association	dataset	threshold value	standardized value
DPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03948
MTG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45037
HCC44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.883311
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.7129
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.7267
TUBB	Pathway Commons Protein-Protein Interactions	1.0	null
CHRNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20512
AGFG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6325
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.993616
SERINC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92682
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.63282
salivary gland	GTEx Tissue Gene Expression Profiles	-1.0	-1.24376
PLPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73913
ZNF747	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0199
GSE166783_8_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100414_TCx_probable Alzheimer's disease_no TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03296
PARN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72239
TERF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39831
HIGD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5511
BFAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36672
496100350_FWM_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.52895
TLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65833
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.952884
EPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20951
PMC10746608-427_2023_709_MOESM5_ESM.xlsx-NR3C1_partners-NR3C1_known_protein_partners_according_to_BioGrid_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
PPARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.9643
ZBTB38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88101
PMC8040704-jcav12p2673s2.xlsx-Up-regulated_genes_in_EBF1-Unnamed_0_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8102188-41375_2021_1231_MOESM4_ESM.xlsx-t_som_AA_healthy-Unnamed_7_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
extracellular space	GO Cellular Component Annotations 2015	1.0	null
SW 837	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.24585
RPRML	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28713
Actin filament	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
ZNF138	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06558
a549	HPA Cell Line Gene Expression Profiles	-1.0	-1.05471
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4002
HIST3H3	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF443	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67201
DUSP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28092
MZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.41463
496100635_HIP_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.00256
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.00163
IKBKG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70684
FAM229A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63719
DMAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15273
HT-144	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.950488
COLO-684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
YWHAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80493
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.943423
CLDN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21551
PTGES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66312
LEFTY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61054
SP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.946691
LEUTX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63518
MED27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70863
TP53BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36172
CMTM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67707
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.993616
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.867555
NIPA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68454
LOXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6972
HEY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75274
BD-04-NG34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.273501
prostate_4c	HPA Tissue Sample Gene Expression Profiles	1.0	1.31826
Ankyrin repeat-containing domain	InterPro Predicted Protein Domain Annotations	1.0	null
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30227
HEY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3186
layer IIIu of area 35r	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22281
EML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28329
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04426
TENM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30462
UBAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8467
MEF2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12226
ENAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32025
MARK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38034
MEF2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8383
MDM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10934
TMEM185A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60615
POU4F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63321
ELOVL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91424
lateral subdivision of BNST	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04309
496100449_PCx_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.25402
GSE238018_3_v_0_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
midbrain reticular formation	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.55358
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
PRSS53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72242
EIF4A3	Pathway Commons Protein-Protein Interactions	1.0	null
496100440_FWM_possible Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.27308
extracellular vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.057922
H1-4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71636
NKTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3035
GSE113005_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CF-87-AS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.295634
IZ in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.48365
NECAB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5742
parathyroid gland	HPA Tissue Protein Expression Profiles	-1.0	-0.779376
SRPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90611
testis_7f	HPA Tissue Sample Gene Expression Profiles	1.0	1.32331
ZNF524	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.08161
HIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32764
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09484
496100501_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.55192
YIF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85091
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.34208
GSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09111
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0744
OACP4C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H4 histone acetyltransferase complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
retina homeostasis	GO Biological Process Annotations 2023	1.0	null
GSE62974_1_v_0_epas1_human	RummaGEO Gene Perturbation Signatures	1.0	null
organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
outer CP in (rostral) midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.958079
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56529
PRPF39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9343
VAX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34868
P4HTM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31354
cerebellar vermis	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.51402
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3231
POTEI	Pathway Commons Protein-Protein Interactions	1.0	null
extracellular region part	GO Cellular Component Annotations 2015	1.0	null
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.926416
RNF126	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11025
CSRNP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52489
RPL23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64262
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18506
GALM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20911
TRIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88835
AQP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68371
CBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08332
ZNF646	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78416
IZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08393
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-0.779376
RPP25L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47478
GSE160304,GSE163392_0_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EW-24	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cell	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.24505
R3HDM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46643
HIST1H3B	Pathway Commons Protein-Protein Interactions	1.0	null
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04592
GTF3C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.92895
JD-81-YX02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.34842
KPL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35925
POTEE	Pathway Commons Protein-Protein Interactions	1.0	null
GNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50999
GSTP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87093
KIAA1586	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68564
RDH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35328
DKK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60719
METTL25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36561
HTR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71697
SR-786	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.956431
GLYR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46262
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09484
PD-70-VS77_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.654193
DNM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18047
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53996
PIK3R3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05113
KXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4892
DNAJC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51474
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05908
neuron projection morphogenesis	GO Biological Process Annotations 2025	1.0	null
EGR4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	87.0407
ATR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83225
TOP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4309
NCI-H1417	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18506
MAT2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38198
PMC12271601-mmc2.xlsx-OUT_cells_03-Gene_Symbol_TCF23	Rummagene Transcription Factor Associations 2026	1.0	null
BARHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.86919
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20272
ZSCAN31	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.5496
SLIRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44164
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ACLY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37287
PMC12234789-41467_2025_61560_MOESM3_ESM.xlsx-Supplementary_data_1-Only_YY1_IP-MS_YY1	Rummagene Transcription Factor Associations 2026	1.0	null
TSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27181
DA-10-HD17_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.35442
FBXO38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57922
NuA4 histone acetyltransferase complex	GO Cellular Component Annotations 2025	1.0	null
GSTO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60992
SLC38A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64104
GSE102505_5_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FLOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06219
POLR2M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40433
FOXP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79554
GSE120756_2_v_9_tet2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FB-49-NW04_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.229411
LAMTOR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82386
METTL7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91876
CTBP2	Pathway Commons Protein-Protein Interactions	1.0	null
POLL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.25083
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7438
LDHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70549
KLK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85734
INSIG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95879
GA-88-CF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.374029
ZNF790	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54608
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.73034
MHH-PREB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZFYVE27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62777
XPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30082
HC-74-HM63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.34679
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.606
CBX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23854
limitans nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.87829
INO80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02775
Endometrial gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.509
SRSF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21403
SOX17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43616
cytoskeleton	GO Cellular Component Annotations 2025	1.0	null
ATG9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60037
SETDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06791
HS 255.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.85505
inferior olive, principal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27759
DPH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74511
NTMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92402
DBI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50411
ITGAV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86926
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.8123
DCTD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89637
SPIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71769
ADAM33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80357
KMH-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ACBD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7175
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.89109
TWIST1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.9541
PMC12271601-mmc2.xlsx-OUT_cells_01-Gene_Symbol_TCF23	Rummagene Transcription Factor Associations 2026	1.0	null
HEXIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65621
BD-69-GX17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.262781
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.40347
RAPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.72729
KIF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24426
DHRS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5505
SU-DHL-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.64384
ALG12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92293
TSPAN33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03293
PNPLA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14675
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46096
GSE160817_4_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.88172
496100559_FWM_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.75339
PLEKHH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00151
GSE183101_0_v_1_hvcn1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cytoplasm	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
TFEB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49438
HCT-116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cd8 cells	HPM Cell Type and Tissue Protein Expression Profiles	1.0	0.929423
ZBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94666
ZNF71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.00824
PMC12069319-Table1.xlsx-OCAB_p40_BirA-Gene_Symbol_POU2AF1	Rummagene Transcription Factor Associations 2026	1.0	null
COLO-704	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.44478
BEST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72096
TCF21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9369
AP3S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87622
ES-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.843436
GORAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04719
WE-43-PZ45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.26661
parataenial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20949
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.9142
axonogenesis	GO Biological Process Annotations 2025	1.0	null
G-402	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.96553
extracellular vesicular exosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
SNX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43547
TASOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39955
TXNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24028
TBCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77542
PRIMPOL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07527
ALG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15988
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.46534
EIF4EBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94687
ZNF549	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.7526
THEMIS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21655
UBAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29869
DUS3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20478
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22282
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6943
THRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71734
GATA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28351
THEM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63103
CPD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6794
PNRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2445
OLIG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13044
cerebellum	HPA Tissue Protein Expression Profiles	-1.0	-0.779376
EGR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	90.9224
RASSF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75948
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.86312
ZIK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29788
TMEM81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05968
DMS-79	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MEF2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71949
ENTPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4305
extracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.906522
JD-44-KF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.352736
GTF2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68862
NFYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0484
DMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51666
ntera2	HPA Cell Line Gene Expression Profiles	-1.0	-1.05471
TUFM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14783
CNPY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42252
polymeric cytoskeletal fiber	GO Cellular Component Annotations 2025	1.0	null
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10552
CTBP1	Pathway Commons Protein-Protein Interactions	1.0	null
IGROV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
LBHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06122
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.919998
QE-79-XO29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.560127
PYGB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84002
axon development	GO Biological Process Annotations 2025	1.0	null
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07221
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0171
HD-51-KD29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.05586
HIKESHI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24025
ZNF551	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33037
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.87005
PMC7415402-oncotarget-11-2995-s004.xlsx-EWS-FLI1_Type_1_vs_Type_2-Gene_Symbol_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.10862
BLACAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71428
F2RL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36343
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.26426
EGR3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	94.1249
LA-42-ER00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.296623
CAOV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.24383
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4705
TRRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24293
CSPG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05001
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.892517
TRIM54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.7385
CAPN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53962
heart muscle	HPA Tissue Gene Expression Profiles	1.0	0.864922
HES6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7117
WRAP73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49276
KRTAP13-4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09157
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.62172
AC-84-QG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.547658
Cytoplasmic vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.31
FARAGE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.5523
NFIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09165
TE-9	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZC3H14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32969
ATP6V1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01301
DPP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12565
MRPL53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50691
SALL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82052
PMC8242083-41467_2021_24064_MOESM4_ESM.txt--HSF1_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
FDPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57522
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0396
ESX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32437
OXLD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28609
GALNT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8805
testis_7b	HPA Tissue Sample Gene Expression Profiles	1.0	1.58339
SIRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00861
DLX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.98905
ZFP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14469
JHH-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.5054
BARD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72461
PFDN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03715
KMS-28PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.25061
ATG9A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35346
MYCN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2794
COPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21431
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.16799
CCDC124	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48373
paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.965432
regulation of biological quality	GO Biological Process Annotations 2015	1.0	null
ZBTB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48334
UBE3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96452
ZNF708	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64904
HUTU-80	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MAGOH	Pathway Commons Protein-Protein Interactions	1.0	null
GSE238018_3_v_2_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC6A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06378
FAM210B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97157
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.917075
ACTG2	Pathway Commons Protein-Protein Interactions	1.0	null
Actin cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
TMC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21365
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5119
NR1H4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57946
PAPOLB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84448
PSKH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55992
SH-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DHX30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93615
ovary	HPA Tissue Protein Expression Profiles	-1.0	-0.779376
inner SZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.155
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.52305
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
KRT18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22966
GSE129241_3_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DHX32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31872
PCDHB14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9368
RNF19B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5644
PRUNE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44915
BT-20	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.62509
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.84242
SLC19A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62875
G22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.884911
BHLHE23	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4846
RBM39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82096
CTDNEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78223
GTPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79085
MOLP-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.07394
RXRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74023
SAMD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69978
ZNF268	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97707
PI4K2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7404
ESPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49004
UBALD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17344
GCM2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0656
HOXD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25644
STRADB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41483
HT-1376	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.832245
NCI-SNU-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TRAM1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14098
COX7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97754
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03594
SERINC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36153
TNNI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1451
GSE238018_3_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
UFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82697
APOBEC3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2701
SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.836154
GSE238018_3_v_5_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TMEM41B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77594
homeostatic process	GO Biological Process Annotations 2015	1.0	null
Ankyrin repeat	InterPro Predicted Protein Domain Annotations	1.0	null
ICAM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30406
SERPINE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41446
hel	HPA Cell Line Gene Expression Profiles	-1.0	-1.05471
GSE198228,GSE198245_0_v_2_apoe_human	RummaGEO Gene Perturbation Signatures	-1.0	null
inner CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33419
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.975562
kinase binding	GO Molecular Function Annotations 2025	1.0	null
TMBIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95519
GSE102505_5_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.9142
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.67107
CXCR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79616
KLF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.94499
UACC-812	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC9805873-Supp_Data.xlsx-dCas9-SALL1-SDS3_SEL1L_pool-id_SALL1	Rummagene Transcription Factor Associations 2026	1.0	null
RNF115	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37104
PNPLA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9134
SCPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32212
RO82-W-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
an3ca	HPA Cell Line Gene Expression Profiles	1.0	0.890363
CCDC22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28801
RCC-JF	COSMIC Cell Line Gene Mutation Profiles	1.0	null
thyroid gland	HPA Tissue Protein Expression Profiles	-1.0	-0.779376
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.889112
Actin, conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.86624
TAF5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03037
HOXD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52224
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.901113
496100492_TCx_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.73575
TRIM36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65407
ACTR3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74825
ACSL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57156
UBE2N	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33787
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.59824
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61673
UBE2V2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34589
ASPSCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6516
PRDX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31743
KIF20B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52762
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.978478
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.86392
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18506
GSE166783_4_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HSPE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37791
PLOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49413
NSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10706
CAOV-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FB-66-UU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.225753
PLD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91575
AGPAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.371
JC-06-ED36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.71024
UBE2W	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9113
MCM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34846
GA-88-CF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.657497
Vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.2
protein kinase binding	GO Molecular Function Annotations 2025	1.0	null
outer CP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.834248
ZFP62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46573
outer CP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24841
MOB3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75314
PGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54551
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.91569
KLF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26999
UQCC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77618
OTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.08323
WWP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51455
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.27218
Supramolecular fiber	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GC-04-UF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.754224
NFYA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68629
testis_7a	HPA Tissue Sample Gene Expression Profiles	1.0	1.19308
CCDC77	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3101
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26339
LRRC47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48791
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.2724
NR1I2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.63251
HO-1-N-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AC-05-MR83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.224049
CAMKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.75574
496100478_HIP_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.33972
Jiii	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.5
HYOU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76707
PMC7415402-oncotarget-11-2995-s004.xlsx-EWS-FLI1_Type_1_vs_Type_3-Gene_Symbol_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
ANXA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38179
MRPL14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26972
AP3M2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45016
23132-87	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AMIGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07751
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04996
ODF2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15979
Edinger-Westphal nucleus (accessory oculomotor nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.53522
SOHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.5287
TCEAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71737
OLIG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7198
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.915181
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
NFYC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22722
Supramolecular complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
DPY19L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34019
CYP27C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77375
ZBED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86544
UF-27-HS98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	7.4462
prostate	HPA Tissue Gene Expression Profiles	1.0	2.23434
anterior amygdaloid area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.79575
JUNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29946
PMC7415402-oncotarget-11-2995-s004.xlsx-EWS-FLI1_Type_2_vs_Type_3-Gene_Symbol_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
FN3KRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43573
Oviduct epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.185
MAN1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82251
H4/H2A histone acetyltransferase complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
extracellular vesicular exosome	GO Cellular Component Annotations 2015	1.0	null
EEF1A1	Pathway Commons Protein-Protein Interactions	1.0	null
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35347
GSE195514_0_v_1_stk25_human	RummaGEO Gene Perturbation Signatures	1.0	null
CDS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33844
496100556_TCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.58295
CD-35-BD44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.205075
TLE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38978
TSG101	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08244
KMS-12-BM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.22708
ADAMTS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47517
CF-65-GU65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.57054
SEC61G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31311
KCNIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.92743
MAP3K10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28942
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TIRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6991
GSE99687_2_v_1_smad5_human	RummaGEO Gene Perturbation Signatures	1.0	null
MRRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04924
G84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.43834
TLCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95651
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.370191
Skin - Sun Exposed (Lower leg)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.784404
LYSMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07034
H6PD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65759
HS 683	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.37438
Cells - Cultured fibroblasts	GTEx Tissue Gene Expression Profiles 2023	1.0	1.13178
QE-79-XO29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.671835
retina homeostasis	GO Biological Process Annotations 2015	1.0	null
CA-SKI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HMG20B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91977
BORA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18876
ATXN7L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91451
GSE149621_3_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.933096
actin cytoskeleton	GO Cellular Component Annotations 2025	1.0	null
RECQL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0363
REPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65866
golgi apparatus	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
liver	GTEx Tissue Gene Expression Profiles	-1.0	-0.831972
LGR4	Pathway Commons Protein-Protein Interactions	1.0	null
SPATA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54531
AC-28-RT00_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.339383
HAGH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81742
CLIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64742
HES5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9716
JUND	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59694
496100318_PCx_probable Alzheimer's disease_TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.46228
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12603
ZNF583	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74211
OPM-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BC-54-ON71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.631891
Secretory granule lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.366
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29771
NT5DC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22296
bewo	HPA Cell Line Gene Expression Profiles	1.0	0.894321
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03594
496100351_FWM_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.90645
LRRC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32714
VWDE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81369
MYH14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44772
IFT25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10801
PHTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01363
TMEM160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66574
LONRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31427
ZBTB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27207
MYO19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46564
RAB23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30757
GALNT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84285
prostate_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.0702
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7942
IRF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1051
DB-51-UO66_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.312486
TXK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41458
FAM50A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84378
PITHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7161
LAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5308
extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
anterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06073
SLFN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41334
RSC1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86179
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.3396
CC-20-ZO24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.231026
NMRAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7098
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24074
biological regulation	GO Biological Process Annotations 2015	1.0	null
COLO 679	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.39418
LIMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32176
TPM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71709
PMC8040704-jcav12p2673s2.xlsx-Up-regulated_genes_in_EBF1-Unnamed_5_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
FLI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42195
TAPBPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50104
HB-06-WU12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.424426
DLD-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.77637
PSEN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88989
KCTD17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91449
ZNF787	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.24547
NDUFS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2323
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0171
DMAC2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28399
ANKRD50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99563
AD-16-HL96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.33337
DHODH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06488
PAX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52957
HAND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35932
SZ in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.878595
GSE163240_2_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BHLHE40	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.5808
ZNF627	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10284
Endomembrane system	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.495
WB-48-EF24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	4.18899
Actin family	InterPro Predicted Protein Domain Annotations	1.0	null
cell part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
G141	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0574
RAD54L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9535
extracellular organelle	GO Cellular Component Annotations 2015	1.0	null
PTPRZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58808
D-502MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZFPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22927
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.853894
RAMAC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26649
intracellular part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.922715
GON7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.74069
STPG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37937
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30818
SNRPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23911
SCN4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18705
NOL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2754
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.127
496100375_FWM_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.997
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.73034
BCAP31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.89928
GTF2A1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25113
UC-21-PY73_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.21428
FASTKD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20835
KMS-28PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.66768
OVCA-5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.613
MVB12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38688
TUBA1C	Pathway Commons Protein-Protein Interactions	1.0	null
INO80E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.97589
DDX42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37235
DCAF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46887
HD-51-KD29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.972802
NCI-H2722	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.06424
Polymeric cytoskeletal fiber	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
NDST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05848
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.926416
intracellular	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12603
PRKCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49644
KLF14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	86.8174
Df	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.968
WDR5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63597
TNFRSF12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19199
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCA-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.88249
GSE135400_1_v_0_kdm1b_human	RummaGEO Gene Perturbation Signatures	1.0	null
FB-66-UU47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.937502
RAD23A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63294
cellular_component	GO Cellular Component Annotations 2015	1.0	null
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33582
AD-16-HL96_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	3.02737
TMEM63A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31952
LK-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KLK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18269
PTPN13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98953
ZCCHC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47826
PCDHB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49937
HINT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80528
SFXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99654
LIN7C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69326
CFAP97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53086
ZNF256	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54893
ARL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58795
MAX::MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7143
EIF3E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6001
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.915181
Hep-G2/C3A cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.177
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9769
ZNF410	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.14693
MYPOP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69663
MRPS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46025
TCFL5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.5869
ADCY6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52906
EPAS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.9078
T98G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04043
CCNE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04909
extracellular region part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CDK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97479
DPP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6784
HCC-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1694	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MFSD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93614
PIK3R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86333
PMC12381255-41389_2025_576_MOESM2_ESM.xlsx-Progenitor_SRCAP-1879-Gene_SRCAP	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM199	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68251
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46235
HT-1080	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.831247
FOSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07889
COG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93575
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.04377
IDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01472
prostate_4b	HPA Tissue Sample Gene Expression Profiles	1.0	1.00431
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.57882
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.11761
ZSCAN5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53968
EHF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92793
TDRD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40874
ZNF341	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70018
CLUH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97312
ZFP57	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.861
Axon	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
callosal sling	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.860294
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.920937
TTLL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40801
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18358
FE-10-KQ78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.343868
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.902187
CHRD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84434
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.56796
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24071
PCNX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74889
PPARG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83096
FGF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17104
TMEM238	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85763
NUDT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58209
PMC12069319-Table1.xlsx-OCAB_p35_BirA-Gene_POU2AF1	Rummagene Transcription Factor Associations 2026	1.0	null
UGGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09446
C19orf25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89703
ALKBH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75387
METTL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44323
DISP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52616
EF-74-KW12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.20856
SUPT6H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68747
RREB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6995
MARF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10855
MSH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73552
ENDOU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84522
SBK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74028
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0171
TC-71	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04387
ADM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14557
PJVK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61496
TRMT2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49963
GPATCH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32921
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SLTM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08757
CCDC117	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65535
HSFX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47124
SK-MEL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NOP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82855
CCDC103	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5438
Focal segmental glomerulosclerosis 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.765
PCNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17653
SRRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74395
mitochondrion	LOCATE Predicted Protein Localization Annotations	1.0	null
testis	HPA Tissue Protein Expression Profiles	-1.0	-0.779376
QTRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7729
UXS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30313
ZNF714	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10606
MYCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25429
Eht	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.698
PFN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05981
extracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
RPMI-7951	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04043
ZBTB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26647
GOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25211
p2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.82
C1orf198	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93591
PMC12289921-41467_2025_62099_MOESM5_ESM.xlsx-MI-2-80-Gene_Symbol_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
TUBA1A	Pathway Commons Protein-Protein Interactions	1.0	null
TE-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.07394
HOOK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67357
KA-81-AG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.4819
ESRRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31086
ZDHHC19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74068
LIME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68582
ACTA2	Pathway Commons Protein-Protein Interactions	1.0	null
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.901113
CSTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15832
Extracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
ISOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62987
CCDC74A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67881
SENP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65743
stratum pyramidale of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03186
ZNF419	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47005
TCF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44107
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12603
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.84185
CLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05811
PNMA6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3393
GRK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58553
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.94149
CE-24-LQ98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.262955
LRRC75A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52331
SPATA33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70486
WDR83OS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94333
ARF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83908
ZNF629	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4542
R3HCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27277
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.975562
MYH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81301
ESYT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59523
MAP3K14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45406
PA-53-BA36_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.301301
DKC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59476
actin filament	GO Cellular Component Annotations 2025	1.0	null
COMMD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87341
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.926841
AA-23-FM46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.02549
CAL 54	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.993616
SLC29A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92973
BHLHA15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1905
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.9142
ING4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66328
PPP6R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50781
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28166
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05834
PMC6961462-NIHMS1544104-supplement-Sup_Tab.xlsx-Sup_Table_3_a-Supplementary_Table_3_Genes_Regulated_by_A_MYB_in_Humans_and_Macaques_Bold_genes_with_reduced_expression_in_Group_3_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
ZDHHC24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43499
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
biological_process	GO Biological Process Annotations 2015	1.0	null
Cells - EBV-transformed lymphocytes	GTEx Tissue Gene Expression Profiles 2023	1.0	1.43434
IA-76-ZU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.392868
testis_7e	HPA Tissue Sample Gene Expression Profiles	1.0	1.39175
OCIAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66366
FZR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22105
Actin/actin-like conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE160817_4_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VPREB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25791
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.926416
MYH9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30811
testis_7d	HPA Tissue Sample Gene Expression Profiles	1.0	1.33513
SHH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52199
KAT6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94019
LRRC58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94224
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15973
496100333_FWM_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.19396
extracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
KMS-28BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.27592
ACSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.16653
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.993616
PMC7438927-Table_2.XLSX-upregulated_in_AA-Upregulated_in_AA_Log2FC_3_Adjusted_P_value_0_01_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12069319-Table1.xlsx-OCAB_p34_BirA-Gene_POU2AF1	Rummagene Transcription Factor Associations 2026	1.0	null
PPIH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89792
CLDN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37138
RELA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.2222
PMC9630632-Table1.XLSX-diff_exp_genes-Group_1_vs_2_AND_Group_2_vs_3_NOT_Group_1_vs_3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
EFCAB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00577
C12orf43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37591
PMC12271601-mmc2.xlsx-OUT_cells_02-Gene_Symbol_TCF23	Rummagene Transcription Factor Associations 2026	1.0	null
nucleus	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.63954
496100497_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.24619
THTPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6788
HCC70	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.17156
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.61565
KATO-III cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.592
MBD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04849
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21049
PPP1R16B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00698
G140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.864768
496100407_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.25248
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.975562
NFKB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.0857
NHLH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52824
MRM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67887
membrane-bounded vesicle	GO Cellular Component Annotations 2015	1.0	null
MZT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3282
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
E2F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2486
TET1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31397
XYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84754
RNF138	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96814
XAB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62171
AARD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65091
intracellular membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
outer plexiform zone in extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08353
intracellular organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
PTTG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30054
MA-06-DJ95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.372265
NCI-H358	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE149901_2_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.984663
TMEM14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77881
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.79399
PDHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9661
GSE236502_2_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
ERI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32111
ZCCHC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50816
HCC2157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.843218
ZFP42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.50094
GNL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86045
HES2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.4274
XD-37-GI34_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.229458
PKN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45833
ZNF140	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.2174
ARRDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.01839
APPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79043
ventral medial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.51415
SCC-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ENDOV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2947
SDCBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11762
CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06746
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.975562
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.98209
MRPL27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95651
IGFBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82788
G-402	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.12337
NEDD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42472
DC-93-NP78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.987286
ASB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63199
SIRT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30091
SP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.826439
CSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25799
IPMK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28509
TTLL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63108
BD-73-TX58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.628814
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
LF-94-HB11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.856295
SMURF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79293
EB1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.2624
BACH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6649
protein kinase binding	GO Molecular Function Annotations 2023	1.0	null
PMC12069319-Table1.xlsx-OCAB_WT_BirA-Gene_POU2AF1	Rummagene Transcription Factor Associations 2026	1.0	null
MLLT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68751
PPP1R15A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33463
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.50524
HL-60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04326
ZNF777	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3612
ED-05-LQ40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.867941
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.17787
496100595_PCx_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.47414
NCI-H2347	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NISCH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48623
UGT3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4249
TMEM145	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.764
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0171
ANXA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.7076
TNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44576
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-26b-5p	MiRTarBase microRNA Targets	1.0	null
WDCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45193
TBC1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49683
laterodorsal part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09373
ELF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76532
stratum radiatum of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.83342
PD-70-VS77_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.857433
NAMALWA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MPV17L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68554
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06158
paraventricular nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32764
HT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.78852
cytoplasmic part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GAS2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02502
Extracellular exosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
E2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4472
PHF20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71529
efo21	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.214
DOR 13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.95818
IGR-37	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.832245
A2780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18911
anatomical structure homeostasis	GO Biological Process Annotations 2015	1.0	null
KF-18-RY71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.86485
KNSTRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87021
vesicle	GO Cellular Component Annotations 2015	1.0	null
HS 578T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02487
CXXC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17286
HN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EGR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	87.4659
PMC8639438-41388_2021_1938_MOESM3_ESM.xlsx-ZNF545-IP_group-Gene_Name_ZFP82	Rummagene Transcription Factor Associations 2026	1.0	null
THOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11508
496100419_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.79418
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10552
OLFML2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54889
Fetal serum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.637
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.14378
TT2609-C02	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2382
496100515_HIP_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.35693
PGK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77099
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06909
STRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60049
ASS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66802
HSD17B10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86083
EOLA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09615
ZNF726	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86165
CYSRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53232
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.59674
TBC1D22B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76893
HBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54714
GRB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63242
XIAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23656
CREB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25598
PFAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94744
SLX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96502
lateral hypothalamic area, tuberal part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.842864
vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.96669
MED28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69324
SNU-423	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.17189
SLC25A3	Pathway Commons Protein-Protein Interactions	1.0	null
RF-48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CNDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36238
ZNF785	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27319
GET3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76524
GSE195559_2_v_7_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TGIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28901
RGL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12382
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33204
PMC11184788-40164_2024_526_MOESM4_ESM.xls-MSC-EV_proteins-Unnamed_4_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
OGT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74179
cervix, uterine	HPA Tissue Protein Expression Profiles	-1.0	-0.779376
FRAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21366
TMEM143	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01567
CORO1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09353
HCT-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.69416
SYCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11375
TM2D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63549
LRP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2312
YBEY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6745
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36933
HIST2H3A	Pathway Commons Protein-Protein Interactions	1.0	null
MEIS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77985
RBMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10183
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.950161
PTPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31049
SLC38A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96081
LC-12-VN85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.08101
B2M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41528
H4/H2A histone acetyltransferase complex	GO Cellular Component Annotations 2025	1.0	null
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.34717
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.92209
TRIM26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29411
PSMD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24113
DD-36-YH76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.24263
EEF1A2	Pathway Commons Protein-Protein Interactions	1.0	null
HIST1H4F	Pathway Commons Protein-Protein Interactions	1.0	null
Histone acetyltransferase complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GC-04-UF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.82265
RPS6KB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21915
NEMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98339
ALDH9A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57535
TGFB1I1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33031
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17278
TTC30A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27043
496100381_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.47341
PEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43654
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.830754
MSX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01919
PMC11749115-loae020_suppl_Supplementary_Table_S2.xlsx-CHOP-high-gene_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
S100A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42539
OLIG3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.814
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.56307
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.06899
RNF103	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03498
IF-31-RN78_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.214868
PLAUR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60212
SPG21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05892
GRHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7035
LTC4S	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11108
OV-90	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC12069319-Table1.xlsx-OCAB_p34_BirA-Gene_Symbol_POU2AF1	Rummagene Transcription Factor Associations 2026	1.0	null
NE-37-JX51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.208185
OLIG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5799
PMC8190596-mmc2.xlsx-RUNX1_mut-RUNX1_mut_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
GATM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54772
496100602_TCx_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.23282
MDST8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ANO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98517
PLEKHA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55012
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.918198
NOL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.9248
CDON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58217
QPRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24094
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6753
H3F3A	Pathway Commons Protein-Protein Interactions	1.0	null
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.910932
FAM222B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43542
GFPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70589
DPYSL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33538
POU3F4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85117
H2AB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58716
SLC12A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6073
pc3	HPA Cell Line Gene Expression Profiles	-1.0	-1.05471
HDHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73941
BC-63-DM76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.41033
MICOS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87128
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06623
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11482
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29789
BARX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39229
NAT14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91323
TCEA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70216
ACOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02836
Golgi apparatus	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.495
G140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.901113
COR-L26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01011
SMARCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82676
CL-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.843436
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28305
SF539	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.50909
PMC11385078-jciinsight-9-172336-s272.xlsx-1DEseq2_Report_AA_BL_vs_EA_BL-Unnamed_1_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
AKT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73399
NALM-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZFP90	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49861
TNPO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66551
CB-16-SY72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.458926
CLOCK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9674
prostate	GTEx Tissue Gene Expression Profiles	1.0	1.70953
BICR 10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.12686
Extracellular space	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
ANTKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47012
PHF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.65157
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24651
SCC90	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DF-75-JD89_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.2571
WE-48-PP43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.281756
pedunculo(pontine) tegmental  nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.897816
ZBTB41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15703
SEMA4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34241
SERP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82434
PMC7825356-8844261.f3.docx-53-TP73_TP73	Rummagene Transcription Factor Associations 2026	1.0	null
MRPS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73279
FF-06-MO73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.6491
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.935791
496100465_HIP_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.51853
CSRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21659
ZNF624	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76894
medial mammillary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.67994
BFTC-909	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.70652
PXMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42246
Brain - Cortex	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.5827
ARTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20042
PMC8649869-EMMM-13-e14351-s012.xlsx-Common_downregulated_elements-264_common_elements_in_siY_T_SRF_DOWN_and_siATF4_SRF_DOWN_SRF	Rummagene Transcription Factor Associations 2026	1.0	null
CENPQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82082
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.843436
TATDN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21266
COX7C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16364
medial superior olive	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2335
GALNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23769
MZ in dorsomedial parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.43691
496100624_PCx_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.48525
SEPTIN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37088
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.28138
UBLCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69685
METTL14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84721
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.9193
GSE238018_1_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
PPM1K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10884
EE-98-PF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.352382
RBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55584
NCI-H1155	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hek293	HPA Cell Line Gene Expression Profiles	-1.0	-1.05471
REL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.1176
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03594
PPP2R5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08814
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.14183
HDAC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54699
PAN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29069
EGR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98549
PIMREG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72641
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30818
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.944868
ANKRD63	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0694
HCE-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NT5C3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.32989
MAN2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89868
PE/CA-PJ15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.830754
GSX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5368
496100357_TCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.26189
TAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01655
ZNF467	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65467
ZNF385B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6281
NCI-H810	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POTEF	Pathway Commons Protein-Protein Interactions	1.0	null
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.975562
WDR82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56877
HCC1500	COSMIC Cell Line Gene Mutation Profiles	1.0	null
testis_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.05598
LA-42-ER00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.294956
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4545
rpmi8226	HPA Cell Line Gene Expression Profiles	1.0	1.09404
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.21967
TMED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6597
MEK2	Kinase Library Serine Threonine Kinome Atlas	1.0	null
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15744
membrane-bounded vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PMC12069319-Table1.xlsx-OCAB_p35_BirA-Gene_Symbol_POU2AF1	Rummagene Transcription Factor Associations 2026	1.0	null
LCORL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23731
GARRE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81802
HC-74-HM63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.30701
HCFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14239
RIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19821
NSUN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02265
KLF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	95.1353
JD-44-KF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.471213
CCRF-SB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13032
daudi	HPA Cell Line Gene Expression Profiles	-1.0	-1.05471
EXOC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68681
ZNF234	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20234
BCOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76832
BMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10384
Extracellular vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
SRSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47866
SOX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59313
NFKBIZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55685
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.975697
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
POU2F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72606
liver	HPA Tissue Protein Expression Profiles	-1.0	-0.779376
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.939255
KA-75-LP02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.234212
GSE195559_6_v_7_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PEX16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55428
MARCHF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1057
NUGC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.993616
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.11
outer SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.931579
HCC1569	COSMIC Cell Line Gene Mutation Profiles	1.0	null
VPS33A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31214
granular layer of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.60204
TTLL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10914
CHTF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76378
OSGEP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43253
HMGB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.943
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
H4C8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99858
ZZZ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78927
AE-85-KE62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.718361
ERAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47215
B-50 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.843
DAZAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73148
GRHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7384
RFX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05043
ELP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96832
OAW28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.876603
neuron projection	GO Cellular Component Annotations 2025	1.0	null
nerve	GTEx Tissue Gene Expression Profiles	-1.0	-1.42504
GSE166783_0_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF75A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87774
VHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70521
PAFAH1B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82857
axon	GO Cellular Component Annotations 2025	1.0	null
C21orf91	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.399
PLAU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80031
NBPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9475
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.903643
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.25971
Synapse	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
CD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67569
HEY1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.1114
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
NHLRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20928
UBE3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27857
RBM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13269
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.858778
JUN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43524
membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
TMEM203	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21948
SLC38A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31017
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.926416
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.841733
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.11345
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0171
ZBTB14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.6299
endopiriform nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17066
RTCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04474
AF-99-HA02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.755458
TECPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14346
E2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5965
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6884
CB-16-SY72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.13784
NVT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.112
RTCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90048
OTOL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34533
CELSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58066
SKOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22509
MEIOSIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.96742
H3F3C	Pathway Commons Protein-Protein Interactions	1.0	null
agranular insular cortex (area Iag)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03297
Supramolecular polymer	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
496100373_PCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.69286
MOLT-16	COSMIC Cell Line Gene Mutation Profiles	1.0	null
extracellular vesicle	GO Cellular Component Annotations 2015	1.0	null
GSE238018_1_v_0_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
DRGX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42145
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.11453
ASK1	Kinase Library Serine Threonine Kinome Atlas	1.0	null
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.993616
ZNF665	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58943
BCLAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91938
CCF-STTG1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
inner CP in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.98403
HEP_3B2_1-7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
YARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09631
PER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74267
ZD-18-MI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.59403
MSH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20958
FKTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2239
SLC10A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36501
HDAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11418
C11orf98	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.32548
PEX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60337
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38707
LA-42-ER00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.237425
DA-33-BM26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.683866
MECOM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28401
GSC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95975
RAD23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77434
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.975562
TOMM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13284
ARPC1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42862
PMC12069319-Table1.xlsx-OCAB_WT_BirA-Gene_Symbol_POU2AF1	Rummagene Transcription Factor Associations 2026	1.0	null
NIPAL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86076
SA-32-CC58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.211981
organelle	GO Cellular Component Annotations 2015	1.0	null
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.56617
TIMM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15935
NDUFS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91066
NOL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5004
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03594
SHP-77	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SMARCE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40559
EEF1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26535
496100389_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.61422
MPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40427
ABHD14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49069
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21049
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
SUN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00193
S100A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77469
ACVR2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8226
NuA4 histone acetyltransferase complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
ARL5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10822
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.830754
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04824
H2BC15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07314
skeletal muscle	HPA Tissue Gene Expression Profiles	1.0	1.18426
SIRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92685
TMEM219	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64757
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1426
CHSA0011	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNW1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33929
NDUFV2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73625
Neuron projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
LAMC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21161
KCTD21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57171
lateral reticular nucleus (principal part)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.6641
PMC12069319-Table1.xlsx-OCAB_p40_BirA-Gene_POU2AF1	Rummagene Transcription Factor Associations 2026	1.0	null
PSMD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11357
MHH-PREB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.29195
PMC7438927-Table_2.XLSX-upregulated_in_AA-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
FOXJ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.82081
RXYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68812
STAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67922
DROSHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90776
RALGPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61236
Endometriosis of uterus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.299
MOLP-8	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	3.47922
LMBRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87378
oral mucosa	HPA Tissue Protein Expression Profiles	-1.0	-0.779376
Extracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
caco2	HPA Cell Line Gene Expression Profiles	1.0	0.9075
BLM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23343
tissue homeostasis	GO Biological Process Annotations 2015	1.0	null
KEAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08859
EEF1A1P5	Pathway Commons Protein-Protein Interactions	1.0	null
SHARPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44693
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03172
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04071
BA-56-QV45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	4.19654
PMC12289921-41467_2025_62099_MOESM4_ESM.xlsx-MI-2-80-Gene_Symbol_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
cell morphogenesis involved in neuron differentiation	GO Biological Process Annotations 2025	1.0	null
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.6077
outer SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.62168
496100519_HIP_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.0335
DHRS7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07775
MPZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65865
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21049
vagina	HPA Tissue Protein Expression Profiles	-1.0	-0.779376
mc2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.656
FAM133B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71279
WWC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04197
hippocampus	HPA Tissue Protein Expression Profiles	-1.0	-0.779376
SIRT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1998
PRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45699
SSR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39625
CI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.59841
BE-42-IC00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.29916
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19685
BB-77-QQ71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.42643
SUPT16H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83132
PRKCSH	Pathway Commons Protein-Protein Interactions	1.0	null
PPM1F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76344
PGRMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44549
PPP1R14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40315
ANLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58428
GMS-10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
head of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.892205
ZBTB43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74757
PICK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77277
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.04839
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.853894
CD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.946
MIEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47115
DLX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1707
NuA4 histone acetyltransferase complex	GO Cellular Component Annotations 2023	1.0	null
AOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8909
SMIM29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78767
KEAP1	Pathway Commons Protein-Protein Interactions	1.0	null
internal segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1302
NCI-H835	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0288
DD-75-HY40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.04806
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.09153
MANF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4421
BLTP3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42693
extracellular space	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
SPRED3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41332
NAA40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.71521
S0-EE-YEKU_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.406192
H4/H2A histone acetyltransferase complex	GO Cellular Component Annotations 2023	1.0	null
SYT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9831
HS 895.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.93146
ACCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44391
TFDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83432
KMS-28BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.64493
WHRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99069
MEX3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74251
DDIAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06449
CHAGO-K-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.853894
SK23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.10234
SW 982	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.849782
EC-62-OE64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.37381
ATP1A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05511
SDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79693
CETN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.77732
AC-84-QG99_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.784891
PGM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84443
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12734
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GC-04-UF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.377929
NCI-H2029	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RNF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28894
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.80376
ADO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50603
COL8A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47628
ZNF212	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.75776
IRF2BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4221
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.19217
ISG15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9801
ARFGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4014
stratum lacunosum-moleculare of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.849946
kinase binding	GO Molecular Function Annotations 2023	1.0	null
TP73	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7397
C6orf136	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29831
NUP54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37704