association	dataset	threshold value	standardized value
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14109
HSC-39	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.68175
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RNOR-0526-SM-2TF4O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.3489
LC1SQSF	CCLE Cell Line Gene CNV Profiles	-1.0	-2.00401
lingual gyrus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02459
CRCGN012_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.72195
BRD-K67868012_PI-103_A549_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-S4Z8-0526-SM-4AD4T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.869464
BRD-K79020643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.31608
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09115
BRD-A39646320_H7270_PHH_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K23366960	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79528
AD-20-AA40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.259542
neuroblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.06018
GTEX-XUW1-0226-SM-4BOOS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2799
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3C3-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
coated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.098991
KLF4-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE189683_1_v_2_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MM1-R cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.766
GTEX-R53T-0008-SM-48FEW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65831
TBX2-33478486-IMR90-HUMAN-LUNG	ChEA Transcription Factor Targets 2022	1.0	null
K562	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.05692
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
BRD-K00765599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29469
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-U64521890_XMD16-144_MCF7_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HC-18-NB46_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.312358
DA-15-PU65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.209579
tumors	GeneRIF Biological Term Annotations	1.0	null
CTCF_medulloblastoma_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE174701_4_v_3_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
BCL3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BA-59-EN38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.229108
BRD-K56751279_Y-39983_HEPG2_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K44204252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67532
BRD-K63663384	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06732
CRCGN015_MCF10A.TP53.M_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.13925
SGK3	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WFG8-2226-SM-3GIL9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.38518
BRD-K79239947_PF 573228_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K02130563_S1030_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN017_MCF10A.TP53.M_24H:D22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7108
Flavopiridol	DeepCoverMOA Drug Mechanisms of Action	1.0	0.69
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
BRD-U60236422_WH-4-025_HT29_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K49328571_dasatinib_A375_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
USF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K17743125_belinostat_HCC515_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PDCD4	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K08109215_I-BET_HCC515_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5100-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NPJ8-0011-R1a-SM-33HCB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05909
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040532
hsa-miR-4260	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
AA-87-EI21_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.288094
DF-00-BX35_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.428496
p1 part of parabrachial pigmented nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07648
ketoprofen-3729	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4923-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K18163752_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TAPBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2664
BRD-K99982687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29648
Entorhinal area, medial part, ventral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76545
GSE193258,GSE193259_9_v_13_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE216274,GSE216292_4_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
intermediate stratum of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43214
AA-62-HP31_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.695506
hippocampus (hippocampal formation)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.889626
HCC4006	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.870758
Carcinogenesis	DisGeNET Gene-Phenotype Associations	1.0	null
PMC4909989-ncomms11840-s2.xlsx-up-regulate-The_YAP_TEAD4-FL_YAP_TEAD4-S_and_YAP_RBM4_regulated_genes_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.11896
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.40186
EB-90-BR21_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.229249
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.89687
AF-30-GH67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.295822
Ebf4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.6635
MDAMB361	CCLE Cell Line Gene CNV Profiles	1.0	2.36402
BRD-K12867552_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A_CA_04_2009_4dayMOI-10^3_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.58111
PLA2G4B	Pathway Commons Protein-Protein Interactions	1.0	null
Posterolateral visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0885
DCTN2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K00317371_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE189683_3_v_2_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ATP6V1A	Pathway Commons Protein-Protein Interactions	1.0	null
TD-69-UA90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.211111
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.42535
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.74223
BRD-K12502280_TG-101348_SKBR3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE193258,GSE193259_9_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNU308	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47156
BRD-K54233340_Dorsomorphin dihydrochloride_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
AE-56-SL06_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.273261
BRD-K86797399_pracinostat_HCC515_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE226091,GSE226092_3_v_2_sall1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12801
POLR2A_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN013_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.24473
BRD-K23984367_S1040_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K18ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_11549_KD_hNRNPK_SRP362515	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-NFK9-1626-SM-3LK5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35484
BRD-K86102179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01197
GTEX-S4UY-1226-SM-4AD51	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05925
DYNC1LI2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE215155_0_v_1_golph3_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K11003742	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60265
GTEX-Q2AG-0011-R2A-SM-2HMIT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07039
cerebellar cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.41532
C170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.970537
lymphoid tissue	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TRIM28	ENCODE Transcription Factor Targets	1.0	null
medial parabrachial nucleus,right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.32193
BRD-K72866723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13145
PMC11309649-medi-103-e37185-s002.xlsx-Sheet1-FOS_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
GSE182181_1_v_0_ricolinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE173997_1_v_0_clic4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K51398207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41777
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
AP1M2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K00337317_NU-7441_A549_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K22503835_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K53903639_480743.cdx_AGS_6.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6407-02B-11R-A36H-07,TCGA-DU-6407-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
including	GeneRIF Biological Term Annotations	1.0	null
ZD-74-FC07_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.221415
CHD4	Pathway Commons Protein-Protein Interactions	1.0	null
DYNC1I2	Pathway Commons Protein-Protein Interactions	1.0	null
anteroventral periventricular preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.90863
posteroventral (inferior) parietal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.40869
GTEX-TML8-1926-SM-32QOS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860866
BRD-K01436366_XMD-1150_LNCAP_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
WD-26-EB85_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.257835
GTEX-OHPL-2026-SM-3TW8R	GTEx Tissue Sample Gene Expression Profiles	1.0	2.63975
layer 3 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67263
GSE193258,GSE193259_2_v_12_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.060978
BRD-U64521890_XMD16-144_A549_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ethotoin-3809	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-let-7b-5p	MiRTarBase microRNA Targets	1.0	null
GSE142210_3_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.72627
r5 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1906
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K02607075_-666_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K08659289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.12901
GE-29-ZM45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.324219
MTOR_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
BRD-K23165181_NCGC00241357-01_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN015_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.32224
GTEX-REY6-0826-SM-2TF4S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33391
GTEX-WZTO-0011-R10B-SM-4E3KB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09338
GTEX-OOBK-1026-SM-48TC2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02026
chlorcyclizine-3810	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE216540_1_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
establishment of protein localization	GO Biological Process Annotations 2015	1.0	null
BRD-K64890080_BI-2536_BT20_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
brain_3b	HPA Tissue Sample Gene Expression Profiles	1.0	1.43497
TAF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08334
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.25207
cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041944
superficial stratum of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74081
Postsynaptic Golgi apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.024
DA-40-HO94_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.435447
Main olfactory bulb, inner plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06035
COPI-coated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.078
b19	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.572
MAPK3	Pathway Commons Protein-Protein Interactions	1.0	null
periventricular stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1896
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SPCS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08606
GSE168697_0_v_1_wdr6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HS 255.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.63854
N-acetyl-L-leucine-3085	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-RUSQ-0326-SM-47JWS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17153
BRD-K38791044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10808
BRD-K04269696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64769
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.78695
GSE144484_0_v_3_mllt6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47497
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.31172
BRD-A39996500_radicicol_MCF10A_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CA-96-UO48_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.445729
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JC-63-BE61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.305299
PA-75-VL17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.628962
imatinib_homo sapiens_gpl96_gds3048	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SLC39A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0037
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.78796
BRD-K59962020_2858522_HT29_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AA-62-HP31_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.206254
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM5A-27292631-CHIP-SEQ-BREAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ATG5	Pathway Commons Protein-Protein Interactions	1.0	null
Neuroblastoma	DisGeNET Gene-Disease Associations	1.0	null
ovary	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.305722
H3K36me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-QH-A6CU-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TF-23-DD23_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.362989
MTA3	ENCODE Transcription Factor Targets	1.0	null
u87	HPA Cell Line Gene Expression Profiles	1.0	0.896697
BRD-K88613983	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01244
BRD-K76674262_-666_SKB_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BLOC1S6	Pathway Commons Protein-Protein Interactions	1.0	null
GSE124304_1_v_0_abl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4944136-srep28995-s2.xls-DPRX-gene_DPRX	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K43435656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44372
hsa-miR-3176	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE100316_3_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ERLIN2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K81418486_vorinostat_PL21_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.8567
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nitrogen compound transport	GO Biological Process Annotations 2015	1.0	null
GSE179880_7_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAFK_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K26767874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46707
Prostate adenocarcinoma_PRAD_TCGA-HC-7747-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KE-73-XV62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.86961
SA-31-VB03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.7587
CRCGN017_MCF10A.WT.HP_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.8958
Secondary motor area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53468
BRD-K33805195	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02368
EF-85-DA07_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.313498
LOU-NH91	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15291
brain	HPA Tissue Gene Expression Profiles	1.0	1.44383
GSE77108_4_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RB-22-TT44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.309957
FOSL2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.27625
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3TU-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7PW-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A50737080_CGK-733_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A02481876_Importazole_LOVO_6.0_h_60.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
exocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.31681
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64068
IE-80-DC24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.694115
BRD-K80336250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34051
GSE239844_1_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.63535
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22588
amygdala	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K89806367	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55163
FD-86-NE74_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.201585
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_GSC-Unnamed_2_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A7VF-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paclitaxel-5320	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
phenformin-2312	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:C02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0588
KLF17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	83.6886
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1242
GTEX-X4EO-0526-SM-3P5Z3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.98401
facial motor nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21712
GSE189789_0_v_1_oridonin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K25718630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35353
JD-44-KF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.49561
DC-08-CM08_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.25705
hsa-miR-520e	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
XE-29-LT20_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.294551
meclocycline-3277	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cerebellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.099082
superficial stratum of r3Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31417
BRD-K09951645_dabrafenib_A375_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K53903639_480743.cdx_HT29_24.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KIF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78892
BRD-K87447060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.17649
BB-44-SX65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.221961
posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00107
HNF4A	Pathway Commons Protein-Protein Interactions	1.0	null
ID-00-IC14_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.288055
NC-35-BF58_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.224091
liver_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.92864
Brain - Nucleus accumbens (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.1891
SW1783	GDSC Cell Line Gene Expression Profiles	1.0	1.44191
BRD-K41829399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17231
CRCGN016_MCF10A.TP53.M_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.12314
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.94582
BRD-K75041300	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09721
GTEX-OHPN-0011-R5A-SM-2I5FF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12631
GTEX-TKQ2-1726-SM-4DXUP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01498
CRCGN009_HEPG2_24H:K16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2268
BRD-A19037878_trichostatin A_PL21_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
wortmannin-4467	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053101
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDIPT	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K02708799_GSK-1059615_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K29415052_NVP-BGT226_A375_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-RM2N-1626-SM-2TF5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22887
GSE97352_1_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN012_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25216
GSE139239_3_v_5_ddr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-6682-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RL7	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.2142
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052526
BRD-K31992830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68229
GSE169205_0_v_5_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
AE-18-ZM98_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.245844
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27192
H4K8ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
MT-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03455
ELF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RHOT1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A52377240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54091
UD-85-WR81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.224322
BRD-K33897007	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00222
trochlear nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.81939
pre-B-lymphocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.662
BRD-K61134709	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10281
PRKAR2A	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K44760023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16051
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15243
BRD-K17743125_belinostat_MCF7_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K41895714_AS-605240_A375_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FD-74-LD52_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.367393
BRD-K86761848_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WK11-2526-SM-3NM9Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934068
GSE199606_2_v_7_csf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
heptaminol-1866	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K05804044_AZ-628_A375_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K47326075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72049
FA-03-CZ62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.257309
LA-42-ER00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.453813
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PBX3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K02624724	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03416
CRCGN017_MCF10A.TP53.M_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01762
Acute Myeloid Leukemia_LAML_TCGA-AB-2832-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AB-33-EM56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.396993
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IC-76-JU42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.10442
GD-07-HO70_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.374491
LETM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03235
GSE216274,GSE216292_4_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE167474_1_v_3_naa40_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
furaltadone-4313	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE140074_1_v_0_kif20a_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K73528610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10958
CRCGN014_HEPG2_24H:F08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.66383
YKG-1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.58106
NAT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24294
CRCGN017_MCF10A.TP53.M_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.66601
BA-19-VU85_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.318553
GSE239688_2_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ND-15-RC31_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.246831
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42539
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-R55E-2726-SM-48FCX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15514
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE179880_10_v_6_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Presubiculum, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38847
smoothmuscle_8c	HPA Tissue Sample Gene Expression Profiles	1.0	1.05401
CDC5L	Pathway Commons Protein-Protein Interactions	1.0	null
GSE160817_2_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211983_1_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
WD-65-PA90_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.299391
USF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FA-80-DR66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.0223
CRCGN014_HEPG2_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.94058
CE-18-AP15_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.23664
BRD-K60866521_idelalisib_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K38131403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94769
AC-74-ZA35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.56577
ventrolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.42044
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
MAX_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EXOC7	Pathway Commons Protein-Protein Interactions	1.0	null
AB-84-PK04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.567404
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JA-26-YQ32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.306063
CRCGN017_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.46703
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.344517
BRD-K06537903	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11422
GSE146982_7_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QV31-0226-SM-447BO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34776
BRD-K17743125_belinostat_HCC515_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE205163,GSE205164_3_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23717
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE130383_2_v_0_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
shsy5y	HPA Cell Line Gene Expression Profiles	1.0	0.959356
DD-75-HY40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.70669
VI, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.41022
GTEX-QMRM-0008-SM-447B1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26165
Lung squamous cell carcinoma_LUSC_TCGA-33-6738-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.903584
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
YY1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE185519_4_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-3184	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K97748753	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.18664
BRD-K43375231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.33362
PMC7300082-41598_2020_66556_MOESM11_ESM.xlsx-Supplementary_Table_10-CEBPD_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
PIN1	Pathway Commons Protein-Protein Interactions	1.0	null
FA-47-IB34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.326749
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.6838
BRD-K94518115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62378
GTEX-TMZS-0326-SM-3DB9P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29941
BRD-K86797399_pracinostat_MCF7_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K51556300_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Creb5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.9989
FA-92-JL46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.333995
PMC11950762-BLOODA_ADV-2024-014354-mmc2.pdf-22-ETV4_ETV4	Rummagene Transcription Factor Associations 2026	1.0	null
496100523_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09693
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.996711
AB-33-EM56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.404992
GSE185635_0_v_1_ncor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SCFD1	Pathway Commons Protein-Protein Interactions	1.0	null
VPS33A	Pathway Commons Protein-Protein Interactions	1.0	null
vitamin c_homo sapiens_gpl570_gds3635	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K37336973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78493
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K94325918_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SNU-719	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.45039
GSE130217_5_v_3_sesn2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
c8166	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.213
S0-EE-WJKI_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.543357
BRD-K04887706_AKT-inhibitor-1-2_PC3_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.2927
AA-33-DN24_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.2198
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12801
SEPT2	Pathway Commons Protein-Protein Interactions	1.0	null
brain_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.43795
CRCGN008_HEPG2_24H:O13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.2164
EGFR_drugactivation_20_GDS2146	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.88278
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A553-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XV7Q-1526-SM-4BRWB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14589
RB-34-TO07_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.231224
GSE233647_4_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4420-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063352
CRCGN015_MCF10A.TP53.M_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.34145
GSE151782_2_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A82F-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN013_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.51753
BRD-K20526256_HG-14-10-04_A375_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC12749419-41598_2025_28826_MOESM3_ESM.xlsx-RFT_iBody3_triplicate-Genes_MBD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE217541,GSE217543_0_v_1_tet1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PLIN3	Pathway Commons Protein-Protein Interactions	1.0	null
BE-79-QU25_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.261049
BRD-K21680192_mitoxantrone_PC3_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN017_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.69555
Ventral posterolateral nucleus of the thalamus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04954
GSE185519_4_v_7_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CDC42BPB	Pathway Commons Protein-Protein Interactions	1.0	null
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K48488978_YM-201636_MCF10A_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.968615
thiethylperazine-5756	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DIDO1	Pathway Commons Protein-Protein Interactions	1.0	null
AE-39-DG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.50435
CRCGN017_MCF10A.TP53.M_24H:P21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.10001
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4813-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.78655
SREBF2	JASPAR Predicted Transcription Factor Targets	1.0	null
JD-58-MV19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.240965
IGR1	CCLE Cell Line Gene CNV Profiles	1.0	1.73429
GTEX-T5JC-2426-SM-3NMDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23093
STX12	Pathway Commons Protein-Protein Interactions	1.0	null
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K79965790	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46028
CRCGN010_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.15415
GSE125014_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K54606188_(+)-JQ1_HA1E_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K30661365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91526
monastrol-681	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.59585
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	1.0	1.35121
BRD-K96209756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04247
GTEX-XYKS-0426-SM-4BRW4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7894
BRD-K21025364_NVP-TAE226_MCF7_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JA-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH3255	CCLE Cell Line Gene CNV Profiles	1.0	1.97965
Amygdala	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.031
GSE147876,GSE147877_4_v_6_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SMC4	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RNOR-0008-SM-48FEY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931536
GSE113734_1_v_0_qprt_human	RummaGEO Gene Perturbation Signatures	1.0	null
VPS4A	Pathway Commons Protein-Protein Interactions	1.0	null
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057353
GSE144500_8_v_2_ventx_human	RummaGEO Gene Perturbation Signatures	1.0	null
WA-62-RP29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.265196
IPCEF1	Pathway Commons Protein-Protein Interactions	1.0	null
Paragigantocellular reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58825
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A182-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YA-78-MS95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.25728
GSE173997_3_v_0_clic4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AC-36-TL21_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.268544
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A47O-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRCA1	ENCODE Transcription Factor Targets	1.0	null
GTEX-POMQ-0426-SM-3P61G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04491
Genistein	CTD Gene-Chemical Interactions	1.0	null
PPP1R7	Pathway Commons Protein-Protein Interactions	1.0	null
STX16	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QMR6-0008-SM-447AV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06912
GSE240386,GSE242143_8_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
participating	GeneRIF Biological Term Annotations	1.0	null
Zeta DNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.049
CRCGN015_MCF10A_48H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9789
MHHNB11	CCLE Cell Line Gene Expression Profiles	1.0	1.69159
mediodorsal nucleus of thalamus_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05334
hsa-miR-323b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Prostate adenocarcinoma_PRAD_TCGA-G9-6496-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T5JC-0011-R10A-SM-32PM2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38686
BRD-K34425773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16443
Uterine Carcinosarcoma_UCS_TCGA-N9-A4PZ-01A-22R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.98015
VMRCLCP	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48701
BRD-K67578145_GDC-0879_A375_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE201668_0_v_1_ncor2_human	RummaGEO Gene Perturbation Signatures	1.0	null
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-QV44-2026-SM-2S1RD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01392
GSE211177,GSE211178_0_v_1_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GA-28-SS67_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.756726
VZ in subgenual cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13078
BRD-K21680192_mitoxantrone_MCF10A_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN017_MCF10A.TP53.M_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.74447
PLXNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39317
BRD-K33863933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24045
FF-28-ES17_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.568
RAD21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00142
SNUC5	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58928
EP300_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042893
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06207
BRD-K05804044_AZ-628_A375_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5953
Uterine Carcinosarcoma_UCS_TCGA-N7-A4Y8-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K94012289_OSI-027_SKBR3_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DE-98-FC24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.251618
T47D	CCLE Cell Line Gene CNV Profiles	1.0	1.60342
hsa-miR-302b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
AB-64-ZX70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.17251
12,13-EODE-1108	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-SJXC-0126-SM-2XCFF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74043
EA-93-KT88_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.330668
MVP	Pathway Commons Protein-Protein Interactions	1.0	null
Accessory olfactory bulb, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18857
17009876-tableS1b	GeneSigDB Published Gene Signatures	1.0	null
EIF2B4	Pathway Commons Protein-Protein Interactions	1.0	null
anterior amygdaloid area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.913422
GTEX-T5JW-0326-SM-4DM6J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00027
cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K56196992_-666_NEU_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CP-690334-01-3826	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GABPA_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K50604515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9378
Cervix - Ectocervix	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.962013
ELK1	ENCODE Transcription Factor Targets	1.0	null
PLEKHA2	Pathway Commons Protein-Protein Interactions	1.0	null
TE-5	GDSC Cell Line Gene Expression Profiles	-1.0	-1.78479
GSE125014_1_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K93747373_HG-5-113-01_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EPHA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17454
r3 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07951
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.56523
CB-36-QH71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.336899
NFATC1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K81651477_Parthenolide_MCF7_24.0_h_20.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MDAMB134VI	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.11912
PMC10625120-ADVS-10-2304638-s002.xlsx-Table_S6-Table_S5_The_RNA-seq_of_KLF5_in_OVCA420_cells_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
ESO26	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.78132
TF-77-DW08_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.594774
phenelzine-3802	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN014_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	10.0
GSE148252_1_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mantle zone of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33348
BRD-K68336408_Tyrphostin AG 1478_AGS_6.0_h_56.78_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-PWCY-0726-SM-48TCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1518
GTEX-WL46-0626-SM-3LK7R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26215
BRD-K18737347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58938
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.899753
BCAP29	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-R55D-0008-SM-48FEV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87866
BRD-K83475223	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15664
cc81	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.983
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.0608
TRRAP	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VW-A8FI-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.08264
bone cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.082069
CRCGN015_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.3318
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
HEPG2	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.09026
caudal (posterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.869916
CRCGN016_MCF10A.TP53.M_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.9341
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.59701
TFDP1_02_71	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59699
Radicicol	DeepCoverMOA Drug Mechanisms of Action	1.0	1.18
RHOB	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-T8EM-0526-SM-4DM64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898509
DU145	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.68731
RAB33B	Pathway Commons Protein-Protein Interactions	1.0	null
RHOT2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02567
BRD-K88429204_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K02624294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78322
EC-82-LV30_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.27956
Accessory olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22212
GTEX-RWS6-0426-SM-47JXH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842397
RMND1	Pathway Commons Protein-Protein Interactions	1.0	null
MRPS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05162
CRCGN013_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.72935
SMYD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61167
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.67804
USP8	Pathway Commons Protein-Protein Interactions	1.0	null
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59983
CRCGN010_HEPG2_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.57657
GTEX-UJHI-0008-SM-4IHL1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8567
CREB1	JASPAR Predicted Transcription Factor Targets	1.0	null
chlorprothixene-5291	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
JA-32-HE94_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.248914
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0786
Esophagus - Mucosa	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.827095
CA-56-GE89_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.396536
BRD-A71459254_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCIH2170_LUNG	CCLE Cell Line Proteomics	1.0	10.4541
H3K4me1_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN008_HEPG2_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4048
temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K42728290_NVP-BGJ398_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K86838462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28151
GSE128730_3_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FAM129B	Pathway Commons Protein-Protein Interactions	1.0	null
SPTAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21838
POU5F1-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE239688_2_v_3_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10592471-NIHMS1912771-supplement-2.xlsx-NR2F1-Ind-Upregulated_NR2F1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K04887706_AKT-inhibitor-1-2_PC3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MU-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P44H-0726-SM-48TBT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78788
CRCGN012_HEPG2_24H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.49411
GSE112860_5_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11746
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157F_vs_MSX1-Gene_name_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K36382446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37907
GTEX-PLZ5-0426-SM-3P612	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32994
TAP1	Pathway Commons Protein-Protein Interactions	1.0	null
laterodorsal tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05253
CASK	Pathway Commons Protein-Protein Interactions	1.0	null
GSE146982_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HEPG2	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.909358
AB-71-CI37_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.205902
SARS-dORF6_0Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.12458
BRD-K85985071_E3380_SKB_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ATF2	ENCODE Transcription Factor Targets	1.0	null
CI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.92151
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
FB-66-UU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.70274
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.973633
IA-27-CK10_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.620818
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43865
GSE234289_4_v_0_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
E2F6_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	10.0
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09721
PMC8684775-CTM2-11-e640-s002.xlsx-Sheet1-Table_S3_MAF_file_of_the_CCS_samples_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
CEP192	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.13306
ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.09262
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.70487
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.853387
GTEX-SNMC-0226-SM-4DM6F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19085
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K07859598_GW-5074_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XYKS-1626-SM-4BRUQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25809
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LS-01A-22R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE199921_1_v_0_romidepsin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Duchenne muscular dystrophy (DMD)_Extraocular muscle_GSE1472	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.46905
GTEX-UPK5-1426-SM-4JBHH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.976412
GSE201042_2_v_3_ptpmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K04546108_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_6083_KD_UBE2I_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
UK 383367	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.69
CRCGN010_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.46106
Perinuclear endoplasmic reticulum membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.8
BRD-K67868012_PI-103_MCF10A_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IO-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DB-40-HA40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.231515
CBX3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4975902-12864_2016_2842_MOESM12_ESM.xlsx-targets_of_IRF8_in_NSCLC-COX7C_IRF8	Rummagene Transcription Factor Associations 2026	1.0	null
POU5F1-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-0011-R3B-SM-4AT6E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899211
IZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.4807
m2 part of substantia nigra compacta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41554
AF-80-GK24_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.221299
RAB18	Pathway Commons Protein-Protein Interactions	1.0	null
18535662-TableS1a	GeneSigDB Published Gene Signatures	1.0	null
TRIM24	Pathway Commons Protein-Protein Interactions	1.0	null
MCM2	Pathway Commons Protein-Protein Interactions	1.0	null
corl23	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.739
felbinac-4639	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
LC-40-KC29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.366428
PMC12271601-mmc2.xlsx-OUT_cells_03-Gene_Symbol_TCF23	Rummagene Transcription Factor Associations 2026	1.0	null
U2OS	CCLE Cell Line Gene CNV Profiles	1.0	2.09611
TYK-NU.CP-R	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01341
FF-28-ES17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.750587
SIX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE115542_5_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S4P3-1626-SM-3K2AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24977
GABPA_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUN_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10319804-41467_2023_38747_MOESM10_ESM.xlsx-circARID1A_KD_genes_up-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Learning Disorders	CTD Gene-Disease Associations	1.0	1.19113
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ME-31-RM40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.14623
GSE110178_5_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QESD-2026-SM-447BI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10983
MF-81-RJ18_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.220692
USF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K31013025	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3049
dactinomycin_mus musculus_gpl6246_gse21233	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
colchicine-3213	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KCNA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93312
BRD-K43025624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06905
CRCGN011_HEPG2_24H:P11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.55825
GSE217776,GSE217829_1_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXD4L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32823
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.57591
GSE160817_5_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GNAS	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K14821540_FCCP_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.865719
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LC-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
levonorgestrel-4269	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K28314528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.339
BRD-K33720394_(S)-1,1-dimethyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid JAS07_00S_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
17616640-TableS3	GeneSigDB Published Gene Signatures	1.0	null
H3K4me1_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K85697068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30747
Flocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41453
parataenial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22752
Prostate adenocarcinoma_PRAD_TCGA-HC-8258-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148066,GSE157787_8_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K53308430_-666_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-RWS6-1326-SM-47JXB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938145
Perturb_6038_KD_MPHOSPH10_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE154069_2_v_4_satb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AB-35-RU30_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.354513
AOB, mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10681
HCC1954	CCLE Cell Line Gene CNV Profiles	1.0	1.42906
BE-38-UW72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.394551
POLR2AphosphoS5_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K21718444_KW-2449_HEPG2_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K23478508_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GC-54-IZ89_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.204866
SIX5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFJO-0008-SM-4LVN7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837835
neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072134
GTEX-P44H-0426-SM-2XCEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.04242
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE166317_3_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.30507
subcuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.906802
endosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
BRD-K11663430_-666_ASC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ELF1_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YT-0326-SM-32PKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.93692
JD-44-KF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.850176
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.7149
CRCGN017_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.09376
GSE141453,GSE141454_0_v_4_card11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T8EM-1026-SM-3DB7M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32784
URGCP	Pathway Commons Protein-Protein Interactions	1.0	null
hypoglossal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.86376
GTEX-VJYA-0726-SM-4KL1T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.981901
GSE157684,GSE173391_0_v_1_rgcc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AE-36-GL26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.258256
PML_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SJXC-0526-SM-2XCFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.61134
EP300_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158197_5_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE228727_2_v_1_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5081
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15848
GSE216043_10_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K24377650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.58168
GTEX-V1D1-2026-SM-3GAF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47779
lateral part of r3B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02883
DD-15-VH74_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.384422
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OZ-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K79me1_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K83115645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00389
Lung squamous cell carcinoma_LUSC_TCGA-85-A4JC-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WHSE-3126-SM-3P5ZI	GTEx Tissue Sample Gene Expression Profiles	1.0	3.70135
BRD-K62418408	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06426
ZWILCH	Pathway Commons Protein-Protein Interactions	1.0	null
ZB-28-SS80_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.299869
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A8O8-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SB-29-ZH97_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.525551
BRD-K37656403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04606
trafficking	GeneRIF Biological Term Annotations	1.0	null
EIF2B2	Pathway Commons Protein-Protein Interactions	1.0	null
ETS1	ENCODE Transcription Factor Targets	1.0	null
GSE186440,GSE186443_0_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K48516290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0751
BRD-K06330738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02416
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_GSC-Unnamed_3_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70K-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STX18	Pathway Commons Protein-Protein Interactions	1.0	null
GSE153757,GSE153758_1_v_3_ftsj1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:E14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.8594
r3 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34953
Neoplasm Metastasis	DisGeNET Gene-Phenotype Associations	1.0	null
CRCGN016_MCF10A.WT.HP_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.31655
STX4	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-U4B1-1926-SM-3DB9E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839976
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49666
BRD-K18190982_COT-10b_HT29_24.0_h_44.4_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE111247_14_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0672
CRCGN013_HEPG2_24H:M05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.05836
GNAI2	Pathway Commons Protein-Protein Interactions	1.0	null
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OC-71-BZ81_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.571538
BRD-K29415052_NVP-BGT226_HEPG2_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SW1783	CCLE Cell Line Gene Expression Profiles	1.0	1.75295
BCOR-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GA-01-EO66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.259897
BRD-K15563106_-666_MCF7_24.0_h_177.6_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13544
BRD-A06352508_SB 218078_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A89Z-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ANXA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26342
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SMC2	Pathway Commons Protein-Protein Interactions	1.0	null
RPMI-7951	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.006
ATP6V0C	Pathway Commons Protein-Protein Interactions	1.0	null
Schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.055
buspirone-1282	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_6075_KD_SUV39H2_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-WVLH-3026-SM-3MJG9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972066
EPHA2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE127970_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SCAMP2	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN016_MCF10A.WT.HP_24H:E21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1891
BRD-K17140735_-666_OV7_6.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K15779027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29592
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.181
GTEX-Q2AG-0426-SM-2S1PU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.955671
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10524
H3K79me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.21269
MAPK8	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K95048194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.10323
AA-44-BX20_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.309042
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Central Neuroblastoma	DisGeNET Gene-Disease Associations	1.0	null
BRD-A24223049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69489
hsa-miR-4682	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12369
ZNF263	ENCODE Transcription Factor Targets	1.0	null
LIN7C	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_1564_KO_Tnfaip3_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.4792
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.920883
ATF3	ENCODE Transcription Factor Targets	1.0	null
BRD-K83090041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05517
cloperastine-4271	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-U64521890_XMD16-144_MCF10A_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K56751279_Y-39983_HT29_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.915453
CEM-C1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.094
BRD-K87383650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1056
BRD-K85284710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65866
WC-09-GD62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.474305
BRD-K13810148_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BE-36-XE09_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.270513
pterigoid muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72858
CRCGN016_MCF10A.TP53.M_24H:A18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.80407
CRCGN009_HEPG2_24H:H03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.52223
BRD-K84199148	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56506
BRD-K82910696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37792
GSE155031_5_v_0_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K53932786_2-Dichloromethyl-4-ethylsulfanyl-6-phenyl-[1,3,5]triazine MLS-0208612.0001_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-SNMC-1426-SM-2XCFM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.20807
BRD-K47467075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49685
ZBTB33	ENCODE Transcription Factor Targets	1.0	null
GSE146982_0_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE211931_2_v_3_ncoa4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GATA1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AA-46-GL76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.529934
BRD-M86331534_BJM-ctd2-9_HT29_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN008_HEPG2_24H:G24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.66955
CTCF_GM12872_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PA-70-ZC89_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.234568
BRD-K58772419_AZD-6482_MCF10A_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE118794_0_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VPS51	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ME-60-RF56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.208793
RAP2B	Pathway Commons Protein-Protein Interactions	1.0	null
DA-54-NN76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.298592
488395315_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.14344
ETS1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BD-50-HU68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.242239
BF-94-CQ58_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.343251
BRD-K80413110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63576
BRD-K41206520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.27925
CRCGN012_HEPG2_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.45055
neuroblastoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.712549
BCL3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PANC0813	CCLE Cell Line Gene Expression Profiles	-1.0	-2.04845
MCAD_KO_GDS4546_422_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K73678117	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05565
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14494
GSE210101,GSE210114_11_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
bumetanide-7440	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
AP1G1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE143212_0_v_3_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
integral component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.389296
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5259-01A-31R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chrX_49062789_G_A_b38	GTEx eQTL 2025	1.0	1.76619
AC-10-JK64_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.261104
ATP6V1D	Pathway Commons Protein-Protein Interactions	1.0	null
FADU	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.3821
GSE196835_0_v_1_ddx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.7845
17660535-TableS4a	GeneSigDB Published Gene Signatures	1.0	null
GSE196540,GSE196542_2_v_0_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-U70626184_BI-2536_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
amygdaloid complex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.3379
Perinuclear region of cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.741
carboxylic acid transport	GO Biological Process Annotations 2015	1.0	null
GTEX-QCQG-0008-SM-48U2G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968884
BRD-K83972459_JWE-035_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15725
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.4019
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4225-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SU-DHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16851
BRD-K92640680	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09496
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L7-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE236262_2_v_1_trim28_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-73-4658-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K58772419_AZD-6482_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-U60236422_WH-4-025_MCF10A_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HD-89-HC56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.327235
GSE93309_5_v_0_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
lysosome	LOCATE Predicted Protein Localization Annotations	1.0	null
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PML	ENCODE Transcription Factor Targets	1.0	null
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_1_BioID_ERM_proteome-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
AC-40-DU58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.3427
HS600T	CCLE Cell Line Gene Expression Profiles	1.0	1.53693
GC-54-IZ89_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.246176
DA-35-DU85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.15255
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KYSE-450	GDSC Cell Line Gene Expression Profiles	-1.0	-1.57317
TBC1D10A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6522
BRD-K26122955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17488
BRD-K44864058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21178
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1	ENCODE Transcription Factor Targets	1.0	null
GSE165647_2_v_3_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AB-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE185519_4_v_5_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908056
BRD-K56277358_MGCD-265_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Simian Acquired Immune Deficiency Syndrome_T lymphocyte_GSE4785	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.53933
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.07911
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07535
preoptic region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.97239
brain_3c	HPA Tissue Sample Gene Expression Profiles	1.0	1.67864
IQGAP1	Pathway Commons Protein-Protein Interactions	1.0	null
Thyroid	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.44157
RA-49-ZB08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.339151
NANOG-16518401-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
diphenhydramine-1871	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE179002_0_v_7_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
WB-82-EL69_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.87301
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T2IS-0008-SM-4DM75	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833509
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
presynapse	SynGO Synaptic Gene Annotations	1.0	null
GTEX-RM2N-0326-SM-48FD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26391
PLCD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09978
GSE114992,GSE114993_0_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Oligospermia	CTD Gene-Disease Associations	1.0	1.04978
EOL1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	2.4412
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09115
AGK	Pathway Commons Protein-Protein Interactions	1.0	null
GSE217873_1_v_2_nusap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Prestwick-642-4594	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-T6MN-0011-R2A-SM-32QOW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87704
BRD-K42918627_GSK-2126458_A549_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AB-12-PP61_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.351335
tetrahydropalmatine	CTD Gene-Chemical Interactions	1.0	null
NEC8	GDSC Cell Line Gene Expression Profiles	-1.0	-1.44585
CRCGN012_HEPG2_24H:G03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.86035
BRD-K41327620	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60463
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.935302
inferolateral temporal cortex (area TEv, area 20)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.36509
CTCF_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC3296722-pone.0032481.s009.xlsx-Sheet_1_MSC_vs_references-Gene_Symbol_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.121
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_name_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE208254_4_v_2_irf8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SPTBN1	Pathway Commons Protein-Protein Interactions	1.0	null
TAF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BE-42-IC00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.498999
schneider-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.17181
ME-54-JY76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.301157
KC-95-ZW49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.378151
SACM1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15189
Prostate adenocarcinoma_PRAD_TCGA-G9-6362-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
17638893-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
BRD-K19962165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.40162
DC-47-KV62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.207637
RPS23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15967
CB-32-EI69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.233983
FB-75-YG01_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.287597
SKBR3	CCLE Cell Line Gene CNV Profiles	1.0	1.50872
REST	ENCODE Transcription Factor Targets	1.0	null
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
temporal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84564
intermediate part of r8B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21049
CI-1040	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05976
PMC12234789-41467_2025_61560_MOESM3_ESM.xlsx-Supplementary_data_1-Only_YY1_IP-MS_YY1	Rummagene Transcription Factor Associations 2026	1.0	null
NFATC1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-U88459701_atorvastatin_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FB-75-YG01_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.528368
BRD-K03254663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82551
FD-62-ZB67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.575207
H3K9me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6496-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARHGAP35	Pathway Commons Protein-Protein Interactions	1.0	null
tinidazole-3813	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-X3Y1-0426-SM-3P5Z4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828019
SHSY5Y	DepMap CRISPR Gene Dependency	1.0	3.56389
BRD-U64521890_XMD16-144_MCF10A_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Pituitary	GTEx Tissue Gene Expression Profiles 2023	1.0	1.63482
posteromedial visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08552
CRCGN016_MCF10A.TP53.M_24H:E21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.93497
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.965154
therapeutic	GeneRIF Biological Term Annotations	1.0	null
PHA-00745360-3824	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-P4PP-1026-SM-3NM9O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74205
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056326
BE-66-UB12_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.418854
CA-63-LW25_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.216394
GTEX-OHPL-0326-SM-33HC8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856524
BRD-K13094524_PFI-1_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-RU72-0008-SM-46MV8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930496
HEC1B	DepMap CRISPR Gene Dependency	1.0	3.44287
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K09951645_dabrafenib_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_6092_KD_YY2_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
dosulepin-5986	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
substantia nigra compacta, isthmic part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02883
cisplatin_mus musculus_gpl339_gse6206	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K00378498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12577
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Parasubiculum, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47398
PIK3C2B	Pathway Commons Protein-Protein Interactions	1.0	null
GB-06-BA49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.24285
anterior (rostral) cingulate (medial prefrontal) cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.35827
CRCGN017_MCF10A.TP53.M_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.0518
BC-53-HT63_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.479513
GTEX-V1D1-2426-SM-3GAER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1133
r6 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42699
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IJ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE195559_2_v_7_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K69569958	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25484
dorsolateral prefrontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11954
SNPH	Pathway Commons Protein-Protein Interactions	1.0	null
BIN1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN016_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	10.0
GTEX-Q2AI-1726-SM-2S1PZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853863
Perturb_5861_KD_H3f3a_SRP133189	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.68663
GTEX-RVPV-0008-SM-47JYW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76179
BRD-K49075727_nintedanib_LNCAP_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CSNK1A1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7617064-EMS151900-supplement-Extended_Data_Figure_5_Source_Data.xlsx-CLC_D9_DEG-Logfold_change_threshold_1_0_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
NFKBIE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11494
VZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11631
HEY1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9889
TE-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.121
BRD-K68007270_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KA-29-AB08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.51136
AA-46-GL76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.542779
GSE164874_5_v_7_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
layer 4 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03716
primary visual cortex (striate cortex, area V1/17)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.928895
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1272
Lingula (I), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74917
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAP1A	Pathway Commons Protein-Protein Interactions	1.0	null
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.3805
BRD-K26018295	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25646
BRD-K13087600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26468
H3K79me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K81418486_vorinostat_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
IZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.12917
H3K79me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ELF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064206
single-organism transport	GO Biological Process Annotations 2015	1.0	null
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02718
BRD-K02675272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3407
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K79me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
chlorpromazine-1055	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-Q2AG-0526-SM-2S1PW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1372
VTA1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K37912617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76027
Perturb_6064_KD_RPF1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
AF-80-GK24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.486931
ETS1	ChEA Transcription Factor Targets	1.0	null
GTEX-X261-0011-R8A-SM-4E3I5	GTEx Tissue Sample Gene Expression Profiles	1.0	2.25981
BRD-K48102350	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71327
GSE216273,GSE216292_14_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7665
GSE198380_0_v_1_phgdh_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE166783_3_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.56522
Lung squamous cell carcinoma_LUSC_TCGA-77-7140-01A-41R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ME-54-JY76_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.251407
Perturb_11634_KD_IFNA17_SRP113334	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.93688
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07667
COV434	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.51917
GSE116930,GSE116935_1_v_6_hes7_human	RummaGEO Gene Perturbation Signatures	1.0	null
RBX1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K80858297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97238
GSE174701_5_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GF-35-IT27_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.326525
BRD-K21203629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16445
minaprine-4230	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE213588_8_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A.WT.HP_24H:A18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.04717
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RA-89-RR01_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.571298
LF-85-QP07_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.319116
FA-88-II68_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.347531
GSE193258,GSE193259_9_v_12_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Rectum adenocarcinoma_READ_TCGA-DY-A1DD-01A-21R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PSDG-0226-SM-33HC1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24973
GSE178255_1_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-302a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.19434
GSE165704_0_v_1_rif1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10279693-41389_2023_477_MOESM2_ESM.xlsx-N_MYC-WDR5-DMSO-overlap_peaks_a-Unnamed_15_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
RAP1GDS1	Pathway Commons Protein-Protein Interactions	1.0	null
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.48658
Prostate adenocarcinoma_PRAD_TCGA-G9-6347-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A34842997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26935
BE-04-AN21_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.486825
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1155	GDSC Cell Line Gene Expression Profiles	1.0	1.91219
BRD-K68174511_torin-2_HEPG2_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-SNMC-1226-SM-2XCFP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.00047
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21022
BRD-K94777797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.88826
SIX5_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4430-01A-02R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K81418486_vorinostat_HCT116_6.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SK23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.67457
GTEX-O5YT-1026-SM-3MJGF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22041
CD-26-MB82_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.270949
GTEX-O5YT-0008-SM-4E3IQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905051
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157F_vs_MSX1-Gene_id_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08146
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146247_0_v_1_sirt7_human	RummaGEO Gene Perturbation Signatures	1.0	null
LF-94-HB11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.591052
BRD-K99172965	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23248
Adrenocortical carcinoma_ACC_TCGA-OR-A5KV-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RD-92-QT24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.799415
RIPK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27564
CRCGN008_HEPG2_24H:L15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.64855
BRD-K70401845_erlotinib_MCF10A_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SEPT14	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K64642496_-666_MCF7_24.0_h_40.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PLEKHA7	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
HS 852.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.28889
BRD-K32398298_alprazolam_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN015_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.90505
TA-34-CK62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.281404
posterior (caudal) superior temporal cortex (area 22c)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11954
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FC-05-LX47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.575009
PMC6357748-aau9223_Table_S1.xlsx-CD4_T_-_LPS-Unnamed_0_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Inflammation	CTD Gene-Disease Associations	1.0	1.10977
CRCGN016_MCF10A.TP53.M_24H:N01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0025
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC4823830-ncomms11171-s3.xlsx-high_in_shRNA_GATA3-GeneSymbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.892228
DC-47-KV62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.685154
BRD-K31820800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66693
GSE195786_0_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FF-54-JC89_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.502291
RBM8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82079
GSE219195_1_v_3_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4434	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GTEX-RN64-0326-SM-2TC5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19085
GSE142210_9_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
17683608-TableS3	GeneSigDB Published Gene Signatures	1.0	null
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K46149455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33534
HE-29-OW54_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.263381
Adrenocortical carcinoma_ACC_TCGA-OR-A5L9-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K21470524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48956
VAMP8	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_5997_KD_C5orf41_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
STAT1-19122651-HELAS3-HUMAN-CERVICALCANCER	ChEA Transcription Factor Targets 2022	1.0	null
GATA1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K11267252_CH5424802_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE186440,GSE186443_4_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
caco2	HPA Cell Line Gene Expression Profiles	-1.0	-1.06753
VMRC-MELG	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.28568
CRCGN015_MCF10A_48H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.54097
BRD-K73261812_-666_PC3_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE88819_0_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K79me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.95073
GABPA	ENCODE Transcription Factor Targets	1.0	null
GSE160373_6_v_2_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044145
GTEX-S341-1726-SM-3K2AK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.97701
TD-69-UA90_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.347338
GTEX-VJWN-0126-SM-3GIK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887017
BRD-A76490030_2-[(chloroacetyl)(3,4-dimethylphenyl)amino]-N-cyclohexyl-2-pyridin-3-ylacetamide_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CDK19_knockdown_164_GSE38061	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.54139
BA-84-WN26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.591547
ZBTB33_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATP6V1C2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K49328571_dasatinib_A375_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE123958,GSE123959_0_v_1_mta1_human	RummaGEO Gene Perturbation Signatures	1.0	null
AB-30-CR11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.00671
CB-36-QH71_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.331121
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
BRD-K17300786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94629
wortmannin-1081	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE95077_5_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
EB-67-WB79_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.322396
GTEX-PSDG-0626-SM-2S1OE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00983
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.5412
AA-59-HG56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.421769
OV56	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.826716
epididymis	HPA Tissue Protein Expression Profiles	1.0	1.10186
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
I-II	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.38879
CRCGN015_MCF10A.TP53.M_24H:E10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1818
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
valdecoxib-6408	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
GTEX-WHPG-2226-SM-3NMBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12189
Fetal_Brain_Female	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.838881
BRD-K99447506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.25958
VPS29	Pathway Commons Protein-Protein Interactions	1.0	null
NOP53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5078
GTEX-OXRP-0926-SM-48TC1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62576
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.834335
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.35947
GSE178907_4_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CE-18-AP15_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.456107
Lateral reticular nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48283
salivarygland	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.855935
GTEX-UPJH-0226-SM-3GADV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26253
CRCGN015_MCF10A.WT.HP_24H:F17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.88384
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.944468
BRD-K44856541	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16452
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Periventricular zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29119
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.620399
MAP2K4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59934
BRD-K58846294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06736
OC-10-FB51_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.309399
Perturb_6018_KD_GLTSCR2_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
496100636_FWM_probable Alzheimer's disease_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.94951
GSE142210_11_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K12343256_trametinib_MCF10A_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.5973
ciclopirox-2456	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K58643762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34998
BRD-K29415052_NVP-BGT226_HEPG2_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CHMP2A	Pathway Commons Protein-Protein Interactions	1.0	null
fasciola cinerea	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18454
GSE127790_9_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
FGD4	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V1D1-0526-SM-4JBGW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.859264
BRD-K09951645_dabrafenib_A375_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE179036_1_v_0_trim24_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K68540120	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08869
DU4475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.972306
SCOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42809
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UJMC-0008-SM-4IHKK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863868
BRD-K39520573_GW 5074_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CDK8_knockdown_163_GSE38061	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.19981
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.834632
CRCGN010_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.08125
CREB1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lorglumide-3079	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2AphosphoS5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA3_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UTHO-1026-SM-3GAF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.959669
GOLIM4	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-7141-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WB-82-EL69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.201465
BRD-K05870596_XMD-1499_PC3_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
D-423MG	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.0075
BRD-K01614657_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K01436366_XMD-1150_MCF10A_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HSPA12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26514
BRD-A44990218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75241
T173	CCLE Cell Line Gene Expression Profiles	1.0	1.62099
FB-39-CW59_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.246831
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.60819
GTEX-QVJO-0126-SM-3GIK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44692
GSE179002_4_v_7_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE130715_1_v_0_budesonide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K31844308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.23477
gata3_21892208_mda_mb_231_gof_human_gpl570_gds4080	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.027835
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TM-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.922
BRD-K73387470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42209
BRD-K12502280_TG-101348_MCF10A_3_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
L-glutamate import	GO Biological Process Annotations 2025	1.0	null
medial superior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59188
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K77908580_entinostat_HCC515_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_6010_KD_EBNA1BP2_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
mantle zone of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18251
BCL3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_5916_KD_HNRNPK_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-14.6196
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.69094
GSE127790_11_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.9403
inner SZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.888289
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I0-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K92513859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1041
JE-04-LS32_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.23233
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.22864
BC-33-BM51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.421085
EA-93-KT88_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.628678
OF-19-JH77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.381929
GSE216273,GSE216292_14_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pituitary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.64496
bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.075523
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16042
GSE239844_1_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
tamoxifen-143	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
496100573_HIP_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2027
CLTA	Pathway Commons Protein-Protein Interactions	1.0	null
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17547
VA-48-RJ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.332408
TE-87-FM14_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.291735
GATA3	ENCODE Transcription Factor Targets	1.0	null
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SE-15-AV21_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.316756
BRD-K81206010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5039
GSE171292_1_v_0_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AA-56-JY17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.394141
HS675T	CCLE Cell Line Gene Expression Profiles	1.0	1.41901
WD-62-UB45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.265451
BHLHE40_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
smoothmuscle_8b	HPA Tissue Sample Gene Expression Profiles	1.0	2.43985
BRD-U64521890_XMD16-144_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-R45C-0008-SM-48FF2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13088
DM3	CCLE Cell Line Gene Expression Profiles	1.0	1.49886
GSE88819_3_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.86807
GTEX-PLZ4-0726-SM-2TC6Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16305
BRD-K27008344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67528
GSE248045,GSE248046_6_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Penis_Foreskin_Fibroblast_Primary_Cells_skin02	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.926676
bone cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.335233
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.57345
GSE213588_10_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U4B1-1626-SM-3DB8N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.89461
OB-65-AI50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.200268
sulfaquinoxaline-2528	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K79me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K64890080_BI-2536_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE245270_2_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061559
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYC_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
ANXA4	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-645	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
BRD-K94845132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5744
GSE130956_0_v_3_icaritin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CA-42-YI34_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.707119
ZNF300	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50986
CB-06-FE89_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.228004
BRD-K30677119_PP-30_HT29_24.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LD-48-CY61_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.598254
USF1	ENCODE Transcription Factor Targets	1.0	null
POLR2A_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2ND-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE176008_0_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r3BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34953
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsal raphe nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24467
HPGDS-In1	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.28
GSE216043_10_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K04801023_SAR-245408_PC3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE131798,GSE131804_2_v_0_igf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
roof plate of p2 (epithalamic roofplate)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73778
BRD-K79259477_KIN001-265_A375_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE135352_2_v_4_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZI-0726-SM-2XCEI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826863
NC-06-IT89_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.303007
GSE256181_2_v_0_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE198165,GSE198166_8_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_10_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202434,GSE202438_10_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HELA	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.858683
GTEX-U8XE-1226-SM-4E3HN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98418
BRD-U51024685_HG-6-64-01_MCF10A_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN016_MCF10A.WT.HP_24H:L23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.48028
neuroblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.616586
GTEX-QMRM-0626-SM-447BQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865937
GTEX-XYKS-0926-SM-4BRVG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835878
CB-87-RB49_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.225124
BA-46-YF32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.307276
BRD-K89650689	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63223
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.368
CRCGN017_MCF10A.WT.HP_24H:L21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6332
ZBTB32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00241
FC-22-VC55_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.6827
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.929899
Golgi-associated vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.972
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HC-11-RK51_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.294256
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H522	GDSC Cell Line Gene Expression Profiles	1.0	1.79358
GTEX-RVPV-0526-SM-47JYL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838272
CTCF_cardiac fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3922-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Perturb_11645_KD_LNX2_SRP113334	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.31275
DD-30-SX80_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.745812
CRCGN016_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.51916
NSF	Pathway Commons Protein-Protein Interactions	1.0	null
GSE57871_6_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
FADU	CCLE Cell Line Gene CNV Profiles	1.0	1.91913
EJM	DepMap CRISPR Gene Dependency	1.0	13.3955
BRD-K96627018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38495
BRD-K09328667	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18573
superficial stratum of m1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00183
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6793-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K31706415_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
42-MG-BA	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.93416
RAC1	Pathway Commons Protein-Protein Interactions	1.0	null
DST	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
FB-56-IR20_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.259758
GSE174701_1_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052816
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hindbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.082677
WERIRB1	DepMap CRISPR Gene Dependency	1.0	2.28696
GSE119564_1_v_3_zfp217_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE120413,GSE120447_3_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OOBK-0008-SM-3NB27	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23962
ME-73-FK70_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.25675
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K12787259_CX-5461_A375_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GATA2	ENCODE Transcription Factor Targets	1.0	null
USE1	Pathway Commons Protein-Protein Interactions	1.0	null
DA-32-QL71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.220588
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
CF-61-EH59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.343179
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K82868643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27969
T-24	GDSC Cell Line Gene Expression Profiles	1.0	1.43197
MV-4-11	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.31773
CRCGN014_HEPG2_24H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.80475
BRD-K49328571_dasatinib_A375_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EGR1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_3H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.25387
LRCH4	Pathway Commons Protein-Protein Interactions	1.0	null
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.12711
BRD-K11630986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13658
S0-EE-YAXR_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.240685
Esophageal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.029
lateral ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.307528
Primary motor area, Layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03301
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WHSB-1326-SM-3LK6W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0851
DCTN3	Pathway Commons Protein-Protein Interactions	1.0	null
CEBPB_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S32W-1626-SM-4AD6G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982304
CRCGN008_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.2418
ZW10	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN017_MCF10A.WT.HP_24H:G12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5211
PRKDC	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K54420800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0242
brain	GeneRIF Biological Term Annotations	1.0	null
GTEX-P4PQ-0426-SM-3NMCI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888978
GSE226316_3_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K64890080_BI-2536_BT20_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K93747042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52836
AA-24-UO04_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.31974
fluvastatin-5290	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K93186184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.54785
ETS1-20019798-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A11154023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73894
BRD-K42918627_GSK-2126458_HEPG2_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_6055_KD_PTBP1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BB-77-QQ71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.610792
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
parafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.950123
BRD-K47801291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38289
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054846
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SB-74-OD45_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.340087
BRD-K50387473_XMD-892_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCIH1435_LUNG	CCLE Cell Line Proteomics	1.0	2.73656
NCIH1573	DepMap CRISPR Gene Dependency	1.0	2.51488
GA-04-JM33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.767208
PMC11242342-jcav15p4513s1.pdf-28-ZNF875_ZNF875	Rummagene Transcription Factor Associations 2026	1.0	null
GSE115364_0_v_1_idh3a_human	RummaGEO Gene Perturbation Signatures	1.0	null
GB-90-UG49_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.229954
DONSON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37215
BRD-K04005364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58423
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28366
OV7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.877578
ME-11-OJ38_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.303108
GTEX-R3RS-0126-SM-3GIJL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01269
BRD-K41220170_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PC-44-DH10_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.369226
8305C_THYROID	CCLE Cell Line Proteomics	1.0	4.88968
CP-320650-01-3825	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE184892_4_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:L23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2868
GTEX-QDVN-0226-SM-48TZ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47797
BRD-K56075657	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50172
TBX2-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
HuP-T3	GDSC Cell Line Gene Expression Profiles	-1.0	-1.5941
Malignant Glioma	DisGeNET Gene-Disease Associations	1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1321	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.14531
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
CE-15-YU05_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.527741
LC-12-VN85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.703181
GSE146982_3_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN012_HEPG2_24H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.43215
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.44352
UA-39-TN76_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.514462
BRD-K24496049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.13887
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
GTEX-Q2AG-2926-SM-2HMJ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06184
BRD-K43108627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.53686
GE-53-SM76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.276319
motor nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.91121
BRD-K36104357	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17955
KRBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28711
primary auditory cortex (core)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.0741
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LD-00-HM58_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.222575
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K54606188_(+)-JQ1_HA1E_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HC-18-NB46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.247348
NFATC1	ENCODE Transcription Factor Targets	1.0	null
XD-44-FJ34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.462435
Perturb_6100_KD_ZNF622_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
TAF1_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AC-55-XA97_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.269164
GW-8510-7080	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TAP2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE198165,GSE198166_7_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EXOC5	Pathway Commons Protein-Protein Interactions	1.0	null
t30-blood-rna_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.53173
olfactory bulb, principal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16292
GSE151782_4_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100638_FWM_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.61229
various	GeneRIF Biological Term Annotations	1.0	null
TC205	DepMap CRISPR Gene Dependency	1.0	3.19834
GSE147876,GSE147877_2_v_7_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CA-16-ZL71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.222912
DC-23-UM36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.298681
GTEX-QEG4-0426-SM-33HC3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.99176
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.95704
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10274
GSE180321_0_v_1_imperatorin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ioxaglic acid-2966	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K01436366_XMD-1150_BT20_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HB-54-ZC59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.296344
Perturb_6066_KD_RPS19BP1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
CRCGN015_HEPG2_48H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.12656
GTEX-QVJO-0011-R8A-SM-447C7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21376
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18372
HS 675.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.56445
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.925065
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K20526256_HG-14-10-04_A375_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K36me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RNF214	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.141
BRD-K39677043	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27989
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
parabigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4874
G402	DepMap CRISPR Gene Dependency	1.0	2.72525
CHST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46199
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.860896
BRD-K91866516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37023
CRCGN008_HEPG2_24H:H03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4089
HD-51-KD29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.277828
ATP6V1C1	Pathway Commons Protein-Protein Interactions	1.0	null
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.4905
mantle zone of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15893
BRD-A24396574_celastrol_MCF10A_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-U61997977_WZ-4-145_MCF10A_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MAPRE1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K48188521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81412
BRD-K77908580_entinostat_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RAB43	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K54606188_(+)-JQ1_A549_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
modulate	GeneRIF Biological Term Annotations	1.0	null
endometrium_5a	HPA Tissue Sample Gene Expression Profiles	1.0	0.851207
BA-84-TD72_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.372592
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
BRD-K23316938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2848
POLR2A_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FE-37-OL13_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.666926
GSE112860_3_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9537523-41467_2022_33364_MOESM7_ESM.xlsx-scores_wilcoxon_1_MONTH_ORG-EN1_n_EN1	Rummagene Transcription Factor Associations 2026	1.0	null
N-acetyl-L-leucine-5683	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IC-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CREB1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.19087
membrane	GO Cellular Component Annotations 2015	1.0	null
nalidixic acid-3668	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.966711
BRD-K12502280_TG101348_MCF7_24.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K92544320	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.46108
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.14846
BE-16-VM54_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.298887
GTEX-RWS6-2126-SM-2XCAV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50925
CA46	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.937708
JHOS2	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59447
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endosomal part	GO Cellular Component Annotations 2015	1.0	null
GSE96641_5_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K59469039_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE196259_2_v_3_gcm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DF-92-CF17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.33534
MDBK cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.867
GTEX-T5JW-1626-SM-3GADZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34022
Perturb_17686_OE_HSD17B1_SRP366068	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.66773
CRCGN015_MCF10A.TP53.M_24H:I07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12815
PMC4090731-bjc2014262x1.xls-Sheet1-CaSig-HSF1_Positive_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11696420-41467_2024_55617_MOESM3_ESM.xlsx-Sheet1-Supplementary_Data_1_The_2495_differentially_expressed_genes_between_the_L3MBTL3_knockout_L3-KO4_or_L3-KO5_and_control_C_groups_of_SUM159PT_cells_L3MBTL3	Rummagene Transcription Factor Associations 2026	1.0	null
parvocellular part of r8LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64415
PA-TU-8902	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.878569
CRCGN017_MCF10A.TP53.M_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.61561
BRD-K21025364_NVP-TAE226_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hippocampus (hippocampal formation)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.89728
GSE158502,GSE158506_3_v_0_fat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
AC-41-IB85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.276789
CRCGN015_MCF10A.WT.HP_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.15503
DD-30-SX80_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.500828
ED-81-ZH14_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.258731
CHD3	Pathway Commons Protein-Protein Interactions	1.0	null
Breast - Mammary Tissue	GTEx Tissue Gene Expression Profiles 2023	1.0	2.88782
BRD-K50387473_XMD-892_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
IQGAP3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K25525067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.55823
BRD-K11267252_CH5424802_MCF7_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
USF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91812
PMC7455079-jciinsight-5-140380-s227.xlsx-Supp_Table_8-ILL1_T_Cells_FOXP3_FOXP3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6379364-41598_2018_37489_MOESM2_ESM.xlsx-Sheet2_DESeq_MSC_vs_fibroblast-Unnamed_1_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K86797399_pracinostat_HCC515_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
7185_RBM8A_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.20437
SMC3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YV-0426-SM-3LK66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05679
DD-68-ZP95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.268351
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K42960858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10341
NCIH650	DepMap CRISPR Gene Dependency	1.0	2.69742
Secondary motor area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10374
BRD-K03406345_azacitidine_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
GTEX-R3RS-0526-SM-3GADG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963808
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K04513994	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45263
SYNJ2BP	Pathway Commons Protein-Protein Interactions	1.0	null
TRIM28	Pathway Commons Protein-Protein Interactions	1.0	null
GC-08-VP20_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.60016
H3K4me1_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
496100637_FWM_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.87289
CRCGN009_HEPG2_24H:M19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.69
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.311
RKO-E6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.979223
VDR-23849224-CD4+-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-A34774643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28219
BRD-K56343971_vemurafenib_A375_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GTEX-NL3G-0008-SM-4E3JX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16256
BRD-K83972459_JWE-035_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCA-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.26778
BRD-K02708799_GSK-1059615_A375_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_11640_KD_ITCH_SRP113334	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.79876
OA-15-DB28_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.276746
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1149
BA-29-GH49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.206923
KB-17-PN92_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.245391
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4770-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN010_HEPG2_24H:M20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18296
GSE165122_0_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4088
BRD-K83972459_JWE-035_HA1E_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K72685049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76811
GTEX-V955-2426-SM-3GAEF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51245
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
YY1	ENCODE Transcription Factor Targets	1.0	null
GSE164874_5_v_14_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
OCT4-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
DD-61-DY35_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.221641
TMED10	Pathway Commons Protein-Protein Interactions	1.0	null
H3K79me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OCT4-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PRDM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90606
POU2F2_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-IS-A3K7-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A45498368_WYE-125132_MCF10A_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WH7G-0826-SM-4LVMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08775
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
PMC5404927-elife-24463-supp1.xlsx-1b_ERM_proteome-Gene_names_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XQ8I-1926-SM-4BOOK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.951406
RANBP17	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-1592-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K36363294_I-BET151_HA1E_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE147893,GSE147897_2_v_1_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE151612_4_v_2_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KD	DepMap CRISPR Gene Dependency	1.0	2.09213
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.42675
BRD-K08799216_pelitinib_MCF10A_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
STAT3	Pathway Commons Protein-Protein Interactions	1.0	null
CCNT2	ENCODE Transcription Factor Targets	1.0	null
urapidil-3078	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K68119260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03631
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
GSE201042_6_v_1_ptpmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Actinic keratosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.28
CTCF_GM12865_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IST1	Pathway Commons Protein-Protein Interactions	1.0	null
SNX3	Pathway Commons Protein-Protein Interactions	1.0	null
Stomach	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.649431
VZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.35657
PE/CA-PJ15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11827
CRCGN017_MCF10A.TP53.M_24H:N03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.96405
BRD-K05804044_AZ-628_A375_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE226091,GSE226092_0_v_4_sall1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-DX-A7ET-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE139239_2_v_6_ddr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K84595254_-666_ASC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K99252563_QL-XII-47_MCF10A_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
substantianigra	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.13307
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.835224
lymphoid cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE135400_1_v_0_kdm1b_human	RummaGEO Gene Perturbation Signatures	1.0	null
EA-40-KQ08_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.340751
CCNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06694
BRD-K05804044_AZ-628_A375_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K97365803_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.09267
VAC14	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6369-01A-21R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Piriform-amygdalar area, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43845
GSE174735_4_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.06202
BRD-K33045404_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TFCP2L1	ChEA Transcription Factor Targets	1.0	null
BRD-K83972459_JWE-035_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MT-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.835
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN012_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.33582
superficial stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.84977
BRD-A27080191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36633
LD-39-FL02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.561401
GSE96991,GSE97117_4_v_2_il11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4483	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
BRD-A04231641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02983
DB-40-HA40_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.202855
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.839739
hsa-miR-4708-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
BRD-K60782883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58317
GTEX-X585-3026-SM-46MWF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08287
BRD-K67844266_MLN4924_HA1E_24.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ANXA6	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_15828_OE_Nrf2_SRP291726	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	16.7416
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.559488
GSE211126_1_v_4_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DE-01-HO61_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.208067
BLOC1S5	Pathway Commons Protein-Protein Interactions	1.0	null
EGR1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-QC-A6FX-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K54606188_(+)-JQ1_HCC515_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RERF-LC-MS	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.06985
GTEX-OOBJ-0008-SM-3NB26	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23651
CTCF_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEY	DepMap CRISPR Gene Dependency	1.0	2.2953
BRD-K21680192_mitoxantrone_MCF10A_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K92825272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.28957
GSE245418_0_v_2_cd109_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K99380757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44158
valproic acid-23	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE175787_5_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_2_TurboID_10m_ERM_proteome-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.581719
GSE123502,GSE123504_1_v_0_chd4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AE-14-NN26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.312581
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CHD7	ENCODE Transcription Factor Targets	1.0	null
SEPT10	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN012_HEPG2_24H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.44553
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.28961
layer 2 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19369
CC-61-HH09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.444953
ANKRD11	Pathway Commons Protein-Protein Interactions	1.0	null
TTF2-22483619-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K15099225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.74454
WA-43-MP01_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.21238
AF-67-LZ82_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.218862
CRCGN015_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	10.0
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE149075_1_v_4_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01377
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K81418486_vorinostat_HT29_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K36363294_I-BET151_HCC515_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BC-84-BQ58_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.665196
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.4826
PSMB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0067815
cefalonium-2921	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H4K20me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07403
p1 part of the substantia nigra compacta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45247
LTBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30566
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.74663
bonemarrow	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.63175
POLR2AphosphoS2_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-1.23482
ML1	CCLE Cell Line Gene Expression Profiles	1.0	1.55573
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.499735
MA-88-CA03_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.375135
KA-71-CQ35_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.26514
CRCGN011_HEPG2_24H:F02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.04335
496100503_HIP_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09761
VPS36	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K79494396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56231
CA-75-HA22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.330119
GSE198794_0_v_1_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
Primary somatosensory area, upper limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.24943
GSE152699,GSE152723_0_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A8HY-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BJAB cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.864
350_ANLN_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.77359
S462	DepMap CRISPR Gene Dependency	1.0	2.12105
MCF7_SB431542_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0143687
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
possibly	GeneRIF Biological Term Annotations	1.0	null
BRD-K70992537	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22242
GTEX-WHSE-0011-R1A-SM-3P5ZK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76535
hsa-miR-423-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
L-glutamate import	GO Biological Process Annotations 2023	1.0	null
BRD-K01436366_XMD-1150_MCF7_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EB-67-WB79_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.340575
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
OVK-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNX13	Pathway Commons Protein-Protein Interactions	1.0	null
CLOCK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3577
GSE157894_2_v_0_cystine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN012_HEPG2_24H:J21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.01547
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K74116035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18819
FOXA1	ENCODE Transcription Factor Targets	1.0	null
CRCGN016_MCF10A.TP53.M_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.00555
GSE228181_3_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
endometrium_8b	HPA Tissue Sample Gene Expression Profiles	1.0	1.04741
BRD-K09951645_dabrafenib_A375_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K33760911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.13494
Pancreatic adenocarcinoma_PAAD_TCGA-YH-A8SY-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CB-32-EI69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.236743
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.829841
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28387
tumorigenesis	GeneRIF Biological Term Annotations	1.0	null
superficial stratum of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.64237
BRD-K17675924	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52151
MDAMB175VII	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.669662
JA-95-PQ25_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.39984
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78661
BRD-K72773309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01827
AC-30-XU83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.486921
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.4321
CTCF_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5175-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K90655269	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2863
CRCGN016_MCF10A.WT.HP_24H:A22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.24722
GTEX-OOBK-2626-SM-2HMKY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856363
BRD-K05251963	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08914
HS 940.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.92761
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lingula (I)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3768
CRCGN017_MCF10A.TP53.M_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.81413
Frontal pole, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14677
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047121
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.32221
AA-48-XT80_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.390372
H3K36me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN013_HEPG2_24H:D08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.73114
KE39	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57844
K562	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.04514
LRP10	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K04462989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49656
GSE201217_4_v_6_usf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K13044705	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74683
CRCGN012_HEPG2_24H:G04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.51825
CRCGN015_MCF10A.TP53.M_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.38494
GTEX-O5YT-0426-SM-3MJHD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01036
SFT2D3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K01436366_XMD-1150_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K78431006_crizotinib_PC3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE233647_4_v_5_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE196343_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Wsunhl	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.799
hsa-miR-520c-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
BRD-K81418486_vorinostat_HCC515_24.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K12502280_TG-101348_BT20_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SCP2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K40175214_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HU-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ALVA31	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.1752
endosome membrane	GO Cellular Component Annotations 2015	1.0	null
estradiol-988	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K86454955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76011
BRD-A86550573	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09981
BRD-K13665914_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EIF2B3	Pathway Commons Protein-Protein Interactions	1.0	null
NUP50	Pathway Commons Protein-Protein Interactions	1.0	null
EXOC6	Pathway Commons Protein-Protein Interactions	1.0	null
ULK3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K88510285_B675700.cdx_JHUEM2_6.0_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
WASL	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K54606188_(+)-JQ1_HCC515_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K53417444_OTSSP167_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K13309514	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24131
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BA-52-FW03_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.266915
FE-29-XM40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.415459
NCI-H2369	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.2303
RAD21_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.1033
terconazole-2844	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02719
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.19146
CB-16-SY72_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.21906
Substantia nigra, compact part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48626
BRD-K64890080_BI-2536_MCF10A_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
OSBPL10	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-6597-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATP6V1G1	Pathway Commons Protein-Protein Interactions	1.0	null
r8 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42552
PMC10592471-NIHMS1912771-supplement-4.xlsx-D-HEP3_UP_AA_UP-AA_UP_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
localization	GO Biological Process Annotations 2015	1.0	null
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.060637
Prenylated rab acceptor PRA1	InterPro Predicted Protein Domain Annotations	1.0	null
Ganglion	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.031
BRD-K79090631_CGP-60474_MCF7_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K91843292	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23031
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16441
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Defactinib	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.46
Lung adenocarcinoma_LUAD_TCGA-78-7535-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
LD-69-ZV56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.39221
stratum oriens of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13221
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OS-01A-12R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HI-7169-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
NAPG	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-1293	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
BRD-K47170544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45817
VZ in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08779
STXBP2	Pathway Commons Protein-Protein Interactions	1.0	null
FAM21A	Pathway Commons Protein-Protein Interactions	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.980832
benserazide-641	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K05804044_AZ-628_A375_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ANXA7	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K16541732_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889154
Sarcoma_SARC_TCGA-DX-A3UB-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHF8-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.61712
BRD-K96619480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14951
GTEX-OXRN-1326-SM-3LK5V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.944025
GSE57871_8_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00882
LMO7	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K60067222_-666_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.859804
BRD-K47049026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97866
GTEX-R55C-0008-SM-48FCF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09849
PPP6R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15444
hsa-miR-760	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
BRD-K68174511_torin-2_PC3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE87615_1_v_3_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K15300571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18378
GTEX-QDVJ-0626-SM-48U1T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34898
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.834228
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12864_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USP36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96478
VZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.65273
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE231648_4_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BCL3	ChEA Transcription Factor Targets	1.0	null
NB-12-ZK38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.709897
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BC-74-QN56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.399024
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAB10	Pathway Commons Protein-Protein Interactions	1.0	null
WC-16-IR43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.36517
CRCGN015_MCF10A.WT.HP_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.38234
CFL1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE179880_10_v_13_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JX-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ccr5interacting	GeneRIF Biological Term Annotations	1.0	null
BRD-K92241728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32615
BRD-K89300187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0352
inferolateral temporal cortex (area TEv, area 20)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.29844
GTEX-XUJ4-0008-SM-4BOQI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83054
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28366
IZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.48779
CRCGN016_MCF10A.WT.HP_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.57323
Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.9051
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MS-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.33304
CRCGN016_MCF10A.TP53.M_24H:G07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.40297
BRD-K75036062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22204
BRD-K42436189_AZ20_A375_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN016_MCF10A.TP53.M_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.37564
GSE220058,GSE220059_0_v_1_prrc2b_human	RummaGEO Gene Perturbation Signatures	1.0	null
WC-09-GD62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.432227
CRCGN017_MCF10A.WT.HP_24H:E14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6367
PLEKHA5	Pathway Commons Protein-Protein Interactions	1.0	null
BA-40-IU73_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.286214
EB-66-IH06_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.250577
GTEX-R45C-0926-SM-3GAD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11754
BRD-K47349225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16911
GSE198165,GSE198166_9_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ED-05-LQ40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.421931
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-A19500257_geldanamycin_MCF10A_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.31479
endopiriform nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18604
osteosarcoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.344449
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE174701_1_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU119	CCLE Cell Line Gene CNV Profiles	1.0	1.35659
BRD-K56001384_A8674_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A75409952_wortmannin_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K36me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tanespimycin-4430	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
mantle zone of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74901
PMC12178829-mmc4.xlsx-Sheet_4-MEG3-KD_Up-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K69840642_HDAC6 inhibitor ISOX_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SCC-13 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.753
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02401
GSE193258,GSE193259_9_v_15_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RSU1	Pathway Commons Protein-Protein Interactions	1.0	null
NFE2	ENCODE Transcription Factor Targets	1.0	null
BRD-K12502280_TG-101348_MCF10A_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE119978,GSE180930_3_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SHB	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN010_HEPG2_24H:D02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1981
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10274
BRD-K19011391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21792
GTEX-S4Z8-0926-SM-4AD6Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965977
BRD-K45712538	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39556
BRD-K75081836_-666_ASC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.037
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09185
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3Y7-01A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AC-36-SY22_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.781249
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H2-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
AC-30-XU83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.549812
AURKB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00858358
GSE210101,GSE210114_0_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
ParietalLobe	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.00794
GSE86507,GSE86509_7_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PHA-00745360-3827	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE169205_3_v_1_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
PBX3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
oxprenolol-6145	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K00667983	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10582
CRCGN016_MCF10A.WT.HP_24H:O14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10176
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-3026-SM-3NMA2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61457
LF-50-IZ49_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.202322
CCR5	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN016_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.2209
Perturb_11623_KD_DUSP11_SRP113334	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.37306
GTEX-R55E-0008-SM-48FCG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44181
BRD-K28006645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40485
KIF2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18732
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.231102
GSE122101,GSE122103_3_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TIMM17B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28276
GSE151612_0_v_11_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Tcf1_KO_GDS1473_307_mouse_Pancreatic islets	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K12502280_TG-101348_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K57200567	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05893
BRD-K38935430	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57913
CRCGN015_MCF10A.TP53.M_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.61925
EW8	CCLE Cell Line Gene CNV Profiles	1.0	1.51285
GSE151612_0_v_7_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Uterus-fibroblast	Tabula Sapiens Gene-Cell Associations	1.0	10.8468
7734_SEC13_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.31331
UBR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11082
Penis_Foreskin_Fibroblast_Primary_Cells_skin01	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.855625
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K86899078_-666_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AE-64-KN26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.543001
CACYBP	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K17743125_belinostat_HA1E_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CDK5	Pathway Commons Protein-Protein Interactions	1.0	null
GSE135350_3_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T6MO-1526-SM-4DM57	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942682
FA-43-TP28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.238273
ME-31-RM40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.734634
AB-84-PK04_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.286233
SCH	GDSC Cell Line Gene Expression Profiles	-1.0	-1.71748
BRD-K85818861_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K56799639	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00784
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.844309
FOXP2_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K49865102_PD-0325901_A375_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
presents	GeneRIF Biological Term Annotations	1.0	null
GSE152432_1_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE238116_3_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052192
ATP5MC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78938
PMC11426526-ppat.1012555.s011.xlsx-DEG_MDDC_Jurkat_LPS_vs_MDDC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R3RS-1326-SM-48FE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.8292
VE-46-XV53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.20046
outer CP in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04998
EEF2K	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00487083
VZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.988755
ANXA3	Pathway Commons Protein-Protein Interactions	1.0	null
Corpus callosum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.894
BRD-K92632379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.68316
BRD-K56729241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14773
KIF5B	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K06863452	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.72257
EN	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.84716
GSE217452_2_v_1_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K83125173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25142
HC-18-NB46_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.237219
bicuculline-2139	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-V955-0726-SM-3GAFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.87014
uterus	GTEx Tissue Gene Expression Profiles	1.0	0.992589
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.499
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.383
Sarcoma_SARC_TCGA-DX-A7ER-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
peripheral nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.01259
Inferior salivatory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14879
BRD-K03063480_PF-477736_MCF10A_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FOXP3	ChEA Transcription Factor Targets	1.0	null
bone cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.334498
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPIC-0726-SM-3GADW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26506
ChIP_TCFCP2L1_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K84388444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2364
BRD-K53414658_-666_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Amelanotic melanoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.095
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
organic acid transport	GO Biological Process Annotations 2015	1.0	null
BRD-K60476892_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NHP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00073
CRCGN010_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8102
BB-20-UU03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.853054
GTEX-TSE9-3126-SM-4DXSY	GTEx Tissue Sample Gene Expression Profiles	1.0	2.59886
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SIRT6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00814
CRCGN017_MCF10A.WT.HP_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.53875
BATF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26733
BB-09-GD09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.256977
GM12878	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-2.331
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-05A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Motor nucleus of trigeminal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4088
BRD-K83845379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79139
GSE125007,GSE125008_6_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CD-35-BD44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.636577
HT-3	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.95825
EA-33-QC97_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.213691
gigantocellular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11651
GSE172295_1_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RD-90-OY66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.4048
HT29	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.8634
SCFD2	Pathway Commons Protein-Protein Interactions	1.0	null
NR0B1	ChEA Transcription Factor Targets	1.0	null
DC-31-WP64_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.255241
CRCGN016_MCF10A.WT.HP_24H:O13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.50233
GTEX-XLM4-0011-R10A-SM-4AT5P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835942
BRD-K28467592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03407
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ANKRD27	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00393984
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.875192
QE-18-WG07_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.402044
UF-14-LK87_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.342497
BRD-K67572910	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65393
PMC12749419-41598_2025_28826_MOESM3_ESM.xlsx-RFT_iBody3_hexaplicate-Genes_MBD1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K85708426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03267
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_id_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K21025364_NVP-TAE226_A375_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SHPRH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25515
BRD-K79090631_CGP-60474_HCC515_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AF-41-QY60_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.477306
GSE108326_1_v_0_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CB-01-MR53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.204091
DB-40-HA40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.479232
dicarboxylic acid transport	GO Biological Process Annotations 2015	1.0	null
Epididymis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.306
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28366
RAPGEF4	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RWS6-0326-SM-2XCAP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.905394
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.10387
Presubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46043
NB-24-VE53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.374582
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09243
CRCGN008_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0165
SDF4	Pathway Commons Protein-Protein Interactions	1.0	null
Sarcoma_SARC_TCGA-DX-A8BK-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6604319-13072_2019_278_MOESM3_ESM.xlsx-CEM_ect_TET2_DEGs_DMRs_hDMRs-Unnamed_4_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
diprophylline-1853	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SIN3A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GNB2L1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K23589316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61783
AD-51-SS86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.62506
IE-80-DC24_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.496647
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HS 895.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.36255
endometrium_4a	HPA Tissue Sample Gene Expression Profiles	1.0	0.879718
GTEX-QXCU-0226-SM-2TC5W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33168
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4QR-0726-SM-2I5GO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.990252
OVCAR5	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.49566
BRD-K83183132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12965
GSE215086_8_v_6_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZC3H13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78506
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_y_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A75409952_wortmannin_T3M10_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.30321
TAGLN2	Pathway Commons Protein-Protein Interactions	1.0	null
ARF4	Pathway Commons Protein-Protein Interactions	1.0	null
GSE178227_1_v_2_tet1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NIPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07947
EPS8L2	Pathway Commons Protein-Protein Interactions	1.0	null
AOB, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20794
AC-55-XA97_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.241844
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K41700289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05207
intracellular part	GO Cellular Component Annotations 2015	1.0	null
KAT2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K05151076_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K39256324_Rottlerin_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RERFLCSQ1	DepMap CRISPR Gene Dependency	1.0	2.25575
relapsing-remitting multiple sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.075
BACH1	ENCODE Transcription Factor Targets	1.0	null
GSE178255_1_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K83972459_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
SARS-CoV_0Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.59776
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61I-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08629
ZNF135	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.4599
SIRT7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00281469
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.41223
BRD-A18411371_2-[(chloroacetyl)(3-chlorophenyl)amino]-N-cyclohexyl-2-(4-methoxyphenyl)acetamide_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ABL1_knockdown_144_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.04374
HT-1197	GDSC Cell Line Gene Expression Profiles	-1.0	-1.60131
GTEX-R55E-0526-SM-2TC6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04118
ventrolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20792
BRD-K05104363_PD-184352_A375_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A25736793_everolimus_HCC515_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.336954
ATF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VAMP7	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-4271	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
FA-63-WI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.26939
BRD-K13094524_PFI-1_HCC515_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K62351887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13626
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K39546571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24571
single-organism localization	GO Biological Process Annotations 2015	1.0	null
Sarcoma_SARC_TCGA-FX-A48G-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A59F-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFON-1726-SM-4LVMQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3748
CRCGN009_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12726
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.4717
amygdaloid complex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.2556
alfaxalone-3135	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZFPL1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SW1116	GDSC Cell Line Gene Expression Profiles	-1.0	-1.73485
GSE144115_1_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EDF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04653
OVSAHO	CCLE Cell Line Gene Expression Profiles	1.0	1.90088
GSE130396_1_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE151612_4_v_11_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Primary somatosensory area, lower limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57553
H3K9me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
COPG1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K35646839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08903
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K93123848_RAF 265_A375_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BE-25-UR78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.587376
torasemide-5476	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WYVS-2326-SM-3NMAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40992
BE-82-TS38_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.314226
EB-67-WB79_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.227768
PMC12356310-mmc1.xlsx-Rep_3_Control_and_MTR4_KD-Gene_Name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE94849_6_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NUDC	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.91335
TBP_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE241036_4_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158458_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RABL3	Pathway Commons Protein-Protein Interactions	1.0	null
FF-86-NH56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.773277
GB-57-XV52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.648807
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K19969409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2597
inferolateral temporal cortex (area TEv, area 20)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.901016
BRD-K42918627_GSK-2126458_A549_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DU4475	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58797
H3K9me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A45498368_WYE-125132_A549_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-OOBJ-1626-SM-2I3F7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826508
small_intestine	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.12478
GTEX-WFG8-0001-SM-4LVN8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940183
SMC3	Pathway Commons Protein-Protein Interactions	1.0	null
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30746
WM793_SKIN	CCLE Cell Line Proteomics	1.0	3.44075
BRD-K99827210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88298
L-glutamate transmembrane transport	GO Biological Process Annotations 2023	1.0	null
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
QD-57-GT11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.320608
GTEX-WL46-0011-R1A-SM-3LK6M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856488
trazodone-7410	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN010_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.65526
induseum griseum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01211
BRD-K87387614_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K69536411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31345
CRCGN010_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.19845
PITPNB	Pathway Commons Protein-Protein Interactions	1.0	null
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.62339
intermediate part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74081
Ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE164874_5_v_12_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
cerebellar cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.375743
GSE201239_6_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K71893034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63381
GTEX-OIZI-0626-SM-2XCEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.97058
HCC202	DepMap CRISPR Gene Dependency	1.0	2.05593
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NA-16-OJ70_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.490803
DANG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42195
BA-56-QV45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.553146
NRF1	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E0-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K00773626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16277
NET1_KD_GDS4196_436_human_AGS - gastric adenocarcinoma cells - (63 shRNA Knock-Down)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
intermediate stratum of r3Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03472
BRD-K90571714	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51356
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.76077
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A1H6-01B-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
elevated	GeneRIF Biological Term Annotations	1.0	null
paracetamol-3025	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.926857
CRCGN015_MCF10A.WT.HP_24H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.40076
TF-77-DW08_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.294025
organic substance transport	GO Biological Process Annotations 2015	1.0	null
GTEX-X4EP-0526-SM-3P5YW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15451
EB-09-LQ45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.257913
HCFC1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.225
RPS6KA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25112
NCIN87_STOMACH	CCLE Cell Line Proteomics	1.0	2.72655
BRD-K77713205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13943
RAB3GAP1	Pathway Commons Protein-Protein Interactions	1.0	null
RHOA	Pathway Commons Protein-Protein Interactions	1.0	null
GSE146982_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PA-70-ZC89_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.27462
orbital frontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01129
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AD-43-XJ59_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.245149
GTEX-OXRK-0008-SM-3NB28	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27172
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.832531
BRD-K49865102_PD-0325901_MCF10A_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K81418486_vorinostat_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CALR	Pathway Commons Protein-Protein Interactions	1.0	null
ERGIC3	Pathway Commons Protein-Protein Interactions	1.0	null
retrosplenial cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1529
GTEX-R55G-0426-SM-48FDH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988518
sisomicin-2853	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054063
mantle zone of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21049
Lateral reticular nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20432
BD-69-XG81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.378642
vorinostat_homo sapiens_gpl570_gse34880	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K20061970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07343
phenformin-2350	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NUDUL1	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4688-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K86797399_pracinostat_HT29_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MZ7-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CDK4	Pathway Commons Protein-Protein Interactions	1.0	null
Peripheral nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.459
HEC151	CCLE Cell Line Gene Expression Profiles	-1.0	-1.53888
LB831-BLC	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.24735
PD-70-VS77_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.17154
BRD-K58836556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93856
mantle zone of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07648
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.972373
GSE158431_5_v_7_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K03855997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99923
posteroventral (inferior) parietal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.85214
CRCGN011_HEPG2_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.433
DA-27-BW40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.953576
GTEX-S32W-0526-SM-4AD6F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996614
KLC2	Pathway Commons Protein-Protein Interactions	1.0	null
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAB19	Pathway Commons Protein-Protein Interactions	1.0	null
Ceritinib	DeepCoverMOA Drug Mechanisms of Action	1.0	0.66
LB771HNC	DepMap CRISPR Gene Dependency	1.0	5.59689
JHH-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.997992
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67V-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K59434830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.51603
GOPC	Pathway Commons Protein-Protein Interactions	1.0	null
ECC10	CCLE Cell Line Gene Expression Profiles	-1.0	-1.71566
r7 part of parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.96306
GSE210580_0_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PHB	Pathway Commons Protein-Protein Interactions	1.0	null
GE-29-ZM45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.331479
GSE57397,GSE57399_1_v_0_fbxw7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4283	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
VZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15388
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5185-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BC-74-QN56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.262045
BRD-K93747373_HG-5-113-01_MCF10A_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC4944136-srep28995-s2.xls-OTX2-gene_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
GABPA_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.069526
CTCF_fibroblast of mammary gland_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DF-84-RT50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.477016
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.6274
CRCGN009_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.47978
GTEX-SE5C-0326-SM-4BRWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.9951
BRD-K59938516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31042
HDAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12058
GSE220806_1_v_3_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WZTO-2926-SM-3NM9I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845701
CJUN-26792858-CHIP-SEQ-BT549-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TP73	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8602
FB-39-CW59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.46288
KAT2A	ENCODE Transcription Factor Targets	1.0	null
BRD-K66287173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42026
mediodorsal nucleus of thalamus_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.37752
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
IE-80-DC24_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.371912
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4841-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9174260-41467_2022_30960_MOESM6_ESM.xlsx-S4-RAS1_unique_GATA2-CELSR2_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
wortmannin-1184	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE239844_11_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.3484
H3K36me3_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2841
CCND1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00812772
AD-16-HL96_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.778024
ELF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COPI vesicle coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.122
PC-80-LV29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.318369
GSE113005_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K75584297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21174
DE-20-VX20_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.263351
PLS1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE190186,GSE190188_0_v_10_apoe_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2857-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K63008302	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0505
SMAD4	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN014_HEPG2_24H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.3545
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AA-58-FJ71_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.211419
POLR2A_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K39087168	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58164
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPECC1L	Pathway Commons Protein-Protein Interactions	1.0	null
GSE88819_5_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XPVG-0326-SM-4B653	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.041
GTEX-UJHI-1726-SM-3DB9B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14824
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE226091,GSE226092_3_v_1_sall1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
Gamma-hydroxybutyric acidaemia_CNS - Brain - Hippocampus (MMHCC)_GSE2866	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.31395
EZH2	ENCODE Transcription Factor Targets	1.0	null
CTCF_A549_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHSA0108	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.82252
LB-04-KP05_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.323939
PC-87-OG75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.402184
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
BRD-U64521890_XMD16-144_MCF7_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE184892_6_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
non-neuronal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.612958
BRD-K43714461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43482
intermediate stratum of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49311
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.11567
rab9	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.033
HUP-T3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.29205
CANX	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN014_HEPG2_3H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.5198
PC-80-LV29_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.237903
Lung adenocarcinoma_LUAD_TCGA-50-8460-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE58724_1_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A19037878_trichostatin A_PHH_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K58596567	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02427
OAW42	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.877578
Anteroventral periventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16498
VIPAS39	Pathway Commons Protein-Protein Interactions	1.0	null
FF-86-NH56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.709126
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
lateral part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50688
AM-095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4439
CF-97-KZ12_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.549587
BRD-K29415052_NVP-BGT226_HCC515_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.867486
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CLDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29125
SEPTIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44515
GTEX-U4B1-0726-SM-4DXUA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853081
hsa-miR-631	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
PF-01378883-00-6410	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
leukocyte	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K84478344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2503
SCAMP3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE112860_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A-CA-04-2009(H1N1)_24Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.04085
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NE-37-JX51_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.370059
CRCGN013_HEPG2_24H:O14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19015
Lung adenocarcinoma_LUAD_TCGA-44-A47B-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CA-96-UO48_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.295378
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.60973
CRCGN015_MCF10A.TP53.M_24H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.16092
Cortical amygdalar area, posterior part, medial zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56435
PMC11221067-JCMM-28-e18520-s002.xlsx-Supplementary_Table_2-CEBPD_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IF-03-OL58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.418023
MCF7_Abexinostat_1µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00924106
GSE202434,GSE202438_7_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BE-24-LQ28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.325024
PMC7857731-elife-63093-supp1.xlsx-DEG_MITF-X6vsEV-SkMEL28-Unnamed_1_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K54606188_(+)-JQ1_HCC515_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CW-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.07129
p2 portion of the substantia nigra pars compacta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41554
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PF-00562151-00-5922	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K17743125_belinostat_MCF7_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WHSE-0011-R5A-SM-3P5ZO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966797
BA-60-DR11_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.277087
Brain - Hippocampus	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.32536
ELF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5565
GSE154767_4_v_3_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE118548_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BF-10-IO69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.246608
BRD-K53932786_2-Dichloromethyl-4-ethylsulfanyl-6-phenyl-[1,3,5]triazine MLS-0208612.0001_PC3_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CD-26-MB82_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.228906
BRD-K13087974_D3943_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K16485616_mocetinostat_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-33-4533-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ABR	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-S32W-2126-SM-2XCB1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16539
GSE178255_2_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
signal	GeneRIF Biological Term Annotations	1.0	null
BRD-K68547601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97374
Right nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.617
BRD-K53903639_480743.cdx_HCT116_6.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SW-1573/S1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.651
CRCGN014_HEPG2_24H:J13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.618
ACAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65095
BRD-K12531686	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99211
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
sirolimus-1162	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-S4Q7-0003-SM-3NM8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5949
GSE214685_0_v_1_nsun2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VAMP3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K37892442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57326
GA-09-TM90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.260983
DHX30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76991
BRD-K30269093	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24501
RAN	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN012_HEPG2_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2322
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A5A6-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH2227	CCLE Cell Line Gene Expression Profiles	1.0	1.49281
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.87449
ID-96-UX79_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.250186
integral component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.146241
SUM225CWN	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.29024
BRD-K16478699_PLX-4720_A375_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RF-95-QO64_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.23859
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.48884
GTEX-PX3G-0826-SM-48TZS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39504
CA-90-RU33_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.270941
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.8913
DD-47-GB64_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.22716
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.266203
AC-93-LT43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.252156
DA-17-YW85_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.272922
H3K79me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NANOG	ChEA Transcription Factor Targets	1.0	null
G118	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.17648
SIRT6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
l-amino acid transport	GO Biological Process Annotations 2015	1.0	null
USF1_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YA-78-MS95_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.691792
CPNE3	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4642-01B-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K19770687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.14246
GSE185944_0_v_3_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K36me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AF-00-QK19_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.475717
CRCGN016_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.78561
DMS-114	GDSC Cell Line Gene Expression Profiles	1.0	2.17739
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WEY5-0726-SM-4LMID	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858464
KB-78-BE93_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.201977
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.880849
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCL3	ENCODE Transcription Factor Targets	1.0	null
ARAP1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
metformin-1858	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.22097
DA-07-LL18_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.31381
DD-71-LY65_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.39097
CEBPB	JASPAR Predicted Transcription Factor Targets	1.0	null
GNAI1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K14191038_JFD02227_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1488
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4PQ-2626-SM-33HC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827951
KF-18-RY71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.239293
BC-26-LE04_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.281288
GOLPH3	Pathway Commons Protein-Protein Interactions	1.0	null
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.23662
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0855
BRD-K69840642_HDAC6 inhibitor ISOX_PL21_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SMAD2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-U07805514_saracatinib_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.3373
BRD-A75409952_wortmannin_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.94429
RVX-208	DeepCoverMOA Drug Mechanisms of Action	1.0	0.4
dactinomycin_mus musculus_gpl1261_wild type_gds2456	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SEC23A	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-TML8-0526-SM-32QOQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02999
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1609
GSE160373_5_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169152_3_v_6_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BCL3-23251550-MUSCLE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
IL2_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
RA-86-LI22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.226914
BRD-K67602895	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51483
COV362	CCLE Cell Line Gene CNV Profiles	1.0	1.45316
superficial stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.3781
ChIP_KLF4_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
AB-12-PP61_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.675941
JiyoyeP-2003	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.37226
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70N-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DD-01-VE87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.537272
BRD-K69840642_HDAC6 inhibitor ISOX_SKM1_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
UF-98-OM26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.203645
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43193
BRD-K70401845_erlotinib_MCF10A_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE234289_3_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
CD-59-MG26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.264764
GTEX-QLQW-1326-SM-2S1QS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.19036
BRD-K40016301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29236
BRD-K34519170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5583
H3K36me3_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K83238251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69712
CRCGN015_MCF10A.WT.HP_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.59489
ACKR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.004492
BRD-K45978015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93662
BRD-K36644177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29989
HA-22-CY42_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.681604
BRD-K72703948_ZM-447439_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K56013842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06887
BRD-K26664453_-666_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
inner SZ in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.42315
CMK	CCLE Cell Line Gene CNV Profiles	1.0	1.42298
b-lymphocyte cell line	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K19800225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26769
Olig2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.8185
496100420_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.42744
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
pituitary	GTEx Tissue Gene Expression Profiles	1.0	1.44172
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.326
rostral ventrolateral reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5703
GTEX-X62O-2226-SM-46MW3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26515
GTEX-QCQG-1926-SM-2S1PI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05933
PC-62-AQ92_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.606578
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.57026
BCLAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZH-0326-SM-3DB7A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06932
ACAP2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SK23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21845
BRD-K18294143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06023
PMC12179525-mmc1.xlsx-Group_HNF4A_vs_Null_sign-Supplemental_Table_S1_Differentially_expressed_genes_in_HNF4A-transduced_cells_vs_Null_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
metastasis	GeneRIF Biological Term Annotations	1.0	null
FE-37-OL13_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.416713
Polkadots	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.879
PMC7857731-elife-63093-supp1.xlsx-DEG_MITF-X6vsEV-SkMEL28-Unnamed_2_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SARS-CoV_84Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.73297
JUND	ENCODE Transcription Factor Targets	1.0	null
AB-09-YX02_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.200323
BRD-K45271289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34698
acidic amino acid transport	GO Biological Process Annotations 2015	1.0	null
SCHNEIDER-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.916
GCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13035
GSE207135_2_v_0_sod2_human	RummaGEO Gene Perturbation Signatures	1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CE-23-HP88_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.217014
BRD-K81418486_vorinostat_A549_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
sk-n-sh cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.778155
MFM-223	COSMIC Cell Line Gene CNV Profiles	1.0	2.15687
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tetrandrine-2520	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE122101,GSE122103_3_v_4_ssu72_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FF-28-ES17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.761402
GTEX-N7MS-2625-SM-3LK77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.681
WB-82-EL69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.463
QC-49-CA55_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.239271
Acute Myeloid Leukemia_LAML_TCGA-AB-2910-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K43603649	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12609
CTCF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IDRA-21	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17848
BRD-A82371568_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K25177502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.97824
BRD-K17259076	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33354
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09886
BRD-K41895714_AS605240_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7211-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GAA	Pathway Commons Protein-Protein Interactions	1.0	null
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.931992
BC-72-DZ30_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.311505
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31719
COPB2	Pathway Commons Protein-Protein Interactions	1.0	null
PDE4D	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00812052
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
Esophageal adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.864
COPB1	Pathway Commons Protein-Protein Interactions	1.0	null
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
STAT3	ENCODE Transcription Factor Targets	1.0	null
NCIH1355	CCLE Cell Line Gene CNV Profiles	1.0	1.34539
BRD-K93484038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17737
FOXP2	ENCODE Transcription Factor Targets	1.0	null
MXI1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
J-82 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.521
ELF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLF4	ChEA Transcription Factor Targets	1.0	null
procyclidine-4233	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1395	DepMap CRISPR Gene Dependency	1.0	2.42886
LGMN	Pathway Commons Protein-Protein Interactions	1.0	null
Mesothelioma_MESO_TCGA-MQ-A6BR-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K17743125_belinostat_HA1E_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BAZ1A	Pathway Commons Protein-Protein Interactions	1.0	null
motor nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.59494
BRD-K78747341	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25354
POLR2AphosphoS5_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7058-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ME-31-RM40_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.233644
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BD-69-GX17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.302513
Paragigantocellular reticular nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.94935
BRD-K35943892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04749
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.867483
GTEX-P4PP-0326-SM-33HC4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.65612
LOU-NH91	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.18882
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BB-62-SZ35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.14336
DA-10-HD17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.510902
UA-39-TN76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.38174
GB-11-TA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.210327
large intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.272997
HD-99-BT62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.696626
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE165122_2_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OIZG-0726-SM-33HBL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02248
GTEX-U4B1-0826-SM-4DXTW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.922631
GTEX-SIU7-0001-SM-3NMAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.897295
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.5691
STARD10	Pathway Commons Protein-Protein Interactions	1.0	null
HCFC1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K81418486_vorinostat_SKM1_6.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ESS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20327
HMGN3	ENCODE Transcription Factor Targets	1.0	null
JVM-3	GDSC Cell Line Gene Expression Profiles	-1.0	-2.03365
prednisolone_homo sapiens_gpl570_gse32962	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cefalexin-5250	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MNX1-26342078-MIN6-4N-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SYK	Pathway Commons Protein-Protein Interactions	1.0	null
CTNND1	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HI-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K36me3_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.35254
GTEX-R55E-0011-R9A-SM-2TC6C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54451
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BF-69-DN58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.299581
GSE210150_0_v_1_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ID-00-IC14_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.252201
GSE233647_4_v_6_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
TMEM132A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32102
Granulosa cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
RAB5C	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-A45498368_WYE-125132_PC3_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
VIIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.866073
UACC812	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.800796
BRD-K42918627_GSK-2126458_A549_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AA-46-GL76_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.04999
BE-38-UW72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.458987
EGR1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21226
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K13094524_PFI-1_HCC515_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K36me3_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:H04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19093
ketoprofen-4286	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE112860_3_v_2_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN012_HEPG2_24H:B07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.12549
CRCGN017_MCF10A.WT.HP_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.5522
fenbufen-2308	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K31577322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.63803
BRD-K91917132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31341
YY1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KAT2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ADAM10	Pathway Commons Protein-Protein Interactions	1.0	null
TCF7L2_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cetuximab_homo sapiens_gpl570_gse21483	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ELK4	ENCODE Transcription Factor Targets	1.0	null
NOP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43024
IM-95	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.43176
BRD-K53544328	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10694
BRD-K33689641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39464
Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23236
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.83857
DF-03-OP38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.275694
BRD-K19590405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69482
GSE120413,GSE120447_0_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K76114616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00972
parabigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.47794
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CF-24-KQ98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.635331
BRD-K89423851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26406
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K79259477_KIN001-265_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE226249_5_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAP2K4	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K59317601_INK-128_A549_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K49328571_dasatinib_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
496100622_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.286
BRD-A13122391_16-HYDROXYTRIPTOLIDE_PC3_24.0_h_0.08_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K99252563_QL-XII-47_MCF10A_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K58194737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86958
BRD-K44227013_ponatinib_A375_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
spanning component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.447656
AC-30-XU83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.302669
NC-52-AG88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.33623
BRD-K07979116	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77006
GA-04-JM33_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.309835
GTEX-PLZ4-1626-SM-3P618	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.862851
AC-71-YF45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.441934
BRD-A19037878_trichostatin A_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AF-83-BX08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.34442
head of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.874237
mediodorsal nucleus of thalamus_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.40504
GTEX-O5YV-0626-SM-3LK64	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30905
GSK3B_knockdown_158_GSE35351	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.76189
CA-90-RU33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.422317
BRD-K40674409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23406
BRD-K09499853_KU 0060648 trihydrochloride_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AD-42-US78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.278653
CRCGN016_MCF10A.TP53.M_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.8799
gliomas	GeneRIF Biological Term Annotations	1.0	null
BRD-K04546108_JAK3 Inhibitor VI_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K93123848_RAF 265_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE158815_1_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169205_3_v_6_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
YY1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K34761198	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53296
CRCGN013_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17618
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02165
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.70987
BRD-K75451592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8705
BRD-K91459693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2321
CRCGN016_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.46407
AE-39-DG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.235399
GTEX-PX3G-2026-SM-48U1H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17106
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R7-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CB-11-GB40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.211533
DA-10-HD17_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.862134
BRD-K66762690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.29194
GPATCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62383
EXOC4	Pathway Commons Protein-Protein Interactions	1.0	null
TCFCP2L1-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN011_HEPG2_24H:I24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6369
VAPA	Pathway Commons Protein-Protein Interactions	1.0	null
GATA2_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE198165,GSE198166_5_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K05153001_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K36me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BC-62-RZ55_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.6606
WF-85-JN16_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.275431
BRD-K01436366_XMD-1150_MCF7_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.91399
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A3MF-01A-12R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCL6-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
layer 5 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13346
CTV1DM	DepMap CRISPR Gene Dependency	1.0	3.35542
CRCGN017_MCF10A.TP53.M_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.8589
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01873
Telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
UHRF1	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K19645475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57938
BRD-A68930007_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CB-06-FE89_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.40408
UACC893	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.08261
TRAPPC4	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K59006776	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25901
NDNL2	Pathway Commons Protein-Protein Interactions	1.0	null
FOSL2	ENCODE Transcription Factor Targets	1.0	null
BRD-K88119862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36101
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neuroendocrine cell_Trachea_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
prasterone-3097	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-QH-A6CX-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EIF4A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1929
GTEX-Q2AG-0011-R10A-SM-2HMLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53084
SNX14	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K89744662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33712
CRCGN009_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.66962
CRCGN017_MCF10A.TP53.M_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.37004
HCC38	CCLE Cell Line Gene CNV Profiles	-1.0	-2.20312
BRD-K79090631_CGP-60474_MCF7_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CHMP1A	Pathway Commons Protein-Protein Interactions	1.0	null
TJP2	Pathway Commons Protein-Protein Interactions	1.0	null
SIGMAR1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K54262203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04488
ETS1-20019798-JURKAT-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
layer 1 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19473
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.865719
YA-85-VH07_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.300664
BRD-A18328003_GDC-0980_MCF10A_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Entorhinal area, medial part, ventral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.07618
GSE146982_3_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
b12	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.464
Sarcoma_SARC_TCGA-DX-A3UF-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AD-30-OK99_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.286819
SNUC1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.03731
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AF-40-QU33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.265453
STAT1	Pathway Commons Protein-Protein Interactions	1.0	null
ATP6V1E1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K27782186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12208
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4352-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BD-25-SA37_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.382859
H3K79me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EPS8L3	Pathway Commons Protein-Protein Interactions	1.0	null
tyloxapol-3074	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC1162	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30099
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE138468_3_v_6_dyrk1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K50291875	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48498
PMC9038526-mmc1.xlsx-postCOVID_ctr_vs_LPS-symbols_98_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RN64-1026-SM-48FDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59953
Lung adenocarcinoma_LUAD_TCGA-78-7163-01A-12R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AC-84-QG99_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203526
CRCGN016_MCF10A.TP53.M_24H:M01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6253
GAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12786
BRD-K58242935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40943
GA-04-JM33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.10358
AE-00-WU78_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.240367
UB-62-DF90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.227594
GSE129241_4_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
AA-11-RO46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.518129
BRD-K42436189_AZ20_A549_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61O-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EFO27	DepMap CRISPR Gene Dependency	1.0	2.0119
Uterus	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.69271
docetaxel_homo sapiens_gpl570_gse33455	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCIH2126_LUNG	CCLE Cell Line Proteomics	1.0	3.00357
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51K-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YA-34-DT48_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.221277
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPP2CA	Pathway Commons Protein-Protein Interactions	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2941-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GD-07-HO70_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.489914
BRD-K92749855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9585
POLR3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25646
Lung adenocarcinoma_LUAD_TCGA-73-4659-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.27651
Cardiac Hypertrophy_Myocardial tissue_GSE5500	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.99368
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KIFC1	Pathway Commons Protein-Protein Interactions	1.0	null
KB-17-PN92_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.238993
BRD-K81418486_vorinostat_PL21_6.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K93725829_ERK inhibitor 11e_A375_24.0_h_0.5_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EA-92-CV45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.288554
AF-99-HA02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.499982
lateral part of r8B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5666
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A767-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K26694226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06453
ED-00-OH22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.333549
PIK3R1	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4761-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
P300-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-WFON-2026-SM-4LVMW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32732
HLA-C	Pathway Commons Protein-Protein Interactions	1.0	null
17410534-Table1	GeneSigDB Published Gene Signatures	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-NPJ7-0008-SM-4E3JS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03418
SW756	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.0087
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6489
rnf2_20805357_megakaryocytic_l8057_lof_mouse_gpl1261_gse33659	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.774626
BRD-K94012289_OSI-027_MCF10A_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC7933708-mmc2.xlsx-DNMT-target_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
CC-20-FN31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.277587
chlorzoxazone-2263	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CDC42	Pathway Commons Protein-Protein Interactions	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23727
abducens nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04195
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.866343
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K23481525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93765
AC-95-NR38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.399566
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
superficial stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15193
GSE185944_5_v_3_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KC-32-GO33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.350955
BRD-A17658676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15101
GSE101537_1_v_3_neurog3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HS834T	CCLE Cell Line Gene Expression Profiles	1.0	1.44985
BRD-A39996500_radicicol_MCF10A_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE185944_5_v_4_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LD-69-ZV56_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.226604
intrinsic component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.116192
AC-49-NG46_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.200666
ADRM1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-R55G-1626-SM-48FF4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8214
GSE112860_5_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
XD-68-MP63_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.217275
Perturb_4789_KD_Firre_ERP009127	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.80768
H3K36me3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OPM2	DepMap CRISPR Gene Dependency	1.0	2.00598
specific	GeneRIF Biological Term Annotations	1.0	null
BRD-K86492010_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MAPK7	Pathway Commons Protein-Protein Interactions	1.0	null
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.02084
GB-11-TA37_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.590679
GTEX-QDVJ-1126-SM-48U1U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23256
H3K27ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE142210_2_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A26640795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.138
transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.611625
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
NC-54-XY91_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.316295
MAX_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:E16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.60009
BRD-K40630587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.7739
BRD-K13299646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35552
SARS-ddORF6_84Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.12297
single-organism process	GO Biological Process Annotations 2015	1.0	null
PTK2	Pathway Commons Protein-Protein Interactions	1.0	null
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAB2A	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K05104363_PD-184352_A375_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.96981
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9795333-mmc4.xlsx-HUES66_Ex_SATB2_c1_c4_c9-X-linked_genes_SATB2	Rummagene Transcription Factor Associations 2026	1.0	null
Fetal Heart	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.02997
USF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YV-2026-SM-2D7VS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06227
BRD-K90526956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86553
GTEX-VUSG-0126-SM-4KL1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38907
BRD-K62288678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56945
CRCGN016_MCF10A.TP53.M_24H:E20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.26666
Accessory olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12518
TFAP2C	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K08458391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54778
BRD-K78647367	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.30893
GSE113329,GSE113335_3_v_4_taf6l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UF-06-JB00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.488055
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
postsynapse	SynGO Synaptic Gene Annotations	1.0	null
DUSP3	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN017_MCF10A.WT.HP_24H:F11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05355
harmaline-2149	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN014_HEPG2_24H:H02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.97679
VCAP	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48997
GTEX-Q2AG-1126-SM-48U1P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48752
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6789-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUZC-0008-SM-4BOQG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11097
Ebf2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	45.4902
H3K9ac_Rectal Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.13
VMRCRCZ	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48451
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FE-29-XM40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.692607
GSE157960_2_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XBEC-1526-SM-4AT68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05948
PMC3698521-supp_jem.20120812_JEM_20120812_sm.pdf-26-HOXB6_HOXB6	Rummagene Transcription Factor Associations 2026	1.0	null
VIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.856443
Fatty Liver	CTD Gene-Disease Associations	1.0	1.15831
GTEX-OIZG-0426-SM-3LK5W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28654
GSE196699_4_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
c32	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.145
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.913503
BF-10-IO69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.208958
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE184892_7_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K84203638_4-[(1-methyl-2-oxo-1,2-dihydroquinolin-4-yl)oxy]-N-(4-methylpyridin-2-yl)butanamide_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZNF287	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71693
BRD-K69840642_HDAC6 inhibitor ISOX_SW948_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
bacitracin-3109	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-S4UY-0526-SM-3K2AN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00654
BCAP31	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K77845452	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76845
CRCGN016_MCF10A.WT.HP_24H:E20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.88877
USP9X	Pathway Commons Protein-Protein Interactions	1.0	null
GSE217105_0_v_1_gemcitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K69914820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03427
GSE148252_7_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Paraventricular hypothalamic nucleus, parvicellular division, anterior parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13958
BRD-K80348542_-666_ASC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.92557
BRD-K80895505	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2009
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043265
GTEX-RM2N-1926-SM-48FCU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2508
RAB21	Pathway Commons Protein-Protein Interactions	1.0	null
VDR-23849224-CD4+-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898106
HC-86-IA49_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.465594
PMC10592471-NIHMS1912771-supplement-7.xlsx-D-HEp3-Enh_vs_AA-up_genes-AA_up_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
VZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00671
CRCGN017_MCF10A.WT.HP_24H:H10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15235
CRCGN009_HEPG2_24H:H02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.03388
HCC70	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38401
AA-87-EI21_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.468895
CE-15-YU05_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.482703
BRD-K18822985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22482
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE152441,GSE152442_7_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PPP1R9B	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971959
RA-49-ZB08_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.534692
OF-19-JH77_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.276193
metencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.095563
MAPK14	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K49865102_PD-0325901_A375_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Piriform-amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13655
GSE223241_2_v_0_cdkn2a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
UCHL3	Pathway Commons Protein-Protein Interactions	1.0	null
Transfer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.698
MYC-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
Cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN016_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.87064
TMEM74B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24343
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
BRD-K64890080_BI-2536_BT20_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K67578145_GDC-0879_A375_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN013_HEPG2_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.77121
GSE128730_3_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-330-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GTEX-XBED-0226-SM-47JY8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22444
BRD-K12502280_TG101348_HCC515_24.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-UPIC-0926-SM-4IHLV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.06817
hsa-miR-4739	TargetScan Predicted Conserved microRNA Targets	1.0	0.31417
primary motor cortex (area M1, area 4)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0244
LD-69-ZV56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.834925
GTEX-XBEC-1326-SM-4AT69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28739
TTF2-22483619-HELA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
496100515_HIP_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2867
BRD-K94012289_OSI-027_MCF10A_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HC-01-FD24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.230174
GTEX-NFK9-0626-SM-2HMIV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.993747
PMC8490503-thnov11p9519s3.xlsx-Proteins_Down_MLL-Gene_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN017_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	10.0
PMC4823830-ncomms11171-s4.xlsx-high_in_shRNA_TCF1-GeneSymbol_HNF1A	Rummagene Transcription Factor Associations 2026	1.0	null
QA-27-XW03_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.211962
C-33 A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
IL11RA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52129
PANC1	BioGPS Cell Line Gene Expression Profiles	1.0	0.902991
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72005
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.5062
CADPS2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K73125678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2296
GSE111247_2_v_13_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE48812_4_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TEAD1	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-NFK9-1126-SM-3LK78	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0903
DD-30-SX80_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.299829
DOCK5	Pathway Commons Protein-Protein Interactions	1.0	null
ventral part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63151
light-harvesting complex, peripheral complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.734
GTEX-N7MS-0011-R6a-SM-2HMJ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16533
BRD-K18316646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0787
BRD-K47456612	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41376
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IB-30-KN41_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.296374
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.93057
JF-84-QZ64_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.451344
BRD-K31666794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95658
GSE172020_0_v_2_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.456
CRCGN013_HEPG2_24H:B07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.52638
BRD-K82863660	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.12048
HB-06-WU12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.365747
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-A8I2-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UJHI-0426-SM-3DB8Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.867855
r6 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.02316
BRD-K64890080_BI-2536_LNCAP_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KA-75-LP02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.361769
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PX3G-0008-SM-48U2L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.169
Piriform-amygdalar area, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26829
BRD-K76984291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02392
GSE154767_4_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BC-54-ON71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.237835
BRD-K70401845_erlotinib_MCF10A_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE150349_0_v_1_msx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K81418486_vorinostat_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC7673140-41467_2020_19575_MOESM4_ESM.xlsx-Data_S1d-List_of_2302_of_genes_differentially_regulated_by_SOX2_FDR_0_1_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4516	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GTEX-PX3G-1626-SM-2S1PT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38113
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
UF-14-LK87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.569448
HCC366	CCLE Cell Line Gene Expression Profiles	-1.0	-1.67853
GTEX-X261-3226-SM-3NMC3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3804
PLEKHG3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K56783915	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55446
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.69169
HA-42-TE64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.237757
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.30953
pancreas_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.50156
HS822T	CCLE Cell Line Gene Expression Profiles	1.0	1.66714
BRD-K73261812_-666_LOVO_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
valproic acid_homo sapiens_gpl96_gds1050	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K86817746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05937
betonicine-2207	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-QCQG-0426-SM-48U29	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887946
FLOT1	Pathway Commons Protein-Protein Interactions	1.0	null
TC-95-IR96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.597771
GSE165647_5_v_3_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Connecting tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.727
NCI-H1155	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.85742
SEPT11	Pathway Commons Protein-Protein Interactions	1.0	null
MB-32-LQ97_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.243136
GSE95302_2_v_3_tamoxifen_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Barrington's nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31417
SNU-283	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.24723
AB-71-CI37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.219775
GTEX-PSDG-1026-SM-48TCV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826664
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	72.4636
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC11237033-41419_2024_6873_MOESM3_ESM.xls-Supplementary_Appendix_2-CEBPD_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE215109_0_v_2_ep400_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-W5WG-2426-SM-4LMI6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.867018
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K29628583	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6714
folic acid_homo sapiens_gpl2700_gds3656	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE199255,GSE199356_4_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ES-A2HT-01A-12R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GD-59-OG21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.316401
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6906
BC-56-CP81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.299293
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hypoglossal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.49612
Lung squamous cell carcinoma_LUSC_TCGA-37-4141-01A-02R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COPE	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
substantia nigra compacta, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55231
H3K4me1_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCIH747	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63198
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5953
CRCGN009_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.49898
protein transport	GO Biological Process Annotations 2015	1.0	null
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RAB1A	Pathway Commons Protein-Protein Interactions	1.0	null
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_3_TurboID_1hr_ERM_proteome-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
LE-40-JW92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.440104
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.98814
midbrain raphe nuclei	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.833706
PMC4728380-ncomms10153-s8.xlsx-High_affinity_MYC_Targets-Unnamed_0_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
Main olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38947
ZWINT	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K36566880	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60881
GTEX-OHPK-1626-SM-2YUN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05415
GTEX-X4XY-1726-SM-46MVO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.971945
PMC6379364-41598_2018_37489_MOESM2_ESM.xlsx-Sheet2_DESeq_MSC_vs_fibroblast-DESeq_MSC_vs_fibroblast_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
STAM	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN015_HEPG2_48H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.46839
DE-03-NP53_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.208617
GTEX-T2IS-2626-SM-32QPP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.81935
PMC9013128-NIHMS1795992-supplement-4.xlsx-SKmel147_ARID2_KO_Upregulated-Gene_name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
physiological	GeneRIF Biological Term Annotations	1.0	null
BRD-K64890080_BI-2536_MCF10A_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-A5B5-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
salivarygland_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.21047
jf5	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.58
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U412-0326-SM-3DB9L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14031
CRCGN017_MCF10A.TP53.M_24H:G11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.95507
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27779
BRD-K52037352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60767
BRD-K06519744	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17851
H3K79me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942822
PC-18-VX23_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.335689
intrinsic component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.134227
GSE96777,GSE96778_3_v_2_zbtb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE183271_1_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
malignant glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.158266
lateral part of MM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38651
GTEX-U8XE-0008-SM-4E3K4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843802
MB-72-YK93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.384739
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SEL1L	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-Q734-0426-SM-48TZX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70259
GSE57871_5_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XV7Q-0226-SM-4BRVL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20331
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
CD-05-PU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.418356
ASPSCR1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K03341571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.34466
GTEX-WHSE-0011-R3A-SM-3P5ZM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903197
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00872
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
FC-96-WR45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.304767
GBF1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K36me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K01263144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55336
KB-78-BE93_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.525145
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K17649115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35906
SLC30A9	Pathway Commons Protein-Protein Interactions	1.0	null
AD-51-SS86_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.408545
A3/KAW	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.99574
RUNX3	ENCODE Transcription Factor Targets	1.0	null
PRKCD	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A7Q0-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NOL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06877
dexamethasone_rattus norvegicus_gpl1355_gse29912	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10253
ANXA5	Pathway Commons Protein-Protein Interactions	1.0	null
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.82361
SNU-423	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0836
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.3542
BRD-A04975445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38083
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MOG-G-CCM	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.94211
cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GATA3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PTK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00338969
Rectum adenocarcinoma_READ_TCGA-CL-5918-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE154197_1_v_0_ints13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE198165,GSE198166_0_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN010_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.55375
Ventricular hypertrophy_Myocardial tissue_GSE4678	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.27119
BRD-K46701848	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55936
GTEX-WL46-3026-SM-3LK7Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13501
k562	HPA Cell Line Gene Expression Profiles	-1.0	-1.0609
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06738
BRD-A22502289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3808
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.708809
RANGAP1	Pathway Commons Protein-Protein Interactions	1.0	null
Brain - Putamen (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.2265
posteromedial cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42798
GSE149943_2_v_3_cd8a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
diethylstilbestrol_rattus norvegicus_gpl1355_brown norway_gds2913	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
High grade glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.109
tissues	GeneRIF Biological Term Annotations	1.0	null
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CE-02-FZ80_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.247976
BRD-K39120595_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
VPS16	Pathway Commons Protein-Protein Interactions	1.0	null
SK-N-SH	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05767
BRD-K37956279	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89079
GSE229070,GSE229071_0_v_2_sotorasib_human	RummaGEO Drug Perturbation Signatures	1.0	null
mantle zone of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01114
ventral posterior medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.916564
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.21906
BCL7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03566
telencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
CA-60-LK14_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.231662
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K64857848_XMD-885_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN014_HEPG2_3H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.36379
MKN45	CCLE Cell Line Gene Expression Profiles	-1.0	-1.70268
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE180147_0_v_1_itga5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FD-79-TC61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.899831
CRCGN017_MCF10A.TP53.M_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.59103
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE195559_6_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC3470785-NIHMS377161-supplement-3.pdf-350-SP2_SP2	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-53-7813-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13141
ALMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44954
temporal muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.226
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE135686_2_v_3_etomoxir_human	RummaGEO Drug Perturbation Signatures	1.0	null
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.51691
GTEX-N7MS-0008-SM-4E3JI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27625
GSE196540,GSE196542_4_v_0_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE48812_8_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TRAPPC3	Pathway Commons Protein-Protein Interactions	1.0	null
ZFYVE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57654
hydralazine-2349	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
superficial stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42216
Lung squamous cell carcinoma_LUSC_TCGA-22-A5C4-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SE5C-0008-SM-4B64J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986706
XE-29-LT20_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.470289
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Parasubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.93317
BRD-K50387473_XMD-892_HCC515_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_6045_KD_NONO_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GC-07-UO80_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.393524
ASAH1	Pathway Commons Protein-Protein Interactions	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
CRCGN010_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.73128
GSE193258,GSE193259_9_v_8_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBC1D4	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K64890080_BI-2536_BT20_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PPP1CA	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AI-0226-SM-48U1D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68938
cefalexin-1273	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CE-00-EK89_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.225035
GTEX-OXRN-1726-SM-3NM9B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37659
BRD-K08109215_I-BET_HCC515_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DD-44-OX00_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.369034
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.22498
GTEX-PLZ5-1526-SM-3P5ZX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26352
SNX4	Pathway Commons Protein-Protein Interactions	1.0	null
GSE144231_3_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
XE-69-AT35_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.383923
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE233049_1_v_3_atf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216540_10_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K91290917_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Pancreatic_Islets	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.217
HES5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74298
CRCGN012_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5057
BRD-K69035249	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50635
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.605
VEZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.1695
NE-37-JX51_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.230674
midbrain reticular formation	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04532
BRD-K04568082	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24703
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.75499
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r8 part of linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26069
CNN2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K88278225_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hematopoietic cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.865719
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC3966871__F3	PFOCR Pathway Figure Associations 2024	1.0	null
CRCGN009_HEPG2_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.11116
hsa-miR-3199	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
H3K9me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE118794_2_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.34518
NC-27-AD53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.74765
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4673
BRD-K08799216_pelitinib_PC3_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-UTHO-3126-SM-3P5ZB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13274
YD-49-HM53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.623873
SPI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34038
Autonomic nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.485
PMC7576810-41419_2020_3099_MOESM9_ESM.xlsx-MS_analysis_EVI1-WT_vs_EVI1-S43-Unnamed_0_MECOM	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
LAMP1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A19037878_trichostatin A_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
WC-59-RG09_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.201678
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KIF4A	Pathway Commons Protein-Protein Interactions	1.0	null
WM983B	DepMap CRISPR Gene Dependency	1.0	2.38015
intermediate stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01707
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K17743125_belinostat_HA1E_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
UACC62_SKIN	CCLE Cell Line Proteomics	1.0	2.61519
BRD-K26790127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61157
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
locus ceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17363
H3K79me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
creb1_22108299_heart_left_ventricle_lof_mouse_gpl1261_gds3660	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.087149
HCC1143_BREAST	CCLE Cell Line Proteomics	1.0	3.17257
gracile nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.911625
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE152441,GSE152442_1_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
ANXA11	Pathway Commons Protein-Protein Interactions	1.0	null
DF-00-BU08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.220273
SEC31A	Pathway Commons Protein-Protein Interactions	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A4XK-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K12709183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50023
TE-15-RO34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.297351
GSE125014_1_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ERLIN1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN011_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.53545
PD-70-VS77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.740107
AA-59-HG56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.389795
H3K9ac_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Subparaventricular zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36407
BRD-K56343971_vemurafenib_PC3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSK3B	Pathway Commons Protein-Protein Interactions	1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_Deficiency_GDS4856_318_mouse_Soleus skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
icSARS CoV_72Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.96783
CE-96-GH46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.683078
hsa-miR-3153	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20039
ELK3-25401928-HUVEC-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K78907463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6553
HNT-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.863733
SIX5	ENCODE Transcription Factor Targets	1.0	null
liminal part of the r6 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33348
CRCGN015_MCF10A.WT.HP_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.60761
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.0553
AB-12-PP61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.627206
RBPJ	ChEA Transcription Factor Targets	1.0	null
Saracatinib	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.53
GSE117730,GSE117732_0_v_2_apobec2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZD-18-MI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.742272
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
SNU61_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	2.73656
GSE240027,GSE240030_5_v_0_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.998445
BRD-K49865102_PD-0325901_A375_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE210101,GSE210114_6_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.846159
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.83093
JC-06-ED36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.91623
Head and Neck squamous cell carcinoma_HNSC_TCGA-UP-A6WW-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE178255_1_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
protoveratrine A-2144	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.17
BF-10-IO69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.221284
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.73745
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOS	CCLE Cell Line Gene CNV Profiles	1.0	2.2094
AE-13-CX28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.484643
RHEB	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC25A33	Pathway Commons Protein-Protein Interactions	1.0	null
PMC9529122-pone.0274785.s002.xlsx-S1_Table-S1A_Table_Differentially_expressed_genes_in_HeyA8_overexpressin_ZNF521_vs_HeyA8_control_cells_ZNF521	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K93008833	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.27266
BRD-K60509482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91157
EE-98-PF86_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.77181
CRCGN009_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.00487
SUDHL1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73192
Lung adenocarcinoma_LUAD_TCGA-50-5044-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF1_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r7 part of the basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48974
icSARA deltaORF6_54Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.61896
BRD-A38030642_cyclosporine_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE185163_5_v_2_clic4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE214212_2_v_1_chd6_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K21327356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18163
18310505-TableS7	GeneSigDB Published Gene Signatures	1.0	null
BRD-K96322674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.72797
aspects	GeneRIF Biological Term Annotations	1.0	null
BRD-K37890730_Camptothecine (S,+)_PC3_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CB-49-OG36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.0143
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.23833
ZBTB11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4689
SCCOHT1	DepMap CRISPR Gene Dependency	1.0	2.8041
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07428
BRD-K74236984_UNC0321_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE188570,GSE188571_5_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:G17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09985
USF1_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AH-0008-SM-48U2J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45054
ELF1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K36198571_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ATF3_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.507525
NCI-H2009	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.93416
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DC-43-KF54_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.248581
smoothmuscle_8a	HPA Tissue Sample Gene Expression Profiles	1.0	1.06092
UNC93B1	Pathway Commons Protein-Protein Interactions	1.0	null
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Penis_Foreskin_Melanocyte_Primary_Cells_skin03	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.03561
GSE151782_1_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DB-34-QA60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.314729
MCF7_Belinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00813819
CA-66-YB17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.207373
RSF1	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25029
GTEX-R55D-0626-SM-3GAD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.834809
hippocampus (hippocampal formation)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.51428
hsa-miR-1587	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
G protein-coupled receptor dimeric complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.466
FSCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24766
ZMIZ1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE224556,GSE224557_6_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-REY6-1126-SM-48FDU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969526
membrane part	GO Cellular Component Annotations 2015	1.0	null
YY1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K14704318_7722075_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27ac_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
amino acid transport	GO Biological Process Annotations 2015	1.0	null
GSE141624_3_v_0_cocaine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.878719
JJ012	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00384
BRD-K81916372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20803
Lung adenocarcinoma_LUAD_TCGA-91-A4BC-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG231	DepMap CRISPR Gene Dependency	1.0	4.04199
Prostate adenocarcinoma_PRAD_TCGA-HC-7738-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
GTEX-N7MT-1026-SM-3TW8T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921424
GTEX-QV31-1426-SM-2S1QD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.36245
HT144SKINFV2	DepMap CRISPR Gene Dependency	1.0	2.44104
GSE161055,GSE161056_1_v_0_hira_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TEC	Pathway Commons Protein-Protein Interactions	1.0	null
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
QF-71-QI30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.491974
SNX5	Pathway Commons Protein-Protein Interactions	1.0	null
lytic vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K08109215_I-BET_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
localisation	GeneRIF Biological Term Annotations	1.0	null
CRCGN014_HEPG2_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4627
GSE174701_4_v_7_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
CEBPB-24764292-MC3T3-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
786	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.00527
GC-08-VP20_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.528252
CRCGN013_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.4759
CRCGN014_HEPG2_24H:M17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.0745
BRD-K81418486_vorinostat_SW948_6.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TOM1	Pathway Commons Protein-Protein Interactions	1.0	null
Simultanagnosia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.058
CBX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11993
mediodorsal nucleus of thalamus_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.53312
GSE147876,GSE147877_4_v_7_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-SUCS-0726-SM-4DM7J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887566
trimethoprim-2345	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RPMI-7951	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.914836
autonomic nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.05723
H3K9me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CE-15-YU05_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.215369
NCIH727	CCLE Cell Line Gene CNV Profiles	1.0	1.44142
Rectal Mucosa Donor 31	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.70408
18535662-TableS2c	GeneSigDB Published Gene Signatures	1.0	null
BRD-K87794979	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79192
BRD-K06750613_-666_PC3_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
trichostatin A-1421	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE205163,GSE205164_1_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z2-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.TP53.M_24H:E16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.15265
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A449-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	10.0
BRD-K36363294_I-BET151_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K01850737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21227
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A25687296_-666_ASC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Minor Salivary Gland	GTEx Tissue Gene Expression Profiles 2023	1.0	0.953552
BRD-K89366259	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.13602
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4822-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.582922
NCIH1568	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43846
EF-33-IW50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.239167
CRCGN016_MCF10A.TP53.M_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.02853
ATP6V1B2	Pathway Commons Protein-Protein Interactions	1.0	null
IZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15647
Entorhinal area, medial part, dorsal zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21602
DD-89-HG56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.215034
POLR2A	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFG7-0726-SM-3GIKO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08393
H3K27me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-A02481876_Importazole_PC3_24.0_h_60.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE216326_2_v_0_sulodexide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XLM4-0011-R6A-SM-4AT4B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47827
REST_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AB-35-RU30_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.240105
LSM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13145
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K82928847_rocilinostat_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-593	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Amygdala	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
USF1_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K12184916_NVP-BEZ235_MCF10A_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC8355885-gutjnl-2020-320652supp004.xlsx-RALY_KD_mRNA-seq-Table_3_RALY_Knockdown_in_HCT116_cells_mRNA-seq_log2_FC_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K81418486_vorinostat_HT29_24.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.61859
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SMAD4-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K06678077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.66946
GSE112761,GSE112767_4_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.258877
BRD-K01436366_XMD-1150_SKBR3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE118939_1_v_0_nras_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A80502530_-666_ASC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SNB75	BioGPS Cell Line Gene Expression Profiles	1.0	1.01615
EB1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.18582
HS 839.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.02944
BF-29-LU75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.268372
BRD-K81418486_vorinostat_MCF7_6.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PPP5C	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.937102
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JF-84-QZ64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.200933
MAPKAPK3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K09951645_dabrafenib_A375_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
STXBP3	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H2818	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.03284
FF-22-NB12_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.360039
Anterior cingulate area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24022
MAX_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fat_8a	HPA Tissue Sample Gene Expression Profiles	1.0	0.959353
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K36363294_I-BET151_HA1E_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8428-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE176555,GSE176556_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ME-11-OJ38_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.373931
pheniramine-4012	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Capsazepine	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.54
GSE142430_3_v_0_prmt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PML_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K21680192_mitoxantrone_HT29_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FE-56-PV35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.31612
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03236
BRD-K28907958_-666_MCF7_24.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AF-80-GK24_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.915417
Perinuclear endoplasmic reticulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.874
EE-03-SG02_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.746498
GSE65617_2_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HE-80-BQ08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.296844
VZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.98647
SNU-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02719
superficial stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6948
sulfadiazine-1852	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CD-80-ZD47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.484865
HUH7	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
P68-20966046-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RPMI7951	CCLE Cell Line Gene CNV Profiles	1.0	1.62546
BRD-K75588273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05334
BRD-K76694128_DCC-2036_A375_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K89399989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.24887
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.23829
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K16682693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60473
H3K79me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPP1CB	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN009_HEPG2_24H:H04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.07353
RAB11B	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K34677894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11636
ELMO3	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBA7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00721837
MNAT1_Deficiency - Ablation_GDS2561_690_mouse_Heart - 4 week old	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
AE-13-CX28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.811385
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3189-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GTEX-X4EP-0011-R2B-SM-3P625	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938052
QF-05-OL72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.267359
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HH-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE157960_2_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NRBP1	Pathway Commons Protein-Protein Interactions	1.0	null
HCFC1	ENCODE Transcription Factor Targets	1.0	null
Sarcoma_SARC_TCGA-DX-A3UC-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HA-27-FV67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.318445
BRD-A19037878_trichostatin A_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.159
QA-50-YO37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-5.98677
ELF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C2CD4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17472
MOGGCCM	CCLE Cell Line Gene Expression Profiles	1.0	1.55923
GSE193258,GSE193259_5_v_8_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-330-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
GSE157894_1_v_0_cystine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AD-18-XC14_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.329007
AB-35-RU30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.223913
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AD-29-IG16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.430382
Liver Cirrhosis, Experimental	DisGeNET Gene-Disease Associations	1.0	null
SG in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24127
DNTTIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70118
estradiol-6200	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
u2-os cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.695354
LGR5	Pathway Commons Protein-Protein Interactions	1.0	null
Basal ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HA-22-CY42_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.453645
BRD-K24035524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09092
BRD-A19037878_trichostatin A_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
IGROV1	DepMap CRISPR Gene Dependency	1.0	8.81572
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K50146114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03807
CRCGN008_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.44655
BET1	Pathway Commons Protein-Protein Interactions	1.0	null
CA-60-RU13_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.274825
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K68086276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0943
BRD-A18328003_GDC-0980_PC3_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K39526528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.28232
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
prilocaine-2352	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KC-17-YN77_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.356843
USH1C	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FLNB	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-520d-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
urapidil-5295	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.877578
PROCR+ progenitor cell_Small intestine_Human	CellMarker Gene-Cell Type Associations	1.0	null
FAM204A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40612
BF-29-LU75_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.368947
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
RKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.914473
BRD-K49075727_nintedanib_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE96641_5_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.58902
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCFCP2L1-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CNOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19402
H3K4me1_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Encephalomyelitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.162
PMC10534007-Table_2.xlsx-S1_overlap_MSC_up_B_V-438_common_elements_in_BFTC905_MSC_up_and_VM-CUB1_MSC_up_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
HS571T	CCLE Cell Line Gene Expression Profiles	1.0	1.88991
BRD-K68548958_-666_HA1E_24.0_h_20.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
AA-23-FM46_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.524067
GSE185944_2_v_3_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LGE-VZ border region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.961223
BRD-K00337317_NU-7441_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
halcinonide-3680	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-QDT8-0008-SM-48U2F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18699
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.55225
PE-86-SC73_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.262682
CRCGN015_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	10.0
GSE130690,GSE130692_1_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.WT.HP_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.04385
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MO-1626-SM-32QOM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0619
BRD-K49865102_PD-0325901_A375_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE211126_3_v_4_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
posteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55112
GSE57871_1_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
7423_RPAP2_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.13428
AIDA	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K13190943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87556
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
RAB13	Pathway Commons Protein-Protein Interactions	1.0	null
isotretinoin-7438	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
UM-UC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3129
DBNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35873
PK-59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14109
SB-29-ZH97_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.516973
MXI1	ENCODE Transcription Factor Targets	1.0	null
GSE218580_1_v_5_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MAX	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE227592_6_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A25736793_everolimus_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE261563_2_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MARK2	Pathway Commons Protein-Protein Interactions	1.0	null
AF-28-FX20_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.367914
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DGKA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00551295
Melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.156
GTEX-UTHO-0011-R2A-SM-3GIKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23793
GTEX-PWOO-1526-SM-48TCK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.928372
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.61068
BRD-U64521890_XMD16-144_BT20_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
20860821-TableS5	GeneSigDB Published Gene Signatures	1.0	null
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K82930531	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36099
naftifine-2974	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE184892_6_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE126345_9_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03672
STAG1	Pathway Commons Protein-Protein Interactions	1.0	null
r8 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30158
CRCGN016_MCF10A.TP53.M_24H:D19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.92088
Perturb_2035_KO_Pth1r_SRP341470	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-18.8539
Avian pallium	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SC-72-YW56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.24791
PPARalpha_OE_GDS2289_244_mouse_Skeletal muscles	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC10117100-msphere.00056-23-s0008.xlsx-2B-Supplementary_Table_S2B_mRNAseq_analysis_genes_significantely_downregulated_upon_E2F4-5_knockdown_in_38HK_E2F4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R55G-0008-SM-48FEX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39705
PMC10592471-NIHMS1912771-supplement-7.xlsx-D-Enh_vs_AA-all_DE-Aza_atRA_DE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
OA-15-DB28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.279819
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A35869383_ibrutinib_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SEPT7	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K24004917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28022
amygdaloid complex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.35827
SNX1	Pathway Commons Protein-Protein Interactions	1.0	null
496100399_PCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.28103
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
VZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11716
BRD-K96981233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.15359
r6 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00484
WB-82-EL69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.717674
GSE152699,GSE152723_0_v_2_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN009_HEPG2_24H:N19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.55221
ZNF143	ENCODE Transcription Factor Targets	1.0	null
CRCGN015_MCF10A.WT.HP_24H:C04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.70665
BRD-K81418486_vorinostat_VCAP_6.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN017_MCF10A.TP53.M_24H:I01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.14515
KDM5B_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.21045
GSE80446_0_v_1_anakinra_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:D22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2733
posteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2613
NCI H322M	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.915802
BRD-K44935022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.42429
GSE239688_2_v_5_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VM-A8C9-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.114329
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_GSC-Unnamed_1_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
E2F6	ENCODE Transcription Factor Targets	1.0	null
GTEX-XYKS-0002-SM-4BRWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836467
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.53141
medial mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36214
CRCGN011_HEPG2_24H:L20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.88855
Lung adenocarcinoma_LUAD_TCGA-55-8514-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.12353
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.8169
BRD-K42918627_GSK-2126458_A549_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE100316_5_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K76672835	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56589
EE-03-SG02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.53476
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PC3	CCLE Cell Line Gene Expression Profiles	-1.0	-1.55225
AB-84-PK04_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.713762
GTEX-S95S-1426-SM-2XCDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27285
RABEP1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K01436366_XMD-1150_LNCAP_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.3632
DA-83-IZ87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.392145
GSE178255_2_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K39687892_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RINT1	Pathway Commons Protein-Protein Interactions	1.0	null
NR2F2_02_19	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60303
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
VB-92-JQ72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.89553
H3K36me3_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OA-12-SU22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.202353
HC-11-RK51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.34269
BRD-K09499853_KU 0060648 trihydrochloride_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AE-32-DP61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.267323
BRD-K01436366_XMD-1150_MCF10A_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
USF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.70426
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.10792
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JE-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KRTCAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3673
BC-15-EL49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.346142
BRD-K99300752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.20519
hsa-miR-512-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
BRD-K95588139	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07019
MTOR	Pathway Commons Protein-Protein Interactions	1.0	null
NFE2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNOS-1626-SM-3NMA4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902459
GTEX-NL4W-0011-R8a-SM-2I3G4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15782
BRD-K01225247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53053
BC-43-JW95_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.633507
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_3H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.296
NOMO-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.44413
BRD-K12502280_TG-101348_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE242290_1_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
SIRT6	ENCODE Transcription Factor Targets	1.0	null
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K26866198	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00708
EXOC2	Pathway Commons Protein-Protein Interactions	1.0	null
MYC-28411283-MDA231-LM2-4175-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
Leukemia_chronicMyelogenousK-562	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.904465
70Z/3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.183
CD-16-KY17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.357011
SB-89-QK94_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.24306
CTCF_fibroblast of mammary gland_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-0826-SM-3NM8Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6848
retrotrapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.3781
GTEX-XUW1-0008-SM-4BOQH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856015
CRCGN017_MCF10A.TP53.M_24H:L20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3434
GSE242647_2_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BB-83-ZM06_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.535071
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CE-37-XI06_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.482523
BRD-A19037878_trichostatin A_HCT116_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.23492
TE-16-VT54_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.240475
hsa-miR-4438	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GSE176008_0_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ATR_knockdown_140_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.75126
BRD-K24496482_SB590885_A375_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K36me3_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.860235
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.21906
BRD-K13788250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4342
GSE158834_0_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
FA-36-VA24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.973703
Perturb_16531_KO_Cdk8/Cdk19_SRP351257	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.32872
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.32554
GSE111245_0_v_1_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE226249_2_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GP2D	CCLE Cell Line Gene Expression Profiles	-1.0	-1.55137
PMC11551338-pnas.2411189121.sd01.xlsx-FXR-Unnamed_0_NR1H4	Rummagene Transcription Factor Associations 2026	1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AH-1626-SM-3GAF8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49455
BRD-K48593237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06376
H3K36me3_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tiapride-2331	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HB-75-KT12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.573894
lymphocyte	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K00337317_HY-11006_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PKN2	Pathway Commons Protein-Protein Interactions	1.0	null
RFX5	ENCODE Transcription Factor Targets	1.0	null
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
BRD-K86004174	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09865
GSE211983_0_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GD-46-OD81_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.410464
BRD-K00537235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74049
PA-TU-8988S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.981448
r7 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33032
GB-57-XV52_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.342264
BRD-K03063480_PF-477736_MCF10A_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.966711
BRD-K68202742_trichostatin A_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SLC25A25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17019
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
macromolecule localization	GO Biological Process Annotations 2015	1.0	null
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02401
GSE144115_2_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BE-82-TS38_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.366444
GSE212486,GSE212488_0_v_1_gata4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE201239_3_v_2_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE101112_6_v_4_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T6MN-0126-SM-32PLP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02998
ETS1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4697-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE198165,GSE198166_7_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K59469039_AG-879_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K98087319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11336
H3K36me3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
XPOT	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN016_MCF10A.WT.HP_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.19306
BRD-K46373671_-666_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.89214
gliclazide-2870	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE154081_3_v_0_sildenafil_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PD-70-VS77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.52506
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CB-99-NG16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.200467
TOMM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17877
SD-69-QA40_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.362785
CE-96-GH46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.41711
BRD-K50423606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21566
BRD-K49865102_PD-0325901_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A6W2-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX1	ChEA Transcription Factor Targets	1.0	null
GTEX-QLQ7-1726-SM-2S1QQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.94701
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.461
BRD-K12343830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56264
COLO-320-HSR	GDSC Cell Line Gene Expression Profiles	1.0	1.60559
GTEX-XXEK-0726-SM-4BRWF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900762
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK4_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-3126-SM-4AT6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26099
CCDC50	Pathway Commons Protein-Protein Interactions	1.0	null
ZFYVE1	Pathway Commons Protein-Protein Interactions	1.0	null
PANC 05.04	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.93025
GSE217873_1_v_0_nusap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE138815,GSE138817_0_v_2_kdm6a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
amygdaloid complex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.97124
BRD-K38713368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06066
VZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.35853
BRD-K12502280_TG101348_A549_6.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-OOBJ-1026-SM-3NB2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.00569
SNU5	CCLE Cell Line Gene CNV Profiles	1.0	1.63085
GSE210885_2_v_4_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
bclxlbcl2	GeneRIF Biological Term Annotations	1.0	null
AC-36-TL21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.640324
CEBPB_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HD-26-KX74_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.325613
LN-229	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.877578
PMC4224449-pone.0112193.s009.xlsx-PPI_MODULES_CLEAN_MAP_merg_OUT-Symbol_TCF23	Rummagene Transcription Factor Associations 2026	1.0	null
IC-80-CT90_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.540543
Acute Myeloid Leukemia_LAML_TCGA-AB-2811-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SARS-CoV_72Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.67972
SNRPD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5949
CRCGN016_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.99312
superficial stratum of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18251
SEMK2	DepMap CRISPR Gene Dependency	1.0	2.06931
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04803
alpha-ergocryptine-3817	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ATG7	Pathway Commons Protein-Protein Interactions	1.0	null
PBX3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NELFE_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE120595_5_v_4_arid2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K15997423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6607
CNOT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14912
GTEX-Q734-2026-SM-3GADA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2705
GTEX-PWN1-1626-SM-2S1OL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91912
USF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K94962552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27798
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7X8-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K36363294_I-BET151_HCC515_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
JA-95-PQ25_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.601711
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
BRD-A19037878_trichostatin A_AGS_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE120413,GSE120447_0_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
intermediate stratum of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00782
GSE199874_4_v_5_gabpb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H2227	GDSC Cell Line Gene Expression Profiles	1.0	3.05355
QD-57-GT11_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.332964
HCC1359	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.931116
AB-09-YX02_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.334156
H3K4me3_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K36363294_I-BET151_HCC515_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NC-76-YX69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.221489
SAR1A	Pathway Commons Protein-Protein Interactions	1.0	null
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32916
GSE186440,GSE186443_3_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
BC-75-FA82_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.446172
CH157MN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36419
PMC8724844-bt-30-1-98-supple2.xlsx-Hallmark_pathways-CEBPD_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
PLEC	Pathway Commons Protein-Protein Interactions	1.0	null
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057166
DD-55-AU25_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.242798
BA-60-DR11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.211851
BRD-K30252238	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.19941
GSE248045,GSE248046_0_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4731-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
BRD-K88437756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18752
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.96102
GSE60217_1_v_10_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
interacting	GeneRIF Biological Term Annotations	1.0	null
FF-46-OR35_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.218184
Entorhinal area, medial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.0527
GTEX-WFG7-0926-SM-4LMK7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922411
BRD-K67844266_MLN4924_A375_24.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01536	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.14235
JE-55-OJ53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.214164
VPS35	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GOSR1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE145476_2_v_0_hopx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K14216332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20146
STARD5	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K71716722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58919
doxorubicin_homo sapiens_gpl570_gse46493	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20P-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE102870_3_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ventral tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.14916
BCL3-23251550-MUSCLE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
FF-22-NB12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.3012
IC-80-CT90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.265444
CRCGN014_HEPG2_24H:G03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.7567
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HB-92-XE24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.367098
AE-00-WU78_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.488628
7751_SEC61A1_P1	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.78922
Perturb_6059_KD_RBM26_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
SACM1L	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-S7PM-0526-SM-3NM92	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58797
hsa-miR-4756-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
NFYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.346
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_Jurkat_LPS_vs_DC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN017_MCF10A.TP53.M_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.261
ZB-72-PE17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.287638
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08257
ELF1	ENCODE Transcription Factor Targets	1.0	null
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.913092
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HuP-T4	GDSC Cell Line Gene Expression Profiles	-1.0	-1.48274
GSE172295_0_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K31354456	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20526
SUPM2	CCLE Cell Line Gene CNV Profiles	1.0	1.9049
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.846136
BRD-K58844095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85274
AA-70-VU13_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.312615
BRD-K25408656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0708
CRCGN008_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.95545
BE-31-XV38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.720138
BRD-K67844266_MLN4924_HCC515_24.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ARCN1	Pathway Commons Protein-Protein Interactions	1.0	null
Hippocampal mossy fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.729
PLEKHH1	Pathway Commons Protein-Protein Interactions	1.0	null
TT	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64355
thioperamide-3055	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K76976010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35175
DGKQ	Pathway Commons Protein-Protein Interactions	1.0	null
GSE88819_11_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RAB8A	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K91784140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08578
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EGR1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GINS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50736
VAV2	Pathway Commons Protein-Protein Interactions	1.0	null
FF-34-KW62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.333156
periventricular stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16813
BRD-K15108141_gemcitabine_SKM1_6.0_h_0.08_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Arcuate hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.63133
membrane	GeneRIF Biological Term Annotations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67W-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
imatinib_homo sapiens_gpl96_gds3044	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FB-67-OY39_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.377424
CRCGN015_MCF10A_48H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1995
NR0B1-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
cerebral hemisphere	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
superficial stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.96771
GTEX-N7MS-0011-R1a-SM-2HMJG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16909
difenidol-2374	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.751501
Limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K81439435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2499
CC-90-EX35_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.910637
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054383
BRD-A39646320_H7270_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-VUSG-0003-SM-3NMDK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28187
BRD-K75821161	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0476
GSE116930,GSE116935_1_v_0_hes7_human	RummaGEO Gene Perturbation Signatures	1.0	null
FA-43-TP28_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.304675
Neuroblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.485
Flocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36214
UQCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02091
BRD-K06308228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88526
BRD-K79090631_CGP-60474_MCF7_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RM-A68W-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15499
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3426-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT6	MotifMap Predicted Transcription Factor Targets	1.0	null
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148066,GSE157787_5_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Mesothelioma_MESO_TCGA-SC-A6LP-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03064
ND-15-RC31_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.705905
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051157
POLR2A_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAD2L1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K76812105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26072
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE142210_3_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
IQGAP2	Pathway Commons Protein-Protein Interactions	1.0	null
HaCaT cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.952
DA-27-BW40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.217473
BD-68-ZT55_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.251835
BRD-K64890080_BI-2536_BT20_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE169205_4_v_7_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
ACOT11	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K76742876	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42056
LN18	BioGPS Cell Line Gene Expression Profiles	1.0	1.13196
KMS18	CCLE Cell Line Gene Expression Profiles	-1.0	-1.83903
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.838003
BRD-K81418486_vorinostat_MCF7_24.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
colecalciferol-2436	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PC-44-DH10_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.504134
RABAC1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K31390971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78997
AB-09-YX02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.292201
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.864701
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:J07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.91093
DF-95-CY55_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.273537
GA-47-MH68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.413533
PGAM5	Pathway Commons Protein-Protein Interactions	1.0	null
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.89555
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cerebellum	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.41207
EGR1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_6015_KD_FYTTD1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
CTCF_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBEW-1326-SM-4AT63	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45217
PCNX3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00548341
BRD-K89514545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27813
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ND-15-RC31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.29998
CRCGN015_MCF10A_48H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.50328
GTEX-S95S-0226-SM-4B656	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58365
GSE239688_4_v_0_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AC-84-QG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.27787
LY-294002-1180	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KB-72-ID36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.226793
BRD-K91041732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4121
H3K36me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IG-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KA-78-TY66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.226167
GTEX-W5WG-1926-SM-4KKZK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934021
GB-84-KP45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.37476
CRCGN016_MCF10A.WT.HP_24H:D20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3101
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
AC-36-SY22_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.223626
Twist2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8894
BRD-K09499853_KU 0060648 trihydrochloride_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
thorax	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055113
DNM2	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN015_HEPG2_48H:I07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.32297
GTEX-T5JW-1826-SM-3GAE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14652
paraventricular nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.871854
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K88378636_withaferin-a_PC3_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN013_HEPG2_24H:B13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.40324
AHNAK	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K30097969_itavastatin ca_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN016_MCF10A.TP53.M_24H:E19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.20185
17823660-TableS2	GeneSigDB Published Gene Signatures	1.0	null
H3K27ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RANBP1	Pathway Commons Protein-Protein Interactions	1.0	null
GNA11	Pathway Commons Protein-Protein Interactions	1.0	null
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.1
JUN	ENCODE Transcription Factor Targets	1.0	null
CRCGN015_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.61332
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MYC_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE232564,GSE232566_0_v_2_nsd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-OLIG2_UNIQUE_DYS_GENES-NEUN_TLE_vs_TL_log2FoldChange_1_padj_0_1_OLIG2	Rummagene Transcription Factor Associations 2026	1.0	null
HCC44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.68161
GSE199660_1_v_0_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
YY1-33199912-293T-HUMAN-KIDNEYEMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
GA-28-SS67_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.00875
PMC10933434-44319_2024_69_MOESM2_ESM.xls-HRV16-UV_vs_MI-Associated_Gene_Name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5000-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K61401890_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K70518736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95092
SCARB2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K36me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE168097_3_v_2_epinephrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K22385716_LY 303511_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
VPS37B	Pathway Commons Protein-Protein Interactions	1.0	null
NRF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PF-39-DY68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.35334
C3A	CCLE Cell Line Gene Expression Profiles	-1.0	-2.63894
GSE198794_0_v_3_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE231799_2_v_1_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MZ in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38746
CRCGN011_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.81155
BRD-K81821040	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87523
Breast Neoplasms	CTD Gene-Disease Associations	1.0	1.03084
BRD-A19500257_geldanamycin_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8629-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE239844_1_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CHRNA9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00550856
CRCGN015_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	10.0
spanning component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.447656
ANP32A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18835
BRD-K93508241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.3766
CRCGN012_HEPG2_24H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.09864
BRD-K88395026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91116
BRD-K92093830_doxorubicin_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H650	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.93416
CRCGN012_HEPG2_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5057
DYNC1H1	Pathway Commons Protein-Protein Interactions	1.0	null
HS294T	CCLE Cell Line Gene Expression Profiles	1.0	2.41479
FC-20-EQ58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.805576
WC-49-TQ48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.203172
substantia nigra, pars compacta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21907
TRIM28_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KA-52-MX24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.221924
cellular_component	GO Cellular Component Annotations 2015	1.0	null
BRD-K66993610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00167
DNMBP	Pathway Commons Protein-Protein Interactions	1.0	null
embryonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.081526
GSE152441,GSE152442_1_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Fetal Kidney	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.59403
BRD-K12184916_NVP-BEZ235_MCF10A_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
subthalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.927233
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
colonrectum_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.20116
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55117
cisplatin_mus musculus_gpl339_gds3099	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K25312635	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6611
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K21025364_NVP-TAE226_A375_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K64890080_BI-2536_LNCAP_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7740-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K52154207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53758
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.866014
AU565	CCLE Cell Line Gene CNV Profiles	1.0	1.43072
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
ELF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:N03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.47719
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.861583
BRD-K45860594	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15928
CRCGN013_HEPG2_24H:L20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.55239
NUP93	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31976
hsa-miR-302d	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.10568
GSE217776,GSE217829_2_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	1.0	null
CCND1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K85606544_HKI-272_HCC15_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ARL2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TE-87-FM14_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.298681
mediodorsal nucleus of thalamus_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12706
LB-67-JK40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.274296
ANXA2	Pathway Commons Protein-Protein Interactions	1.0	null
intermediate stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30158
vincamine-3784	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN011_HEPG2_24H:G17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0244
mantle zone of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63245
GSE213588_8_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T8EM-0826-SM-4DM76	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903511
CRCGN017_MCF10A.TP53.M_24H:J04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2133
CRCGN016_MCF10A.TP53.M_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.27168
BE-25-UR78_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.20246
RS11846	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.07031
BRD-K81418486_vorinostat_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K13271778	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1205
YC-57-OY42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.600242
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.32359
TP73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21868
Penis_Foreskin_Melanocyte_Primary_Cells_skin01	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.31701
CRCGN009_HEPG2_24H:A18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15274
BF-69-DN58_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.253995
Amelanotic melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.079
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K42436189_AZ20_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-RVPU-0008-SM-3NM8B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886649
GSE244730_0_v_1_erlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MXI1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RIMS1	Pathway Commons Protein-Protein Interactions	1.0	null
UF-14-LK87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.979611
HC-86-IA49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.204968
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A680-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01348
avian pallium	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
exceptionally	GeneRIF Biological Term Annotations	1.0	null
GTEX-S341-0526-SM-4AD5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05006
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.31986
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.55661
BRD-K48999921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6871
X, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.30459
AD-40-WB93_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.447846
QA-07-KC40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.485574
BRD-K99252563_QL-XII-47_MDAMB231_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KC-48-OO62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.824531
CRCGN017_MCF10A.TP53.M_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.4355
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AB-74-VK99_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.330168
CAB39	Pathway Commons Protein-Protein Interactions	1.0	null
natamycin-7167	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC11461876-42003_2024_6975_MOESM3_ESM.xlsx-Supplementary_Data_1-Supplementary_Data_1_Differentially_Expressed_Genes_HSE_THP1_Vs_THP1_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
M059J	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.872777
GTEX-V1D1-1026-SM-4JBHE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44855
RAD21_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-7831-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PDCD6IP	Pathway Commons Protein-Protein Interactions	1.0	null
sulfadiazine-5098	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CF-97-KZ12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.583127
BRD-K76251351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.45206
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061519
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.861583
suprachiasmatic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.98443
CISD2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K85649685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72243
GTEX-S33H-1226-SM-4AD69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.984976
CRCGN015_HEPG2_48H:L02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.37588
H3K9ac_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:H10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.28069
CRCGN008_HEPG2_24H:C11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.88315
B800-850 antenna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.892
WRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1204
clathrin-coated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.157218
CEBPB_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
multiple	GeneRIF Biological Term Annotations	1.0	null
TAF1	ENCODE Transcription Factor Targets	1.0	null
VPS33B	Pathway Commons Protein-Protein Interactions	1.0	null
GSE118548_1_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K24496482_SB590885_MCF10A_3_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K04363234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.1561
PDS5A	Pathway Commons Protein-Protein Interactions	1.0	null
JB-89-SI60_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.224113
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K02708799_GSK-1059615_A549_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
WASF2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE213410_2_v_3_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
pancuronium bromide-4570	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EC-62-OE64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.389737
CRCGN012_HEPG2_24H:J20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.69719
Prostate adenocarcinoma_PRAD_TCGA-EJ-A65B-01A-12R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4498	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
SP1	ENCODE Transcription Factor Targets	1.0	null
peripheral portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25723
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0426-SM-2YUN6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.923614
POLR2A_GM18526_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61983
nefopam-2355	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K00337317_HY-11006_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC11551338-pnas.2411189121.sd01.xlsx-AHR-Unnamed_0_AHR	Rummagene Transcription Factor Associations 2026	1.0	null
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.92442
CRCGN016_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.18186
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EO-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAB7A	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K86797399_pracinostat_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CD14+_Monocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.47075
TO175T	CCLE Cell Line Gene Expression Profiles	1.0	1.44019
TIMM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29528
HS695T	DepMap CRISPR Gene Dependency	1.0	2.44056
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE160373_6_v_4_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
WD-62-UB45_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.256026
GDI2	Pathway Commons Protein-Protein Interactions	1.0	null
EC-01-PH79_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.296837
GSE216273,GSE216292_0_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
IV	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.879159
BRD-K77978259	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27059
LA-09-SS14_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.304378
GTEX-RM2N-0008-SM-48FF3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92831
SUPM2	DepMap CRISPR Gene Dependency	1.0	6.99786
BRD-K42805893_HG-14-8-02_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN016_MCF10A.WT.HP_24H:A21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02598
CPNE1	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCPAP	CCLE Cell Line Gene Expression Profiles	1.0	2.21252
traffic	GeneRIF Biological Term Annotations	1.0	null
NRF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UA-06-UV98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.275062
hsa-miR-4710	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GSE161800_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BD-61-OO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.640364
STOML2	Pathway Commons Protein-Protein Interactions	1.0	null
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.8408
NE-94-VE83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.62215
hydrocortisone_homo sapiens_gpl570_normal scar_gds3071	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JC-02-ZR15_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.405008
BRD-K71184289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01693
CRCGN014_HEPG2_3H:C08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.98966
LE-55-RW34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.399471
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.913503
CMK115	CCLE Cell Line Gene CNV Profiles	1.0	1.77513
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OD-03-CA36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.29604
amygdaloid complex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.986104
blood	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
RA-49-ZB08_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.438678
CRCGN011_HEPG2_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.84545
GTEX-XUZC-0926-SM-4BOQF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909966
NCI-H508	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.15785
CE-15-YU05_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.535298
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BD-69-GX17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.291059
GSE174498,GSE174500_3_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K49075727_nintedanib_LNCAP_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE193258,GSE193259_9_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
JE-04-LS32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.297329
RAB5B	Pathway Commons Protein-Protein Interactions	1.0	null
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.863733
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.4722
CRCGN014_HEPG2_3H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.06415
BRD-K17743125_belinostat_HA1E_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Colon - Transverse	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.43756
VB-92-JQ72_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.306666
TFAP2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	153.748
GSE157960_0_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
tiletamine-6013	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
AP3D1	Pathway Commons Protein-Protein Interactions	1.0	null
RS4-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-3.44652
GABPA_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_6008_KD_DDX17_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
CE-04-HT15_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.208637
GSE205163,GSE205164_1_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.331
BRD-K81418486_vorinostat_AGS_6.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
nordihydroguaiaretic acid-1164	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K69840642_HDAC6 inhibitor ISOX_VCAP_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7519
moroxydine-5304	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN010_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.55388
arcuate nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.2786
GTEX-WYJK-1026-SM-3NM8W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852263
BRD-A45498368_WYE-125132_MCF10A_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NELFE	ENCODE Transcription Factor Targets	1.0	null
BRD-A10420615_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EIF2D	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K39120595_BITHIONATE SODIUM_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CSNK2A2	Pathway Commons Protein-Protein Interactions	1.0	null
SP2	ENCODE Transcription Factor Targets	1.0	null
GSE242049_1_v_0_txndc5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-6546-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UMUC3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40951
Perturb_8634_KO_Htr6_SRP223109	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.91504
AB-18-YN11_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.806751
GSE148252_1_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K12502280_TG-101348_A549_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.37874
TE-32-AC63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.206307
GSE211262,GSE211263_3_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CB-24-FA25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.443576
KDM4A	ENCODE Transcription Factor Targets	1.0	null
transport	GO Biological Process Annotations 2015	1.0	null
RAB6A	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K86797399_pracinostat_HCC515_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MYO7B	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K41853443	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53691
r5 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11593
BRD-K09854848_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XOT4-0526-SM-4B66O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39565
BRD-A43331270_niguldipine hydrochloride_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN015_MCF10A.WT.HP_24H:M22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4928
BB-42-FF52_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.287411
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DB-21-FY25_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.239633
r6 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28579
GSE199606_2_v_7_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
XC-13-LW13_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.210861
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.072543
DD-73-IP88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.349012
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.1483
DRD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21461
BRD-K71778797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42926
GSE151494_1_v_9_nrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CA-16-ZL71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.444091
GSE151612_0_v_2_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-PAX6_UNIQUE_DYS_GENES-NEUN_TLE_vs_TL_log2FoldChange_1_padj_0_1_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
AKT1S1	Pathway Commons Protein-Protein Interactions	1.0	null
SWAP70	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K64890080_BI-2536_MCF10A_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
jm2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.911
GTEX-SNOS-0326-SM-4DM6C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31779
DD-47-GB64_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.39381
AE-04-SN76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.900663
GTEX-OXRL-0426-SM-3NM97	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897394
GTEX-PLZ4-0008-SM-48TE6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971277
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VJYA-0226-SM-4KL1Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15045
CRCGN015_MCF10A.WT.HP_24H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.33248
GSE48812_0_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
YY1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DIAPH1	Pathway Commons Protein-Protein Interactions	1.0	null
DHFR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99564
GATA1	ENCODE Transcription Factor Targets	1.0	null
BRD-U22633929_XMD11-85H_MCF10A_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PC-87-OG75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.428679
GTEX-U3ZM-0326-SM-4DXUJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09247
FC-85-OX77_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.46583
CD-16-KY17_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.278353
Necrosis	CTD Gene-Disease Associations	1.0	1.46436
GTEX-T6MN-2726-SM-4DM77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53375
CRCGN015_HEPG2_48H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.40497
BRD-K74211805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73941
FB-75-YG01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.210622
H3K79me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5468-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
496100576_HIP_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.38658
CRCGN013_HEPG2_24H:K03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.04147
GSE113734_3_v_0_qprt_human	RummaGEO Gene Perturbation Signatures	1.0	null
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MAPK1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K81418486_vorinostat_NCIH508_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GB-57-XV52_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.824599
BRD-K40175214_torin-1_MCF10A_3_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WL46-2926-SM-3LK82	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888791
SEPT9	Pathway Commons Protein-Protein Interactions	1.0	null
SE-81-RI20_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.297447
BRD-K18515345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71155
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.8567
MAP2K3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K45037973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64017
9653_USP37_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.04406
CRCGN017_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.22253
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17201
GTEX-WWYW-0526-SM-3NB2W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25094
BRD-K53414658_tivozanib_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PRKAG1	Pathway Commons Protein-Protein Interactions	1.0	null
meclofenoxate-4268	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE216273,GSE216292_0_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE205730,GSE205731_2_v_0_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A48570745_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-RTLS-1326-SM-46MUN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.20533
NCIH650	CCLE Cell Line Gene CNV Profiles	-1.0	-2.09288
KB-05-VJ83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.24698
BRD-K77535986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41199
BRD-K74892102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49004
BRD-K50133846	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.68414
GSE147876,GSE147877_4_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K81515704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19562
GSE211931_0_v_3_ncoa4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE128634,GSE128636_4_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
malignant	GeneRIF Biological Term Annotations	1.0	null
Facial motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62191
CRCGN011_HEPG2_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.71425
PMC10279693-41389_2023_477_MOESM2_ESM.xlsx-N_MYC-WDR5-DMSO-overlap_peaks_a-Unnamed_14_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
MYOF	Pathway Commons Protein-Protein Interactions	1.0	null
GSE171292_6_v_0_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-U64521890_XMD16-144_MCF10A_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cyproterone-6124	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
AA-22-UI44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.357972
BRD-K98276754	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8187
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RB1_KD_GSE50532_654_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
dorsolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07133
Squamous Cell Carcinoma Of Esophagus	DisGeNET Gene-Disease Associations	1.0	null
GSE222047_0_v_1_imidazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2AphosphoS5_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-NJ-A4YF-01A-12R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE116930,GSE116935_3_v_0_hes7_human	RummaGEO Gene Perturbation Signatures	1.0	null
DF-00-BU08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.218126
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA-60-LK14_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.255142
fulvestrant-6925	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN009_HEPG2_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9608
GSE191138_2_v_4_fmo3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CBX3_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PC-87-OG75_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.407087
BRD-K81418486_vorinostat_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2AphosphoS5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
liver	GTEx Tissue Gene Expression Profiles	-1.0	-1.33081
GSE48812_8_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CC-03-PW00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.459776
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.39132
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.88307
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
KE-91-GT92_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.273578
CAKI1	DepMap CRISPR Gene Dependency	1.0	2.27495
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
b-lymphocyte	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SE-81-RI20_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.244143
CB-82-PL01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.54556
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN013_HEPG2_24H:H20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1695
vitamin c_mus musculus_gpl1261_gse37676	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-S3XE-0326-SM-4AD6L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17513
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HUP-T4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16851
Perturb_8028_KO_IRTKS_SRP310479	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
COG4	Pathway Commons Protein-Protein Interactions	1.0	null
PMC9795333-mmc4.xlsx-HUES66_Ex_CTIP2_C3-X-linked_genes_BCL11B	Rummagene Transcription Factor Associations 2026	1.0	null
GABPA_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75729
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
thus	GeneRIF Biological Term Annotations	1.0	null
YY1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
solasodine-2170	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-520a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
BC-75-FA82_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.320747
hsa-miR-520b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GSE128730_3_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DAUDI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.866685
Fetal Brain Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.917684
r7 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.87857
BRD-K07624584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.39724
GTEX-OHPL-1026-SM-3MJGI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.957903
BRD-K82805160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.64908
DA-40-HO94_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.259589
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30099
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052105
HC-11-RK51_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.287514
GC-86-TD91_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.210215
USF1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE199255,GSE199356_6_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BE-38-UW72_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.429813
ACTN4	Pathway Commons Protein-Protein Interactions	1.0	null
AE-56-SL06_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.28283
NE-37-JX51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.224086
GD-79-TW34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.12843
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.94265
Omasum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.53
HCC1833_LUNG	CCLE Cell Line Proteomics	1.0	3.35195
GSE206516,GSE206518_3_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.WT.HP_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.96297
CE-72-GF32_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.293895
GSE130396_8_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SLC9A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04046
BRD-K66985689	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.33355
PMC7870953-41540_2021_169_MOESM9_ESM.xlsx-SALL2_targets-target_gene_SALL2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K81623965	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17274
GSE133516_0_v_3_kat7_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7884
BRD-K11457257	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89754
GLYR1	Pathway Commons Protein-Protein Interactions	1.0	null
sirolimus_homo sapiens_gpl2895_gse16944	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-let-7c-5p	MiRTarBase microRNA Targets	1.0	null
GSE130217_0_v_3_sesn2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LA-09-SS14_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.200824
GTEX-WYJK-1726-SM-3NM9U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18955
EIF4E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94369
VTI1A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE151494_1_v_4_nrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NFYB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K76907295_VU0418947-2_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-T5JC-2526-SM-4DM6G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08046
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GABPA_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
establishment of localization	GO Biological Process Annotations 2015	1.0	null
synaptic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.210894
possible	GeneRIF Biological Term Annotations	1.0	null
DDA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18172
CRCGN013_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.64632
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN013_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.97268
17906199-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
GTEX-SJXC-1226-SM-4DM78	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.62869
XB-70-NK42_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.229737
BRD-K63068307_ZSTK-474_MCF10A_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN008_HEPG2_24H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.56225
BRD-K38574421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50269
BRD-K52001024	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40318
BB-79-AG41_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.518676
GTEX-TKQ2-0426-SM-4DXUO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904404
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.912745
CB-06-FE89_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.23413
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K59957885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83922
FOXP2_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20944
pancreas	GTEx Tissue Gene Expression Profiles	-1.0	-0.999549
PPM1A	Pathway Commons Protein-Protein Interactions	1.0	null
NRAS	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K23467057	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12984
CRCGN014_HEPG2_24H:H21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.74532
peripheral nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.079463
AP2B1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE180277_0_v_1_bach2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A19037878_trichostatin A_CORL23_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12130484-12276_2025_1444_MOESM2_ESM.pdf-22-EBF4_EBF4	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_MCF10A.WT.HP_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.80382
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17073
OA-12-SU22_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.27214
FNBP1L	Pathway Commons Protein-Protein Interactions	1.0	null
putamen, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.851602
C1orf21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10572
Childhood Neuroblastoma	DisGeNET Gene-Disease Associations	1.0	null
GC-07-UO80_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.208276
MYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9181
CRCGN014_HEPG2_24H:O09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.54041
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OHPN-0008-SM-4E3HW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82535
GTEX-TKQ2-0826-SM-33HB6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70156
EPAS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.875
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
DF-32-EL16_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.264651
DA-58-LZ09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.627115
IB-33-TE51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.617357
GTEX-XYKS-1726-SM-4E3IO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51602
GSE193402_0_v_2_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HD-89-HC56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.202139
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ANO6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00581945
BRD-K49865102_PD-0325901_A375_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K67578145_GDC-0879_A375_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EA-93-KT88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.537644
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PA-57-FX61_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.202484
tanespimycin-1166	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
autonomic nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.287447
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.312
Brain Lower Grade Glioma_LGG_TCGA-QH-A65X-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE167886_2_v_1_chd7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cerebellar purkinje cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.478923
Lung squamous cell carcinoma_LUSC_TCGA-85-8070-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
7-aminocephalosporanic acid-4826	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
OE33_OESOPHAGUS	CCLE Cell Line Proteomics	1.0	6.65263
GSE242049_1_v_0_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SNAP23	Pathway Commons Protein-Protein Interactions	1.0	null
Squamous Cell Carcinoma Of Skin	DisGeNET Gene-Disease Associations	1.0	null
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059451
BRD-A19037878_trichostatin A_SNGM_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K89040444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.20687
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051574
ZE-45-CG69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.670317
BRD-K10010414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60166
amylocaine-4089	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
IB-30-KN41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.477063
RABL6	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN014_HEPG2_3H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.2265
NUP153	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67774
Brain Lower Grade Glioma_LGG_TCGA-DB-A75O-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFYB	ENCODE Transcription Factor Targets	1.0	null
GSE147210_3_v_5_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.920115
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE147876,GSE147877_2_v_6_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PD-70-VS77_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.998041
BRD-K95937143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15624
CRCGN009_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4242
CRCGN015_MCF10A.WT.HP_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.50835
RIF1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-S341-1826-SM-3K2AB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24064
GD-59-OG21_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.233926
primary auditory cortex (core)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.923348
Hypertrophy	CTD Gene-Disease Associations	1.0	1.17202
GTEX-T8EM-1326-SM-3DB7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.908559
nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.831099
Sertoli cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.912
BRD-K68174511_-666_PC3_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H4K5ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-QVJO-0526-SM-447CE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02307
KIF20B	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PA-40-NS72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.201071
AD-20-AA40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.390397
DA-35-DU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.25253
CRCGN015_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7354
Brain_Germinal_Matrix	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.924773
CBX3	ENCODE Transcription Factor Targets	1.0	null
GSE77108_4_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NB-12-ZK38_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.385425
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.590036
H3K36me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organelle membrane	GO Cellular Component Annotations 2015	1.0	null
CRCGN009_HEPG2_24H:G02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.26271
GTEX-RN64-1826-SM-48FDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.50789
BRD-K57343972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46962
GSE152432_9_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE184892_6_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01358
SNU489	CCLE Cell Line Gene Expression Profiles	1.0	1.6574
transmission	GeneRIF Biological Term Annotations	1.0	null
BRD-K08406395	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16797
496100440_FWM_possible Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.17469
VPS18	Pathway Commons Protein-Protein Interactions	1.0	null
GSE216274,GSE216292_4_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.29659
SMEK1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN017_MCF10A.WT.HP_24H:I01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0015
DE-52-BS63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.341909
neuroblastoma	GeneRIF Biological Term Annotations	1.0	null
Liver Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
BA-15-VE07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210872
GTEX-XPVG-2526-SM-4B66D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00403
ZKSCAN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7989
BRD-K81418486_vorinostat_HA1E_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NUP160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01656
BRD-K66207462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.38726
ergolgi	GeneRIF Biological Term Annotations	1.0	null
GTEX-QXCU-1726-SM-2TC6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.94903
metformin-61	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SRPRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22046
CRCGN015_MCF10A.TP53.M_24H:E11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23855
STX3	Pathway Commons Protein-Protein Interactions	1.0	null
amygdaloid complex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27534
CRCGN015_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.00567
Midbrain reticular nucleus, retrorubral area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07648
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
QB-72-LM87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.331408
IRAK4_knockout_41_GSE12124	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.13464
CRCGN015_MCF10A.TP53.M_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.03935
GTEX-SSA3-0002-SM-3P61R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.880111
GSK3B_knockdown_209_GSE35351	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.76189
XE-29-LT20_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.21233
GSE178255_5_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ND-39-PO34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.22837
colo829	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.101
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.6087
BDCA4+_DentriticCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.48963
CP-320650-01-3822	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K88742110_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DD-15-VH74_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.506534
PMC10592471-NIHMS1912771-supplement-4.xlsx-D-HEp3_UP_NR2F1_ind_UP-NR2F1_Ind_UP_NR2F1	Rummagene Transcription Factor Associations 2026	1.0	null
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
BRD-K64857848_XMD-885_HCC515_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KIF2A	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K76694128_DCC-2036_A375_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
r9 part of the lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5703
BRD-K58208155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64996
TC-95-IR96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.248212
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10453
GTEX-RNOR-1426-SM-48FDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60993
PMC7581777-41419_2020_3029_MOESM6_ESM.xlsx-MNX1_ChIP-Symbol_MNX1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RVPU-2426-SM-2XCAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20016
FLI1_01_16	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.46903
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_6070_KD_SFPQ_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE217685_0_v_1_ddx20_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-69-7760-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
BRD-K63921431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2322
GTEX-XUZC-1326-SM-4BRV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.971428
GTEX-QVUS-0008-SM-447AY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04655
mantle zone of r3BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02883
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K36me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.32582
biological_process	GO Biological Process Annotations 2015	1.0	null
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8175556-42003_2021_2140_MOESM6_ESM.txt--CEBPD_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
MAZ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	126.058
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KIF1A	Pathway Commons Protein-Protein Interactions	1.0	null
POR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65324
Lung adenocarcinoma_LUAD_TCGA-49-4512-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6715699-41467_2019_11785_MOESM4_ESM.xlsx-CSL_KD-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TPX2	Pathway Commons Protein-Protein Interactions	1.0	null
EHD4	Pathway Commons Protein-Protein Interactions	1.0	null
transport	GeneRIF Biological Term Annotations	1.0	null
Rumen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.984
BRD-K85402309_dovitinib_MCF10A_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MAPK8IP3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K06863921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4787
SP1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE155305_2_v_0_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE134375_4_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GA-04-SF76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.21568
dorsolateral prefrontal cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.826657
GSE186633_2_v_0_chd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:E04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.57453
CRCGN015_MCF10A_48H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.27652
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FF-86-NH56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.993249
BCCIP	Pathway Commons Protein-Protein Interactions	1.0	null
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.47795
PMC12178829-mmc4.xlsx-Sheet_4-MEG3-KD_Up-GeneName_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0506
DF-00-BX35_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.516524
14768006-SuppTable4	GeneSigDB Published Gene Signatures	1.0	null
GTEX-PW2O-1726-SM-2S1OO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70124
BRD-K89142472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69209
USF1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsf1_17216044_hela_lof_human_gpl571_gds1733	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.766806
A-375 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.897
PD-11-LM65_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.678212
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.918173
BRD-K18190982_COT-10b_AGS_6.0_h_44.4_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K56120807	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30014
outer plexiform zone in extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.47657
BRD-K01615696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7272
S0-EE-XMXE_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.7215
BRD-K09767767	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57586
QE-35-YE15_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.213262
BRD-K96144282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05819
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JK-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.TP53.M_24H:L21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9262
POLR2A_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOS	ENCODE Transcription Factor Targets	1.0	null
UTP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31829
BRD-K04238122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23816
CRCGN016_MCF10A.WT.HP_24H:E19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.40855
BRD-K36363294_I-BET151_HA1E_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cerebral lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE192771_2_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.3395
plicamycin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26171
Leber congenital amaurosis_Retina_GSE3249	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.65269
OB outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10976
ME-54-JY76_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.320387
TXLNA	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K51335814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24279
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
COPII-coated ER to Golgi transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.501
GTEX-UTHO-0726-SM-3GAEN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32232
GTEX-WHSE-0011-R2A-SM-3P5ZL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23449
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6221-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CB-32-EI69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.446121
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-608	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
BC-72-DZ30_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.213568
BF-29-LU75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.394498
BRD-K61182411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70765
Lung adenocarcinoma_LUAD_TCGA-55-8616-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16941
GSE90552_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.WT.HP_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.17209
Prostate adenocarcinoma_PRAD_TCGA-HC-7742-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPS6KA5	Pathway Commons Protein-Protein Interactions	1.0	null
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.40599
NCIH1703	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33163
BRD-K49328571_dasatinib_A375_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.846136
CB-36-QH71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.305048
BRD-K30677119_PP-30_A673_6.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K08715918	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9505
HSPA1B	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K85235446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.2468
G120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.20751
GNB1	Pathway Commons Protein-Protein Interactions	1.0	null
rostral migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.936522
BRD-K74305673_-666_SKB_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE169152_3_v_2_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
homatropine-1848	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ILKAP	Pathway Commons Protein-Protein Interactions	1.0	null
ED-71-GA72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.766654
BD-62-ZF67_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.444891
JD-10-HW02_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.39066
GSE125782_3_v_2_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K48207398	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02078
BRD-K25757432	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64678
HDAC1	ENCODE Transcription Factor Targets	1.0	null
EGI-1	GDSC Cell Line Gene Expression Profiles	-1.0	-2.04549
DOCK1	Pathway Commons Protein-Protein Interactions	1.0	null
FOXP3-21729870-TREG-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ROS50	DepMap CRISPR Gene Dependency	1.0	2.91759
CRCGN011_HEPG2_24H:A12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.68205
GSE160817_5_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
JA-82-EV20_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.249036
BRD-K54250149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06145
CTNNB1_Inactivation_GDS2984_628_mouse_Intestinal crypts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
jf1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.122
HT-3	GDSC Cell Line Gene Expression Profiles	-1.0	-3.21362
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02401
GSE164757,GSE164759_4_v_3_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.4122
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VASP	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H292	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.31924
CRCGN014_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.6715
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
HGS	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.34869
BB-10-PR06_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.375819
DF-84-RT50_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.221207
wt1_17420277_e11dot5_urogenital_ridge_lof_mouse_gpl1524_gds2747	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.032532
GSE168750_0_v_1_slc7a5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:H02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.1166
CRCGN017_MCF10A.TP53.M_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23921
CRCGN011_HEPG2_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9422
Lung squamous cell carcinoma_LUSC_TCGA-60-2708-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZN-2226-SM-3DB88	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3141
BA-84-TD72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.431473
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PITPNA	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45591
several	GeneRIF Biological Term Annotations	1.0	null
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02032
GTEX-PVOW-0126-SM-2XCFA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22372
BRD-K88677950_PD 198306_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K51898276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32169
GIGYF2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26122
GTEX-QEG5-1226-SM-447AR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28647
MED7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10769
BRD-K43271856	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89779
UE-90-AA63_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.203232
TAF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A24396574_celastrol_LNCAP_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE121866_0_v_3_six4_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K61027868	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35523
DA-10-HD17_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.785863
GSE142210_11_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
USF2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CNPY3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K01976263_Emetine Dihydrochloride Hydrate (74)_LOVO_6.0_h_0.63_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
USF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHB2	Pathway Commons Protein-Protein Interactions	1.0	null
cf2th	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.669
BRD-K09499853_KU 0060648 trihydrochloride_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TAF1_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EFO21	CCLE Cell Line Gene CNV Profiles	-1.0	-1.92894
VDR	ChEA Transcription Factor Targets	1.0	null
AA-23-FM46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.741745
endometrium	HPA Tissue Gene Expression Profiles	1.0	0.830848
GSE172295_3_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.7636
ETS1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7692-01A-12R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_3H:G02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.31442
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_4_Overlap_of_ERM_proteom-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
ML-1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.05631
AB-00-IL62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.460995
BRD-K17743125_belinostat_HA1E_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BE-82-TS38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.330917
BD-73-TX58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.516357
BRD-K68174511_torin-2_HEPG2_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE198165,GSE198166_6_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCM4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00475014
RA-49-ZB08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.41762
NCIH1651	CCLE Cell Line Gene CNV Profiles	1.0	2.59998
POU5F1	ChEA Transcription Factor Targets	1.0	null
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K62320774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07252
GF-35-IT27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.537996
SIX5_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BF-94-CQ58_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.20117
FF-90-JK74_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.13889
SIX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28929
BRD-K24859147_KIN001-242_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
IC-98-UO17_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.582184
AE-04-SN76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.709988
CRCGN014_HEPG2_3H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3885
BRD-K68853384	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65233
ticarcillin-6146	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
subgranular zone of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.849183
22RV1	DepMap CRISPR Gene Dependency	1.0	4.54107
smooth muscle	HPA Tissue Gene Expression Profiles	1.0	1.37555
B-lymphocyte cell line	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K24700188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.90709
OD-77-AG95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.206801
BRD-K84924563_6-diazo-5-oxo-l-norleucine_SKM1_6.0_h_40.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC11214527-mmc5.xlsx-TP53-gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K28036658	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60789
BRD-K13761649	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12203
triprolidine-7408	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
IE-38-FB31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.27796
BRD-K60337516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69666
GTEX-WFG8-0126-SM-4LVMH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23572
BRD-K79090631_CGP-60474_PC3_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K57080016_selumetinib_A375_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CEBPB_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Stat5a::Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.9227
REST_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K02301426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00127
Lung squamous cell carcinoma_LUSC_TCGA-NK-A5D1-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ME-73-FK70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.221769
benzbromarone-1291	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FA-80-DR66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.217525
RACK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92599
BRD-K82244940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69118
BRD-K64890080_BI-2536_MCF10A_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CA-60-LK14_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.377714
GTEX-X3Y1-0726-SM-3P5YU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4781
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34089
BRD-K06486611	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10762
BE-41-AV63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.352993
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G28T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.16615
BRD-K44227013_ponatinib_A375_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K70286959	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52861
18801183-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
BRD-A39996500_radicicol_MCF10A_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K04853698_LDN-193189_SKBR3_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE192689_0_v_1_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K36740062_GSK-1070916_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC9336541-Table_3.XLSX-C-vs-H6-L_filter_annot-Unnamed_18_HMX1	Rummagene Transcription Factor Associations 2026	1.0	null
BT549	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.37013
CRCGN009_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6508
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04328
CRCGN017_MCF10A.TP53.M_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8635
AD-21-WS76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.245246
BRD-K97348029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.38107
SARS-BatSRBD_84Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.15108
EA-93-KT88_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.750332
BRD-K32925057	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.10534
BRD-K07489055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14677
Lung squamous cell carcinoma_LUSC_TCGA-43-5668-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE174701_4_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5888-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K10638173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16626
GSE147056_0_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCFC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZH-3026-SM-3NB1G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963779
hsa-miR-4651	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
BRD-K99903568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30373
Lung squamous cell carcinoma_LUSC_TCGA-33-4582-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4872-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE223287,GSE223290_2_v_4_braf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EJ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ascl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.993
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_x_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K33503286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47743
BRD-K21680192_mitoxantrone_MCF10A_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
intermediate stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.14848
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36007
CRCGN010_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.8424
AF-80-GK24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.859939
GTEX-PWOO-0326-SM-48TDB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961124
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.827504
CTNNB1	Pathway Commons Protein-Protein Interactions	1.0	null
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059304
TXLNG	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K02802091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12057
GSE179880_1_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
internal segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.948922
BRD-K63606607_-666_SKB_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.391
Endoplasmic reticulum exit site	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.401
SARS-BatSRBD_72Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.45947
CRCGN010_HEPG2_24H:C17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5498
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:G12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.49168
CRCGN011_HEPG2_24H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.5515
GTEX-WFON-0326-SM-3GIKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.916176
BRD-K92571446_WZ-3105_A375_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-RY-A83Z-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K00337317_NU-7441_PC3_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN015_MCF10A.TP53.M_24H:M08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9182
praf2	GeneRIF Biological Term Annotations	1.0	null
TM9SF1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K51535480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0412
TA-19-YA45_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.488978
BRD-K05939258	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86949
BRD-K76521932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.3998
Thalamus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.14166
BRD-K49345010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56346
BRD-K68336408_Tyrphostin AG 1478_HCC515_24.0_h_56.78_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AB-09-EA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.01655
GTEX-P4PQ-1026-SM-3NMCN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23058
BRD-A25736793_everolimus_HCC515_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A46747628_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
AD-16-HL96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.20015
IF-31-RN78_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.12642
CRCGN017_MCF10A.WT.HP_24H:I16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7902
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.892221
BRD-K35848924	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07421
GTEX-R53T-1826-SM-3GIJX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33729
G protein-coupled receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.361
BRD-K17743125_belinostat_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN016_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.55434
BRD-K70642949_GSK-2334470_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-133a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
CRCGN012_HEPG2_24H:G19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.48402
POLR2AphosphoS5_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EW22	DepMap CRISPR Gene Dependency	1.0	2.05549
PTSD - Post-traumatic stress disorder_Peripheral blood mononuclear cell_GSE860	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.77309
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2726-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NB-24-VE53_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.243993
GSE195663_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K35724671	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58201
GTEX-OHPN-2826-SM-3LK67	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854474
GTEX-POYW-0526-SM-2XCEY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00752
GC-04-UF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.588122
CB-49-OG36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.429936
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19O-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CF-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF7L2_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4QT-0008-SM-48TDZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15374
GTEX-QLQ7-0008-SM-447AW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956838
GSE95077_1_v_0_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K36me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K86694287	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98105
GTEX-Q2AH-0326-SM-48U1K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0674
GSE122215,GSE122217_5_v_1_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K79090631_CGP-60474_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Primary somatosensory area, upper limb, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19266
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PK1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.67169
GTEX-POYW-1126-SM-48TCI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80314
BRD-K93123848_RAF 265_A375_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LA-42-ER00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.932136
DB-41-IH69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.236754
BRD-K36740062_GSK-1070916_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K36me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.56807
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
BRD-K02708799_GSK-1059615_HEPG2_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BD-49-MD69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.390044
DOCK6	Pathway Commons Protein-Protein Interactions	1.0	null
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.16851
C-33-A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
17823660-TableS1a	GeneSigDB Published Gene Signatures	1.0	null
MAX_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7304-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MEF2A_MEF2A	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVN-0426-SM-48TZ6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21854
SCAF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09071
limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me1_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
LUDLU1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34075
STX5	Pathway Commons Protein-Protein Interactions	1.0	null
PC-44-DH10_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.229464
BRD-K20355073	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05817
BE-47-IP08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.226574
RB-34-TO07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.218039
BRD-K51849151	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7446
PMC6604319-13072_2019_278_MOESM3_ESM.xlsx-CEM_ect_TET2_DEGs_DMRs_hDMRs-CCRF-CEM_EV_vs_ectopic_TET2_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
HCC2279	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52492
GSE210885_2_v_1_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CHMP5	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K11414036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50545
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K68007270_-666_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.13468
BRD-K03122949_5102-0187_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
STAMBPL1	Pathway Commons Protein-Protein Interactions	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-YA-A8S7-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ILK_activemutant_78_GSE25729	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.62334
GSE163297_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.4031
GTEX-PVOW-2726-SM-48TCA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956637
BRD-K36363294_I-BET151_A549_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RAB17	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K01436366_XMD-1150_BT20_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K16485616_mocetinostat_HCC515_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.24479
PC14	CCLE Cell Line Gene CNV Profiles	-1.0	-1.86433
ion transport	GO Biological Process Annotations 2015	1.0	null
SETD1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00419032
GSE205976,GSE205978_2_v_5_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
articaine-6517	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Dehydration_Hypothalamus_GSE3110	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	4.03003
EF-74-KW12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.33287
CRCGN016_MCF10A.WT.HP_24H:A19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.11803
GTEX-RUSQ-0426-SM-47JWR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906407
GTEX-XUW1-1726-SM-4BOOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885911
TCF12	ENCODE Transcription Factor Targets	1.0	null
CENPV	Pathway Commons Protein-Protein Interactions	1.0	null
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05817
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5010-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EBC1_LUNG	CCLE Cell Line Proteomics	1.0	2.72738
COL5A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21359
GTEX-SNMC-1326-SM-2XCFK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.975774
lateral part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.84906
EA-92-CV45_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.203265
retroparafascicular area of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.41209
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CA-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE205163,GSE205164_5_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE180951_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K72933250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59992
BRD-K00337317_NU-7441_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A19037878_trichostatin A_HEC108_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TT-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K03063480_PF-477736_MCF10A_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F4	ENCODE Transcription Factor Targets	1.0	null
BRD-K05154886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45842
GSE164874_5_v_6_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
ERGIC1	Pathway Commons Protein-Protein Interactions	1.0	null
lysergol-1325	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.37165
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.77133
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01444
DBTRG05MG	CCLE Cell Line Gene Expression Profiles	1.0	1.46059
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.913503
BRD-K49328571_dasatinib_A375_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
OVCA 429	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06613
GSE167886_2_v_0_chd7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:F11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3507
H3K36me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bounding membrane of organelle	GO Cellular Component Annotations 2015	1.0	null
BRD-K78574327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74056
NB17	DepMap CRISPR Gene Dependency	1.0	2.76229
CAMA1	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.655948
GSE174701_5_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE201657_0_v_1_ash2l_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE186440,GSE186443_2_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08606
KP4	CCLE Cell Line Gene CNV Profiles	1.0	1.33595
loperamide-5632	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HF-91-IU60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.304912
GSE216043_10_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE206400_1_v_2_nusinersen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTF3C3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38136
mantle zone of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.85743
BRD-K86899078_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE111247_2_v_8_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PML_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-O1-A52J-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE236262_0_v_3_trim28_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CLTC	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K02708799_GSK-1059615_HCC515_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BC-75-FA82_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.254823
ATP6V1H	Pathway Commons Protein-Protein Interactions	1.0	null
BA-90-AA10_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.249124
DF-45-GA42_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.288357
hMPV_48Hour_18234263_GSE8961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.261
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K83012560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45932
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28366
GSE122215,GSE122217_5_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-N7MS-0011-R2a-SM-2HML6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21744
PLEK2	Pathway Commons Protein-Protein Interactions	1.0	null
pipemidic acid-3093	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN009_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.05715
BRD-K21025364_NVP-TAE226_A375_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
vesicular	GeneRIF Biological Term Annotations	1.0	null
CTCF_HEK293_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10933434-44319_2024_69_MOESM2_ESM.xls-HRV16-UV_vs_MI-Ensembl_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
JB-28-VO37_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.203106
GTEX-RNOR-2426-SM-48FDY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16341
hsa-miR-875-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.957768
POLR2AphosphoS2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K34414758	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00189
GAMG	GDSC Cell Line Gene Expression Profiles	1.0	1.43007
BRD-K54606188_(+)-JQ1_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RRAS2	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN017_MCF10A.WT.HP_24H:L20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5635
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K94145457	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81651
GSE193258,GSE193259_5_v_15_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
kawain-2337	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EE-03-SG02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.461644
BRD-K05804044_AZ-628_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K62017257	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23796
CRCGN014_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.60857
CRCGN017_MCF10A.WT.HP_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22865
CRCGN012_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.23345
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RNF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2399
HD-99-BT62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.552471
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10679653-mmc3.xlsx-ISL1_KO_Markers-Unnamed_0_ISL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE174735_1_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JB-75-NC66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.209841
mantle zone of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51025
GTEX-S4Z8-0626-SM-4AD6J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967994
BRD-K99582188_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72975
BRD-K49075727_nintedanib_MCF10A_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_15827_OE_Nrf2_SRP291724	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	16.4159
BRD-K88510285_B675700.cdx_A375_24.0_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
r2 part of the trigeminal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15499
ALDH3A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00762642
SDHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01162
GSE218819_3_v_4_kdm5b_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K85110576	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.25422
S0-EE-XMWH_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.370678
BRD-K29039402	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3029
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
JD-62-TK68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.471747
GSE152432_5_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
ATM	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K93040255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13445
BA-52-FW03_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.30429
CPI-203	DeepCoverMOA Drug Mechanisms of Action	1.0	0.83
HC-86-IA49_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.208537
maturation	GeneRIF Biological Term Annotations	1.0	null
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in rostral cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.825759
SIN3A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44549
USF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE235550_1_v_0_hspa9_human	RummaGEO Gene Perturbation Signatures	1.0	null
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.826716
RAB5A	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K36575696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64878
BRD-K75081836_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN016_MCF10A.WT.HP_24H:B22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02862
BRD-K06792661_Narciclasine_SNUC5_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-UJMC-1826-SM-3GADT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67435
BRD-K68174511_torin-2_PC3_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A26002865_V4877_ASC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:F04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18396
GTEX-XUJ4-2626-SM-4BOQ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.976356
Squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.268
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.568109
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_5_TbID_-biotin_ERM_proteo-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.69384
GSE217452_3_v_1_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
OVCAR-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15845
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A459-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GAS2L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0542
BRD-K15609977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17437
CRCGN009_HEPG2_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.30597
cerebral cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15102
octopamine-6491	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.30381
BRD-K23782109	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09606
NG-108-15 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.619
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K45013233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01748
primary motor cortex (area M1, area 4)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.863113
orbital frontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03264
BRD-K01754917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05607
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNF8	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-A48237631_MITOMYCIN C_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-P4QT-0126-SM-2I3FL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.918138
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.920115
valproic acid_homo sapiens_gpl6883_gse26940	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K49075727_nintedanib_SKBR3_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE196505,GSE196507_3_v_2_kdm2b_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K02240568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64016
AA-80-XK94_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.289185
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.330379
GTEX-O5YT-1326-SM-3MJGR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889106
GE-77-FY84_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215024
BRD-K06926365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07618
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.4275
GSE199255,GSE199356_3_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
5-lipoxygenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.585
PACADD188	DepMap CRISPR Gene Dependency	1.0	5.6101
MNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0159
tubocurarine chloride-6351	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ARL1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN014_HEPG2_3H:A19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.70052
FRMPD3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K16715205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05225
BRD-A19037878_trichostatin A_VCAP_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Primary somatosensory area, upper limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64309
FC-20-EQ58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.824999
COG3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-A94756469_-666_ASC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K09499853_KU 0060648 trihydrochloride_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
moracizine-2959	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.89728
H4K20me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GRB2	Pathway Commons Protein-Protein Interactions	1.0	null
CC-88-JZ09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.205046
CHPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66412
H3K27ac_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.6374
GTEX-SSA3-0326-SM-32QPS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68253
FC-15-XG61_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.230982
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ANXA1	Pathway Commons Protein-Protein Interactions	1.0	null
KLF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.2212
basal ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.71328
survival	GeneRIF Biological Term Annotations	1.0	null
KLF4-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE120413,GSE120447_4_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K69453266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65316
KB-05-VJ83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.380622
KMOE-2	GDSC Cell Line Gene Expression Profiles	-1.0	-2.21167
GSE175787_13_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE96777,GSE96778_1_v_0_zbtb4_human	RummaGEO Gene Perturbation Signatures	1.0	null
FE-10-KQ78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.504639
BRD-K17175263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58793
Brain - Cerebellar Hemisphere	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.18376
GSE146982_3_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BD-04-NG34_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.222198
BRD-A68930007_-666_ASC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
estradiol_homo sapiens_gpl570_gse16683	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN011_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.22195
GTEX-WY7C-2526-SM-3NB2N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888923
PA-15-CP52_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.37999
PMC3964217-oncotarget-05-417-s001.xls-Supplemental_Table_2-ETS1-bound_promoters_ETS1	Rummagene Transcription Factor Associations 2026	1.0	null
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K23728544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40615
CRCGN016_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.08825
FAM131B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25533
BE-38-UW72_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.465719
PMC7098486-mmc2.xlsx-Kgg_Quant_NGN2_AAVS_-_WCL-Unnamed_2_NEUROG2	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2214
BRD-K90806964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11023
Periventricular hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.49959
GSS	CCLE Cell Line Gene Expression Profiles	-1.0	-1.55854
GTEX-XMK1-0326-SM-4B652	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13263
CTCF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K31363949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0125
hsa-miR-4693-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2227	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.60986
COLO 800	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39802
LAMTOR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07088
GTEX-S3XE-0526-SM-4AD4G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13972
BRD-K40558736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29822
BRD-K34192219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41018
GSE217071_3_v_0_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN014_HEPG2_3H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.4339
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE238116_1_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K26217579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03283
r7 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.51062
CRCGN017_MCF10A.WT.HP_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.27348
BRD-K42918627_GSK-2126458_A549_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K91671568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07877
BB-20-UU03_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.476844
BRD-K50278697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21296
TP53BP2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE101527_0_v_1_smad4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
YPEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1735
EPS8	Pathway Commons Protein-Protein Interactions	1.0	null
GSE124097_3_v_0_trem2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CA-42-YI34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.23517
GLIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.9301
HB-06-WU12_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.15447
GTEX-W5WG-1626-SM-4LMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08848
GTEX-WFG7-2226-SM-3GIKP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.966289
OE-18-ZX28_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.502908
CRCGN016_MCF10A.WT.HP_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.1876
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07601
GSE167474_2_v_3_naa40_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WFG8-2426-SM-3GILL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.33233
BRD-K91271834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21639
USF1_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
QE-00-EB96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.486204
BRD-K20285085_fostamatinib_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DA-35-DU85_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.449024
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE96641_3_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE102505_1_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.57254
ventromedial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.03793
EP300_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsal subdivision of VLC	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.888226
SIX5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PA-15-CP52_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.477571
EA-61-RR63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.35224
OE-18-ZX28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.560177
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.09925
BRD-K64606589_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
H3K36me3_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEL4-0008-SM-447AZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901649
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K38118311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39045
GB-73-QS80_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.24709
CRCGN016_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.7381
SAMD4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68343
DA-09-XJ53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.213023
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MB-49-LL22_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.270101
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
Parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.13851
HCC15_LUNG	CCLE Cell Line Proteomics	1.0	2.49059
WC-59-RG09_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.336458
BRD-K06792661_Narciclasine_TYKNU_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
intermediate stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52884
CRCGN014_HEPG2_24H:B07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.59659
GSE133070_2_v_4_prss1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WOFM-1326-SM-3MJFR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.861558
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21022
BRD-K54606188_(+)-JQ1_HCC515_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_6082_KD_TRA2B_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
amitriptyline-1701	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE242647_2_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
COPI-coated vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.119
BMAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28901
ARHGAP8	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-302e	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YE-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE152441,GSE152442_7_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE232631_4_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K07023879_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-7023-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE152432_3_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CA-68-KG29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.639836
TA-34-CK62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.213089
PMC11530610-mmc3.xlsx-WGCNA-TFAP2C_TFAP2C	Rummagene Transcription Factor Associations 2026	1.0	null
HCC2429	DepMap CRISPR Gene Dependency	1.0	3.41452
JHH2	CCLE Cell Line Gene CNV Profiles	-1.0	-2.3514
XPO4	Pathway Commons Protein-Protein Interactions	1.0	null
GABPA_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CTCF_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBK-0425-SM-3LK5O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47364
GSE120612_6_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CB-73-HZ47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.202146
496100626_FWM_no dementia_TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.19462
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4696-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DD-71-LY65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.297271
SP1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB157	CCLE Cell Line Gene Expression Profiles	1.0	1.3894
GTEX-S32W-1426-SM-4AD66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.384
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.32186
BRD-K88573743_A443654_HEPG2_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K47165178	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78292
YY1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
estradiol-1021	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K76618080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34014
CTCF_MCF-7_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TML8-1326-SM-4DXTO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55889
BRD-K10385824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88478
Adipose - Visceral (Omentum)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.67534
KDM5B	ENCODE Transcription Factor Targets	1.0	null
BRD-K81418486_vorinostat_VCAP_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K68174511_torin-2_HEPG2_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_6096_KD_ZNF326_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BRD-A70649075_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JN-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r3 part of the trigeminal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30794
organic anion transport	GO Biological Process Annotations 2015	1.0	null
IC-98-UO17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.430141
IC-80-CT90_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.322937
RAB23	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN014_HEPG2_3H:H18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.39403
JAK1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CPHXL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03907
EBF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92505
SEPT8	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K43620258_3,5-dichloro-2-hydroxy-N-(2-methoxy-5-phenylphenyl)benzenesulfonamide_PC3_24.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K67578145_GDC-0879_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K69840642_HDAC6 inhibitor ISOX_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K81418486_vorinostat_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC9170863__F4	PFOCR Pathway Figure Associations 2024	1.0	null
SCAMP1	Pathway Commons Protein-Protein Interactions	1.0	null
CAL-12T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15786
GTEX-OHPK-0326-SM-2HMJO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.919481
ventrolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.934086
BRD-K95768123	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.52995
REST_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
L-alpha-amino acid transmembrane transport	GO Biological Process Annotations 2025	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YK-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EB-67-WB79_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.390118
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.988414
ASCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07607
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.58262
BRD-A26002865_V4877_SKB_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DCAF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25104
BB-42-FF52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.388601
CRCGN013_HEPG2_24H:P01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.63556
PMC11686977-12967_2024_5960_MOESM9_ESM.xlsx-Sheet1-Supplementary_Table_4_The_co-precipitated_proteins_of_the_four_RORA_promoter_probes_P1_P2_P3_and_P4_and_beads_RORA	Rummagene Transcription Factor Associations 2026	1.0	null
S0-EE-XMXE_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.571485
layer 2 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34354
GTEX-SNOS-1526-SM-32PLW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00178
RBL1_KO_GDS1931_740_mouse_Neurospheres (MG-430A)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
RACGAP1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN008_HEPG2_24H:O18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.50755
CRCGN017_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	10.0
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01873
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCIH2887	DepMap CRISPR Gene Dependency	1.0	2.45989
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K06750613_-666_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_4581_KO_Carm1_SRP135904	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.34295
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.912745
CRCGN015_MCF10A.TP53.M_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.06955
GTEX-U3ZN-1426-SM-3DB87	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.83265
IB-30-KN41_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.237101
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3496
AF-42-MP86_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.223172
PMC5578490-pgen.1006879.s017.xlsx-Top_ETV1_downregulated_genes-Gene_Symbol_ETV1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K99638698	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06987
RAB35	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A624-01A-22R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
5162773-892	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
VPS28	Pathway Commons Protein-Protein Interactions	1.0	null
SQ1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54109
Flocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47299
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213650_3_v_2_everolimus_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NANOG-16518401-CHIP-PET-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K99728124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.22192
ventral tegmental area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.85435
BRD-K76694128_DCC-2036_A375_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BCLAF1	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-4725-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
BRD-K03406345_5-azacytidine_PC3_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BE-79-QU25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.449495
core of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41071
granular layer of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09906
GSE148252_7_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147876,GSE147877_2_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
flavoxate-2373	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-373	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
cerebellum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.852616
FC-85-OX77_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.416273
estradiol-1182	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ARL6IP1	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS5_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0093
BRD-A46747628_-666_ASC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KLC4	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K51275565	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21503
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE160817_4_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE81193_3_v_2_irf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K30172718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36349
PMC9601604-NIHMS1841143-supplement-SuppTable-2.xlsx-FOXO3-specific_targets-FOXO3-specific_targets_1218_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
dorsalrootganglion	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.04122
BRD-A94377914_-666_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SKP1	Pathway Commons Protein-Protein Interactions	1.0	null
DC-70-EK34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.22798
OSBP	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15303
BRD-K23478508_-666_ASC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K34581968_BMS-536924_A375_24.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
candidate	GeneRIF Biological Term Annotations	1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
inferolateral temporal cortex (area TEv, area 20)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05334
(-)-atenolol-3067	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-N7MS-1626-SM-3LK5F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.89567
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21106
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CDK1	Pathway Commons Protein-Protein Interactions	1.0	null
S0-EE-Y4UM_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.379303
RAD23A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07182
morantel-7250	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LB-11-CG51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.355538
BRD-K74761218_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
UE-90-AA63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.238979
GSE65617_0_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TNFAIP8	Pathway Commons Protein-Protein Interactions	1.0	null
GSE169152_3_v_4_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Fetal_Intestine_Small	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.44704
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01873
A-431 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.313
BRD-K73452131	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03132
Prostate adenocarcinoma_PRAD_TCGA-G9-6362-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LASP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02908
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Lung adenocarcinoma_LUAD_TCGA-64-1681-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW 982	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.888209
BRD-K49662642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12898
CRCGN016_MCF10A.TP53.M_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.49621
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.98563
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5191-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
phenformin-21	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SNB75	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.03025
MYH9	Pathway Commons Protein-Protein Interactions	1.0	null
ATF3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RALB	Pathway Commons Protein-Protein Interactions	1.0	null
SHSYSY-RA	BioGPS Cell Line Gene Expression Profiles	1.0	2.40167
RPMI-8226	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-1.95161
cell part	GO Cellular Component Annotations 2015	1.0	null
CF-65-GU65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.757222
GTEX-POMQ-1226-SM-3P61F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43672
FF-54-JC89_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.37736
osteoblasts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.29484
USF2	ENCODE Transcription Factor Targets	1.0	null
III, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.55228
BRD-K71755056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23744
CRCGN013_HEPG2_24H:K04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.91432
Psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41N-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SEC61A1	Pathway Commons Protein-Protein Interactions	1.0	null
CHP1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN012_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.03723
BRD-K62497619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25343
amygdaloid complex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.883296
GSE111247_2_v_7_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN012_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.94515
Aerial part	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.883
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.78489
BRD-K12867546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75308
H3K27ac_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.938957
superficial stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5703
SK-N-SH cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.884
GTEX-TML8-1826-SM-32QOR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1759
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.49798
GSE246195,GSE246305_1_v_0_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ability	GeneRIF Biological Term Annotations	1.0	null
CRCGN014_HEPG2_24H:J18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.3322
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Mel501 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.626
AE-13-CX28_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208343
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KJ-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
brain stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.073928
BRD-K89820077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7384
diphenhydramine-7318	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
XD-44-FJ34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.363944
Diabetic Nephropathy_Renal Tissue_GSE1009	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	0.402102
OC-71-BZ81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.338352
BRD-K01436366_XMD-1150_LNCAP_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN014_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.18214
BRD-K95871937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05973
VF-06-RV33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.532866
RRM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2073
ARHGEF10L	Pathway Commons Protein-Protein Interactions	1.0	null
GSE200839,GSE233826_3_v_6_tnrc18_human	RummaGEO Gene Perturbation Signatures	1.0	null
Magnocellular reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1095
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.906181
STX17	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-TMMY-1026-SM-4DXTI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827761
GSE185944_5_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K42475945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03647
PTPN1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K01467488	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07734
TC-95-IR96_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.382735
POLR2A_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBK-0526-SM-2HMJJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922574
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EIF2B1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE207863_0_v_1_hdac5_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7870953-41540_2021_169_MOESM9_ESM.xlsx-KLF5_targets-target_gene_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14109
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.53916
EXOC8	Pathway Commons Protein-Protein Interactions	1.0	null
GSE238116_1_v_0_egr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K21025364_NVP-TAE226_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K76899562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0384
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.912745
BRD-K15647573	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43596
periventricular stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42699
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE226114,GSE226116_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K65182930_NVP-AUY922_HT29_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMC1A	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-A45889380_QUINACRINE HYDROCHLORIDE_NCIH1836_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K9me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVUS-0426-SM-48FE3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38543
BRD-K38081867	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21507
CRCGN013_HEPG2_24H:J19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00146
layer 1 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12518
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
GSE146982_7_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K54606188_(+)-JQ1_HCC515_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung adenocarcinoma_LUAD_TCGA-95-7948-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2D	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00702296
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.1403
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Foxo3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.5348
CB-73-HZ47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.293248
GSE44157,GSE44163_1_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-5819-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_8587_KO_Adnp_SRP063269	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.34041
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.0167
Perturb_18103_KO_Parkin_SRP065536	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.60406
BRD-K31336762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68697
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213588_10_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
D-423MG	GDSC Cell Line Gene Expression Profiles	1.0	1.49241
UF-27-HS98_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.953403
BRD-K60437668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62767
intervention	GeneRIF Biological Term Annotations	1.0	null
PMC8405683-41419_2021_4120_MOESM2_ESM.xlsx-Sheet1-Table_S2_MYCN-responsive_gene_list_1_5_fold_p_0_05_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EC-60-IX15_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.406343
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A4JJ-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNX2	Pathway Commons Protein-Protein Interactions	1.0	null
ERMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48674
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K57080016_-666_A375_24.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Arrhythmogenic Right Ventricular Cardiomyopathy_Myocardial tissue_GSE4120	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.53466
PLEKHF2	Pathway Commons Protein-Protein Interactions	1.0	null
PBX3	ENCODE Transcription Factor Targets	1.0	null
NU-DUL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.64252
BRD-K74285424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0028
VF-06-RV33_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.312343
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
LD-69-ZV56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.35381
CRCGN009_HEPG2_24H:J03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.13779
brain ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.240826
H3K36me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenomedullin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.862
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K00337317_NU-7441_MCF10A_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03509
benserazide-5322	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K9me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NC-76-YX69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.277532
BRD-K64958595	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29114
CRCGN010_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.31735
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K68202742_trichostatin A_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057705
BRD-K81575721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.50844
GSE205976,GSE205978_2_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
XD-03-FM54_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.361369
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K92712225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50042
GTEX-S4P3-0626-SM-4AD59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.961471
DB-41-IH69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.300851
BRD-K81418486_vorinostat_CORL23_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-NPJ7-0011-R8a-SM-2I3G2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57008
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GSE133516_0_v_1_kat7_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_14107_KO_Setd2_SRP220107	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.35034
HE-10-QN66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.244857
GTEX-XPVG-1826-SM-4B64X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.998042
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.830612
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.263485
BRD-K79202867	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54962
CC-03-PW00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.312815
S0-EE-XMXE_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.483171
MB-49-LL22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.278714
BRD-K69932463_AZD-8055_MCF10A_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DB-21-FY75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.390962
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5EA-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCFC1_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.96387
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RNASE7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0054
GTEX-WHSE-0011-R8A-SM-3P5Z1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26708
HDQ-P1	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.93416
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.98677
BRD-K24124047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12375
hsa-miR-4492	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
MAFK	ENCODE Transcription Factor Targets	1.0	null
BRD-K76674262_-666_ASC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
GSE169152_3_v_7_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NA-30-HS87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.368433
GSE240896,GSE240899_3_v_0_ccnt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HEY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56754
BAZ1B	Pathway Commons Protein-Protein Interactions	1.0	null
CE-37-XI06_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.295615
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
OB olfactory fiber layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.32392
EGR1	ENCODE Transcription Factor Targets	1.0	null
amygdaloid complex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.841502
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-WT1_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
SETDB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DD-43-WW40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.433427
OCT4-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HD-99-BT62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.822941
Lung squamous cell carcinoma_LUSC_TCGA-60-2720-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DGKK	Pathway Commons Protein-Protein Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A194-01A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mitochondrion	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3141	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ECSIT	Pathway Commons Protein-Protein Interactions	1.0	null
pyramidal layer of IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01211
BRD-K13049116_BMS-754807_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-3187-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3M9-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPL-0008-SM-4E3I9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89519
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
superficial stratum of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01211
Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J7-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS819T	CCLE Cell Line Gene Expression Profiles	1.0	1.4422
CD-41-RE87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.490512
HE-84-SC79_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.210107
Prostate adenocarcinoma_PRAD_TCGA-HC-A4ZV-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BT-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area, lower limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01606
BRD-K67506692_EI-263_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ELK4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6128
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21903
membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.203361
breast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.225395
MYC-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-REY6-1226-SM-48FDR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48748
RMUGS	DepMap CRISPR Gene Dependency	1.0	4.47935
CRCGN014_HEPG2_24H:H13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.93909
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3335-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.06044
RALA	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-326	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
colorectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.251279
BRD-A58803929	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14669
BRD-K04408214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12573
GSE198165,GSE198166_0_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HD-51-KD29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.322321
CRCGN016_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.76098
BRD-K51185182	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17729
GSE193258,GSE193259_5_v_1_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27129
TCF12_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
DOR 13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.877578
PMC3966871__F3	PFOCR Pathway Figure Associations 2023	1.0	null
BRD-K10505056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.11356
QE-18-WG07_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.573835
BRD-K50689779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18537
USF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A700-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AD-52-UZ45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.208989
GTEX-XGQ4-0226-SM-4GIDS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.861967
GSE210580_4_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-8547-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZN-0726-SM-4DXT5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905401
TJP1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K68336408_Tyrphostin AG 1478_MCF7_24.0_h_56.78_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE147959,GSE147960_5_v_3_stat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	10.0
BRD-A25736793_everolimus_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN016_MCF10A.TP53.M_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.25951
ZBTB24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.6969
GTEX-XBED-1526-SM-4AT5W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.867788
SA-63-NG30_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.334015
BRD-K67979704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05022
ZC-12-OO11_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.2333
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FV-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.TP53.M_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.64023
CRCGN017_MCF10A.WT.HP_24H:J07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30245
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EA-32-CY22_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.230379
CRCGN013_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.88439
BRD-A68797623	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35261
CRCGN014_HEPG2_3H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.07927
XC-13-LW13_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.295363
LOU-NH91	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.86429
Superior olivary complex, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34627
BRD-A75409952_wortmannin_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC11465086-mmc2.xlsx-Table_ES_1_markers_c0_LPS_Vs_Co-Gene_Expression_Data_1_markers_c0_LPS_Vs_Control_related_to_Figure_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K42918627_GSK-2126458_A549_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HC-86-IA49_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.281761
CRCGN013_HEPG2_24H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.73239
BRD-K92212152	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53296
AA-23-FM46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.22468
GSE88819_7_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
XPO7	Pathway Commons Protein-Protein Interactions	1.0	null
HCC827	CCLE Cell Line Gene Expression Profiles	-1.0	-1.70076
SAP30	ENCODE Transcription Factor Targets	1.0	null
DA-10-HD17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.273179
SEC61B	Pathway Commons Protein-Protein Interactions	1.0	null
NCAPG	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K81954791	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56945
BRD-K77797589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0475
PC-80-LV29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.268507
cefixime-1310	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BCL6-25482012-CML-JURL-MK1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MAPKAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40465
BRD-K23430405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46423
ETS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12814
GSE93309_2_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158197_0_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cytoplasmic membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.205399
AA-91-WB95_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.230453
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
myosmine-4293	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Tumor Cell Invasion	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-OIZI-1426-SM-3NB1T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846616
BRD-K12502280_TG-101348_MCF10A_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LA-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.627972
SNU520	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58538
BRD-K25718133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44428
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN009_HEPG2_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.20831
NRF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-7631-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K68174511_torin-2_PC3_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GOSR2	Pathway Commons Protein-Protein Interactions	1.0	null
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.24657
GSE195786_0_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08972
AE-56-SL06_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.309958
BRD-K66823946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48153
FB-24-UT80_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.3764
BRD-K86574132_-666_MCF7_24.0_h_48.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
liver	HPA Tissue Gene Expression Profiles	-1.0	-0.901213
PSEN1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K62150807	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23857
BRD-K76450502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10193
intermediate stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36507
BRD-K21680192_mitoxantrone_MCF10A_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.14374
GSE199660_1_v_3_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FUOM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40925
HCC2157	CCLE Cell Line Gene CNV Profiles	1.0	1.81
Asarone	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.26
GSE147876,GSE147877_4_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SETDB1	ENCODE Transcription Factor Targets	1.0	null
STEAP3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K85402309_dovitinib_PC3_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE213588_9_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PC-87-OG75_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.247619
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.51595
BRD-K82539366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10023
MDA-MB-157	GDSC Cell Line Gene Expression Profiles	1.0	1.64291
DVL3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00365496
POLR2AphosphoS5_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
l-glutamate transport	GO Biological Process Annotations 2015	1.0	null
GSE145311_1_v_3_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE97352_3_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE171292_5_v_2_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.39787
NR0B1-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
FLCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03143
GSE179002_3_v_1_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE261563_3_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TTF2	ChEA Transcription Factor Targets	1.0	null
GSE82032_3_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K38417094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59331
GTEX-WZTO-0011-R4A-SM-3NMC7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961219
SEC22B	Pathway Commons Protein-Protein Interactions	1.0	null
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0786
CRCGN017_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.889
CRCGN017_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.57269
BRD-K21025364_NVP-TAE226_A375_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
forebrain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE134375_0_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08632
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.464
dorsolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.905534
BRD-K23197669	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85622
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052206
GTEX-OIZG-0008-SM-4E3J2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06423
IV, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.5886
RA-42-CM42_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.261806
GTEX-PVOW-0426-SM-2XCF8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65136
BRD-U22633929_XMD11-85H_BT20_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-182	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
CRCGN015_HEPG2_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	10.0
RAB9A	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-A17831693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.76086
RPS27A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0070348
CRCGN016_MCF10A.TP53.M_24H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.07855
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.945631
posterolateral cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07246
BRD-K08219523_5-nonyloxytryptamine_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K06792661_Narciclasine_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
UHMK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22848
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PW2O-0008-SM-48TEB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08477
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT5A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
COR-L311	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.93416
BRD-K91469267	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55939
Perturb_5795_KO_Stat3_ERP105170	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.7451
GTEX-OHPL-0426-SM-3TW8X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63372
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05164
BRD-K50157358	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11691
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A4AV-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE152055_0_v_1_mpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K68174511_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-U3ZN-0226-SM-3DB8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84869
GSE178227_1_v_0_tet1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
heptaminol-6015	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
AGI-6780	DeepCoverMOA Drug Mechanisms of Action	1.0	0.32
BRD-K86797399_pracinostat_A549_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TLN1	Pathway Commons Protein-Protein Interactions	1.0	null
ARL6IP5	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN015_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.87163
BRD-K20285085_R406_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
STAT5A	ENCODE Transcription Factor Targets	1.0	null
CRCGN017_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.78235
SNX12	Pathway Commons Protein-Protein Interactions	1.0	null
SHSYSY+RA	BioGPS Cell Line Gene Expression Profiles	1.0	1.44404
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.71692
CRCGN017_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.99811
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.18022
inferior nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.888553
SW 780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.931116
DD-55-AU25_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.243535
BRD-K06792661_Narciclasine_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K59317601_INK-128_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE86507,GSE86509_7_v_8_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XV7Q-1626-SM-4BRWC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48317
SIN3A	ENCODE Transcription Factor Targets	1.0	null
BRD-K79090631_CGP-60474_HCC515_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K45042519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30334
GSE247764_4_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:D02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.03723
TOV112D	DepMap CRISPR Gene Dependency	1.0	2.48864
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K81418486_vorinostat_HCT116_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-QEL4-1326-SM-447AD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22204
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of p2B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07349
synapse part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.066325
BRD-A52749901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08277
GSE193402_0_v_3_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE205976,GSE205978_1_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K49211735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49779
GC-46-CA74_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.310816
BRD-K81120201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90806
BRD-K14707716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.78483
GTEX-SNOS-0926-SM-4DM7A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24239
XPO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01629
GTEX-OIZG-1326-SM-2HMIQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.988315
TLN2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K49742819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2719
GSE179002_3_v_7_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r8 part of inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13057
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cortical collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.831
BRD-K39944607_32937_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CRCGN017_MCF10A.TP53.M_24H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.41843
ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
C-127 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.242
BRD-K91426044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.64806
CB-44-RT90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.267171
BRD-K12867552_THM-I-94_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A6-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MC-51-BT07_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.585215
BRD-K77908580_entinostat_HCC515_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TYK-nu	GDSC Cell Line Gene Expression Profiles	-1.0	-2.06677
GTEX-WHSE-3026-SM-3P5ZH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.9282
HOOK1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OHPM-0326-SM-33HCA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.86596
CRCGN016_MCF10A.TP53.M_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3931
colon	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.921351
VPS4B	Pathway Commons Protein-Protein Interactions	1.0	null
VZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.913091
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
EXOC3	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QLQW-0326-SM-447A8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65434
RAB14	Pathway Commons Protein-Protein Interactions	1.0	null
PMC5740759-40246_2017_131_MOESM1_ESM.xlsx-Table_S2-HSF1_CanSig_Genes-HSF1-CanSig_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
GE-68-FZ64_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.213359
EC-82-LV30_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.995655
CRCGN015_MCF10A.WT.HP_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.74271
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12891_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior digastric muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58465
BRD-K51061297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26804
arcuate nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.995223
TCF12_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JE-72-KV75_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.220029
GTEX-RWSA-0626-SM-2XCBD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04778
CKAP5	Pathway Commons Protein-Protein Interactions	1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GRIPAP1	Pathway Commons Protein-Protein Interactions	1.0	null
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01295
CRCGN013_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.21315
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.07254
Brain Lower Grade Glioma_LGG_TCGA-DB-5273-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Colon - Sigmoid	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.62725
CB-06-FE89_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.20905
CRCGN008_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9191
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	54.8549
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EP-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DC-08-CM08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.297645
BRD-K59159023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42451
BRD-K58607444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.61842
C-1300 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.276
head and face region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.81607
GSE146982_4_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN010_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.06634
GSE48812_4_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CB-55-AK76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.351104
GSE196104,GSE196106_2_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6608
OCUM-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.35722
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.73261
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.8922
PLA2G4A	Pathway Commons Protein-Protein Interactions	1.0	null
TFRC	Pathway Commons Protein-Protein Interactions	1.0	null
CA-60-RU13_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.238713
daudi	HPA Cell Line Gene Expression Profiles	-1.0	-0.888693
PMC12494973-41467_2025_63880_MOESM1_ESM.pdf-132-TEF_TEF	Rummagene Transcription Factor Associations 2026	1.0	null
VAPB	Pathway Commons Protein-Protein Interactions	1.0	null
EHD1	Pathway Commons Protein-Protein Interactions	1.0	null
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.2071
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN011_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1236
TZM-bl cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.953
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3661	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
AA-91-WB95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.222765
Main olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1283
JC-47-KK95_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.232811
BRD-K06792661_Narciclasine_NCIH1694_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
L-alpha-amino acid transmembrane transport	GO Biological Process Annotations 2023	1.0	null
BRD-K89501960	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.20849
CRCGN008_HEPG2_24H:O17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.11825
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A3YO-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VPS25	Pathway Commons Protein-Protein Interactions	1.0	null
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hepg2	HPA Cell Line Gene Expression Profiles	-1.0	-1.48805
BRD-K02708799_GSK-1059615_A375_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LU-65	GDSC Cell Line Gene Expression Profiles	-1.0	-2.16328
17616640-TableS1	GeneSigDB Published Gene Signatures	1.0	null
hsa-miR-4455	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
anion transport	GO Biological Process Annotations 2015	1.0	null
GSE129244_3_v_5_lmo2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ERBB3_knockout_239_GSE32129	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.02757
USF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
intermediate part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07648
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.971045
AF-01-FE42_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.411198
GSE234340_10_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K16485616_mocetinostat_HCC515_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC6715699-41467_2019_11785_MOESM4_ESM.xlsx-CSL_KD-Genes_differentially_expressed_upon_CSL_silencing_AR	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.87857
BRD-K76829357	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45352
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ChIP_NR0B1_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
tropicamide-4744	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-Row_names_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
S0-EE-YEKU_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.07431
GTEX-O5YW-0008-SM-4E3IE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06501
BRD-K86797399_pracinostat_MCF7_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-S4Z8-1826-SM-3K2BH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963226
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.573354
hsa-miR-302c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
CC-90-EX35_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.267961
RHOXF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39213
hsa-miR-762	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
essential	GeneRIF Biological Term Annotations	1.0	null
LF-45-MW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.22432
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054845
DUSP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19763
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
r7 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06144
CRCGN014_HEPG2_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.02494
GTEX-UTHO-0011-R11A-SM-3GIJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.919833
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.61538
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3752
Perturb_6089_KD_YBX3_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
CTCF_MCF-7_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SB-89-QK94_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.229856
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3832
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3959
IGFBPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43765
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN008_HEPG2_24H:O14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.96155
BRD-K51160592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46266
r8 part of lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.05671
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K45677596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24151
CRCGN015_MCF10A.WT.HP_24H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.23376
Cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K47175449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12028
GA-28-SS67_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.303677
GTEX-R55G-0626-SM-48FDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30651
CRCGN017_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.92852
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.25289
GSE138841_0_v_1_trim6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
regions	GeneRIF Biological Term Annotations	1.0	null
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.926524
RTN3	Pathway Commons Protein-Protein Interactions	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
mantle zone of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5666
CRCGN017_MCF10A.WT.HP_24H:A15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.479
Acute Myeloid Leukemia_LAML_TCGA-AB-2984-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
16622258-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
G protein-coupled GABA receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.374
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12342
H3K36me3_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K26026745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38769
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
YY1_KO_GSE39009_49_mouse_skeletal muscle (6 mo)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HS 683	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.97721
isoetharine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90632
Tcf21	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.7167
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22963
Lung adenocarcinoma_LUAD_TCGA-55-8094-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUN-27471255-CHONDROCYTES-MOUSE-RIB	ChEA Transcription Factor Targets 2022	1.0	null
BRD-A31107743_89671_HT29_24.0_h_0.09_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5199-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU2F2	ENCODE Transcription Factor Targets	1.0	null
Distal dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.797
HCC1143	CCLE Cell Line Gene CNV Profiles	-1.0	-1.80913
hsa-miR-155-5p	MiRTarBase microRNA Targets	1.0	null
CEBPB_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K81418486_vorinostat_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.261245
KC-17-YN77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.305482
PMC10684125-cm9-136-2712-s001.xlsx-Sheet1-CEBPD_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
GSE110178_1_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T6MN-0526-SM-32PMS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.89746
GSE180200,GSE180201_5_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S32W-1526-SM-4AD6Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29656
BRD-K91576495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43675
KYSE-50	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.93416
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
TC-59-QN21_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.22416
PB-59-HH22_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.209507
Basal ganglion	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.031
ESPNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27374
GTEX-QV31-0326-SM-447BM	GTEx Tissue Sample Gene Expression Profiles	1.0	2.14605
cytoplasmic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.201672
orbital frontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.828968
BRD-K51448234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01071
CRCGN017_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.91775
BRD-K08109215_I-BET_HCC515_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
G292CLONEA141B1	CCLE Cell Line Gene CNV Profiles	1.0	1.68
EF-20-MG69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.484618
GSE216273,GSE216292_0_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE138945,GSE138947_0_v_1_mboat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BACE2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00623006
AA-33-DN24_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.274571
H3K9me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A79768653_sirolimus_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K81418486_vorinostat_HA1E_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EPB41L2	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TR-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MX-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10350077-media-7.xlsx-Microglia_P_LPS_All_Up_GO-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GA-88-CF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200851
HS 38.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.56708
GSE122101,GSE122103_0_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OHPM-0008-SM-4E3IP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38864
GSE165122_0_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A56345662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01407
CB-87-RB49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.265766
BRD-K20526256_HG-14-10-04_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-133b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
BRD-K84060528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28842
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26021
GSE91015_0_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52536
BRD-K66754362	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86598
BRD-K50140147_NVP-TAE684_A375_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
A549_Resminostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0133318
Perturb_6029_KD_KHDRBS3_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
CA-10-RU23_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.395856
pontine nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07914
SFXN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00764
GSE193258,GSE193259_2_v_8_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
bephenium hydroxynaphthoate-3089	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PDCD6	Pathway Commons Protein-Protein Interactions	1.0	null
molecular	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
HCC1599	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74545
GTEX-POYW-1326-SM-48TCG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.82092
BRD-K87689816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52888
GSE188570,GSE188571_3_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K81418486_vorinostat_PHH_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN017_MCF10A.WT.HP_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1138
PMC8812561-pnas.2110428119.sd11.xlsx-Sheet1-The_overlapping_genes_of_LCDR_KD_RNA-seq_hnRNP_K_KD_RNA-seq_hnRNP_K_RIP-seq_and_eCLIP-seq_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K59317601_INK-128_A375_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MAFK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31207
BRD-K30853940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.32744
AB-18-YN11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.62268
GSE119564_1_v_0_zfp217_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COPZ1	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.878948
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE258991_5_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
TAF1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3456
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BX-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BC-54-ON71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.980753
BB-77-QQ71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.696281
AC-47-YZ27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.222297
GABPA_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
suggested	GeneRIF Biological Term Annotations	1.0	null
Amelanotic melanoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.595
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K01436366_XMD-1150_BT20_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-X4XY-1626-SM-46MVN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.916753
TRIM28_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-1426-SM-46MUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2739
GSE233049_2_v_0_atf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_1120_KD_CCND3_SRP325057	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.84092
GTEX-SUCS-1426-SM-4DM5W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2714
BRD-K94582694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.87352
KLF4-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-1226-SM-3NMA5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.22677
BRD-K51544265_cabozantinib_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K34092011_-666_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SYNE2	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN017_MCF10A.WT.HP_24H:I05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.44952
GTEX-SN8G-0326-SM-32PLG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69529
BRD-K90052868	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76585
organelle part	GO Cellular Component Annotations 2015	1.0	null
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE128730_0_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE81803,GSE81912_3_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DD-44-OX00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.229186
GTEX-S32W-2326-SM-2XCAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.855449
ricinine-2505	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFON-0226-SM-3GIKR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.983801
BRD-K16478699_PLX-4720_A375_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A94756469_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DC-51-WE27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.380504
BRD-K39925250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.24014
TBP	ENCODE Transcription Factor Targets	1.0	null
BRD-K88996418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66179
BRD-K74305673_IMD 0354_WSUDLCL2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
protein localization	GO Biological Process Annotations 2015	1.0	null
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
G142	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.4394
Prostate adenocarcinoma_PRAD_TCGA-HC-7745-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11024925-mmc3.xlsx-Gene_lists-MV411_FOS_ChIP_and_RNA_overlap_after_10_nM_Gilteritinib_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
Anterior cingulate area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5376
CRO-AP3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-A34806832_-666_ASC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC9537523-41467_2022_33364_MOESM7_ESM.xlsx-scores_wilcoxon_1_MONTH_ORG-EN2_n_EN2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A25736793_everolimus_A375_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A98444709_-666_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-372	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.2887
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7429-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AC-36-SY22_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.464527
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXP3-21729870-TREG-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
WC-09-GD62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.459845
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.984363
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.67086
GABPA_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE131660_1_v_0_piperlongumine_human	RummaGEO Drug Perturbation Signatures	1.0	null
DB-41-IH69_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.372412
pepstatin-1328	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CD-26-MB82_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.321187
amygdaloid complex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27892
FU97	CCLE Cell Line Gene CNV Profiles	1.0	1.55503
BRD-K86848211	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3546
Entorhinal area, medial part, ventral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.68761
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K09951645_dabrafenib_A375_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-P4QS-1326-SM-3NMCD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881192
CRCGN016_MCF10A.TP53.M_24H:F05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.54477
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NPJ8-1926-SM-3MJGB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00365
CRCGN017_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	10.0
Lingula (I), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07748
GI-ME-N	GDSC Cell Line Gene Expression Profiles	1.0	1.58529
KLC1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN009_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	10.0
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-52-7810-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT5A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE226249_5_v_4_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-C1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.71406
GSE199255,GSE199356_4_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prestwick-984-2903	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE213588_9_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ANXA9	Pathway Commons Protein-Protein Interactions	1.0	null
GSE96641_1_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.93113
BRD-K69840642_HDAC6 inhibitor ISOX_AGS_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Crus I, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01551
CRCGN013_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01996
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PSMA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0117834
BRD-K68060538	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25485
ARF1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K86797399_pracinostat_HT29_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K36me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lobeline-2763	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE57871_11_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
OE-18-ZX28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.26887
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OY-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
colon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.328262
primary motor cortex (area M1, area 4)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.86557
GTEX-Q2AG-0011-R1A-SM-2HMJI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28816
PRKAB1	Pathway Commons Protein-Protein Interactions	1.0	null
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.58582
Avian pallium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.031
BRD-K59317601_INK-128_A375_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AF-73-HJ84_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.368298
H3K36me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FD-62-ZB67_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.352661
KNS60	CCLE Cell Line Gene CNV Profiles	1.0	1.34484
GSE133927_1_v_0_meox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U4B1-0226-SM-4DXU8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00395
BRD-K53903639_480743.cdx_SNGM_6.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HTT	Pathway Commons Protein-Protein Interactions	1.0	null
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18834
BRD-K31758107	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68418
BRD-K02708799_GSK-1059615_A375_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K22380647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80072
VPS26A	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WFG8-1926-SM-4LVM1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52835
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE110178_2_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K13810148_-666_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN017_MCF10A.WT.HP_24H:M22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.414
sympathetic nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.379123
RCOR1	ENCODE Transcription Factor Targets	1.0	null
NCIH1993	DepMap CRISPR Gene Dependency	1.0	4.82598
BRD-K49282125	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.44366
CRCGN015_MCF10A_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.17862
mRNA_TCF3_20139965	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:C04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2654
Kidney Chromophobe_KICH_TCGA-KN-8427-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NC-27-AD53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.11222
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ED-81-ZH14_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.370011
CTCF	ENCODE Transcription Factor Targets	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
BD-04-NG34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.328318
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2IP-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148514_0_v_1_rreb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DA-59-ZD74_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.394952
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EIF2B5	Pathway Commons Protein-Protein Interactions	1.0	null
16293578-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN011_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.45095
Secondary Malignant Neoplasm Of Bone Marrow	DisGeNET Gene-Disease Associations	1.0	null
Medial preoptic nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26229
CC-90-EX35_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.204396
CRCGN016_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.65486
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.908188
VZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.875653
gata1_15860665_megakaryocytes_lof_mouse_gpl1261_gds1245	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.152521
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06096
primary motor cortex (area M1, area 4)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.834695
GSE206270_2_v_0_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GNAI3	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN016_MCF10A.WT.HP_24H:G07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.61674
BRD-K02708799_GSK-1059615_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K86797399_pracinostat_HCC515_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K00337317_NU-7441_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-OHPM-0426-SM-3TW8V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32869
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K93519076	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14937
GSE112761,GSE112767_4_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCFC1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4EP-3226-SM-3P5YR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976872
IA-27-CK10_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.308958
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A19037878_trichostatin A_HT29_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ARL8A	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K56343971_vemurafenib_MCF10A_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN008_HEPG2_24H:L14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.927
GTEX-WFG8-0626-SM-3GILJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6436
NCI-H3122	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.93416
Sarcoma_SARC_TCGA-IS-A3KA-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K86951121	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98901
USF1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10769314-NIHMS1954782-supplement-9.xlsx-Table_S7A-Table_S7A_Hippocampal_relative_gene_expression_from_post-KD_and_pre-KD_recipient_mice_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BA-88-HT15_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.209111
ATP6V0D1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE165122_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-V1D1-0008-SM-4JBIJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10715
GTEX-T2YK-0008-SM-4DM6M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853088
BRD-K02866760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64606
POLR2A_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.883077
Lung adenocarcinoma_LUAD_TCGA-50-5051-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVMIU	DepMap CRISPR Gene Dependency	1.0	5.70801
valproic acid-4464	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE118765_1_v_5_rreb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PDS5B	Pathway Commons Protein-Protein Interactions	1.0	null
GSE205976,GSE205978_3_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CE-37-XI06_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.350745
EFTUD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53657
BRD-K43594798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06736
WC-16-IR43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.312441
GSE112761,GSE112767_2_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-VJWN-0426-SM-3GIJI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26673
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01607
GSE147876,GSE147877_2_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100621_TCx_probable Alzheimer's disease_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.31964
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AW-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CA-10-RU23_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.662412
RASL11A	Pathway Commons Protein-Protein Interactions	1.0	null
COMMD3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE144231_2_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MOSPD2	Pathway Commons Protein-Protein Interactions	1.0	null
AB-18-YN11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.244305
SIX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHMP1B	Pathway Commons Protein-Protein Interactions	1.0	null
BA-39-OX47_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.363628
BRD-M86331534_BJM-ctd2-9_PC3_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BD-49-MD69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.642658
intermediate part of the arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.47688
MYC	ENCODE Transcription Factor Targets	1.0	null
BRD-K78816149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03783
H3K27ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
17910759-TableS5	GeneSigDB Published Gene Signatures	1.0	null
BRD-K26941844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30518
OB glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65627
BRD-K86797399_pracinostat_HCC515_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AP2A1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K02708799_GSK-1059615_A375_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE129241_3_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PTP4A1	Pathway Commons Protein-Protein Interactions	1.0	null
BA-88-HT15_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.00475
BRD-K75429775	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46067
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.8386
CRCGN014_HEPG2_3H:C17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06688
BRD-K90133770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.47535
EB-82-HZ30_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.267025
GTEX-X5EB-0526-SM-46MVP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.94834
GSE193258,GSE193259_5_v_13_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE77108_4_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EHF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.1733
BRD-A29901043_KIN001-127_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K41355839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.33132
CRCGN009_HEPG2_24H:L09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.51294
GTEX-P44H-0226-SM-2XCEU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2147
PMC12354803-42003_2025_8643_MOESM2_ESM.xlsx-2w_TP63_positive-Gene_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN008_HEPG2_24H:O16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.2352
BRD-K59587063	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01093
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OB-20-LP90_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.266492
GPRC5A	Pathway Commons Protein-Protein Interactions	1.0	null
IF-86-JG83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.241922
hsa-miR-326	TargetScan Predicted Conserved microRNA Targets	1.0	0.389112
YY1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.880771
GSE147943_0_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_GM10847_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.5075
EXOC1	Pathway Commons Protein-Protein Interactions	1.0	null
L-glutamate transmembrane transport	GO Biological Process Annotations 2025	1.0	null
forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null