association dataset threshold value standardized value TP63-23658742-EP156T-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GSE123836_1_v_0_myf6_mouse RummaGEO Gene Perturbation Signatures 1.0 null RARA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.83112 Piriform-amygdalar area, pyramidal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.67845 RHJT DepMap CRISPR Gene Dependency 1.0 3.40148 GTEX-XUJ4-2526-SM-4BOO4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 cingulate gyrus, parietal part, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.8284 GTEX-XMK1-2626-SM-4B65R GTEx Tissue Sample Gene Expression Profiles 1.0 0.971041 HDQ-P1 COSMIC Cell Line Gene CNV Profiles -1.0 -3.24687 PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Nearest_Ensembl_HNF4A Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_WI38_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null GTEX-TMZS-0326-SM-3DB9P GTEx Tissue Sample Gene Expression Profiles 1.0 1.16752 Lung adenocarcinoma_LUAD_TCGA-78-8660-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posteroventral (inferior) parietal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.941146 Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null MAN2B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45807 MAX ENCODE Transcription Factor Targets 1.0 null Perturb_18382_KO_Izumo1r_SRP354764 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.8023 HOXB4_induction_GDS3036_138_mouse_ES cell-derived embryoid bodies (EBs) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null ORAI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58996 H3K4me3_Panc1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null RFX5 ENCODE Transcription Factor Targets 1.0 null CPS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00659 HMGB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59602 MDA-MB-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.12939 HCC2218 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.922359 PBX3_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SUM 149PT Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.4774 POU2F2 ENCODE Transcription Factor Targets 1.0 null DANG CCLE Cell Line Gene CNV Profiles -1.0 -1.37423 GTEX-XUJ4-1426-SM-4BONT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 STOX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60371 MANF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4421 YIPF5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44068 GSE195559_0_v_5_notch1_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-X261-3226-SM-3NMC3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.916641 PARP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23991 CUX1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SMAD9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32051 FOSL2::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.4871 ZNF783 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46874 GTEX-R55C-0005-SM-3GAE9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 hsa-miR-663 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 spleen HPA Tissue Protein Expression Profiles -1.0 -1.51613 anterior pretectal nucleus, ventral superficial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.68359 POLR2A_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XUYS-0326-SM-47JX2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.22111 SREBF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 53.9646 CoPV part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43401 BRF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23497 RAB9A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.69167 CREB1 ChEA Transcription Factor Targets 1.0 null MOLM13 DepMap CRISPR Gene Dependency 1.0 3.07456 COLO680N CCLE Cell Line Gene CNV Profiles -1.0 -1.37158 CHD2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PLZ5-0426-SM-3P612 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-NPJ8-0007-SM-2D7VX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-XLM4-0011-R10A-SM-4AT5P GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 MAX_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null E2F6_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QLQW-0426-SM-447A7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 CEBPB_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZSCAN31 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30356 GTEX-S3XE-2026-SM-3K2B5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.1231 HDAC2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ATF3_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TP53INP2_OE_GDS5054_387_mouse_muscle GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null SIN3A_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null ELK1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GNG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.64186 negative regulation of cellular process GO Biological Process Annotations 2015 1.0 null sublayer 6b of OCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3844 ESR1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 54.7111 USF1_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_lung_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAL1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYBL2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAJI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.887445 XIAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.23656 CREB1_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5971-01A-11R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CDCA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2292 ATP1A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05511 OC-314 COSMIC Cell Line Gene Mutation Profiles 1.0 null HCFC1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-Q2AH-0326-SM-48U1K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 PMC8390401-12094_2021_2621_MOESM2_ESM.xls-S7-Supplemental_Table_S7_Genes_that_are_commonly_upregulated_in_both_pY-STAT3_Low_groups_v_pY-STAT3_High_groups_STAT3 Rummagene Transcription Factor Associations 2026 1.0 null ASCC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66053 phosphatase binding GO Molecular Function Annotations 2025 1.0 null H3K4me3_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RCOR1 ENCODE Transcription Factor Targets 1.0 null BCL3_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null REST_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE135350_3_v_0_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null Gastrointestinal tract TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 CCNT2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE174498,GSE174500_0_v_8_asparaginase_human RummaGEO Drug Perturbation Signatures 1.0 null posterior triangular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.7287 BHLHE40_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE152441,GSE152442_7_v_5_folic acid_human RummaGEO Drug Perturbation Signatures 1.0 null MAZ_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me2_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H413 DepMap CRISPR Gene Dependency 1.0 2.36748 GTEX-PSDG-0426-SM-2S1OF GTEx Tissue Sample Gene Expression Profiles 1.0 1.07488 lateral habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.22955 rostral ventrolateral reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44858 SUN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00193 SMPDL3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8931 APP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63123 GTEX-XV7Q-2426-SM-4BRV8 GTEx Tissue Sample Gene Expression Profiles 1.0 0.996392 enzyme regulator activity GO Molecular Function Annotations 2015 1.0 null ESR1 JASPAR Predicted Transcription Factor Targets 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7097-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_14651_KD_Dis3_SRP297013 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.71208 GTEX-W5WG-1526-SM-4LMIG GTEx Tissue Sample Gene Expression Profiles 1.0 0.946387 COLO-783 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.03332 periaqueductal gray substance, dorsolateral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.84389 HIVEP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93835 SIK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02479 LIN28A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60968 ACBD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13581 GTEX-RU72-0011-R9A-SM-2TF67 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-S95S-1126-SM-4B64E GTEx Tissue Sample Gene Expression Profiles 1.0 0.894427 496100376_FWM_probable Alzheimer's disease_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.56395 VZ in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.837085 GTEX-WL46-0626-SM-3LK7R GTEx Tissue Sample Gene Expression Profiles 1.0 1.54691 CRTC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.60389 GTEX-Q2AH-0426-SM-2I3EP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 ZNF263 ENCODE Transcription Factor Targets 1.0 null POLR2AphosphoS2_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TYW3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.89997 GM2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11516 HPAFII DepMap CRISPR Gene Dependency 1.0 4.3912 Prdm14 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.4944 KDM5B_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null COLO679 CCLE Cell Line Gene CNV Profiles 1.0 1.54542 GSE133329_0_v_3_trim28_human RummaGEO Gene Perturbation Signatures 1.0 null GSE160083,GSE160084_1_v_3_tamoxifen_mouse RummaGEO Drug Perturbation Signatures 1.0 null H3K4me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of villous mesenchyme_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-548j TargetScan Predicted Conserved microRNA Targets 1.0 0.766596 BCL2L11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04321 PL-21 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.69369 PMC3419980-leu201249x4.xls-All_expression_genes_RUNX1ETO-All_differentially_expressed_genes_with_more_than_2_fold_in_at_least_one_day_set_and_correlate_with_RUNX1_ETO_peaks_genes_RUNX1 Rummagene Transcription Factor Associations 2026 1.0 null H3K36me3_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QVJO-0008-SM-447AU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 H3K4me1_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-7304-02A-12R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IRF1 ENCODE Transcription Factor Targets 1.0 null RGP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83904 intermediate part of r7B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.64777 Brain Lower Grade Glioma_LGG_TCGA-DU-A5TR-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LYPD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.63665 amygdalostriatal transition area Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.900618 Primary somatosensory area, lower limb, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0313 GTEX-X4EO-0006-SM-3P5ZF GTEx Tissue Sample Gene Expression Profiles 1.0 0.972517 ASL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55131 H3K4me3_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-S33H-1226-SM-4AD69 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 MUS81 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.13617 POLR2AphosphoS5_HL-60_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3466-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DPF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03948 MRE11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.95178 H3K4me3_fibroblast of gingiva_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null negative regulation of molecular function GO Biological Process Annotations 2015 1.0 null ESYT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59523 H3K27ac_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null TCF3 ENCODE Transcription Factor Targets 1.0 null primary motor cortex (area M1, area 4)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.44745 ATF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null CEBPB_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TFE3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.6975 GATA2_G1E-ER4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-TSE9-3126-SM-4DXSY GTEx Tissue Sample Gene Expression Profiles 1.0 0.916116 COV504 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.20036 DHX35 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67497 r7 basal plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25671 GTEX-PLZ4-1326-SM-2S1O7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GSE178227_1_v_0_tet1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-R55E-0526-SM-2TC6B GTEx Tissue Sample Gene Expression Profiles 1.0 1.29571 POLR2A_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null striatum_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.31507 ATF3 ENCODE Transcription Factor Targets 1.0 null SU-DHL-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.0157 FOXP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90057 GTEX-SUCS-0626-SM-32PM5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 PA-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.44886 USF1_A549_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null Superior colliculus, motor related, intermediate gray layer, sublayer b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08278 MRPL30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.48926 JUND_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WRHU-0826-SM-3MJFN GTEx Tissue Sample Gene Expression Profiles 1.0 1.11311 Rxra JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 36.0971 GSE164874_5_v_10_prednisolone_human RummaGEO Drug Perturbation Signatures 1.0 null THOC5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59575 H3K9ac_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ZKSCAN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20907 ventral paracommissural tectal nucleus, m1 part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.34979 H3K4me3_fibroblast of gingiva_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null MYC_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOS ENCODE Transcription Factor Targets 1.0 null GTEX-P4QT-1626-SM-2S1NP GTEx Tissue Sample Gene Expression Profiles 1.0 1.27237 DNM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.95115 STAT3_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF75D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74617 H3K4me3_GM12864_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null JUN ENCODE Transcription Factor Targets 1.0 null GTEX-QMRM-1726-SM-2S1QG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 BCKDHA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41875 PMC9894241-pnas.2211429119.sd05.xlsx-G1_REST-Dataset_S5_Differentially_expressed_genes_in_G1-G8_REST Rummagene Transcription Factor Associations 2026 1.0 null NACC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56753 pallidohypothalamic nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.13198 GTEX-W5WG-1926-SM-4KKZK GTEx Tissue Sample Gene Expression Profiles 1.0 1.15326 RUNX3 ENCODE Transcription Factor Targets 1.0 null F12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.67726 ATP5IF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91593 ZNF747 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0199 caudal portion of VFC (area 44) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.941036 basal ventral medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.845151 H3K4me3_choroid plexus epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Leukemia, Adult T Cell_Blood monocyte_GSE10789 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.01388 regulation of metabolic process GO Biological Process Annotations 2015 1.0 null KDM5B ENCODE Transcription Factor Targets 1.0 null submedius thalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18999 Lung squamous cell carcinoma_LUSC_TCGA-51-4081-01A-01R-1100-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SIX5 ENCODE Transcription Factor Targets 1.0 null PITPNM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06417 TCCSUP CCLE Cell Line Gene Expression Profiles -1.0 -2.47937 amygdalohippocampal area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11306 CREB1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZMAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05073 YY1 MotifMap Predicted Transcription Factor Targets 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-A4BX-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A ENCODE Transcription Factor Targets 1.0 null GTEX-T6MN-0726-SM-32PML GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 MYBL2_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GATA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08335 GTEX-U4B1-1726-SM-3DB9F GTEx Tissue Sample Gene Expression Profiles 1.0 0.825411 ZNF225 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39023 GTEX-S95S-1426-SM-2XCDM GTEx Tissue Sample Gene Expression Profiles 1.0 2.06011 cerebellar vermis Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.906985 IMR32 CCLE Cell Line Gene CNV Profiles 1.0 1.75701 HNF4A_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SN8G-0326-SM-32PLG GTEx Tissue Sample Gene Expression Profiles 1.0 1.26802 MYF5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94761 NB17 DepMap CRISPR Gene Dependency 1.0 3.64487 KCNK5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87224 H3K4me1_mononuclear cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-UTHO-3026-SM-3GAFB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A40U-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null E2F1 ENCODE Transcription Factor Targets 1.0 null GSE174701_4_v_7_maml3_human RummaGEO Gene Perturbation Signatures -1.0 null LTBR_INHIBITION - 27 Day_GDS2005_731_mouse_Lymph nodes (MG-430B) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null DIXDC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55205 TCF12_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100369_PCx_no dementia_TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.29072 H3K4me3_GM06990_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CAL33 CCLE Cell Line Gene Expression Profiles -1.0 -2.92918 NR1H3 ChEA Transcription Factor Targets 1.0 null ELF1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PINLYP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70784 GTEX-XOTO-2926-SM-4B65G GTEx Tissue Sample Gene Expression Profiles 1.0 0.836472 H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC13187244-41392_2026_2766_MOESM2_ESM.xlsx-Table_S17-Table_S17_Differentially_expressed_genes_in_OCI-AML3_cells_ZMIZ1_inhibitor_SIH-001_4E_vs_DMSO_RUNX2 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me1_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-T6MN-2726-SM-4DM77 GTEx Tissue Sample Gene Expression Profiles 1.0 0.975191 CTDSP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39836 XRCC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12926 CREB1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Dorsal part of the lateral geniculate complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01852 YIF1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.98854 FAM136A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19352 MAP3K12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62414 Cortical amygdalar area, posterior part, lateral zone, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09739 BICRAL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.27205 ATF3_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAF1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CREB1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNU349 CCLE Cell Line Gene Expression Profiles -1.0 -2.13264 H3K4me3_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null TFEB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.6306 PMC9360325-DataSheet_3.xlsx-DEGs_DLPSvsMLPS_71UP-Data_file_S3C_Upregulated_DEGs_in_DCATH-2_trained_LPS-stimulated_dTHP-1_cells_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-T5JW-1126-SM-4DM5V GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-XGQ4-1626-SM-4AT6J GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 SLC6A9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84205 PMC12575911-43556_2025_329_MOESM2_ESM.xlsx-SD2_MITF_CoBindingGenes-Gene_MITF Rummagene Transcription Factor Associations 2026 1.0 null skeletal muscle TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 trochlear nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.13894 DMS 273 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.36432 GTEX-SE5C-1526-SM-4BRWU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 MZ in dorsomedial parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.61062 Lung adenocarcinoma_LUAD_TCGA-NJ-A4YF-01A-12R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2AphosphoS5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29R-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ELF1_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KAT2A ENCODE Transcription Factor Targets 1.0 null H3K4me3_cardiac mesoderm_hg19_8 ENCODE Histone Modification Site Profiles 1.0 null REST_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_erythroblast_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null C7orf50 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54262 GOLGA6L4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68182 inferior occipital gyrus, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.04546 GTEX-WFG8-2426-SM-3GILL GTEx Tissue Sample Gene Expression Profiles 1.0 1.20689 Primary somatosensory area, lower limb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15907 NCI-H1355 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.51538 ATP2B4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55269 primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.32638 HCT8 CCLE Cell Line Gene Expression Profiles -1.0 -2.35539 Hair follicle bulge stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.651 H3K27ac_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE166783_3_v_2_tp53_human RummaGEO Gene Perturbation Signatures -1.0 null TEAD1 JASPAR Predicted Transcription Factor Targets 1.0 null POLR2A_bone marrow macrophage_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RGS14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.97119 AMPD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55921 cytoplasmic part LOCATE Predicted Protein Localization Annotations 1.0 null GABPA_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ACADSB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15865 H3K4me3_HCT116_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-P5-A5EU-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-T6MN-0526-SM-32PMS GTEx Tissue Sample Gene Expression Profiles 1.0 1.18347 NCI-H1915 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.84559 ZNF677 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46827 superficial stratum of r4BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.91649 NRAS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01107 MTERF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.22479 BHLHE40_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null AML193 CCLE Cell Line Gene Expression Profiles 1.0 1.60923 GSE182680,GSE182683_0_v_13_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null POLR2A_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null OB granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13331 HCC1576 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.934554 FOXA2-19822575-HepG2-human ChEA Transcription Factor Binding Site Profiles 1.0 null NCLN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22194 Medial geniculate complex, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.05791 MAX_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RRM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13684 H3K4me3_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PML_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null tretinoin_homo sapiens_gpl6244_gds4180 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null CEBPB_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CA12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9781 SLC27A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8402 amygdaloid complex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.61504 superficial stratum of PcPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.68379 HNF4A-19822575-HepG2-human ChEA Transcription Factor Binding Site Profiles 1.0 null H3K4me3_cardiac fibroblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null negative regulation of biological process GO Biological Process Annotations 2015 1.0 null H3K4me3_fibroblast of villous mesenchyme_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null EGR1 ChEA Transcription Factor Targets 1.0 null WERIRB1 DepMap CRISPR Gene Dependency 1.0 2.21069 FADU DepMap CRISPR Gene Dependency 1.0 5.49202 GTEX-RM2N-0626-SM-48FD6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 Perturb_13480_KO_Bmal1_SRP260650 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 8.12772 GTEX-QV31-1426-SM-2S1QD GTEx Tissue Sample Gene Expression Profiles 1.0 1.06411 GTEX-XYKS-2426-SM-4AT43 GTEx Tissue Sample Gene Expression Profiles 1.0 1.55391 LUZP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61949 POLR2A_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GATA2 ENCODE Transcription Factor Targets 1.0 null GTEX-U412-0006-SM-3DB8J GTEx Tissue Sample Gene Expression Profiles 1.0 0.9301 FLII CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41768 GTEX-T5JW-1526-SM-4DM5E GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 PRCP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08832 POLR1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7009 ACOT9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40562 parvicellular interstitial nucleus of the posterior commissure Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.01287 Ventral pallidus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.96404 Lung adenocarcinoma_LUAD_TCGA-73-7499-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1937 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.24044 HN CCLE Cell Line Gene CNV Profiles -1.0 -1.45672 POLR2AphosphoS5_U-87 MG_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE140715,GSE140716_0_v_1_metformin_mouse RummaGEO Drug Perturbation Signatures 1.0 null GTEX-PLZ6-1526-SM-2S1OC GTEx Tissue Sample Gene Expression Profiles 1.0 1.16565 GABPA_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary auditory cortex (core)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.88188 ventrolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.14959 GTEX-R55C-1726-SM-3GADJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.11753 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70U-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27ac_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null mitochondrion LOCATE Predicted Protein Localization Annotations 1.0 null GSE183327,GSE183328_1_v_0_ddit3_human RummaGEO Gene Perturbation Signatures 1.0 null CLIP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96647 Cochlear nucleus, subpedunclular granular region Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.52601 H3K4me3_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null FYN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25731 MEL-HO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.55728 GTEX-UJHI-1726-SM-3DB9B GTEx Tissue Sample Gene Expression Profiles 1.0 1.38599 GTEX-T5JW-2026-SM-4DM63 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 H3K4me3_fibroblast of pulmonary artery_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null SUZ12 ChEA Transcription Factor Targets 1.0 null H3K27ac_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null chr17_81853470_A_G_b38 GTEx eQTL 2025 1.0 1.55468 MZ in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.05615 SW1271 COSMIC Cell Line Gene Mutation Profiles 1.0 null mRNA_SOX9_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Retrosplenial area, ventral part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24214 RUNX3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XOT4-0005-SM-4B64S GTEx Tissue Sample Gene Expression Profiles 1.0 0.915644 TRAM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69222 H3K79me2_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HNF4G CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43707 AVPI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80393 EP300_T47D_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ACTL10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49671 KLF13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10532 pancreas HPA Tissue Protein Expression Profiles -1.0 -0.738732 SP in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.93591 SNU-387 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.929589 GSE125862_2_v_0_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null MAZ_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hl60 HPA Cell Line Gene Expression Profiles 1.0 1.67216 KANK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.07627 TLE2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33306 DLX6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9164 superior occipital gyrus, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.09998 GTEX-QEG5-1126-SM-33HC2 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-P44H-2426-SM-2XCEJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-N7MT-0011-R7a-SM-2I3FZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 H3K4me3_SK-N-MC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ZNF263_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAF::NFE2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.789 POLR2AphosphoS5_SK-N-MC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_H7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null precommissural nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.66526 GTEX-X8HC-0726-SM-46MWG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 MECR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30218 RCOR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-V955-1926-SM-4KL1L GTEx Tissue Sample Gene Expression Profiles 1.0 0.829026 XRCC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31217 PRPS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05201 GTEX-XPVG-2626-SM-4B669 GTEx Tissue Sample Gene Expression Profiles 1.0 0.946032 TCFAP2C-20176728-TROPHOBLAST STEM CELLS-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null USF2_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XUJ4-0726-SM-4BOOP GTEx Tissue Sample Gene Expression Profiles 1.0 0.987984 PKIG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83658 mantle zone of r7BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02209 GTEX-XQ8I-0626-SM-4BOPT GTEx Tissue Sample Gene Expression Profiles 1.0 2.56299 PML_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QLQW-0726-SM-447AA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 Primary somatosensory area, barrel field, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00736 PYCR3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1783 TCF12_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K79me2_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-CC-A1HT-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-1908 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 H3K36me3_NT2-D1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mRNA_SOX2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null RFX5_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QEG4-0626-SM-2S1OY GTEx Tissue Sample Gene Expression Profiles 1.0 1.52772 POLR2A_endothelial cell of umbilical vein_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null SIN3A ENCODE Transcription Factor Targets 1.0 null GSE174701_4_v_3_maml3_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-SUCS-0006-SM-4DM59 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 H3K9ac_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null spinal (inferior) vestibular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.876664 GTEX-OHPM-1626-SM-2HMK4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.13639 CTCF_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null ASCL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43215 Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MU-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TP63 ChEA Transcription Factor Targets 1.0 null RV16_0Hour-B2B_None_GSE28904 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.75047 H3K4me3_retinal pigment epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null septopallidal shell area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0635 central part of CEl Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.38968 GTEX-WHSE-3126-SM-3P5ZI GTEx Tissue Sample Gene Expression Profiles 1.0 0.959304 MYL12B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17776 GTEX-SIU7-1426-SM-4BRWT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 POLR2A_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-UPK5-1126-SM-3GAEJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-R55C-0008-SM-48FCF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 EP300_GM12878_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null CREB1 ENCODE Transcription Factor Targets 1.0 null NCI-H2023 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.959417 TARBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57594 H2AFZ_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Geniculate group, dorsal thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.63435 ESRRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.8031 SP4_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHD2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CPC-N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.37513 DMS79 CCLE Cell Line Gene CNV Profiles -1.0 -1.82095 RBM15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.19595 NCI-H2795 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.82816 H3K27ac_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null RCOR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null adrenal gland HPA Tissue Protein Expression Profiles -1.0 -1.51613 CREB1_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null OCILY19 DepMap CRISPR Gene Dependency 1.0 3.27319 LPIN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.71251 POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H2196 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.55423 ovary HPA Tissue Protein Expression Profiles -1.0 -1.51613 BPHL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3123 nb4 HPA Cell Line Gene Expression Profiles 1.0 1.1957 U937 CCLE Cell Line Gene Expression Profiles 1.0 1.52874 ELAC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13599 ZNF598 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40169 TBL1XR1 ENCODE Transcription Factor Targets 1.0 null GSN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19873 Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I7-06A-22R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XPVG-2926-SM-4B66G GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-POMQ-0008-SM-48TE7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 MKX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03541 GTEX-T6MN-0008-SM-4DM7H GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 entorhinal cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44614 GTEX-Q734-1826-SM-2I3EL GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 MSL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74546 GTEX-XBEC-0326-SM-4AT4M GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 Colon TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 primary motor cortex (area M1, area 4)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.92226 REST_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X4EO-0526-SM-3P5Z3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.42789 Lung squamous cell carcinoma_LUSC_TCGA-77-7139-01A-11R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_K562_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X8HC-1526-SM-46MWD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 SC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.48737 RANBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.70862 PLCB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.64214 GTEX-QCQG-2126-SM-2S1P8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.03515 POLR2A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SIN3A_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SW 900 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.951181 MKN-45 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.27888 OAW28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.951181 TMEM30A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57858 GTEX-RU72-0011-R11A-SM-2TF6J GTEx Tissue Sample Gene Expression Profiles 1.0 0.843308 NLGN4Y CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78852 H3K4me3_MEL cell line_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null eGFP-FOS_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZBTB7A ENCODE Transcription Factor Targets 1.0 null PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-HL-60-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_HL-60_LYL1 Rummagene Transcription Factor Associations 2026 1.0 null amygdaloid complex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.61957 medial part of r7B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02244 NR1H3-23393188-ATHEROSCLEROTIC-FOAM-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null LAMTOR4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04416 USF1_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null mantle zone of r2Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06589 BRMS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06098 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51G-06A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-OHPN-0226-SM-48TBV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-X3Y1-0626-SM-3P5YS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-N7MS-0126-SM-3TW8O GTEx Tissue Sample Gene Expression Profiles 1.0 0.87652 GTEX-U3ZN-2626-SM-3DB7T GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 ZNF155 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07716 CHD1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TP63-22573176-HFKS-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null POLR2A_MEL cell line_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null RXRB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57637 ZFP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14469 MRPL27 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95651 H3K4me3_fibroblast of lung_hg19_7 ENCODE Histone Modification Site Profiles 1.0 null PAX8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.618 Primary visual area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.60453 Ankyrin repeat InterPro Predicted Protein Domain Annotations 1.0 null mantle zone of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06474 USF1_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_17282_KO_Hsf5_SRP345601 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 E2F4_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-NL4W-0011-R8a-SM-2I3G4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-XUJ4-2126-SM-4BOOX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 EB1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.929589 GSE153871_1_v_2_cytarabine_human RummaGEO Drug Perturbation Signatures -1.0 null H3K27ac_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ACTC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88016 MAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78632 negative regulation of hydrolase activity GO Biological Process Annotations 2015 1.0 null H3K4me1_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null IRX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.09264 GABPA_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-Q734-0008-SM-48U2I GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 SPATA24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52464 mantle zone of ITTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13987 H3K79me2_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ALDH1B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99777 GTEX-OXRK-1826-SM-2HMJE GTEx Tissue Sample Gene Expression Profiles 1.0 1.57138 496100297_FWM_possible Alzheimer's disease_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.65824 H3K4me3_GM06990_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QESD-1626-SM-2S1RB GTEx Tissue Sample Gene Expression Profiles 1.0 1.17084 hsa-miR-548ab TargetScan Predicted Conserved microRNA Targets 1.0 0.568687 r6 part of rostral ventromedial reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.61537 LN229 CCLE Cell Line Gene CNV Profiles 1.0 1.61136 GTEX-S7PM-0626-SM-4AD4Q GTEx Tissue Sample Gene Expression Profiles 1.0 0.856728 GTEX-PVOW-0008-SM-48TE8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 SMYD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22957 GTEX-PWOO-1026-SM-48TCN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 H3K4me3_cardiac mesoderm_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null GSE146982_3_v_6_metformin_human RummaGEO Drug Perturbation Signatures -1.0 null SP4 ENCODE Transcription Factor Targets 1.0 null primary motor-sensory cortex (samples)_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.52191 GTEX-P4QT-0526-SM-2I3EX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-QDT8-1326-SM-48TYY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-PWN1-2426-SM-48TDD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-N7MT-1226-SM-2D7W4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 layer 3 of ERCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.98477 temporal pole, left, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.836259 NCCSTCK140 CCLE Cell Line Gene Expression Profiles -1.0 -2.32273 Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-A5NI-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRPF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86667 POLR2A_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null UQCR10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57224 Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SL-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAX_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of VTTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.93289 PAPSS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29065 PML_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MFM-223 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.84374 amygdaloid complex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.34928 orbital frontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.22869 VMRCLCD DepMap CRISPR Gene Dependency 1.0 4.36943 CTCF_K562_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-QH-A6X4-01A-51R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null medial geniculate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.93249 FOSL1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE92364_0_v_3_asparaginase_mouse RummaGEO Drug Perturbation Signatures -1.0 null NRF1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A657-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null STAT1 ENCODE Transcription Factor Targets 1.0 null Thymus-fast muscle cell Tabula Sapiens Gene-Cell Associations 1.0 2.91861 H3K4me3_HEK293_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null erg_19359602_huvec_lof_human_gpl570_gds3557 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -1.11238 MXI1_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Suprageniculate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.85636 gracile nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.5983 POLR2A_GM18951_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T2IS-3126-SM-32QPK GTEx Tissue Sample Gene Expression Profiles 1.0 0.935922 JUN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43524 GTEX-RVPU-2326-SM-2TF6R GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 BATF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94435 H3K4me2_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null FOSL2 ENCODE Transcription Factor Targets 1.0 null ATF3_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ETS1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null lung HPA Tissue Protein Expression Profiles -1.0 -0.738732 CHP-212 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.64204 MRPL50 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64013 POLR2AphosphoS5_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PUR1 MotifMap Predicted Transcription Factor Targets 1.0 null posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.22089 H3K4me1_MEL cell line_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WFON-0326-SM-3GIKX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A852-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PK-45P Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.946995 GSE166783_1_v_2_tp53_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-PWCY-0008-SM-48TE9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-T8EM-1326-SM-3DB7G GTEx Tissue Sample Gene Expression Profiles 1.0 1.28356 GTEX-RM2N-0006-SM-2TF5H GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-RWSA-0726-SM-2XCBE GTEx Tissue Sample Gene Expression Profiles 1.0 1.17173 KURAMOCHI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07566 HDQP1 CCLE Cell Line Gene CNV Profiles -1.0 -2.83354 STAT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55882 HPS4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7377 GTEX-S3XE-1126-SM-4AD4N GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 DOHH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53176 PMC8567280-EMBR-22-e53014-s007.xlsx-Sheet1-Nearest_genes_to_BAZ2A-bound_C2-Enhancers_BAZ2A Rummagene Transcription Factor Associations 2026 1.0 null GTEX-XOT4-0526-SM-4B66O GTEx Tissue Sample Gene Expression Profiles 1.0 1.30572 DLX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24545 H3K36me3_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100477_HIP_no dementia_TBI_89_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.00138 H3K9ac_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null MLH3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.72213 AP-4 MotifMap Predicted Transcription Factor Targets 1.0 null ventral isthmic part of dorsal raphe nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03378 BABAM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96271 ATF2_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null GTEX-Q2AI-1526-SM-3GIJ3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.91237 Ebf2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 31.1796 NCI-H716 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20756 GTEX-Q2AH-1126-SM-48TZM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GSE185519_3_v_2_gilteritinib_human RummaGEO Drug Perturbation Signatures -1.0 null HNRNPCL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8028 RXRG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 68.3983 POLR2A_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null precentral gyrus, left, superior lateral aspect of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.00189 CAPAN-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.961977 Piriform-amygdalar area, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34178 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3MA-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BEND3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79365 TRIM11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45218 RARG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.6466 LRRC40 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41701 PDXK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.36826 GTEX-R55D-0626-SM-3GAD5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.72837 Lung adenocarcinoma_LUAD_TCGA-53-7626-01A-12R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LCN12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03545 MSANTD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89872 H3K4me3_GM12864_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE76425_0_v_7_lenalidomide_human RummaGEO Drug Perturbation Signatures -1.0 null soft tissue HPA Tissue Protein Expression Profiles -1.0 -1.24818 PMC6870463-Table_7.xlsx-Family_H_No_LPS-Untreated_BMDMs_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null Brain Lower Grade Glioma_LGG_TCGA-RY-A843-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SMC3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null eGFP-JUNB_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2956-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-TKQ2-1526-SM-4DXUN GTEx Tissue Sample Gene Expression Profiles 1.0 0.839661 UQCRC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13407 GTEX-OIZI-0626-SM-2XCEH GTEx Tissue Sample Gene Expression Profiles 1.0 1.03441 OUMS-23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.2876 GSE125403_7_v_6_venetoclax_human RummaGEO Drug Perturbation Signatures 1.0 null MCTS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80843 MOLM13 CCLE Cell Line Gene Expression Profiles 1.0 2.42556 BEND4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4728 KP4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.993986 U118MG CCLE Cell Line Gene Expression Profiles -1.0 -1.6544 Perturb_7929_KD_ZCCHC8_SRP222099 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.88855 EFCAB14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.27801 CENPW CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82464 KAT2A_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TLX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4253 YY1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XGQ4-2226-SM-4AT4Y GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GSE215086_3_v_7_batf_human RummaGEO Gene Perturbation Signatures 1.0 null H3K9ac_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Uterine Carcinosarcoma_UCS_TCGA-NG-A4VU-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null phosphatase binding GO Molecular Function Annotations 2023 1.0 null ALKBH7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34428 LGALS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.90024 MAX_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PRR3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44314 GSE241701_2_v_0_daxx_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC3419980-leu201249x4.xls-POLII-RUNX1ETO_peaks_2fold-All_gene_regions_having_RUNX1_ETO_peaks_genes_where_PolII_changes_more_than_2-fold_RUNX1 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_brain microvascular endothelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_embryonic fibroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LBP-1 MotifMap Predicted Transcription Factor Targets 1.0 null TSKU CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03604 POLR2A_GM12891_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null COLO679 DepMap CRISPR Gene Dependency 1.0 4.05747 MDA-MB-436 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.84374 TANGO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00308 whole body TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 PMC9385264-NIHMS1828071-supplement-8.xlsx-ESR1-gene_symbol_ESR1 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SAP30_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TEAD4 ENCODE Transcription Factor Targets 1.0 null TBL1XR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE152441,GSE152442_6_v_4_folic acid_human RummaGEO Drug Perturbation Signatures -1.0 null HCC1187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.84374 MRPL47 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5837 Posterior parietal association areas, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.30018 H3K4me3_foreskin fibroblast_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-Q2AI-0826-SM-48TZO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 SYNDIG1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61782 INKA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84452 H3K4me1_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_astrocyte of the cerebellum_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-O5YW-3026-SM-3MJHI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 amygdaloid complex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.1232 UNC13D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.96322 H3K4me3_HeLa-S3_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null NELFE_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81977 dorsal raphe nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.20038 H3K4me3_skeletal muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-RM2N-0008-SM-48FF3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-R55C-1026-SM-48FCM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 negative regulation of phosphorus metabolic process GO Biological Process Annotations 2015 1.0 null intermediate stratum of CoPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14904 GTEX-OOBJ-0926-SM-48TDO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GSE229973_3_v_0_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null POLR2A_GM19099_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC7921413-41467_2021_21650_MOESM5_ESM.xlsx-002_DE-CD34_Blasts_AP1_high_JUN Rummagene Transcription Factor Associations 2026 1.0 null GTEX-P4QS-1626-SM-2S1NH GTEx Tissue Sample Gene Expression Profiles 1.0 1.37307 PPIL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27579 EGR1_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null KCNC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67102 anterior (rostral) cingulate (medial prefrontal) cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.50791 GTEX-NPJ8-1626-SM-2HMIY GTEx Tissue Sample Gene Expression Profiles 1.0 1.39149 Olfactory areas Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23452 HS695T DepMap CRISPR Gene Dependency 1.0 2.6651 ARHGEF10L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9888 HCC1833 CCLE Cell Line Gene Expression Profiles -1.0 -1.86947 RNF2 ENCODE Transcription Factor Targets 1.0 null GTEX-X4XX-0626-SM-3NMC1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.44243 Large intestine TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 pedunculo(pontine) tegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.00888 periventricular stratum of OB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08642 OVISE CCLE Cell Line Gene CNV Profiles -1.0 -1.60394 NCIH2030 CCLE Cell Line Gene CNV Profiles 1.0 1.35325 GTEX-S4P3-0006-SM-3K2AW GTEx Tissue Sample Gene Expression Profiles 1.0 0.827771 CDY1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61273 primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.13226 AP-2rep MotifMap Predicted Transcription Factor Targets 1.0 null VZ in midcingulate neocortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.02825 MAVER1 DepMap CRISPR Gene Dependency 1.0 2.29808 GSE188870,GSE188871_0_v_2_kat7_mouse RummaGEO Gene Perturbation Signatures 1.0 null H2AFZ_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Rectum adenocarcinoma_READ_TCGA-DY-A0XA-01A-11R-A155-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOS_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SIU8-0626-SM-2XCDN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 H3K4me3_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SLFN14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57168 GTEX-SNMC-0008-SM-4DM5A GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-PN-A8MA-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null DQX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.19886 SLC31A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70004 parvicellular (lateral) subparafascicular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06691 VZ in septal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.37252 VI, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.04463 COA6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27302 GATA2_G1E-ER4_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null TRIM46 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14136 TP53INP2_OE_GDS5054_276_mouse_SKM-Tg - Skeletal muscle GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Perturb_12951_KD_ALKBH5_SRP247667 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.41014 ARHGEF25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19592 PHF8_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CSNK1G3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56305 inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.835232 GSE120612_6_v_5_etoposide_human RummaGEO Drug Perturbation Signatures -1.0 null ZC3H11A ENCODE Transcription Factor Targets 1.0 null PMC5903287-NIHMS956886-supplement-Table_2.xls-THP1_THP3_cds_exp_down-gene_GLI2 Rummagene Transcription Factor Associations 2026 1.0 null GTF3C6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42295 hsa-miR-548n TargetScan Predicted Conserved microRNA Targets 1.0 0.670641 Uterine Carcinosarcoma_UCS_TCGA-N5-A4RA-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NELFE_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POU2F2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF687 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84001 EP300_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RKN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.30195 GTEX-RU1J-1726-SM-2TF5S GTEx Tissue Sample Gene Expression Profiles 1.0 1.22543 MDAMB157 CCLE Cell Line Gene CNV Profiles 1.0 1.32973 ACTR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32837 Lingula (I) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03517 POLR2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14782 lateral portion of the shell Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.948049 H3K4me3_CH12.LX_mm9_4 ENCODE Histone Modification Site Profiles 1.0 null ETS1 ENCODE Transcription Factor Targets 1.0 null GTEX-XLM4-0008-SM-4AT4W GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 N4BP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34813 DDB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66356 AOB, mitral cell layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09962 CEBPB_myocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HDAC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52744 H3K4me3_CH12.LX_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-SNMC-1426-SM-2XCFM GTEx Tissue Sample Gene Expression Profiles 1.0 1.35189 EEF1A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2911 Perturb_7768_KD_EXOC5_DRP001280 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.14587 hypoglossal nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.958242 H3K27ac_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ZCCHC12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.99069 binding GO Molecular Function Annotations 2015 1.0 null KHK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44642 SMARCC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66486 GTEX-QDVJ-0008-SM-48U2E GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-QDVN-1126-SM-48TZ7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 EGR1_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null lateral part of r7B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3463 H3K4me1_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null superficial stratum of r6BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22784 KALS1 CCLE Cell Line Gene CNV Profiles -1.0 -1.32399 CCNT2 ENCODE Transcription Factor Targets 1.0 null Brain Lower Grade Glioma_LGG_TCGA-E1-A7YK-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null USF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80094 GTEX-R53T-1226-SM-48FCT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 POLR2A_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NANS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84451 arcuate nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.31811 dorsolateral TG part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38248 STAT3 ENCODE Transcription Factor Targets 1.0 null H3K4me3_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CEP57 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12064 H3K9ac_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE212330_1_v_3_azacitidine_human RummaGEO Drug Perturbation Signatures 1.0 null TEAD4_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XUW1-0826-SM-4BOP6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.06052 dentate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.982244 JR DepMap CRISPR Gene Dependency 1.0 7.1889 DCPS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64007 PCCB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44838 BHLHE40_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE181821_1_v_3_mov10_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-RU72-1026-SM-46MUG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 BEND6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39567 HO1U1 DepMap CRISPR Gene Dependency 1.0 5.05698 USP32 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69597 DTX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6097 Lung squamous cell carcinoma_LUSC_TCGA-37-5819-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PHF11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97366 H3K4me3_fibroblast of upper leg skin_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null MAX_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Jun JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.0248 TTYH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31623 TFPI2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56228 MAX_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_7812_KD_RRP40_SRP091999 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 17.8794 vestibular nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.16513 ZNF789 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32494 biological regulation GO Biological Process Annotations 2015 1.0 null TT COSMIC Cell Line Gene Mutation Profiles 1.0 null Cortical amygdalar area, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27031 GTEX-P4PP-1626-SM-2HMJF GTEx Tissue Sample Gene Expression Profiles 1.0 1.31019 ZFYVE26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.452 TRAF7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84295 RXRA_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me2_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-N7MS-2625-SM-3LK77 GTEx Tissue Sample Gene Expression Profiles 1.0 1.00513 GTEX-QMRM-0008-SM-447B1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 SP1_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAFK_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null XPC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43333 SYNE4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83122 PA-TU-8988T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.64658 GTEX-UPJH-0126-SM-4IHLL GTEx Tissue Sample Gene Expression Profiles 1.0 0.872031 superficial stratum of r7BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.4484 principal sensory nucleus of trigeminal nerve Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.00947 GSE248045,GSE248046_6_v_5_runx1_mouse RummaGEO Gene Perturbation Signatures 1.0 null ELK4 ENCODE Transcription Factor Targets 1.0 null LOXL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6972 QSOX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34031 striatum_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.27443 MKN1 CCLE Cell Line Gene CNV Profiles -1.0 -1.41413 island of Calleja major Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24566 POLR2A_erythroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KDM4A ENCODE Transcription Factor Targets 1.0 null RMGI DepMap CRISPR Gene Dependency 1.0 3.06891 NCI-H250 COSMIC Cell Line Gene CNV Profiles 1.0 2.15316 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7091-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K36me3_G1E_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4761-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-05-4420-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BACH1 ENCODE Transcription Factor Targets 1.0 null regulation of cellular process GO Biological Process Annotations 2015 1.0 null KASUMI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.64204 STAT5A ENCODE Transcription Factor Targets 1.0 null TCF12_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NRF1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTF2F1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TM-A84I-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2AphosphoS5_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-Q2AH-1026-SM-48TZI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-Q2AH-1626-SM-3GAF8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 interleukin-23 receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.685 GTEX-XUZC-2026-SM-4BRW9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 H3K4me3_fibroblast of lung_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null TUBGCP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.10734 GTPBP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.07183 AUP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96111 GTEX-REY6-0526-SM-2TF5M GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 caudal ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.870735 DU4475 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.54338 Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A5KC-11A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NRL_Deficiency_GDS1693_238_mouse_Photoreceptors cells of retinas at P10 GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null BT-549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.08653 GTEX-R55G-2326-SM-2TC61 GTEx Tissue Sample Gene Expression Profiles 1.0 1.38368 mediodorsal nucleus of thalamus_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.22744 H3K27ac_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7406-11A-01R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27ac_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Entorhinal area, lateral part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18763 GTEX-OXRL-2126-SM-3NM98 GTEx Tissue Sample Gene Expression Profiles 1.0 0.88964 HPAF-II Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.935633 r6 part of basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05424 HNF4G_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_K562_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAF1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EGR1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null USF1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null brain TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null FLI1::DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.8876 GSE193258,GSE193259_9_v_3_osimertinib_human RummaGEO Drug Perturbation Signatures 1.0 null PPARG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.4643 POLR2A_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null COV644 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07566 GTEX-XOTO-0226-SM-4B66H GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 EP300_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZBTB11 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.9616 HES1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.8571 H3K4me3_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-17q25_3_TP63 Rummagene Transcription Factor Associations 2026 1.0 null Taenia tecta, dorsal part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05216 BRD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92459 GTEX-XBED-1426-SM-4AT4G GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 IP6K1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79516 Nr5a1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.5069 esophagus HPA Tissue Gene Expression Profiles 1.0 0.934149 H3K4me1_G1E-ER4_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XMK1-1826-SM-4B66F GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 888 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07699 DHCR24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.85564 PAX5_GM12878_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTF2F1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RNF220 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57733 dorsal motor nucleus of the vagus (vagal nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.01138 MYC_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SKCO1 CCLE Cell Line Gene CNV Profiles -1.0 -1.98045 Medial geniculate complex, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.96009 GTEX-X62O-0826-SM-46MW8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Gene_Name_HNF4A Rummagene Transcription Factor Associations 2026 1.0 null GSE152441,GSE152442_0_v_4_folic acid_human RummaGEO Drug Perturbation Signatures -1.0 null PAX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.6202 SORBS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.82275 GTEX-WYJK-1726-SM-3NM9U GTEx Tissue Sample Gene Expression Profiles 1.0 1.18867 GTEX-PLZ5-1726-SM-2I5F6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.17531 MHHNB11 DepMap CRISPR Gene Dependency 1.0 2.19965 KLC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84727 GTEX-RWS6-2126-SM-2XCAV GTEx Tissue Sample Gene Expression Profiles 1.0 1.08533 HNRNPUL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99017 KLHDC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.13088 Retrosplenial area, dorsal part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43597 GTEX-QVJO-0006-SM-2S1RC GTEx Tissue Sample Gene Expression Profiles 1.0 0.978711 RHBDD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52346 JUND_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_14185_KD_KDM1A_SRP289469 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 PPA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44948 POLR2A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NBEAL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7913 GTEX-RU72-3126-SM-46MUB GTEx Tissue Sample Gene Expression Profiles 1.0 0.960752 interstitial nucleus of Cajal, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.46649 POLR2A_bone marrow_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KAT7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90626 H2AFZ_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null dexamethasone_mus musculus_gpl6105_gse44208 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4960-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K36me3_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ANKIB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07576 Adrenocortical carcinoma_ACC_TCGA-PK-A5H9-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JURKAT DepMap CRISPR Gene Dependency 1.0 2.52774 GTEX-RTLS-0726-SM-46MV4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 RERF-GC-1B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.834631 SYNCRIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65202 POLR2A_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null UBC Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_fibroblast of upper leg skin_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE174701_1_v_2_maml3_human RummaGEO Gene Perturbation Signatures 1.0 null H3K9ac_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TAF1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null IZ in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.854718 Spinal vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0951 EGR1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Amp_AA-TCGA-Unnamed_20_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null Dermal microvascular endothelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.824 FEZ2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73834 layer III of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.987232 FUS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56861 enzyme binding GO Molecular Function Annotations 2015 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WO-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.22891 PSME3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49898 orbital frontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.64172 537 MEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.4709 GTEX-WZTO-0826-SM-3NM8Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.29516 Perturb_9025_KD_NR4A3_SRP324495 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.65643 SNU119 CCLE Cell Line Gene Expression Profiles -1.0 -1.75505 ZNF143 ENCODE Transcription Factor Targets 1.0 null GTEX-PW2O-1726-SM-2S1OO GTEx Tissue Sample Gene Expression Profiles 1.0 1.3806 H3K4me3_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.05481 G6PC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33403 chr17_81876479_A_T_b38 GTEx eQTL 2025 1.0 1.62294 TBP_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SK-MEL-5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.0119 NCI-H727 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14996 POLR2A_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_7745_KD_RRP6/DIS3_SRP062389 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 CDKN1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76932 SK-MEL-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26642 HSD3B7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27286 GTEX-PWCY-0526-SM-2I3ER GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 FAM124B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49374 MYC_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OE21 CCLE Cell Line Gene CNV Profiles 1.0 2.06999 Prostate adenocarcinoma_PRAD_TCGA-G9-6338-01A-12R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_fibroblast of lung_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null RABAC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03396 H3K4me1_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-94-7033-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_B cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null precentral gyrus, right, inferior lateral aspect of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.43955 ORAI2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14238 m1AD (DM) part of periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.40422 IMR-32 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07971 negative regulation of phosphate metabolic process GO Biological Process Annotations 2015 1.0 null GTEX-QLQ7-1726-SM-2S1QQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.25852 H3K4me1_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TXK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41458 ZNF404 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37638 PPP4R2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99914 DMRTC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33114 protein binding GO Molecular Function Annotations 2015 1.0 null OVCAR-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.870191 Perturb_7758_KD_MTREX_SRP337423 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.21617 YY1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ATF3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ME-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.33708 ZMIZ1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.855736 GTEX-S4Z8-0008-SM-33HAZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 CTCF_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XYKS-1826-SM-4E3JV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.56362 H3K27ac_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TCF12 ENCODE Transcription Factor Targets 1.0 null TMEM185B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.48022 POLR2A_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ELK1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RNF214 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82647 ELF1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WFG7-2226-SM-3GIKP GTEx Tissue Sample Gene Expression Profiles 1.0 1.62449 NKX6-1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02165 TP53 ChEA Transcription Factor Targets 1.0 null DUS1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40325 POU2F2_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CPHXL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57806 L540 CCLE Cell Line Gene CNV Profiles -1.0 -1.67246 GTEX-WY7C-2526-SM-3NB2N GTEx Tissue Sample Gene Expression Profiles 1.0 1.0722 EP300_GM12878_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null SP1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32764 E2F4_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1435 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.955744 Perturb_7652_KD_RRP40_SRP126942 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 16.4872 SIG-M5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 3.24385 H3K4me3_H7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null REST ENCODE Transcription Factor Targets 1.0 null ADGRG5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79734 OLIG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13044 H3K4me3_G1E-ER4_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-Q2AH-0726-SM-2I3EA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-WL46-0726-SM-3LK5Z GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 NCIH3255 CCLE Cell Line Gene Expression Profiles -1.0 -2.26468 GTEX-WEY5-2126-SM-3GILK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.23597 lateral parabrachial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.43905 H3K4me2_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WHPG-2226-SM-3NMBO GTEx Tissue Sample Gene Expression Profiles 1.0 1.53827 MRPL19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11983 Perturb_8940_Mut_RB1_SRP220467 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 18.6778 PAFAH1B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79393 FOXRED2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00843 GTEX-P4QT-2426-SM-3NMCL GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 lateral posterior nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.826763 H2AFZ_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOS::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.6926 PCNX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41109 GTEX-XXEK-0526-SM-4BRWD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43U-01A-11R-A23W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-OOBK-1626-SM-2HMKG GTEx Tissue Sample Gene Expression Profiles 1.0 2.36094 POLR2A_GM19193_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-5962-01B-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GABPA_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KMBC2 DepMap CRISPR Gene Dependency 1.0 2.36754 medial parabrachial nucleus,right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.77027 TP63 JASPAR Predicted Transcription Factor Targets 1.0 null H3K27ac_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PPARD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.13152 H3K4me3_GM12875_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QXCU-0006-SM-2TC5K GTEx Tissue Sample Gene Expression Profiles 1.0 0.8411 GTEX-QMR6-1926-SM-32PL9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 Perturb_13503_KD_CEBPG_SRP324237 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 CHD2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SIU8-0006-SM-2XCE5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.879164 ZBTB7C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.3342 PFEIFFER Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07699 TRIM45 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33994 ZDHHC13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.00998 GABPA_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null posteromedial visual area, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21196 GSE185519_6_v_2_gilteritinib_human RummaGEO Drug Perturbation Signatures -1.0 null OCI-AML3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.03906 H3K36me3_CH12.LX_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SHQ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62367 GTEX-Q2AG-3026-SM-48U1L GTEx Tissue Sample Gene Expression Profiles 1.0 0.981534 GTEX-UJMC-0726-SM-3GADX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 POLR2A_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PSDG-0826-SM-48TCZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 H3K4me3_cardiac mesoderm_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null EGR1_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZEB1 ENCODE Transcription Factor Targets 1.0 null intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null AFF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30355 GTEX-R55D-1426-SM-48FEN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 retrotrapezoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2273 GTEX-U8T8-1426-SM-3DB9H GTEx Tissue Sample Gene Expression Profiles 1.0 2.35019 GTEX-QDT8-0226-SM-32PL4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 MAPK14_knockdown_139_GSE31912 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.33849 SAP30_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAF1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X5EB-2026-SM-4E3KA GTEx Tissue Sample Gene Expression Profiles 1.0 0.857578 BRCA1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EBF1 ENCODE Transcription Factor Targets 1.0 null SLC38A10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96081 RORB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.81535 HCC2270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20628 ALPL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42243 NFIX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77601 MAX_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null LTBP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38235 PPARD JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.4133 Entorhinal area, medial part, ventral zone, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32013 H2AFZ_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE162575,GSE162609_3_v_2_tfe3_human RummaGEO Gene Perturbation Signatures -1.0 null TAL1 ENCODE Transcription Factor Targets 1.0 null POLR2A_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null HSP90AA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33833 STX12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71861 496100527_FWM_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.81501 layer 6 of PCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00538 TAF1_GM12892_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6I0-11A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MTG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45037 HAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45103 JHH-5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06394 Basomedial amygdalar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00131 MYC_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Entorhinal area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.17231 EP300_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100470_HIP_possible Alzheimer's disease_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.81212 X, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.05791 CEBPD_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RPL22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00157 IL27RA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54101 POLR2A_GM15510_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ECHDC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28919 E2F1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null APBA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.80241 ZNF143 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.0717 PL21 CCLE Cell Line Gene Expression Profiles 1.0 1.51479 MAZ_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EW1 DepMap CRISPR Gene Dependency 1.0 2.05421 B4GALNT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1503 SNU738 CCLE Cell Line Gene CNV Profiles -1.0 -1.71682 NCKAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98288 SK-MEL-28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.2451 PMC5927328-NIHMS77085-supplement-Table_S4.xlsx-Table_S4A_LPS_induced_genes_GO-Unnamed_3_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null ETS1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CLK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69113 FAM83F CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53553 LN235 CCLE Cell Line Gene Expression Profiles -1.0 -1.5762 H3K27ac_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null SMIM26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26325 primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.882426 H3K4me3_LNCaP clone FGC_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QMRM-0926-SM-447BR GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-XQ8I-0926-SM-4BOOF GTEx Tissue Sample Gene Expression Profiles 1.0 0.878089 DU4475 CCLE Cell Line Gene Expression Profiles 1.0 1.70264 NME6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90787 GTEX-XQ3S-0426-SM-4BOOA GTEx Tissue Sample Gene Expression Profiles 1.0 1.21365 negative regulation of cellular metabolic process GO Biological Process Annotations 2015 1.0 null GTEX-PX3G-1626-SM-2S1PT GTEx Tissue Sample Gene Expression Profiles 1.0 1.45343 CHD1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DA-33-BM26_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.614582 ETS1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QLQ7-1926-SM-2S1R6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.882533 GSS CCLE Cell Line Gene Expression Profiles -1.0 -1.82114 regulation of dephosphorylation GO Biological Process Annotations 2015 1.0 null GTEX-X4XX-0011-R11A-SM-46MWQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 RFX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.302 MYC_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Nr2f6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 65.4383 GTEX-S32W-2326-SM-2XCAW GTEx Tissue Sample Gene Expression Profiles 1.0 1.28809 H3K4me3_HCT116_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null layer 2 of ERCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.992 Variable age at onset electroclinical syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.384 PMC8494348-pone.0257161.s002.xlsx-D20-NOT_ext_ext-NOT_ext-Gene_Name_NR4A2 Rummagene Transcription Factor Associations 2026 1.0 null H3K9ac_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Rarg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 76.8004 Adrenocortical carcinoma_ACC_TCGA-OR-A5K0-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K79me2_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PARP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56103 SPSB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54063 ESR2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 57.7111 Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I4-06A-11R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZKSCAN1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SLC5A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10898 KASUMI6 CCLE Cell Line Gene Expression Profiles 1.0 1.37048 EGR1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null animal TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 SP1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S4Z8-1826-SM-3K2BH GTEx Tissue Sample Gene Expression Profiles 1.0 1.97658 hsa-miR-548t TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EA-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null layer III of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.22144 GTEX-SIU7-1826-SM-2XCE2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.12514 parabigeminal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.12263 cochlear nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.61438 H3K4me1_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Perturb_13501_KD_WDR5_SRP261594 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 Posterior parietal association areas, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48716 Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HT-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-T5JC-0626-SM-3NMA6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.62752 WDR89 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08218 ASPC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.29379 H3K4me3_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_bronchial epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ITPK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34052 H3K4me2_myocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-S7SE-0326-SM-4AT5Q GTEx Tissue Sample Gene Expression Profiles 1.0 0.900692 MITF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.1931 SK-N-AS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.6368 Entorhinal area, medial part, dorsal zone, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.20181 SP1 ENCODE Transcription Factor Targets 1.0 null RXRA_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CAPAN-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14996 planum polare, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.01338 TYK-NU Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.934554 PAX9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.1062 Superior colliculus, motor related, intermediate gray layer, sublayer c Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.05908 FBLIM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21975 GTEX-U3ZH-1926-SM-4DXTR GTEx Tissue Sample Gene Expression Profiles 1.0 3.76974 KPL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.859165 RCAN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95717 POLR2AphosphoS2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null USF1_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CACFD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78009 PMC12754469-ab-25-0159-Supplementary-1.pdf-37-TBX18_TBX18 Rummagene Transcription Factor Associations 2026 1.0 null PEO4 DepMap CRISPR Gene Dependency 1.0 4.41483 RABGGTB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65945 GTEX-RTLS-0526-SM-2TF64 GTEx Tissue Sample Gene Expression Profiles 1.0 1.26716 BHLHE41 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.4144 POLR2AphosphoS2_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE80098,GSE80366_0_v_5_progesterone_human RummaGEO Drug Perturbation Signatures -1.0 null MAZ_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null THP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.75754 GTEX-QVUS-0008-SM-447AY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 MAX_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC8390401-12094_2021_2621_MOESM2_ESM.xls-S5-Supplemental_Table_S5_Differentially_expressed_genes_between_cases_with_CM-induced_pY-STAT3_DMFI_1_76_STAT3_Low_v_DMFI_1_76_STAT3_High_STAT3 Rummagene Transcription Factor Associations 2026 1.0 null GSE186633_2_v_0_chd1_human RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_Caco-2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null C2orf81 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11998 EPS8L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55221 GTEX-V955-0426-SM-3GAEL GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 JUND_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNU-601 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.84374 MXI1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OHPK-1526-SM-3MJGM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 RARA::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.5652 hsa-miR-27b TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 H3K4me1_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HS 839.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.869617 Rectum adenocarcinoma_READ_TCGA-DY-A1H8-01A-21R-A155-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CP67-MEL COSMIC Cell Line Gene Mutation Profiles 1.0 null Primary visual area, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -3.01428 496100614_PCx_no dementia_TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.17373 H3K4me3_cardiac mesoderm_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PHLPP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8616 PMC8390401-12094_2021_2621_MOESM2_ESM.xls-S4-Supplemental_Table_S4_Differentially_expressed_genes_between_cases_with_G-CSF-induced_pY-STAT3_DMFI_1_5_STAT3_Low_v_DMFI_1_5_STAT3_High_STAT3 Rummagene Transcription Factor Associations 2026 1.0 null ZNF143_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1 ENCODE Transcription Factor Targets 1.0 null GSE131649_2_v_7_hemin_human RummaGEO Drug Perturbation Signatures 1.0 null TALDO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.86495 hsa-miR-559 TargetScan Predicted Conserved microRNA Targets 1.0 0.766596 PMC11067031-pnas.2317690121.sd05.xlsx-Sheet1-Differentially_expressed_genes_between_PML_RARA_GFP_vs_Empty_vector_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Accessory olfactory bulb, glomerular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.76931 SMIM10L2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0197 GTEX-REY6-1426-SM-48FDK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 PML ENCODE Transcription Factor Targets 1.0 null ELF1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE169571_3_v_2_dexamethasone_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE240258_0_v_1_prmt1_human RummaGEO Gene Perturbation Signatures -1.0 null deltaEF1 MotifMap Predicted Transcription Factor Targets 1.0 null dorsolateral SC part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22052 CLEC11A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86553 NCI-H847 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.63801 WASF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39964 RNF141 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27533 GTEX-WVLH-0011-R6A-SM-3MJFZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 superficial stratum of InsCx (cortical plate/marginal zone) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06264 Ventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05424 GSE223893_11_v_9_setd2_human RummaGEO Gene Perturbation Signatures -1.0 null C3A CCLE Cell Line Gene Expression Profiles 1.0 1.45615 GTEX-XQ3S-2726-SM-4BOP2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.918729 GSE201309_4_v_2_matrine_human RummaGEO Drug Perturbation Signatures -1.0 null STXBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43956 Stat5a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.0922 HSD17B4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56283 MYC ENCODE Transcription Factor Targets 1.0 null GTEX-P4PP-0926-SM-48TBZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GSE152441,GSE152442_1_v_4_folic acid_human RummaGEO Drug Perturbation Signatures -1.0 null POLR2A_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EP300_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYBL2 ENCODE Transcription Factor Targets 1.0 null DMS 79 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.16162 GTEX-XXEK-0926-SM-4BRWH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 ZNF644 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46021 SMIM14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15981 KNSTRN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87021 periventricular stratum of m2ADL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00003 KE39 CCLE Cell Line Gene CNV Profiles -1.0 -1.36991 BST2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.82319 Retrosplenial area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10815 NR2C1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.7611 YY1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TE15 CCLE Cell Line Gene CNV Profiles 1.0 1.42468 NRF1 ENCODE Transcription Factor Targets 1.0 null HCFC1 ENCODE Transcription Factor Targets 1.0 null H3K79me2_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HQ-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ECHDC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1269 E2F1 ChEA Transcription Factor Targets 1.0 null KMS-21BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.05108 H3K4me3_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_8946_Mut_RB1_SRP220467 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 7.10591 POLR2AphosphoS5_Panc1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAOK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94613 Primary hematopoietic stem cells G-CSF-mobilized Female RO_01536 Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 0.893311 BRCA1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null superior occipital gyrus, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.985888 H3K9ac_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null USF1 ENCODE Transcription Factor Targets 1.0 null hippocampus (hippocampal formation)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.09097 H3K4me3_A549_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QDT8-0526-SM-3NMD8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.229 HNF4A_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MTLN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.509 Entorhinal area, medial part, dorsal zone, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.75038 H3K4me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CHD2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAP3K11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.94336 ATPSCKMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8857 ZBTB33_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mantle zone of r6BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32558 RBBP5 ENCODE Transcription Factor Targets 1.0 null stratum pyramidale of rostral CA2 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.956504 RXRA ENCODE Transcription Factor Targets 1.0 null H3K4me3_retinal pigment epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of the aortic adventitia_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null RNF130 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19453 TBL1XR1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QDT8-1026-SM-43V6X GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 CTCF_WERI-Rb-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_8954_Mut_RB1_SRP220467 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 PPP1R17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30605 BRCA1 ENCODE Transcription Factor Targets 1.0 null layer 1 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25713 GTEX-R55F-1526-SM-2TF4X GTEx Tissue Sample Gene Expression Profiles 1.0 2.32046 ATF1 ENCODE Transcription Factor Targets 1.0 null Perturb_737_KD_CHD4_SRP123294 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -14.5571 Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A9DD-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1171 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.932908 GTEX-SNOS-1526-SM-32PLW GTEx Tissue Sample Gene Expression Profiles 1.0 1.40592 IER5L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.73072 H3K4me3_astrocyte of the cerebellum_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null EGR1_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null E2F6_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OOBK-2126-SM-3LK5T GTEx Tissue Sample Gene Expression Profiles 1.0 0.877888 YY1_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Esrrg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 31.7958 Posterior limiting nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.48228 COV318 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.874123 TKFC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45916 Anterolateral visual area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00331 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5875-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF572 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23744 body of caudate Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.934952 ZEB1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null LASV_FML29_8hr_24069471_GSE41300 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -3.34459 Perturb_13502_KD_WDR5_SRP321449 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.10259 Medial geniculate complex, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.58684 MV-4-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.92378 IB-33-TE51_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 1.36345 Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J5-01A-21R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null E2F2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55058 FADU Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.988896 GTEX-P44H-0726-SM-48TBT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 TAF1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RCOR1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-VJWN-0426-SM-3GIJI GTEx Tissue Sample Gene Expression Profiles 1.0 1.88928 KYSE-270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.07937 NCI-H2172 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.03332 SK-CO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.43974 SOCS7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.80192 GTEX-POYW-0526-SM-2XCEY GTEx Tissue Sample Gene Expression Profiles 1.0 1.11744 GTEX-OOBK-0726-SM-3LK5Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-QMRM-0826-SM-3NB33 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 PMC4856960-supp_gkv1471_nar-01762-z-2015-File012.xlsx-GO_common_7H-HIF1_chip-Common_elements_in_chip7h_and_chip_hif1_2530_official_gene_symbols_HIF1A Rummagene Transcription Factor Associations 2026 1.0 null QKI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83771 A2780 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.3733 GSE160373_5_v_7_pparg_mouse RummaGEO Gene Perturbation Signatures 1.0 null SUDS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31329 GTEX-PSDG-0008-SM-48TE5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 RABEP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98313 GTEX-QLQW-0626-SM-447A6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 ZNF846 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5185 Perturb_7811_KD_MTREX_SRP091999 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 outer portion of lateral ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.875067 Primary somatosensory area, unassigned Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00736 SIN3A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NAA10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.14553 MDA-MB-436 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.32143 OVKATE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.06213 GTEX-S4P3-0526-SM-4AD58 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 HTR1D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1147 regulation of molecular function GO Biological Process Annotations 2015 1.0 null EOL1 CCLE Cell Line Gene Expression Profiles 1.0 2.02064 CHCHD7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69447 PPP1R26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30015 GTEX-R55C-0626-SM-2TF4Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GGA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13893 GTEX-WRHU-1026-SM-4E3ID GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-UPJH-0526-SM-4IHK8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.367 Lung squamous cell carcinoma_LUSC_TCGA-37-A5EL-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null eGFP-JUND_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CNTROB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44938 GTEX-X8HC-0226-SM-4E3K1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 RPS9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.23608 GTEX-R55C-0726-SM-48FCN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-XBEW-0126-SM-4AT66 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 Lassa Fever Virus_4hr_24069471_GSE41300 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 3.26162 COR-L88 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.848766 GABPA_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC4823830-ncomms11171-s2.xlsx-GATA3_upregulated_genes-GeneSymbol_GATA3 Rummagene Transcription Factor Associations 2026 1.0 null IRF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-TKQ2-0826-SM-33HB6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.24667 ARHGEF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45699 CTNNA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30397 Perturb_12975_KO_YTHDF2_SRP365416 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 basomedial amygdaloid nucleus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12196 H2AFZ_B cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S4UY-0006-SM-3K2A7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.972715 ERCC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67397 ZIM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0904 cingulate cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03309 GTEX-PX3G-0426-SM-48U1C GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 H3K4me3_cardiac muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GZF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.07103 POLR2AphosphoS5_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ES-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.904495 GABPA_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_HeLa-S3_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null UFSP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35324 GSE199204,GSE211619_4_v_1_glutamine_human RummaGEO Drug Perturbation Signatures -1.0 null EBF1_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null TOB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.3018 H3K9me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-PWOO-1326-SM-48TCJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 EP300 ENCODE Transcription Factor Targets 1.0 null SU-DHL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.35139 MYC_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OHPM-2126-SM-3LK75 GTEx Tissue Sample Gene Expression Profiles 1.0 0.838078 ZBTB7B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.0488 r3 part of basomedial reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.55429 LASV_FML29_24hr_24069471_GSE41300 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 0.787417 H3K4me3_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null F11R CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0751 E2F6_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SLR20 CCLE Cell Line Gene CNV Profiles -1.0 -1.43509 USF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.8213 USF1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100459_PCx_no dementia_no TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.52973 NFIC_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-V9-A7HT-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HLTF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40956 YWHAB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78938 MAN2C1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49433 H3K4me3_MEL cell line_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null P4HA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73074 GTEX-SNOS-1126-SM-4DM67 GTEx Tissue Sample Gene Expression Profiles 1.0 0.869942 superficial stratum of ITTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.50814 ERBB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5018 Calcaneal bone TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.561 C11orf86 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45681 RNA polymerase II termination complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.79 GTEX-O5YT-1626-SM-32PK6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.65091 POLR2AphosphoS5_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JHH-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.84374 H3K4me3_cardiac mesoderm_hg19_5 ENCODE Histone Modification Site Profiles 1.0 null ZNF236 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29257 GOLIM4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5978 CAR-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20756 496100537_FWM_no dementia_TBI_87_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.12196 HNF4G_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X3Y1-0726-SM-3P5YU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-P78B-0826-SM-3NMCA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-X5EB-1426-SM-46MVW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 PE01 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.72299 molecular function regulator GO Molecular Function Annotations 2015 1.0 null NCIH1915 CCLE Cell Line Gene CNV Profiles 1.0 1.57397 tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.04991 dorsal part of m1A Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.40422 CBL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7551 H3K4me1_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BCAS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27404 GSE131649_6_v_7_hemin_human RummaGEO Drug Perturbation Signatures 1.0 null H3K79me2_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null U-937 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.46331 hsa-miR-548ak TargetScan Predicted Conserved microRNA Targets 1.0 0.632343 OLA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42392 GTEX-RUSQ-2126-SM-47JXK GTEx Tissue Sample Gene Expression Profiles 1.0 0.897964 POGLUT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26761 medial ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.11219 OCIAML3 CCLE Cell Line Gene Expression Profiles 1.0 1.79979 RARA::RXRG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.4073 IRF1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null FASTKD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.60978 CPCN CCLE Cell Line Gene Expression Profiles 1.0 1.6544 mantle zone of r3BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06688 H3K4me3_astrocyte of the spinal cord_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_WERI-Rb-1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null NUP35 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31839 MTA3 ENCODE Transcription Factor Targets 1.0 null GTEX-XBED-0926-SM-48TCE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 Retrosplenial area, ventral part, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23835 Posterior parietal association areas, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.20181 fibro-adipogenic progenitor cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.81 OVOL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26763 D502MG DepMap CRISPR Gene Dependency 1.0 2.52427 AHCY CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97664 NFAT5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82024 BCL3 ENCODE Transcription Factor Targets 1.0 null SSBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71114 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4337-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_limb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null V-79 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.708 PLEKHG4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35389 Sarcoma_SARC_TCGA-K1-A6RT-01A-32R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CNST CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98051 superficial stratum of r7BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.97165 UHRF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28941 cingulate gyrus, retrosplenial part, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.34644 GABPA_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE240439_1_v_2_decitabine_human RummaGEO Drug Perturbation Signatures 1.0 null regulation of phosphate metabolic process GO Biological Process Annotations 2015 1.0 null SETD1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10483 intermediate stratum of the VAP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05632 Lafora disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.602 Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QX-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-SY-A9G5-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U3ZH-0626-SM-4DXT3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 PMC7880998-41467_2021_21255_MOESM8_ESM.xlsx-Sup_Data_5_TWIST_Panel-Gene_Name_TWIST1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-XV7Q-2226-SM-4BRVY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 PCCA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82611 intergeniculate leaflet Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34829 NRF1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Primary somatosensory area, unassigned, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.55086 GTEX-OHPL-1626-SM-2HMIR GTEx Tissue Sample Gene Expression Profiles 1.0 1.883 Ptf1a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 54.9225 TBC1D10B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92403 GTEX-POMQ-1926-SM-3NB1Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.49242 H3K4me3_fibroblast of pedal digit skin_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null STAT5A_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXP2_PFSK-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 21205295-TableS1 GeneSigDB Published Gene Signatures 1.0 null GSE110440_1_v_3_rad21_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-QCQG-0426-SM-48U29 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 NRF1 Pathway Commons Protein-Protein Interactions 1.0 null NCIH1385 CCLE Cell Line Gene CNV Profiles 1.0 1.33621 POLR2AphosphoS2_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mantle zone of VTTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.61476 MBD4 ENCODE Transcription Factor Targets 1.0 null H3K4me3_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QEL4-0008-SM-447AZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 H3K4me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-4755-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.517189 negative regulation of catalytic activity GO Biological Process Annotations 2015 1.0 null E2F6_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ERBB3_knockout_239_GSE32129 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 0.71672 NR2F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.5535 KYSE-70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20628 hsa-miR-548y TargetScan Predicted Conserved microRNA Targets 1.0 0.714812 C-33 A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.11732 HCC70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.69847 H3K4me3_skeletal muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null phosphatase binding GO Molecular Function Annotations 2015 1.0 null HIKESHI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24025 HAUS7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48106 H3K27ac_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TBR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28329 vertebrate muscular system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 CHP126 CCLE Cell Line Gene CNV Profiles 1.0 1.58612 ZFPL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98728 intermediate part of r6B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32476 TADA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83335 ELF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XPVG-2526-SM-4B66D GTEx Tissue Sample Gene Expression Profiles 1.0 1.21841 STAT5A_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null inner CP in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.04072 POLR2AphosphoS5_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null E2F4 ENCODE Transcription Factor Targets 1.0 null GTEX-NPJ7-0011-R6a-SM-2I3G7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 H3K4me1_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-98-A53I-01A-31R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PSPH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88854 stratum pyramidale of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.29253 GTEX-SSA3-0326-SM-32QPS GTEx Tissue Sample Gene Expression Profiles 1.0 1.95554 FGF19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.09394 PATU8988S CCLE Cell Line Gene CNV Profiles -1.0 -1.52463 Perturb_7760_KD_RRP6/DIS3_SRP337423 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.16042 GTEX-NL3H-0011-R1a-SM-48TDJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 H3K4me1_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PAPOLA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59217 GSE168797_1_v_6_cannabidiol_human RummaGEO Drug Perturbation Signatures 1.0 null POLR2A_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WOFL-0626-SM-3MJG3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.05761 GTEX-S341-0426-SM-4AD5L GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-SUCS-1326-SM-4DM5T GTEx Tissue Sample Gene Expression Profiles 1.0 0.883991 H3K4me3_WI38_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QLQW-1326-SM-2S1QS GTEx Tissue Sample Gene Expression Profiles 1.0 1.28728 NIH:OVCAR-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.72299 hippocampus (hippocampal formation)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.64672 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6017-01A-11R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SG in midlateral extrastriate cortex (area 19) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.960036 MBD4_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U3ZH-0008-SM-4DXT2 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 HNF4A JASPAR Predicted Transcription Factor Targets 1.0 null GSE205332_1_v_0_queuine_human RummaGEO Drug Perturbation Signatures 1.0 null posteroventral (inferior) parietal cortex_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.62511 H3K4me3_fibroblast of lung_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null USF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LN-229 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.971507 VZ in dorsomedial extrastriate cortex (V2) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.9439 GTEX-PX3G-1526-SM-48U11 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GABP-19822575-HepG2-human ChEA Transcription Factor Binding Site Profiles 1.0 null COLO-818 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14996 REST_PFSK-1_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null r7 part of rostral ventromedial reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.23397 enzyme inhibitor activity GO Molecular Function Annotations 2015 1.0 null H3K4me3_astrocyte of the spinal cord_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-RTLS-2426-SM-46MUO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 periventricular stratum of SC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18054 MYC_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OTULINL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.43471 PAX5 ENCODE Transcription Factor Targets 1.0 null SREK1IP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11414 GSE200099_3_v_1_honokiol_human RummaGEO Drug Perturbation Signatures 1.0 null HS 578T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.935633 EGR1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null WSCD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88651 L3MBTL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.72269 ICAM5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28791 GTEX-S7SF-1026-SM-4AD4I GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GSE185519_6_v_0_gilteritinib_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-OHPL-0426-SM-3TW8X GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 mantle zone of CCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03238 POLR2A_A549_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null SKNAS CCLE Cell Line Gene CNV Profiles 1.0 1.91486 NTERA-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.12939 inner CP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.838639 GTEX-U8XE-0726-SM-3DB8O GTEx Tissue Sample Gene Expression Profiles 1.0 2.86441 CEBPD_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Agranular insular area, dorsal part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41937 Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A5KD-11A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TUBA1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.92201 negative regulation of dephosphorylation GO Biological Process Annotations 2015 1.0 null DYNC1H1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67025 FBXO38 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61048 COLO201 DepMap CRISPR Gene Dependency 1.0 2.15606 H2AFZ_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SNMC-1526-SM-2XCFN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 TCF12_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ITGB4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9817 ERF::SREBF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1914 JAGN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69426 RXRG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.278 Retrosplenial area, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05804 ZEB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.2948 BLOC1S2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3038 ADPRS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53724 Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A764-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hippocampus (hippocampal formation)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.89575 Cortical amygdalar area, posterior part, medial zone, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37008 H3K4me3_fibroblast of foreskin _hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QCQG-1526-SM-48U25 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 ELK4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42702 SLC30A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10886 GTEX-WOFM-1326-SM-3MJFR GTEx Tissue Sample Gene Expression Profiles 1.0 1.01628 dorsolateral prefrontal cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.01258 protein phosphatase regulator activity GO Molecular Function Annotations 2015 1.0 null H3K36me3_G1E-ER4_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GABPA_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of r3BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06688 CREB1-20920259-GC1-SPG-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null HOXB2::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.997 skbr3 HPA Cell Line Gene Expression Profiles 1.0 0.83551 CTCF_HepG2_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC5358377-pnas.1615015114.sd02.xlsx-Sheet1-genes_with_VDR_peaks_with_and_without_D3_VDR Rummagene Transcription Factor Associations 2026 1.0 null E2F1-21310950-MCF7-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null FLVCR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8669 RXRB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 51.2867 GTEX-SJXC-0526-SM-2XCFG GTEx Tissue Sample Gene Expression Profiles 1.0 1.1479 PMC4487811-mmc3.xlsx-siRE_enriched_geneLists-siRE_occupancy_pattern_gene_lists_after_RUNX1_ETO_knock_down_RUNX1 Rummagene Transcription Factor Associations 2026 1.0 null RCC10RGB DepMap CRISPR Gene Dependency 1.0 2.26137 H3K4me3_HepG2_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Perturb_7928_KD_EXOSC3_SRP222099 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.57664 LSM5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15465 ZNF197 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22453 NRF1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null t55-gastrocnemius_consensus MoTrPAC Rat Endurance Exercise Training 1.0 2.10737 PRPF4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29125 DNAJB4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16232 ZNF667 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.7559 Primary visual area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.86086 GTEX-WFG7-0526-SM-3GIKI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 H2AFZ_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XUJ4-2626-SM-4BOQ3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.32577 ZNF714 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10606 PSKH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55992 Prostate adenocarcinoma_PRAD_TCGA-VP-A87E-01A-31R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null layer V of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.898996 pioglitazone_homo sapiens_gpl570_gds4132 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-OXRN-2626-SM-48TBX GTEx Tissue Sample Gene Expression Profiles 1.0 0.953247 Msgn1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.6384 H3K36me3_G1E-ER4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_GM12892_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pparg::Rxra JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 35.3582 primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.33113 POLR2A_GM12878_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-Q2AH-0626-SM-48TZJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-common-common_genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_NB4_HL-60_and_Kasumi-1_LYL1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-S7SF-2026-SM-3K2AS GTEx Tissue Sample Gene Expression Profiles 1.0 1.44634 CREB1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null r7 part of basolateral reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3491 MFM-223 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.32143 REST_Panc1_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MT-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null regulation of biological process GO Biological Process Annotations 2015 1.0 null Accessory olfactory bulb, mitral layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44614 Primary somatosensory area, unassigned, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37864 RIOX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14777 POLR2A_olfactory bulb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 COLO668 CCLE Cell Line Gene CNV Profiles -1.0 -1.66455 SIX5_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PHF8_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-P44H-0426-SM-2XCEZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.0206 Perturb_4387_KO_STAG2_SRP348449 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 POLR2AphosphoS5_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-85-A512-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE241701_4_v_3_daxx_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_fibroblast of lung_hg19_5 ENCODE Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-43-A56V-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SOD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26396 H3K4me3_WERI-Rb-1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-S7SE-0011-R2A-SM-2XCDC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-QEG5-0426-SM-2I5GJ GTEx Tissue Sample Gene Expression Profiles 1.0 2.51634 H3K4me2_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H8-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-REY6-1126-SM-48FDU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 H3K36me3_G1E-ER4_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsolateral prefrontal cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.897351 nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.2317 GTEX-WL46-3026-SM-3LK7Z GTEx Tissue Sample Gene Expression Profiles 1.0 0.926888 GTEX-X5EB-0426-SM-46MVY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 496100596_FWM_dementia_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.40037 supramarginal gyrus, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.840392 upper limb region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.959637 ZNF384_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LEMD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94175 JUND ENCODE Transcription Factor Targets 1.0 null H2AK5ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null HCC515 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16382 SP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.01814 NRF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KLF15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8213 Pancreatic adenocarcinoma_PAAD_TCGA-LB-A8F3-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95975 POLR2A_K562_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of r6BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59905 TRIP12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.19129 Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RH-01A-12R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GATA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.2578 ATF7IP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81306 DAN-G Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.5665 H3K4me3_cardiac mesoderm_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WFG8-0926-SM-3GIKJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 RAD21_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZBTB33_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-Q734-2026-SM-3GADA GTEx Tissue Sample Gene Expression Profiles 1.0 1.52242 GTEX-Q734-0826-SM-48U1G GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 Posterior parietal association areas Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.80043 GSE148200_3_v_2_gemcitabine_human RummaGEO Drug Perturbation Signatures 1.0 null EGR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PIAS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78495 intermediate stratum of r7BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08412 intermediate stratum of m1AD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.34879 VZ in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.16495 GSE201309_1_v_0_matrine_human RummaGEO Drug Perturbation Signatures 1.0 null NCIH524 CCLE Cell Line Gene CNV Profiles 1.0 1.66217 GTEX-XGQ4-2026-SM-4AT6G GTEx Tissue Sample Gene Expression Profiles 1.0 0.891788 H3K4me3_fibroblast of the aortic adventitia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null laterorostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.74881 Rectum adenocarcinoma_READ_TCGA-EI-6884-01A-11R-1928-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TRMT10B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84624 HSFX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21444 MITF ChEA Transcription Factor Targets 1.0 null MAX_C2C12_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QXCU-0008-SM-48FCH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 MYC_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PAX6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.5581 UBTF_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-38-4630-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_cortical plate_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null fastigial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.5522 H3K4me3_MCF-7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CRX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6155 GTEX-OIZG-1326-SM-2HMIQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.60679 GSE229580_2_v_3_creb1_human RummaGEO Gene Perturbation Signatures 1.0 null Posterior parietal association areas, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43161 HCC2885 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.84374 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4822-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAFF ENCODE Transcription Factor Targets 1.0 null GSE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02416 GTEX-N7MS-0011-R6a-SM-2HMJ4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 EGR1-20690147-ERYTHROLEUKEMIA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Primary visual area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.98953 POLR2AphosphoS5_HL-60_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null rt1 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.64 Brain Lower Grade Glioma_LGG_TCGA-FG-6688-01A-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Entorhinal area, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25195 TFAP2C ChEA Transcription Factor Targets 1.0 null pyramidal layer of caudal subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.00518 PORCN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.02534 inner SZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.15656 LSM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46751 SYP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91323 A2780 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.877778 H3K9ac_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null superficial stratum of CCx (cortical plate/marginal zone) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03238 inferior olivary complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.12374 GSE123836_2_v_3_myf6_mouse RummaGEO Gene Perturbation Signatures -1.0 null TMEM248 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23288 HL60 CCLE Cell Line Gene Expression Profiles 1.0 1.67071 H3K4me3_BE2C_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null dorsal paracommissural tectal nucleus, m1 part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.45872 TAF7 ENCODE Transcription Factor Targets 1.0 null GTEX-U4B1-1626-SM-3DB8N GTEx Tissue Sample Gene Expression Profiles 1.0 1.30715 YY1_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_HepG2_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null CEBPD ENCODE Transcription Factor Targets 1.0 null GTEX-XLM4-1526-SM-4AT6D GTEx Tissue Sample Gene Expression Profiles 1.0 0.841567 H2AFZ_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K79me2_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QEG4-0126-SM-48TZE GTEx Tissue Sample Gene Expression Profiles 1.0 0.907503 Lung adenocarcinoma_LUAD_TCGA-05-4432-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-OXRO-0226-SM-3LK6F GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-WFON-2326-SM-3LK7M GTEx Tissue Sample Gene Expression Profiles 1.0 1.09294 BCLAF1 ENCODE Transcription Factor Targets 1.0 null TAF1_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-P4QR-0726-SM-2I5GO GTEx Tissue Sample Gene Expression Profiles 1.0 1.03824 H3K4me1_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null FOXA1 ENCODE Transcription Factor Targets 1.0 null striatum_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.59761 496100508_PCx_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.93916 H3K4me3_bronchial epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTF2F1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GABPA ENCODE Transcription Factor Targets 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_7732_KD_RRP6_SRP062389 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.47165 H2BC5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32958 TAF1_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null regulation of catalytic activity GO Biological Process Annotations 2015 1.0 null GTEX-XBEC-1326-SM-4AT69 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-PLZ6-0006-SM-33HBZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 Bed nuclei of the stria terminalis, anterior division, fusiform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12297 H3K4me3_SK-N-SH_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-U412-0326-SM-3DB9L GTEx Tissue Sample Gene Expression Profiles 1.0 1.09785 COLO 857 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.859906 K-562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.17565 PMC9248879-supp_gr.275831.121_Supplemental_Table_S2.xlsx-TP53-dependent_proteins-GeneName_TP53 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-RNOR-0008-SM-48FEY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A4BB-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsolateral prefrontal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.32394 HMGN3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SNMC-0426-SM-4DM5Y GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 USF2_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null organelle LOCATE Predicted Protein Localization Annotations 1.0 null SIMA DepMap CRISPR Gene Dependency 1.0 6.61166 GTEX-XQ3S-0126-SM-4BOO9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GSE169571_5_v_1_dexamethasone_mouse RummaGEO Drug Perturbation Signatures -1.0 null POLR2A_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A905-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CYB5D2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96507 ARID3A ENCODE Transcription Factor Targets 1.0 null RGL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74888 H3K4me3_fibroblast of skin of abdomen_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null SIN3A_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SIN3A_Panc1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of m1AD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.45524 GSE200352_11_v_6_pparg_mouse RummaGEO Gene Perturbation Signatures -1.0 null POLR2AphosphoS2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XV7Q-2126-SM-4BRVX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 molecular_function GO Molecular Function Annotations 2015 1.0 null MHH-ES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03038 RLN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55566 whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null ZXDB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3922 LRRC73 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12128 GTEX-PWCY-0826-SM-48TCR GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 striatum_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.861539 GTEX-OHPN-2726-SM-2I5H4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.70721 GSE146247_0_v_1_sirt7_human RummaGEO Gene Perturbation Signatures -1.0 null SG in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03037 GTEX-WEY5-0226-SM-3GIKN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 Perturb_11930_KO_RUNX1_SRP199099 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.93883 H3K4me3_foreskin fibroblast_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Type II spiral ganglion neuron_Brain_Mouse CellMarker Gene-Cell Type Associations 1.0 null dorsal motor nucleus of the vagus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.905844 Pancreatic adenocarcinoma_PAAD_TCGA-HV-A5A3-11A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27ac_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null posteroventral (inferior) parietal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.76078 MAX_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S3XE-1526-SM-4AD5A GTEx Tissue Sample Gene Expression Profiles 1.0 0.869919 GTEX-REY6-1326-SM-48FDO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 plant TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.578016 KASUMI1 CCLE Cell Line Gene Expression Profiles 1.0 1.57851 CCN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.74936 GTEX-Q2AG-0426-SM-2S1PU GTEx Tissue Sample Gene Expression Profiles 1.0 1.33198 GSE210101,GSE210114_0_v_3_urod_human RummaGEO Gene Perturbation Signatures -1.0 null H3K4me1_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null USF1_C2C12_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A49I-01A-12R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Retrosplenial area, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30623 H3K4me3_GM12878_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.78653 GTEX-OXRL-2626-SM-2I3F1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 HMX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30624 PAPLN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.44493 CYB561D2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99363 CACNB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86941 medial subdivision of central nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.06912 PREB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51965 OCLN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68416 periventricular stratum of m1AD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.40527 GTEX-XQ3S-0626-SM-4BOOB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 SNU685 CCLE Cell Line Gene Expression Profiles -1.0 -1.87477 GTEX-XYKS-2626-SM-4BRUT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GSE180951_1_v_4_bleomycin_mouse RummaGEO Drug Perturbation Signatures -1.0 null MON DepMap CRISPR Gene Dependency 1.0 4.31474 PRKCI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86037 frontal pole, right, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.54191 SLC25A34 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84461 ATP6V0E1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02748 H3K4me1_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-SIU8-0826-SM-2XCDQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.826263 protein phosphatase inhibitor activity GO Molecular Function Annotations 2015 1.0 null Lyf-1 MotifMap Predicted Transcription Factor Targets 1.0 null granular layer of rostral dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.847053 USF1_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null GSE227592_2_v_1_adar_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-PWOO-2326-SM-2S1PQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.47865 posteromedial visual area, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.45221 PXDN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46625 KAT5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04612 SRD5A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.0587 H2BK15ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-WH7G-2226-SM-3NMBN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 mantle zone of m1AD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.40422 GSE165636_0_v_4_tofacitinib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE152441,GSE152442_1_v_5_folic acid_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me1_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null SLC25A17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12559 Progressive myoclonus epilepsy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.392 GSS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0568 phosphatase inhibitor activity GO Molecular Function Annotations 2015 1.0 null JUND_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TTC31 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19004 POLR2AphosphoS5_Panc1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF76 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.9687 TUBB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.49798 TPRG1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.21875 primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.1232 hypoglossal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.74796 HCFC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-Kasumi-1-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_Kasumi-1_LYL1 Rummagene Transcription Factor Associations 2026 1.0 null POLR2A_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null VCX3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50396 GTEX-XUZC-0126-SM-4BOO6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 TSPYL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39278 TPGS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13199 SUPT16H CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76573 SNU-638 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.1667 GTEX-NFK9-1326-SM-3LK5I GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-XXEK-1026-SM-4BRUW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 Lingula (I), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18685 HCC1162 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.84374 MRPS12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55971 MRC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47498 NR2F2 ENCODE Transcription Factor Targets 1.0 null GTEX-PWOO-0008-SM-48TDU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 H3K9ac_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null DHX36 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56982 USF1_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null temporal pole, left, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.934093 SHOC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15622 dorsolateral prefrontal cortex_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.28389 GRPEL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.96692 H1-1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1114 GTEX-WRHU-0226-SM-3MJFV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 POLR2AphosphoS5_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null COLO 792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.971507 C11orf24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82446 dorsal subnucleus of MG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.44387 H3K4me3_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null DD-36-YH76_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.284432 A3/KAW Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.50224 POLR2A_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RTN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35405 mantle zone of r7BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.64798 H3K79me2_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Perturb_4489_KO_Rnu11/Trp53_SRP309496 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.44088 HNF4A ENCODE Transcription Factor Targets 1.0 null ZNF143_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null central nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GTEX-PSDG-0326-SM-48TCP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GABPA_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null REST_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_choroid plexus epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BRCA1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RARB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.1962 PMC8242083-41467_2021_24064_MOESM4_ESM.txt--HSF1_HSF1 Rummagene Transcription Factor Associations 2026 1.0 null SLC35D3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22101 abducens nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.898455 SP1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CILP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.68263 mantle zone of ERCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44614 Agranular insular area, dorsal part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.91649 TP53 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 47.7073 HDLM2 CCLE Cell Line Gene CNV Profiles -1.0 -2.20902 PBX3 ENCODE Transcription Factor Targets 1.0 null PMC8791933-41598_2022_4817_MOESM4_ESM.xlsx-PAX7_down-Unnamed_1_PAX7 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_SK-N-SH_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GATA3 ENCODE Transcription Factor Targets 1.0 null GTEX-P4PQ-0008-SM-48TDX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 496100491_HIP_no dementia_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.00836 POLR2A_spleen_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PBX3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null sublayer 6a of OCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25972 CTCF ENCODE Transcription Factor Targets 1.0 null trochlear nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.864867 ZC3H11A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WH7G-1926-SM-4LVMM GTEx Tissue Sample Gene Expression Profiles 1.0 0.828976 GTEX-S4Q7-0526-SM-4AD5N GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 hsa-miR-548d-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.598666 ALAS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.01487 OST4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42239 TMED9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85557 Colon - Sigmoid GTEx Tissue Gene Expression Profiles 2023 1.0 7.21149 RNF2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SHSY5Y DepMap CRISPR Gene Dependency 1.0 3.51056 ventral subnucleus of MG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.74544 H3K4me3_BJ_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_WI38_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-Q2AH-1926-SM-2S1PN GTEx Tissue Sample Gene Expression Profiles 1.0 0.844768 inner CP in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.37845 EZH2_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOS JASPAR Predicted Transcription Factor Targets 1.0 null GSE102132_2_v_1_irf3_human RummaGEO Gene Perturbation Signatures 1.0 null pituitary GTEx Tissue Gene Expression Profiles 1.0 1.06505 CEBPB JASPAR Predicted Transcription Factor Targets 1.0 null PTBP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.8022 hsa-miR-548b-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.598666 H3K4me3_fibroblast of skin of abdomen_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Anterior olfactory nucleus, external part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.35307 GTEX-WVLH-3126-SM-3MJGA GTEx Tissue Sample Gene Expression Profiles 1.0 0.997576 PAFAH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82456 PMC7452054-mmc1.docx-28-FOXG1_FOXG1 Rummagene Transcription Factor Associations 2026 1.0 null USF1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZBTB26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50547 frontal pole, left, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.23424 furan CTD Gene-Chemical Interactions 1.0 null GTEX-OXRN-1326-SM-3LK5V GTEx Tissue Sample Gene Expression Profiles 1.0 2.95895 layer VI of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.99589 TBP_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WOFL-0726-SM-3MJG4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.91833 N4BP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29388 Retrosplenial area, dorsal part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28645 Lung squamous cell carcinoma_LUSC_TCGA-85-A4QR-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE136627_3_v_1_hdac4_mouse RummaGEO Gene Perturbation Signatures -1.0 null salivary gland GTEx Tissue Gene Expression Profiles 1.0 1.02571 Cortical amygdalar area, posterior part, medial zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04364 H3K4me3_foreskin fibroblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-TSE9-0526-SM-3DB7Z GTEx Tissue Sample Gene Expression Profiles 1.0 1.05543 RCOR1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r2 part of principal trigeminal sensory nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.54655 TP53-23651856-MEF-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null H3K36me3_CH12.LX_mm9_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF503 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.98105 OV56 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.874123 PMC9941047-41591_2022_2163_MOESM3_ESM.xlsx-ST12-Unnamed_1_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null Piriform-amygdalar area, polymorph layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14249 MAFK ENCODE Transcription Factor Targets 1.0 null LCLC-103H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.937597 ELF1 ENCODE Transcription Factor Targets 1.0 null Perturb_18554_KD_miR466c_SRP319883 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 6.10462 INTS13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.20359 THTPA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6788 GTEX-XBEW-0006-SM-4AT4E GTEx Tissue Sample Gene Expression Profiles 1.0 0.878718 BHLHE40 ENCODE Transcription Factor Targets 1.0 null CUX1 ENCODE Transcription Factor Targets 1.0 null SREBF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.9112 GTEX-S4Q7-1326-SM-4AD74 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-Q2AI-1226-SM-48U14 GTEx Tissue Sample Gene Expression Profiles 1.0 0.897744 C170 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.889039 primary auditory cortex (core)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.00178 GTEX-WOFM-1726-SM-3MJFA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 PANC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.41938 H3K4me1_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RCOR1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S4Q7-1526-SM-3K2AG GTEx Tissue Sample Gene Expression Profiles 1.0 1.76167 Lassa Fever Virus_8hr_24069471_GSE41300 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -4.15492 Prostate adenocarcinoma_PRAD_TCGA-HI-7169-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KMS12BM CCLE Cell Line Gene CNV Profiles -1.0 -1.79444 outer CP in (rostral) midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.139 MAX_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A5U2-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-VW-A7QS-01A-12R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4779 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 MMACHC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42631 USF2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SIU7-0926-SM-4BRX1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-QVUS-0226-SM-3GIJY GTEx Tissue Sample Gene Expression Profiles 1.0 0.999996 POLR2AphosphoS5_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null UBE3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28077 frontal operculum, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.03747 POLR2A_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHP212 CCLE Cell Line Gene CNV Profiles 1.0 2.41982 UBTF ENCODE Transcription Factor Targets 1.0 null ABCD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.73351 SK-UT-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null MOLT-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null RBBP5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FMO5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.86776 ZNF559 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51874 JADE2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.70116 H3K4me3_endothelial cell of umbilical vein_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null NFE2 ENCODE Transcription Factor Targets 1.0 null GSE201309_4_v_8_matrine_human RummaGEO Drug Perturbation Signatures -1.0 null H3K4me3_kidney epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null ATF3_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAF1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_HGPS cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TEAD4_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXA2 ChEA Transcription Factor Targets 1.0 null ZNF542P CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.73681 TMEM123 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73636 GTEX-R55E-0726-SM-48FCZ GTEx Tissue Sample Gene Expression Profiles 1.0 0.833493 ZNF528 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60452 MZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.23183 MAFG::NFE2L1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.3048 III, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.07041 GTEX-T6MN-2026-SM-4DM7L GTEx Tissue Sample Gene Expression Profiles 1.0 0.842822 POLR2A_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null REST_neural cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MITF-21258399-MELANOMA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null PNPLA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14675 TCF7L2 ENCODE Transcription Factor Targets 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-37-A5EN-01A-21R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9ac_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CP in rostral hippocampus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.49141 H3K4me1_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2AphosphoS5_PFSK-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Anteromedial visual area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09078 ITM2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31665 CEBPB_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KYSE520 CCLE Cell Line Gene CNV Profiles -1.0 -1.51683 SNU213 CCLE Cell Line Gene Expression Profiles -1.0 -1.5417 GTEX-T2IS-2226-SM-4DM65 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 r3 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06907 H3K4me2_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_13484_KO_Bmal1_SRP260650 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 8.25025 H3K4me3_BE2C_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QDVJ-1926-SM-2S1PJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.76271 Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HG-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.12061 FOXA1_T47D_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ASCL5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03841 POLR2AphosphoS2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null USF1_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MZ in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.918907 GTEX-N7MT-0011-R10A-SM-2I3E1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 ABI2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.63373 JUN JASPAR Predicted Transcription Factor Targets 1.0 null Multiple epiphyseal dysplasia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.687 H3K27ac_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null USF2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ARMC10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98147 HCT 116 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.3733 CACNB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78769 GTEX-R55G-0008-SM-48FEX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GSE238018_1_v_0_mxra8_human RummaGEO Gene Perturbation Signatures 1.0 null ATF3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X5EB-2326-SM-46MW5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.20115 Posterior parietal association areas, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30675 GABPA_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null prostate HPA Tissue Gene Expression Profiles 1.0 1.13993 GSE152937_12_v_1_slc16a13_mouse RummaGEO Gene Perturbation Signatures -1.0 null paraventricular nucleus of hypothalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.16127 GTEX-OIZH-1626-SM-2HMKI GTEx Tissue Sample Gene Expression Profiles 1.0 1.39599 ZNF200 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56968 HCC1576 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.17137 GTEX-O5YT-1426-SM-3MJHC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 H3K27ac_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XLM4-0011-R7A-SM-4AT5L GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 TRIM37 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13154 GSE135350_3_v_1_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null JHOS2 CCLE Cell Line Gene CNV Profiles 1.0 1.5202 CHURC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65349 ARL4C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62396 Liver hepatocellular carcinoma_LIHC_TCGA-ZS-A9CF-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_7764_KD_RRP40_SRP062389 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 18.8539 SAP30 ENCODE Transcription Factor Targets 1.0 null primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.990317 EZH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21987 NOTO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27484 Primary somatosensory area, trunk, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18272 SLC25A35 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.82524 GTEX-XUZC-2126-SM-4BRW8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.88074 GTEX-S3XE-1226-SM-4AD4L GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 r4 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.90997 BHLHE40_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null COLO 680N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20756 CTCF_bone marrow macrophage_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAZ_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF770 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.6438 H3K4me3_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CSTF2T CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05404 Colorectum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 KLF17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5716 TCF3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R55E-0006-SM-2TC5G GTEx Tissue Sample Gene Expression Profiles 1.0 1.01244 H3K4me3_fibroblast of pulmonary artery_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null FOSL2_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAF1_neural cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE195663_0_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null FAM131A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47949 CSNK1E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50465 DEDD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66932 TBC1D16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32665 NCIH727 CCLE Cell Line Gene Expression Profiles -1.0 -1.48008 GTEX-NPJ8-1426-SM-3MJHR GTEx Tissue Sample Gene Expression Profiles 1.0 0.824547 ABHD8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90799 basal nucleus of meynert, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.875816 NCI-H1975 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.36566 COG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01352 Perturb_13620_KD_Ddr2_SRP350312 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.50095 GTEX-WEY5-1126-SM-4LMIE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 Perturb_8953_Mut_RB1_SRP220467 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 POLR2A_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAF1_neural cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PALM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17928 OCIAML5 CCLE Cell Line Gene Expression Profiles 1.0 1.91 POLR2AphosphoS5_neural cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Intergeniculate leaflet of the lateral geniculate complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24889 GTEX-R53T-1526-SM-48FEK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 NCIH522 DepMap CRISPR Gene Dependency 1.0 2.15397 POLR2A_A549_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QEG5-1226-SM-447AR GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 496100287_TCx_no dementia_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.01059 GTEX-WHPG-2326-SM-3NMBP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 Main olfactory bulb, mitral layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06047 MTA3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SPINDOC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78715 GTEX-X261-0326-SM-3NMD4 GTEx Tissue Sample Gene Expression Profiles 1.0 2.39689 SP4_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100505_TCx_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.00941 RWDD2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45785 ZBTB7A_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOSL1 ENCODE Transcription Factor Targets 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A895-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-SE5C-0426-SM-4BRUI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 ATP8B2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61696 ANGPTL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34399 TP53INP2_OE_GDS5054_385_mouse_Muscle GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GTEX-XOTO-0526-SM-4B662 GTEx Tissue Sample Gene Expression Profiles 1.0 2.24643 GSE110268_1_v_3_foxd1_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K27ac_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K79me2_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SZ in subgenual cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.50041 GSE132408_0_v_3_tet2_human RummaGEO Gene Perturbation Signatures 1.0 null SCC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.41321 TAF1_PFSK-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RU72-0008-SM-46MV8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 NCI-H1915 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.85318 TNFRSF10A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.98354 RNF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.81902 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4983-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null layer 5 of CCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22366 MXI1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null periventricular mantle of isBM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03274 EA-18-FP00_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.240762 USF1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1355 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.943634 BAZ1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55682 NR2F2_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SF3A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00917 NR2C2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.205 GTEX-X5EB-0626-SM-46MVQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 EFO-27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.59163 frontal pole, right, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.45046 POLR2AphosphoS5_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CALU-6 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07451 hsa-miR-3178 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 hsa-miR-27a TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 YY1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RCE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.47132 HOP-62 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.09062 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4642-01B-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BTBD6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47552 H3K4me3_myocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2AphosphoS5_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R55F-0005-SM-2TF4W GTEx Tissue Sample Gene Expression Profiles 1.0 0.996947 HA-E2F1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null skeletal muscle HPA Tissue Gene Expression Profiles 1.0 2.24522 USP28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.07256 TE8 CCLE Cell Line Gene Expression Profiles -1.0 -1.58211 DTD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61969 TSHZ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42932 hsa-miR-548c-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.632343 ARHGEF39 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79003 KDM3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.32211 CAPRIN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06757 JAZF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90463 POLR2A_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ELP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.13294 GTEX-NPJ8-2426-SM-3MJHL GTEx Tissue Sample Gene Expression Profiles 1.0 0.988983 G118 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.13196 insular cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06264 GPD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22996 POLR2AphosphoS5_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.986037 GSE157296,GSE157298_4_v_5_kbtbd4_human RummaGEO Gene Perturbation Signatures -1.0 null ELK1 ENCODE Transcription Factor Targets 1.0 null OCIAML2 CCLE Cell Line Gene Expression Profiles 1.0 2.73577 GTEX-WL46-0011-R5A-SM-3LK6V GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L7-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-60-2726-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE146982_3_v_6_gpd1_human RummaGEO Gene Perturbation Signatures -1.0 null ARC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.61748 SMC3_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NR2F2_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HDAC2 ENCODE Transcription Factor Targets 1.0 null YPEL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10176 H3K4me2_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NCOA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5654 GTEX-N7MS-0426-SM-2YUN6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.73176 TBX18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68199 H3K27ac_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_SK-N-MC_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null HMGN3 ENCODE Transcription Factor Targets 1.0 null GTEX-WRHK-0826-SM-3MJFG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-OHPK-1626-SM-2YUN3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.37273 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1A7-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventrolateral prefrontal cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.990697 Hair follicle inner root sheath TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.6 BAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66013 TEAD4_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intermediate part of r3B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06907 SMURF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79293 SLC25A24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.49448 H3K4me3_K562_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null TBX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.5546 MFSD14A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41678 MAPK8IP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.90122 H3K4me1_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null motor nucleus of trigeminal nerve, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.31855 GTEX-QDVN-0226-SM-48TZ9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 Perturb_2419_KD_DDX3X_ERP105312 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.39632 PHF8 ENCODE Transcription Factor Targets 1.0 null Perturb_765_KD_ZFR_SRP107875 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.1591 FUBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87164 GTEX-X585-0011-R3B-SM-46MVG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 REST_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CBX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55518 Lung squamous cell carcinoma_LUSC_TCGA-85-8070-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HNF4A_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZFP36L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.28271 CHD2 ENCODE Transcription Factor Targets 1.0 null intermediate stratum of r7BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55422 POLR2A_GM18526_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-REY6-0126-SM-48FDT GTEx Tissue Sample Gene Expression Profiles 1.0 0.89516 Primary visual area, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.85863 dorsolateral prefrontal cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.943571 Rarb JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 59.2576 HS 766T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.935633 SKUT1 DepMap CRISPR Gene Dependency 1.0 4.73173 GTEX-V1D1-2426-SM-3GAER GTEx Tissue Sample Gene Expression Profiles 1.0 1.62474 GSE133329_2_v_3_trim28_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-REY6-0926-SM-48FDA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GSE182680,GSE182683_0_v_4_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null GSE212330_1_v_0_azacitidine_human RummaGEO Drug Perturbation Signatures 1.0 null CREBRF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96022 GTEX-Q2AH-0526-SM-2I3ED GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-OIZG-0226-SM-2TC5L GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-P4PQ-1626-SM-2HMKK GTEx Tissue Sample Gene Expression Profiles 1.0 1.49656 Partial androgen insensitivity syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.282 Cortical amygdalar area, posterior part, medial zone, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27834 FIGLA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.3834 H3K4me3_Jurkat_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null JUND_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NFKB1 JASPAR Predicted Transcription Factor Targets 1.0 null TNFRSF21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46944 GTEX-OXRP-2326-SM-2S1NL GTEx Tissue Sample Gene Expression Profiles 1.0 1.38326 H3K27ac_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SPRN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90691 CPNE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.786 GSE234340_4_v_7_muc2_mouse RummaGEO Gene Perturbation Signatures 1.0 null SMAD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07061 GTEX-QXCU-1726-SM-2TC6L GTEx Tissue Sample Gene Expression Profiles 1.0 1.14398 Acute Myeloid Leukemia_LAML_TCGA-AB-2832-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null YMB1 CCLE Cell Line Gene Expression Profiles 1.0 1.44183 SIX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48475 GTEX-T2IS-2626-SM-32QPP GTEx Tissue Sample Gene Expression Profiles 1.0 1.24731 PML_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ventral tier of thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.61496 HCC2218 CCLE Cell Line Gene Expression Profiles 1.0 1.48923 emboliform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.48526 PAX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24687 GSE169571_0_v_2_dexamethasone_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE155695,GSE155696_1_v_0_acetaminophen_mouse RummaGEO Drug Perturbation Signatures 1.0 null CHD1 ENCODE Transcription Factor Targets 1.0 null VWA5A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.81596 TPP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09136 posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.27088 GTEX-Q734-1426-SM-48TZQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 NCI-H23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.88757 H3K4me1_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-PVOW-2726-SM-48TCA GTEx Tissue Sample Gene Expression Profiles 1.0 0.980423 GTEX-U8T8-1126-SM-4DXUE GTEx Tissue Sample Gene Expression Profiles 1.0 0.887407 OVKATE CCLE Cell Line Gene CNV Profiles 1.0 1.74739 Perturb_11931_KO_STAG2_SRP199099 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 CBX7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87273 E2F4_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FIZ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.86609 USP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54086 ZNF143_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QVUS-0011-R4A-SM-3GAE7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 MM160113 DepMap CRISPR Gene Dependency 1.0 2.11506 MOR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.935633 GTEX-P44H-0008-SM-48TDW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 DAZAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63255 midbrain reticular formation, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.69075 GSE152937_12_v_7_slc16a13_mouse RummaGEO Gene Perturbation Signatures -1.0 null MAX_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R55E-0011-R7A-SM-2TC5Z GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GATA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.9765 H3K4me3_GM12866_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ELF1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ATF3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_B cell_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null CPC-N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.23533 H3K4me3_keratinocyte_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WL46-0011-R3A-SM-3TW8E GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-S4UY-0526-SM-3K2AN GTEx Tissue Sample Gene Expression Profiles 1.0 1.16951 Perturb_8956_KO_RB1_SRP220467 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 HN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.64658 EEF1AKMT4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.73797 SKMEL5 CCLE Cell Line Gene CNV Profiles 1.0 1.61447 IRGQ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5634 NCI-H1930 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.87511 HMY-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.36566 KIF5C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.046 HOXA5 JASPAR Predicted Transcription Factor Targets 1.0 null GTEX-OOBK-2626-SM-2HMKY GTEx Tissue Sample Gene Expression Profiles 1.0 0.888361 SNU685 CCLE Cell Line Gene CNV Profiles 1.0 1.65503 A3/KAW Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26642 BC-40-TU13_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.315187 NR2F2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OVCAR433 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07299 HIC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.13165 CHD1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOSL1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SK-MEL-5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.21867 Scd1_DELETION_GDS4910_309_mouse_Skin GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null RCN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00088 USF1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RXRA::VDR JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.6 PSMF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27159 globose nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.84366 RNASE7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59858 CENPF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05055 OCIMY5 CCLE Cell Line Gene CNV Profiles -1.0 -2.13127 VMRCLCD CCLE Cell Line Gene Expression Profiles -1.0 -2.85243 MXI1 ENCODE Transcription Factor Targets 1.0 null HOXB4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02798 Foxn1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 14.6938 ADPRH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.63399 TTLL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.03314 SLC29A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92973 POLR2A_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZMIZ1 ENCODE Transcription Factor Targets 1.0 null fallopian tube GTEx Tissue Gene Expression Profiles -1.0 -1.34311 GTEX-T5JW-0926-SM-4DM5K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 ZFTRAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89925 RUNX3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SK-N-SH Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07699 GTEX-U3ZM-1226-SM-3DB9G GTEx Tissue Sample Gene Expression Profiles 1.0 1.3042 MAGEH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.94386 GSE234340_1_v_7_muc2_mouse RummaGEO Gene Perturbation Signatures 1.0 null orbital frontal cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.13081 superficial layers of olfactory entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.900794 GTEX-QLQ7-0826-SM-447B3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 H3K4me3_Caco-2_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-T5JC-1226-SM-4DM7C GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 ABCA7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12008 GTEX-WL46-0011-R2A-SM-3LK6O GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 RFX5_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HSBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85116 PMC10591418-12711_2023_849_MOESM11_ESM.xls-AA_1W_vs_LS_1W-gene_name_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null TAF7_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RNOR-2226-SM-2TF5O GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 magnocellular (medial) division of MD Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.11582 Perturb_14173_KO_HOXBLINC_SRP149346 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.84956 oculomotor nucleus, main part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15517 KARPAS-45 COSMIC Cell Line Gene Mutation Profiles 1.0 null Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null M059K Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.38013 TNFRSF10B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8212 SCC9 CCLE Cell Line Gene CNV Profiles 1.0 1.49494 CNR_KO_GDS2820_636_mouse_Skin GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null SK-MEL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.27222 Accessory olfactory bulb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.53683 CTV1DM DepMap CRISPR Gene Dependency 1.0 2.63285 Lung squamous cell carcinoma_LUSC_TCGA-L3-A524-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TAF1_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Gfi1b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.477 POLR2A_small intestine_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC4856960-supp_gkv1471_nar-01762-z-2015-File010.xls-Genes_5kb_E2F7_Hyp-gene_name_E2F7 Rummagene Transcription Factor Associations 2026 1.0 null DIFI DepMap CRISPR Gene Dependency 1.0 2.20934 FKBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61221 MAPK12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61914 KARPAS-1106P Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.17565 GSE123689_1_v_0_cbx8_human RummaGEO Gene Perturbation Signatures -1.0 null MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07299 G140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.880778 RAD21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9756 HT-29 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.886181 GSE179693,GSE179694_4_v_2_panobinostat_human RummaGEO Drug Perturbation Signatures -1.0 null regulation of hydrolase activity GO Biological Process Annotations 2015 1.0 null H3K4me3_epithelial cell of esophagus_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SPOPL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.49971 GTEX-XXEK-2526-SM-4BRUR GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 TP53INP2_OE_GDS5053_312_mouse_Skeletal muscle GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null CTCF_spleen_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ATP11A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41444 CTCF_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HEC-1-A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07971 MCAM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19022 HNF4A ChEA Transcription Factor Targets 1.0 null POLR2A_K562_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null GABPA_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE68925_1_v_0_fasudil_human RummaGEO Drug Perturbation Signatures 1.0 null ZNF526 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69173 IZ in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.05205 SF539 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.03861 SIGM5 CCLE Cell Line Gene Expression Profiles 1.0 2.78974 H3K4me3_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K9ac_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-O5YV-2026-SM-2D7VS GTEx Tissue Sample Gene Expression Profiles 1.0 1.20826 Plagl1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 30.8082 H3K4me3_fibroblast of foreskin _hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CAVIN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13457 Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0EZ-01A-21R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCDN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64315 HEP G2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.943634 YY1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R53T-1326-SM-48FCQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 IV, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.837139 hsa-miR-548w TargetScan Predicted Conserved microRNA Targets 1.0 0.632343 JHOM2B CCLE Cell Line Gene CNV Profiles -1.0 -2.26969 NBPF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9475 deep white layer of SC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14173 GTEX-WHSB-1626-SM-3LK6J GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-WK11-2526-SM-3NM9Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.12182 BICR 31 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.874123 PMC12396377-jcb_202307079_tables1.xlsx-Fig_1C_i_-_iii_right-x_TFEB_KOcon_VS_WTcon_UP_TFEB Rummagene Transcription Factor Associations 2026 1.0 null MAX_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TEAD4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.99 BCL11A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.4947 KATO III Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.971513 GTEX-VUSG-2626-SM-4KKZI GTEx Tissue Sample Gene Expression Profiles 1.0 1.10511 TBP_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MTERF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.07512 SMSCTR DepMap CRISPR Gene Dependency 1.0 3.86567 SVBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72303 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YJ-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE229914_1_v_3_keap1_human RummaGEO Gene Perturbation Signatures 1.0 null GSE103068_5_v_7_volasertib_human RummaGEO Drug Perturbation Signatures -1.0 null USF2 ENCODE Transcription Factor Targets 1.0 null CHD1_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_kidney_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC5263239-mmc2.xls-MV4_11_-_MLL-AF4-Non-spreading_targets_gene_names_1985_unique_KMT2A Rummagene Transcription Factor Associations 2026 1.0 null SNAPC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16118 GABPA_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K79me2_MEL cell line_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TAF1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null DNMT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65812 TCF12_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null USF1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null USF1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CEBPB ENCODE Transcription Factor Targets 1.0 null KASUMI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.41321 RBBP5_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TCF12_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null anterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.19965 WRAP73 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49276 ROCK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39457 POU2F2_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null layer 1 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19726 MYC_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_cardiac fibroblast_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null ZNF800 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92847 SP1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X5EB-1026-SM-46MVU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 USF2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC5903287-NIHMS956886-supplement-Table_2.xls-THP1_THP2_cds_exp_up-gene_GLI2 Rummagene Transcription Factor Associations 2026 1.0 null Hair follicle bulge TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.541 ING1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61736 MYC_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null ZNF384 ENCODE Transcription Factor Targets 1.0 null GTEX-XQ8I-0126-SM-4BOPL GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 POLR2AphosphoS2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R53T-0008-SM-48FEW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-V955-2426-SM-3GAEF GTEx Tissue Sample Gene Expression Profiles 1.0 1.22911 MZ in caudal cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.28548 GTEX-PWN1-1626-SM-2S1OL GTEx Tissue Sample Gene Expression Profiles 1.0 1.35678 H3K4me3_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null THAP1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null intermediate stratum of r6BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05457 ZNF823 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69841 IFT122 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81043 PLBD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6722 superficial layers of caudal presubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.05757 Multiple epiphyseal dysplasia 1 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.3 Entorhinal area, lateral part, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.84948 SH2B2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82362 H3K4me3_NB4_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SATB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5345 r7 part of paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.78584 DDX27 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.76455 UBE2Q2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40836 H3K4me3_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CCDC134 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91011 Whole body TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 MKN-74 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.826341 cell part LOCATE Predicted Protein Localization Annotations 1.0 null GTF2F1 ENCODE Transcription Factor Targets 1.0 null BHLHE40_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null IGHMBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96307 ADSS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74564 GSE103068_5_v_4_volasertib_human RummaGEO Drug Perturbation Signatures -1.0 null U-937 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00399 GTEX-R55D-1226-SM-48FE9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 KEAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08859 Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5560-01A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27ac_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-597 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 ATP8B3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32327 ELK1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Parapyramidal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.26579 TAF1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100418_TCx_no dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.3455 FOXF2 JASPAR Predicted Transcription Factor Targets 1.0 null GTEX-X62O-0008-SM-46MU5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 STAT3_MCF 10A_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-WN-A9G9-01A-12R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ABHD16B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.69046 TAF1_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null thp1 HPA Cell Line Gene Expression Profiles 1.0 1.91921 TP53INP2_OE_GDS5054_545_mouse_skeletal muscle GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null posteroventral (inferior) parietal cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.06315 GSE217776,GSE217829_2_v_6_sgf29_human RummaGEO Gene Perturbation Signatures -1.0 null Primary somatosensory area, trunk, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47731 pretectal nuclear complex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.867879 CTDSPL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93333 Magnocellular reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41258 H3K27ac_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE185519_1_v_2_gilteritinib_human RummaGEO Drug Perturbation Signatures -1.0 null EXTL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34479 HCC202 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.21867 GTEX-WYVS-2326-SM-3NMAI GTEx Tissue Sample Gene Expression Profiles 1.0 1.22315 H3K27ac_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SCYL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07263 MAZ ENCODE Transcription Factor Targets 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2861-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Parasubiculum, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24197 PAX5_GM12892_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.03119 POLR2A_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null AASDH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95252 Superior colliculus, motor related, deep white layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32811 GTEX-WHSB-1826-SM-3TW8M GTEx Tissue Sample Gene Expression Profiles 1.0 1.38587 GSE154577_2_v_12_plagl1_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-S7SE-0226-SM-2XCD4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 hsa-miR-3192 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 HCC202 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16382 COL9A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44012 PIP4P2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.44643 LEO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.43212 Perturb_10353_KO_Hbb_SRP333852 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.1863 H3K4me3_epithelial cell of esophagus_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CXCL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52706 Primary somatosensory area, trunk, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36722 Basomedial amygdalar nucleus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19726 H3K4me2_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_lung_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE178907_4_v_3_fkrp_human RummaGEO Gene Perturbation Signatures 1.0 null Sto TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.542 ZBTB33_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GOLT1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59797 Perturb_16393_KO_Barx2_SRP034552 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 DNAAF5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65061 mantle zone of r7BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3463 GTF3C2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27904 layer 1 of ERCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30675 ZBTB7A_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_HCT116_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TBP_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SS18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.26742 GSE206093,GSE206094_1_v_3_isl1_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_endothelial cell of umbilical vein_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null NCI-H1975 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.848766 H3K36me3_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BACH1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PPP1CA Pathway Commons Protein-Protein Interactions 1.0 null GTEX-PWOO-1226-SM-48TCO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 TUBB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77131 NUGC-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.84374 GTEX-R53T-1826-SM-3GIJX GTEx Tissue Sample Gene Expression Profiles 1.0 1.34582 ZBTB9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26647 CNIH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9102 H2AFZ_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF843 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1833 Rectum adenocarcinoma_READ_TCGA-DC-6155-01A-11R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FAAH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20576 PSMB8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7255 CDK2_knockdown_146_GSE31912 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.24805 SYN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22533 NOMO1 CCLE Cell Line Gene Expression Profiles 1.0 1.75451 anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.52191 TRIM71 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16946 DPH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.94223 GTF2A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04013 STAT1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-UTHO-0726-SM-3GAEN GTEx Tissue Sample Gene Expression Profiles 1.0 1.0824 MTFR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65547 MAX_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null layer 6 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02337 EHD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90618 CDCA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50633 r6 part of paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.6007 H3K4me3_cardiac mesoderm_hg19_7 ENCODE Histone Modification Site Profiles 1.0 null POLR2AphosphoS5_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SGO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80324 SLC2A8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95496 GTEX-XMD3-0006-SM-4AT5X GTEx Tissue Sample Gene Expression Profiles 1.0 1.0435 POLR2A_GM10847_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null COPS4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.15546 H2AFZ_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intermediate tier of thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1405 CREB1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PSMD9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11357 GSE131798,GSE131804_1_v_0_igf1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GAS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31537 GTEX-PX3G-1426-SM-48U1J GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-S3XE-1026-SM-4AD4O GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 SLC25A38 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80449 FNDC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88077 periventricular stratum of CoPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43436 ELF1_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null AXIN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.41821 GTEX-XPT6-2026-SM-4B64V GTEx Tissue Sample Gene Expression Profiles 1.0 1.66506 CHP212 DepMap CRISPR Gene Dependency 1.0 5.62883 CHD2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SLC24A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41991 GTEX-QDT8-0326-SM-32PL1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 Entorhinal area, lateral part, layer 2a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.61221 OVCA420 DepMap CRISPR Gene Dependency 1.0 7.01838 MXI1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null skeletal system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 IRX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32525 H3K27ac_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-S33H-2426-SM-2XCB2 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 external part of AOD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05423 RFX5_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-TKQ1-0926-SM-4DXU2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.828203 POLR2A_liver_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TEAD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.1049 POLR2A_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHAMP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44451 MYC_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cuneus, right, peristriate Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.05216 GSE133070_2_v_4_prss1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-WEY5-1926-SM-3GIL8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 COCH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98995 GTEX-WZTO-0011-R3B-SM-3NMC6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-R3RS-0526-SM-3GADG GTEx Tissue Sample Gene Expression Profiles 1.0 1.77208 HCC1187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.571 GTEX-REY6-2426-SM-48FF5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 TCF12_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.876473 PAX5_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_H54_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTSK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.03232 GTEX-X585-0011-R8A-SM-46MUX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 primary auditory cortex (core)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.898382 CREB1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_SK-N-MC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NDUFA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.40347 H2AFZ_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYC_MCF-7_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE133516_5_v_2_kat7_human RummaGEO Gene Perturbation Signatures 1.0 null TFB2M CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82784 hsa-miR-548a-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.670641 USF1_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC8995879-Table_1.xlsx-exome_variants_MAF_0_01-Gencode_34_hugoSymbol_MAF Rummagene Transcription Factor Associations 2026 1.0 null GTEX-XMD3-0008-SM-4AT4V GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 ELK1::SREBF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.9766 CHD1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QDVN-2426-SM-2S1Q4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.14944 Lung adenocarcinoma_LUAD_TCGA-55-8620-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_epithelial cell of proximal tubule_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-Q2AH-1826-SM-2S1Q2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.61342 ERLIN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.90523 E2F6_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1437 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.31945 DLG4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.35561 TAF1 ENCODE Transcription Factor Targets 1.0 null orbital frontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.921884 GSE131649_2_v_0_hemin_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-WRHK-1626-SM-3MJFH GTEx Tissue Sample Gene Expression Profiles 1.0 1.06996 TEAD1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.1221 H3K4me1_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null appendix HPA Tissue Protein Expression Profiles -1.0 -0.738732 NCIH647 CCLE Cell Line Gene CNV Profiles -1.0 -1.94593 GTEX-XYKS-2726-SM-4E3IC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 Perturb_8950_Mut_RB1_SRP220467 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 16.7462 TLK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98719 ABHD17B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.77244 H3K4me3_erythroblast_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null CEBPB_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Superior colliculus, motor related, deep gray layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13769 496100292_PCx_no dementia_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.65643 GTEX-T5JC-0526-SM-32PM7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 PMC11647701-JHA2-5-1243-s008.xlsx-RUNX1-Gene_Name_RUNX1 Rummagene Transcription Factor Associations 2026 1.0 null CHD2_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JUND_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null BHLHE40 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.6633 GTEX-T8EM-0006-SM-3DB71 GTEx Tissue Sample Gene Expression Profiles 1.0 0.940274 FAM199X CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16893 THAP1 ENCODE Transcription Factor Targets 1.0 null SFXN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85499 HCC78 DepMap CRISPR Gene Dependency 1.0 2.85881 Nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 SK-N-DZ Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.836662 GTEX-QDT8-0008-SM-48U2F GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-Q2AH-1526-SM-48TZG GTEx Tissue Sample Gene Expression Profiles 1.0 0.836339 YY1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null USF1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PRDM5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51693 SCML2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61818 H3K4me1_CH12.LX_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null DNAJB9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60007 H3K4me3_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null mRNA_SUZ12_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null H3K4me3_Panc1_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null JIYOYE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.844646 Hair follicle outer root sheath TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.745 IFT20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53266 KP4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.987541 DSEL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.63828 Nucleus x Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24682 MZ in rostral midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.14219 H3K4me3_A549_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null periventricular stratum of TG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3821 hippocampus (hippocampal formation)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.836443 H3K4me3_mammary epithelial cell_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GABPA_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R55E-0008-SM-48FCG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 MYOD1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.3432 cingulate gyrus, parietal part, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.935495 POLR2A_HepG2_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null EP300_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_MEL cell line_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WL46-0326-SM-3LK6Y GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 Acute Myeloid Leukemia_LAML_TCGA-AB-2910-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-T6MO-0626-SM-4DM6P GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-WXYG-2526-SM-3NB3F GTEx Tissue Sample Gene Expression Profiles 1.0 2.04843 GTEX-R55D-0008-SM-48FEV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 Perturb_13999_KD_MIR1271_SRP256886 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 12.4172 Perturb_13478_KO_GPR174_SRP400800 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 NFIC_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100423_PCx_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.49356 EGR1 ENCODE Transcription Factor Targets 1.0 null DACT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15857 NCI-H1651 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.5665 POLR2A_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X4XX-0008-SM-46MVK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 ZR-75-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.911736 GSE152937_6_v_5_slc16a13_mouse RummaGEO Gene Perturbation Signatures 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-A7CX-01A-12R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RMG-I Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03319 MAX_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EGR1_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null WSU-NHL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.49864 GSE199204,GSE211619_4_v_2_glutamine_human RummaGEO Drug Perturbation Signatures -1.0 null pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null ARID3A_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F2-06A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null WTAP_KD_GDS2010_69_human_HUVEC (umbilical vein endothelial cells) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-NB4-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_NB4_LYL1 Rummagene Transcription Factor Associations 2026 1.0 null TBP_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null layer 6 of OCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46454 BCLAF1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null AGXT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47511 PRKCSH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78487 H3K4me1_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_GM12892_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null FLOT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.06219 VMRCLCP CCLE Cell Line Gene CNV Profiles 1.0 1.40293 HCFC1_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OXRL-1626-SM-2YUMU GTEx Tissue Sample Gene Expression Profiles 1.0 1.49927 hsa-miR-548h TargetScan Predicted Conserved microRNA Targets 1.0 0.632343 TRIM47 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21098 UKE-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.829056 Chanarin-Dorfman syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.002 SIN3A_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null choroid plexus of the fourth ventricle Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.01297 MEST CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44312 PMC11749115-loae020_suppl_Supplementary_Table_S2.xlsx-CHOP-high-gene_DDIT3 Rummagene Transcription Factor Associations 2026 1.0 null GSE217776,GSE217829_1_v_6_sgf29_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-RM2N-1626-SM-2TF5N GTEx Tissue Sample Gene Expression Profiles 1.0 1.04555 H3K4me3_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HCC1319 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20756 ESR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.65575 PBX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.4744 APOBEC3G CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.89653 GTEX-T6MO-0006-SM-32QOU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 USF1_A549_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Ankyrin repeat-containing domain InterPro Predicted Protein Domain Annotations 1.0 null BTF3L4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20399 KIF26A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.1466 SLC22A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74698 Brain Lower Grade Glioma_LGG_TCGA-DU-A5TS-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-UJMC-1826-SM-3GADT GTEx Tissue Sample Gene Expression Profiles 1.0 1.89472 prepositus hypoglossal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.04515 HCC2885 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.14426 GTEX-REY6-0626-SM-2TF4G GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 H3K4me3_fibroblast of mammary gland_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null FOSL2::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.6967 MAFA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4742 muscle GTEx Tissue Gene Expression Profiles 1.0 2.18987 TCF7L2_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PLZ4-0926-SM-2S1OI GTEx Tissue Sample Gene Expression Profiles 1.0 1.01994 C3A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.06543 MYC_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF251 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.48074 GTEX-PWN1-0726-SM-48TDR GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 ISCA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44585 H3K36me3_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_CD14-positive monocyte_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null HDAC2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null orbital frontal cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.90578 PA-TU-8988S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.0071 Tcf12 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 34.1987 POLR2A_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CEP131 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20703 ZNF512B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60523 G44 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.83617 GTEX-WZTO-3026-SM-3NMA2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.952531 GTEX-QCQG-0326-SM-2I3ES GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-WFG8-0626-SM-3GILJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-TKQ2-1026-SM-33HB7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 Intestine TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Perturb_9023_KD_NR4A3_SRP324495 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -9.53553 POLR2A_HeLa-S3_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H2030 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.971507 Brain Lower Grade Glioma_LGG_TCGA-TM-A84Q-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MZ in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.68746 AMIGO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08253 C19orf47 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.3997 H3K4me3_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null negative regulation of metabolic process GO Biological Process Annotations 2015 1.0 null GTEX-RVPU-0011-R7A-SM-2XCAB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-U3ZN-2226-SM-3DB88 GTEx Tissue Sample Gene Expression Profiles 1.0 1.62476 GTEX-PW2O-1426-SM-48TCD GTEx Tissue Sample Gene Expression Profiles 1.0 0.90039 MEIS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.77985 Ppara JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.5624 GSE160373_1_v_7_pparg_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BICR 31 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.03138 H3ac_C2C12_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ZNF582 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.9966 ODF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.02435 superficial stratum of r7BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.00917 SPI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12206 H3K4me3_LNCaP clone FGC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null FOXP2 ENCODE Transcription Factor Targets 1.0 null TMEM54 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7054 Perturb_515_KO_IFI16_SRP281173 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 MEWO CCLE Cell Line Gene CNV Profiles -1.0 -2.671 TAF1_PFSK-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZBTB7A_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-TML8-1826-SM-32QOR GTEx Tissue Sample Gene Expression Profiles 1.0 1.83606 GTEX-XGQ4-2626-SM-4AT6B GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 Perturb_14179_KD_TP53_SRP200529 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.46851 layer 4 of ERCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07554 GTEX-OOBJ-2626-SM-2I3F6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 H3K9ac_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null FAM174C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.33282 GTEX-RVPU-2426-SM-2XCAR GTEx Tissue Sample Gene Expression Profiles 1.0 1.50303 GTEX-R45C-0008-SM-48FF2 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 H3K27ac_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null u937 HPA Cell Line Gene Expression Profiles 1.0 0.859389 SREBF1 JASPAR Predicted Transcription Factor Targets 1.0 null H3K79me2_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null E2F6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32315 TAF1_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null orbital frontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.85131 cerebellar cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.19596 SIN3A_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-P78B-1626-SM-2S1O1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.36964 HNF4G ENCODE Transcription Factor Targets 1.0 null phosphatase regulator activity GO Molecular Function Annotations 2015 1.0 null PMC8724844-bt-30-1-98-supple2.xlsx-GO_BP-TFAP4_TFAP4 Rummagene Transcription Factor Associations 2026 1.0 null IER3IP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.24723 GTEX-REY6-0726-SM-2TF4M GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 E2F1-18555785-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null CTCF_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_neural cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DAN-G Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.02765 doxorubicin_homo sapiens_gpl6947_gse25741 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null QGP1 CCLE Cell Line Gene Expression Profiles -1.0 -1.61367 H3K4me3_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Paraflocculus, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05 PMC9894241-pnas.2211429119.sd05.xlsx-G4_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST Rummagene Transcription Factor Associations 2026 1.0 null GTEX-OOBJ-1626-SM-2I3F7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.7593 GTEX-QDT8-0426-SM-32PKZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GSE205163,GSE205164_9_v_0_znf808_human RummaGEO Gene Perturbation Signatures -1.0 null MAFF_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ESRRB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.8453 GTEX-PLZ6-0008-SM-48TD5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 H3K4me3_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CEBPB_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_MCF-7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE223893_11_v_10_setd2_human RummaGEO Gene Perturbation Signatures -1.0 null IZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 3.34509 EM2 CCLE Cell Line Gene Expression Profiles 1.0 1.48685 POU2F2_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Sarcoma_SARC_TCGA-DX-A48K-01A-11R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-SUCS-1626-SM-32PLS GTEx Tissue Sample Gene Expression Profiles 1.0 1.5788 FOXC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9445 r7 part of parapyramidal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.00917 SAFB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.12149 UBTF_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null E2F6_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OB olfactory fiber layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08642 FEZF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 59.5547 posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.38072 OVISE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.03046 SNU601 CCLE Cell Line Gene Expression Profiles -1.0 -2.14855 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4843-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cortical amygdalar area, posterior part, lateral zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13331 CREB1_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null EP300_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-58-8392-01A-11R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Entorhinal area, medial part, dorsal zone, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11531 POLR2A_GM12892_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TTC642 DepMap CRISPR Gene Dependency 1.0 2.21665 posteroventral (inferior) parietal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.65491 SLC2A6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3858 HBA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54714 H3K27ac_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MZ in granular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.843555 BORCS6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49422 H3K4me1_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null USF1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QEL4-0626-SM-3GIJM GTEx Tissue Sample Gene Expression Profiles 1.0 1.17108 subthalamic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.18988 TERB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19408 GABPA_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_8942_KO_RB1_SRP220467 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 regulation of cellular metabolic process GO Biological Process Annotations 2015 1.0 null tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 superficial stratum of r2Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.54674 MAFK JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.2892 Primary somatosensory area, unassigned, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.5067 ZBTB33 ENCODE Transcription Factor Targets 1.0 null inferolateral temporal cortex (area TEv, area 20)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.17622 GTEX-XUZC-0626-SM-4BOPG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GSE147613_1_v_0_cisplatin_mouse RummaGEO Drug Perturbation Signatures 1.0 null YD15 CCLE Cell Line Gene CNV Profiles -1.0 -1.56771 CORL279 CCLE Cell Line Gene Expression Profiles -1.0 -1.8704 H3K4me3_HL-60_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-X8HC-0526-SM-4E3JA GTEx Tissue Sample Gene Expression Profiles 1.0 1.82771 HMGB4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80898 NIHOVCAR3 CCLE Cell Line Gene CNV Profiles 1.0 1.85728 GTEX-SN8G-0526-SM-32PLE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 Muscle-slow muscle cell Tabula Sapiens Gene-Cell Associations 1.0 6.18062 ZNF280C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16951 YH13 CCLE Cell Line Gene Expression Profiles -1.0 -1.73319 H3K4me3_GM12865_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-S4P3-0726-SM-4AD57 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-WHSB-0326-SM-3LK6K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 HOXD11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95467 BACH2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.3168 Lung squamous cell carcinoma_LUSC_TCGA-63-A5MY-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_GM12865_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null THP1 CCLE Cell Line Gene Expression Profiles 1.0 1.8496 Perturb_8955_Mut_RB1_SRP220467 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 RAD21 ENCODE Transcription Factor Targets 1.0 null H3K4me3_K562_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-RVPU-0011-R10A-SM-2XCAH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 INPP5E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06443 GTEX-X5EB-2426-SM-4E3HX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 PRELID1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.08686 SG in granular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.19784 ARMT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66715 Lung squamous cell carcinoma_LUSC_TCGA-56-7221-01A-11R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2897-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CLCC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17448 H3K4me3_HeLa-S3_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null ERF::HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.9094 PSS008 DepMap CRISPR Gene Dependency 1.0 2.75934 ZMIZ1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KCNS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91847 Supratrigeminal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01717 amygdaloid complex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.43619 H3K4me1_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-RNOR-2426-SM-48FDY GTEx Tissue Sample Gene Expression Profiles 1.0 0.958333 H3K4me2_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null A2058 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -3.62468 multiform (lateral) division of MD Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.18837 HCC2270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.35139 GABPA_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Retrosplenial area, dorsal part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34531 H3K4me1_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PMC9894241-pnas.2211429119.sd05.xlsx-G6_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST Rummagene Transcription Factor Associations 2026 1.0 null GTEX-QVJO-0126-SM-3GIK4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.74539 Posterolateral visual area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3616 MAX_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Visual areas Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.15229 GTEX-SN8G-0008-SM-4DM4X GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 H3K9ac_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MONOMAC6 CCLE Cell Line Gene Expression Profiles 1.0 2.31471 HCFC1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF558 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23438 MBD4_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XOTO-0006-SM-4B64T GTEx Tissue Sample Gene Expression Profiles 1.0 0.892539 KYSE-520 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20628 H3K4me1_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TAF1_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_7930_KD_ZCCHC8/ZFC3H1_SRP222099 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 12.855 ZKSCAN1 ENCODE Transcription Factor Targets 1.0 null MXI1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X88G-0326-SM-47JZ4 GTEx Tissue Sample Gene Expression Profiles 1.0 3.37994 GSE130715_1_v_0_budesonide_human RummaGEO Drug Perturbation Signatures 1.0 null RMI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41829 layer 4 of OCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39868 MXI1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ZNF485 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.86183 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LX-01A-11R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CYP2S1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15219 FOXA1_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-XG-A823-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ATF6B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.15416 MTFP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46966 GTEX-REY6-0326-SM-2TF5A GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 SNU216 DepMap CRISPR Gene Dependency 1.0 2.14822 TBK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13388 GTEX-SE5C-1326-SM-4BRUH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GSE165560_0_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null GSE131649_2_v_9_hemin_human RummaGEO Drug Perturbation Signatures 1.0 null GSE157777_1_v_3_foxa3_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_epithelial cell of proximal tubule_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null ATG14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98114 H3K27ac_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CBFB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01655 H3K4me3_WI38_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null TBL1XR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAF7_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NELFE ENCODE Transcription Factor Targets 1.0 null H3K4me3_cardiac mesoderm_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null VPS26B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88578 ZNF469 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9927 H3K4me3_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-Q2AG-0926-SM-48U1Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-X4LF-0426-SM-3NMB5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-U3ZG-0326-SM-47JXN GTEx Tissue Sample Gene Expression Profiles 1.0 1.26134 OCI-AML2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.19356 SK-MES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.31778 SNU869 CCLE Cell Line Gene CNV Profiles 1.0 1.96253 YY1_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NRF1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41P-01A-12R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inner CP in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.20981 RAB3A_Mutation - D77G point mutation_GDS2483_698_mouse_Hippocampus GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null muscular system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 G61 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.934554 H3K4me3_HEK293_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null SNU-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.55728 HOXD12::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.9329 JUND_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null KLE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.12939 hippocampus (hippocampal formation)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.33933 SNU1040 CCLE Cell Line Gene Expression Profiles 1.0 1.40907 IFT172 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.54113 r2 part of trigeminal sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06554 E2F6_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EZH2 ENCODE Transcription Factor Targets 1.0 null GSE149760_3_v_5_elof1_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-NL4W-0011-R10A-SM-2I3DY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 SEMA3F CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.75669 layer II of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.67478 POTEI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90059 orbital frontal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.12708 ATF2 ENCODE Transcription Factor Targets 1.0 null SNUC1 DepMap CRISPR Gene Dependency 1.0 3.04418 GSE168797_1_v_0_cannabidiol_human RummaGEO Drug Perturbation Signatures 1.0 null MJ DepMap CRISPR Gene Dependency 1.0 2.14927 TRAPPC13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45967 GTEX-X585-0008-SM-46MU4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 Perturb_15293_OE_Fos_SRP304877 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -11.8647 Skeletal Muscle Male Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.56376 H3K36me3_CH12.LX_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S7PM-0526-SM-3NM92 GTEx Tissue Sample Gene Expression Profiles 1.0 1.02298 POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_HL-60_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null SUZ12-20075857-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null MAP3K3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22324 GSE160373_6_v_4_pparg_mouse RummaGEO Gene Perturbation Signatures -1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YO-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hippocampus (hippocampal formation)_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.84638 H3K4me3_CH12.LX_mm9_5 ENCODE Histone Modification Site Profiles 1.0 null ZBTB20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88073 primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.01447 GRK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24073 H3K4me3_mononuclear cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-O5YW-1526-SM-3MJGL GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-XLM4-3126-SM-4AT6M GTEx Tissue Sample Gene Expression Profiles 1.0 0.947642 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LY-01A-31R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null WDR6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93115 posteroventral (inferior) parietal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.03442 IRF8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1051 SIN3A_PFSK-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-VUSG-1126-SM-4KKZQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 Entorhinal area, lateral part, layer 2b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.74565 H3K4me3_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null medial habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -3.21686 amygdaloid complex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.32033 PPP4R1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90622 ATF3_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S341-1826-SM-3K2AB GTEx Tissue Sample Gene Expression Profiles 1.0 1.22036 H3K27ac_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-UPK5-1826-SM-3GAEB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 SEC11C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15685 PNMA6F CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66796 GTEX-OXRO-1726-SM-3LK6C GTEx Tissue Sample Gene Expression Profiles 1.0 1.10576 POLR2AphosphoS5_PFSK-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null COMMD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52471 paracentral lobule, anterior part, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.85223 EP300_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CBX3_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 496100384_HIP_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.37996 SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null NUMBL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33373 TMEM216 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66677 SIN3A_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TEAD4_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U412-0226-SM-3NMC8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GSE164874_5_v_13_prednisolone_human RummaGEO Drug Perturbation Signatures 1.0 null DDX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52068 Skeletal Muscle Female Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.11671 GSE148200_0_v_2_gemcitabine_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-PWOO-1526-SM-48TCK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 smooth muscle HPA Tissue Protein Expression Profiles -1.0 -1.51613 Paragigantocellular reticular nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.47809 Anteromedial visual area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10418 GTEX-QVUS-0011-R3A-SM-3GAFD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 NSD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.65129 HL-60 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.58776 SIN3A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_13254_KD_Ncaph2_SRP073037 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.15275 Agranular insular area, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42236 NPLOC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3894 GTEX-S4P3-1626-SM-3K2AZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.0543 GTEX-WOFM-0726-SM-3MJF8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-TMMY-0426-SM-33HBB GTEx Tissue Sample Gene Expression Profiles 1.0 1.03991 NFE2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null amygdaloid complex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.835598 TTC709 DepMap CRISPR Gene Dependency 1.0 4.57928 CAL-12T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.872123 GTEX-X638-0326-SM-47JY1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.97511 JUN_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null COX11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29694 GTEX-NFK9-0626-SM-2HMIV GTEx Tissue Sample Gene Expression Profiles 1.0 1.08092 GTEX-PWCY-0426-SM-48TCW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 H3ac_myocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Entorhinal area, medial part, dorsal zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.21179 RNF126 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.11025 VIIIA, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.8109 GTEX-NL3H-0011-R3a-SM-2I3GL GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-RU72-0011-R5A-SM-2TF6U GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 Infralimbic area, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15421 mRNA_POU5F1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null GTEX-WL46-2926-SM-3LK82 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 H3K4me3_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null SIX5_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NR2F2_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SOX10 MotifMap Predicted Transcription Factor Targets 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4988-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-RVPV-1226-SM-2TF73 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 H3K4me3_BJ_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-T5JW-1826-SM-3GAE1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.56848 H3K4me3_cardiac muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null METRN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8713 MAX_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1693 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.84374 ZNF722 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.77897 GTEX-T8EM-1226-SM-4DM5J GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 H3K4me3_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_keratinocyte_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GSE112202_5_v_2_digoxin_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-XLM4-0011-R9A-SM-4AT45 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 SKM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.2694 H3K4me3_cardiac fibroblast_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null USF1_A549_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null Muscle-fast muscle cell Tabula Sapiens Gene-Cell Associations 1.0 7.50194 H2AFZ ENCODE Transcription Factor Targets 1.0 null lateral intermediate part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.97274 TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null GTEX-TKQ1-1426-SM-4GICK GTEx Tissue Sample Gene Expression Profiles 1.0 1.45678 FADU CCLE Cell Line Gene CNV Profiles 1.0 2.22371 inner SZ in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.69285 eGFP-HDAC8_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null USF2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null G84 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.859165 Acute Myeloid Leukemia_LAML_TCGA-AB-3005-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PBX3_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A4XJ-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TBX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.8733 H3K4me3_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.68047 HOXB6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94591 USF2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XAJ8-1026-SM-47JY9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.09065 H3K79me2_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null OVISE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.5665 HBA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60802 GTEX-N7MT-0126-SM-2D7VT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 Perturb_7879_KD_EXOSC3_SRP266190 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 8.8868 Retrosplenial area, dorsal part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20057 GTEX-XQ8I-2326-SM-4BOQC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 head TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null H3K4me3_brain microvascular endothelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-44-8119-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null USF1_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TM2D2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5064 Lung squamous cell carcinoma_LUSC_TCGA-85-8354-01A-31R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DHRS7B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24291 H3K9ac_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CLPTM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39108 MYOD1_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null FRMD8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37724 Entorhinal area, lateral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.74565 GTEX-RU72-1326-SM-2TF6T GTEx Tissue Sample Gene Expression Profiles 1.0 1.71874 GSE136627_7_v_1_hdac4_mouse RummaGEO Gene Perturbation Signatures -1.0 null LMTK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.55859 lateral subdivision of BNST Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.75855 GSE160373_6_v_3_pparg_mouse RummaGEO Gene Perturbation Signatures -1.0 null CAKI1 CCLE Cell Line Gene CNV Profiles 1.0 1.36494 GTEX-QVJO-0011-R8A-SM-447C7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 ZNF664 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47219 COV504 CCLE Cell Line Gene CNV Profiles 1.0 2.58828 GTEX-XBED-2626-SM-4E3J5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.94389 GTF2E2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58853 GTEX-RTLS-2626-SM-46MUJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 intermediate stratum of r7BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3491 H3K4me3_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null VZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.15524 GTEX-XLM4-1026-SM-4AT51 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 TEF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.70206 MVK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62731 KMS-27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.958536 PANC 05.04 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.65147 MDAMB436 CCLE Cell Line Gene CNV Profiles -1.0 -1.38873 H3K4me3_MEL cell line_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5010-01A-02R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-WQ-A9G7-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-7292-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PAX5_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_fibroblast of mammary gland_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-U8T8-2226-SM-3DB95 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 ZBTB44 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83191 AGFG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5213 outer CP in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.22735 EP300_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SMC3 ENCODE Transcription Factor Targets 1.0 null CCZ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74446 GTEX-XBEC-0008-SM-4AT3X GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-X4XY-0626-SM-4E3IN GTEx Tissue Sample Gene Expression Profiles 1.0 2.84592 H3K4me1_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null OCI-AML5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.83297 MT-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.02987 ZNF85 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.2072 H3K4me1_CD34 Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null negative regulation of phosphatase activity GO Biological Process Annotations 2015 1.0 null ARFGAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9055 PXN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9349 GATA3_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null facial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.862191 H3K4me3_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Paragigantocellular reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37437 UBE2Z CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8093 S117 DepMap CRISPR Gene Dependency 1.0 2.61967 BHLHE40_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Jurkat_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE103068_5_v_3_volasertib_human RummaGEO Drug Perturbation Signatures -1.0 null MBD3L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.80658 MKN-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.75265 GTEX-XBEC-0126-SM-4GIDT GTEx Tissue Sample Gene Expression Profiles 1.0 0.830874 r7 part of the basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55481 VZ in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.14916 Entorhinal area, medial part, dorsal zone, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.76446 Piriform-amygdalar area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.52685 H3K4me3_GM12878_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null 496100277_FWM_no dementia_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.50409 H3K4me1_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NFIC ENCODE Transcription Factor Targets 1.0 null GTEX-X5EB-0008-SM-46MU3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GSE127790_13_v_3_zcchc8_mouse RummaGEO Gene Perturbation Signatures 1.0 null ELK4_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC4521181-oncsis201520x8.pdf-141-ZGPAT_ZGPAT Rummagene Transcription Factor Associations 2026 1.0 null HN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.31738 LACC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78201 NODAL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.71059 Primary visual area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.78991 GTEX-REY6-0826-SM-2TF4S GTEx Tissue Sample Gene Expression Profiles 1.0 1.06484 GTEX-O5YT-0226-SM-32PK5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GSE239541_8_v_4_bmal1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A8NY-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null striatum_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.19526 POLR2AphosphoS5_U-87 MG_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JHOS4 CCLE Cell Line Gene CNV Profiles 1.0 2.77722 GTEX-X5EB-0726-SM-46MVR GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 ZNF35 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.95296 GTEX-WHSE-0006-SM-3NMBW GTEx Tissue Sample Gene Expression Profiles 1.0 1.01248 YY1_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZSCAN31 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.3357 TCF3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ENSG00000170846 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.69918 GTEX-PW2O-1226-SM-48TCH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 POLR2A_GM18505_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WWYW-0526-SM-3NB2W GTEx Tissue Sample Gene Expression Profiles 1.0 1.91419 regulation of phosphorus metabolic process GO Biological Process Annotations 2015 1.0 null superficial stratum of ERCx (cortical plate/marginal zone) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44614 PMC11067031-pnas.2317690121.sd06.xlsx-gene_list_14_txt-Differentially_expressed_genes_between_PML_RARA_GFP_vs_C88A_PML_RARA_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA Rummagene Transcription Factor Associations 2026 1.0 null GDE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.78109 H3K4me1_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-PVOW-1026-SM-2XCF9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 DNAJC9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.25803 SCC4 CCLE Cell Line Gene CNV Profiles -1.0 -1.60343 MYOD1 ENCODE Transcription Factor Targets 1.0 null biological_process GO Biological Process Annotations 2015 1.0 null Periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08647 intercalated nucleus of medulla Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.923456 GRK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58553 UCP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10632 REST_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null SP in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.44295 NPR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.29703 intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null ADRA2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07334 cuneate nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.867419 GSE210662_2_v_1_znf165_human RummaGEO Gene Perturbation Signatures 1.0 null ZNF208 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.6389 GTEX-OIZI-0226-SM-2XCEE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 ZNF331 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86301 regulation of phosphatase activity GO Biological Process Annotations 2015 1.0 null H3K4me3_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PL-21 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.981575 LDB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52993 GTEX-POMQ-0426-SM-3P61G GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 TBP ENCODE Transcription Factor Targets 1.0 null PTPN13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98953 H3K4me3_C2C12_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ventrolateral preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28463 HOP-92 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.37323 Entorhinal area, medial part, dorsal zone, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.09713 H3K4me3_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null H2AFZ_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_CH12.LX_mm9_4 ENCODE Histone Modification Site Profiles 1.0 null PMC10528072-NIHMS1928302-supplement-5.xlsx-NEUROD1-target_genes-AANAT_NEUROD1 Rummagene Transcription Factor Associations 2026 1.0 null TAF1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNRNP25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33348 RNF8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7738 hsa-miR-548i TargetScan Predicted Conserved microRNA Targets 1.0 0.436802 ATF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00725 GTEX-QV31-0326-SM-447BM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 RAMP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.21296 precuneus, right, superior lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.46043 SKNO1 DepMap CRISPR Gene Dependency 1.0 3.26199 Cri-Du-Chat syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.203 TCF12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0656 SMC3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE133516_0_v_2_kat7_human RummaGEO Gene Perturbation Signatures 1.0 null HCC38 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.88757 496100492_TCx_probable Alzheimer's disease_no TBI_89_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.51936 GTEX-T6MO-1526-SM-4DM57 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 occipital neocortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.0789 animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null ELF1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SG in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.72373 JUND_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RN64-0326-SM-2TC5J GTEx Tissue Sample Gene Expression Profiles 1.0 1.4753 reticulotegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.956968 KHM-1B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.26656 CBX3 ENCODE Transcription Factor Targets 1.0 null KIAA1586 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73405 motor nucleus of trigeminal nerve, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.24079 H3K27ac_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Primary visual area, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.89078 KP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.15336 inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.56725 GTEX-RNOR-0526-SM-2TF4O GTEx Tissue Sample Gene Expression Profiles 1.0 1.183 H3K4me1_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null primary motor cortex (area M1, area 4)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.43547 GTEX-P4QS-0726-SM-3NMCZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-O5YV-0226-SM-48TBY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 SCD_KO_GSE24243_46_mouse_Skin (8-9 wk) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GTEX-SIU8-0526-SM-2XCDP GTEx Tissue Sample Gene Expression Profiles 1.0 1.42218 MYC_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNAI2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.2659 NSUN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60705 tissues, cell types and enzyme sources TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 SW 837 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.05743 H3K4me3_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PRMT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98647 GTEX-TMMY-0005-SM-33HBN GTEx Tissue Sample Gene Expression Profiles 1.0 0.960323 GTEX-U8T8-0008-SM-4DXSP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTF2F2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44551 UBTF_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZBTB7A_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Central nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Perturb_12949_KD_HOXBLINC_SRP149346 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.84956 LITAF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78608 APBB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98765 H3K4me3_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HABP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.44053 ATF3_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XAJ8-1326-SM-47JYT GTEx Tissue Sample Gene Expression Profiles 1.0 0.852384 SSBP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88456 H3K4me3_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-P4PQ-2626-SM-33HC9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 HESX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3511 KELLY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.50323 Medial geniculate complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.88815 PACSIN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76624 GTEX-QEL4-0726-SM-3GIJ5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-QXCU-0926-SM-48FEP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 TMEM181 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03732 GCM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62131 POLR2AphosphoS5_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-POYW-0008-SM-48TE4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 TCF12_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EGR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NFIC_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null USF2_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SRC_activemutant_51_GSE15815 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.36051 TOMM70 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46643 GSE201309_5_v_0_matrine_human RummaGEO Drug Perturbation Signatures 1.0 null inner SZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.79995 Pancreatic adenocarcinoma_PAAD_TCGA-YH-A8SY-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-R55D-1826-SM-48FEF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 TEAD4_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null KDM4A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TCF7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19773 TARBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.77044 H3K27ac_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MYC_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null IMR32 DepMap CRISPR Gene Dependency 1.0 5.64054 GTEX-QV44-2026-SM-2S1RD GTEx Tissue Sample Gene Expression Profiles 1.0 1.55207 hippocampus (hippocampal formation)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.40852 MV411 CCLE Cell Line Gene Expression Profiles 1.0 2.13763 GTEX-NL3H-0011-R4a-SM-2I3GK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-XV7Q-2926-SM-4BRUL GTEx Tissue Sample Gene Expression Profiles 1.0 1.19625 GTEX-VUSG-1226-SM-4KKZF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 GTEX-WFON-1426-SM-4LVMT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08825 MONOMAC1 CCLE Cell Line Gene Expression Profiles 1.0 1.99119 H3K79me2_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2AphosphoS5_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null FAM83G CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.12199 H3K4me3_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null ML-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.44249 E2F6 ENCODE Transcription Factor Targets 1.0 null SCC-9 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.928472 Accessory olfactory bulb, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11306 ENTPD6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.08156 EP300_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mediodorsal nucleus of thalamus_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.959678 H3K4me3_kidney epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-R55E-2726-SM-48FCX GTEx Tissue Sample Gene Expression Profiles 1.0 0.955684 H3K4me2_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of pedal digit skin_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BFTC-905 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_mammary epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Duodenum Mucosa Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 1.13617