XPVG-1426-SM-4B668	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970322
GTEX-XQ8I-2326-SM-4BOQC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11301
dorsolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.853486
Pelvic Organ Prolapse	DisGeNET Gene-Disease Associations	1.0	null
substantia innominata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.892521
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
HES7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51707
CLCN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20837
HLA-E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50257
FDX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28552
YY1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00725
abnormal total tissue mass	MPO Gene-Phenotype Associations	1.0	null
PMC5770158-elife-31706-supp3.xls-ISL1_target_regions-Nearest_gene_1_ISL1	Rummagene Transcription Factor Associations 2026	1.0	null
Dystroglycan complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.248
GSE166004_5_v_4_pld1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-ensembl_AR	Rummagene Transcription Factor Associations 2026	1.0	null
EB2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:F14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24445
hippocampus (hippocampal formation)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.917158
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XPVG-1526-SM-4B66C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904711
HE-80-BQ08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.330095
Dystrobrevin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.114
GTEX-RU72-0008-SM-46MV8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30653
PDPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70734
IM-9	GDSC Cell Line Gene Expression Profiles	1.0	1.49018
striated muscle tissue development	GO Biological Process Annotations 2025	1.0	null
pirinixic acid-368	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
anion binding	GO Molecular Function Annotations 2015	1.0	null
C1orf174	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61915
PITPNM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03922
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.9537
FADS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17728
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28726
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACBD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78442
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17256
GTEX-QDT8-0526-SM-3NMD8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925829
H3K36me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PIK3C2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81232
IBA57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38436
lateral part of PcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11579
SUCLA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02603
C17orf97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33212
GSE205316,GSE205317_0_v_3_nrip1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12621392-12864_2025_12212_MOESM2_ESM.xlsx-GSF-S_48h_2-up-regulated_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
RND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41517
GTEX-S4P3-1626-SM-3K2AZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882948
layer III of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.51649
GTEX-WYJK-1026-SM-3NM8W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57779
BRD-K17258761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50816
GSE192663_1_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ESS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
15220918-TableS1a	GeneSigDB Published Gene Signatures	1.0	null
GTEX-RU1J-0526-SM-46MUT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02225
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.92764
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
PCNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34011
NSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82029
GTEX-WZTO-0011-R1B-SM-3NMAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.927057
PA-TU-8902	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.34321
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4813-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.65566
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.835156
GTEX-T6MN-2626-SM-32PMQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.959009
MFE280	CCLE Cell Line Gene CNV Profiles	-1.0	-2.13011
intercalated disc	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.640145
BRD-K27600134	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51823
GSE154081_3_v_0_sildenafil_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HGC27	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35681
PANC-03-27	GDSC Cell Line Gene Expression Profiles	-1.0	-1.85518
GTEX-QEG4-0426-SM-33HC3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49022
DHRS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5505
hsa-miR-3909	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
KCTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0813
mantle zone of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77452
H3K36me3_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0011-R5A-SM-3P5ZO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.98091
CRCGN016_MCF10A.WT.HP_24H:A11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.15467
regulation of heart rate	GO Biological Process Annotations 2015	1.0	null
plumule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071473
BRD-K35726223	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20313
binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K07624584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45313
GTEX-Q2AH-0526-SM-2I3ED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49677
GARRE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81802
JHH-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-3183	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GATA3_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
developmental process	GO Biological Process Annotations 2015	1.0	null
GTEX-O5YW-0326-SM-2I5EI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62064
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19052
GTEX-WQUQ-1426-SM-3MJFD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58123
SF268	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.96261
TRAPPC6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37116
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
SIRT4_KO_GDS4823_30_mouse_hepatocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.88682
SSR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99906
MED26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.589
JVE015	DepMap CRISPR Gene Dependency	1.0	2.93258
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02006
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5VV-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A61C-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA2	ENCODE Transcription Factor Targets	1.0	null
large intestine	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2641
CRCGN016_MCF10A.TP53.M_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.14186
PMC9437808-mmc3.xlsx-IPA_Upstream_regulators-IPA_Upstream_regulator_analysis_Up_regulated_genes_following_LPS_treatment_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Sarcoma_SARC_TCGA-DX-A6BB-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99433
BRD-A17635048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07005
BRD-K61943321	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21676
MCAS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
ELF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9811
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.08631
NR1H2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49554
GATA3	ENCODE Transcription Factor Targets	1.0	null
AKT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73399
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.6012
heterocyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K36908385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13411
HSFY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17109
GTEX-WY7C-0526-SM-3NB3D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93965
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058832
Superior vena cava	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.839
CDKN1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76932
membrane part	GO Cellular Component Annotations 2015	1.0	null
ventrolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.959553
intrinsic component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.124784
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BRD-K88542817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15151
JAR	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-X4XX-0008-SM-46MVK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17912
GTEX-RVPU-0011-R7A-SM-2XCAB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.979663
BRD-K72721410	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93238
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955452
GSE205070_1_v_5_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CHP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42719
BRD-K79946769	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75318
H3K9ac_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HNRNPM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44762
hydroxyprogesterone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2393
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00556
pineal_night	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.07013
PPP2R5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32861
GSE152055_2_v_3_mpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE173810_0_v_1_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ATF6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15416
EEF2K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54366
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0046
SARM_KO_GDS4842_411_mouse_brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
viscus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HDLM2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7658
BRD-K84636055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68061
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.406315
GSE136627_3_v_1_hdac4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.914609
GTEX-XMD1-0011-R10A-SM-4AT4A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.976757
TCF12	ENCODE Transcription Factor Targets	1.0	null
POFUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62525
SAP18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45285
GTEX-U4B1-1226-SM-4DXT7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831043
SNU-16 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.466
DMRT1-23473982-TESTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52939
SPATA2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22665
GTEX-V955-0726-SM-3GAFG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3574
GSE225218_8_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
heart_5b	HPA Tissue Sample Gene Expression Profiles	1.0	2.06551
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.632335
hsa-miR-2467-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GTEX-P78B-1326-SM-3P611	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852685
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.38101
GSE153907,GSE153908_0_v_1_azathioprine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WHPG-1026-SM-3NMBA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09535
GTEX-WEY5-1526-SM-4LMJF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903841
Trachea-mast cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0661869
GSE137325_2_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
dystrophin-associated glycoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.346
GSE135030_11_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4908-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-POYW-0526-SM-2XCEY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939234
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828223
CRCGN015_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.35325
inferolateral temporal cortex (area TEv, area 20)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03352
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.960518
GSE85565_1_v_0_tcf21_human	RummaGEO Gene Perturbation Signatures	-1.0	null
heart muscle	HPA Tissue Protein Expression Profiles	1.0	1.36699
GSK3B_knockdown_208_GDS4305	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.25894
A-431	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39233
MYOG_myocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MORF4L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82037
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
NPPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30604
abnormal sinoatrial node morphology	MPO Gene-Phenotype Associations	1.0	null
striated muscle cell differentiation	GO Biological Process Annotations 2025	1.0	null
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.69998
SHROOM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14531
RHOA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14024
GSE255432_4_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.8469
A-Netherlands-602-2009(H1N1)_7Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.74152
striated muscle cell development	GO Biological Process Annotations 2015	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1Z4-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149075_6_v_4_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FV-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XXEK-0326-SM-4BRVV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.851045
Field CA3, stratum oriens	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35684
GTEX-R45C-0008-SM-48FF2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904646
ALG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15988
G142	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.930833
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05222
intermediate part of r8B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06214
HCC1395	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50282
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16438
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1IB-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K23327891	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.40486
decreased heart rate	MPO Gene-Phenotype Associations	1.0	null
abnormal heart atrium morphology	MPO Gene-Phenotype Associations	1.0	null
BOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84631
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56476
BRD-A03898562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02747
MAPK13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60384
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.88682
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.94791
POTEI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90059
BRD-K37866276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.27042
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
myotome	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.831547
CASC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92679
DE-98-FC24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.249123
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18446
abnormal cardiovascular system physiology	MPO Gene-Phenotype Associations	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2999-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TACC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29384
NDUFAF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2447
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00259
BRD-K04786080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72775
SIRT4_KO_GDS4823_505_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6222-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Micronuclei, Chromosome-Defective	CTD Gene-Disease Associations	1.0	1.08231
BRD-K17343593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32252
LY-294002-5937	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MATN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7002
NPW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55504
PBX3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GINM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.453
Lateral visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24621
MAZ	ENCODE Transcription Factor Targets	1.0	null
STOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60371
dorsolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01136
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	1.0	0.958024
GSE193999,GSE194000_4_v_0_atf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
METTL27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07377
Cardiomyopathy_Myocardial tissue_GSE1869	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.89296
BRD-K14070721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0334
PPARGC1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66659
circulatory system development	GO Biological Process Annotations 2023	1.0	null
PMC10679653-mmc2.xlsx-ISL1_KO_Markers_L-Unnamed_0_ISL1	Rummagene Transcription Factor Associations 2026	1.0	null
CLK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01237
HUG1N	CCLE Cell Line Gene CNV Profiles	1.0	2.00914
BRD-K53717076	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64442
ARHGAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79696
Severe acute respiratory syndrome (SARS)_Peripheral blood mononuclear cell_GSE1739	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.83573
GTEX-X4XX-3026-SM-3NMB2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.930906
GTEX-XV7Q-2226-SM-4BRVY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11451
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4905-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K79517375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78903
VAMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07787
GTEX-WZTO-0011-R10B-SM-4E3KB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.859184
levomepromazine-3701	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K67042874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03299
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.436336
BRD-K73357010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.38585
NB10	GDSC Cell Line Gene Expression Profiles	1.0	2.05704
RTL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20041
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.843833
abnormal response of heart to induced stress	MGI Mouse Phenotype Associations 2023	1.0	null
CRCGN015_MCF10A.TP53.M_24H:F22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6889
PODXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22438
PATZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60777
RAD21	ENCODE Transcription Factor Targets	1.0	null
RD-90-OY66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.49792
GM97	BioGPS Cell Line Gene Expression Profiles	1.0	1.51136
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
Skin disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.634
KCTD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50772
EWSR1_KD_GDS4962_469_human_Ewing sarcoma and prostate cancer	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
r6 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.26907
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28178
LYL1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
KRAS.PROSTATE_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
SARM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.88645
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5027
upper (rostral) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01009
heart muscle	HPA Tissue Gene Expression Profiles	1.0	2.20893
QSOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34031
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12696
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1133
SLC10A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42918
PNPLA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41914
dorsal spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.91062
GTEX-OHPM-0726-SM-3LK7A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04346
BRD-K60861976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.83329
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07172
CELF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85325
SG in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.933312
r7 part of the basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.04492
NCI-H460	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.963765
NAP1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04074
superficial stratum of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16931
Lung-pulmonary ionocyte	Tabula Sapiens Gene-Cell Associations	1.0	-0.0667499
King Denborough syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.652
WM-266-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.82844
JHOS-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE231648_1_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XXEK-1126-SM-4BRUX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48785
MAGEH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96672
CSRNP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34949
TMEM147	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32698
BRD-A07944983	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03362
GTEX-P4PQ-0326-SM-2HMJ8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2596
hippocampus (hippocampal formation)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18163
ICMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12997
r8 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33098
TCF3/E2A-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MC1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13001
GSE216538_1_v_6_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
mantle zone of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11579
BRD-K81510336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44629
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.243
layer 1 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25148
NCIH747	CCLE Cell Line Gene Expression Profiles	-1.0	-2.60973
MYC_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
coelom	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.485935
heart	GTEx Tissue Gene Expression Profiles	1.0	2.15655
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.931986
INSIG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95879
GTEX-RUSQ-0526-SM-2TF72	GTEx Tissue Sample Gene Expression Profiles	1.0	2.57086
regulation of membrane potential	GO Biological Process Annotations 2015	1.0	null
WDR37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96508
WSUDLCL2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.99294
ITGA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7327
PMC10969083__F4	PFOCR Pathway Figure Associations 2024	1.0	null
ASH2L-23239880-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CHD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12452
integral component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.159074
Popeye protein	InterPro Predicted Protein Domain Annotations	1.0	null
REL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5882
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.95471
BRD-K64424704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61841
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
GSE173405_3_v_0_dmba_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
claustrum, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.95972
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE195559_2_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A69E-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE226114,GSE226116_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A5RA-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K61168922	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56905
Long QT syndrome 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.17
BGN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82234
KYSE-510	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.871694
NCIH1734	CCLE Cell Line Gene CNV Profiles	-1.0	-2.34475
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
anterior pretectal nucleus, ventral superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36521
adenyl nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-XPVG-0826-SM-4B654	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3259
superficial stratum of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56971
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.960656
16715129-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
Acute Periodontitis	DisGeNET Gene-Disease Associations	1.0	null
SPI1-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
STARD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59099
888	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.33088
C17orf49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23116
POLR2A	ENCODE Transcription Factor Targets	1.0	null
lateral habenular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.98925
TMEM88B_KD_GPL10558_471_human_cardiovascular progenitors cells differentiated from hES cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.30456
Liver Diseases	CTD Gene-Disease Associations	1.0	1.27533
muscle cell differentiation	GO Biological Process Annotations 2025	1.0	null
anterodorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.917379
GSE151494_8_v_3_nrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NPRL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3863
MYOG_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K53241408	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53881
GTEX-WH7G-0326-SM-3NMBH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35978
PFKFB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62546
GTEX-PX3G-0326-SM-2I3EO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26681
CRCGN015_MCF10A_48H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.16936
CRCGN016_MCF10A.WT.HP_24H:N01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00507
BFTC-909	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intermediate stratum of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61796
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7084
hsa-miR-1183	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GSE185944_0_v_3_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.30222
GTEX-S32W-0926-SM-4AD5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86182
liver	GTEx Tissue Gene Expression Profiles	-1.0	-1.0378
BRD-K94409042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24664
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1863
stomach_3b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.11324
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context3-Gene_Name_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34809
gastric cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.405555
abnormal heart rate	MPO Gene-Phenotype Associations	1.0	null
ILF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21798
ELN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24352
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.13352
CTCF	ENCODE Transcription Factor Targets	1.0	null
NB69	GDSC Cell Line Gene Expression Profiles	1.0	2.68592
MEAK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48085
BRD-K86838462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.13136
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.3598
CCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09899
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.86799
mantle zone of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50072
GTEX-P4QR-0008-SM-48TE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46878
Lung squamous cell carcinoma_LUSC_TCGA-96-A4JL-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE225656_2_v_1_tsc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K87472370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48456
Sarcoplasmic reticulum membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.193
GRIN3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8276
PMC2263127-pone.0001816.s001.xls-E2F3_up_Bild-Symbol_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.894809
plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.133712
Perturb_11860_KO_lincFoxf1a_SRP028547	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.53529
RIMS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36719
GTEX-X261-0326-SM-3NMD4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924242
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.921506
shoot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063493
intermediate stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07409
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5168-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FBXO41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06516
NRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89922
Primary somatosensory area, unassigned, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06647
BRD-K88323568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00734
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8207
regulation of system process	GO Biological Process Annotations 2015	1.0	null
midbrain raphe nuclei	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22264
ZBTB8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61313
ELMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51616
BRD-K31503053	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55031
GSE60217_1_v_0_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31612
dorsomedial hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14727
MYOD1_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K11631946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0696
CRAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23729
X, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.93671
BRD-K32582260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.4399
PTP4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52834
GTEX-U8XE-2526-SM-4E3IT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848292
GSE149264,GSE149267_4_v_3_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dexamethasone_homo sapiens_gpl6480_gds3946	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.32121
ML1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36907
GTEX-WFJO-0826-SM-4LVM5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.911894
CER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04528
TADA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62094
METTL14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84721
Perturb_4707_KD_Dnmt3a_SRP069225	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.9684
Adrenocortical carcinoma_ACC_TCGA-OR-A5J1-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LMO2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SUM149PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.987685
BRD-K41202439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05765
PRM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55882
IFI27L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66761
GTEX-V1D1-1026-SM-4JBHE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16855
Cardiac Arrhythmia	DisGeNET Gene-Phenotype Associations	1.0	null
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18446
LRRC20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09783
GSE127790_4_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SPI1-22790984-ERYTHROLEUKEMIA-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
urinary system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
superficial stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34985
EXOSC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90188
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-H9-A6BX-01A-31R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r1 part of the 'mesencephalic' trigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2275
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U8-11A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6017-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.96261
YRDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33436
BRD-K28414977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.50649
bladder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.959223
BRD-K67007076	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16201
Perturb_7107_OE_Mir378A_SRP047487	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-15.1039
DCPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64007
GTEX-SNOS-0008-SM-4DM6I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36794
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840115
BRD-K11477112	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1541
LLPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64776
DHX35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67497
CB-44-FA25_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.248024
SKNBE2	CCLE Cell Line Gene Expression Profiles	1.0	3.408
GSE107956,GSE107957_0_v_1_ythdf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
VZ in postamygdaloid region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.914169
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Nearest_Ensembl_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE213632_4_v_5_acod1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6939-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HC-74-HM63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.31945
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.83884
MYCN-28898695-NB1643-HUMAN-NERVE-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K86998514	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12989
Lung Neoplasms	CTD Gene-Disease Associations	1.0	1.4294
sinus node	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.22648
heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.205254
BRD-K27911943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7781
DC-93-NP78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.11203
posteroventral (inferior) parietal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26976
IMPA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17728
Sarcoma_SARC_TCGA-KD-A5QU-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.593115
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LX-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lycorine-3891	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-O5YT-1026-SM-3MJGF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03235
EOMES_OE_GDS5077_65_human_RUES2	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
Tongue-endothelial cell of artery	Tabula Sapiens Gene-Cell Associations	1.0	-0.0667499
GSE226439,GSE226441_6_v_2_hnf4g_human	RummaGEO Gene Perturbation Signatures	-1.0	null
IKZF1	ENCODE Transcription Factor Targets	1.0	null
purine nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
bed nucleus of stria terminalis, lateral amygdaloid division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.88575
PMC12660214-Supplementaryfile1.xlsx-Genes_Human_with_ATF3-binding-regulation_of_membrane_potential_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
EKLF-21900194-ERYTHROCYTE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01265
GSE190316,GSE190324_6_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
seed	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06621
Slow muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.043
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00212
TRIM45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33965
Perturb_6011_KD_ERH_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.83821
STAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67922
ranolazine_mus musculus_gpl1261_gse25767	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-T8EM-0526-SM-4DM64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36874
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041307
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.42224
GLS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15585
GSE111035,GSE111040_8_v_9_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE140965_1_v_4_mybpc3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-NL3G-0008-SM-4E3JX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.14062
ZNF695	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67286
Perturb_17661_KO_Lrig2_ERP104806	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.31089
cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.091712
HC-74-HM63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.215408
PDXP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2125
striatum_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.17535
GTEX-PVOW-0011-R5A-SM-32PL7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17592
HPAFII	CCLE Cell Line Gene CNV Profiles	-1.0	-2.50972
MLXIPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67621
hsa-miR-184	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
BRD-K84478344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16298
MLLT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68751
MDAMB435S	CCLE Cell Line Gene CNV Profiles	1.0	1.43117
496100403_TCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.14791
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20N-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal response to injury	MPO Gene-Phenotype Associations	1.0	null
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12568
NAP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37781
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.914907
CRCGN016_MCF10A.WT.HP_24H:F12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1816
GTEX-QLQW-0326-SM-447A8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.834638
ANKRD61	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09969
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.41192
PDRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92321
ion binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-WHSE-0011-R2A-SM-3P5ZL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.868094
BRD-K73795883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37919
PMC9859043-elife-78421-supp9.xlsx-LHX8_P-Gene_symbol_LHX8	Rummagene Transcription Factor Associations 2026	1.0	null
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.99837
MAPK14_knockout_13_GDS2693	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.34535
striated muscle cell differentiation	GO Biological Process Annotations 2023	1.0	null
Gastric adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.75
NID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80597
TRAPPC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43829
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8C_Het1A-HNF4A_2d_5x_closed-Nearest_Ensembl_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
Liver Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.24874
amygdalohippocampal transition zone, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.943173
SG231	DepMap CRISPR Gene Dependency	1.0	3.86861
submedius thalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.089
BRD-K21662756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33725
LRR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2517
vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.665182
SHISA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19031
CA4 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.879874
EP300	ENCODE Transcription Factor Targets	1.0	null
BRD-K16689648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53323
BRD-K61247793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46535
FAM234A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8363
abnormal sinoatrial node morphology	MGI Mouse Phenotype Associations 2023	1.0	null
GSE133070_3_v_1_prss1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.335438
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.954225
BRD-K74948793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62351
inner CP in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.881408
EHEB	CCLE Cell Line Gene Expression Profiles	1.0	1.59393
BRD-K23467057	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33036
rostral division of VL	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29986
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.15909
Lung adenocarcinoma_LUAD_TCGA-44-2657-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney-cd4-positive helper t cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0667499
NDUFS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2323
Brain Lower Grade Glioma_LGG_TCGA-WY-A85D-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OOBJ-0008-SM-3NB26	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04274
GTEX-OXRO-1726-SM-3LK6C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873578
SIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56181
MEX3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74251
HC-74-HM63_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.239856
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69072
GTEX-WHPG-0826-SM-3NMBF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3906
CAPAN1	DepMap CRISPR Gene Dependency	1.0	2.60555
Perturb_5678_KO_Pgr_ERP140354	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
PBDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7422
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GR-06A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.119
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.880737
BRD-K53931904	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16202
Anterior olfactory nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04231
GTEX-PX3G-0008-SM-48U2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.23573
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20Q-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TE6	CCLE Cell Line Gene CNV Profiles	1.0	1.5651
Atrophy	CTD Gene-Disease Associations	1.0	1.06297
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6744
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.64266
BRD-K30962012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04755
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.04607
Right atrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.256
PMC3889689-elife01439s001.xls-RFX2_rnaseq_chip_DirectDE_final-ENSG_ID_RFX2	Rummagene Transcription Factor Associations 2026	1.0	null
Osteopoikilosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.193
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042562
limb-girdle muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.401
Lung squamous cell carcinoma_LUSC_TCGA-18-3410-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-6842-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYO1E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76691
abnormal impulse conducting system morphology	MPO Gene-Phenotype Associations	1.0	null
COLO680N	CCLE Cell Line Gene Expression Profiles	-1.0	-1.77157
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.83776
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05157
NCI-H82	GDSC Cell Line Gene Expression Profiles	-1.0	-2.03549
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060216
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vascular tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.134235
GTEX-UJHI-0008-SM-4IHL1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17343
GRHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5799
BRD-K54622858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70433
496100420_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.95788
TMEM205	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98597
RPS21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55447
BRD-K37680172	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90081
BRD-K63853589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39447
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2412
WBP1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80491
fisetin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18771
FOXP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0977
estradiol_mus musculus_gpl4134_gse23241	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.946322
IER5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0834
Brain Lower Grade Glioma_LGG_TCGA-RY-A83Z-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Branchial arch	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.166
GSE201361_0_v_1_mpst_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LHX1_KO_GDS2748_298_mouse_embryonic renal vesicles	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GPATCH2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13847
TYSND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63663
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.946524
LRP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55914
posteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62999
chrysin-3106	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CACNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86941
SMARCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88841
BRD-K74701308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28884
bladder	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.6661
NAA16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.73448
BRD-K88128293	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20699
TRAK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05318
BRD-K50474387	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.63728
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
ATF3_02_180	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.52356
GTEX-VUSH-0008-SM-47JWK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28518
GTEX-NPJ8-1826-SM-2YUNC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26413
DE-73-EF24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.324091
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2083
GTEX-WYJK-1126-SM-3NM9Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24131
karpas707	HPA Cell Line Gene Expression Profiles	1.0	1.22714
SRSF4_02_12	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.04836
RPUSD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13238
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.634
BRD-K29086754	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38791
GTEX-WYBS-1226-SM-3NM9N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08015
BRD-K29636267	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27268
Lung adenocarcinoma_LUAD_TCGA-38-A44F-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE166536_1_v_2_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Field CA1, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08363
GTEX-QEL4-0008-SM-447AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66978
Lung squamous cell carcinoma_LUSC_TCGA-85-A4PA-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5487
19658189-TableS3	GeneSigDB Published Gene Signatures	1.0	null
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
dorsolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.913235
spanning component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.200328
CPTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60589
CLDND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9804
MTRF1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47325
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PMC11111877-41598_2024_62256_MOESM7_ESM.xlsx-Table_S1-Supplementary_Table_S1_The_intersect_genes_of_AR_and_RNA_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GA-88-CF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.233798
Anterior cingulate area, dorsal part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51072
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.849019
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.838448
BRD-K61022988	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06225
FOXD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30033
GTEX-UTHO-0008-SM-4JBID	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54413
GTEX-RM2N-0008-SM-48FF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43892
GTEX-S341-1226-SM-4AD5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.992483
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.1734
Dorsal peduncular area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.97298
GTEX-T2IS-0008-SM-4DM75	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84707
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-Fay_Thermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K36me3_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE58724_1_v_4_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
AC-49-NG46_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.318342
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.27321
NSD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65129
PRSS22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97131
GTEX-VJWN-0426-SM-3GIJI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99069
cellular_component	GO Cellular Component Annotations 2015	1.0	null
A-Netherlands-602-2009(H1N1)_24Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.36024
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50411
CCRF-SB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.58729
Prostate adenocarcinoma_PRAD_TCGA-EJ-7783-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUZC-1526-SM-4BRV4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10486
PDLIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14445
HDHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73941
HNF4A-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
HCC70	CCLE Cell Line Gene CNV Profiles	1.0	1.74279
primary motor cortex (area M1, area 4)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19643
GTEX-NL4W-0011-R9a-SM-2I3G1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.946192
ZNF132	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99372
GSE185865_0_v_1_celf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4957230__F4	PFOCR Pathway Figure Associations 2024	1.0	null
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K87995704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0069
BRD-K17176016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30713
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.35589
GTEX-U3ZM-0626-SM-4DXTV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891756
CRCGN017_MCF10A.WT.HP_24H:P18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6013
GTEX-WFG7-0726-SM-3GIKO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.16827
GSE239578_0_v_6_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
G28T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.96564
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WI4N-0626-SM-3TW8Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74625
SPECC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5405
EA-18-FP00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.289047
Mesothelioma_MESO_TCGA-LK-A4NW-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bicellular tight junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.203
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.36
LYRM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94926
GSE181517_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863257
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.77008
Perturb_5670_KO_C2_SRP291131	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.149
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.117
HOXD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05563
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB1-F2del_3Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.32441
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-JUN_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TML8-1826-SM-32QOR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916757
GTEX-TMMY-0008-SM-4DXU3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20547
BRD-K39705203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16585
LHFPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10727
GTEX-REY6-1226-SM-48FDR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.896754
BRD-K15128331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.48233
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.08216
GTEX-OOBK-2025-SM-3LK5S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909282
SIRT4_KO_GDS4823_22_mouse_Liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HCC2185	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.538688
B3GALT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87603
Heart conduction disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.194
GA-88-CF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.455052
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F8-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPI1	ChEA Transcription Factor Targets	1.0	null
REXO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70702
GTEX-S4Z8-1226-SM-4AD6W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989579
ATG16L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4651
GTEX-XMD1-0011-R2B-SM-4AT5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0056
Lyf-1	MotifMap Predicted Transcription Factor Targets	1.0	null
PNRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2445
hippocampus (hippocampal formation)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13052
BRD-K41289356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27375
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.30221
GTEX-R53T-0008-SM-48FEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55941
Anterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03441
intermediate stratum of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81981
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.605306
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.82147
GSE58724_3_v_4_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
LACTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29081
OCIAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42986
AD-16-HL96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.437649
SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.88433
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03967
cyclic-nucleotide phosphodiesterase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.723
ZSCAN20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65085
GSE231745_1_v_0_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
IGBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63573
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.014
OCUM1	DepMap CRISPR Gene Dependency	1.0	2.34582
GTEX-WFG8-0626-SM-3GILJ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.23122
GSE228894_3_v_2_rnmt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
USF1_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5958
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K13309514	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6982
BRD-K27139040	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68802
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.922576
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.960656
IDRA-21	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23849
Subiculum, dorsal part, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.87857
JVM-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE157777_1_v_0_foxa3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10592471-NIHMS1912771-supplement-7.xlsx-D-Enh_vs_AA-all_DE-Aza_atRA_DE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K86903429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17414
GTEX-W5X1-0826-SM-3GILN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51229
Infertility, Male	CTD Gene-Disease Associations	1.0	1.50348
external globus pallidum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11283
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GTEX-T6MN-0011-R1A-SM-32QOY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917961
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R1-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EP300_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MRPL34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22921
mantle zone of JcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25281
C1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1182
abnormal body composition	MPO Gene-Phenotype Associations	1.0	null
GSE231648_4_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsal part of JcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39171
KPNSI9S	CCLE Cell Line Gene Expression Profiles	1.0	1.67159
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ID3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91639
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.41894
lateral subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13636
olfactorybulb	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.05245
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.15166
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_induced_genes-Unnamed_6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21369
GATA3-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_10679_KD|Mut_Cux1|Nras_SRP292900	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.05599
CEP57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12064
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05421
TP53-18474530-U2OS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-RU72-0011-R7A-SM-2TF5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10635
chr3_119656594_G_A_b38	GTEx eQTL 2025	1.0	1.51063
pacemaker cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.16737
BRD-K29661539	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80187
MYL12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17776
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04171
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10071
FOXA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05467
GTEX-RU72-0326-SM-2TF5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73871
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.860787
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6132-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE216538_0_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EP300_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5177-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WEY5-1126-SM-4LMIE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982039
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6090-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS 766T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.16429
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7828-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
urinary bladder	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)HAAvirmut_2day-MOI-10^4_None_GSE37572	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.65883
GSE199255,GSE199356_3_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PPP1R2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.663
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.634
DB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45744
GTEX-UJMC-0526-SM-3GAE3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39129
AB-09-EA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.432385
BCL11B_KO_GSE9330_4_mouse_brain (striatum)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.43455
GTEX-O5YV-0326-SM-2I5H2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.18607
subbrachial nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54034
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHURC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.65349
GTEX-XYKS-0226-SM-4BRW3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36395
BRD-K67090914	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56153
Catecholaminergic polymorphic ventricular tachycardia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.234
GTEX-UJHI-0626-SM-3DB8T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.894131
HOXC12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.43
KCNA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51206
GSE216538_1_v_3_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cerebellar cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.40379
sarcolemma	GO Cellular Component Annotations 2023	1.0	null
RABEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46545
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.97053
EKLF-21900194-ERYTHROCYTE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XAJ8-0726-SM-47JY5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08081
BRD-A89575866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08547
BRD-K31510624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45015
GTEX-S7SF-0926-SM-4AD4M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10561
CRCGN010_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.07145
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23996
GSE103068_5_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PPIH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89792
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.076
HCC1937	CCLE Cell Line Gene CNV Profiles	1.0	2.433
DHDDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83184
BRD-K74506886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69294
DIP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96377
capan2	HPA Cell Line Gene Expression Profiles	-1.0	-0.974373
GSE125025_2_v_3_lyl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EMC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77019
Lung-cd8-positive alpha-beta t cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0667499
GTEX-PWOO-0826-SM-48TCL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30974
AP2M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0248
GSE211286_1_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PVOW-0426-SM-2XCF8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17075
GTEX-UPK5-0326-SM-3GAF3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71137
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.43793
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.68106
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21538
NLGN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1096
Lymph_Node-stromal cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0661869
PBRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62681
PHC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94116
reticular formation of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22429
CL14	CCLE Cell Line Gene Expression Profiles	-1.0	-1.68852
ventral reuniens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42252
NPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51951
GTEX-V1D1-0526-SM-4JBGW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17916
FRMD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37724
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0961
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
GATA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.082
solitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.43038
GTEX-W5X1-0008-SM-4LMKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07588
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04813
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
Perturb_17487_KO_Elavl1_SRP153419	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.0308
Membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
BE-31-XV38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.2734
CA2 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05832
Small_Intestine-goblet cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0661869
GTEX-U3ZN-0008-SM-4DXTL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19922
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.41055
Prostate-nkt cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0667499
SC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.975757
H3K4me1_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
shsy5y	HPA Cell Line Gene Expression Profiles	1.0	2.7193
Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7GZ-11A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WDCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45193
LRFN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.24042
Interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02252
CRCGN015_MCF10A.TP53.M_24H:J07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9948
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.7165
GSE186440,GSE186443_1_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Perturb_16994_KO_Elp3_ERP121703	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.93952
CDK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0333
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A4AW-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sinoatrial node cell development	GO Biological Process Annotations 2015	1.0	null
Perturb_7807_KD_CSTF2_SRP071700	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.95816
GSE183316,GSE183317_1_v_2_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SP in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.841501
HMGB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59602
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039221
NCIH1650	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52843
endocardium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.65056
EP300_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pararubral nucleus, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.1474
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE190681_1_v_0_rtcb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5577301-in-17-237-s001.xls-AR_downregulated_DEGs-Heart_GSE4470_GENE_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NPJ7-0011-R9a-SM-2TC5R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.980929
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.83168
BRD-K36368568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.13351
GSE133213_11_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
skeletal muscle tissue development	GO Biological Process Annotations 2025	1.0	null
GSE157777_2_v_0_foxa3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ATP6V0A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52663
SPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26462
Subiculum, dorsal part, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07567
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02559
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.152
PMC11960529-mmc4.xlsx-Ventricular_ZNF711_KOoverCT-gene_ZNF711	Rummagene Transcription Factor Associations 2026	1.0	null
anterior pretectal nucleus, dorsal core part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61758
decreased body weight	MPO Gene-Phenotype Associations	1.0	null
GTEX-POMQ-0326-SM-2I5FO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28929
GTEX-X4XY-0008-SM-46MVL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.82089
BRD-A78125048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61876
Leiomyoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.818
GTEX-R45C-0926-SM-3GAD4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.372
KYAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96098
Cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.699
Muscle-slow muscle cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.064498
GSE95077_1_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
HS821T	CCLE Cell Line Gene Expression Profiles	1.0	1.43523
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9434
SARS-CoV MA15_Day2-PFU-10^4_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.58109
MYCBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46674
GTEX-XLM4-0008-SM-4AT4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10709
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4988-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DUSP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14805
LAMTOR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04416
PSME2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04333
MFE-280	GDSC Cell Line Gene Expression Profiles	-1.0	-1.49986
STOML1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92138
FOXO1_KD_GDS2720_477_mouse_LSK	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Anterior cingulate area, ventral part, 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16294
GTEX-X3Y1-0226-SM-3P5Z5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32997
Adductor longus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.611
PPP2CB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5025
CRCGN010_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02308
CRCGN015_MCF10A_48H:D24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.33227
GSE231648_0_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZFP92	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3114
BRD-K18178356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00163
tectal gray formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44595
TCF12_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
heart	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BRD-K62547690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36407
posteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27875
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4827
periventricular stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41961
HCCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11647
Pectoral fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.081
hsa-miR-335-5p	MiRTarBase microRNA Targets	1.0	null
AC-84-QG99_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.266948
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.835156
BRD-K64704925	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74861
CCDC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99633
TAL1_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CENPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31403
levallorphan-tartrate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.29814
TMEM35B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86378
hippocampus (hippocampal formation)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.941223
MEOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15308
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20235
hsa-miR-3975	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.80757
KYSE-510	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.88355
external granular (germinal) layer of upper rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16464
hsa-miR-4476	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
CORL51	CCLE Cell Line Gene CNV Profiles	1.0	1.35215
BRD-K23593468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17411
altered response of heart to induced stress	MPO Gene-Phenotype Associations	1.0	null
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.976188
camp binding	GO Molecular Function Annotations 2015	1.0	null
Retrosplenial area, dorsal part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12638
KYSE270	CCLE Cell Line Gene CNV Profiles	1.0	1.75407
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Gene_Name_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
Subiculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10894
ZNF691	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41496
HT-144	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K25710391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33528
CAOV3	CCLE Cell Line Gene CNV Profiles	1.0	1.82653
Subiculum, dorsal part, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.12769
TEX264	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16149
BRD-K37387086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07476
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.69079
BRD-K26376097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0918
VIIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.839461
posteroventral (inferior) parietal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.81515
BRD-K14799424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08056
SHISA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4056
EP300_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K15201964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51377
Perturb_4651_KO_Tip55_SRP134924	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.18315
ACD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7402
GSE235066_4_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Left ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.3
GTEX-R55G-0526-SM-2TC5O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80245
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2412
CRCGN016_MCF10A.TP53.M_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.44389
smoothmuscle_8c	HPA Tissue Sample Gene Expression Profiles	1.0	1.2118
nucleus of the inferior collicular brachium, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.89861
HCC33	CCLE Cell Line Gene Expression Profiles	1.0	1.41058
ARNT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65777
GSN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19873
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00143
GSE215351,GSE215794_4_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	3.16434
NET1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93778
UBA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3408
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38646
abnormal postnatal growth/weight/body size	MPO Gene-Phenotype Associations	1.0	null
H2AC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99894
HIPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56382
Rectum adenocarcinoma_READ_TCGA-AG-3742-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Wolfram syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.061
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4345-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_6968_KD_Dnmt3a_SRP075146	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.5898
BRD-K42797038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20626
PMC9541747-AGE-53-680-s003.xlsx-TableS6-Table_S6_Genes_with_missense_mutations_in_Yaroslavl_cattle_MAF_0_1_and_FST_0_4_in_the_1000_Bull_Genomes_Run_9_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
pallidal amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.83895
GTEX-OHPK-0008-SM-4E3JL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44267
UBB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58903
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.859151
HOXC9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3207
Nucleus of the trapezoid body	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07835
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IMPACT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36034
GTEX-NL3H-0008-SM-4E3HU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.20592
USF2	ENCODE Transcription Factor Targets	1.0	null
postnatal growth retardation	MPO Gene-Phenotype Associations	1.0	null
GSE181517_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17399
Brain Lower Grade Glioma_LGG_TCGA-FG-6692-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lomofungin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27261
FLNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73544
GTEX-TMMY-1526-SM-4DXST	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921451
TAF1	ENCODE Transcription Factor Targets	1.0	null
Anteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33053
BRD-K28108927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08266
GLTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33606
496100489_HIP_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.20401
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5988-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IGR39	DepMap CRISPR Gene Dependency	1.0	5.25881
GTEX-Q2AH-0826-SM-48TZN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07798
hsa-miR-1184	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
BRD-K33064989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33344
GTEX-XQ8I-0126-SM-4BOPL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22039
BRD-K27540772	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51403
r11 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16486
BRD-K30217326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72191
Coronary artery smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.718
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072544
rostral interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23948
GSE191174_0_v_1_ccdc92_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.224
NCI-H1734	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.845776
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.1738
SF539	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.06935
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6648
PMC5444746-oncotarget-08-30328-s002.xlsx-SI01_ChIPSeq_H3K9me_AR-Gene_Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
EPHX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12122
myclobutanil	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01871
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Nearest_Ensembl_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22282
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4968-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Retrosplenial area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10867
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.615
TUG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89323
GSE181966_0_v_3_has2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SUCS-1626-SM-32PLS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89231
HSD11B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2762
layer I of piriform cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00255
Medial pretectal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19587
Prostate adenocarcinoma_PRAD_TCGA-G9-6348-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC15	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37106
GD-66-XE49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.748256
PMC10243915-uxad037_suppl_supplementary_table_s1a.pdf-232-ZNF582_ZNF582	Rummagene Transcription Factor Associations 2026	1.0	null
GNRH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6725
Adams-Oliver syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.211
Primary somatosensory area, barrel field, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01593
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A13J-11A-13R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
ASXL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37188
GTEX-WFON-1526-SM-4LVMP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02008
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18388
GIMEN	DepMap CRISPR Gene Dependency	1.0	4.76313
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.6014
ATG4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28079
Spinal nucleus of the trigeminal, oral part, caudal dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01717
GTEX-U3ZN-1626-SM-4DXTZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.918627
Lung adenocarcinoma_LUAD_TCGA-MP-A4TD-01A-32R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAL1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
mantle zone of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.83329
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055087
abnormal sinoatrial node conduction	MGI Mouse Phenotype Associations 2023	1.0	null
sinus bradycardia	MPO Gene-Phenotype Associations	1.0	null
hsa-miR-4765	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
BRD-K44309337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28435
FN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82375
GSE158458_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ventral part of JcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25236
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.45248
mesoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.36825
BRD-K29328556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2042
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13171
NELFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18391
BRD-K65789952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33834
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.32767
SPEGNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08787
Ebolavirus(EBOV)_1day_PBMCs_17725815_GSE8317	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	0.059114
GTEX-WFON-0926-SM-4LVMK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851309
HAND2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE121824,GSE121826_0_v_2_scaf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WL46-0011-R7A-SM-3LK7X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46695
medial geniculate complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16871
CCAR2_02_146	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.54432
BRD-K93040255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10549
E2F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55058
Kidney-nk cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.065624
Large intestine	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-P4QS-0326-SM-2I3EU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23784
USF2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22899
Weight Loss	CTD Gene-Disease Associations	1.0	1.33612
FOSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.99949
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Greenberg dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.264
BRD-K66299486	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82167
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.96261
CCDC93	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.73338
Lung squamous cell carcinoma_LUSC_TCGA-37-A5EM-01A-21R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BARHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29364
Transmembrane actin-associated (TAN) line	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.708
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.960656
SIRT4_KO_GSE56321_391_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08232
OF-05-CB18_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.734236
PMC12621392-12864_2025_12212_MOESM2_ESM.xlsx-GSF-F_72h_2-up-regulated_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
DF-32-EL16_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.214685
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.963765
BRD-K55508908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48238
GSE216273,GSE216292_0_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mafb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.0481
NEUROD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42524
Tongue-pericyte cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0661869
mantle zone of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.447
GTEX-U8XE-1126-SM-3DB8W	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02136
BRD-K76611906	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08081
Perturb_9498_KO_Lsd1_SRP096254	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.51201
RUNX1	ChEA Transcription Factor Targets	1.0	null
DMRT1	ChEA Transcription Factor Targets	1.0	null
Perturb_4966_KO_Setdb1_SRP226379	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.65087
Brain Lower Grade Glioma_LGG_TCGA-FG-A6J1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27313
GTEX-U8T8-1426-SM-3DB9H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852794
RPS23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15967
MZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.922483
Psoas_Muscle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.0128
Atrial fibrillation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.707
GSE200673,GSE200691_2_v_4_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K92725027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09473
PMC8582123-13073_2021_996_MOESM3_ESM.xlsx-PITX1-HIT_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K16643911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21425
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.46901
Enteric plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.72
KCNH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12246
BHMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27678
H2BC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30955
intermediate part of the arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06781
PMC10709143-41556_2023_1271_MOESM9_ESM.xls-Up_in_PAX7-Target_name_PAX7	Rummagene Transcription Factor Associations 2026	1.0	null
CLMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19887
Hypertrophy	CTD Gene-Disease Associations	1.0	1.39142
RBFOX2_02_139	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.926
cyclic nucleotide binding	GO Molecular Function Annotations 2025	1.0	null
Vitiligo	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.634
HOXC10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6857
basal nucleus of Meynert	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.937679
periaqueductal gray substance, dorsolateral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05096
GTEX-SUCS-0008-SM-4DM53	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.07238
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.858066
CRCGN008_HEPG2_24H:F12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.09855
SKMEL5	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.22985
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31733
DOCK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41912
BRD-K67036882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19008
BRD-K27915221	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16671
Cancer of the testis_Testis_GSE1818	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.64347
Eye-retinal blood vessel endothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.065624
Retrosplenial area, dorsal part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15256
GTEX-P4QS-0008-SM-48TDY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53613
SCAMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27164
SP in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.24993
PCBP2_02_135	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.16993
H3K36me3_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RN64-0008-SM-48FEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46368
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MG-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4341-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77489
PNPLA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01115
Adrenocortical carcinoma_ACC_TCGA-OR-A5K0-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4P3-0426-SM-4AD56	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.992946
PSMA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60098
GSE199204,GSE211619_4_v_6_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
FUS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56861
Alimentary canal	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K15879529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58186
ZKSCAN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2479
umbilicalcord	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07371
GTEX-OXRK-0008-SM-3NB28	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.47307
ATF3-23680149-GBM1-GSC-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
IZUMO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39497
CDIPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68335
NT5DC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87566
Stomach cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.182
S0-EE-Y7IR_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.248726
embryonic stem feeder layer	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.933722
squamous epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.322414
GLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04828
PARK7_KD_GDS3750_2_human_SH-SY5Y	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ANO8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79356
superficial stratum of r5BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74966
KANK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37854
GTEX-RNOR-0008-SM-48FEY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35698
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.93971
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Dilated cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.343
GTEX-X4EP-0326-SM-3P5Z6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46397
GSE147613_1_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF835	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37121
lateral subdivision of BNST	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.927379
GRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87843
NEK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20933
Uterine Cervical Neoplasms	CTD Gene-Disease Associations	1.0	1.35763
magnocellular (medial) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.894619
GTEX-U8XE-0926-SM-3DB8V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23634
BRD-K63757821	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53327
ventrolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.1285
HCC1419	DepMap CRISPR Gene Dependency	1.0	3.01464
GSE60217_1_v_8_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8046-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Eye-limbal stromal cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.065624
BRD-K25387295	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15549
BRD-K32145037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28669
Mesothelioma_MESO_TCGA-LK-A4O6-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SF3B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66844
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.875818
MV-4-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.29846
METTL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18039
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.942209
Super elongation complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.733
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.44803
ADAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69398
MAP1LC3B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98488
intermediate part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77391
GSE122215,GSE122217_0_v_4_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11216188-peerj-12-17616-s013.pdf-68-ZBED2_ZBED2	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.33732
heparin_homo sapiens_gpl570_gse12710	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TSPAN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02196
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34209
CD81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2023
purine ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
GSE195559_6_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GC-04-UF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.312298
GTEX-WEY5-0008-SM-4LMKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.824882
BRD-K62909525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88537
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K21232462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49113
layer 3 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00021
GTEX-OIZH-1526-SM-3NB1J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895313
estradiol_homo sapiens_gpl14550_gse35034	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE168596_1_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.96261
KPNA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34635
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7238-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TMEM88_KD_GSE43805_682_human_hES cells differentiated along the cardiac lineage	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CARNMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70561
GTEX-RVPU-0011-R3A-SM-2XCAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.925155
RXRA	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7245-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null