association dataset threshold value standardized value Flagellum attachment zone COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.356 inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.94896 Lung squamous cell carcinoma_LUSC_TCGA-85-8287-01A-11R-2296-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CPT1A Pathway Commons Protein-Protein Interactions 1.0 null Brain Lower Grade Glioma_LGG_TCGA-QH-A6CV-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VEZF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.1414 hippocampus (hippocampal formation)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.87808 SEPT9 Pathway Commons Protein-Protein Interactions 1.0 null RPS8 Pathway Commons Protein-Protein Interactions 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A69Q-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NP-69 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.195 POLR2A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FPGS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27672 GSE188570,GSE188571_3_v_4_decitabine_human RummaGEO Drug Perturbation Signatures 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44O-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null la4 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.527 LDHB Pathway Commons Protein-Protein Interactions 1.0 null CUL3 Pathway Commons Protein-Protein Interactions 1.0 null ALDH1B1 Pathway Commons Protein-Protein Interactions 1.0 null CFL1 Pathway Commons Protein-Protein Interactions 1.0 null inner CP in ventromedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.912182 parasolitary nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.40624 Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3RC-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IST-SL2 COSMIC Cell Line Gene Mutation Profiles 1.0 null COPA Pathway Commons Protein-Protein Interactions 1.0 null (S)-(-)-Pindolol DeepCoverMOA Drug Mechanisms of Action 1.0 0.25 TOV-112D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.962829 JL1 CCLE Cell Line Gene CNV Profiles 1.0 1.4736 Lung adenocarcinoma_LUAD_TCGA-05-4402-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100337_HIP_possible Alzheimer's disease_no TBI_100+_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.091 Acute Myeloid Leukemia_LAML_TCGA-AB-2916-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Whole body TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 YBX3 Pathway Commons Protein-Protein Interactions 1.0 null CTCF_skin fibroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Nasopharyngeal cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.999 inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.06103 Lung adenocarcinoma_LUAD_TCGA-95-7562-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A857-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null laterodorsal subdivision of area 8 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.27517 SP in midlateral extrastriate cortex (area 19) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.839969 periaqueductal gray substance, ventral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.843575 Respiratory system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.131 ZNF280D Pathway Commons Protein-Protein Interactions 1.0 null Elytron TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.682 NFYC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.0457 TUBB Pathway Commons Protein-Protein Interactions 1.0 null MAC2A DepMap CRISPR Gene Dependency 1.0 2.46857 BEN CCLE Cell Line Gene CNV Profiles 1.0 1.68863 Kidney Chromophobe_KICH_TCGA-KN-8432-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UACC-812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.894471 GSE175787_4_v_10_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7068-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE148657_3_v_1_cd44_human RummaGEO Gene Perturbation Signatures 1.0 null MI-773 DeepCoverMOA Drug Mechanisms of Action 1.0 1.16 NCI-H187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23986 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A5UE-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PTPN9 Pathway Commons Protein-Protein Interactions 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DH-5140-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CFP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69619 RQCD1 Pathway Commons Protein-Protein Interactions 1.0 null BEN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.46674 primary auditory cortex (core)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.844606 GSE108500_1_v_0_foxp1_human RummaGEO Gene Perturbation Signatures 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-8563-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FAM110A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.85716 PMC9526582__F2 PFOCR Pathway Figure Associations 2024 1.0 null HK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81977 Scutellum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.503 Photoreceptor outer segment membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.877 PRPF4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29125 DUX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.8533 DDX20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6159 A-CA-04-2009(H1N1)_0Hour_None_GSE37571 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.77251 RANBP1 Pathway Commons Protein-Protein Interactions 1.0 null 496100469_TCx_no dementia_TBI_89_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.93379 BARX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.06207 PMC12289921-41467_2025_62099_MOESM5_ESM.xlsx-MI-2-80-Gene_Symbol_MITF Rummagene Transcription Factor Associations 2026 1.0 null CKAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45398 Lung adenocarcinoma_LUAD_TCGA-55-8204-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SBC5 CCLE Cell Line Gene CNV Profiles 1.0 1.91522 Lung squamous cell carcinoma_LUSC_TCGA-O2-A52N-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null WDR62 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.74021 SK-MES-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null RPL37A Pathway Commons Protein-Protein Interactions 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-6397-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Biofilm matrix COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.782 GSE216043_11_v_5_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null NVT complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.718 Signaling by Rho GTPases Reactome Pathways 2024 1.0 null DDHD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67607 Sarcoma_SARC_TCGA-3B-A9HR-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NFYA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.8228 Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.466 Lung squamous cell carcinoma_LUSC_TCGA-63-A5MW-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PYGL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48182 PCCB Pathway Commons Protein-Protein Interactions 1.0 null CHD4 Pathway Commons Protein-Protein Interactions 1.0 null EPLC-272H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14873 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BM-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ACTB Pathway Commons Protein-Protein Interactions 1.0 null GCN1L1 Pathway Commons Protein-Protein Interactions 1.0 null primary auditory cortex (core)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.943318 PCMT1 Pathway Commons Protein-Protein Interactions 1.0 null posteroventral (inferior) parietal cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.867981 SGPL1 Pathway Commons Protein-Protein Interactions 1.0 null TMEM109 Pathway Commons Protein-Protein Interactions 1.0 null NCIH810 CCLE Cell Line Gene CNV Profiles 1.0 2.71672 Lung squamous cell carcinoma_LUSC_TCGA-O2-A52Q-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ARL1 Pathway Commons Protein-Protein Interactions 1.0 null Lung adenocarcinoma_LUAD_TCGA-78-7160-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.15918 HIST1H2BK Pathway Commons Protein-Protein Interactions 1.0 null A-CA-04-2009(H1N1)_36Hour_None_GSE37571 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.27003 JJN-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00483 Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-7268-01A-11R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DRG1 Pathway Commons Protein-Protein Interactions 1.0 null GATA2 JASPAR Predicted Transcription Factor Targets 1.0 null HCT-15 COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC6961462-NIHMS1544104-supplement-Sup_Tab.xlsx-Sup_Table_3_a-Supplementary_Table_3_Genes_Regulated_by_A_MYB_in_Humans_and_Macaques_Bold_genes_with_reduced_expression_in_Group_3_MYB Rummagene Transcription Factor Associations 2026 1.0 null N4BP2L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89074 Signal Transduction Reactome Pathways 2024 1.0 null T-47D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00483 STEAP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3331 UROD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66679 HCT-116 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.675 RPLP1 Pathway Commons Protein-Protein Interactions 1.0 null choroid plexus of the fourth ventricle Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.25726 MEK2 Kinase Library Serine Threonine Kinome Atlas 1.0 null UBC Pathway Commons Protein-Protein Interactions 1.0 null FHOD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37771 Uterine Carcinosarcoma_UCS_TCGA-N5-A4RO-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF552 Pathway Commons Protein-Protein Interactions 1.0 null 6-Aminochrysene DeepCoverMOA Drug Mechanisms of Action -1.0 -0.46 GSE182179_2_v_4_kdsr_human RummaGEO Gene Perturbation Signatures -1.0 null LDN-192960 DeepCoverMOA Drug Mechanisms of Action 1.0 0.45 BMI1 Pathway Commons Protein-Protein Interactions 1.0 null extracellular membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null HCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.984438 NSL1 Pathway Commons Protein-Protein Interactions 1.0 null SFXN1 Pathway Commons Protein-Protein Interactions 1.0 null axon GO Cellular Component Annotations 2025 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A5W8-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RIGI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11081 HSPD1 Pathway Commons Protein-Protein Interactions 1.0 null GSE245778_1_v_0_runx1_human RummaGEO Gene Perturbation Signatures -1.0 null PLLP Pathway Commons Protein-Protein Interactions 1.0 null CBX5 Pathway Commons Protein-Protein Interactions 1.0 null inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.26041 COPB2 Pathway Commons Protein-Protein Interactions 1.0 null NCI-H2804 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.984438 MCCC2 Pathway Commons Protein-Protein Interactions 1.0 null RPL31 Pathway Commons Protein-Protein Interactions 1.0 null NCI-H1092 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13502 GSE226249_2_v_4_pirfenidone_human RummaGEO Drug Perturbation Signatures -1.0 null ETCC016 DepMap CRISPR Gene Dependency 1.0 2.08571 GSE162892_4_v_5_isox_human RummaGEO Drug Perturbation Signatures -1.0 null PRKDC Pathway Commons Protein-Protein Interactions 1.0 null posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.954841 GBAS Pathway Commons Protein-Protein Interactions 1.0 null SEPT11 Pathway Commons Protein-Protein Interactions 1.0 null Sarcoma_SARC_TCGA-DX-A2J0-01A-11R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.41842 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GO-06A-12R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SRA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.12231 protein kinase binding GO Molecular Function Annotations 2023 1.0 null GSE185744,GSE185747_0_v_3_sox9_human RummaGEO Gene Perturbation Signatures -1.0 null primary motor cortex (area M1, area 4)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -3.15477 hippocampus (hippocampal formation)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.28955 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6B0-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DNM2 Pathway Commons Protein-Protein Interactions 1.0 null PRDM1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.5362 NCI-H146 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.48347 NCI-H920 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.10845 PGAM1 Pathway Commons Protein-Protein Interactions 1.0 null GSE168604,GSE183859_1_v_0_selumetinib_human RummaGEO Drug Perturbation Signatures 1.0 null KMRC2 DepMap CRISPR Gene Dependency 1.0 2.36054 Luteal cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.736 ATXN2L Pathway Commons Protein-Protein Interactions 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.8501 HLA-B Pathway Commons Protein-Protein Interactions 1.0 null HIST1H2AJ Pathway Commons Protein-Protein Interactions 1.0 null CHD5 Pathway Commons Protein-Protein Interactions 1.0 null B3GAT3 Pathway Commons Protein-Protein Interactions 1.0 null HLF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.9084 neuron projection GO Cellular Component Annotations 2025 1.0 null ATE1 Pathway Commons Protein-Protein Interactions 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-8106-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6826-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE238116_3_v_0_egr1_human RummaGEO Gene Perturbation Signatures 1.0 null granular layer of rostral dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.80483 HNRNPUL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99017 CAL148 CCLE Cell Line Gene CNV Profiles -1.0 -2.15241 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6941-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.142 SW900 CCLE Cell Line Gene CNV Profiles 1.0 1.42833 ASK1 Kinase Library Serine Threonine Kinome Atlas 1.0 null cerebellar cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.40974 Lung adenocarcinoma_LUAD_TCGA-78-7150-01A-21R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null corpus callosum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.54061 neuron projection morphogenesis GO Biological Process Annotations 2025 1.0 null CDH1 Pathway Commons Protein-Protein Interactions 1.0 null posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.05672 NCI-H2198 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.984438 A-CA-04-2009(H1N1)_24Hour_None_GSE40844 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.61075 CAL-148 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.93686 BHY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.950178 PMC7415402-oncotarget-11-2995-s004.xlsx-EWS-FLI1_Type_2_vs_Type_3-Gene_Symbol_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null Rectum adenocarcinoma_READ_TCGA-CL-5918-01A-11R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE210682_2_v_1_methadone_human RummaGEO Drug Perturbation Signatures -1.0 null SLC49A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20887 Prostate adenocarcinoma_PRAD_TCGA-EJ-7789-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ITGB4 Pathway Commons Protein-Protein Interactions 1.0 null MEL270 DepMap CRISPR Gene Dependency 1.0 2.72585 KMS20 DepMap CRISPR Gene Dependency 1.0 2.03105 PCDH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77052 COLO 853 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.2059 496100597_HIP_dementia_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.03522 GFI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.0802 H3K36me3_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CAPZA1 Pathway Commons Protein-Protein Interactions 1.0 null RIMS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36719 Perturb_7886_OE_SRSF10_SRP303822 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JC-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Carcinogenesis DisGeNET Gene-Phenotype Associations 1.0 null KLF13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.8645 outer SZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 3.34509 PMC12956708-DataSheet1.xlsx-Supplementary_Table_7-Supplementary_Table_6_The_DEGs_from_high_altitude_between_AMS_and_non-eAMS_group_of_GSE75665_TWIST2 Rummagene Transcription Factor Associations 2026 1.0 null Brain Lower Grade Glioma_LGG_TCGA-E1-5303-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SG in posterior frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.72578 RPS13 Pathway Commons Protein-Protein Interactions 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HF-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-1200 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 TPD52L2 Pathway Commons Protein-Protein Interactions 1.0 null PHGDH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1751 Lung squamous cell carcinoma_LUSC_TCGA-63-7022-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC9533694-MOL2-16-3410-s013.xlsx-FIR20vsREST_DEMs-FIR20_vs_REST_DEMs_Down_REST Rummagene Transcription Factor Associations 2026 1.0 null GSE158182_5_v_7_pnpla3_human RummaGEO Gene Perturbation Signatures -1.0 null RPL30 Pathway Commons Protein-Protein Interactions 1.0 null OV7 DepMap CRISPR Gene Dependency 1.0 2.83454 GSE242290_3_v_0_glutathione_human RummaGEO Drug Perturbation Signatures 1.0 null MYH14 Pathway Commons Protein-Protein Interactions 1.0 null EDF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39992 RPL7A Pathway Commons Protein-Protein Interactions 1.0 null COPB1 Pathway Commons Protein-Protein Interactions 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-CC-5263-01A-01R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TCF4-23295773-U87-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-J9-A8CL-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null medial mammillary nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.1981 mediodorsal nucleus of thalamus_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.06567 PABPC1 Pathway Commons Protein-Protein Interactions 1.0 null DNAJC24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46276 amygdaloid complex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.926722 POLR2A_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ITGB1 Pathway Commons Protein-Protein Interactions 1.0 null CSE1L Pathway Commons Protein-Protein Interactions 1.0 null U-2 OS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.28978 Cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.537 NCIH2291 CCLE Cell Line Gene CNV Profiles 1.0 1.4374 Lung adenocarcinoma_LUAD_TCGA-44-2662-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UCHL5 Pathway Commons Protein-Protein Interactions 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NH-01A-12R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5882-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-E1-5302-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Primary cutaneous amyloidosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.004 EHD4 Pathway Commons Protein-Protein Interactions 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2833-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7413-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Granular vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.586 POTEJ Pathway Commons Protein-Protein Interactions 1.0 null CBX1 Pathway Commons Protein-Protein Interactions 1.0 null PRKCSH Pathway Commons Protein-Protein Interactions 1.0 null PMC10243915-uxad037_suppl_supplementary_table_s1a.pdf-499-SPDEF_SPDEF Rummagene Transcription Factor Associations 2026 1.0 null FANCI Pathway Commons Protein-Protein Interactions 1.0 null MDA-MB-330 COSMIC Cell Line Gene CNV Profiles -1.0 -5.12655 PMC12271601-mmc2.xlsx-OUT_cells_03-Gene_Symbol_TCF23 Rummagene Transcription Factor Associations 2026 1.0 null PMC9248879-supp_gr.275831.121_Supplemental_Table_S2.xlsx-TP53-dependent_proteins-GeneName_TP53 Rummagene Transcription Factor Associations 2026 1.0 null Mesothelioma_MESO_TCGA-NQ-A57I-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KMS-26 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.50222 U-2932 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.80348 testis_7e HPA Tissue Sample Gene Expression Profiles 1.0 1.4093 PMC11749115-loae020_suppl_Supplementary_Table_S2.xlsx-CHOP-high-gene_DDIT3 Rummagene Transcription Factor Associations 2026 1.0 null HIST1H2AB Pathway Commons Protein-Protein Interactions 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6221-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DB-5281-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B7-01A-31R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intercalated nucleus of medulla Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.47682 NPM1 Pathway Commons Protein-Protein Interactions 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-63-7020-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.28315 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3J4-06A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE211151_1_v_0_progesterone_human RummaGEO Drug Perturbation Signatures -1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-ED-A5KG-01A-11R-A27V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RPS6 Pathway Commons Protein-Protein Interactions 1.0 null HIST1H2BL Pathway Commons Protein-Protein Interactions 1.0 null Sarcoma_SARC_TCGA-FX-A76Y-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FASN Pathway Commons Protein-Protein Interactions 1.0 null PPARD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19772 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B8-01A-31R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE183041_1_v_0_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null SNX5 Pathway Commons Protein-Protein Interactions 1.0 null SNU410 DepMap CRISPR Gene Dependency 1.0 2.07346 ALG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97493 PMC7415402-oncotarget-11-2995-s004.xlsx-EWS-FLI1_Type_1_vs_Type_2-Gene_Symbol_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null ZFYVE26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.452 496100576_HIP_dementia_TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.86649 NCIH2023 CCLE Cell Line Gene CNV Profiles 1.0 1.59149 RPL10A Pathway Commons Protein-Protein Interactions 1.0 null TLX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76489 OKAJIMA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08387 TE5 DepMap CRISPR Gene Dependency 1.0 3.11734 rostral ventral respiratory cell group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.8998 Reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 PBX3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EMC7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77019 GSE195559_2_v_7_notch1_human RummaGEO Gene Perturbation Signatures 1.0 null ARF4 Pathway Commons Protein-Protein Interactions 1.0 null THP1 DepMap CRISPR Gene Dependency 1.0 2.93044 Cell type cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.281 Brain Lower Grade Glioma_LGG_TCGA-DU-6406-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Alfuzosin DeepCoverMOA Drug Mechanisms of Action 1.0 0.25 CBX3 Pathway Commons Protein-Protein Interactions 1.0 null YBX1 Pathway Commons Protein-Protein Interactions 1.0 null Lung adenocarcinoma_LUAD_TCGA-05-4433-01A-22R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OVCAR-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.03185 ARNT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66439 ADD1 Pathway Commons Protein-Protein Interactions 1.0 null OVMANA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.30045 HNRNPH1 Pathway Commons Protein-Protein Interactions 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A8YI-01A-21R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC11979751-table_s1_trajectoryderivation_elad055.xlsx-Cluster_DE_Genes_Summary-Cluster_2_AP2_Up_GTF3A Rummagene Transcription Factor Associations 2026 1.0 null PANC 08.13 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.875672 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7433-01A-11R-2132-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CBL0137 DeepCoverMOA Drug Mechanisms of Action 1.0 0.81 GSE160304,GSE163392_2_v_3_zswim8_human RummaGEO Gene Perturbation Signatures 1.0 null MGE-Lateral region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.937336 SLC38A9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.54366 NSDHL Pathway Commons Protein-Protein Interactions 1.0 null homeostatic process GO Biological Process Annotations 2015 1.0 null H1FX Pathway Commons Protein-Protein Interactions 1.0 null EHD1 Pathway Commons Protein-Protein Interactions 1.0 null Integral component of synaptic membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.822 H3F3A Pathway Commons Protein-Protein Interactions 1.0 null cuneate nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.21123 Brain Lower Grade Glioma_LGG_TCGA-DU-6405-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null WM-9 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.899 PFKP Pathway Commons Protein-Protein Interactions 1.0 null lateral reticular nucleus (principal part) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.55376 RPL15 Pathway Commons Protein-Protein Interactions 1.0 null VDAC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98893 HSPA13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32633 GSE77108_8_v_9_saha_human RummaGEO Drug Perturbation Signatures 1.0 null cell morphogenesis involved in neuron differentiation GO Biological Process Annotations 2025 1.0 null VZ in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.61386 FOXA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15058 AA92593 DeepCoverMOA Drug Mechanisms of Action 1.0 0.75 Lung adenocarcinoma_LUAD_TCGA-55-6712-01A-11R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Neurosecretory vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.713 outer CP in (rostral) midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.54616 DYNC1LI2 Pathway Commons Protein-Protein Interactions 1.0 null primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.58482 KYSE-70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.893558 Lung squamous cell carcinoma_LUSC_TCGA-60-2703-01A-11R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ADIPOR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78922 LRIF1 Pathway Commons Protein-Protein Interactions 1.0 null CLIC1 Pathway Commons Protein-Protein Interactions 1.0 null PIGS Pathway Commons Protein-Protein Interactions 1.0 null GSE198228,GSE198245_0_v_2_apoe_human RummaGEO Gene Perturbation Signatures -1.0 null 496100478_HIP_dementia_TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.46097 Gastrointestinal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.15 LNZTA3WT4 COSMIC Cell Line Gene Mutation Profiles 1.0 null XPO1 Pathway Commons Protein-Protein Interactions 1.0 null posteroventral (inferior) parietal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.824716 REC1 CCLE Cell Line Gene CNV Profiles -1.0 -1.51569 E2F1 JASPAR Predicted Transcription Factor Targets 1.0 null FOS JASPAR Predicted Transcription Factor Targets 1.0 null SQRDL Pathway Commons Protein-Protein Interactions 1.0 null JL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.05081 NuA4 histone acetyltransferase complex COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 testis_7b HPA Tissue Sample Gene Expression Profiles 1.0 1.70034 RPL6 Pathway Commons Protein-Protein Interactions 1.0 null GSE174701_5_v_6_maml3_human RummaGEO Gene Perturbation Signatures 1.0 null PMC12183081-41388_2025_3375_MOESM8_ESM.xlsx-Sheet1-Table_S7_List_of_differentially_alternative_splicing_genes_in_osteosarcoma_cell_lines_after_knocking_down_the_YBX1_gene_P_0_05_Related_to_Fig_6C_YBX1 Rummagene Transcription Factor Associations 2026 1.0 null NSD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65129 TMEM50A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14279 VZ in septal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.08364 ARF3 Pathway Commons Protein-Protein Interactions 1.0 null CERS4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93716 CEBPA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.4185 ATP1A1 Pathway Commons Protein-Protein Interactions 1.0 null posteroventral (inferior) parietal cortex_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.05861 Liver hepatocellular carcinoma_LIHC_TCGA-BC-4073-01B-02R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-A65E-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IDS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01472 NHERF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28469 TLN1 Pathway Commons Protein-Protein Interactions 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A6W2-06A-22R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null outer SZ in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.878298 extracellular vesicular exosome GO Cellular Component Annotations 2015 1.0 null TTC709 DepMap CRISPR Gene Dependency 1.0 4.18203 SW 480 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.829253 PMC7415402-oncotarget-11-2995-s004.xlsx-EWS-FLI1_Type_1_vs_Type_3-Gene_Symbol_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null NCIH2227 CCLE Cell Line Gene CNV Profiles 1.0 1.84228 PPIA Pathway Commons Protein-Protein Interactions 1.0 null RAB13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.92351 retina homeostasis GO Biological Process Annotations 2015 1.0 null GSE180793_1_v_0_sorl1_human RummaGEO Gene Perturbation Signatures -1.0 null cell part LOCATE Predicted Protein Localization Annotations 1.0 null GOLGA7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67032 GSE233647_2_v_0_docetaxel_human RummaGEO Drug Perturbation Signatures 1.0 null ACP1 Pathway Commons Protein-Protein Interactions 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-43-6773-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE154577_6_v_10_plagl1_human RummaGEO Gene Perturbation Signatures 1.0 null DPF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68674 ventrolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.29618 RPS2 Pathway Commons Protein-Protein Interactions 1.0 null outer SZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.09936 SP in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.33043 GSE160817_4_v_1_slamf6_human RummaGEO Gene Perturbation Signatures -1.0 null RPS9 Pathway Commons Protein-Protein Interactions 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1IB-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ADNP Pathway Commons Protein-Protein Interactions 1.0 null limitans nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.15994 H2AFJ Pathway Commons Protein-Protein Interactions 1.0 null SW684 COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Unnamed_13_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null NCOR-22424771-293T-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-8111-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EPB41L2 Pathway Commons Protein-Protein Interactions 1.0 null Lung adenocarcinoma_LUAD_TCGA-05-4398-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZBTB33_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null mediodorsal nucleus of thalamus_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.871804 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M9-01A-23R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE175787_4_v_7_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7438-01A-21R-2132-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC6080909-JEM_20171312_TableS1.xlsx-miR-196_predicted-Table_S1_miR-196a_b_predicted_targets_by_PITA_PicTar_TargetScan_and_DIANA_prediction_algorithms_ZFP1 Rummagene Transcription Factor Associations 2026 1.0 null GSE235550_2_v_0_hspa9_human RummaGEO Gene Perturbation Signatures -1.0 null PMC12069319-Table1.xlsx-OCAB_p35_BirA-Gene_Symbol_POU2AF1 Rummagene Transcription Factor Associations 2026 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-22-1011-01A-01R-0692-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CREM JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.3843 TORC2 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.276 RPL23A Pathway Commons Protein-Protein Interactions 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BK-01B-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DIAPH1 Pathway Commons Protein-Protein Interactions 1.0 null NCI-H2009 COSMIC Cell Line Gene Mutation Profiles 1.0 null CDC42EP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28326 BC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1IA-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SPB06189 DeepCoverMOA Drug Mechanisms of Action 1.0 0.54 KMS28BM CCLE Cell Line Gene CNV Profiles -1.0 -1.75602 GSE226249_2_v_1_pirfenidone_human RummaGEO Drug Perturbation Signatures -1.0 null intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null GSE139455_7_v_6_stat3_human RummaGEO Gene Perturbation Signatures 1.0 null Brain Lower Grade Glioma_LGG_TCGA-CS-5390-01A-02R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null oculomotor nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.8295 TK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23986 CEBPA-26348894-LIVER-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GN-06A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RNF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.81902 LZTS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83518 ARRDC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.01839 NUDT4 Pathway Commons Protein-Protein Interactions 1.0 null GSE154936_3_v_2_remdesivir_human RummaGEO Drug Perturbation Signatures 1.0 null NCI-H64 COSMIC Cell Line Gene Mutation Profiles 1.0 null HLA-A Pathway Commons Protein-Protein Interactions 1.0 null MKKS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25097 Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4TZ-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCL Pathway Commons Protein-Protein Interactions 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2942-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE216043_3_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null extracellular region part GO Cellular Component Annotations 2015 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4217-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null orbital frontal cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.835446 MCCC1 Pathway Commons Protein-Protein Interactions 1.0 null PARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40971 CDK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59776 CYFIP1 Pathway Commons Protein-Protein Interactions 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-P7-A5NY-05A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.889519 IDH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55992 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A556-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SLC16A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66662 GOT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25211 Neurodevelopmental disorder with cerebellar atrophy and motor dysfunction DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.919 GSE225901_0_v_1_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null COLO-668 COSMIC Cell Line Gene Mutation Profiles 1.0 null adult retina HPM Cell Type and Tissue Protein Expression Profiles -1.0 -1.17459 GSE102505_1_v_2_tunicamycin_human RummaGEO Drug Perturbation Signatures 1.0 null NCOA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5472 GSE168401_1_v_3_harmine_human RummaGEO Drug Perturbation Signatures 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-BI-A0VS-01A-11R-A10U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE258991_1_v_0_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null GSE169617_1_v_2_azacitidine_human RummaGEO Drug Perturbation Signatures -1.0 null MHH-ES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.43592 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7435-01A-11R-2132-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-BC-4072-01B-11R-A155-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null biological_process GO Biological Process Annotations 2015 1.0 null PLS1 Pathway Commons Protein-Protein Interactions 1.0 null Acetaminophen CTD Gene-Chemical Interactions 1.0 null CHMP4B Pathway Commons Protein-Protein Interactions 1.0 null CYTH1 Pathway Commons Protein-Protein Interactions 1.0 null RPL26L1 Pathway Commons Protein-Protein Interactions 1.0 null RPS3 Pathway Commons Protein-Protein Interactions 1.0 null NACA Pathway Commons Protein-Protein Interactions 1.0 null Dapagliflozin DeepCoverMOA Drug Mechanisms of Action -1.0 -0.25 Synapse COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 Lung squamous cell carcinoma_LUSC_TCGA-43-6143-01A-11R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-E1-5318-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TGBC1TKB COSMIC Cell Line Gene Mutation Profiles 1.0 null C1GALT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36855 Lung disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.066 lm2 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.854 polymeric cytoskeletal fiber GO Cellular Component Annotations 2025 1.0 null molecular_function GO Molecular Function Annotations 2015 1.0 null GSE139455_7_v_3_stat3_human RummaGEO Gene Perturbation Signatures 1.0 null KYSE-140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13502 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7414-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Breast disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.211 FOXN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.88783 RPL11 Pathway Commons Protein-Protein Interactions 1.0 null single-organism developmental process GO Biological Process Annotations 2015 1.0 null VRK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22328 Blood microparticle COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 SG in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.83923 Integument TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A50E-01A-21R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RPL36 Pathway Commons Protein-Protein Interactions 1.0 null KIF5B Pathway Commons Protein-Protein Interactions 1.0 null ESO26 DepMap CRISPR Gene Dependency 1.0 2.73047 HIST2H2BF Pathway Commons Protein-Protein Interactions 1.0 null ZNF461 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42581 VMRC-LCD Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.2048 TCF3 ENCODE Transcription Factor Targets 1.0 null ASPC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.962829 GSE96777,GSE96778_1_v_0_zbtb4_human RummaGEO Gene Perturbation Signatures 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-A46G-01A-31R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary motor cortex (area M1, area 4)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.04896 SSRP1 Pathway Commons Protein-Protein Interactions 1.0 null anterior amygdaloid area Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.30234 Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.517 SND1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65202 RAB11A Pathway Commons Protein-Protein Interactions 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-HR-A2OH-06A-11R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null XPO7 Pathway Commons Protein-Protein Interactions 1.0 null posteroventral (inferior) parietal cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.930159 PHB Pathway Commons Protein-Protein Interactions 1.0 null SOX11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4362 GSE180525,GSE180528_2_v_0_tbx3_human RummaGEO Gene Perturbation Signatures -1.0 null Sarcoma_SARC_TCGA-WK-A8XY-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH1793 CCLE Cell Line Gene CNV Profiles -1.0 -1.58273 PMC9010637-mmc6.xlsx-5D-Figure_5D_Gene_Expression_Zhou_et_al_Application_of_SP3-Rox_to_identify_redox_changes_during_T_cell_maturation_SP3 Rummagene Transcription Factor Associations 2026 1.0 null reticulotegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.23485 GSE120756_2_v_9_tet2_human RummaGEO Gene Perturbation Signatures -1.0 null Breast Carcinoma DisGeNET Gene-Disease Associations 1.0 null HIST1H2BN Pathway Commons Protein-Protein Interactions 1.0 null GSE213228_2_v_5_irak2_human RummaGEO Gene Perturbation Signatures -1.0 null TUFT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51092 RALB Pathway Commons Protein-Protein Interactions 1.0 null IGF2BP1 Pathway Commons Protein-Protein Interactions 1.0 null GSE221327_10_v_11_clpp_human RummaGEO Gene Perturbation Signatures 1.0 null HSP90AB1 Pathway Commons Protein-Protein Interactions 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DB-A75K-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CLTC Pathway Commons Protein-Protein Interactions 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6482-01A-11R-1873-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TFAP2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55016 placenta_6b HPA Tissue Sample Gene Expression Profiles 1.0 0.871776 Lung adenocarcinoma_LUAD_TCGA-78-7146-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Intrinsic component of presynaptic membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.055 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7045-01A-31R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KARPAS-45 COSMIC Cell Line Gene Mutation Profiles 1.0 null RPS18 Pathway Commons Protein-Protein Interactions 1.0 null TIGD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14338 GSE200839,GSE233826_3_v_0_tnrc18_human RummaGEO Gene Perturbation Signatures 1.0 null G3BP1 Pathway Commons Protein-Protein Interactions 1.0 null PMC12069319-Table1.xlsx-OCAB_WT_BirA-Gene_Symbol_POU2AF1 Rummagene Transcription Factor Associations 2026 1.0 null JHOC5 CCLE Cell Line Gene CNV Profiles 1.0 1.81114 CAL 54 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.962829 SP1 Pathway Commons Protein-Protein Interactions 1.0 null RPS4X Pathway Commons Protein-Protein Interactions 1.0 null GSE164874_5_v_1_prednisolone_human RummaGEO Drug Perturbation Signatures -1.0 null OVKATE COSMIC Cell Line Gene Mutation Profiles 1.0 null RHEB Pathway Commons Protein-Protein Interactions 1.0 null Tizanidine DeepCoverMOA Drug Mechanisms of Action 1.0 0.27 FDFT1 Pathway Commons Protein-Protein Interactions 1.0 null Malignant Neoplasm DisGeNET Gene-Disease Associations 1.0 null NCI-H2106 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.47396 SW 948 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.48347 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4355-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null L540 CCLE Cell Line Gene CNV Profiles 1.0 1.3357 RPS26 Pathway Commons Protein-Protein Interactions 1.0 null 9-Aminocamptothecin DeepCoverMOA Drug Mechanisms of Action 1.0 1.25 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-A4D4-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAPK1 Pathway Commons Protein-Protein Interactions 1.0 null Colorectal Carcinoma DisGeNET Gene-Disease Associations 1.0 null RPS12 Pathway Commons Protein-Protein Interactions 1.0 null SCCPDH Pathway Commons Protein-Protein Interactions 1.0 null MZ in posteror frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.22905 Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6YC-01A-12R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1806 CCLE Cell Line Gene CNV Profiles 1.0 2.17335 IFT27 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98595 C2CD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.10494 lateral subdivision of BNST Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.37163 DHX9 Pathway Commons Protein-Protein Interactions 1.0 null DDX21 Pathway Commons Protein-Protein Interactions 1.0 null GSE235701,GSE261434_0_v_1_enasidenib_human RummaGEO Drug Perturbation Signatures 1.0 null UCK2 Pathway Commons Protein-Protein Interactions 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.20953 extracellular vesicle GO Cellular Component Annotations 2015 1.0 null C3A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.13804 hsa-miR-3613-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 KMS-28PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.61046 OSC-19 COSMIC Cell Line Gene Mutation Profiles 1.0 null HSDL2 Pathway Commons Protein-Protein Interactions 1.0 null posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 3.06838 GSE193258,GSE193259_2_v_4_osimertinib_human RummaGEO Drug Perturbation Signatures 1.0 null inner CP in midcingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.877498 MXD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40061 agranular insular cortex (area Iag) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.06149 GSE216043_10_v_9_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null SNU-182 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.984438 NCIH1573 DepMap CRISPR Gene Dependency 1.0 6.39785 GSE258991_5_v_2_enzalutamide_human RummaGEO Drug Perturbation Signatures -1.0 null ZBTB33 ENCODE Transcription Factor Targets 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-8113-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100392_HIP_dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.02217 ARF6 Pathway Commons Protein-Protein Interactions 1.0 null ZNF354C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.8125 dorsal motor nucleus of the vagus (vagal nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.29124 testis_7f HPA Tissue Sample Gene Expression Profiles 1.0 1.4242 Organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.485 GSE102505_5_v_0_tunicamycin_human RummaGEO Drug Perturbation Signatures -1.0 null FMR1 Pathway Commons Protein-Protein Interactions 1.0 null EPCAM Pathway Commons Protein-Protein Interactions 1.0 null DUSP23 Pathway Commons Protein-Protein Interactions 1.0 null HNRNPH2 Pathway Commons Protein-Protein Interactions 1.0 null SKP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44159 LXFL529 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.71867 FNTA Pathway Commons Protein-Protein Interactions 1.0 null Mardepodect DeepCoverMOA Drug Mechanisms of Action -1.0 -0.31 Cortical Lewy body COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.687 RPS5 Pathway Commons Protein-Protein Interactions 1.0 null NCIH1915 CCLE Cell Line Gene CNV Profiles 1.0 2.12272 Epithelium TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Prostate adenocarcinoma_PRAD_TCGA-HC-7748-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Thoracic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.21 outer SZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.987607 ventrolateral prefrontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.14948 SARS-BatSRBD_60Hour_23935999_GSE47961 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.99812 KMS-28BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.58761 RAC2 Pathway Commons Protein-Protein Interactions 1.0 null HUH-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.962829 DYNC2H1 Pathway Commons Protein-Protein Interactions 1.0 null PHGDH Pathway Commons Protein-Protein Interactions 1.0 null A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB2-627E_24Hour_None_GSE43203 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.68978 GSE165334_3_v_1_dabrafenib_human RummaGEO Drug Perturbation Signatures 1.0 null Respiratory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.027 caudal portion of VFC (area 44) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00536 JVE127 DepMap CRISPR Gene Dependency 1.0 3.90295 Brain Lower Grade Glioma_LGG_TCGA-CS-4942-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7963-01B-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MKN74 CCLE Cell Line Gene CNV Profiles 1.0 1.42229 HIST1H2BH Pathway Commons Protein-Protein Interactions 1.0 null A-Netherlands-602-2009(H1N1)_7Hour_None_GSE40844 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.55891 MKN-74 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.48809 pedunculo(pontine) tegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.892466 AIP Pathway Commons Protein-Protein Interactions 1.0 null PACS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40676 Liver hepatocellular carcinoma_LIHC_TCGA-BC-A216-01A-11R-A155-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-95-7039-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GATA4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.0983 ELOA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.96876 NAA15 Pathway Commons Protein-Protein Interactions 1.0 null AP3S1 Pathway Commons Protein-Protein Interactions 1.0 null Endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 ZNF697 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12685 VSNL1 Pathway Commons Protein-Protein Interactions 1.0 null cerebellar cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.26034 COR-L88 COSMIC Cell Line Gene Mutation Profiles 1.0 null RPL14 Pathway Commons Protein-Protein Interactions 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-7752-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TPD52 Pathway Commons Protein-Protein Interactions 1.0 null COX11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29694 parasubicular cortex (parasubiculum) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.973769 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5890-11A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZBTB14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59567 MFE-319 COSMIC Cell Line Gene Mutation Profiles 1.0 null MYO18A Pathway Commons Protein-Protein Interactions 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7415-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BZW2 Pathway Commons Protein-Protein Interactions 1.0 null UACC-257 COSMIC Cell Line Gene Mutation Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-BC-A8YO-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ADAP1 Pathway Commons Protein-Protein Interactions 1.0 null REPS1 Pathway Commons Protein-Protein Interactions 1.0 null PMC10245467-mmc3.pdf-259-ZNF701_ZNF701 Rummagene Transcription Factor Associations 2026 1.0 null SPECC1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73963 ACSL3 Pathway Commons Protein-Protein Interactions 1.0 null TINAGL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92033 ENTPD7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.72628 RABL6 Pathway Commons Protein-Protein Interactions 1.0 null UHRF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28941 RPL18 Pathway Commons Protein-Protein Interactions 1.0 null Montelukast DeepCoverMOA Drug Mechanisms of Action 1.0 0.51 H4/H2A histone acetyltransferase complex COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 RHOF GTPase cycle Reactome Pathways 2024 1.0 null Oviduct epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.745 DDX6 Pathway Commons Protein-Protein Interactions 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-8097-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lower limb region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.97898 MDA-MB-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.837042 SLC25A24 Pathway Commons Protein-Protein Interactions 1.0 null GSE213228_4_v_0_irak2_human RummaGEO Gene Perturbation Signatures -1.0 null PMC12069319-Table1.xlsx-OCAB_p34_BirA-Gene_Symbol_POU2AF1 Rummagene Transcription Factor Associations 2026 1.0 null AP1B1 Pathway Commons Protein-Protein Interactions 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6488-01A-12R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100470_HIP_possible Alzheimer's disease_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 5.73666 extracellular organelle GO Cellular Component Annotations 2015 1.0 null Histone acetyltransferase complex COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8315-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null icSARS CoV_0Hour_None_GSE37827 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -3.04509 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2J7-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF768 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.1055 SUMO1 Pathway Commons Protein-Protein Interactions 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8636-01A-21R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SG in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.924878 RPN1 Pathway Commons Protein-Protein Interactions 1.0 null ACTR3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75243 vesicle GO Cellular Component Annotations 2015 1.0 null FAR2 Pathway Commons Protein-Protein Interactions 1.0 null striatum_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.04254 PMC8190596-mmc2.xlsx-RUNX1_mut-RUNX1_mut_RUNX1 Rummagene Transcription Factor Associations 2026 1.0 null ZNF8 Pathway Commons Protein-Protein Interactions 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.15505 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7423-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.4923 SERPING1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20142 MARCKSL1 Pathway Commons Protein-Protein Interactions 1.0 null inner SZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.13119 Rectum adenocarcinoma_READ_TCGA-EF-5831-01A-01R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Ankyrin repeat InterPro Predicted Protein Domain Annotations 1.0 null H2731 COSMIC Cell Line Gene Mutation Profiles 1.0 null BT-20 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.875672 transient Purkinje cell clusters Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.37679 CTCF ENCODE Transcription Factor Targets 1.0 null LP1 CCLE Cell Line Gene CNV Profiles -1.0 -1.50104 JHOM1 CCLE Cell Line Gene CNV Profiles -1.0 -1.39478 Skin Cutaneous Melanoma_SKCM_TCGA-IH-A3EA-01A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null spinal trigeminal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.13502 MOLP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14873 EN COSMIC Cell Line Gene Mutation Profiles 1.0 null NCI-H810 COSMIC Cell Line Gene Mutation Profiles 1.0 null Abiraterone1 DeepCoverMOA Drug Mechanisms of Action -1.0 -0.4 external granular (germinal) layer of upper rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.861448 GSE223893_11_v_10_setd2_human RummaGEO Gene Perturbation Signatures 1.0 null NCI-H2452 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.900023 TPBGL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26607 RPS20 Pathway Commons Protein-Protein Interactions 1.0 null HEP G2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.34991 GSE216043_11_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.95677 TWIST1_01_254 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.59948 CTBP1 Pathway Commons Protein-Protein Interactions 1.0 null basal nucleus of Meynert Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.882888 SEPT2 Pathway Commons Protein-Protein Interactions 1.0 null GSE216043_7_v_4_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null striatum_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.838141 H3F3C Pathway Commons Protein-Protein Interactions 1.0 null Lung adenocarcinoma_LUAD_TCGA-73-4670-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null WM1799 DepMap CRISPR Gene Dependency 1.0 3.52103 HEC1A CCLE Cell Line Gene CNV Profiles 1.0 1.33257 H4 histone acetyltransferase complex COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 OCIMY5 CCLE Cell Line Gene CNV Profiles -1.0 -1.67514 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BL-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null iNOS-S100A8/A9 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.022 LDHA Pathway Commons Protein-Protein Interactions 1.0 null Internal male genital organ TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 STAU1 Pathway Commons Protein-Protein Interactions 1.0 null Rectum adenocarcinoma_READ_TCGA-DC-6157-01A-11R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7416-11A-01R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PRKCG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73376 Colorectal cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.021 KYSE-180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.837042 NCI-H1915 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.56613 hsa-miR-412 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 ventrolateral prefrontal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.71453 RPL28 Pathway Commons Protein-Protein Interactions 1.0 null parataenial nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.15982 CTBP2 Pathway Commons Protein-Protein Interactions 1.0 null IQGAP1 Pathway Commons Protein-Protein Interactions 1.0 null Actin, conserved site InterPro Predicted Protein Domain Annotations 1.0 null M140325 DepMap CRISPR Gene Dependency 1.0 2.48982 PKM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85478 ERAP1 Pathway Commons Protein-Protein Interactions 1.0 null RRAS Pathway Commons Protein-Protein Interactions 1.0 null EEF1A1 Pathway Commons Protein-Protein Interactions 1.0 null NCI-H1793 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.44531 Perturb_107_KD_STON2_SRP135729 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.66007 hsa-miR-4664-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 KYSE-520 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.893558 HIST3H2BB Pathway Commons Protein-Protein Interactions 1.0 null TNNI3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.1451 PTGES2 Pathway Commons Protein-Protein Interactions 1.0 null ZNF324B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38162 HSD17B4 Pathway Commons Protein-Protein Interactions 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8519-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.07006 NCO2 DepMap CRISPR Gene Dependency 1.0 3.62642 multiform (lateral) division of MD Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.11723 CKMT1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88018 TUBA1A Pathway Commons Protein-Protein Interactions 1.0 null Inguinal canal TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.58 COLO680N CCLE Cell Line Gene CNV Profiles 1.0 1.6167 AP2B1 Pathway Commons Protein-Protein Interactions 1.0 null actin filament GO Cellular Component Annotations 2025 1.0 null ACTA2 Pathway Commons Protein-Protein Interactions 1.0 null SNAPIN Pathway Commons Protein-Protein Interactions 1.0 null TAGLN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64263 MYH9 Pathway Commons Protein-Protein Interactions 1.0 null SK-MEL-28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.91222 NCIH2106 CCLE Cell Line Gene CNV Profiles -1.0 -1.48399 family GeneRIF Biological Term Annotations 1.0 null PRDM7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17615 GSE195559_6_v_1_notch1_human RummaGEO Gene Perturbation Signatures -1.0 null GSE174701_5_v_8_maml3_human RummaGEO Gene Perturbation Signatures 1.0 null SKMEL2 CCLE Cell Line Gene CNV Profiles -1.0 -1.95801 TMOD3 Pathway Commons Protein-Protein Interactions 1.0 null HIST1H2BM Pathway Commons Protein-Protein Interactions 1.0 null NUGC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.962829 GSE202434,GSE202438_8_v_1_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2998-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POTEF Pathway Commons Protein-Protein Interactions 1.0 null HIST1H4F Pathway Commons Protein-Protein Interactions 1.0 null RPN2 Pathway Commons Protein-Protein Interactions 1.0 null NAMALWA COSMIC Cell Line Gene Mutation Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7438-11A-01R-2132-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DH-5141-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Supramolecular polymer COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 PPP1CA Pathway Commons Protein-Protein Interactions 1.0 null LUDLU1 DepMap CRISPR Gene Dependency 1.0 2.55053 YD15 DepMap CRISPR Gene Dependency 1.0 2.59471 amygdaloid complex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.0197 GSE147876,GSE147877_2_v_10_enzalutamide_human RummaGEO Drug Perturbation Signatures -1.0 null ZFR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07081 MRPL40 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.19884 GSE201309_5_v_3_matrine_human RummaGEO Drug Perturbation Signatures 1.0 null Endocrine system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.335 PMC11297914-41389_2024_531_MOESM1_ESM.pdf-283-ZNF488_ZNF488 Rummagene Transcription Factor Associations 2026 1.0 null OVISE DepMap CRISPR Gene Dependency 1.0 4.62588 membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-CS-4941-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null nucleus LOCATE Predicted Protein Localization Annotations 1.0 null G-402 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.86794 Lung adenocarcinoma_LUAD_TCGA-55-6982-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF16 Pathway Commons Protein-Protein Interactions 1.0 null 496100539_HIP_probable Alzheimer's disease_TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.08066 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7255-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-86-8055-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RPS24 Pathway Commons Protein-Protein Interactions 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-8114-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null orbital frontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.03968 organelle LOCATE Predicted Protein Localization Annotations 1.0 null SRP54 Pathway Commons Protein-Protein Interactions 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4766-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GIGYF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41535 GAPDH Pathway Commons Protein-Protein Interactions 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-IB-8127-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EL-01A-11R-A155-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Actin/actin-like conserved site InterPro Predicted Protein Domain Annotations 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-CC-5261-01A-01R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GNG4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20211 AMO1 DepMap CRISPR Gene Dependency 1.0 6.18616 HIST1H2BD Pathway Commons Protein-Protein Interactions 1.0 null A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc_12Hour_None_GSE43204 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.70994 SK-MEL-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.98712 Ruffle membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.032 ATP5A1 Pathway Commons Protein-Protein Interactions 1.0 null lateral hypothalamic area, tuberal part Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.02714 extracellular space GO Cellular Component Annotations 2015 1.0 null P68-20966046-HELA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null G402 CCLE Cell Line Gene CNV Profiles 1.0 1.58751 POLR2A ENCODE Transcription Factor Targets 1.0 null MGAT5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65239 GSE226408_1_v_0_inpp4b_human RummaGEO Gene Perturbation Signatures -1.0 null PMC12238561-42003_2025_8460_MOESM2_ESM.xlsx-IDs_S23_LF_C1_24h-Unnamed_5_LTF Rummagene Transcription Factor Associations 2026 1.0 null Ovarian cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.363 RPL35 Pathway Commons Protein-Protein Interactions 1.0 null MDA-MB-436 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.43914 IZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.27517 Brain Lower Grade Glioma_LGG_TCGA-HT-8110-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NOTO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27484 JURKAT COSMIC Cell Line Gene Mutation Profiles 1.0 null Supramolecular fiber COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 IRF2BPL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09493 retroparafascicular area of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.833603 TFRC Pathway Commons Protein-Protein Interactions 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2826-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZBTB7C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.3393 ME-180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.837042 RMND5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71812 RC3H1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55322 amygdaloid complex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.82487 dorsolateral prefrontal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.44858 AHNAK Pathway Commons Protein-Protein Interactions 1.0 null GSE116492,GSE116495_3_v_1_stag2_human RummaGEO Gene Perturbation Signatures 1.0 null ZNF121 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55748 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GX-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CLK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69113 hippocampus (hippocampal formation)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.10593 RPL36A Pathway Commons Protein-Protein Interactions 1.0 null LGALS4 Pathway Commons Protein-Protein Interactions 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-5505-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RPL13AP3 Pathway Commons Protein-Protein Interactions 1.0 null BL70 CCLE Cell Line Gene CNV Profiles -1.0 -1.69806 KPNA4 Pathway Commons Protein-Protein Interactions 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-PR-A5PG-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posteroventral (inferior) parietal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.31671 S100A16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.94671 PMC3516044__F3 PFOCR Pathway Figure Associations 2023 1.0 null alitretinoin_homo sapiens_gpl6480_gse43090 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Thoracic cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.214 CDK5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96296 PLD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80943 IZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.902658 PHLDB1 Pathway Commons Protein-Protein Interactions 1.0 null TCF3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null P12-ICHIKAWA COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE175787_4_v_0_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null medioventral part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.07907 GSE213228_4_v_5_irak2_human RummaGEO Gene Perturbation Signatures -1.0 null BT-549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.38709 Acute Myeloid Leukemia_LAML_TCGA-AB-2842-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE191015_0_v_3_gsdmb_human RummaGEO Gene Perturbation Signatures -1.0 null CTCF_HGPS cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OVMANA CCLE Cell Line Gene CNV Profiles 1.0 1.74989 FAM168B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7005 Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3RD-01A-12R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-86-8074-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 G130 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.950178 HK-1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.806 MHHES1 CCLE Cell Line Gene CNV Profiles 1.0 1.32827 Lung adenocarcinoma_LUAD_TCGA-55-8208-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SB 225002 DeepCoverMOA Drug Mechanisms of Action 1.0 0.88 organelle GO Cellular Component Annotations 2015 1.0 null A-498 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.900023 RPL5 Pathway Commons Protein-Protein Interactions 1.0 null Lung adenocarcinoma_LUAD_TCGA-05-5429-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Ovarian disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.387 SEC24D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.74631 POGZ Pathway Commons Protein-Protein Interactions 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5JI-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VZ in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.20958 Kidney Chromophobe_KICH_TCGA-KO-8405-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Rectum adenocarcinoma_READ_TCGA-DC-5337-01A-01R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TT CCLE Cell Line Gene CNV Profiles 1.0 2.51692 HADHB Pathway Commons Protein-Protein Interactions 1.0 null ventrolateral prefrontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.904576 GSE102505_5_v_3_tunicamycin_human RummaGEO Drug Perturbation Signatures -1.0 null gigantocellular reticular nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.32484 SPTBN1 Pathway Commons Protein-Protein Interactions 1.0 null HBL-100 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.31717 SW948 CCLE Cell Line Gene CNV Profiles 1.0 1.45285 Brain Lower Grade Glioma_LGG_TCGA-CS-4944-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H513 COSMIC Cell Line Gene Mutation Profiles 1.0 null OSBPL11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65349 SRSF4 Pathway Commons Protein-Protein Interactions 1.0 null HMC18 CCLE Cell Line Gene CNV Profiles 1.0 1.9913 G140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.875672 FOXH1-21741376-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null POTEI Pathway Commons Protein-Protein Interactions 1.0 null SLC25A3 Pathway Commons Protein-Protein Interactions 1.0 null AKT1 Pathway Commons Protein-Protein Interactions 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5891-11A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE193258,GSE193259_9_v_13_osimertinib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE213228_2_v_0_irak2_human RummaGEO Gene Perturbation Signatures -1.0 null 496100584_HIP_probable Alzheimer's disease_no TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.37464 VZ in thalamic region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.4168 Sarcoma_SARC_TCGA-DX-A3U8-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF226 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35431 CHAMP1 Pathway Commons Protein-Protein Interactions 1.0 null Lung adenocarcinoma_LUAD_TCGA-91-6848-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HIST1H2AI Pathway Commons Protein-Protein Interactions 1.0 null kinase binding GO Molecular Function Annotations 2023 1.0 null PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC Rummagene Transcription Factor Associations 2026 1.0 null Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Reactome Pathways 2024 1.0 null blood microparticle GO Cellular Component Annotations 2015 1.0 null NUGC-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14023 BAIAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18498 KPNB1 Pathway Commons Protein-Protein Interactions 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3BM-11A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU-C5 COSMIC Cell Line Gene Mutation Profiles 1.0 null RPL36AL Pathway Commons Protein-Protein Interactions 1.0 null TUBA1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.92201 primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.07246 posteroventral (inferior) parietal cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.34825 HIST3H3 Pathway Commons Protein-Protein Interactions 1.0 null developmental process GO Biological Process Annotations 2015 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-BF-A5ES-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NuA4 histone acetyltransferase complex GO Cellular Component Annotations 2025 1.0 null RPS19 Pathway Commons Protein-Protein Interactions 1.0 null RPL34 Pathway Commons Protein-Protein Interactions 1.0 null HIST1H2BJ Pathway Commons Protein-Protein Interactions 1.0 null UCP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10632 HT CCLE Cell Line Gene CNV Profiles -1.0 -2.30576 ARF5 Pathway Commons Protein-Protein Interactions 1.0 null DNMT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12201 COLO 857 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.27538 Disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.552 Granulosa cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.86 ZNF44 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79497 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 IZ in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.42479 RUNX2 JASPAR Predicted Transcription Factor Targets 1.0 null EZH2 Pathway Commons Protein-Protein Interactions 1.0 null primary auditory cortex (core)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.96468 Adrenocortical carcinoma_ACC_TCGA-P6-A5OG-01A-22R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lineagespecific GeneRIF Biological Term Annotations 1.0 null PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_3_in_RNA-seq_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null membrane LOCATE Curated Protein Localization Annotations 1.0 null RPL35A Pathway Commons Protein-Protein Interactions 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GL-06A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC10679662-mmc3.xlsx-NC-D5-ZEB2-Mutant-Upregulated-Gene_Symbol_ZEB2 Rummagene Transcription Factor Associations 2026 1.0 null RBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.11139 GSE131649_6_v_8_hemin_human RummaGEO Drug Perturbation Signatures -1.0 null biological regulation GO Biological Process Annotations 2015 1.0 null DPPA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67047 GRPEL1 Pathway Commons Protein-Protein Interactions 1.0 null medial subdivision of area 10 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.05352 HIST1H2BO Pathway Commons Protein-Protein Interactions 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A0VL-01A-21R-A10U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null caudal division of IPC (area 39) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.903482 MYBBP1A Pathway Commons Protein-Protein Interactions 1.0 null GSE185744,GSE185747_2_v_3_sox9_human RummaGEO Gene Perturbation Signatures -1.0 null hsa-miR-3662 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 TMEM221 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31419 GSE131649_6_v_0_hemin_human RummaGEO Drug Perturbation Signatures -1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-BF-A5ER-01A-12R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null proapoptotic GeneRIF Biological Term Annotations 1.0 null Lung adenocarcinoma_LUAD_TCGA-95-8039-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COV644 DepMap CRISPR Gene Dependency 1.0 2.50849 axonogenesis GO Biological Process Annotations 2025 1.0 null MAFG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.74579 RSV_48Hour_22398282_GSE32138 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.22844 Kidney Chromophobe_KICH_TCGA-KN-8431-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GATAD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97155 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A57G-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4354-01A-02R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-WW-A8ZI-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null WA-09 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.857 Adrenocortical carcinoma_ACC_TCGA-OR-A5JR-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TMEM33 Pathway Commons Protein-Protein Interactions 1.0 null CXCL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76537 Lung adenocarcinoma_LUAD_TCGA-97-7554-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Tapasin-ERp57 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.003 RPS11 Pathway Commons Protein-Protein Interactions 1.0 null TRMT10A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72682 CHMP2A Pathway Commons Protein-Protein Interactions 1.0 null SRPK1 Pathway Commons Protein-Protein Interactions 1.0 null H4/H2A histone acetyltransferase complex GO Cellular Component Annotations 2023 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A42Q-01A-11R-A23W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null axon development GO Biological Process Annotations 2025 1.0 null UBE2Z CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8093 SRSF5 Pathway Commons Protein-Protein Interactions 1.0 null GSE184087_2_v_1_tert_human RummaGEO Gene Perturbation Signatures 1.0 null internal segment of globus pallidus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.49118 Brain Lower Grade Glioma_LGG_TCGA-DB-5280-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null precommissural nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.03442 mediodorsal nucleus of thalamus_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.71453 ESYT1 Pathway Commons Protein-Protein Interactions 1.0 null POU2F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5192 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XP-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZFP36 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.72907 TUBA1C Pathway Commons Protein-Protein Interactions 1.0 null Lung adenocarcinoma_LUAD_TCGA-44-2665-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7ME-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXP1_01_234 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 1.32391 DMS 79 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.900023 AGPS Pathway Commons Protein-Protein Interactions 1.0 null DSTN Pathway Commons Protein-Protein Interactions 1.0 null H2591 COSMIC Cell Line Gene Mutation Profiles 1.0 null HIST1H3B Pathway Commons Protein-Protein Interactions 1.0 null Male reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 HMGA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22656 ECI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69768 PDS5A Pathway Commons Protein-Protein Interactions 1.0 null pote GeneRIF Biological Term Annotations 1.0 null NCI-H524 COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-49-6761-01A-31R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PKN2 Pathway Commons Protein-Protein Interactions 1.0 null Thymidine DeepCoverMOA Drug Mechanisms of Action 1.0 0.35 testis_7d HPA Tissue Sample Gene Expression Profiles 1.0 1.29838 HLA-H Pathway Commons Protein-Protein Interactions 1.0 null primary auditory cortex (core)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.97546 Lung squamous cell carcinoma_LUSC_TCGA-NK-A5D1-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.7611 Brain Lower Grade Glioma_LGG_TCGA-DH-A66D-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TATDN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.065 POLR2A_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null A-Netherlands-602-2009(H1N1)_36Hour_None_GSE40844 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.7709 DMS 53 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.67182 TPM3 Pathway Commons Protein-Protein Interactions 1.0 null ZNF670 Pathway Commons Protein-Protein Interactions 1.0 null RELB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.4635 POLR2A_A549_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5902 RPL12 Pathway Commons Protein-Protein Interactions 1.0 null GSE143662_3_v_1_dcp2_human RummaGEO Gene Perturbation Signatures -1.0 null PBX3 ENCODE Transcription Factor Targets 1.0 null CAPZB Pathway Commons Protein-Protein Interactions 1.0 null HIST1H2AD Pathway Commons Protein-Protein Interactions 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A706-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mediodorsal nucleus of thalamus_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.874556 SAS COSMIC Cell Line Gene Mutation Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B6-01A-21R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null G6PD Pathway Commons Protein-Protein Interactions 1.0 null DOTC24510 DepMap CRISPR Gene Dependency 1.0 3.53259 inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.30502 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IN-01A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.873215 RPL17 Pathway Commons Protein-Protein Interactions 1.0 null ACTG2 Pathway Commons Protein-Protein Interactions 1.0 null ACOT4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32172 SRSF6 Pathway Commons Protein-Protein Interactions 1.0 null CREB1 JASPAR Predicted Transcription Factor Targets 1.0 null GSE216043_7_v_0_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null cSARS Bat SRBD_24Hour_None_GSE37827 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.65864 Lung squamous cell carcinoma_LUSC_TCGA-63-7021-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LRRC59 Pathway Commons Protein-Protein Interactions 1.0 null SB-269970 DeepCoverMOA Drug Mechanisms of Action 1.0 0.35 lm7 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.209 PRKACA Pathway Commons Protein-Protein Interactions 1.0 null CTNND1 Pathway Commons Protein-Protein Interactions 1.0 null TOP3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6302 RPS10 Pathway Commons Protein-Protein Interactions 1.0 null TMOD2 Pathway Commons Protein-Protein Interactions 1.0 null KATOIII CCLE Cell Line Gene CNV Profiles -1.0 -1.51616 MESP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13206 CHRNA10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12798 primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.849612 POLR2AphosphoS2_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SMAD2/3-21741376-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null EVSA-T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05697 Breast cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.215 SRP72 Pathway Commons Protein-Protein Interactions 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6959-11A-01R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE154577_13_v_10_plagl1_human RummaGEO Gene Perturbation Signatures 1.0 null h16l104r5 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.063 cSARS Bat SRBD_12Hour_None_GSE37827 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.47836 RPL32 Pathway Commons Protein-Protein Interactions 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2823-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF660 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34856 PMC11938024-ADMA-37-2413413-s001.xlsx-Table_S1a_DE_Genes_analysis-Table_S1a_Differentailly_expressed_genes_Control_vs_NPs_treated_THP1_GLI2 Rummagene Transcription Factor Associations 2026 1.0 null HDHD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73941 substantia nigra development GO Biological Process Annotations 2025 1.0 null Intrinsic component of postsynaptic membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.934 RTN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35405 TTC549 DepMap CRISPR Gene Dependency 1.0 6.89674 COLO 680N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.14263 protein kinase binding GO Molecular Function Annotations 2025 1.0 null prostate_a HPA Tissue Sample Gene Expression Profiles 1.0 0.834752 Reproductive organ cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.337 breast GTEx Tissue Gene Expression Profiles 1.0 1.08665 primary motor cortex (area M1, area 4)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.01229 POLR2AphosphoS5_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SUM149PT DepMap CRISPR Gene Dependency 1.0 6.45816 cellular_component LOCATE Curated Protein Localization Annotations 1.0 null GSE221101_1_v_0_hopx_human RummaGEO Gene Perturbation Signatures -1.0 null GALR3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00574 salivary gland GTEx Tissue Gene Expression Profiles -1.0 -2.10021 ADD3 Pathway Commons Protein-Protein Interactions 1.0 null PMC3516044__F3 PFOCR Pathway Figure Associations 2024 1.0 null PHB2 Pathway Commons Protein-Protein Interactions 1.0 null Fluoxymesterone DeepCoverMOA Drug Mechanisms of Action 1.0 0.31 PMC12069319-Table1.xlsx-OCAB_WT_BirA-Gene_POU2AF1 Rummagene Transcription Factor Associations 2026 1.0 null GSE216043_7_v_9_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null Lung adenocarcinoma_LUAD_TCGA-55-7227-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NRF1 JASPAR Predicted Transcription Factor Targets 1.0 null HIST2H3A Pathway Commons Protein-Protein Interactions 1.0 null Sarcoma_SARC_TCGA-DX-A3U7-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null WDR75 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22282 GATA2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 H4/H2A histone acetyltransferase complex GO Cellular Component Annotations 2025 1.0 null TSPAN8 Pathway Commons Protein-Protein Interactions 1.0 null NOL11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 5.9248 inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.824482 Perturb_2815_KD_LSD1_SRP310243 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Golgi apparatus COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 1.495 GSE226770_1_v_0_atrx_human RummaGEO Gene Perturbation Signatures -1.0 null POLR2AphosphoS5_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null amygdaloid complex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.13755 STARD10 Pathway Commons Protein-Protein Interactions 1.0 null KIF3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4704 Prostate adenocarcinoma_PRAD_TCGA-CH-5751-01A-11R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3OO-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DMS53 CCLE Cell Line Gene CNV Profiles -1.0 -2.59849 GSE216988,GSE216989_0_v_1_decitabine_human RummaGEO Drug Perturbation Signatures 1.0 null ZNF84 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46727 ITPRID2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15805 Lung adenocarcinoma_LUAD_TCGA-50-5931-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5JT-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null WDR45B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61248 SLC25A5 Pathway Commons Protein-Protein Interactions 1.0 null DYNC1I2 Pathway Commons Protein-Protein Interactions 1.0 null LRPPRC Pathway Commons Protein-Protein Interactions 1.0 null PMC12069319-Table1.xlsx-OCAB_p34_BirA-Gene_POU2AF1 Rummagene Transcription Factor Associations 2026 1.0 null CD9 Pathway Commons Protein-Protein Interactions 1.0 null posteroventral (inferior) parietal cortex_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.24844 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7437-01A-21R-2132-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mediodorsal nucleus of thalamus_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.3396 PAN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60924 CACNG7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01472 cytoskeleton GO Cellular Component Annotations 2025 1.0 null intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null orbital frontal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.89542 HIST1H2AC Pathway Commons Protein-Protein Interactions 1.0 null AR ChEA Transcription Factor Targets 1.0 null SPTAN1 Pathway Commons Protein-Protein Interactions 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FV-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H4-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BJ-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Rectum adenocarcinoma_READ_TCGA-EF-5830-01A-01R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-7123-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsolateral prefrontal cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.835004 2-Bromophenethylamine DeepCoverMOA Drug Mechanisms of Action 1.0 0.38 NCI-H650 COSMIC Cell Line Gene Mutation Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DB-5273-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HIST2H2BE Pathway Commons Protein-Protein Interactions 1.0 null PMC12271601-mmc2.xlsx-OUT_cells_01-Gene_Symbol_TCF23 Rummagene Transcription Factor Associations 2026 1.0 null ZNF283 Pathway Commons Protein-Protein Interactions 1.0 null GSE160304,GSE163392_7_v_3_zswim8_human RummaGEO Gene Perturbation Signatures 1.0 null Female reproductive organ cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.296 Lung adenocarcinoma_LUAD_TCGA-44-6147-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-3646 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 NIPSNAP1 Pathway Commons Protein-Protein Interactions 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7423-11A-01R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null STXBP5 Pathway Commons Protein-Protein Interactions 1.0 null MYC_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.21764 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A4XK-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LBR Pathway Commons Protein-Protein Interactions 1.0 null ZNF460 Pathway Commons Protein-Protein Interactions 1.0 null ITGA6 Pathway Commons Protein-Protein Interactions 1.0 null JM1 DepMap CRISPR Gene Dependency 1.0 3.51827 H3-3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95405 SNU-449 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.962829 HNRNPA1 Pathway Commons Protein-Protein Interactions 1.0 null SCP2 Pathway Commons Protein-Protein Interactions 1.0 null SNU119 CCLE Cell Line Gene CNV Profiles 1.0 1.77441 differentiation GeneRIF Biological Term Annotations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-S9-A7R7-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SPI1-23127762-K562-HUMAN ChEA Transcription Factor Targets 2022 1.0 null 496100383_HIP_no dementia_no TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.67032 Acute Myeloid Leukemia_LAML_TCGA-AB-2813-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null 496100519_HIP_probable Alzheimer's disease_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 6.44569 dorsal thalamus_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.926228 reuniens nucleus (medioventral nucleus) of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.44079 GSE202434,GSE202438_6_v_1_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null Rectum adenocarcinoma_READ_TCGA-DC-6160-01A-11R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null E2F7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 54.0161 primary auditory cortex (core)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.922327 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7411-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH69 CCLE Cell Line Gene CNV Profiles -1.0 -1.39055 inner CP in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.845453 NCIH1299 CCLE Cell Line Gene CNV Profiles 1.0 1.54844 KRAS Pathway Commons Protein-Protein Interactions 1.0 null actin cytoskeleton GO Cellular Component Annotations 2025 1.0 null Integral component of presynaptic membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.104 Lung adenocarcinoma_LUAD_TCGA-55-8089-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SKUT1 DepMap CRISPR Gene Dependency 1.0 6.26309 Rectum adenocarcinoma_READ_TCGA-DY-A1DD-01A-21R-A155-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FAU Pathway Commons Protein-Protein Interactions 1.0 null prostate_4c HPA Tissue Sample Gene Expression Profiles 1.0 1.23695 HIPK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56382 HNRNPU Pathway Commons Protein-Protein Interactions 1.0 null Gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 PMC8174725-ppat.1009603.s006.xlsx-neg_nsp3-ZSGvs_Untr-nsp3-ZSG_PATZ1 Rummagene Transcription Factor Associations 2026 1.0 null NOMO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35034 TTLL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.03314 NuA4 histone acetyltransferase complex GO Cellular Component Annotations 2023 1.0 null posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.08404 Eisosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.704 inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.46398 NCI-H345 COSMIC Cell Line Gene Mutation Profiles 1.0 null SNU739 DepMap CRISPR Gene Dependency 1.0 2.8883 A-375 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.950178 PMC12749419-41598_2025_28826_MOESM3_ESM.xlsx-RFT_iBody3_hexaplicate-Genes_MBD1 Rummagene Transcription Factor Associations 2026 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-8092-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KELLY CCLE Cell Line Gene CNV Profiles -1.0 -1.77595 ETHE1 Pathway Commons Protein-Protein Interactions 1.0 null posteroventral (inferior) parietal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.07335 PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_30min-Nearest_Ensembl_HSF1 Rummagene Transcription Factor Associations 2026 1.0 null PMC7789679-13287_2020_2062_MOESM3_ESM.docx-0-Supplementary_Table_1_MSC_secretome_following_healthy_CM_stimulation_MSC Rummagene Transcription Factor Associations 2026 1.0 null MESP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01087 Actin family InterPro Predicted Protein Domain Annotations 1.0 null H2BFS Pathway Commons Protein-Protein Interactions 1.0 null RPL23 Pathway Commons Protein-Protein Interactions 1.0 null Carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.259 496100529_HIP_no dementia_no TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.39094 HNRNPF Pathway Commons Protein-Protein Interactions 1.0 null specific GeneRIF Biological Term Annotations 1.0 null RPL19 Pathway Commons Protein-Protein Interactions 1.0 null TAGLN2 Pathway Commons Protein-Protein Interactions 1.0 null METTL8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41421 Brain Lower Grade Glioma_LGG_TCGA-DU-6396-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PPP2R1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.14774 EVI5L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59448 GSE226584,GSE226589_2_v_0_ezh2_human RummaGEO Gene Perturbation Signatures -1.0 null PMC8639438-41388_2021_1938_MOESM3_ESM.xlsx-ZNF545-IP_group-Gene_Name_ZFP82 Rummagene Transcription Factor Associations 2026 1.0 null CFPAC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06326 efo21 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.775 MAX JASPAR Predicted Transcription Factor Targets 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2900-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF587 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.0891 CDK1 Pathway Commons Protein-Protein Interactions 1.0 null DMS454 CCLE Cell Line Gene CNV Profiles -1.0 -1.39436 EEF1A1P5 Pathway Commons Protein-Protein Interactions 1.0 null PDZD8 Pathway Commons Protein-Protein Interactions 1.0 null OXER1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71094 ZW10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23988 GSE258991_5_v_0_enzalutamide_human RummaGEO Drug Perturbation Signatures -1.0 null PMC8481886-Table_1.xlsx-A_subsets-UC_MSC_MSC Rummagene Transcription Factor Associations 2026 1.0 null dorsorostral division of MFC (area 32) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.983599 POLR2A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6943-11A-01R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE131649_6_v_5_hemin_human RummaGEO Drug Perturbation Signatures -1.0 null TBC1D13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41185 HEC-1-A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.49123 496100355_HIP_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.99094 NCI-H1299 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.59119 Lung squamous cell carcinoma_LUSC_TCGA-77-6842-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inner CP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.26888 ZNF282 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 89.562 Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A655-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GNPAT Pathway Commons Protein-Protein Interactions 1.0 null Lung non-small cell carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.084 cellular_component GO Cellular Component Annotations 2015 1.0 null testis_4a HPA Tissue Sample Gene Expression Profiles 1.0 1.15671 PMC12956708-DataSheet1.xlsx-Supplementary_Table_6-Supplementary_Table_5_The_DEGs_from_sea_level_between_AMS_and_non-eAMS_group_of_GSE75665_TWIST2 Rummagene Transcription Factor Associations 2026 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8637-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE187006_0_v_1_valproic acid_human RummaGEO Drug Perturbation Signatures 1.0 null FOSL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.72191 647V CCLE Cell Line Gene CNV Profiles -1.0 -3.13766 RPL21 Pathway Commons Protein-Protein Interactions 1.0 null MYC ENCODE Transcription Factor Targets 1.0 null SNU-398 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.894471 SARS-BatSRBD_96Hour_23935999_GSE47961 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.31414 substantia nigra development GO Biological Process Annotations 2023 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-7832-01A-11R-2132-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE218819_3_v_4_kdm5b_human RummaGEO Gene Perturbation Signatures -1.0 null paralogs GeneRIF Biological Term Annotations 1.0 null ETV6_01_91 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.7391 GSE172019_2_v_8_rnf2_human RummaGEO Gene Perturbation Signatures 1.0 null SEC22B Pathway Commons Protein-Protein Interactions 1.0 null EBC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05697 GATA2 ENCODE Transcription Factor Targets 1.0 null UBE4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6429 YPEL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10176 Kidney Chromophobe_KICH_TCGA-KO-8406-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-E1-5311-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Curli COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.908 HCT-15 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.663 NSL complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.994 GSE214583,GSE214585_1_v_0_steap1_human RummaGEO Gene Perturbation Signatures 1.0 null kinase binding GO Molecular Function Annotations 2025 1.0 null MKN7 CCLE Cell Line Gene CNV Profiles -1.0 -1.40834 ARCN1 Pathway Commons Protein-Protein Interactions 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7437-11A-01R-2132-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null retina homeostasis GO Biological Process Annotations 2023 1.0 null KATO III Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.55709 KEAP1 Pathway Commons Protein-Protein Interactions 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SM-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ERF::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.4119 LS-411N COSMIC Cell Line Gene Mutation Profiles 1.0 null UBE2N Pathway Commons Protein-Protein Interactions 1.0 null VPS51 Pathway Commons Protein-Protein Interactions 1.0 null MJ DepMap CRISPR Gene Dependency 1.0 2.08455 ZNF835 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37121 primary auditory cortex (core)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.11901 Integral component of postsynaptic membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.965 RPLP0 Pathway Commons Protein-Protein Interactions 1.0 null Synaptic ribbon COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.008 raphe obscurus nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.990155 PMC8995879-Table_1.xlsx-exome_variants_MAF_0_01-Gencode_34_hugoSymbol_MAF Rummagene Transcription Factor Associations 2026 1.0 null NCI-H1838 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00483 GSE158969_1_v_0_trastuzumab_human RummaGEO Drug Perturbation Signatures -1.0 null TTC39B Pathway Commons Protein-Protein Interactions 1.0 null CHD3 Pathway Commons Protein-Protein Interactions 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-7573-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DDX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52068 ASF1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03153 pontobulbar body Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.966875 CKB Pathway Commons Protein-Protein Interactions 1.0 null HIST1H2BF Pathway Commons Protein-Protein Interactions 1.0 null PPP6R1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50781 RPL18A Pathway Commons Protein-Protein Interactions 1.0 null RERF-LC-FM COSMIC Cell Line Gene Mutation Profiles 1.0 null HIST3H2A Pathway Commons Protein-Protein Interactions 1.0 null BZW1 Pathway Commons Protein-Protein Interactions 1.0 null Male reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 PMC8481886-Table_1.xlsx-A_subsets-iMSC_fetal_MSC_UC_MSC_MSC Rummagene Transcription Factor Associations 2026 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GR-06A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null D283MED DepMap CRISPR Gene Dependency 1.0 3.23749 GSE203267_0_v_1_alkbh5_human RummaGEO Gene Perturbation Signatures -1.0 null Lung squamous cell carcinoma_LUSC_TCGA-94-A5I6-01A-21R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCA-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.80416 Ankyrin repeat-containing domain InterPro Predicted Protein Domain Annotations 1.0 null MX1 Pathway Commons Protein-Protein Interactions 1.0 null HCC4011 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.78794 Acute Myeloid Leukemia_LAML_TCGA-AB-2825-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE74251_2_v_1_decitabine_human RummaGEO Drug Perturbation Signatures 1.0 null Perturb_729_KD_ADAR_SRP293637 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.08939 RPL3 Pathway Commons Protein-Protein Interactions 1.0 null lateral tuberal nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.37731 ARHGAP8 Pathway Commons Protein-Protein Interactions 1.0 null Lower respiratory tract disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.051 E2F8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.8748 RPL27 Pathway Commons Protein-Protein Interactions 1.0 null Neuron projection COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 RPS7 Pathway Commons Protein-Protein Interactions 1.0 null DYNC1H1 Pathway Commons Protein-Protein Interactions 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7410-01A-21R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null medial superior olive Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.2074 NCI-H1623 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.950178 Lung squamous cell carcinoma_LUSC_TCGA-21-5783-01A-41R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC44 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.864708 Kidney Chromophobe_KICH_TCGA-KO-8413-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100453_HIP_possible Alzheimer's disease_no TBI_88_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.91806 Lung adenocarcinoma_LUAD_TCGA-91-6831-01A-11R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null tissue homeostasis GO Biological Process Annotations 2015 1.0 null HS-294T cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.08 RAN Pathway Commons Protein-Protein Interactions 1.0 null HT144SKINFV2 DepMap CRISPR Gene Dependency 1.0 2.12129 Bacterial biofilm matrix COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.906 Intestinal cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.018 endopiriform nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.26108 DUSP22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79056 TBC1D4 Pathway Commons Protein-Protein Interactions 1.0 null GSE193258,GSE193259_9_v_6_osimertinib_human RummaGEO Drug Perturbation Signatures -1.0 null NSF Pathway Commons Protein-Protein Interactions 1.0 null GSE162892_4_v_2_sox9_human RummaGEO Gene Perturbation Signatures -1.0 null P300-27268052-CHIP-SEQ-BCELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null RPL22 Pathway Commons Protein-Protein Interactions 1.0 null NCI-H1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.85225 PK-45H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.836481 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1M5-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83S-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Gastrointestinal system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.216 A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB1-F2del_18Hour_None_GSE43203 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.44072 TE-1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.591 PCCA Pathway Commons Protein-Protein Interactions 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-5326-01A-01R-1873-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null single-organism process GO Biological Process Annotations 2015 1.0 null RPL24 Pathway Commons Protein-Protein Interactions 1.0 null 93T449 DepMap CRISPR Gene Dependency 1.0 4.48345 ZNF189 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.2813 GSE242290_1_v_0_glutathione_human RummaGEO Drug Perturbation Signatures 1.0 null Lung adenocarcinoma_LUAD_TCGA-78-7145-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ACTR3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.74825 GSE227592_13_v_1_adar_human RummaGEO Gene Perturbation Signatures -1.0 null CST6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85033 496100409_FWM_no dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.05674 Prostate gland epithelium TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Prostate adenocarcinoma_PRAD_TCGA-HC-7738-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KCNG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58748 ovary GTEx Tissue Gene Expression Profiles -1.0 -1.04397 HIST1H2AH Pathway Commons Protein-Protein Interactions 1.0 null 2q21 1 copy number variation syndrome WikiPathways Pathways 2024 1.0 null ACSL5 Pathway Commons Protein-Protein Interactions 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A8ID-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TCFL5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68842 posterior (caudal) superior temporal cortex (area 22c)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.48358 Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7072-01A-21R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Polymeric cytoskeletal fiber COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 Sarcoma_SARC_TCGA-DX-A7EM-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7422-01A-21R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC8437976-41416_2021_1470_MOESM2_ESM.xls-List_of_MAF_in_SNP_Rectum-Hugo_Symbol_MAF Rummagene Transcription Factor Associations 2026 1.0 null Peroxisomal membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.756 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5698-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null membrane-bounded vesicle GO Cellular Component Annotations 2015 1.0 null Bosentan DeepCoverMOA Drug Mechanisms of Action 1.0 0.47 POLR2A_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null VTA1 Pathway Commons Protein-Protein Interactions 1.0 null Supramolecular complex COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 Prostate-luminal cell of prostate epithelium Tabula Sapiens Gene-Cell Associations 1.0 3.96647 Reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.331 SORD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86667 C1orf115 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76829 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6953-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ANP32E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4171 Tivozanib DeepCoverMOA Drug Mechanisms of Action 1.0 0.58 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q6-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LGALS3 Pathway Commons Protein-Protein Interactions 1.0 null SLC25A1 Pathway Commons Protein-Protein Interactions 1.0 null RCC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87317 SNU-81 COSMIC Cell Line Gene Mutation Profiles 1.0 null DMS 454 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08471 RAB6A Pathway Commons Protein-Protein Interactions 1.0 null RPSA Pathway Commons Protein-Protein Interactions 1.0 null encodes GeneRIF Biological Term Annotations 1.0 null KELLY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.88784 PMC6225799-annrheumdis-2018-213524supp003.xlsx-Activated-state-LPS-Gene_Symbol_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null CDCA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39502 anatomical structure development GO Biological Process Annotations 2015 1.0 null MHH-PREB-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.25655 ZNF75A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 116.226 SMG6 Pathway Commons Protein-Protein Interactions 1.0 null Intrinsic component of synaptic membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.743 cell part LOCATE Curated Protein Localization Annotations 1.0 null KIAA0368 Pathway Commons Protein-Protein Interactions 1.0 null RPS23 Pathway Commons Protein-Protein Interactions 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MC-06A-12R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null paraventricular nucleus of hypothalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.946639 GSE117212,GSE117214_0_v_1_zbtb1_human RummaGEO Gene Perturbation Signatures -1.0 null GSE130401_4_v_3_trametinib_human RummaGEO Drug Perturbation Signatures -1.0 null Actin cytoskeleton COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 EEF1A2 Pathway Commons Protein-Protein Interactions 1.0 null GSE193157_0_v_1_chloroquine_human RummaGEO Drug Perturbation Signatures -1.0 null ZNF740 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 146.718 TCF4 ChEA Transcription Factor Targets 1.0 null TRIM28 Pathway Commons Protein-Protein Interactions 1.0 null VASN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60564 PMC12069319-Table1.xlsx-OCAB_p40_BirA-Gene_Symbol_POU2AF1 Rummagene Transcription Factor Associations 2026 1.0 null CYTH2 Pathway Commons Protein-Protein Interactions 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-90-A4ED-01A-31R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null amygdaloid complex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.01521 GSE162892_4_v_2_isox_human RummaGEO Drug Perturbation Signatures -1.0 null SRP9 Pathway Commons Protein-Protein Interactions 1.0 null SPI1-23127762-K562-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null LLGL2 Pathway Commons Protein-Protein Interactions 1.0 null primary motor cortex (area M1, area 4)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.867043 NCI-H889 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.950178 orbital frontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.64971 Lung adenocarcinoma_LUAD_TCGA-44-2657-11A-01R-1758-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE213410_0_v_3_calcitriol_human RummaGEO Drug Perturbation Signatures -1.0 null KPL-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.2861 ARHGAP1 Pathway Commons Protein-Protein Interactions 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IJ-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PLEK2 Pathway Commons Protein-Protein Interactions 1.0 null GSE216274,GSE216292_4_v_2_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null CSNK2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22257 NCI-H810 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.83198 posteroventral (inferior) parietal cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.32028 amygdaloid complex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.29022 lateral orbital frontal cortex (area 12/47) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.60811 SARS-CoV_0Hour_23935999_GSE47960 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.53144 GSE200839,GSE233826_5_v_0_tnrc18_human RummaGEO Gene Perturbation Signatures 1.0 null primary auditory cortex (core)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.03675 SEPT7 Pathway Commons Protein-Protein Interactions 1.0 null MYO1E Pathway Commons Protein-Protein Interactions 1.0 null GSE131649_6_v_10_hemin_human RummaGEO Drug Perturbation Signatures -1.0 null Axon COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 PRKAB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53014 HT Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.72305 ZBTB6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.925 Prostate adenocarcinoma_PRAD_TCGA-HC-7078-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null callosal sling Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.836014 ENO1 Pathway Commons Protein-Protein Interactions 1.0 null PMC8770127-41586_2021_4246_MOESM14_ESM.xlsx-Extended_Figure_5d-FOXA1_interactome_FOXA1 Rummagene Transcription Factor Associations 2026 1.0 null Endomembrane system COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 1.495 SW579 DepMap CRISPR Gene Dependency 1.0 2.30284 AR-19668381-PC3-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Female reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.303 PMC8709578-elife-69843-supp4.xlsx-HSF1_ChIP-seq_peaks-Gene_Name_HSF1 Rummagene Transcription Factor Associations 2026 1.0 null GSE216043_7_v_8_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.11735 MXD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45704 FGF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45021 Actin filament COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 MMAC DepMap CRISPR Gene Dependency 1.0 10.0039 laterorostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.961 Lung squamous cell carcinoma_LUSC_TCGA-77-8145-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TCF4-23295773-U87-HUMAN ChEA Transcription Factor Targets 2022 1.0 null CYTH3 Pathway Commons Protein-Protein Interactions 1.0 null HIST2H2AC Pathway Commons Protein-Protein Interactions 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8317-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC8724844-bt-30-1-98-supple2.xlsx-GO_BP-TFAP4_TFAP4 Rummagene Transcription Factor Associations 2026 1.0 null striatum_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.68499 HNRNPR Pathway Commons Protein-Protein Interactions 1.0 null inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.39195 PMC12749419-41598_2025_28826_MOESM3_ESM.xlsx-RFT_iBody3_triplicate-Genes_MBD1 Rummagene Transcription Factor Associations 2026 1.0 null PITPNB Pathway Commons Protein-Protein Interactions 1.0 null PMC12289921-41467_2025_62099_MOESM4_ESM.xlsx-MI-2-80-Gene_Symbol_MITF Rummagene Transcription Factor Associations 2026 1.0 null Prostate adenocarcinoma_PRAD_TCGA-G9-6496-11A-01R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null striatum_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.859292 cerebellar cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.62457 VCAP DepMap CRISPR Gene Dependency 1.0 2.66106 hsa-miR-4251 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 NCIH209 CCLE Cell Line Gene CNV Profiles -1.0 -1.40092 ventrolateral prefrontal cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.29618 Perturb_8648_KO_NKX25_SRP287180 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 SAR1A Pathway Commons Protein-Protein Interactions 1.0 null PMC6639357-41467_2019_11150_MOESM4_ESM.xlsx-SupTab1_Activated_genes_diffex-Supplementary_Data_1_Fold_change_and_p-value_of_all_activated_protein_coding_genes_upon_DNMT1-KO_DNMT1 Rummagene Transcription Factor Associations 2026 1.0 null inferior nucleus of pulvinar Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.951018 M059K Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01376 CRAT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23729 Sarcoma_SARC_TCGA-X6-A7WA-01A-12R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Gonadal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.36 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A0VN-01A-21R-A10U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MKN-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.28081 MM253 DepMap CRISPR Gene Dependency 1.0 2.0741 GSE216043_3_v_5_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null SP in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.04475 KMS26 CCLE Cell Line Gene CNV Profiles -1.0 -1.59452 primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.994688 XRCC6 Pathway Commons Protein-Protein Interactions 1.0 null EPZ004777 DeepCoverMOA Drug Mechanisms of Action 1.0 0.4 membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null RPS3A Pathway Commons Protein-Protein Interactions 1.0 null RPL26 Pathway Commons Protein-Protein Interactions 1.0 null GSE193258,GSE193259_9_v_15_osimertinib_human RummaGEO Drug Perturbation Signatures -1.0 null CEBPA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.71397 Kidney Chromophobe_KICH_TCGA-KN-8434-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KARPAS-620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18222 RHO GTPase cycle Reactome Pathways 2024 1.0 null nitric-oxide synthase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.963 PMC12271601-mmc2.xlsx-OUT_cells_02-Gene_Symbol_TCF23 Rummagene Transcription Factor Associations 2026 1.0 null Uterine Carcinosarcoma_UCS_TCGA-N8-A4PN-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-570 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 ventrolateral prefrontal cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.965616 Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HQ-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LRRC32 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52963 Acute Myeloid Leukemia_LAML_TCGA-AB-3002-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SW 1417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.392 F36P CCLE Cell Line Gene CNV Profiles -1.0 -1.97044 Prostate adenocarcinoma_PRAD_TCGA-YL-A8SQ-01B-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Transnitrosylase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.522 Edinger-Westphal nucleus (accessory oculomotor nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.64432 POLE4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31819 RPL7 Pathway Commons Protein-Protein Interactions 1.0 null NCI-H1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20114 NUDT19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20843 GSE164505,GSE164506_3_v_2_indisulam_human RummaGEO Drug Perturbation Signatures 1.0 null JMSU1 CCLE Cell Line Gene CNV Profiles 1.0 1.55026 SPI1 ChEA Transcription Factor Targets 1.0 null SNU-175 COSMIC Cell Line Gene Mutation Profiles 1.0 null ACADVL Pathway Commons Protein-Protein Interactions 1.0 null Lung carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.068 PDIA6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2039 TDRD3-21172665-MCF-7-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-63-7023-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-7211-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary motor cortex (area M1, area 4)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.07772 Lung squamous cell carcinoma_LUSC_TCGA-34-A5IX-01A-12R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ACBD5 Pathway Commons Protein-Protein Interactions 1.0 null Large intestine cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.02 NCCIT COSMIC Cell Line Gene Mutation Profiles 1.0 null SK-MES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00483 NFIL3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.4683 neural nucleus development GO Biological Process Annotations 2015 1.0 null GNG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02421 MZ in dorsomedial parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.3364 LMX1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46887 Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7382-01A-11R-2132-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZC3H15 Pathway Commons Protein-Protein Interactions 1.0 null SELENOV CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8657 CCDC90B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.77832 icSARS CoV_7Hour_None_GSE37827 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.63733 SARNP Pathway Commons Protein-Protein Interactions 1.0 null primary motor cortex (area M1, area 4)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.73267 testis_7a HPA Tissue Sample Gene Expression Profiles 1.0 1.17579 HCC1263 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.984438 prostate_4b HPA Tissue Sample Gene Expression Profiles 1.0 1.14889 RPS15A Pathway Commons Protein-Protein Interactions 1.0 null 496100381_HIP_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.52368 regulation of biological quality GO Biological Process Annotations 2015 1.0 null GPT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46736 OUMS-23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.950178 POLQ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85922 RALA Pathway Commons Protein-Protein Interactions 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3C7-06A-11R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_H1-hESC_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null ELOC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06848 DTYMK Pathway Commons Protein-Protein Interactions 1.0 null primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.921382 MBX-2982 DeepCoverMOA Drug Mechanisms of Action 1.0 0.48 RPL4 Pathway Commons Protein-Protein Interactions 1.0 null ZBED2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.6962 Nasopharynx epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.736 prostate GTEx Tissue Gene Expression Profiles 1.0 2.18987 EFM-192C Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08387 GSE164874_5_v_12_prednisolone_human RummaGEO Drug Perturbation Signatures -1.0 null HIST1H2BB Pathway Commons Protein-Protein Interactions 1.0 null SSC4D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29846 CES2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87037 MOV10 Pathway Commons Protein-Protein Interactions 1.0 null RBMX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40668 ventral medial nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.98352 indusium griseum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.15068 GSE102505_6_v_2_tunicamycin_human RummaGEO Drug Perturbation Signatures 1.0 null RPL13A Pathway Commons Protein-Protein Interactions 1.0 null PFKL Pathway Commons Protein-Protein Interactions 1.0 null Lung adenocarcinoma_LUAD_TCGA-97-7553-01A-21R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RPL8 Pathway Commons Protein-Protein Interactions 1.0 null OCIM2 DepMap CRISPR Gene Dependency 1.0 2.68809 GSE224004,GSE224005_0_v_8_chd4_human RummaGEO Gene Perturbation Signatures 1.0 null SLC35E4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.77809 GOLGA6L9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26668 Microbody membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.755 layer I of piriform cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.964015 MYC_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-BI-A0VR-01A-11R-A10U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null plasma membrane LOCATE Curated Protein Localization Annotations 1.0 null 22RV1 CCLE Cell Line Gene CNV Profiles -1.0 -2.11544 NTPCR Pathway Commons Protein-Protein Interactions 1.0 null SLC7A8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85958 SPIB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 75.8358 PANC 02.03 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.900023 Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1PV-01A-11R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PKM Pathway Commons Protein-Protein Interactions 1.0 null METRNL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11368 HONE-1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.717 substantia nigra development GO Biological Process Annotations 2015 1.0 null anatomical structure homeostasis GO Biological Process Annotations 2015 1.0 null CTNNB1 Pathway Commons Protein-Protein Interactions 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-H6-8124-11A-01R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CNN2 Pathway Commons Protein-Protein Interactions 1.0 null Lung adenocarcinoma_LUAD_TCGA-05-5423-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HADHA Pathway Commons Protein-Protein Interactions 1.0 null prostate_4a HPA Tissue Sample Gene Expression Profiles 1.0 1.24397 thyroid_5b HPA Tissue Sample Gene Expression Profiles -1.0 -0.854718 Liver hepatocellular carcinoma_LIHC_TCGA-RG-A7D4-01A-12R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sarcoma_SARC_TCGA-SG-A6Z4-01A-22R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary auditory cortex (core)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.840755 Brain Lower Grade Glioma_LGG_TCGA-DB-5275-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RPL27A Pathway Commons Protein-Protein Interactions 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7046-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8310-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SMARCA4 Pathway Commons Protein-Protein Interactions 1.0 null HIST2H2AA4 Pathway Commons Protein-Protein Interactions 1.0 null