association dataset threshold value standardized value NAMALWA CCLE Cell Line Gene CNV Profiles 1.0 2.75491 Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lateral habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.08649 central glial substance Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 3.26578 DB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.85579 EW-18 COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.143 CLP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15946 Skin Cutaneous Melanoma_SKCM_TCGA-FR-A726-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BICR16 CCLE Cell Line Gene CNV Profiles -1.0 -1.85743 Intestinal cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.11 reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.42364 Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A820-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDAMB468 CCLE Cell Line Gene CNV Profiles 1.0 1.6379 Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A42Q-01A-11R-A23W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF550 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28461 HGC-27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.832758 RERFGC1B DepMap CRISPR Gene Dependency 1.0 3.41793 PATU8902 CCLE Cell Line Gene CNV Profiles -1.0 -2.00345 G-401 COSMIC Cell Line Gene Mutation Profiles 1.0 null endocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054908 Colorectal Carcinoma DisGeNET Gene-Disease Associations 1.0 null SCML2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61818 NCIH2342 CCLE Cell Line Gene CNV Profiles -1.0 -1.86073 oculomotor nuclear complex, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.870857 RH30 DepMap CRISPR Gene Dependency 1.0 3.12368 DMS-114 COSMIC Cell Line Gene Mutation Profiles 1.0 null KM-12 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22319 urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null lateral group of nuclei, right, dorsal division Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.32286 COV413A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.10689 NCI-H1355 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.984716 Sarcoma_SARC_TCGA-X6-A8C6-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null emboliform nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.30495 PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null AR-20517297-VCAP-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null PL-21 COSMIC Cell Line Gene Mutation Profiles 1.0 null icSARS CoV_54Hour_None_GSE37827 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.5674 Developmental dysplasia of the hip 2 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.847 Uterine Carcinosarcoma_UCS_TCGA-N5-A4RD-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null tamoxifen_homo sapiens_gpl6480_gse12665 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3365-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null testis GeneRIF Biological Term Annotations 1.0 null MCF10DCIS.COM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.37706 nucleus LOCATE Predicted Protein Localization Annotations 1.0 null SSRP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92718 PE01 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.03446 CTCF ENCODE Transcription Factor Targets 1.0 null corpus callosum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.21291 SIHA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15448 POU2F2 JASPAR Predicted Transcription Factor Targets 1.0 null salivary gland GTEx Tissue Gene Expression Profiles -1.0 -1.29873 Gonadal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.406 IGROV1 DepMap CRISPR Gene Dependency 1.0 4.34596 gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053618 CTCF_skin fibroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RBPJ-21746931-IB4-LCL-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41O-01A-12R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ARTN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01491 anterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.826032 lateral orbital gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.848101 endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null JHH6 DepMap CRISPR Gene Dependency 1.0 9.46497 SW1271 CCLE Cell Line Gene CNV Profiles -1.0 -1.38593 A4-FUK COSMIC Cell Line Gene Mutation Profiles 1.0 null Cell type cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.244 PMC9643473-Table1.xls-MAF_0_005-Gene_refGeneWithVer_MAF Rummagene Transcription Factor Associations 2026 1.0 null GTL-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.903939 NONO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79081 Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A4JJ-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NRF1 JASPAR Predicted Transcription Factor Targets 1.0 null KPL-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.39958 layer II of rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.55724 DU-145 COSMIC Cell Line Gene Mutation Profiles 1.0 null bed nucleus of stria terminalis, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.14077 RELA JASPAR Predicted Transcription Factor Targets 1.0 null PC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00766 VMRCLCD CCLE Cell Line Gene CNV Profiles -1.0 -1.40616 lateral hemisphere of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.932114 HUH-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null RSC1A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86179 medial mammillary nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.21064 HELA COSMIC Cell Line Gene Mutation Profiles 1.0 null immunodeficiency-centromeric instability-facial anomalies syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.054 superficial layers of olfactory entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.02554 H3K9me3_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PA-TU-8902 COSMIC Cell Line Gene CNV Profiles -1.0 -2.91612 Lung squamous cell carcinoma_LUSC_TCGA-18-4083-01A-01R-1100-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DBTRG05MG CCLE Cell Line Gene CNV Profiles 1.0 1.42199 Female reproductive organ cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.381 interpositus (intermediate) nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.39453 NCI-H1568 COSMIC Cell Line Gene Mutation Profiles 1.0 null SMRT-27268052-CHIP-SEQ-BCELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null VMRC-LCD Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.40066 E2F1 JASPAR Predicted Transcription Factor Targets 1.0 null MKN28 DepMap CRISPR Gene Dependency 1.0 3.07424 estradiol_homo sapiens_gpl14550_gse35034 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null head of caudate nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.885065 SW684 COSMIC Cell Line Gene Mutation Profiles 1.0 null HCC2885 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.53804 CTCF_lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-CH-5772-01A-11R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RPMI-8866 COSMIC Cell Line Gene Mutation Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M9-01A-23R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-7211-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SK-GT-2 COSMIC Cell Line Gene CNV Profiles -1.0 -2.91612 X, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.41426 dorsal lateral geniculate nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.969283 Breast Carcinoma DisGeNET Gene-Disease Associations 1.0 null paraventricular nuclei, right of thalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.92444 POLR2A ENCODE Transcription Factor Targets 1.0 null COLO 206F Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08302 medial geniculate complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.64298 ventral medial nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.21395 RBPJ-21746931-IB4-LCL-HUMAN ChEA Transcription Factor Targets 2022 1.0 null A704 COSMIC Cell Line Gene Mutation Profiles 1.0 null ventromedial hypothalamic nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.83933 DOV13 COSMIC Cell Line Gene Mutation Profiles 1.0 null male reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.238108 inner CP in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.983144 Thoracic cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.239 Edinger-Westphal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.06417 D-542MG COSMIC Cell Line Gene Mutation Profiles 1.0 null TK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.949986 Lung squamous cell carcinoma_LUSC_TCGA-68-8250-01A-11R-2296-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Carcinoma, Ovarian Epithelial DisGeNET Gene-Disease Associations 1.0 null deep layers of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.31079 cuneus, left, striate Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.963529 EKVX DepMap CRISPR Gene Dependency 1.0 2.00834 outer SZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.09107 SNU-484 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15448 prostate gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null septal nuclei, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.6505 HCC1493 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.40028 PRPF4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29125 PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null TE-15 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCI-H2342 COSMIC Cell Line Gene CNV Profiles -1.0 -2.91612 KNS-62 COSMIC Cell Line Gene Mutation Profiles 1.0 null GA-10 COSMIC Cell Line Gene Mutation Profiles 1.0 null lateral hypothalamic area, mammillary region, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.12119 OCILY19 DepMap CRISPR Gene Dependency 1.0 4.766 inner CP in orbital frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.1229 SKN-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null reproductive GeneRIF Biological Term Annotations 1.0 null spinal (inferior) vestibular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.856133 pyramidal layer of caudal subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.90534 ZR-75-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00534 HEC251 DepMap CRISPR Gene Dependency 1.0 2.56397 Respiratory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.168 indusium griseum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.25923 UCSD-242L Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.869245 BEN COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC3419980-leu201249x2.xls-RUNX1-ETO_siRE_ChIPSeq_peaks_ge-gene_name_RUNX1 Rummagene Transcription Factor Associations 2026 1.0 null ctnnb1_21565795_adrenocortical_adenomas_lof_mouse_gpl570_gds3912 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.04441 paravermis of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.89517 CAL-12T COSMIC Cell Line Gene Mutation Profiles 1.0 null EFM-192A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.903996 H3K9me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null demonstrated GeneRIF Biological Term Annotations 1.0 null epithelium TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null internal male genital organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.285671 Sarcoma_SARC_TCGA-MO-A47R-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A77O-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JHH6 CCLE Cell Line Gene CNV Profiles 1.0 2.71071 Lower respiratory tract disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.154 PRDM14-20953172-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SPI1-20517297-HL60-HUMAN ChEA Transcription Factor Targets 2022 1.0 null inner CP in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.31435 HCC515 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09751 AR-20517297-VCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-LT-A8JT-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null outer CP in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.43171 AR ChEA Transcription Factor Targets 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A9PF-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null prostate gland epithelium TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null SET-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.45919 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-ZJ-A8QR-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TRIM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05181 SN12C COSMIC Cell Line Gene Mutation Profiles 1.0 null COLO 205 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.974818 MDA-MB-157 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.856159 THP1 DepMap CRISPR Gene Dependency 1.0 2.70535 lateral hypothalamic area, tuberal region, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.10276 medioventral part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.97066 POLR2A_H54_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Rectum adenocarcinoma_READ_TCGA-DC-6682-01A-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RT112 CCLE Cell Line Gene CNV Profiles 1.0 1.32925 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IM-01A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H1437 COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC9643473-Table1.xls-MAF_0_005-HGVS_gene_MAF Rummagene Transcription Factor Associations 2026 1.0 null polycystic ovary syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.751271 HCC1143 CCLE Cell Line Gene CNV Profiles 1.0 1.83575 PACADD188 DepMap CRISPR Gene Dependency 1.0 3.47225 NCI-H378 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCI-H345 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.42667 928 MEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.83347 HPAC CCLE Cell Line Gene CNV Profiles -1.0 -1.87269 SG in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.14365 CALU-6 COSMIC Cell Line Gene CNV Profiles -1.0 -2.91612 AR-25329375-VCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null NCI-H1666 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.71891 SHP77 CCLE Cell Line Gene CNV Profiles -1.0 -2.3516 outer SZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.859488 NCIH2122 CCLE Cell Line Gene CNV Profiles -1.0 -1.70769 LU-165 COSMIC Cell Line Gene Mutation Profiles 1.0 null cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 WIL2-NS COSMIC Cell Line Gene Mutation Profiles 1.0 null OVCAR-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.69479 Breast disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.237 HPAC Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.83425 choroid plexus of the lateral ventricle Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.3177 Thoracic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.236 Ovarian disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.422 LC-1-SQ COSMIC Cell Line Gene Mutation Profiles 1.0 null OV-90 COSMIC Cell Line Gene Mutation Profiles 1.0 null TNKS_INHIBITION_GDS5029_281_human_SW480 KRAS-mutant colorectal cancer cell line - 16hours GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null NCI-H889 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26096 Lung squamous cell carcinoma_LUSC_TCGA-56-8626-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KMS18 CCLE Cell Line Gene CNV Profiles 1.0 1.56152 EBNA2-21746931-IB4-LCL-HUMAN ChEA Transcription Factor Targets 2022 1.0 null ESR1_KD_GDS4065_452_human_MCF7 estrogen-sensitive breast cancer cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null WPE1NA22 DepMap CRISPR Gene Dependency 1.0 2.05185 UACC-257 COSMIC Cell Line Gene Mutation Profiles 1.0 null MPP89 DepMap CRISPR Gene Dependency 1.0 2.11022 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3427-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null OAW28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.31179 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5683-01A-11R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MEF2A JASPAR Predicted Transcription Factor Targets 1.0 null WM793B COSMIC Cell Line Gene Mutation Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GY-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NUGC-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0279 globose nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.24143 Adrenocortical carcinoma_ACC_TCGA-OR-A5LT-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null system GeneRIF Biological Term Annotations 1.0 null NCI-H2461 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.933162 intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M6-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HP-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9me3_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JA-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MIR34_OE_GDS2755_645_human_HCT116 cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null EGI1 DepMap CRISPR Gene Dependency 1.0 2.28957 HS 940.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09989 COR-L32 COSMIC Cell Line Gene Mutation Profiles 1.0 null isoforms GeneRIF Biological Term Annotations 1.0 null OVCAR8 CCLE Cell Line Gene CNV Profiles 1.0 1.44903 NCI-H1373 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.942928 upper limb region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.974056 SMAD4-21741376-EPCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null MDA-MB-435 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.58872 KURAMOCHI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.48484 NCI-H1651 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05019 SP in rostral midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.08044 CA46 COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC6187090-mmc1.xlsx-TP53_positive-Symbol_TP53 Rummagene Transcription Factor Associations 2026 1.0 null WM88 CCLE Cell Line Gene CNV Profiles 1.0 1.44353 cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 female reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056887 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6992-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-33-6738-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PCGF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99894 intermediate portion of DFC (area 9/46) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.934128 disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.03973 PMC12534504-41598_2025_20489_MOESM1_ESM.pdf-390-ZBTB46_ZBTB46 Rummagene Transcription Factor Associations 2026 1.0 null head of caudate Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.870902 RMND1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51445 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5177-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MPV17L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68554 GUCD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4847 Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GY-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H2171 COSMIC Cell Line Gene Mutation Profiles 1.0 null DMS-273 COSMIC Cell Line Gene Mutation Profiles 1.0 null MAPK1_knockdown_145_GSE31912 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.09925 KCIMOH1 CCLE Cell Line Gene CNV Profiles -1.0 -1.40525 NB69 DepMap CRISPR Gene Dependency 1.0 3.14561 Brain Lower Grade Glioma_LGG_TCGA-DB-A4XE-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SP in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.42757 posterior hypothalamic area, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.15423 outer CP in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.965546 FADU Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.01071 CAPAN-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.974818 OE19 COSMIC Cell Line Gene CNV Profiles 1.0 2.14731 syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.571107 lateral tuberal nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.0122 Cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.636 HEC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null BCL6-27268052-CHIP-SEQ-BCELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SNU1033 CCLE Cell Line Gene CNV Profiles 1.0 1.40803 testis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.478534 thyroid GTEx Tissue Gene Expression Profiles -1.0 -0.974287 HCC1569 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.903939 integument TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null DDX27 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.76455 A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc_7Hour_None_GSE43204 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.88427 primary GeneRIF Biological Term Annotations 1.0 null inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.03373 RL95-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null TF1 CCLE Cell Line Gene CNV Profiles -1.0 -1.60912 alitretinoin_homo sapiens_gpl6480_gse43090 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null D-283MED COSMIC Cell Line Gene Mutation Profiles 1.0 null TUG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89323 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IK-01A-12R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H1838 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18728 Malignant Neoplasm DisGeNET Gene-Disease Associations 1.0 null Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.52 NCI-H1792 COSMIC Cell Line Gene CNV Profiles -1.0 -2.91612 NCIH838 CCLE Cell Line Gene CNV Profiles -1.0 -1.52872 NCIH1694 CCLE Cell Line Gene CNV Profiles 1.0 1.61567 Esophagus - Gastroesophageal Junction GTEx Tissue Gene Expression Profiles 2023 1.0 7.21239 NDUFA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89741 NB5 DepMap CRISPR Gene Dependency 1.0 2.3577 Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A5W6-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null F36P CCLE Cell Line Gene CNV Profiles 1.0 2.30598 KM12 COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-78-7220-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pyramidal cells of rostral CA4 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.97487 G111 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.949273 GR-M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26096 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AG-06A-31R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EFM-192B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.832758 NBR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36612 posterior orbital gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.17471 cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null HS 766T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.58932 MOLT-16 COSMIC Cell Line Gene Mutation Profiles 1.0 null CHSA8926 COSMIC Cell Line Gene Mutation Profiles 1.0 null RH-41 COSMIC Cell Line Gene Mutation Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DB-A4XH-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MEL-JUSO COSMIC Cell Line Gene Mutation Profiles 1.0 null ES8 DepMap CRISPR Gene Dependency 1.0 5.34296 Prostate Carcinoma DisGeNET Gene-Disease Associations 1.0 null Gastrointestinal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.187 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TC-01A-21R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null semen TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.509813 Prostate cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.26 PK-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.19228 HCC461 DepMap CRISPR Gene Dependency 1.0 3.72925 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GM-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HS863T CCLE Cell Line Gene CNV Profiles 1.0 1.47769 A-CA-04-2009(H1N1)_18Hour_None_GSE37571 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.94805 MOLM-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00487 LUDLU1 CCLE Cell Line Gene CNV Profiles -1.0 -1.58263 PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-ENSEMBL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null superficial layers of caudal presubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.17197 IZ in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.32737 NCI-N417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.834612 NCIH522 CCLE Cell Line Gene CNV Profiles 1.0 1.36184 CX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.903996 HCC1359 DepMap CRISPR Gene Dependency 1.0 2.07422 TCF3/E2A-22897851-JUKARTE6-1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null HEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.48484 OV7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.998934 animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GEO COSMIC Cell Line Gene Mutation Profiles 1.0 null MEK_INHIBITION_GDS5029_278_human_SW480 KRAS-mutant colorectal cancer cell line - 4hours GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null HN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00699 magnocellular division of VA Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.825175 spermatogenesis GeneRIF Biological Term Annotations 1.0 null CMK115 CCLE Cell Line Gene CNV Profiles 1.0 1.84286 NDUFV2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.73625 ST486 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCI-H1793 COSMIC Cell Line Gene Mutation Profiles 1.0 null ES6 COSMIC Cell Line Gene Mutation Profiles 1.0 null SNU-C2B COSMIC Cell Line Gene Mutation Profiles 1.0 null COLO-783 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18836 preoptic region, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.63828 Colorectal cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.113 organelle LOCATE Predicted Protein Localization Annotations 1.0 null PMC9643473-Table1.xls-MAF_0_005-Gene_refGenecanonical_MAF Rummagene Transcription Factor Associations 2026 1.0 null rostral division of OFCi (area 11) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.29283 membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051139 internal male genital organ TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null SG in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.834703 Large intestine cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.112 plasma membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 KLF17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5716 KYSE520 CCLE Cell Line Gene CNV Profiles -1.0 -1.45084 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MV-06A-11R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TGBC11TKB COSMIC Cell Line Gene Mutation Profiles 1.0 null H2803 COSMIC Cell Line Gene Mutation Profiles 1.0 null spermatocytes GeneRIF Biological Term Annotations 1.0 null NB17 DepMap CRISPR Gene Dependency 1.0 9.32919 Ovarian Neoplasm DisGeNET Gene-Disease Associations 1.0 null NCI-H522 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.928274 doxorubicin_homo sapiens_gpl6947_gse25741 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.03975 Ankylosing Spondylitides_macrophage_GSE11886 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.40225 H3K9me3_Peripheral Blood Mononuclear Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null TCF3 ENCODE Transcription Factor Targets 1.0 null SG in primary auditory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.00107 FADU CCLE Cell Line Gene CNV Profiles -1.0 -1.57065 NCI-H835 COSMIC Cell Line Gene Mutation Profiles 1.0 null SNU-387 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0279 MCC13 COSMIC Cell Line Gene Mutation Profiles 1.0 null HCC827 CCLE Cell Line Gene CNV Profiles 1.0 1.47197 A-Vietnam-1203-2004(H5N1)_24Hour_None_GSE43204 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.78634 Acute Myeloid Leukemia_LAML_TCGA-AB-3011-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Edinger-Westphal nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.16104 globus pallidus, external segment, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.999123 Lung squamous cell carcinoma_LUSC_TCGA-92-7340-01A-21R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null gracile nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.22703 cuneiform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.00392 NCI-H2081 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.869245 PL18 COSMIC Cell Line Gene Mutation Profiles 1.0 null M059K DepMap CRISPR Gene Dependency 1.0 2.54413 BICR10 DepMap CRISPR Gene Dependency 1.0 3.56048 TMEM14C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.85943 female reproductive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.061585 whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null NCIH1781 CCLE Cell Line Gene CNV Profiles 1.0 1.57275 dorsomedial hypothalamic nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.2496 CDK4_knockdown_133_GSE31534 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.59835 parataenial nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.910446 Female reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.354 HDQP1 CCLE Cell Line Gene CNV Profiles 1.0 1.59841 PF-382 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCI-H64 COSMIC Cell Line Gene Mutation Profiles 1.0 null gonad TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.451428 Liver hepatocellular carcinoma_LIHC_TCGA-BW-A5NO-01A-11R-A27V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null medial habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.1702 gigantocellular reticular nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.18361 Prostate adenocarcinoma_PRAD_TCGA-VN-A88O-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC2450 DepMap CRISPR Gene Dependency 1.0 5.07574 NCI-H196 COSMIC Cell Line Gene CNV Profiles -1.0 -2.91612 supraoptic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.855451 NO10 DepMap CRISPR Gene Dependency 1.0 5.20196 NKX2-6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.09811 HCC70 DepMap CRISPR Gene Dependency 1.0 2.02968 T24 DepMap CRISPR Gene Dependency 1.0 6.64295 COV504 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.974818 Uterine Carcinosarcoma_UCS_TCGA-N5-A4RT-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-BC-4073-01B-02R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EVSA-T COSMIC Cell Line Gene Mutation Profiles 1.0 null CTCF_LNCaP clone FGC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KMS-26 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.25415 MG-63 COSMIC Cell Line Gene Mutation Profiles 1.0 null SK-MEL-28 COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-SYMBOL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null HCC202 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.9086 basal ventral medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.931487 NCIN87 CCLE Cell Line Gene CNV Profiles -1.0 -1.35656 GTF2H5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76924 OE21 CCLE Cell Line Gene CNV Profiles -1.0 -1.43709 SESN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.93288 SPI1-20517297-HL60-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null SNU81 DepMap CRISPR Gene Dependency 1.0 9.49022 infertility DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.727333 HCC1534 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.7081 rostral ventral respiratory cell group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.1886 cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 KCI-MOH1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.7398 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4981-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051139 NCI-H526 COSMIC Cell Line Gene Mutation Profiles 1.0 null HCC4011 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.30823 EBNA2-21746931-IB4-LCL-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null OVCAR-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15448 D-392MG COSMIC Cell Line Gene Mutation Profiles 1.0 null MKN-74 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.32464 TGBC1TKB COSMIC Cell Line Gene CNV Profiles -1.0 -2.91612 Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-4104-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null male reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null HS766T CCLE Cell Line Gene CNV Profiles -1.0 -1.32539 P30-OHK COSMIC Cell Line Gene Mutation Profiles 1.0 null Endocrine system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.371 NCI-H847 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.846636 characterized GeneRIF Biological Term Annotations 1.0 null UMUC3 DepMap CRISPR Gene Dependency 1.0 4.0018 Heart sarcoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.342 TALL1 CCLE Cell Line Gene CNV Profiles 1.0 1.97016 A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB1-F2del_12Hour_None_GSE43203 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.06814 multiform (lateral) division of MD Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.43425 KPNYS DepMap CRISPR Gene Dependency 1.0 3.88348 Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.634 BB30-HNC COSMIC Cell Line Gene Mutation Profiles 1.0 null MC-IXC COSMIC Cell Line Gene Mutation Profiles 1.0 null implying GeneRIF Biological Term Annotations 1.0 null molecular layer of rostral subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.29908 CTBP1-25329375-LNCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null lingual gyrus, left, striate Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.03234 Prostate adenocarcinoma_PRAD_TCGA-EJ-5505-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-7_DEGs_USF2-KO_vs_control-Gene_Symbol_USF2 Rummagene Transcription Factor Associations 2026 1.0 null TCCPAN2 CCLE Cell Line Gene CNV Profiles -1.0 -2.67354 MMAC-SF COSMIC Cell Line Gene Mutation Profiles 1.0 null Mesothelioma_MESO_TCGA-LK-A4NZ-01A-12R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cingulum bundle, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.1484 ZR-75-30 COSMIC Cell Line Gene Mutation Profiles 1.0 null AGS COSMIC Cell Line Gene Mutation Profiles 1.0 null NCI-H2342 COSMIC Cell Line Gene Mutation Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19H-06A-12R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null male reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Ovary epithelial cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.055 Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SQ1 CCLE Cell Line Gene CNV Profiles -1.0 -1.6962 Reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.463 NCIH1792 CCLE Cell Line Gene CNV Profiles -1.0 -2.12864 SK-HEP-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null parolfactory gyri, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.997852 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A49A-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LOX-IMVI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.855004 Lung squamous cell carcinoma_LUSC_TCGA-63-A5MW-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SCC-9 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.847557 NCI-H2030 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.998934 Ovarian cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.433 Lung cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.194 Respiratory system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.183 inner CP in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.866515 BL2882 (CHEK2) NURSA Protein Complexes 1.0 null Prostate disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.258 Developmental dysplasia of the hip DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.212 Prostate adenocarcinoma_PRAD_TCGA-CH-5767-01A-11R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null outer CP in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.41758 Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4TZ-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H2023 COSMIC Cell Line Gene Mutation Profiles 1.0 null outer SZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.881366 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4975-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.08155 apoptosis GeneRIF Biological Term Annotations 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41P-01A-12R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null midline nuclear complex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.99599 MKN-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.79837 inferior frontal gyrus, triangular part, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.02787 INAFM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15089 pote GeneRIF Biological Term Annotations 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A411-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-78-7155-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SP in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.943864 breast GTEx Tissue Gene Expression Profiles 1.0 1.66091 NCIH2106 CCLE Cell Line Gene CNV Profiles 1.0 1.35694 periventricular nucleus, preoptic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.73855 JUN-26020271-SMOOTH-MUSCLE-HUMAN ChEA Transcription Factor Targets 2022 1.0 null HCC1143 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.00944 NCI-H740 COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4973-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KINGS1 DepMap CRISPR Gene Dependency 1.0 3.46135 CALU6 CCLE Cell Line Gene CNV Profiles -1.0 -2.15786 CTCF_GM13976_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDA-MB-468 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.30961 PMC8185471-mmc4.xlsx-D4-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_4_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15 Rummagene Transcription Factor Associations 2026 1.0 null LP-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null medial habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.58388 outer CP in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.03278 JHH-6 COSMIC Cell Line Gene CNV Profiles 1.0 2.14731 Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41N-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4967-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 639-V COSMIC Cell Line Gene Mutation Profiles 1.0 null YMB-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00487 Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7370-01A-11R-2132-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null paraventricular nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.38599 NCI-H1581 COSMIC Cell Line Gene Mutation Profiles 1.0 null immunohistochemistry GeneRIF Biological Term Annotations 1.0 null NCI-N87 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.10689 inferior frontal gyrus, opercular part, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.17744 NCI-H2110 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.66674 perifornical nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.10568 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.36579 MOLP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.85579 Prostate adenocarcinoma_PRAD_TCGA-EJ-8468-01A-21R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MORCPR DepMap CRISPR Gene Dependency 1.0 2.22779 Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4223-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HT-144 COSMIC Cell Line Gene Mutation Profiles 1.0 null outer CP in (rostral) midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.72617 NCI-H2106 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.33458 suggests GeneRIF Biological Term Annotations 1.0 null male reproductive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.294939 CAR-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 3.19301 cingulate gyrus, frontal part, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.980466 polysensory temporal cortex (area 22p) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 3.34509 XKR8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99473 SW156 COSMIC Cell Line Gene Mutation Profiles 1.0 null JHU029 DepMap CRISPR Gene Dependency 1.0 3.93889 Epithelial Ovarian Cancer DisGeNET Gene-Disease Associations 1.0 null TBX10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29233 Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A3WV-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61I-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SKM-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null IPO8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9802 Lung adenocarcinoma_LUAD_TCGA-69-8255-01A-11R-2287-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MCF 10A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.29121 NCI-H510A COSMIC Cell Line Gene Mutation Profiles 1.0 null lateral parabrachial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.52509 interstitial nucleus of Cajal, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.39393 cochlear nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.67933 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1AD-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Intestinal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.094 Lung squamous cell carcinoma_LUSC_TCGA-66-2768-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNG-M COSMIC Cell Line Gene Mutation Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6488-01A-12R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null fastigial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.25808 HCC827 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26096 COLO679 DepMap CRISPR Gene Dependency 1.0 3.17117 CEBPB-22108803-LS180-HUMAN ChEA Transcription Factor Targets 2022 1.0 null external granular (germinal) layer of lower rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.867924 PANC 03.27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.903939 SUM 1315M02 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.40427 VMRC-LCD COSMIC Cell Line Gene Mutation Profiles 1.0 null raphe obscurus nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.931613 NCI-H1792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.50294 BEN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.85209 GRANTA519 CCLE Cell Line Gene CNV Profiles 1.0 2.12447 TCC-PAN2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.903458 frontal operculum, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.10845 SK-N-DZ COSMIC Cell Line Gene Mutation Profiles 1.0 null Polyarteritis Nodosa DisGeNET Gene-Disease Associations 1.0 null Carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.219 Retinitis pigmentosa 6 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.454 lingual gyrus, right, striate Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.905623 Head and Neck squamous cell carcinoma_HNSC_TCGA-UP-A6WW-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JURKAT COSMIC Cell Line Gene Mutation Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A8AZ-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TCF3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null frontal pole, left, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.50068 inner CP in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.38447 reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.061246 temporal pole, right, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.954099 interpeduncular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.02946 UBC Pathway Commons Protein-Protein Interactions 1.0 null KYSE-520 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.7398 MC116 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22352 A-Netherlands-602-2009(H1N1)_18Hour_None_GSE40844 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.90409 internal female genital organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053119 Prostate adenocarcinoma_PRAD_TCGA-2A-A8W1-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.64 SHP-77 COSMIC Cell Line Gene CNV Profiles -1.0 -2.91612 Lung squamous cell carcinoma_LUSC_TCGA-56-A49D-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LS-513 COSMIC Cell Line Gene Mutation Profiles 1.0 null MSTO-211H COSMIC Cell Line Gene Mutation Profiles 1.0 null OVISE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05019 arcuate nucleus of the hypothalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.970243 Prostate adenocarcinoma_PRAD_TCGA-J9-A8CL-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SCC-25 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1285 JJN-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null RL952 CCLE Cell Line Gene CNV Profiles 1.0 1.3389 Brain Lower Grade Glioma_LGG_TCGA-S9-A7R3-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H1155 COSMIC Cell Line Gene Mutation Profiles 1.0 null RKO COSMIC Cell Line Gene Mutation Profiles 1.0 null paraventricular nuclei, left of thalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.99863 ventromedial hypothalamic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.32982 CL-34 COSMIC Cell Line Gene Mutation Profiles 1.0 null intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null HCC1428 COSMIC Cell Line Gene Mutation Profiles 1.0 null HT-29 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.903996 SCC-15 COSMIC Cell Line Gene Mutation Profiles 1.0 null SBC-5 COSMIC Cell Line Gene Mutation Profiles 1.0 null gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null outer CP in granular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.1069 ICC8 DepMap CRISPR Gene Dependency 1.0 3.0461 RBPJ ChEA Transcription Factor Targets 1.0 null NCIH196 CCLE Cell Line Gene CNV Profiles -1.0 -2.83425 A-CA-04-2009(H1N1)_24Hour_None_GSE40844 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.64661 X, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.89699 MAX JASPAR Predicted Transcription Factor Targets 1.0 null MKN74 CCLE Cell Line Gene CNV Profiles -1.0 -1.52758 NCI-H2110 COSMIC Cell Line Gene Mutation Profiles 1.0 null FOXL1 JASPAR Predicted Transcription Factor Targets 1.0 null CDK8_knockdown_147_GSE32108 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.5289 H513 COSMIC Cell Line Gene Mutation Profiles 1.0 null ovary TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.350743 ECC12 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K9me3_fibroblast of lung_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4P0-01A-41R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EW22 DepMap CRISPR Gene Dependency 1.0 2.47665 anterior hypothalamic area, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.41698 RPMI-8226 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K9me3_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null KHM-1B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.85209 KARPAS-45 COSMIC Cell Line Gene Mutation Profiles 1.0 null Male reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.29 TE5 CCLE Cell Line Gene CNV Profiles -1.0 -1.51213 NALM-6 COSMIC Cell Line Gene Mutation Profiles 1.0 null SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null YAMATO DepMap CRISPR Gene Dependency 1.0 4.34589 NFKB1 JASPAR Predicted Transcription Factor Targets 1.0 null lateral group of nuclei, right, ventral division Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.858633 KURAMOCHI COSMIC Cell Line Gene Mutation Profiles 1.0 null anterior orbital gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.14554 SG in dysgranular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.860368 ZBTB33 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66627 P300-19829295-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null NCI-H358 COSMIC Cell Line Gene Mutation Profiles 1.0 null LS411N DepMap CRISPR Gene Dependency 1.0 3.12028 U251MG DepMap CRISPR Gene Dependency 1.0 5.91702 MINPP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15663 ESO51 COSMIC Cell Line Gene Mutation Profiles 1.0 null CMK CCLE Cell Line Gene CNV Profiles 1.0 1.5871 OE19 CCLE Cell Line Gene CNV Profiles 1.0 2.24465 lateral orbital frontal cortex (area 12/47) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.83493 SMAD3-21741376-EPCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Male reproductive organ cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.293 COLO320 CCLE Cell Line Gene CNV Profiles -1.0 -1.7266 Lung squamous cell carcinoma_LUSC_TCGA-56-A4ZK-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null subparafascicular nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.54777 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7418-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null principal sensory nucleus of trigeminal nerve, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.927628 NCI-H2122 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.58872 BEN CCLE Cell Line Gene CNV Profiles 1.0 1.67727 Prostate adenocarcinoma_PRAD_TCGA-YL-A8SH-01B-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SG in caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.07437 inner SZ in midlateral extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.901156 Lung squamous cell carcinoma_LUSC_TCGA-90-A4ED-01A-31R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NEUROG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85637 Polyarteritis Nodosa, Childhood-Onset DisGeNET Gene-Disease Associations 1.0 null reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null MES-SA COSMIC Cell Line Gene Mutation Profiles 1.0 null KPL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08609 Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A623-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-34-5927-01A-11R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SPI1 ChEA Transcription Factor Targets 1.0 null nucleus accumbens, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.976524 membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null NCI-H2052 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18836 JHH-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null DKMG DepMap CRISPR Gene Dependency 1.0 3.92873 Lung squamous cell carcinoma_LUSC_TCGA-56-7731-01A-11R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null midbrain reticular formation Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.0969 PL45 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.03446 A-Netherlands-602-2009(H1N1)_24Hour_None_GSE40844 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.50044 Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3I3-06A-11R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FAM156B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.02947 VIIB, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.839189 Skin Cutaneous Melanoma_SKCM_TCGA-GN-A265-06A-21R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A3MG-01A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H2135 COSMIC Cell Line Gene Mutation Profiles 1.0 null SULT1C4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.02975 JHH-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.832758 COLO 320DM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.43185 Prostate adenocarcinoma_PRAD_TCGA-EJ-A65E-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC-366 COSMIC Cell Line Gene Mutation Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9RE-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EJ-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION ChEA Transcription Factor Targets 2022 1.0 null tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051008 cell part LOCATE Predicted Protein Localization Annotations 1.0 null NCI-H1838 COSMIC Cell Line Gene Mutation Profiles 1.0 null DMS-53 COSMIC Cell Line Gene Mutation Profiles 1.0 null PA-TU-8902 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -3.52744 paraventricular nucleus of the hypothalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.4335 MN-60 COSMIC Cell Line Gene Mutation Profiles 1.0 null SOX7_OE_GDS3300_123_human_HESC (CA1 and CA2) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null UM-UC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.12764 MEWO COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-85-A512-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null motor nucleus of trigeminal nerve, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.847004 SW1271 COSMIC Cell Line Gene Mutation Profiles 1.0 null Reproductive organ cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.483 urogenital system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.058314 KNS-62 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.52011 Lung squamous cell carcinoma_LUSC_TCGA-77-7142-01A-11R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1599 CCLE Cell Line Gene CNV Profiles 1.0 1.53517 Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E8-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7915-01A-11R-2204-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5E-Down_H3K27me3_DPY30_KD-Unnamed_12_AR Rummagene Transcription Factor Associations 2026 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-K7-AAU7-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KYO1 CCLE Cell Line Gene CNV Profiles 1.0 1.96698 inferior olive, principal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.926186 REH COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC7794364-41540_2020_161_MOESM3_ESM.xlsx-NSP_Unique_-_PPH2_predictions-Gene_Sym_SMAD9 Rummagene Transcription Factor Associations 2026 1.0 null cell periphery COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 PMC4823830-ncomms11171-s4.xlsx-high_in_shRNA_GATA3-GeneSymbol_GATA3 Rummagene Transcription Factor Associations 2026 1.0 null C33A DepMap CRISPR Gene Dependency 1.0 2.44784 MHH-PREB-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.38021 Lung adenocarcinoma_LUAD_TCGA-O1-A52J-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null posterior hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.73409 Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q4-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SLC45A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.89689 BICR22 COSMIC Cell Line Gene Mutation Profiles 1.0 null RT-112 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.30289 SUDHL10 DepMap CRISPR Gene Dependency 1.0 3.32618 KIF26A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.1466 Gastrointestinal system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.166 H4 COSMIC Cell Line Gene Mutation Profiles 1.0 null rostral (anterior) extramural migratory stream Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.957725 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3J8-06A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KM12 CCLE Cell Line Gene CNV Profiles -1.0 -1.34829 fallopian tube GTEx Tissue Gene Expression Profiles -1.0 -1.29873 LMX1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46887 tuberomammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.888677 Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A0C8-01A-11R-A10U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.061 Breast cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.24 LS1034 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.869245 H3K9me3_Brain Germinal Matrix Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.511