association	dataset	threshold value	standardized value
ATIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56334
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9932
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5159
HCL-V	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.663
Hereditary spastic paraplegia 76	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.483
RNF130	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19453
ZNF862	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.118
Lymphoid tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.025
METTL23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93219
DLG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88401
FJX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3347
GSE221742,GSE221743_1_v_2_sipa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
DD-75-HY40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.384812
GSE221742,GSE221743_1_v_0_sipa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HMGXB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66907
GSE172016_2_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
RAB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92351
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZNF524	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08161
Phagocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.322
PLEKHF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87806
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5164
UGT3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4249
GSE119978,GSE180930_6_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF708	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.7114
RWDD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45785
NCOA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5654
496100385_TCx_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.98961
NPHP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.442
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.318063
CSRNP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99177
496100453_HIP_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.13082
GSE213228_2_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4819
ZFP82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71395
GSE133516_5_v_6_kat7_human	RummaGEO Gene Perturbation Signatures	1.0	null
SHISAL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47973
H4C5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.57907
TCEAL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51415
GSE148657_2_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
B-lymphoblast	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.025
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1453
Mononuclear phagocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.322
ANKRD30A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35754
S0-EE-YAXR_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.34667
Urinary system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7148
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.735
C-fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.86
GSE76425_0_v_12_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SEZ6L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28474
Intrinsic component of synaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.243
ADCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63871
AB-23-UX23_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.366977
PCDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77052
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8354
496100454_FWM_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.47358
Synovial sarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.785
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1657
TOR4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69423
BE-81-QL64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.32087
OGFRL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61361
SPHK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99853
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6779
AK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20108
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MEIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0546
IFITM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6632
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.0571
MGA::EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4341
RBM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13269
GSE233679_6_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8965
ZFP30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12362
GSE162892_3_v_5_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.1177
SDHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17371
GSE206729_3_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZBTB32	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3996
Oligospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.369
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2119
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Cotton fibre	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.891
ID-12-NA84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.363101
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.2822
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5714
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8931
ANKRD49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84696
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5988
PHF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69601
PMC11615365-41467_2024_54246_MOESM5_ESM.xlsx-RT112-Numb-KD_vs_Ctr-KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CREB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8314
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.3612
FSTL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08894
GATAD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65653
ZNF770	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52011
TMCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09184
MRPL38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43855
TBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94722
MFAP3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82568
PMC10861538-41467_2024_45669_MOESM7_ESM.xlsx-Sheet1-Supplementary_Data_4_DEGs_upon_KD_of_EVT_TFs_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1052
Lymphoid cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.025
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4087
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Exotropia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.342
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8397
Hematopoietic cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.322
ZNF547	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5172
BE-45-UU35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.341638
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6317
GSE220806_1_v_3_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100630_PCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.44124
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.049
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6446
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.401
Astrocyte projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.646
PMC10625120-ADVS-10-2304638-s002.xlsx-Table_S6-Table_S5_The_RNA-seq_of_KLF5_in_OVCA420_cells_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4504
SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6655
USF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6206
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.113
WTIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56599
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7573
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2104
Choanomastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.703
496100565_FWM_probable Alzheimer's disease_TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.74543
GSE108084_3_v_2_epinephrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Joubert syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.131
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE221327_1_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119978,GSE180930_0_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100634_HIP_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.90137
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Timothy syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.361
Strabismus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
ATF7IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81306
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.25901
UD-20-ER54_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.211996
GSE238018_3_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FA-43-XS35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.312113
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
DASH complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.583
FOXP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4657
SH2B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82362
Carpal tunnel syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.273
Diabetic neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.278
TTLL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71007
Forearm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.484
TFEB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5964
GSE167956_1_v_0_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE227592_13_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE235066_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
myoclonic-atonic epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.223
LAG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88305
Aortic valve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.906
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.53647
Calpain complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.595
GSE206729_2_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55349
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.915
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-HL-60-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_HL-60_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
SUCO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82469
496100402_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.241
PMC11615365-41467_2024_54246_MOESM5_ESM.xlsx-RT112-Numb-KD_vs_Ctr-KD-ensemblGeneId_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ABCG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51013
EBNA1BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64546
KLF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02344
ACO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37575
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3893
GSE85880,GSE85881_0_v_1_tretinoin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.602
FHL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63592
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.077
TLNRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28686
GSE128333_2_v_5_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6221
RSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24679
SCAPER	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34021
Tentacle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.675
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4094
NAPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03538
ARC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.565
TEF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9703
ZNF524	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5625
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	12.97
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.01
Nicolaides-Baraitser syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.001
PDHX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02395
Leukocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.322
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-Kasumi-1-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_Kasumi-1_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
FOSB::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9985
UNC119	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05018
STARD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61864
RIC8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88613
CFAP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65209
496100353_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.56015
GSE249098_3_v_0_mthfd1l_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67064
ETV5::HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6792
496100431_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.52818
GSE238018_3_v_2_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DCXR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48923
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8968
SMIM10L2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78086
GSE119978,GSE180930_2_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PGR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65799
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7135
Helper T-lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.019
ESR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.0853
RRP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32243
KMT5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38019
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6049
GSE140646_0_v_1_atf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AGBL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25004
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8827
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0856
Hairy cell leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.071
GSE262134_0_v_1_dnajc12_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE76425_0_v_5_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE201668_0_v_1_ncor2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Spinothalamic tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.864
GSE264621_1_v_3_secretin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158320,GSE183351_0_v_3_lin28b_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100346_FWM_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02915
GSE221327_1_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Transcription factor TFIIA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.759
STARD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11811
GSE206729_5_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RAB1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37325
TTLL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47942
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4501
STAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16191
RNASEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75488
FTO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49873
B-lymphoblastoid cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.025
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.7757
QRICH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27235
FOXB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49058
CYB5RL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39249
SOX13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8271
TBX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35593
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2444
496100333_FWM_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.42085
UTP18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32623
496100608_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.40294
TXNDC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41144
EARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00867
Urinary tract	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZSCAN32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8728
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5549
496100532_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.40522
ZNF470	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44205
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8214
PLPPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79447
GSE151412_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6813882-NIHMS1526297-supplement-2.pdf-18-KLF6_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Pars reticulata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.621
CASKIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29922
ZBTB44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83191
GSE172458_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
T-lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.019
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE118816_2_v_3_myo1c_human	RummaGEO Gene Perturbation Signatures	1.0	null
pi1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.667
BHLHE40	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1419
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3636
TASOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39955
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8827
CREB3L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86677
GSE111247_0_v_7_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.296
Immune system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.025
KIF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91674
ZNF282	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5821
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1047
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
C1orf115	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76829
GSE165678_0_v_5_stat5a_human	RummaGEO Gene Perturbation Signatures	1.0	null
LZTS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83518
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Armfield syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.751
Abductor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.796
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4658
NRL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6237
496100564_TCx_no dementia_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.5596
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2826
PRKX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28497
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Excretory gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
496100495_FWM_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.24101
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4138
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2019
Marrow cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.322
NFKBID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94591
GSE238018_3_v_0_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Dermatome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.638
AMZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23319
SPZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2995
GTEx Prostate 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-4.14344
Blood	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.401
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1939
Keloid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.036
PSAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25865
Hematopoietic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.401
PLEKHG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06449
NCI-H292 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.625
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.02821
Mononuclear cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.322
ZNF322	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42377
SCAF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29522
GSE235066_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SOX10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6418
ATP5IF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95225
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6609
MNX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5848
GSE227592_6_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Nerve compression syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.236
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9759
Formate dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.685
ZB-16-BR73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.373279
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8258
TFEC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4951
GSE145171_0_v_1_prox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
C22orf23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73006
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.834
GSE160817_3_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Mlg	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.553
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4961
GFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94978
SRI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41522
Joubert syndrome 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.752
FMNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91399
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0683
SPRED3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31735
GSE165636_0_v_4_tofacitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100623_PCx_no dementia_TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.39663
ZNF628	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40601
ATF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1168
SLC30A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04316
NCOA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8971
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.2912
RXRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.278
Nephronophthisis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.69
FAAP24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90451
ZNF487	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65937
ATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3184
FASTKD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76406
NEK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69767
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04278
SERINC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82646
DBP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.504
Perineurium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.581
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9966
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.401
GSE248659_1_v_0_klf5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.025
DF-93-BT88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.549852
RB1CC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86846
CC-61-HH09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.992262
THOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11415
HASPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68982
Monocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.322
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.53431
GSE119978,GSE180930_3_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S2.xlsx-S2B_in_vivo_shared-Suppl_Table_S2B_shared_genes_between_RCAS-YAP1-MAMLD1-dR3R1_RCAS-YAP1-FAM118B_RCAS-YAP1-TFE3_in_vivo_tumors_RCAS_mouse_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
PFKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27299
GSE190384,GSE190386_0_v_8_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Zona incerta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.723
GSE157036,GSE166411_3_v_1_halofuginone_human	RummaGEO Drug Perturbation Signatures	1.0	null
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9756
Lymphoblast	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.025
TYW3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89997
PMC12775252-18_2025_5991_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_2_Up-_and_down-regulated_genes_in_TCF7L2-depleted_EVT_compared_to_control_EVT_TCF7L2	Rummagene Transcription Factor Associations 2026	1.0	null
SCG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67403
Labyrinthine zone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.589
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8478
GTF2F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2033
GSE82032_3_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE137325_3_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brachydactyly type D	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.048
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8315
HIF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74489
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.26117
GSE169152_5_v_7_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6528