association	dataset	threshold value	standardized value
CRCGN014_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.2109
CRCGN014_HEPG2_3H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.29941
CRCGN015_MCF10A.WT.HP_24H:K18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.64993
CRCGN011_HEPG2_24H:C03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.25985
CRCGN009_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	10.0
CRCGN015_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.80761
CRCGN015_HEPG2_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.72591
CRCGN015_MCF10A.TP53.M_24H:F17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3742
PMC4773428-ncomms10751-s5.xlsx-S_Table_4-Supplementary_Data_4_RUNX1_responsive_genes_in_the_presence_and_absence_of_estradiol_E2_in_MCF7_cells_FC_1_5_p_0_05_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4686
CRCGN012_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.56387
CRCGN011_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8593
Childhood acute myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.039
BARHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5654
CRCGN017_MCF10A.TP53.M_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.02938
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5384
CRCGN016_MCF10A.TP53.M_24H:O18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.52386
CRCGN015_HEPG2_48H:G04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.42725
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3766
CRCGN014_HEPG2_24H:H18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.48823
CRCGN017_MCF10A.TP53.M_24H:K03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07989
CRCGN010_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5553
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4472
L-type voltage-gated calcium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.013
CRCGN009_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.6127
CRCGN011_HEPG2_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3792
PMC10243915-uxad037_suppl_supplementary_table_s1a.pdf-551-HBP1_HBP1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_HEPG2_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.20965
Coats disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.384
CRCGN008_HEPG2_24H:G24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.6479
CRCGN017_MCF10A.TP53.M_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.50948
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.3694
CRCGN017_MCF10A.WT.HP_24H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.51895
DD-43-WW40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.360226
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.6544
NFYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2405
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3743
CRCGN015_MCF10A.TP53.M_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1714
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1467
Sexual health disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.166
CRCGN014_HEPG2_3H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.57014
CRCGN017_MCF10A.WT.HP_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.2398
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6793
PMC10774440-41531_2023_624_MOESM3_ESM.xlsx-MLi2_TRAPD_P_DOM_PD_0_05_allele-Gene_refGene_SOX10	Rummagene Transcription Factor Associations 2026	1.0	null
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.3339
CRCGN015_HEPG2_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.19463
CRCGN015_MCF10A.TP53.M_24H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06225
CRCGN016_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.83464
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5933
CRCGN016_MCF10A.TP53.M_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.97755
CRCGN015_MCF10A.TP53.M_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.0354
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_12hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4725
CRCGN016_MCF10A.WT.HP_24H:D04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.9491
CRCGN009_HEPG2_24H:F19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.8264
Tear gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.352
CRCGN009_HEPG2_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.14804
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.0044
CRCGN011_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.89315
proteasome-mediated ubiquitin-dependent protein catabolic process	GO Biological Process Annotations 2025	1.0	null
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.0598
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.7808
CRCGN015_MCF10A_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.8964
CRCGN015_MCF10A_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.81914
CRCGN015_MCF10A_48H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.9908
CRCGN015_HEPG2_48H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.45285
CRCGN015_MCF10A.WT.HP_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.37839
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4686
CRCGN015_HEPG2_48H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.59547
CRCGN014_HEPG2_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.86987
GSE214212_2_v_0_chd6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.73955
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.7201
CRCGN016_MCF10A.TP53.M_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10816
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.5943
CRCGN014_HEPG2_24H:A03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.55181
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0824
ZNF708	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.523
CRCGN016_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.6124
OTX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1341
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.258
CRCGN016_MCF10A.TP53.M_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.8142
CRCGN014_HEPG2_24H:B08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5511
CRCGN017_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.99025
CRCGN009_HEPG2_24H:L08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.5322
CRCGN015_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.72027
CRCGN013_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.0022
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.479317
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7283
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	146.877
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5876
CRCGN015_MCF10A_48H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.33926
CRCGN016_MCF10A.TP53.M_24H:F05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.34252
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6773
CRCGN014_HEPG2_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7441
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6508
CRCGN015_HEPG2_48H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.70417
NRL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5288
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2309
ZBTB12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6576
CRCGN013_HEPG2_24H:B07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.32155
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_24hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.0213
CRCGN013_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07316
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9886
RHOXF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.1647
CRCGN016_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.66907
CRCGN015_HEPG2_48H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.36572
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.9059
CRCGN016_MCF10A.TP53.M_24H:P12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.16796
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.557
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4825
CRCGN015_HEPG2_48H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.78702
CRCGN010_HEPG2_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.90581
Biceps	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.712
CRCGN009_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.5348
CRCGN009_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.97255
RUNX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1764
CRCGN010_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.27675
CRCGN012_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.27727
CRCGN015_MCF10A.TP53.M_24H:O22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.37855
CRCGN017_MCF10A.TP53.M_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.6825
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.391
CRCGN014_HEPG2_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.97562
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5221
CRCGN016_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.72015
CRCGN015_HEPG2_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.53249
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0824
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	82.8107
SMAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8308
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5287
CRCGN014_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.32829
CRCGN014_HEPG2_24H:P01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.57416
Rhabdomyosarcoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.816
PITX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0975
CRCGN015_HEPG2_48H:J17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.81241
CRCGN015_MCF10A_48H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.78383
CRCGN015_HEPG2_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.32572
CRCGN010_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.4823
ubiquitin-dependent protein catabolic process	GO Biological Process Annotations 2025	1.0	null
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.8163
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9548
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9011
CRCGN014_HEPG2_3H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0056
CRCGN017_MCF10A.WT.HP_24H:E01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12434
ubiquitin-like ligase-substrate adaptor activity	GO Molecular Function Annotations 2025	1.0	null
CRCGN012_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.8763
CRCGN014_HEPG2_3H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.9036
CRCGN009_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.61622
CRCGN015_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6044
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.9686
CRCGN017_MCF10A.WT.HP_24H:E10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.4314
Rd	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.914
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.0245
Liposarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.239
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.282
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	84.2819
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5993
CRCGN016_MCF10A.WT.HP_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.678
CRCGN014_HEPG2_3H:E07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0278
CRCGN015_HEPG2_48H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.45196
Retroperitoneal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.993
GSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.827
CRCGN016_MCF10A.TP53.M_24H:E17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22725
CRCGN015_HEPG2_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.68722
CRCGN015_HEPG2_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.05311
CRCGN015_HEPG2_48H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.79018
CRCGN016_MCF10A.WT.HP_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17213
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.5736
CRCGN015_HEPG2_48H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22411
Autoimmune disease of exocrine system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.243
CRCGN014_HEPG2_3H:M21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3912
CRCGN016_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.04824
CRCGN017_MCF10A.TP53.M_24H:G11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.27735
GSC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.75
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4143
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	78.1496
CRCGN011_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.4142
CRCGN015_HEPG2_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.59312
CRCGN015_HEPG2_48H:F16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.69315
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9921
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2026
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.5
CRCGN014_HEPG2_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0272
PMC7794364-41540_2020_161_MOESM3_ESM.xlsx-U87MG_Unique_-_PPH2_predictions-Gene_Sym_SMAD9	Rummagene Transcription Factor Associations 2026	1.0	null
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2366
Cul2-RING ubiquitin ligase complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Synaptic vesicle protein transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.235
CRCGN016_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.31731
GSE258991_5_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN009_HEPG2_24H:F20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.9996
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.212
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5489
CRCGN016_MCF10A.WT.HP_24H:F05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.10977
CRCGN015_MCF10A_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.9362
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9646
Cul2-RING ubiquitin ligase complex	GO Cellular Component Annotations 2025	1.0	null
CRCGN008_HEPG2_24H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.87455
CRCGN015_HEPG2_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.96529
CRCGN012_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.88315
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.2883
CRCGN015_HEPG2_48H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.33268
CRCGN015_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.60395
CRCGN016_MCF10A.TP53.M_24H:E20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.72621
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5575
CRCGN017_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4098
CRCGN016_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.37013
CRCGN015_HEPG2_48H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.14624
CRCGN014_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.23895
CRCGN016_MCF10A.TP53.M_24H:C10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03868
CRCGN015_MCF10A.TP53.M_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.78245
CRCGN014_HEPG2_3H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.84317
CRCGN015_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0214
Rhabdomyosarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.392
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.641
CRCGN015_HEPG2_48H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.31742
CRCGN017_MCF10A.WT.HP_24H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00769
Gender incongruence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.43
cullin-RING ubiquitin ligase complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
FE-59-BC81_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.276265
CRCGN012_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7648
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.725
CRCGN015_HEPG2_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.30455
PMC10115638-41591_2023_2255_MOESM4_ESM.xlsx-CNS_NB_FOXR2_deletions-Unnamed_2_FOXR2	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN009_HEPG2_24H:C08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04219
CRCGN016_MCF10A.TP53.M_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.32565
CRCGN015_HEPG2_48H:M17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.69037
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.581
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4986
CRCGN016_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.67055
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2287
CRCGN016_MCF10A.TP53.M_24H:D15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11993
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2819
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3794
CRCGN015_MCF10A_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.20302
CRCGN016_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.85895
CRCGN011_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.6388
CRCGN016_MCF10A.TP53.M_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8322
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.6384
CRCGN009_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.10558
cullin-RING ubiquitin ligase complex	GO Cellular Component Annotations 2025	1.0	null
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3301
proteasomal protein catabolic process	GO Biological Process Annotations 2025	1.0	null
CRCGN015_HEPG2_48H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.82086
CRCGN008_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.5242
CRCGN017_MCF10A.WT.HP_24H:K22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.97585
Lipoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.475
CRCGN013_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.69758
PMC8481886-Table_1.xlsx-A_subsets-iMSC_fetal_MSC_UC_MSC_adipose_tissue_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.72807
CRCGN009_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5961
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.21239
Facioscapulohumeral muscular dystrophy 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.247
CRCGN010_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.14165
CRCGN015_HEPG2_48H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.58596
CRCGN017_MCF10A.WT.HP_24H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22295
CRCGN009_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.08039
PPARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.7857
IRF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3436
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	97.6928
CRCGN017_MCF10A.WT.HP_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17515
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5106
INA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.849
CRCGN015_HEPG2_48H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.42324
CRCGN015_HEPG2_48H:I06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2137
CRCGN015_MCF10A.TP53.M_24H:P15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.08115
CRCGN015_HEPG2_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.02605
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6389
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5753
CRCGN016_MCF10A.TP53.M_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.45281
CRCGN009_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.40661
CRCGN015_MCF10A_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.71885
CRCGN013_HEPG2_24H:I15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.16284
CRCGN009_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.48821
CRCGN014_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.97163
Retinal telangiectasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.324
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_3hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ZBED2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5405
CRCGN014_HEPG2_3H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.54567
CRCGN015_HEPG2_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7339
CRCGN013_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.9962
CRCGN015_HEPG2_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.93701
CRCGN011_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.44515
PMC8120133-supplementarytables_ddab063.xlsx-Table_S2-Table_S2_Differentially_expressed_genes_in_DUX4-fl_and_DUX4-s_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7241
CRCGN015_HEPG2_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.18478
CRCGN009_HEPG2_24H:A15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.12978
BA-40-IU73_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.414124
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7093
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.993
CRCGN014_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.80607
CRCGN017_MCF10A.TP53.M_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.5193
CRCGN016_MCF10A.WT.HP_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30015
CRCGN016_MCF10A.WT.HP_24H:M01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.65876
CRCGN015_MCF10A.WT.HP_24H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.2726
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0686
CRCGN017_MCF10A.WT.HP_24H:E04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.72529
Malignant fibrous histiocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.628
CRCGN015_HEPG2_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.72126
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.1619
CRCGN010_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5669
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.2813
CRCGN016_MCF10A.WT.HP_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.82105
CRCGN013_HEPG2_24H:H22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.12183
CRCGN016_MCF10A.TP53.M_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.64574
CRCGN013_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5048
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6277
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0658
CRCGN016_MCF10A.TP53.M_24H:L11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.08162
CRCGN011_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4432
SMAD5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6124
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.6411
CRCGN009_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.34336
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9065
CRCGN016_MCF10A.WT.HP_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.50828
CRCGN016_MCF10A.WT.HP_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.2647
CRCGN012_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24481
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3087
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0854
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2753
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.261
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.2034
Sjogren's syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.243
CRCGN016_MCF10A.TP53.M_24H:C18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.05217
CRCGN016_MCF10A.TP53.M_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.31255
PITX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4526
CRCGN015_HEPG2_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	10.0
Facioscapulohumeral muscular dystrophy 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.232
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7478
IRF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.1597
Childhood leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.199
CRCGN016_MCF10A.TP53.M_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.95605
CRCGN016_MCF10A.TP53.M_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.73246
CRCGN016_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.58396
CRCGN015_HEPG2_48H:G02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13705
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8403
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6811
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2393
CRCGN011_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.1414
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8481
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3555
CRCGN015_MCF10A.WT.HP_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.7869
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.1449
CRCGN015_HEPG2_48H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.08604
CRCGN015_HEPG2_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.54535
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	89.0997
CRCGN015_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.21276
CRCGN015_HEPG2_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.26604
CRCGN015_HEPG2_48H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.5082
CRCGN017_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.79053
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3214
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_6_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN014_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.416
CRCGN014_HEPG2_3H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.35705
CRCGN017_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.95305
PMC10774440-41531_2023_624_MOESM3_ESM.xlsx-MLi2_TRAPD_P_DOM_PD_0_05_allele-GENE_SOX10	Rummagene Transcription Factor Associations 2026	1.0	null
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.544
CRCGN016_MCF10A.TP53.M_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.32735
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.64