association	dataset	threshold value	standardized value
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.858749
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.868339
HOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3029
HOXA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8814
regulation of retinoic acid receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6022-01A-21R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30132
CPCN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.89109
ZR75B	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.72585
PRAME family/Leucine-rich repeat-containing protein 14	InterPro Predicted Protein Domain Annotations	1.0	null
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.80275
PMC12909843-41467_2026_68388_MOESM4_ESM.xlsx-fig3g-up-regulated_gene_expression_in_OTX2-KO_8CLCs_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
negative regulation of macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17085
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.995585
Brain Lower Grade Glioma_LGG_TCGA-P5-A72U-01A-31R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1224-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
H3K9me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
cullin-RING ubiquitin ligase complex	GO Cellular Component Annotations 2025	1.0	null
SCLC21H	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
hsa-miR-335-5p	MiRTarBase microRNA Targets	1.0	null
NFYB-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NAMALWA	CCLE Cell Line Gene CNV Profiles	1.0	1.38423
TP53	JASPAR Predicted Transcription Factor Targets	1.0	null
negative regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.663815
GRANTA-519	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.59325
NCI-H524	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NFYA-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PSMG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2836
CTCF	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
negative regulation of cell communication	GO Biological Process Annotations 2015	1.0	null
regulation of cellular biosynthetic process	GO Biological Process Annotations 2015	1.0	null
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32632
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.52
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A199-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1601
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.42031
nuclear hormone receptor binding	GO Molecular Function Annotations 2015	1.0	null
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3575
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.92496
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3764
CTCF_GM13976_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS-28BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37103
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10541
CAL148	CCLE Cell Line Gene CNV Profiles	-1.0	-1.81366
496100420_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04462
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.75762
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.929663
GB1	CCLE Cell Line Gene CNV Profiles	1.0	2.08018
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.839907
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30204
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.975405
EBNA1-20929547-CHIP-SEQ-RAJI-CELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Lung adenocarcinoma_LUAD_TCGA-69-8253-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cranial nerve malignant neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.46
MOTN1	CCLE Cell Line Gene CNV Profiles	1.0	2.44472
PMC12179083-Table_6.xlsx-VCF_Variants_Master_File-Gene_TBX1	Rummagene Transcription Factor Associations 2026	1.0	null
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8927
regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
regulation of signal transduction	GO Biological Process Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5399-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.314
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07693
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.37263
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1172
negative regulation of transcription, dna-templated	GO Biological Process Annotations 2015	1.0	null
PMC10709143-41556_2023_1271_MOESM9_ESM.xls-Up_in_PAX7-Target_name_PAX7	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9D4-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6162
HH	CCLE Cell Line Gene CNV Profiles	1.0	1.43033
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7421-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sinonasal undifferentiated carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.785
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22875
regulation of programmed cell death	GO Biological Process Annotations 2015	1.0	null
KO52	CCLE Cell Line Gene CNV Profiles	1.0	1.36875
regulation of cell communication	GO Biological Process Annotations 2015	1.0	null
hsa-miR-548d-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
MEOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3284
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2905
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.929663
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_6_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
MEWO	CCLE Cell Line Gene CNV Profiles	1.0	1.3531
MEWO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.93032
NCIH1385	CCLE Cell Line Gene CNV Profiles	-1.0	-2.27731
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30204
SF295	COSMIC Cell Line Gene Mutation Profiles	1.0	null
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5K0-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DLX1_02_55	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.62803
NANOG-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40951
NCI-H2373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46001
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
negative regulation of cell death	GO Biological Process Annotations 2015	1.0	null
Olfactory organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.153
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7518
regulation of developmental process	GO Biological Process Annotations 2015	1.0	null
IGR1	CCLE Cell Line Gene CNV Profiles	1.0	2.44112
MEOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3588
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.86641
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50028
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3335-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3918
negative regulation of gene expression	GO Biological Process Annotations 2015	1.0	null
KYSE270	CCLE Cell Line Gene CNV Profiles	1.0	1.69489
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12297
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.59
SBC5	CCLE Cell Line Gene CNV Profiles	1.0	1.67391
regulation of biosynthetic process	GO Biological Process Annotations 2015	1.0	null
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26271
C3A	CCLE Cell Line Gene CNV Profiles	1.0	1.80331
GSE242521,GSE242522_0_v_1_mettl3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KMRC2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39547
MDAMB157	CCLE Cell Line Gene CNV Profiles	1.0	1.56269
negative regulation of response to stimulus	GO Biological Process Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A641-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus	GAD Gene-Disease Associations	1.0	null
Sarcoma_SARC_TCGA-SG-A6Z7-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1944	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51426
KYSE-150	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02971
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1601
positive regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
KMS28BM	CCLE Cell Line Gene CNV Profiles	1.0	1.5587
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.92496
transcription factor binding	GO Molecular Function Annotations 2015	1.0	null
FOXF2	JASPAR Predicted Transcription Factor Targets	1.0	null
proteasomal protein catabolic process	GO Biological Process Annotations 2025	1.0	null
Cul2-RING ubiquitin ligase complex	GO Cellular Component Annotations 2025	1.0	null
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9332
COLO668	CCLE Cell Line Gene CNV Profiles	1.0	1.86599
MOLT-16	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_307_KD_TPRX1/TPRX2_SRP361145	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.02694
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.62108
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16259
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.78941
Paranasal sinus cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.655
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.92496
negative regulation of retinoic acid receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.634
regulation of gene expression	GO Biological Process Annotations 2015	1.0	null
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.929663
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51H-06A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ubiquitin-like ligase-substrate adaptor activity	GO Molecular Function Annotations 2025	1.0	null
NB1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5304
regulation of transcription, dna-templated	GO Biological Process Annotations 2015	1.0	null
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2267
Primitive endoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.021
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17158
Lung squamous cell carcinoma_LUSC_TCGA-77-8009-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.2595
PHF8-20622853-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZR7530	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33413
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.88452
negative regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
ZBTB12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.995
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.75762
Nasal cavity carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.771
BFTC-909	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.454
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0738
PMC8791933-41598_2022_4817_MOESM3_ESM.xlsx-DUX4_signature_genes-Unnamed_2_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.976141
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5971-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.45257
HEL9217	CCLE Cell Line Gene CNV Profiles	1.0	1.34585
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.92496
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A634-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCPAP	CCLE Cell Line Gene CNV Profiles	1.0	1.38215
184A1N4	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.0398
HCC1187	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.590762
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A4ZP-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
SUPT11	CCLE Cell Line Gene CNV Profiles	1.0	1.65064
regulation of cell differentiation	GO Biological Process Annotations 2015	1.0	null
COV318	CCLE Cell Line Gene CNV Profiles	1.0	1.39473
CORL88	CCLE Cell Line Gene CNV Profiles	1.0	1.71028
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03047
retinoic acid receptor binding	GO Molecular Function Annotations 2015	1.0	null
regulation of rna biosynthetic process	GO Biological Process Annotations 2015	1.0	null
NFYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.225
Hippocampus	dbGAP Gene-Trait Associations	1.0	0.369017
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28801
PK-45P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25468
SUM159PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.01554
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.987452
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.21239
protein binding	GO Molecular Function Annotations 2015	1.0	null
positive regulation of biological process	GO Biological Process Annotations 2015	1.0	null
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9061
regulation of nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21664
regulation of signaling	GO Biological Process Annotations 2015	1.0	null
cullin-RING ubiquitin ligase complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
H2731	COSMIC Cell Line Gene CNV Profiles	-1.0	-5.12655
HNFA-21074721-CACO-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
496100418_TCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.76772
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21505
SUM225CWN	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.59985
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-A4D5-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.533
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32632
NCIH1563	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47863
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF549	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.2652
NCI-H2795	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.63386
Prostate adenocarcinoma_PRAD_TCGA-HC-A8D1-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7738-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RH-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH209	CCLE Cell Line Gene CNV Profiles	-1.0	-2.22025
SKMEL28	CCLE Cell Line Gene CNV Profiles	1.0	1.52468
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61J-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of response to stimulus	GO Biological Process Annotations 2015	1.0	null
negative regulation of macromolecule biosynthetic process	GO Biological Process Annotations 2015	1.0	null
HOXA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9836
MCF7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.21868
regulation of nucleic acid-templated transcription	GO Biological Process Annotations 2015	1.0	null
Nasal cavity cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.711
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0985
negative regulation of cellular macromolecule biosynthetic process	GO Biological Process Annotations 2015	1.0	null
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.98649
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10541
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.1726
PA-TU-8988S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07693
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.62108
biological regulation	GO Biological Process Annotations 2015	1.0	null
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.914975
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.18043
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7044-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
negative regulation of biological process	GO Biological Process Annotations 2015	1.0	null
proteasome-mediated ubiquitin-dependent protein catabolic process	GO Biological Process Annotations 2025	1.0	null
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.80275
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2208
496100419_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.36124
PRPF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29125
Olfactory neuroblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.568
Epi	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.345
NIHOVCAR3	CCLE Cell Line Gene CNV Profiles	1.0	1.95209
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4224-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7046-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_248_KD_TPRX1/TPRX2/TPRXL_SRP361145	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.08196
cervix uteri	GTEx Tissue Gene Expression Profiles	1.0	1.41832
GSE145628,GSE145629_1_v_0_myrf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25119
Morula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.909
ETV1-20927104-GIST48-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.976141
molecular_function	GO Molecular Function Annotations 2015	1.0	null
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4485
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16358
RBPJ-21746931-IB4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.975405
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.15296
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37103
GATA6-21074721-CACO-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC8791933-41598_2022_4817_MOESM3_ESM.xlsx-DUX4_signature_genes-Unnamed_1_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-8460-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44617
negative regulation of biosynthetic process	GO Biological Process Annotations 2015	1.0	null
negative regulation of developmental process	GO Biological Process Annotations 2015	1.0	null
LN319	CCLE Cell Line Gene CNV Profiles	1.0	1.94405
negative regulation of nucleobase-containing compound metabolic process	GO Biological Process Annotations 2015	1.0	null
CHP212	CCLE Cell Line Gene CNV Profiles	-1.0	-1.93131
TP63	JASPAR Predicted Transcription Factor Targets	1.0	null
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.92496
ONCODG1	CCLE Cell Line Gene CNV Profiles	1.0	1.46473
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.98649
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04441
KPNSI9S	CCLE Cell Line Gene CNV Profiles	-1.0	-2.98426
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37663
ZNF140	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.8957
regulation of apoptotic process	GO Biological Process Annotations 2015	1.0	null
CDX2-21074721-CACO-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TV-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0659
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.929663
negative regulation of cell differentiation	GO Biological Process Annotations 2015	1.0	null
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.929663
regulation of macromolecule biosynthetic process	GO Biological Process Annotations 2015	1.0	null
negative regulation of cellular biosynthetic process	GO Biological Process Annotations 2015	1.0	null
hsa-miR-371-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
hsa-miR-515-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.54963
GATA6-21074721-CACO-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
KPNRTBM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54638
regulation of rna metabolic process	GO Biological Process Annotations 2015	1.0	null
HOXB7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.662
positive regulation of cell proliferation	GO Biological Process Annotations 2015	1.0	null
hormone receptor binding	GO Molecular Function Annotations 2015	1.0	null
PMC12179083-Table_6.xlsx-VCF_Variants_Master_File-Gene_symbol_TBX1	Rummagene Transcription Factor Associations 2026	1.0	null
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.544
SNU-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45392
GRANTA519	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32172
NCIH292	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68645
EB2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SIMA	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64257
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09535
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32992
H3K9me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4641-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.89082
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1605
KLE	CCLE Cell Line Gene CNV Profiles	1.0	1.41111
Prostate adenocarcinoma_PRAD_TCGA-EJ-5526-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.9972
hsa-miR-4669	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.908298
496100355_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	17.3829
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20I-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.704128
NCI-H1573	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.975405
binding	GO Molecular Function Annotations 2015	1.0	null
IMR32	CCLE Cell Line Gene CNV Profiles	-1.0	-1.85398
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
ubiquitin-dependent protein catabolic process	GO Biological Process Annotations 2025	1.0	null
CHP126	CCLE Cell Line Gene CNV Profiles	-1.0	-1.72787
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.882489
NCIH510	CCLE Cell Line Gene CNV Profiles	1.0	1.63621
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.908298
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.990427
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12371
Prostate adenocarcinoma_PRAD_TCGA-HC-8265-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
Cul2-RING ubiquitin ligase complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MR-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA-MB-435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.32802
NAMALWA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.66561
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40699
regulation of macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
negative regulation of rna biosynthetic process	GO Biological Process Annotations 2015	1.0	null
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.128
negative regulation of apoptotic process	GO Biological Process Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4223-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of cell proliferation	GO Biological Process Annotations 2015	1.0	null
RT4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46332
NCIH28	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46841
H9 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.087
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.858749
496100456_TCx_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.62562
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.01411
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4148-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
HOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1244
negative regulation of nucleic acid-templated transcription	GO Biological Process Annotations 2015	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A262-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of cellular macromolecule biosynthetic process	GO Biological Process Annotations 2015	1.0	null
negative regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
OVSAHO	CCLE Cell Line Gene CNV Profiles	1.0	2.14735
negative regulation of rna metabolic process	GO Biological Process Annotations 2015	1.0	null
negative regulation of signaling	GO Biological Process Annotations 2015	1.0	null
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.839907
CTCF-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25Z-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1599	CCLE Cell Line Gene CNV Profiles	-1.0	-2.5062
hsa-miR-519e	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.67439
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3931
biological_process	GO Biological Process Annotations 2015	1.0	null
GCT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OTX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8102
Te	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.14
hsa-miR-3613-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Extraembryonic tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.863
negative regulation of programmed cell death	GO Biological Process Annotations 2015	1.0	null
regulation of nucleobase-containing compound metabolic process	GO Biological Process Annotations 2015	1.0	null
Malignant olfactory nerve neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.568
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8629
SUPHD1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.9766
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HC-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of cell death	GO Biological Process Annotations 2015	1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.929663
regulation of primary metabolic process	GO Biological Process Annotations 2015	1.0	null
receptor binding	GO Molecular Function Annotations 2015	1.0	null
KPNYN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57719
ZNF135	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.9968
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05288
RAJI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17158
CEBPA-26348894-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TBL1-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JY-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_226_KD_TPRX1/TPRX2/TPRXL_SRP361145	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.02754
negative regulation of nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5790-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMAD2/3-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
negative regulation of signal transduction	GO Biological Process Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4691-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.976141
SNU1272	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36207
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5561-01A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12297
regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
KURAMOCHI	CCLE Cell Line Gene CNV Profiles	1.0	1.36691
GSE94849_6_v_0_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
G140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.839907
PMC10115638-41591_2023_2255_MOESM4_ESM.xlsx-CNS_NB_FOXR2_deletions-Unnamed_2_FOXR2	Rummagene Transcription Factor Associations 2026	1.0	null
NH6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32852
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49965
PRAME family	InterPro Predicted Protein Domain Annotations	1.0	null
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.867051
HCC2218	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65974
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12297
H3K9me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5183-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15546
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1701