association	dataset	threshold value	standardized value
GLO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89491
TOPORS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74634
disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.256228
intrinsic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.163938
heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.05736
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.436
body of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.934763
VCAP	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNU-283	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ATG16L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4651
MAP1LC3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64058
lingual gyrus, left, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.28831
Intestinal infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.081
NUDT13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73439
COVID-19	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.355
Thylakoid light-harvesting complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.954
CCDC137	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06719
Squamous Cell Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
PTGR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56898
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.283899
GTEX-QLQ7-1626-SM-2S1R8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833157
NDUFA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66123
MARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66308
496100315_TCx_no dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04232
ZNF444	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16484
Acute Myeloid Leukemia_LAML_TCGA-AB-3007-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACBD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48389
CTCF_GM13976_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PATU8902	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64033
Laryngotracheitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.104
ARPP19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25846
SNU1033	CCLE Cell Line Gene CNV Profiles	1.0	2.09548
stomach	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.106353
tooth enamel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.357802
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.31208
GTEX-N7MS-0225-SM-4E3HO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36749
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.17119
RPL30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38296
HS-SY-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.58
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IJ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pilus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.564
COMMD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05983
GTEX-X585-0011-R5A-SM-46MVI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90845
endocrine gland cancer	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.256228
eralpha	GeneRIF Biological Term Annotations	1.0	null
tb1lu	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.782
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6914-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C2orf15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78373
496100328_TCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.71921
COR-L88	COSMIC Cell Line Gene Mutation Profiles	1.0	null
icSARS CoV_36Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.37317
hsa-miR-1272	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11486
Salivary gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	3.602
PLOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26711
Adrenocortical carcinoma_ACC_TCGA-OR-A5LB-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZSCAN31	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.2321
MAPK12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61914
body of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.67973
SLC44A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27022
AUP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96111
Neonatal Alloimmune Thrombocytopenia	DisGeNET Gene-Disease Associations	1.0	null
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6729
structure	GeneRIF Biological Term Annotations	1.0	null
ID4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57807
GBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22331
GTEX-WHSE-0011-R3A-SM-3P5ZM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890022
BCL6-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
IFT57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07635
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.91855
RECQL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0363
GTEX-QV44-1926-SM-2S1RF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07543
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05042
N-terminal protein acetyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.108
ZFPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22927
QPRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24094
NFYA-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RPS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4681
ZNF549	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22694
KIF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85554
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.25259
CHMP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55008
Swine influenza	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.504
GTEX-PWO3-0011-R6A-SM-2I5F3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25099
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.225
TMEM70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.678
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.927966
aggressive periodontitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.629635
RASD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49963
GTEX-NPJ8-0011-R10A-SM-2YUMO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49212
CRCGN017_MCF10A.WT.HP_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1203
DBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08271
MATCAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74836
TCEA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28581
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3R5-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
F5	DepMap CRISPR Gene Dependency	1.0	2.53206
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08608
abnormality of the abdomen	GWASdb SNP-Phenotype Associations	1.0	0.069042
ZNF816	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.2564
Liver hepatocellular carcinoma_LIHC_TCGA-T1-A6J8-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.WT.HP_24H:E21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.55268
WM-266-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.577
p2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.734
EWSR1	ChEA Transcription Factor Targets	1.0	null
PLCD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18119
POMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43479
SLC41A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57976
CL1-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.082
BTBD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80087
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A4BB-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WQUQ-0426-SM-3MJFU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12676
DDAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16017
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895484
KYAE-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NHLRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29666
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01172
SLC17A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45532
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11592
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7646-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MANBA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98959
GSE111247_14_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Tumor Cell Invasion	DisGeNET Gene-Phenotype Associations	1.0	null
RPL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96228
KLF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.3558
mucous cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.295655
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.895961
PMC9069107-Table_5.xlsx-Table_S5-Table_S5_The_differences_of_significantly_mutated_genes_and_their_CNVs_between_the_high-immunity_and_low-immunity_cohort_The_CNVs_of_NBPF1_PARM1_and_TP53_were_missing_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7889-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.996415
HEATR5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19151
ENTPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4305
NCI-H1092	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RHPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1053
RAB12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36701
CRCGN016_MCF10A.TP53.M_24H:N11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06074
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_10223_KD_FOXC1_SRP068208	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.824056
BJ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.618
LIN7C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.69326
TYRO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0017
SEPTIN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90206
ALX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50524
COLO-783	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XLM4-0011-R7A-SM-4AT5L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25487
KIAA1143	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43794
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20X-01A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
large intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.447192
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.84995
GTEX-Q2AG-2926-SM-2HMJ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05805
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.1281
GTEX-QVUS-0011-R10A-SM-3GIK3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06004
PMC9643473-Table1.xls-MAF_0_005-Gene_refGeneWithVer_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
HS-445	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FUBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10576
LIG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47034
abomasum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.182834
EGR4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.371
ovary cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.247399
Stomach Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
MDA-MB-175-VII	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WHSE-0011-R5A-SM-3P5ZO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3278
Distal tip cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.776
PPP6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91081
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056073
Immune Thrombocytopenic Purpura	DisGeNET Gene-Disease Associations	1.0	null
LPS853	DepMap CRISPR Gene Dependency	1.0	3.3692
NPFF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41682
DMS53	DepMap CRISPR Gene Dependency	1.0	2.38146
Metacercaria	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.138
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939744
MAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74814
Gingivitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.341
IRX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43355
GTEX-T5JC-2426-SM-3NMDB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955413
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44543
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.69945
Urinary tract infection	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.045
Rectum adenocarcinoma_READ_TCGA-EI-6507-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB7A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6936
salivary gland	HPA Tissue Gene Expression Profiles	1.0	2.24804
GTEX-XMD1-0011-R5A-SM-4AT47	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13969
CSNK1E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50465
ETV7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3295
H2BC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43642
Von Willebrand Disease	DisGeNET Gene-Disease Associations	1.0	null
KATOIII	DepMap CRISPR Gene Dependency	1.0	2.50323
AS-30D cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.611
CTH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15237
RPS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16154
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.851901
NKX2-3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81485
CDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55352
ETV4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8834
496100330_PCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0445
Von Willebrand Disease, Platelet Type	DisGeNET Gene-Disease Associations	1.0	null
Abductor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.701
PSPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17234
NCIH1341	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45579
RXRA::VDR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6
Reservosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.635
PK-15 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.516
EPS8L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55221
GTEX-VJYA-1126-SM-3GIJU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970563
ARFGEF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87184
ITGB3BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09375
hemophagocytic lymphohistiocytosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.448441
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12333
PCNX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41109
GSE169152_3_v_1_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
KYSE-520	COSMIC Cell Line Gene Mutation Profiles	1.0	null
colon cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.294413
NCIH650	CCLE Cell Line Gene CNV Profiles	1.0	2.17171
ITGA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31226
SAFB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86909
NFE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27948
carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.300894
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4619-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPN-0011-R7A-SM-2I5FI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23292
GTEX-NL3H-0011-R1a-SM-48TDJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945656
CRCGN017_MCF10A.WT.HP_24H:P15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15043
C5orf22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88778
MAPK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63748
Lung adenocarcinoma_LUAD_TCGA-55-6985-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FBXO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98298
GTEX-XQ3S-1526-SM-4BOOC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94748
CEBPB-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
uterine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.076341
gastric mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.186785
OCUM1	DepMap CRISPR Gene Dependency	1.0	3.39345
GTEX-T2IS-0126-SM-4DM6O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851149
SRSF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06007
TNNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15955
nerve	GTEx Tissue Gene Expression Profiles	1.0	0.864973
LSS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25209
MRPS34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54552
Regio parietalis capitis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.506
pancreatic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.292616
ATP5F1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46715
Congenital Bleeding Disorder	DisGeNET Gene-Disease Associations	1.0	null
MEOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80627
carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057739
chr12_11390525_C_A_b38	GTEx eQTL 2025	1.0	1.40614
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7143
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.7752
MCRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31524
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.388538
STX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58748
JIMT1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57669
AGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34029
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04362
Brain Lower Grade Glioma_LGG_TCGA-HT-7874-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PEA15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67979
PRDM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38787
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4645
CRCGN013_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.54741
ZNF625	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76967
Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3777-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Endotoxemia	DisGeNET Gene-Phenotype Associations	1.0	null
HELA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LAMA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12232
PCDHB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61382
CRCGN011_HEPG2_24H:M23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.32722
CES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87037
GTF3C3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38136
MCRIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52296
NO-10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.34
Acute Myeloid Leukemia_LAML_TCGA-AB-2967-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-BI-A0VS-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.31282
mouth	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-NPJ7-0011-R4a-SM-2I3GJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937456
cingulate gyrus, retrosplenial part, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.9321
GTEX-R55E-0126-SM-2TC5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04341
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7131
skin	GTEx Tissue Gene Expression Profiles	1.0	1.20544
GABPA	ENCODE Transcription Factor Targets	1.0	null
cuneus, left, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.37466
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.970819
GSE111247_0_v_13_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H4	DepMap CRISPR Gene Dependency	1.0	2.25541
Brain Lower Grade Glioma_LGG_TCGA-WY-A859-01A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C6orf120	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39932
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
intestinal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.104218
PMC8766486-42003_2021_2990_MOESM3_ESM.xlsx-ST18-Supplementary_Data_18_Gene_burden_for_deletions_by_subtype_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
SEC24B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76127
COPG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69726
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07902
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053291
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.837851
cingulate gyrus, parietal part, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.850037
GSE111247_11_v_3_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
INA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.80962
STK25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79896
HH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GAREM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1912
H3K9me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
MAGI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58319
496100327_PCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.97527
HYLS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30153
DCTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63425
Newcastle disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.293
MMUT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83024
GTEX-UPK5-0426-SM-3GAEK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17993
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
JHH-7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GPRC5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50798
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901033
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.9977
extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
exocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.81774
GTEX-XOTO-0126-SM-4B66N	GTEx Tissue Sample Gene Expression Profiles	1.0	2.05649
VPS4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39018
ANKRD65	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91072
TNNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50425
abnormality of the pancreas	GWASdb SNP-Phenotype Associations	1.0	0.424122
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850106
GTEX-XAJ8-0826-SM-47JY6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24039
Anaplastic large cell lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.749
Acute Myeloid Leukemia_LAML_TCGA-AB-2975-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7101
ALL-PO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044597
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893164
CCT6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29895
GTEX-RU72-0011-R7A-SM-2TF5U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856246
YME1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10654
HIPK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.31477
colon carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.204923
CTCF-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2966-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.846366
RPE1SS48	DepMap CRISPR Gene Dependency	1.0	2.62425
SOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67865
medial geniculate complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.934832
Lung adenocarcinoma_LUAD_TCGA-55-8512-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MKS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41123
SKN-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-7698-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MZT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74508
GTEX-TSE9-0011-R7A-SM-3DB7P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21182
neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.060844
CRCGN017_MCF10A.WT.HP_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.8213
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5263-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Alanine aminotransferase levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.20969
Brain Lower Grade Glioma_LGG_TCGA-HT-8558-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-N7MS-0011-R1a-SM-2HMJG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856157
Curli	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.642
ZNF808	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05247
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.49685
urinary bladder cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.137213
SW954	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.911
TMTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07501
CD320	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99887
T47D	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43766
GTEX-WVLH-3026-SM-3MJG9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944365
pancreatic adenocarcinoma	GWASdb SNP-Phenotype Associations	1.0	1.04365
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.129
HCC1359	DepMap CRISPR Gene Dependency	1.0	2.15534
Perturb_14752_KO_H3F3A_SRP252213	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.64106
Ovarian Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Plastid thylakoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.983
RASGEF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.98537
TAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80961
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12333
SK-MEL-24	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2954-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE213650_0_v_1_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF157	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98424
GTEX-QMR6-0011-R6A-SM-32PKP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24715
paracentral lobule, anterior part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11264
GTEX-U8XE-0326-SM-3DB8P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1509
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DELANZOMIB	DGIdb Drug Targets 2026	1.0	7.56171
AP4M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55309
NCI-H2141	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DNAJB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16232
NCIH1155	CCLE Cell Line Gene CNV Profiles	1.0	2.26179
NCI-H835	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ESYT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56454
GTEX-OXRN-0011-R5A-SM-2I5EF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03694
GSE184892_4_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC1419	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KMS-28BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2944
SK-MEL-28	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FSCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19424
NCI-H2110	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XOTO-0011-R7B-SM-4B64R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20547
ABRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22944
CRCGN011_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.35543
DG-75	COSMIC Cell Line Gene Mutation Profiles	1.0	null
large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.074487
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1962
FOXA1-21572438-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-OHPN-0011-R5A-SM-2I5FF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48155
GTEX-NL3H-0011-R3a-SM-2I3GL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978729
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986263
RBPMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8037
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5982
Kasumi-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.754
FAM117B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8026
SJRH30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF300	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90116
myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.055048
HNRNPCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8947
RAJI cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.692
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.24702
PFDN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46146
ARFIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23625
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065569
A375	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE233679_14_v_8_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Eyespot apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.56
prb2p130	GeneRIF Biological Term Annotations	1.0	null
Pneumonia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9969
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.58161
GTEX-SNOS-1126-SM-4DM67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40043
GTEX-N7MT-0011-R5a-SM-2I3G6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3441
PDIA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4079
GTEX-Q2AG-0126-SM-33HBV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13492
HES7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51707
Skin Cutaneous Melanoma_SKCM_TCGA-GF-A6C9-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.23
ITGA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97667
94T778	DepMap CRISPR Gene Dependency	1.0	2.49631
YT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-T5JC-0011-R7A-SM-32PME	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03038
CCNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60058
GTEX-TSE9-0011-R5A-SM-3DB7J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40987
GTEX-NPJ8-0011-R6a-SM-2HMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2384
Survival in pancreatic cancer	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.6
RPS25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3174
GTEX-XLM4-0011-R6A-SM-4AT4B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41508
NAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12169
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49059
KREMEN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25335
SCARA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81011
647-V	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE236502_2_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EB2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51081
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882548
GNG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02421
cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.187415
GTEX-S95S-1226-SM-4GICG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07945
precuneus, left, inferior lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.975893
OV7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78134
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.313552
GTEX-WWYW-3126-SM-3NB39	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869224
BRME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57963
HG3	DepMap CRISPR Gene Dependency	1.0	3.19571
Cholera	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.378
RAB2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46453
Kidney Chromophobe_KICH_TCGA-KN-8430-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A8OC-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ASXL1	ChEA Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YY-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TDGF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6776
NCIH1755	CCLE Cell Line Gene CNV Profiles	-1.0	-1.83921
IRF2BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4221
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Rootlet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.986
ITGA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7327
ELF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92723
Planktonic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.801
GTEX-QVUS-2826-SM-3GADB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852041
ANKRD30A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35754
MYO5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91349
GTEX-N7MS-0011-R10A-SM-2HMJK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858754
GSE213650_3_v_2_everolimus_human	RummaGEO Drug Perturbation Signatures	-1.0	null
P12-ICHIKAWA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6037
Saliva	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC8684775-CTM2-11-e640-s002.xlsx-Sheet1-Table_S3_MAF_file_of_the_CCS_samples_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
Lewy body-like hyaline inclusion	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.712
FOXI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52635
CCM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16061
Anaplastic large cell lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.692
DPY19L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53082
NCIH1651	CCLE Cell Line Gene CNV Profiles	-1.0	-1.92457
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.846952
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.80265
PRM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91129
chitin-based extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.249
endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.053089
GTEX-WWYW-0011-R1A-SM-3TW8G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02756
GTEX-WL46-0011-R7A-SM-3LK7X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1308
RPE1SS6	DepMap CRISPR Gene Dependency	1.0	2.09164
DAB2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84903
HIGD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03922
muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.054609
angular gyrus, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.93857
Rectum adenocarcinoma_READ_TCGA-F5-6812-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.WT.HP_24H:D20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24021
ARL6IP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6275
LONP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51743
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42988
SUPT1	DepMap CRISPR Gene Dependency	1.0	3.78054
RXF393	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Wax gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.922
GTEX-X585-0011-R6A-SM-46MVJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97507
CERS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2097
GTEX-XOTO-0011-R6B-SM-4B65X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08871
Efflux pump complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.439
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0671
HEG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88654
GADD45B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1655
CRCGN014_HEPG2_24H:M01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06047
AURKAIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37181
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19419
FAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27296
FAM124B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49374
SU-DHL-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18408
GTEX-N7MS-0011-R7a-SM-2HMKN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0948
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.933784
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1757
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.009
Chromosome passenger complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.057
SREBF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8847
PLCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36402
NCIH1373	CCLE Cell Line Gene CNV Profiles	1.0	1.52931
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842848
MIEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89397
Dental caries	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.214
Endocuticle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.73
SUPV3L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24693
ZMYM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80734
TSN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96735
gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045686
GTEX-WL46-0011-R2A-SM-3LK6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11968
RCH-ACV	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MBIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1744
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.43
GATAD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65653
SETD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34771
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12274
Type IV pilus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.698
ZSWIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43612
ZNF251	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48074
PTGES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97019
ZNF529	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3817
GTEX-PVOW-0126-SM-2XCFA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15667
MDBK cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.888
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.485
LHX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6262
SHISA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.432
PMC12381255-41389_2025_576_MOESM3_ESM.xlsx-Differentiated_SRCAP-1879-Gene_SRCAP	Rummagene Transcription Factor Associations 2026	1.0	null
NUGC2	CCLE Cell Line Gene CNV Profiles	1.0	1.57165
GTEX-V1D1-2026-SM-3GAF4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10509
paracentral lobule, posterior part, left, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.946887
RAB42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35251
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65988
TMEM25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28275
saliva	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.20778
HINFP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.318
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73G-01A-22R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.3764
RASGRP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0951
BLTP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40252
Acute Myeloid Leukemia_LAML_TCGA-AB-2897-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WWYW-0011-R10A-SM-3NB35	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955366
TIGD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39834
GSE146687_2_v_1_eribulin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7101-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2BC15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07314
GTEX-RVPU-0011-R10A-SM-2XCAH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94006
MROH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.77788
Acute Myeloid Leukemia_LAML_TCGA-AB-2803-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE221577_4_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Plantlet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.871
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.320591
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977767
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058619
CYBA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64775
MMP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88593
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053976
RPRD1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33586
GEMCITABINE	DGIdb Drug Targets 2026	1.0	0.186709
MRPS33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93429
NCIH2030	DepMap CRISPR Gene Dependency	1.0	2.65895
PMC9380317-13045_2022_1327_MOESM3_ESM.xlsx-Table_S4-Table_S4_Top_500_differentially_modified_gene_bodies_between_AA_and_EA_patients_with_MM_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.911736
GSE111247_2_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Epidural abscess	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.203
SRY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.31332
ENKD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01113
NARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60528
GSE111247_11_v_10_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T2IS-3026-SM-32QPM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833904
Mesocotyl	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.581
MTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61078
hsa-miR-4639-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
CHP134	DepMap CRISPR Gene Dependency	1.0	2.03148
E2F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55058
TE-10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SJSA-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GABRE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02719
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51024
Clathrin adaptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.166
endometrial carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.272953
ABHD15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40333
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.4908
POLL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.25083
PITRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76867
GTEX-T5JC-0011-R5A-SM-32PLK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24188
CTCF	ENCODE Transcription Factor Targets	1.0	null
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.566
Prostate adenocarcinoma_PRAD_TCGA-J9-A8CL-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
peroxisome	LOCATE Predicted Protein Localization Annotations	1.0	null
PMEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62514
GTEX-RVPU-0011-R7A-SM-2XCAB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869219
TAF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33434
Ichthyosis	DisGeNET Gene-Disease Associations	1.0	null
GARRE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81802
bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.340019
SK-GT-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HOXD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61483
paracentral lobule, posterior part, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.20538
CRCGN014_HEPG2_3H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.07808
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059979
Head	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	3.602
Methyl accepting chemotaxis protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.998
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.043
FAM76A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73724
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8403
lymphatic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.063147
musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043429
HT1080	DepMap CRISPR Gene Dependency	1.0	2.88192
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5982
H4C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30562
hypoglossal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.831004
promoter	GeneRIF Biological Term Annotations	1.0	null
CRCGN009_HEPG2_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05406
MLLT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68751
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.439507
PPARD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19772
CRCGN015_MCF10A.WT.HP_24H:M03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00399
NCIH1838	CCLE Cell Line Gene CNV Profiles	1.0	1.3278
ZNF549	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.932
MRPS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73969
EHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90618
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879132
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01172
ZNF430	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50475
DNASE1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57017
Hydrogenosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.034
RNF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28894
CRCGN008_HEPG2_24H:M12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01832
PHKA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48959
WDR20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18246
PHF5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60161
PMC8000424__F5	PFOCR Pathway Figure Associations 2024	1.0	null
Ventriculus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.756
CCZ1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68438
EGR3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.7715
TRIM17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18328
Drug-Induced Immune Thrombocytopenia	DisGeNET Gene-Disease Associations	1.0	null
RBPMS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94237
Tooth enamel	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.334
MEWO	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.36169
large cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.669936
YAMATO	DepMap CRISPR Gene Dependency	1.0	2.28525
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPM-0126-SM-2YUN9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0325
colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.108345
LMBRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87378
Dentine erosion	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.271
Type II site-specific deoxyribonuclease complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.791
Signal peptidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.0
LARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04288
BNIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3401
i-AAA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.59
Liver Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
FBXO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.16476
Brain Lower Grade Glioma_LGG_TCGA-HT-8113-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAFAH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60605
Salivary gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.735
GTEX-QMR6-0011-R7A-SM-32PKL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97886
IMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2614
Exocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	3.602
FBXW4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43182
GTEX-O5YW-0126-SM-3LK6D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873913
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29684
TMEM102	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96744
PWWP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60301
UMC-11	COSMIC Cell Line Gene CNV Profiles	1.0	2.10992
GDM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.029485
DPRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58998
BTBD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70752
PRDX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48561
SF3A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86295
GTEX-X261-0011-R5A-SM-3NMB4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09328
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
COQ9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43007
CRCGN017_MCF10A.WT.HP_24H:P09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.308
African Burkitt'S Lymphoma	DisGeNET Gene-Disease Associations	1.0	null
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5442
ZBTB48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29229
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.24539
uterus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057841
Human Immunodeficiency Virus	DisGeNET Gene-Disease Associations	1.0	null
Primary Malignant Neoplasm Of Lung	DisGeNET Gene-Disease Associations	1.0	null
VPS37A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35111
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00294
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.61372
TMEM258	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29118
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.912643
MIS18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22488
GTEX-X4XX-0011-R10B-SM-46MWO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1494
SYDE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18305
CRCGN011_HEPG2_24H:I02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11217
COLGALT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8327
FOXH1-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Phellem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.134
Campylobacteriosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
CRCGN014_HEPG2_3H:H21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00716
GTEX-NPJ8-0011-R5a-SM-2HMJY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16493
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YU-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FMO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.86776
PRDM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29046
UQCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37888
STK16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39066
CTAGE9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42332
ERVV-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59751
MAML1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19806
GTEX-NL4W-0011-R5a-SM-2I3GD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43094
CNOT6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51237
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57247
CRCGN012_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.00932
salivary gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HT3	DepMap CRISPR Gene Dependency	1.0	2.35117
SAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08863
ovary cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.218186
SUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43833
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.3653
olfactory tubercle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.31243
microbody	LOCATE Predicted Protein Localization Annotations	1.0	null
NEK8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93589
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9561
TRO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4896
HDMYZ	CCLE Cell Line Gene CNV Profiles	-1.0	-2.26107
GTEX-OHPN-0011-R1A-SM-2I5GB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15659
Giant cell reparative granuloma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.239
PLPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21993
CAMKV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26062
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.07975
COGAR359	DepMap CRISPR Gene Dependency	1.0	2.79086
jvm2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.922
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8046-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEYA8	DepMap CRISPR Gene Dependency	1.0	2.12692
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.520435
Phrenic nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.536
PSIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90579
PRRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82013
TBL1-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06491
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05385
Type IV secretion system complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.801
CREBBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30069
Neoplasm Metastasis	DisGeNET Gene-Phenotype Associations	1.0	null
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-12q13_11_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
FBXL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88016
POLR3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10486
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29618
HNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44476
Acute Myeloid Leukemia_LAML_TCGA-AB-2895-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GPR173	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59446
TRIM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.76995
GTEX-X4XY-0226-SM-4E3IZ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.3153
AtT-20 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.537
TMC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19166
CACTIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78128
hypertrophic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.375179
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
gl1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.53
GTEX-XK95-0226-SM-4AT58	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01767
GTEX-UTHO-0011-R5A-SM-3GIJD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921352
GTEX-S7PM-0126-SM-4AD6S	GTEx Tissue Sample Gene Expression Profiles	1.0	2.47673
LN-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-U3ZM-1526-SM-3DB9D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855992
RBM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43605
GTEX-X261-0011-R10B-SM-4E3JT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15997
Gingival disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.261
CRCGN016_MCF10A.TP53.M_24H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.02731
MAGEB17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42601
GCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06079
ASPC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68032
KHK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44642
COV413A	DepMap CRISPR Gene Dependency	1.0	2.04612
Plastid thylakoid membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.845
TLCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2262
posterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.928698
Mesothelioma_MESO_TCGA-NQ-A57I-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C15orf40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13896
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
LONRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31427
TMEM109	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33455
Buccal epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.779
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.133
PMC12304111-41598_2025_13196_MOESM5_ESM.xlsx-Sheet_1-Table_S4_DEGs_Log2FC_1_and_p_adj_0_05_in_pancreatic_cancer_with_high_versus_low_OVOL1_expression_OVOL1	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WI-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Squamous Cell Carcinoma Of Esophagus	DisGeNET Gene-Disease Associations	1.0	null
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.234
UNC13B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63555
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Tonsil	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.567
GSE111247_0_v_8_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
JHU-022	COSMIC Cell Line Gene Mutation Profiles	1.0	null
M059K	CCLE Cell Line Gene CNV Profiles	-1.0	-1.485
BB30-HNC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC9643473-Table1.xls-MAF_0_005-Gene_refGenecanonical_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
Periderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.077
small intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.076226
BLOC1S3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63827
DNMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85424
CRCGN014_HEPG2_24H:A03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.57454
TKFC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45916
YTHDF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77265
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.522011
SMOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61324
CGN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36184
G402	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32226
GTEX-X585-3026-SM-46MWF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38645
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46D-01A-21R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBE2J1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39049
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.540188
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.407
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1778
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
SQLE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02354
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.224
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31541
Bernard-Soulier Syndrome	DisGeNET Gene-Disease Associations	1.0	null
TUFM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24461
ZXDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34383
SGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32608
studies	GeneRIF Biological Term Annotations	1.0	null
RPL29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15908
Brain Lower Grade Glioma_LGG_TCGA-DU-A6S3-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cancer	GWASdb SNP-Disease Associations	1.0	0.050321
callus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.475034
GTEX-NPJ7-0011-R5a-SM-33HBK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19897
GSE123734_1_v_0_mien1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
tkts13	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.049
KLHL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87587
VCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0575
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945314
PDLIM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59669
ANKLE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04397
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
SPG21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19667
639V	CCLE Cell Line Gene CNV Profiles	1.0	1.32994
MAMSTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80731
Lung squamous cell carcinoma_LUSC_TCGA-39-5024-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84611
TRAPP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.701
Mesothelioma_MESO_TCGA-NQ-A638-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2669
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.978417
TAF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59862
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.3755
GTEX-Q2AH-1626-SM-3GAF8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910192
NAMALWA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z2-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
milker's nodule	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.144
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21859
Bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.378
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.025
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23837
ZNF74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31935
OAW-42	COSMIC Cell Line Gene Mutation Profiles	1.0	null
endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.197099
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.964604
TXK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41458
pelvis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.427254
HEC-1-A cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.676
TEX13B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.02172
NCI-H1694	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IALM	CCLE Cell Line Gene CNV Profiles	1.0	2.05067
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.846952
TCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1464
transitional cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.388538
THOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11415
GTEX-UTHO-0011-R3A-SM-3GIK8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860104
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056316
LITAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85597
PHF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97412
POU2F2	JASPAR Predicted Transcription Factor Targets	1.0	null
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_33_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
RBM4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79558
RH4	DepMap CRISPR Gene Dependency	1.0	2.63492
GSE233679_12_v_9_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF354C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33716
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.914109
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0017
CRCGN015_HEPG2_48H:F04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2204
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885127
saliva	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Clathrin coat of coated pit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.077
hsa-miR-579	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GTEX-X585-0011-R3B-SM-46MVG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41714
ALG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64845
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JVE015	DepMap CRISPR Gene Dependency	1.0	2.72931
KIF3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72413
RCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44917
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03793
Pellicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.82
Lung squamous cell carcinoma_LUSC_TCGA-77-7141-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.58557
NCI-H2172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.870925
salivary gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.844545
Influenza	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.267
Response to gemcitabine in pancreatic cancer	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.6
GTEX-X4XX-0011-R3B-SM-46MWK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10177
GTEX-QDT8-0011-R6A-SM-32PKI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824922
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52086
SQ1	CCLE Cell Line Gene CNV Profiles	1.0	1.61871
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8169
NCI-H650	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ovary adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.331927
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.858764
LEPROTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04286
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053277
PAX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50849
SUM229PE	DepMap CRISPR Gene Dependency	1.0	3.65695
Accessory sex gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.131
SLR26	DepMap CRISPR Gene Dependency	1.0	2.63985
inferior occipital gyrus, left, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.824469
ZNF610	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44176
MEL290	DepMap CRISPR Gene Dependency	1.0	2.66054
PABPC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.64871
ST6GAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81878
CRCGN013_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04327
GTEX-WWYW-0011-R6A-SM-3NB3G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18439
GTF2H4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38118
Uterine Carcinosarcoma_UCS_TCGA-NA-A5I1-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Periodontitis (CDC/AAP)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.504576
PMC6951973__F5	PFOCR Pathway Figure Associations 2023	1.0	null
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7395
Lung squamous cell carcinoma_LUSC_TCGA-21-1076-01A-01R-0692-07,TCGA-21-1076-01A-02R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NDEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84851
neoplasm by anatomical site	GWASdb SNP-Phenotype Associations	1.0	0.063239
TRDMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24074
ZNF611	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27981
UMUC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34383
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5083-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	102.438
EPN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24769
C9orf40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15602
H2BC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77795
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
Periurethral tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.668
Placental membrane	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.731
Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MON1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0845
NLRP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50221
GTEX-N7MT-0011-R7a-SM-2I3FZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30503
Dental plaque	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.925
CRIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18838
RADX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30539
BL2287 (ZC3H13)	NURSA Protein Complexes	1.0	null
RL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.913661
ENOPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72579
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054134
OAZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55022
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059012
CRCGN012_HEPG2_24H:H03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06741
FUNDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05659
RAB5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92439
CHD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79493
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.22003
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.11
Paracoccidioidomycosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.042
TLNRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37838
GTEX-S7SE-0011-R5A-SM-2XCDA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35277
SSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55587
reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045314
MERO83	DepMap CRISPR Gene Dependency	1.0	2.23255
ASH-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HuH-7-Lunet cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.989
Brain Lower Grade Glioma_LGG_TCGA-HT-7694-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2248
Actinobacillosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.427
NCI-H1155	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.978417
EPPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7226
33B cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.815
GTEX-QVUS-0011-R6A-SM-3GACX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925456
GTEX-PWO3-0926-SM-2I5EY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00717
GTEX-S32W-2126-SM-2XCB1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947899
GSE192870_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRABP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42353
hsa-miR-616	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
SH4	CCLE Cell Line Gene CNV Profiles	1.0	1.41068
Thrombocytopenia	DisGeNET Gene-Phenotype Associations	1.0	null
SFMBT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1161
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.378514
EZH2	ENCODE Transcription Factor Targets	1.0	null
JM1	DepMap CRISPR Gene Dependency	1.0	3.08571
MUTZ8	DepMap CRISPR Gene Dependency	1.0	2.20754
GTEX-XOTO-0726-SM-4B659	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78214
TLR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18674
AP1M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25248
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
PMC12126244-jci-135-184115-s239.xlsx-Table_3_Suppl_Fig_16-Genes_down-regulated_in_SOX9_low_tumors_744_genes_SOX9	Rummagene Transcription Factor Associations 2026	1.0	null
496100438_PCx_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.00411
NPAS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45693
SPI1	ChEA Transcription Factor Targets	1.0	null
endocrine gland cancer	GWASdb SNP-Disease Associations	1.0	0.438494
SNU2535	DepMap CRISPR Gene Dependency	1.0	2.38539
GTEX-S7SE-0126-SM-2XCD5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48512
intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.060174
Submandibular gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.286
transverse gyri, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.855864
Ovarian Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
NDUFA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91832
SKMEL1	CCLE Cell Line Gene CNV Profiles	1.0	1.68268
G-401	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-5128-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Thylakoid membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.705
NFKBIZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4715
USP13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52277
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.1079
PLXNA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7706
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872308
DUSP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49197
urinary bladder cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.539
Cpa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.079
Epimastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.79
CRCGN017_MCF10A.WT.HP_24H:P08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.64507
RARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56639
neoplasm of the pancreas	GWASdb SNP-Phenotype Associations	1.0	1.04365
496100337_HIP_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.59031
Coronavirus infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.379
MASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9051
GCIY	CCLE Cell Line Gene CNV Profiles	1.0	1.34709
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.858764
Childhood Neuroblastoma	DisGeNET Gene-Disease Associations	1.0	null
GTEX-RU72-0011-R5A-SM-2TF6U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4524
H2869	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
VPS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54107
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IQ-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.442
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.238406
pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.159838
periodontal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.112636
PHLDA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59752
PELP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90393
Avian influenza	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.537
BHMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9015
IGR-37	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pilus shaft	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.522
UACC-812	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ATP-dependent citrate lyase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.639
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.13
SPI1-23547873-NB4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-QVJO-1426-SM-2S1QY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970345
Lung adenocarcinoma_LUAD_TCGA-05-4403-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KARPAS-422	COSMIC Cell Line Gene Mutation Profiles	1.0	null
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053963
Hepatitis C	DisGeNET Gene-Disease Associations	1.0	null
PAGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95734
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.969961
RPMI-7951	COSMIC Cell Line Gene Mutation Profiles	1.0	null
pancreatic cancer	GWASdb SNP-Disease Associations	1.0	1.19386
BL2293 (EDC4)	NURSA Protein Complexes	1.0	null
MYADM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19073
SKA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32396
ABHD17A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17556
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22391
GTEX-N7MS-0011-R5a-SM-2HMK8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17935
TCL1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6009
GTEX-WHSE-0011-R7A-SM-3P5YZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34141
ZBTB39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43231
bind	GeneRIF Biological Term Annotations	1.0	null
HAUS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48106
CPSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92679
FOXF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47277
Saliva	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.927
ZFP36L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55757
PPM1J	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74689
NACA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78296
GTEX-WHSE-0011-R6A-SM-3P5ZP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23428
PTPN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07299
Retinoblastoma	DisGeNET Gene-Disease Associations	1.0	null
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.891384
MM1S	COSMIC Cell Line Gene Mutation Profiles	1.0	null
C12orf4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54344
GTEX-WVLH-0011-R6A-SM-3MJFZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35504
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2374
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28151
RASAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4037
Conjunctivitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.19
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7055-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superior parietal lobule, left, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.829518
SPO11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12058
GTEX-WWYW-0011-R7A-SM-3NB3H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88489
ERF::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.1933
superior occipital gyrus, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.845374
KCI-MOH1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1512
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0473
GTEX-T6MN-2626-SM-32PMQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07718
MRPL37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52868
FLII	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16954
KDM3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19628
ARHGEF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59209
PPTC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01161
E2F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9941
496100340_TCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.06987
PMC8497275-41388_2021_1985_MOESM9_ESM.xlsx-ER_targets_ER-SRC3-RAC1_sites-Nearest_Ensembl_NCOA3	Rummagene Transcription Factor Associations 2026	1.0	null
SRD5A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02544
MFE-280	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65833
PRPF39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9343
GTEX-XLM4-0011-R3B-SM-4AT6E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879641
XKR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01952
RPAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82686
Leukopenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
GTEX-XOTO-0011-R5A-SM-4B657	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11619
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
PMC10794847-mmc5.xlsx-PIAS1_KD_up-Table_S4_Differentially_expressed_genes_with_PIAS1_knockdown_in_the_progenitors_state_Related_to_Figure_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
COX7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97754
GTEX-QEG4-0226-SM-2S1PY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37858
PRKX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28497
RWDD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37059
Sporozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.724
BCL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11524
USP19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85239
SMG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50819
STK36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.96753
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PIAS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54088
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.49497
GTEX-QESD-1426-SM-2S1R9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933781
GTEX-RNOR-2326-SM-2TF4I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955978
CERCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31329
Lung adenocarcinoma_LUAD_TCGA-78-7540-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tooth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.073829
NT5DC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.68638
ovary cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.088034
GSE95302_1_v_4_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
MDCK-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.599
SNX11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76945
LMAN2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20448
Biofilm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.143
D341Med	DepMap CRISPR Gene Dependency	1.0	3.44476
Small Intestine - Terminal Ileum	GTEx Tissue Gene Expression Profiles 2023	1.0	3.17272
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.996
AP-2 adaptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.078
S100A14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95286
KURAMOCHI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
INAFM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7735
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835389
DDX19B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27055
AGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20013
Amoebocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.661
CRCGN011_HEPG2_24H:J13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.243
PDCD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00549
FBXO31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.42641
SOX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49299
skov-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.395331
molaris	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.449116
RAB29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51244
MEPCE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47188
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07902
ARHGAP19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80795
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1199
KMRC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	3.602
chr12_11421576_C_T_b38	GTEx eQTL 2025	1.0	1.39831
occupancy	GeneRIF Biological Term Annotations	1.0	null
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48702
Central Neuroblastoma	DisGeNET Gene-Disease Associations	1.0	null
ATG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05753
GSE231745_1_v_0_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
JMURTK2	DepMap CRISPR Gene Dependency	1.0	3.87785
H3K27me3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TNFAIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31252
myometrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.261964
Normoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.025
Hemorrhagic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.005
GTEX-QVJO-1626-SM-2S1QW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01057
Adrenocortical carcinoma_ACC_TCGA-OR-A5JD-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF780B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69953
RPS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40092
HCC1897	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56269
gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.184128
Hyphal cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.502
CFAP68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57331
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6324-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JOPACA1	DepMap CRISPR Gene Dependency	1.0	2.21343
CARFILZOMIB	DGIdb Drug Targets 2026	1.0	0.126029
MADD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20274
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-7631-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.60103
Buccal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.654
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80K-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-96-7544-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070661
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.93061
AP-type membrane coat adaptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.159
icSARS CoV_7Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.77043
IA-LM	COSMIC Cell Line Gene CNV Profiles	1.0	2.10992
hsa-miR-4670-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Carcinoma Of Lung	DisGeNET Gene-Disease Associations	1.0	null
Secondary Malignant Neoplasm Of Liver	DisGeNET Gene-Disease Associations	1.0	null
APEX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06455
RHEBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35035
RH18	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75997
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043091
STAG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54334
MFE-296	COSMIC Cell Line Gene Mutation Profiles	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
OV7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.90364
Plant epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.652
RFXAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51162
brain	GTEx Tissue Gene Expression Profiles	1.0	2.14415
Invasive aspergillosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
GTEX-PVOW-0011-R5A-SM-32PL7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24306
ENTPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26604
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837027
Photosystem II oxygen evolving complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.638
DDHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37424
ZNF133	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47282
GSE111247_0_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
X	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08702
GTEX-X4XX-0011-R8B-SM-46MWM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940935
occipito-temporal gyrus, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12305
GTEX-R55G-2526-SM-2TC6D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936259
ARID3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33191
MED12L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.3298
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05974
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12826982-mmc5.xlsx-Table_S4-Supplementary_Table_S4_Differentially_Bound_Down-regulated_Peak-Related_Genes_in_Flag-SOX3-HSV-1_vs_Flag-SOX3-Mock_SOX3	Rummagene Transcription Factor Associations 2026	1.0	null
primary bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042799
PK-59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19419
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VE-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04382
ZDHHC19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77628
autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.050571
SEMA4F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88463
Diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.664
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.80265
NCI-H345	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-X88G-0126-SM-47JZ3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868643
UBE3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79864
disrupting	GeneRIF Biological Term Annotations	1.0	null
Exoskeleton	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.619
CD37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77802
lingual gyrus, left, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21794
PTPRCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33445
GTEX-T6MN-0126-SM-32PLP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976777
Retrotransposon nucleocapsid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.028
RCHACV	DepMap CRISPR Gene Dependency	1.0	3.58497
Nasal cavity	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.964
Perturb_15189_KD_TP63_SRP056637	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
clathrin-coated vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.087
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.36662
CALU-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IGROV-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.519
Endopeptidase Clp complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.231
LCN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03545
ac2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.663
PRDM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5303
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838562
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31449
GTEX-XOTO-3026-SM-4B65M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938005
exocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.28
CLPTM1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30391
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22282
SK-N-AS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.256228
t-24 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.640833
TYW5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20929
GTEX-XLM4-0011-R10A-SM-4AT5P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02031
NB-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S7PM-0011-R5A-SM-3NM8G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844687
Prostate adenocarcinoma_PRAD_TCGA-CH-5740-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-IH-A3EA-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OXRP-0126-SM-3NB32	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02527
CRCGN011_HEPG2_24H:C08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6596
EPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99321
muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.053799
GTEX-WHSE-0011-R1A-SM-3P5ZK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934971
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45901
dohh2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.856
Pancreatic Neoplasms	dbGAP Gene-Trait Associations	1.0	0.50084
CP50-MEL-B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MARCHF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15417
H3K27me3_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53325
GTEX-QVJO-0011-R5A-SM-2S1QM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53949
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.836
Bacterial biofilm matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.64
EPB41L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99914
NMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24946
PF382	DepMap CRISPR Gene Dependency	1.0	3.10146
MEWO	CCLE Cell Line Gene CNV Profiles	-1.0	-2.26928
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1835
TMEM44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83848
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0293
PADI4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40118
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00294
Gracilis muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.959
RAD54L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9535
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7432-11A-01R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tooth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.109036
VGF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67957
HNRNPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4969
Pancreatic adenocarcinoma_PAAD_TCGA-FB-A5VM-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHLPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1641
MORCPR	CCLE Cell Line Gene CNV Profiles	-1.0	-2.04062
TP73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22411
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
BTG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31316
TACC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31252
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1917
C9orf72	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51576
SNCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25335
HOP-62	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MAP2K1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38778
endometrial cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.095218
Sporadic Retinoblastoma	DisGeNET Gene-Disease Associations	1.0	null
ICC9	DepMap CRISPR Gene Dependency	1.0	2.25186
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043844
Macrothrombocytopenia	DisGeNET Gene-Disease Associations	1.0	null
TMED3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27661
X, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.908291
697	DepMap CRISPR Gene Dependency	1.0	3.85286
HAND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35932
EDARADD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60704
PKP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66828
Chloroplast thylakoid membrane protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.9
ZSWIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48172
PSII associated light-harvesting complex II	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.974
MAML3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88337
MAEA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37026
TP63	ChEA Transcription Factor Targets	1.0	null
TRAPPC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12427
carbamoyl-phosphate synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.947
Conjunctival disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.16
SSTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32588
GTEX-S7SE-0011-R1A-SM-2XCDE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14733
DMS-114	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TNKS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50383
STARD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24209
adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.17952
COG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93575
disease	GWASdb SNP-Disease Associations	1.0	0.026074
Salivary duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.966
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6428
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
REST	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.3431
RH-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Parasitic infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.164
TEX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18246
ENDOU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84522
VPS39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98919
Pulmonary artery endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.5
ZNF813	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42297
AIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9415
FSTL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07429
mouth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.060723
ASXL1-24218140-BMDM-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5108
GPATCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62383
PMC8423434-mmc7.xlsx-KLF4_HENSM-Genes_n_2172_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
KLHDC8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.534
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5491-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-51-4081-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X5EB-2226-SM-46MW4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09814
PES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10637
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3440-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MREG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80671
LOU-NH91	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49558
PROB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65775
GTEX-RNOR-0011-R7A-SM-2TF4V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02985
FUOV1	CCLE Cell Line Gene CNV Profiles	1.0	2.75202
CRCGN015_HEPG2_48H:E22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.18555
tail of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.71482
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.912643
CRCGN015_MCF10A.TP53.M_24H:O24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2808
HFL-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.686
putamen, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.16054
hsa-miR-944	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
ONECUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38701
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-S7PM-0011-R6A-SM-3NM8F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886287
GTEX-NL4W-0011-R6a-SM-2I3GA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50651
CENPJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62373
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.03855
H2AC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.43353
GSE111247_14_v_10_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-Q2AG-0011-R7A-SM-2HMJP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29317
IP6K1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61115
CAL-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NMI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90426
Parasitic protozoa infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.095
SOCS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38532
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.238
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6493
Cuticle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.254
MATR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7278
pancreatic cancer	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.256228
DDX23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23791
Cytostome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.179
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.910685
female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.162908
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056553
GTEX-OXRN-2426-SM-2I5EQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853357
GTEX-WVLH-0011-R2A-SM-3MJFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824561
GI1	DepMap CRISPR Gene Dependency	1.0	2.14166
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.910685
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.944556
NOTCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86416
Coronary Artery Disease	DisGeNET Gene-Disease Associations	1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04101
CREB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25618
Gingival fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.954
ZNF574	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.6723
GDI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41052
TARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07489
GTEX-T5JC-0011-R10A-SM-32PM2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02678
CBFA2T3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58171
RRP36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03985
HTR1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1147
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.846366
HslUV protease complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.476
EXOC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05015
altering	GeneRIF Biological Term Annotations	1.0	null
NFYA	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-TSE9-3026-SM-3DB76	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970714
CRCGN015_MCF10A_48H:F21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.00828
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52086
TRIM61	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38403
GTEX-N7MS-0011-R6a-SM-2HMJ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3121
CRCGN016_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.22965
PMC6951973__F5	PFOCR Pathway Figure Associations 2024	1.0	null
Refractory Thrombocytopenia	DisGeNET Gene-Disease Associations	1.0	null
methylation	GeneRIF Biological Term Annotations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8I8-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WASF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.60941
Subrhabdomeral cisterna	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.061
PRPF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28571
Brain Lower Grade Glioma_LGG_TCGA-F6-A8O4-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPP1R3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1194
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5EA-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Night sleep phenotypes	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.522185
COCH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98995
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UBA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72691
PXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59615
GTEX-WZTO-0011-R10B-SM-4E3KB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0646
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.871889
SMAD4-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TRIM62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36938
FYCO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98122
GTEX-NPJ7-0011-R10A-SM-2I3E5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11638
SMAD2/3-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SSX2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97577
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052562
OPROZOMIB	DGIdb Drug Targets 2026	1.0	1.26029
FAM171A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69833
GTEX-OXRO-0126-SM-2YUN4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07546
FANCE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06057
FUNDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83719
OS9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06578
PRCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08832
mouth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.841608
Photosystem II reaction center	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.517
SLC2A14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84957
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02438
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.847186
POLR2M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90446
PL4	COSMIC Cell Line Gene CNV Profiles	1.0	2.10992
NAP1L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13119
STK38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97623
Thrombasthenia	DisGeNET Gene-Disease Associations	1.0	null
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
NPTX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.488
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_1h-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
HUG1N	CCLE Cell Line Gene CNV Profiles	1.0	1.58705
CCDC80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06251
H2AC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41174
Brain Lower Grade Glioma_LGG_TCGA-HT-7880-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00512
EWS-ERG-20517297-CADO-ES1-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:D13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.28103
HOXC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28692
Urethral calculus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.077
Acute Myeloid Leukemia_LAML_TCGA-AB-2807-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sp95	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.973
CHGB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24325
GTEX-WZTO-0011-R5B-SM-3NMC5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4252
Brain Lower Grade Glioma_LGG_TCGA-FG-A713-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Allantoic fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.131
GPATCH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74828
Ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.604
SHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22173
urinary bladder cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.539396
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.36526
GTEX-WVLH-0011-R5A-SM-3MJFW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53891
Y79	DepMap CRISPR Gene Dependency	1.0	3.03515
Tou	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.952
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4847
GTEX-XBED-2226-SM-47JYQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931464
ZNF490	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35451
immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041776
GTEX-R55E-0011-R7A-SM-2TC5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891871
GTEX-PWO3-0011-R5A-SM-2I5EZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18887
NCIH441	DepMap CRISPR Gene Dependency	1.0	2.52462
Prostate adenocarcinoma_PRAD_TCGA-HC-7820-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WZTO-0126-SM-3NM95	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943996
UBE2R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36596
Sarcoma_SARC_TCGA-PC-A5DN-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PNLDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26141
Whole Blood	GTEx Tissue Gene Expression Profiles 2023	1.0	3.1961
LARP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45171
BHK-21 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.923
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10264
NHLRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20928
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05345
ZNF35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95296
Endocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.963
Gizzard	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.783
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M4-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PCDHB12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08163
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2248
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F4-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40652
K562	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58899
CNOT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64595
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.659
REH	DepMap CRISPR Gene Dependency	1.0	3.21545
HTR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9434
CCDC77	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38685
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1683
GTEX-NPJ7-0011-R6a-SM-2I3G7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54497
GTEX-RU72-0926-SM-2TF6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37298
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.378
XPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30082
ZNF837	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56669
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.412
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
PSI associated light-harvesting complex I	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.218
LDHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57969
MM127	DepMap CRISPR Gene Dependency	1.0	2.75908
inferior occipital gyrus, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.887407
fh4	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.586
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.846366
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7339
496100410_TCx_possible Alzheimer's disease_TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.16459
H2AC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.61338
heart	GTEx Tissue Gene Expression Profiles	-1.0	-1.08463
salivary gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01172
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3443-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.73755
SPI1-23547873-NB4-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
nucleus accumbens, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13677
GTEX-X4XX-0011-R1B-SM-3P622	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888916
FLAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58894
clathrin-coated endocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.071
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.846952
HICS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.678
CETN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77732
Lung squamous cell carcinoma_LUSC_TCGA-33-4538-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IGSF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9006
NBPF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75641
C1orf109	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31342
GTEX-QVJO-0011-R9A-SM-2S1QH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87882
PAX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61083
GTEX-N7MT-0011-R10A-SM-2I3E1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.974128
BTBD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08804
P300-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Malignant Transformation	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-X4XX-3026-SM-3NMB2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27308
SKMEL31	CCLE Cell Line Gene CNV Profiles	1.0	1.45155
ZC3H18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69648
ZNF665	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58943
T98G	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SISO	DepMap CRISPR Gene Dependency	1.0	2.14911
CHST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65147
Pancreatic Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
ES1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SUN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48509
GTEX-WK11-2726-SM-3NMAQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891348
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TG-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A5SO-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11B-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C16orf87	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01454
SNU1327	DepMap CRISPR Gene Dependency	1.0	2.22305
exocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05287
HDDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7225
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.20323
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE187006_3_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH1048	DepMap CRISPR Gene Dependency	1.0	2.52187
Breast Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
SBC-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TCFL5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4558
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5892
Sublingual gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.868
HUTU-80	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TBK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21574
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45815
H3C7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19464
NPPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09419
CCNE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56578
P31FUJ	DepMap CRISPR Gene Dependency	1.0	2.2171
kidney	GTEx Tissue Gene Expression Profiles	-1.0	-0.837478
CCDC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14621
FAM104B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95044
SCABER	CCLE Cell Line Gene CNV Profiles	1.0	1.42637
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9943
GTEX-QVJO-0011-R4A-SM-2S1QL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964458
GHITM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49951
FREM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45262
MRPL35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88123
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.335
TTYH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61055
VAPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3698
suggested	GeneRIF Biological Term Annotations	1.0	null
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7126
CASTOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17335
cholera	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.162306
HS2ST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69716
HIV-1_LAI_12Hour-UV_treatment_None_GSE56484	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.43182
CRCGN016_MCF10A.WT.HP_24H:E20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.38005
CLDN15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42653
HUT102	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7659
chromatin	GeneRIF Biological Term Annotations	1.0	null
LC-2-AD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
superior parietal lobule, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.85416
RAD51D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77718
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7434-11A-01R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042362
CRCGN015_HEPG2_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.07656
enterocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.23011
GSE236502_2_v_0_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SUIT2	CCLE Cell Line Gene CNV Profiles	1.0	1.96658
RPE1SS119	DepMap CRISPR Gene Dependency	1.0	3.04968
cyclin	GeneRIF Biological Term Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-5965-02B-11R-A29R-07,TCGA-FG-5965-02A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882357
SNAP29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05201
RMI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28648
Response to gemcitabine in pancreatic cancer 	GWAS Catalog SNP-Phenotype Associations	1.0	0.220915
NSA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25395
not applicable_asthma_GSE43696_369_mouse_bronchial epithelial cell	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
T84	COSMIC Cell Line Gene CNV Profiles	1.0	2.10992
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE233679_14_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Vegetative stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.846
NAGS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41101
PPP6R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24425
Middle frontal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.534
GTEX-T5JC-0011-R1A-SM-32PM6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905447
NCI-H650	COSMIC Cell Line Gene CNV Profiles	1.0	2.10992
Brain Lower Grade Glioma_LGG_TCGA-HT-8107-01A-13R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55E-0011-R5A-SM-2TC5N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01439
GTEX-WZTO-0011-R6B-SM-4E3J6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24055
UCHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5147
QDPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49538
dna	GeneRIF Biological Term Annotations	1.0	null
GTEX-X4XX-0011-R5A-SM-46MWN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995674
SEMA3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54402
ChaGo-K-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.743
Parotid gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.987
small intestine epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.181724
CRCGN008_HEPG2_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30652
ICAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89788
CCND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87272
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.910248
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.693
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-UPJH-0326-SM-3GADU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886842
GTEX-S3XE-1726-SM-3K2AM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33641
LAMA84	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34047
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15001
HS939-T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PCI-30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UBA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75001
ZNF101	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58361
GTEX-N7MT-0011-R6a-SM-2I3G3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52478
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.979901
Prostate adenocarcinoma_PRAD_TCGA-G9-7519-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SH10TC	CCLE Cell Line Gene CNV Profiles	1.0	1.65771
mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
ZNF669	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.185
GTEX-WFG8-1926-SM-4LVM1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886915
NCIH1781	CCLE Cell Line Gene CNV Profiles	-1.0	-2.8457
PREB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51965
NT5DC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22296
AGO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75566
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859089
LS1034	CCLE Cell Line Gene CNV Profiles	1.0	1.93731
FAU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36539
MAX::MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9524
LRRC55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76515
OCUB-M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SHQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62367
SU-DHL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.913661
PC-14 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.957
NTS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79227
TK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mucous gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.256234
PDIK1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39023
Radicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.203
CTCF-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
KDM4E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51274
CRCGN014_HEPG2_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.90564
Pleural mesothelioma	WikiPathways Pathways 2024	1.0	null
Leukocyte disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.201
CRCGN017_MCF10A.WT.HP_24H:O18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.22155
SLC16A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.42674
LN229	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44153
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947502
PJA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24272
monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043867
PTPRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04314
GTEX-WWYW-0011-R5A-SM-3NB3E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14373
OR2B6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85325
ZBTB43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74757
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.209
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.846952
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-0011-R5A-SM-3LK6V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20285
CEBPB	ENCODE Transcription Factor Targets	1.0	null
TOP2B-26459242-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
LIPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85294
Barrett's epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.04
intestinal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.236921
GTEX-QLQW-1126-SM-2S1Q8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12208
KYSE-450	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.847186
PMC7880998-41467_2021_21255_MOESM8_ESM.xlsx-Sup_Data_5_TWIST_Panel-Gene_Name_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
C8orf82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35718
Kidney Chromophobe_KICH_TCGA-KL-8323-01A-21R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
8505C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CDS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33844
METTL21C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55468
SUPM2	DepMap CRISPR Gene Dependency	1.0	3.95978
WDR76	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56202
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052878
IXAZOMIB CITRATE	DGIdb Drug Targets 2026	1.0	1.08024
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.247
H3C15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49622
STPG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34609
GTEX-X4XX-0011-R4B-SM-46MWL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858262
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.18629
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833888
RIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18347
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.945713
LBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36953
GTEX-Q2AG-0011-R6A-SM-2HML7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31841
ZNF575	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36957
Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZC3H13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78506
KMS27	DepMap CRISPR Gene Dependency	1.0	3.03667
Primary bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.224
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.964
CAL78	CCLE Cell Line Gene CNV Profiles	1.0	1.62181
Liver	GTEx Tissue Gene Expression Profiles 2023	1.0	3.94446
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833262
MPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20856
SK-OV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45901
PRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89043
SIN3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59345
Whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	3.602
Salivary secretion	KEGG Pathways 2026	1.0	null
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.089
cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.106788
WSU-DLCL2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
hdac1	GeneRIF Biological Term Annotations	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.056
GTEX-TMZS-0126-SM-3DB9Q	GTEx Tissue Sample Gene Expression Profiles	1.0	2.13194
cc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.03
GTEX-S7SE-0011-R6A-SM-2XCD9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24903
cancer	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.256228
bf34	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.046
RBM42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09717
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01777
CL-40	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.978417
IQSEC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02576
Vaginal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.586
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11C-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pseudolymphoma	DisGeNET Gene-Disease Associations	1.0	null
GTEX-X62O-0126-SM-4E3JN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78375
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1234
CRCGN011_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14452
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.436055
CRCGN015_MCF10A_48H:F02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.10753
PPFIA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66141
colonic mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.468048
HOXA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41382
PMC8452624-41467_2021_25709_MOESM12_ESM.xlsx-ST12-Unnamed_2_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE184892_0_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-Q2AG-0011-R5A-SM-2HMJH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30505
GTEX-RVPV-0011-R5A-SM-2TF69	GTEx Tissue Sample Gene Expression Profiles	1.0	1.448
Paragonimiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.417
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1486
ML-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MAT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71858
ANKRD49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76499
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8473
CRCGN008_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.20087
DPM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86726
NH-12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NPM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55266
Albedo	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.719
ATP13A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12512
NCI-H1623	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE111247_11_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4696-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:G19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25157
IFRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04157
SHOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94487
Spore wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.617
ARNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18932
THAP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89102
EB-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MEWO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.98583
TMEM169	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88272
ATP13A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36777
GSE169617_1_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MRPS17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87542
PIPOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6798
USF2	JASPAR Predicted Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4334-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Endometrial Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Microspore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.098
HH	CCLE Cell Line Gene CNV Profiles	1.0	1.54732
KLF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02344
Mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	3.602
Coelomocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.537
GSE111247_14_v_12_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
JADE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37872
GTEX-RVPU-0011-R5A-SM-2XCAD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29882
Childhood Osteosarcoma	DisGeNET Gene-Disease Associations	1.0	null
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874252
cuneate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.880248
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01389
EGR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.3566
GTEX-XOTO-0011-R3A-SM-4B64W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909491
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11486
prb2p130complexes	GeneRIF Biological Term Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3427-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2983-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UMC-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ATP2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23321
GTEX-NPJ8-1526-SM-2D7VU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04236
EARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00867
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890647
Mesothelioma	DisGeNET Gene-Disease Associations	1.0	null
HCC2279	CCLE Cell Line Gene CNV Profiles	1.0	1.69246
Kidney Chromophobe_KICH_TCGA-KN-8432-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CMTR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62756
GTEX-S7SE-0011-R7A-SM-2XCDI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33532
Clathrin coat of endocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.078
parotid gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.16693
DV-90	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.698
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	94.606
CRCGN017_MCF10A.WT.HP_24H:E16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02805
Brain Lower Grade Glioma_LGG_TCGA-FG-7643-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X585-0011-R4B-SM-46MVH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04482
Acute vascular insufficiency of intestine	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.401
RELCH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2816
Pancreatic adenocarcinoma_PAAD_TCGA-3E-AAAY-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pasteurellosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.013
Lung squamous cell carcinoma_LUSC_TCGA-85-7697-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.TP53.M_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14154
GTEX-QDT8-0011-R4A-SM-32PKM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885997
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.13693
Mouth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.152
CRCGN008_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.87348
EPHX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38867
colon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.507064
CRCGN016_MCF10A.TP53.M_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.79395
NCIH1666	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37386
HCC1143	CCLE Cell Line Gene CNV Profiles	-1.0	-2.66219
SCARF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30169
antropyloric mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.51335
TAF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04603
CCNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7535
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38044
ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.825268
Prostate adenocarcinoma_PRAD_TCGA-EJ-5519-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Carcinoma, Ovarian Epithelial	DisGeNET Gene-Disease Associations	1.0	null
ELP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84454
PLXND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50865
POLD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35854
GTEX-WVLH-0011-R7A-SM-3MJFB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09854
GNAZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50973
GSE160817_0_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
RPRD1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72365
e21	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.338
Body wall muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.914
TAF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.81763
GTEX-XLM4-3026-SM-4AT6L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919744
496100508_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07845
ARID4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81512
TRAPPC6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08408
TMEM9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28271
Clathrin vesicle coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.094
disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040093
pattern	GeneRIF Biological Term Annotations	1.0	null
SPEG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.74728
KYSE-30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE190864,GSE190907_1_v_0_cacybp_human	RummaGEO Gene Perturbation Signatures	1.0	null
MKN1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
head of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.61334
METTL17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3989
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.895961
CRCGN014_HEPG2_24H:I24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.63027
Brain Lower Grade Glioma_LGG_TCGA-DU-A6S2-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
colorectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.422292
TSPAN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02196
fh6	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.79
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_42_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
MS751	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.128
Lung abscess	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.014
CRCGN015_HEPG2_48H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.10954
ADGRL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71826
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21859
cuneus, left, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.958848
ASAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74936
AFTPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10443
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.275
IGROV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LN382	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34793
TMEM130	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50525
PCGF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.77389
Parotid gland duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.891
PROM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90418
GTEX-UTHO-0011-R6A-SM-3GIJW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13375
ln405	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.644
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
Ubiquinone biosynthesis complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.99
GTEX-OIZH-2126-SM-3NB1P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13251
GTEX-X4XX-0126-SM-3NMC2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22145
SK-6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.944
Lung squamous cell carcinoma_LUSC_TCGA-98-8020-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.029518
GTEX-NPJ8-0011-R7a-SM-2HMJV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877053
extracellular region	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-WHSE-3026-SM-3P5ZH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983068
ZNF284	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96833
SP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63992
GTEX-Q2AG-0011-R10A-SM-2HMLA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971485
abnormality of the abdominal organs	GWASdb SNP-Phenotype Associations	1.0	0.076822
SNAI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35967
pancreatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.384451
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5172
COX4I1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99012
CRCGN008_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.05068
adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064241
Pyloric mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.177
PELO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31859
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062106
ERCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44698
ZKSCAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29211
GTEX-TSE9-0011-R6A-SM-3DB7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1906
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
BHK cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.859
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829872
GSE202434,GSE202438_10_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DPP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.322
CHP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45852
TMEM54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7054
GSE214931_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH28	CCLE Cell Line Gene CNV Profiles	-1.0	-2.04346
MAN1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82251
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	6.20024
GTEX-T5JC-0426-SM-32PLO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38798
NCI-H1993	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MRPL36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0274
MARIZOMIB	DGIdb Drug Targets 2026	1.0	3.78086
Brain Lower Grade Glioma_LGG_TCGA-FG-7641-01B-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN009_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.17286
ARL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05259
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52086
LYSMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35743
GGN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61912
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36553
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01172
CALML4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10574
CTBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44154
Sessile cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.7
GTEX-RWSA-0126-SM-2XCBB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07562
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8984
transcriptional	GeneRIF Biological Term Annotations	1.0	null
HS-683 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.777
CRCGN012_HEPG2_24H:E07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.52662
RABL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00363
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42703
GTEX-T2IS-0011-R6A-SM-32QP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1462
Acute Myeloid Leukemia_LAML_TCGA-AB-2887-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-V1D1-2226-SM-3NMAX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17441
periodontitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.173314
PL18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RU72-0011-R6A-SM-2TF71	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57002
smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061437
TAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92955
CI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55053
urinary bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.151556
Endocarp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.999
CRCGN015_HEPG2_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.4379
SEBOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42249
Brain Lower Grade Glioma_LGG_TCGA-TM-A7C4-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6699
Carcinogenesis	DisGeNET Gene-Phenotype Associations	1.0	null
TRMT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.93359
UMPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86152
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.105
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.0546
GTEX-TSE9-0011-R4A-SM-3DB7H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926536
GRM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79193
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.80821
MT-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.564
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A913-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHTF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76378
CCNK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74991
HEC50B	DepMap CRISPR Gene Dependency	1.0	2.34265
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070019
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.076
GSE236502_1_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
SLC12A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77894
POU1F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74068
CNOT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25986
GABPA_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RNASE11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20661
A4/FUK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.851901
MACO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37707
Spinal cord injury	WikiPathways Pathways 2024	1.0	null
HS746T	CCLE Cell Line Gene CNV Profiles	1.0	1.49394
GTEX-WRHU-2826-SM-3MJG8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877016
plant form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05937
496100652_PCx_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.32172
HMGCS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81585
Lymphoma	DisGeNET Gene-Disease Associations	1.0	null
Chloroplast thylakoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.989
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5563
GSE111247_14_v_3_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
superior occipital gyrus, left, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18508
Gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	3.602
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15001
IARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73886
GTEX-TSE9-0011-R10A-SM-3DB7O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03686
SURF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24453
GTEX-QMR6-0011-R5A-SM-32PKT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868127
MOB3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22942
GTEX-X585-0011-R10A-SM-46MUY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32038
SGS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.002
fh1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.603
CRCGN011_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.43813
KP-N-YS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Spastic hemiplegia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.087
ACHE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76667
MYT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89743
GTEX-QDVJ-1726-SM-2I5FX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00407
Pancreatic adenocarcinoma_PAAD_TCGA-PZ-A5RE-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVJO-0011-R10A-SM-2S1QJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20406
ARC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.76
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SWAP70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26159
GTEX-NL3H-0011-R5a-SM-2I3GB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10487
Periodontal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.123
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22657
VIPAS39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30656
HELB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56073
HEP_3B2_1-7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SKM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MDST8	DepMap CRISPR Gene Dependency	1.0	3.00195
NEC8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ACAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36519
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.45231
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6963
SNX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34185
CRCGN014_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.92199
18855877-TableS2	GeneSigDB Published Gene Signatures	1.0	null
496100323_FWM_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.3201
SPINDOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78715
20436685-ST4-2	GeneSigDB Published Gene Signatures	1.0	null
KLM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.933803
CNOT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88225
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.933784
SLC19A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4521
disease of cellular proliferation	GWASdb SNP-Disease Associations	1.0	0.049443
A427	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-P44H-0011-R5A-SM-2XCEX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10133
PMC10794847-mmc2.xlsx-PBRM1_KD_up-Table_S1_Differentially_expressed_genes_with_PBRM1_knockdown_in_the_progenitor_state_Related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ECD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5192
BORTEZOMIB	DGIdb Drug Targets 2026	1.0	0.0879269
WIL2-NS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-X4XX-0011-R6B-SM-46MWP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67023
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.16105
MRPS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76753
GTEX-S7SF-1626-SM-3K2AY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968772
SERINC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82646
Adrenocortical carcinoma_ACC_TCGA-OR-A5JT-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
head of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.951468
competes	GeneRIF Biological Term Annotations	1.0	null
Chloroplast thylakoid membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.847
SETD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18713
GULP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25546
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-124-3p	MiRTarBase microRNA Targets	1.0	null
ovary	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.079324
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16116
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.256228
GTEX-XMD1-0011-R6A-SM-4AT5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4051
ezh2	GeneRIF Biological Term Annotations	1.0	null
GTEX-OXRN-0011-R10A-SM-2I5GC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953509
EWS-ERG-20517297-CADO-ES1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZNF397	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52813
EBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46144
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.69762
DIS3L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21126
Exocuticle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.344
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-4_E2F8-Gene_E2F8	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN016_MCF10A.TP53.M_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.47633
H3K27me3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
clathrin-coated endocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.021
HCC-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC2935	DepMap CRISPR Gene Dependency	1.0	2.12782
GTEX-WHSE-0126-SM-3NMBT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1664
TYMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.68373
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EI-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ADAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95907
TRAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33944
PRAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11753
STX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52375
GOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25211
GSE184356_1_v_2_tfam_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29618
bone marrow	HPA Tissue Gene Expression Profiles	1.0	0.91142
RNF144A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60598
GTEX-WZTO-0011-R7B-SM-4E3IS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17518
CAMK2N2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90463
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29737
Neuroblastoma	DisGeNET Gene-Disease Associations	1.0	null
Osteosarcoma	DisGeNET Gene-Disease Associations	1.0	null
ZSCAN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80728
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25989
PARP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03587
GTSE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.454
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6594
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6286
LRP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92531
their	GeneRIF Biological Term Annotations	1.0	null
KNOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.6446
GTEX-NPJ7-0011-R1a-SM-3GACT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30826
VIIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02307
SPRED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54638
ORC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38681
Lung squamous cell carcinoma_LUSC_TCGA-77-8144-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAPRE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.38456
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.149
NTAQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54537
Lung squamous cell carcinoma_LUSC_TCGA-85-8049-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.393746
pancreatic neoplasms	GAD Gene-Disease Associations	1.0	null
Steroid Sulfatase Deficiency Disease	DisGeNET Gene-Disease Associations	1.0	null
RUNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56027
FADU	DepMap CRISPR Gene Dependency	1.0	2.58443
GTEX-XLM4-0011-R4B-SM-4AT5C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929115
mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.123524
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1809
HCC1359	CCLE Cell Line Gene CNV Profiles	1.0	2.25957
brain	HPA Tissue Gene Expression Profiles	1.0	0.842275
HCN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12832
organ system cancer	GWASdb SNP-Disease Associations	1.0	0.05331
TTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89672
pyloric mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.15495
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Chl	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.507
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.802
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29737
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3328-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Estrogen Receptor-Negative Breast Cancer	DisGeNET Gene-Disease Associations	1.0	null
STAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55882