association	dataset	threshold value	standardized value
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.32261
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.842035
flecainide-3761	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
chlortalidone-6800	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
CPNE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.786
IRF2BPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09493
CHD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68981
CLOCK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2071
VANGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48183
COLO-684	GDSC Cell Line Gene Expression Profiles	1.0	3.25132
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:G19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05725
U266B1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.66344
posterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.94672
6-azathymine-2827	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K97839095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04111
BLCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8817
FAM131B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38967
HBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34311
APOBEC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22205
BRD-K49584388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04777
KASUMI6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44185
TSEN54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29179
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48945
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22896
ornidazole-5064	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K14251637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84284
CRCGN016_MCF10A.TP53.M_24H:C08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17336
CRCGN014_HEPG2_3H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.8659
MFSD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34197
altizide-6829	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC9305137-PATH-256-297-s005.xlsx-CIC_associated_DE_genes_IDH1-R-Unnamed_1_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
MEX3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29703
CHP126	CCLE Cell Line Gene Expression Profiles	-1.0	-1.96207
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-AAQO-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EXTL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01755
U-87-MG	GDSC Cell Line Gene Expression Profiles	-1.0	-2.1113
PAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23902
ASB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80041
LRRC26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03151
BRD-K88150784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23485
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.917302
EPLC-272H	GDSC Cell Line Gene Expression Profiles	-1.0	-1.71709
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.890616
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058921
HCC95	CCLE Cell Line Gene Expression Profiles	1.0	1.40751
ACSL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89805
propoxycaine-6803	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCIH650	CCLE Cell Line Gene CNV Profiles	1.0	2.4993
BL5906 (NFRKB)	NURSA Protein Complexes	1.0	null
BRD-K24109044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40638
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.96535
BRD-K73573019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28299
fenofibrate-7432	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K26200435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41662
BRD-K23749313	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30264
T84	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
CZIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46551
RTN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35405
N-acetylmuramic acid-4406	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K26117128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10486
ZNF836	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66064
PHF20L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40485
BRD-K06537903	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20727
cellular_component	GO Cellular Component Annotations 2015	1.0	null
BRD-K19418944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08876
MAFF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00595096
MGE-Lateral region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.48467
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.835626
BRD-K60547079	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47783
Pharyngeal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.107
BRD-K82922770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06443
terconazole-4407	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NDUFAF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7873
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48945
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.980055
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.920716
BRD-K69613314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.42375
ergocalciferol-2442	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K21009787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72249
POM121	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20954
CRCGN014_HEPG2_24H:F02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08773
CA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32543
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02414
BRD-K15160749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.77925
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.888819
BRD-K30581008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22689
HSPBAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23845
BICR31	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41733
BRD-K19411393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03429
BRD-K67104687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10064
TSC22D4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27262
BRD-K23085156	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0023
salivary gland	GTEx Tissue Gene Expression Profiles	-1.0	-1.38034
BRD-K78755361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00192
DNASE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93324
BRD-K49573242	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00899
NUDT17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6917
PCNX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74889
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
HLA-DOA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84828
TBX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1418
RNF38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90731
496100459_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.55228
IGFBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60842
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03238
BRD-K88494268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09191
HOP92	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.03126
nr2c2_20864514_liver_1yo_lof_mouse_gpl4134_gse21903	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.520204
TLE5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99414
ARHGAP21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57361
Rectum adenocarcinoma_READ_TCGA-AH-6547-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K74963702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47677
KLF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93218
STK35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31411
CREB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25618
PPID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18477
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MFSD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06264
BRD-K54224946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04581
ELAVL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97737
BRD-K81932943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20592
DEK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73116
subcuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01098
BRD-K89933563	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14642
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K07988588	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.29795
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05808
ventrolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14817
U251	GDSC Cell Line Gene Expression Profiles	-1.0	-1.58116
BRD-K47599661	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1421
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8881
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA1 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18472
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20V-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN009_HEPG2_24H:D22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17545
CCDC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37958
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16136
HCC1833	CCLE Cell Line Gene Expression Profiles	1.0	1.55284
COLO783	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.22128
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.233
LOUCY	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39891
substantia nigra, reticular part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13441
Lamina epithelialis mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.7
LMBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23871
CEBPA-26348894-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K49051633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.32896
CRCGN016_MCF10A.TP53.M_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.39356
CRCGN008_HEPG2_24H:M12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.49705
Thalamus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.31354
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE240468_3_v_2_nfyc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CAPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68257
RBM46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64875
BRD-K62370517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62063
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-4098-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K47574423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11181
WFDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54207
XRCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98288
BRD-K43364707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0472
H3K27me3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEWO	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6412
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.930301
BRD-K83832060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06759
Female germ cell nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.075
roxithromycin-4192	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KLF4_01_341	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.67172
BRD-K67856917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25549
BRD-K35171408	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37956
methacholine chloride-5773	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5974
PATL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67096
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
pimasertib	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67577
harman-4408	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MANBAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17159
UACC257	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.880379
BRD-K28258038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44722
ME-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056011
CRCGN015_MCF10A.WT.HP_24H:C02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01343
TTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89672
BRD-K71502099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21411
ZNF780A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01381
Mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	3.151
orbital frontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02093
monorden-6178	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BCL6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92327
ESR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65575
PMC2263127-pone.0001816.s001.xls-E2F3_up_Bild-Symbol_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K92725027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55978
DNAJC19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02242
BRD-K21996189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05106
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
BRD-K67716105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15974
NONO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79081
RRAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40371
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.1478
SELENOT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72902
MOAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39451
BRD-K78192025	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05836
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.843615
MDA-MB-231	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-NA-A5I1-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SAMD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19323
TE441T	CCLE Cell Line Gene CNV Profiles	1.0	1.98348
KLM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.909935
Proteasome storage granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.18
ASB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63199
CLDND1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00584558
BRD-K47690679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4972
molecular layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.849869
SU-DHL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.891551
superior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.873793
BRD-K95543908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20261
Vestibulocochlear nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.534
ART5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40507
BRD-K64698855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81743
DMWD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50404
ARHGAP23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97628
SU-DHL-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13218
NCIH1703	CCLE Cell Line Gene CNV Profiles	1.0	1.63341
Dental plaque	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.707
NDUFB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26284
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04141
BRD-K58985886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19566
TXNDC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9638
CRCGN014_HEPG2_24H:A03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.91878
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43881
Cowpox	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.112
Hindbrain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MAT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51801
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0318
HES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7924
RDH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4565
DAPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13008
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.40395
PRSS53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94571
CRYBG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00492
Noc complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.912
BRD-K47988839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.09041
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0256
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4843-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71186
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.988929
BRD-K30792491	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78004
UFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32422
oxaprozin-4352	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.59738
cerebellum	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CRCGN014_HEPG2_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3272
WDR45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49866
medial mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.3945
VMRCLCD	CCLE Cell Line Gene Expression Profiles	1.0	2.15959
BCL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98631
DKMG	CCLE Cell Line Gene Expression Profiles	1.0	1.35882
GSE235587_2_v_1_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	1.0	null
ITPR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50531
HCC1599	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49022
BRD-K35646839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16829
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058885
SUPT11	CCLE Cell Line Gene Expression Profiles	-1.0	-2.24528
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8061-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH23	CCLE Cell Line Gene CNV Profiles	1.0	1.54725
USP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64226
calcium pantothenate-4189	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
APOL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40181
DCLRE1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80273
BRD-K86159732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41162
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3328-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
saliva	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K34405227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85647
Brain Lower Grade Glioma_LGG_TCGA-DB-5270-01A-02R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
extracellular region	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K95323025	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02928
STAT5_01_279	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.32734
GPAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59735
RGS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03144
EFNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38046
Lung squamous cell carcinoma_LUSC_TCGA-39-5024-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AMMECR1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8697
T47D	CCLE Cell Line Gene CNV Profiles	-1.0	-2.8634
STEAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10875
UBFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79006
CAS1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.78868
BRD-K21386594	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07738
outer SZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.828517
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_42_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN016_MCF10A.WT.HP_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1309
SNU840	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.00501
HAE cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.644
BRD-K20030272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40682
SCC-3	GDSC Cell Line Gene Expression Profiles	1.0	1.49608
BRD-K02778241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61451
Lung squamous cell carcinoma_LUSC_TCGA-22-5491-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100414_TCx_probable Alzheimer's disease_no TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.72932
SJSA1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.38077
NCI-H835	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-WY-A85A-01A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K87666020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26673
SYT12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97421
NTF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69082
CD8+_Tcells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.01648
BRD-K96615474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19197
SLC25A52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9781
primary visual cortex (striate cortex, area V1/17)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.52553
BRD-K05857732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1578
BRD-K33016067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1425
OGFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80339
A253	CCLE Cell Line Gene Expression Profiles	1.0	1.46299
SLC25A15	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00559316
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22793
MAP3K3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22324
BRD-K05070188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66667
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.157
HS746T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62338
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.05271
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.853705
CRCGN016_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.01113
DYNLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30951
MYO10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17486
BRD-K03361106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17755
pallidohypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.943673
Liver hepatocellular carcinoma_LIHC_TCGA-KR-A7K7-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mouth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.297089
BRD-K98431828	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16356
SUIT-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LC-1-SQ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.573616
HUNS1	CCLE Cell Line Gene Expression Profiles	1.0	2.07007
SARS-CoV MA15_Day1-PFU-10^3_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.82018
CTCF	ENCODE Transcription Factor Targets	1.0	null
BRD-K41307047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45768
BRD-K29802952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19412
BRD-K63803358	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27341
NR2F6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2122
KLF13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.0839
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.86154
BRD-K80439500	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04431
MEST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44312
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13392
BRD-K33967062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01787
GPR150	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60993
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.42668
ZGPAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37265
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051567
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.54289
GSE240030,GSE252532_0_v_2_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PPP1R9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0142
TP53-18474530-U2OS-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
benzethonium chloride-7207	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZNF554	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89233
BRD-K71210410	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58708
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2634
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MEC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51225
BRD-K22508525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1348
HOXA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21519
c-MYC_KD_GDS2526_112_human_MCF-7 BREAST CANCER cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CCNL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46479
BRD-K52391588	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03518
TIFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24654
SLC25A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03983
BRD-K09191014	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32235
BRD-K50710722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95926
LN18	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49014
paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.976342
BRD-K30625175	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41477
SK-MEL-28	GDSC Cell Line Gene Expression Profiles	-1.0	-1.71169
INPP5F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93482
SUN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00193
BRD-K36393312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07519
INSIG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9587
propantheline bromide-4214	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SLC25A22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72227
Lung squamous cell carcinoma_LUSC_TCGA-77-7141-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193351_1_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
hydralazine-2311	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K73442516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03785
SK-OV-3	GDSC Cell Line Gene Expression Profiles	-1.0	-1.76016
NINJ1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00474232
BRD-K50068274	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39608
BRD-K83934572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4271
C19orf73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67323
BRD-K36002293	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17447
BRD-K54079231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05474
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.917954
COLO-679	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SKMEL1	CCLE Cell Line Gene CNV Profiles	1.0	2.02228
THOC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00538
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48945
HCoV-EMC2012_3Hour_23631916_GSE45042	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.22599
BRD-K26196953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21585
Cancer of the testis_Testis_GSE1818	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.48217
phenformin-2312	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.442
AMIGO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45537
HES4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66291
ARHGEF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19592
CRCGN017_MCF10A.TP53.M_24H:A03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3229
BRD-K60337438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00079
BRD-K01148617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21168
bsc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.695
TNFAIP8L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77234
Calu-6	GDSC Cell Line Gene Expression Profiles	1.0	1.42376
SNU349	CCLE Cell Line Gene Expression Profiles	1.0	1.91023
CBP-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.66778
VCPKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84921
BRD-K82683018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07051
TXLNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67228
BRD-K73001304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.29412
BRD-K77109731	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10621
TIMM10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03412
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17601
HOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1895
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
exocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
17616640-TableS3	GeneSigDB Published Gene Signatures	1.0	null
BRD-K12683022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16621
VZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02953
BRD-K89744662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18267
FUT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71531
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6913
MZ in retrosplenial cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.92358
CRCGN008_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5878
FAM72A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86597
FOSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.72191
RPE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32931
TUHR10TKB	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57086
Acute Myeloid Leukemia_LAML_TCGA-AB-2872-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
extracellular region	GO Cellular Component Annotations 2015	1.0	null
stratum radiatum of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30391
LC-2-AD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MTDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8829
IZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.941585
BRD-K42785890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.26238
MHH-PREB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MLLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94874
Hypopharynx cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.433
496100507_FWM_dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.8866
BRD-K61494613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11309
trichostatin A-6171	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LHX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45208
BRD-K15343038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9617
Hypopharyngeal squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.795
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.07322
CDC25B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66565
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.47519
C11orf98	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.43586
ISL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3227
BRD-K51335814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76287
Trachea	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8605
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.998911
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1021
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
DNAJC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90933
XPNPEP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79944
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A5SO-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MITF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11217
BRD-A90289676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08229
SHH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52199
S1PR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83103
Breast Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.48972
ZNF254_01_127	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.44823
POLE3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00459432
SMURF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79293
RALY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41812
sulfachlorpyridazine-3769	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K21582416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10316
IFITM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6632
ACAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06862
BRD-K56022813	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14353
lateral ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.40236
CD56+_NKCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.10199
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09179
BRD-K21990363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04248
CLIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00898
SOX2-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K42757676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19695
U-CH2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KR-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K13792178	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35149
CASC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92679
Breast mucinous carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.012
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44694
BRD-K77697841	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32181
BEX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21174
BRD-K63462027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43527
BRD-K53121826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19991
KCI-MOH1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10409
NCIH1648	CCLE Cell Line Gene Expression Profiles	1.0	1.37081
FCHSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23948
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.871903
BRD-K03262163	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58476
BRD-K35383890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34076
BRD-K27049948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22343
BRD-K47109712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39637
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3R5-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7455
BRD-K14970242	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1737
SN12C	GDSC Cell Line Gene Expression Profiles	-1.0	-1.44659
BRD-K22974051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.24236
BRD-K44224150	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37683
4T1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.699
z85	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.718
RPS20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51368
TM7SF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76846
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K35617935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27388
sulfanilamide-3449	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SSX2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97577
hsa-miR-1272	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
BRD-K28294686	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6815
DJM-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.82266
NUDHL1	CCLE Cell Line Gene CNV Profiles	1.0	1.4231
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.97254
CHPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70207
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.39076
OXA1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32198
NDUFV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52893
pramocaine-3894	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
THP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.94464
CHSA8926	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H650	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KYSE30	CCLE Cell Line Gene Expression Profiles	1.0	2.4196
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.930401
C1orf116	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82576
metencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PIDD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27994
BRD-K70042405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35171
NCI-H650	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
AHSP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22147
BRD-K31203610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05172
H3K79me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Subrhabdomeral cisterna	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.826
GAPDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39396
hsa-miR-4766-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
EIF5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93552
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.48342
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.78512
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.78293
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.980055
BRD-K35964249	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22403
CCDC51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61174
NDUFS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18255
cervix uteri	GTEx Tissue Gene Expression Profiles	1.0	0.837227
BRD-K78395012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36276
TRIM61	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52862
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8097
ADCY5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21864
RPS6KB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21915
T-REx 293 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.519
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EJ-11A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IkappaB kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.265
SEMA5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32533
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:E21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01615
PMC8065135-41467_2021_22068_MOESM6_ESM.xlsx-E_MYOG_binding_in_downreg-Unnamed_1_MYOG	Rummagene Transcription Factor Associations 2026	1.0	null
CMK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K64840743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39736
MDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30624
C-4-I	COSMIC Cell Line Gene Mutation Profiles	1.0	null
subgranular zone of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.2328
496100563_PCx_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.19161
C1orf226	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44164
DLX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24545
CAL12T	CCLE Cell Line Gene Expression Profiles	1.0	1.6118
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A216-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer V of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.944353
Sublingual gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.981
RPUSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5014
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K03331449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96183
H3K9me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF674	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80907
PCDHB14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9368
Adrenocortical carcinoma_ACC_TCGA-OR-A5K2-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-XN-A8T3-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.6853
BRD-K74150320	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29052
CRCGN017_MCF10A.WT.HP_24H:P15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.404
fluphenazine-5234	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AXIN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00388126
FaDu cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.796
DMKN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54404
midbrain reticular formation	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34221
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7234
liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.341272
UQCRQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78244
NCIH2073	CCLE Cell Line Gene CNV Profiles	-1.0	-1.91194
TLCD3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93464
tail of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.0306
GSE102467_3_v_0_pazopanib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Salivary gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	3.151
MZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.927649
Dental caries	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.224
CIR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32206
SLC37A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37905
bepridil-4613	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
inner SZ in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.966232
BRD-K64165176	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20396
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02534
MDAMB436	CCLE Cell Line Gene CNV Profiles	1.0	1.48487
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-3.12968
AEN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49807
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CLK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1645
ARPC5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0056063
BRD-K01296372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0803
AMDHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10944
EBC1	CCLE Cell Line Gene CNV Profiles	1.0	1.47331
CCDC160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30343
Cerebellum	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.941203
DU-145	GDSC Cell Line Gene Expression Profiles	-1.0	-2.75973
RIC8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28674
CAB39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50282
BRD-K81728234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04843
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13658
LIN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64045
HT29	BioGPS Cell Line Gene Expression Profiles	1.0	1.45454
RT4	CCLE Cell Line Gene Expression Profiles	1.0	1.411
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.805
ZBTB34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29259
KMS-28BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21202
BNIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78836
chr12_11308868_G_A_b38	GTEx eQTL 2025	1.0	1.13631
Myeloid leukemia associated with Down Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
CRCGN015_HEPG2_48H:O13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.16988
DNAJC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4598
TAB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5902
Pancreatic adenocarcinoma_PAAD_TCGA-H8-A6C1-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YV-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LMSU	CCLE Cell Line Gene CNV Profiles	-1.0	-2.27081
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.20837
ventral tegmental area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16674
COLO704	Achilles Cell Line Gene Essentiality Profiles	1.0	1.36185
VMRCRCW	CCLE Cell Line Gene Expression Profiles	1.0	1.38093
A4/FUK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.835626
DDT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04809
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.887667
DMS53	CCLE Cell Line Gene CNV Profiles	1.0	1.52595
ZNF217_OE_GDS4885_317_human_MDA-MB-231 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K58168959	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24464
SNAI1_OE_GDS4596_344_human_SW480 - Colorectal cancer cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3359-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HUH1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44006
IV, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.45227
TPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93362
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16136
Liver hepatocellular carcinoma_LIHC_TCGA-NI-A4U2-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HES6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1265
CSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01652
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.91568
DLD1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.07384
lateral hypothalamic area, tuberal region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.881164
BRD-K23024526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63876
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8522
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9251
orbital frontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.996059
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47238
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.232
NID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80597
florfenicol-3083	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K77869064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18049
gracile nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19776
Sublingual gland duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.148
MEWO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41163
primaquine-4263	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MYT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89743
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41808
RCOR1	ENCODE Transcription Factor Targets	1.0	null
NNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27544
HNF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99249
ARFRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13016
Proline-rich protein	InterPro Predicted Protein Domain Annotations	1.0	null
ETK-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE116492,GSE116495_3_v_2_stag2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4770-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DICER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14569
BRD-K23064726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15211
JM1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hindbrain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3HZ-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GFY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59813
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16813
BRD-K47783463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70697
SEC11C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15685
cefazolin-7385	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
fluphenazine-6954	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
calcium folinate-3703	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN015_HEPG2_48H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.72031
CDK2AP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.69369
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GU-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C6orf47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67016
BRD-K78866630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14968
CAL-12T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K44692299	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39489
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.63571
CRCGN016_MCF10A.TP53.M_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.38108
cerebellum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.93289
CRCGN014_HEPG2_24H:I24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.86707
APOBEC3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3924
BRD-K68858233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5142
BRD-K29756429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03005
CRCGN016_MCF10A.TP53.M_24H:A22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2506
BRD-K37865727	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36997
Brain Lower Grade Glioma_LGG_TCGA-FG-A60L-01A-12R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.891551
HCC1954	CCLE Cell Line Gene CNV Profiles	-1.0	-1.92672
Brain Lower Grade Glioma_LGG_TCGA-QH-A86X-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K09689420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15397
BRD-K83946740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18247
Carcinogenesis	DisGeNET Gene-Phenotype Associations	1.0	null
layer IIIu of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.45767
CRCGN016_MCF10A.TP53.M_24H:M12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12904
Acute Myeloid Leukemia_LAML_TCGA-AB-2967-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K58586013	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58153
BRD-K08527280	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4782
TDRD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16568
HGH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41911
Prostate adenocarcinoma_PRAD_TCGA-G9-7519-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Parotid gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.662
CRCGN015_HEPG2_48H:L02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.77708
KALS1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.43462
NDOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70715
MFH-INO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
amantadine-4222	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NEMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.52002
Acute Myeloid Leukemia_LAML_TCGA-AB-2993-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ENOSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64729
Adenoma_Adrenal gland_GSE8514	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.58792
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K44265418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39737
BRD-K61661017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2359
periaqueductal gray substance, ventral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.64639
LEPROT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51776
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27863
K562	BioGPS Cell Line Gene Expression Profiles	1.0	1.13352
BRD-K04468899	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32767
UOK101	Achilles Cell Line Gene Essentiality Profiles	-1.0	-3.5559
CLTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61321
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4VZ-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K27011412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35478
NMRK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62739
Thyroid cartilage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.537
ZNF519	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75528
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A6NN-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in midcingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.64384
BRD-K54351101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30076
SDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29038
MRPS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87442
ethionamide-2495	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K99214816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04299
medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.83348
BRD-K14122415	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06012
sulfadimidine-3765	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
nucleus of the diagonal band, left, horizontal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.849366
Skin Cutaneous Melanoma_SKCM_TCGA-GF-A6C9-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.74487
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29H-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN013_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26655
dihydroergotamine-4502	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K90675978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09773
Mesothelioma_MESO_TCGA-MQ-A6BL-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.62938
SLU7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10788
NXF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39718
STAU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86138
Acute myeloid leukemia with minimal differentiation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.333
alcuronium chloride-7345	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Germinal vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.075
CALHM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44369
TLR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18674
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
cancer stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.759086
BRD-K38450726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18227
H3K9me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K26091803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14177
PMEPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66341
MZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.40692
WASHC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53296
SARS-CoV MA15_Day7-PFU-10^2_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.05003
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13658
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A6MF-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Exocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	3.151
Epibranchial	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.106
RPL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90445
ZBTB32	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5734
CAL120	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45604
HAGH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81742
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.904333
Brain Lower Grade Glioma_LGG_TCGA-CS-6186-01A-12R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCEANC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31603
SLC15A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22544
BRD-K95369587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07357
orbital frontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12705
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.996266
lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.45879
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.25774
BRD-K97339945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18149
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.915851
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.860944
HC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
18855877-TableS2	GeneSigDB Published Gene Signatures	1.0	null
BL2293 (EDC4)	NURSA Protein Complexes	1.0	null
Smallpox	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.94
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1546
tail of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.49557
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34043
superior colliculus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.54754
BRD-K85622666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01985
DUSP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79176
BRD-K50830147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63126
paracentral lobule, posterior part, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.833503
KG1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74318
BRD-K44576681	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32842
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.17224
RUNX1-27514584-CHIP-SEQ-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3OO-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sotos syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.056
APLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.846
BRD-K40318276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45806
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2036
ETV5::HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9623
REXO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63354
DHX34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93459
cefixime-4390	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K41655405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37779
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.7916
BRD-K57938735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29597
Brain Lower Grade Glioma_LGG_TCGA-HT-7472-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.16897
AGAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53959
BRD-K79855662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07982
ESRRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38277
callus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.02075
BRD-K66187822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16418
lynestrenol-6756	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K49005954	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55041
CRCGN016_MCF10A.TP53.M_24H:C18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.32721
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.31852
496100295_TCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.05171
PA-TU-8988S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.961951
HTATIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96302
peroxisome	LOCATE Predicted Protein Localization Annotations	1.0	null
MHHCALL4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40431
EDN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00372229
medial parabrachial nucleus,right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.839231
VZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08474
VPS37D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95311
bephenium hydroxynaphthoate-4668	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8503
Brain Lower Grade Glioma_LGG_TCGA-DU-A6S6-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF100_01_124	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.18644
ZNF876P	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93129
Acute Myeloid Leukemia_LAML_TCGA-AB-2983-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OE33	Achilles Cell Line Gene Essentiality Profiles	1.0	1.28649
BRD-K65166009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06094
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8522
APOE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82522
PYCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65923
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5706-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CERS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49463
STAT3	ENCODE Transcription Factor Targets	1.0	null
BRD-K83667863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06024
carbimazole-2437	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Hypogonadotropic hypogonadism 6 with or without anosmia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.316
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K36289678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54089
SH10TC	CCLE Cell Line Gene CNV Profiles	1.0	1.91299
TBKBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.03405
IKBKG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70684
BRD-K72029544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24118
OV7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28119
CALM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28035
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47238
RNF24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60827
Salivarygland	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55362
TRAF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32787
ARHGEF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48697
ERCC6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24832
UNC13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23932
MARCHF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38745
THRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71734
facial motor nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.892882
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUR-01A-21R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JP-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K69241192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.21708
JHH-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
YES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1592
BRD-K74834319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17378
VZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05909
BRD-K98805845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24703
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A82E-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K32520360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19376
BL5529 (CCDC99)	NURSA Protein Complexes	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34509
BRD-K72452130	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75132
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07322
PDXP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2125
tranexamic acid-2248	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K08607520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29323
CYP2D6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38298
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3335-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K28314528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01532
BRD-K62193937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52381
HMOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95412
BRD-K24502602	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49814
oxantel-6738	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K9me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Hypopharyngeal carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.791
motor nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.947682
Colonic adenoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.72
RPL22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92319
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.853705
ZSCAN31	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4302
CCNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.76399
TAF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37804
BRD-K65789952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01363
rostral migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0182
BRD-K31783598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14734
BRD-K09258973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43266
PLEKHH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15489
hippocampus (hippocampal formation)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04431
TMEM92	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7817
BRD-K37253893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11408
Extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
BRD-K50976856	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94846
AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
Parotid gland duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.173
BRD-K41306114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49178
BRD-K37942718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37772
amygdaloid complex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.999641
SMAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07061
GDM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75875
MSRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60459
TMEM129	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82161
496100646_TCx_probable Alzheimer's disease_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.77448
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.904925
BRD-K35407043	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1412
BRD-K10325583	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10071
plant form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.302118
BRD-K75989234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33533
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TU-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KRBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80612
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17295
MUTZ5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49545
BRD-K52956006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13971
salivary gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
SDHD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00571104
SHKBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28904
201T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC3879300-pone.0084292.s002.xlsx-SPD_dataset-Gene_symbol_HOXD13	Rummagene Transcription Factor Associations 2026	1.0	null
ENOPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72579
BRD-K55393423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.63511
BRD-K90649428	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52024
hippocampus (hippocampal formation)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12705
BRD-K42032479	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15234
BRD-K35953312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06267
Human - Lung v1 - L2 - Serous	HuBMAP Azimuth Cell Type Annotations	1.0	null
EXOSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86096
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.13807
JHOS-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K09261031	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1604
Lymphatic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.079
BRD-K02024244	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70025
CRCGN008_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6464
BRD-K42247636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58446
CHRNA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08401
CRCGN015_MCF10A_48H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.00701
TSEN15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22483
CTPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37441
D-247MG	GDSC Cell Line Gene Expression Profiles	-1.0	-2.05433
BLTP3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89614
BRD-K50510710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90462
Lymphatic system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
Lung squamous cell carcinoma_LUSC_TCGA-33-4538-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YLPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75253
17616640-TableS1	GeneSigDB Published Gene Signatures	1.0	null
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.980055
CDK13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03041
SARS-CoV MA15_Day7-PFU-10^5_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.42044
IL27RA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54101
BRD-K65737790	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46588
ECH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24605
SLAIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58844
A172	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.03456
SS18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.26742
pontine raphe nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02394
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8218
VZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.929843
PMC4060771-170289.f1.pdf-537-TEAD3_TEAD3	Rummagene Transcription Factor Associations 2026	1.0	null
ACAD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3749
LS513	CCLE Cell Line Gene Expression Profiles	1.0	1.49634
ARV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17518
HMX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16468
TENM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21929
basolateral nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.832495
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041302
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.980055
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.31284
VZ in caudal cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25732
TGFBI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66591
orbital frontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.964978
VMRC-LCD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K97086564	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44599
SARS-CoV MA15_Day7-PFU-10^3_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.56448
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GJC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3878
SuperiorCervicalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.865536
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1041
GTF2IRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32551
MDAMB157	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47679
HOXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57247
PMC9643473-Table1.xls-MAF_0_005-HGVS_gene_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34083
BRD-K09511124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.38281
RL95-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K49298555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19398
terguride-5400	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CP-320650-01-3908	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
external segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06578
Brain - Hippocampus	GTEx Tissue Gene Expression Profiles 2023	1.0	2.19567
PMC12486367-Supplementary_Data2.pdf-60-HES4_HES4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K19492738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22025
MOLM13	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.17316
ZNF431_01_128	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.43248
BRD-K07740919	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38113
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.853705
YMB1	CCLE Cell Line Gene CNV Profiles	1.0	1.74521
BRD-K21620541	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24767
spleen	GTEx Tissue Gene Expression Profiles	1.0	0.996807
PLEKHA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55012
BRD-K89514545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21114
FAM89B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7983
YWHAE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79824
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8841
EFNA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83218
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4971-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NALM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.9287
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.101
CAKI1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.3775
GIPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.29381
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041045
BRD-K62324460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01693
BRD-K16802067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09994
BRD-K15775306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31616
DNAJC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41909
SYNCRIP_OE_GDS4596_85_human_SW480	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K75041866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00232
CHAGOK1	CCLE Cell Line Gene Expression Profiles	1.0	1.72891
CLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05811
FURIN	Pathway Commons Protein-Protein Interactions	1.0	null
LSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.635
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4872
BACE1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00491782
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07117
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7774
MGAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36072
NLGN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1096
TRO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4896
H4K20me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K77399094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.10433
VAV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08002
OLFML3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4954
H3K27me3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-SNU-1	GDSC Cell Line Gene Expression Profiles	1.0	1.75597
SK-OV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41163
MFSD13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10154
SOBP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00496096
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4920-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
KMS-28PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24069
ITM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34878
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.90235
MSANTD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83297
stratum lacunosum-moleculare of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.886431
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-12q13_11_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
MAP7D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0673
SP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.897078
LRP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55914
CYTH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25375
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.11321
Saliva	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K26051127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02616
Tooth enamel	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.798
CYP27B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50567
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K42671261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02241
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6618
TMEM51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02219
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.57732
extracellular region	LOCATE Curated Protein Localization Annotations	1.0	null
BRD-K70949282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.27738
CRCGN015_HEPG2_48H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.31246
ZSCAN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60759
TUBB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77131
COA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98465
NARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60528
BRD-K30220159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94204
supramammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.32822
NCI-H1869	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38548
BRD-K53499221	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19532
magnocellular (medial) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.41608
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41163
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.91166
exocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.447192
PSAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70945
salivary gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.592043
PMC2263127-pone.0001816.s002.xls-Terms_with_Genes_E2F3_up_Bild-Title_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K07697589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.202
BRD-K48987279	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29009
Pellicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.511
Prestwick-1080-4532	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
brain stem	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K00231307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52636
PGC1alpha_DEPLETION_GDS4989_283_human_A375P melanoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K73092207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47115
CD4+_Tcells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.879439
chlorcyclizine-4367	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K79946769	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66082
BRD-K95129711	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30739
abducens nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.26018
BRD-A05883068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02676
CD93	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00506953
BRD-K50600207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02653
HS6ST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94448
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.882205
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NFIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57125
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4845-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SF539	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.47435
Acute Myeloid Leukemia_LAML_TCGA-AB-2887-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.81763
BRD-K66179451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14435
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55133
DNAJC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20519
AURKAIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83564
LEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28443
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.72877
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5201-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FASTKD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76406
HIRIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19264
BRD-K02299361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46481
BRD-K13804959	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18522
BRD-A64761364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84477
BRD-K15833017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38873
496100448_TCx_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.68659
TP53	ChEA Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-7697-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H64	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9057
preoptic region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10513
Rotavirus infection of children_Peripheral blood mononuclear cell_GSE2729	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.4954
BRD-K66270896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.11028
Rectum adenocarcinoma_READ_TCGA-F5-6812-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUDT14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33686
HIF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74489
BRD-K74916896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10376
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29985
MZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.84701
BICR 31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32076
biological_process	GO Biological Process Annotations 2015	1.0	null
BRD-K15654812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05966
PROSER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78656
SLIRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44164
BRD-K03923461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28032
BRD-K60760423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1406
PCDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77052
hexamethonium bromide-1482	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
phthalylsulfathiazole-4653	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
METTL26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82773
UBE2G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04511
GMCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81351
786O	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.02156
BRD-K78403457	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07832
CRCGN012_HEPG2_24H:E07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.52099
PDILT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00579848
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K04409515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.028
Brain Lower Grade Glioma_LGG_TCGA-HT-A618-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Testis	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.03871
FURIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65833
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5099-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TTI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3255
BRD-K77119472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16968
hexestrol-6252	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC3712200-584604.f1.pdf-28-GRHL1_GRHL1	Rummagene Transcription Factor Associations 2026	1.0	null
RAPGEFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52986
raubasine-5459	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2897-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K85051145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3028
ANKRD63	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87733
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2439
PTX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62561
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4822-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10306
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3252
posteroventral (inferior) parietal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2398
BRD-K01121723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1255
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.927538
496100550_TCx_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.8875
HEC59	CCLE Cell Line Gene Expression Profiles	1.0	1.46034
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02414
CRCGN015_MCF10A.TP53.M_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14335
RND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02787
inferior occipital gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.992994
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.35128
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.949351
BRD-K40809590	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26851
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
arcuate nucleus of medulla, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.949164
TP73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22411
PARP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68379
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03238
496100341_TCx_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.20685
POU2AF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11033
BRD-K45013233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27277
BRD-K30895360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02357
RK-13 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.417
CRCGN015_HEPG2_48H:E22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.488
roxithromycin-2992	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GMEB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12045
RNF182	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43698
CCDC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14621
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.82559
NCI-H1341	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10353
NUGC2	CCLE Cell Line Gene CNV Profiles	1.0	1.91915
BRD-K88806312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34676
SPATA20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96548
Cerebellum	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.834939
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Hypopharyngeal Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
PARD6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76956
Vaccinia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.305
DOTC2-4510	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PIN1_DEPLETION_GDS4070_450_human_MDA-MB-231 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K91577886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.12173
NFX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91138
RABEPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06907
NAPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75783
PKN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66674
CXXC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06617
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A3MI-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DUSP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08819
CCDC77	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3101
BRD-K91624805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04913
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.03317
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7985
EXTL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34479
CAPN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53962
pargyline-2265	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ADD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.61691
BRD-K02715134	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02323
BRD-K39761541	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33841
SHSYSY-RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.86628
SNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11132
RAP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95518
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.64484
BRD-K86373784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59373
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A1-11A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.38
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.967414
Mesothelioma_MESO_TCGA-NQ-A57I-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
N-acetylmuramic acid-4582	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K88395026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03185
BRD-K12524155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.47354
PBX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30541
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4166-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K84334677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00807
BRD-K13807637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1857
HSC2	CCLE Cell Line Gene Expression Profiles	1.0	1.41595
tinidazole-3813	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K23598860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35237
ZIC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73269
NCOA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37819
BRD-K32176914	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83588
TP53-18474530-U2OS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Metencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K96057608	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.24374
hsa-miR-4452	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.5795
BRD-K21143905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3418
BRD-K28351377	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57257
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.927538
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22793
BRD-K38248920	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07344
UBE2Q2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40836
BRD-K30821056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10519
H3K9me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74546
MAVS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43109
BRD-K17405621	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30912
ZNF540	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12236
U343	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.2346
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0782
ZNF91_01_123	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.98634
NCIH146	CCLE Cell Line Gene CNV Profiles	1.0	1.61357
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5178-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUTM2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00674164
BRD-K82216975	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13827
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B7-01A-31R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FERMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00358
UNC13D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96322
Lung squamous cell carcinoma_LUSC_TCGA-85-8049-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8512-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CPC-N	GDSC Cell Line Gene Expression Profiles	1.0	1.97451
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24069
BIRC3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00444811
BRD-K11846531	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13602
BRD-K77074748	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24863
SLC27A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02024
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.69406
CBLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44515
CA3 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18235
KLF7_01_342	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.22278
RSRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20986
TRPM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00620671
SW948	COSMIC Cell Line Gene Mutation Profiles	1.0	null
gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.161716
CRCGN011_HEPG2_24H:M23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06085
Rectum adenocarcinoma_READ_TCGA-DC-6155-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MPPE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59246
tuberomammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.44035
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.092
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-4104-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34314
ZNF174	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53564
DTYMK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83299
H3K9me3_Rectal Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K10707948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54802
BRD-K49159670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29195
ZNF136	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38258
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
HOXB7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4227
PRADC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32698
FGF22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71699
Gingival fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.889
CTSG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00606035
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6247
CCZ1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68438
BRD-K47314501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07747
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6797-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IALM	CCLE Cell Line Gene CNV Profiles	1.0	2.90183
HDLM2	CCLE Cell Line Gene CNV Profiles	1.0	1.61494
extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BB30-HNC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UM-UC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.922063
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.987442
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.53407
CSB-26484114-CHIP-SEQ-FIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0027
ZNF284	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96833
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.63571
ME1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.58191
KMT5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38019
LN340	CCLE Cell Line Gene Expression Profiles	-1.0	-1.68062
fulvestrant-6197	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FBXO11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30108
BRD-K07278815	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.96641
BRD-K11631946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54856
parotid gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.89817
GDF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86365
AR_01_278	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.95195
WM115	CCLE Cell Line Gene Expression Profiles	-1.0	-2.8825
Hs-578-T	GDSC Cell Line Gene Expression Profiles	-1.0	-1.46211
TMEM126A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91048
BRD-K81931105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04803
mRNA cap binding complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.735
CTNNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84713
NRARP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5292
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.125
globus pallidus, internal segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.78751
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
NRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01107
CD1E	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0055898
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.835851
ZNF33A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19421
496100617_TCx_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.08322
GATAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97155
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Cellular anatomical entity	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
SPATA24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52464
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.6869
SOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26396
BASP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21712
heterozygous	GeneRIF Biological Term Annotations	1.0	null
BRD-K76318449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03699
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6519
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80K-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K95033255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82691
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1984
oculomotor nuclear complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.29171
BRD-K87821938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56855
BRD-K74445272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07299
BRD-K55402144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20959
TRIB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92384
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5108-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCC010	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SK-MM-2	GDSC Cell Line Gene Expression Profiles	1.0	1.64552
BRD-K94637240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4146
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.964474
EPHA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45856
FBXO34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85773
hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.364085
clopamide-3220	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
levobunolol-3015	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
piperine-3263	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.959347
MLXIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41687
Acute Myeloid Leukemia_LAML_TCGA-AB-2940-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7767
SLC39A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89271
CUX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13647
c-MYC_KD_GDS2526_109_human_Hela cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
TTYH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64705
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4352-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
P3H4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73438
GLRX2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00694513
KCNC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00530534
BRD-K96758498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74041
BRD-K06698399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04163
PNPLA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9134
CRCGN011_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.465
NCIH196	CCLE Cell Line Gene CNV Profiles	-1.0	-2.22599
MEF2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3512
BRD-K12223973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14786
TRIM37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13154
ZFYVE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99046
LN382	Achilles Cell Line Gene Essentiality Profiles	1.0	1.32594
KRAS.BREAST_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A97G-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7438
AU565	CCLE Cell Line Gene Expression Profiles	1.0	1.43598
BRD-K60123410	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25569
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27863
6-azathymine-2466	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K75844451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11802
CL-34	COSMIC Cell Line Gene Mutation Profiles	1.0	null
arcuate nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.32107
Sarcoma_SARC_TCGA-DX-AB2F-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17406
adult stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069555
KLF16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56818
PMC9643473-Table1.xls-MAF_0_005-Gene_refGeneWithVer_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5001-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K20454972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03673
exocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
WSU-NHL	GDSC Cell Line Gene Expression Profiles	1.0	1.95865
Rb-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.908
Submandibular gland duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.747
PTMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26185
ANAPC15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91092
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4700-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF189	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32581
B3GNT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00777
peripheral portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.15883
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3123
BRD-K72156149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22019
BRD-K13968264	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40557
BRD-K75036062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52051
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
UCHL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50787
NCI-H211	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K98891210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78996
PL4	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76455
KDM5A	ENCODE Transcription Factor Targets	1.0	null
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.352
RELB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61542
BRD-K29684372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47541
BRD-K67902591	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05832
POFUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62525
hsa-miR-4420	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
ZNF99	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70835
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.36992
COMMD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57829
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.65737
ZBTB17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34667
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.149
Brain Lower Grade Glioma_LGG_TCGA-HT-A5R9-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A7CF-02A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
epitiostanol-4204	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
body of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.882201
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.83133
SJSA1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.55861
BRD-K62288678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10807
ZNF438	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21356
ZNF264	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08064
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4351-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.63258
VAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7818
tonzonium bromide-4617	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
UM-UC-3	GDSC Cell Line Gene Expression Profiles	-1.0	-1.4889
MALSU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77489
Oculopharyngeal muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.091
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.53535
Prestwick-1100-3880	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BCKDK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82006
BRD-K30065842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00222
ethosuximide-7308	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21526
POU3F4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85117
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54J-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051978
BRD-K18856772	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76995
Cef cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.504
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XP-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMARCB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65296
CEP68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78549
NCKAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98288
ELK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8175
BRD-K80782159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05634
upper (rostral) rhombic lip_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.40236
SLC4A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03133
Sarcoma_SARC_TCGA-DX-AB2J-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HELA	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.17467
BRD-K30812092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60266
THEM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72522
RNF123	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.485
repaglinide-6135	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
benzthiazide-2989	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41018
BRD-K68401280	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26469
SEPTIN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37088
SP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08073
BRD-K39617634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64988
MYCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95495
BRD-K75981085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.31401
superior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04342
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.237
SLC35A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08087
BRD-K91148820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64863
GSE192870_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K84233365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1257
BRD-K61213827	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36032
piromidic acid-4575	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16118
SHSYSY+RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.843816
CV-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.77
CL-40	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.950195
reticular nucleus of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.047
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4893
RNF125	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14727
lingual gyrus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.889146
primary motor-sensory cortex (samples)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09946
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.56269
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.439
NEFH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44261
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.47738
DAOY	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69161
BRD-K19100834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2041
MCCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69236
LRRC58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94224
BDCA4+_DentriticCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.04537
Charcot-Marie-Tooth Disease	DisGeNET Gene-Disease Associations	1.0	null
PIWIL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29146
rnf2_20805357_u2os_osteosarcoma_lof_human_gpl570_gse23035	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.352506
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3171
REEP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05389
CBX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55518
BRD-K03911650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02605
C10orf95	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34634
SNX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69649
BRD-K73051782	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10895
RBM25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62707
BRD-K42776812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46499
AGO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.046
BRD-K02535446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55395
THOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11415
DHRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45432
CRCGN017_MCF10A.WT.HP_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.24635
ZNF786	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48806
SKLU1	CCLE Cell Line Gene CNV Profiles	1.0	1.56437
SNUC2A	Achilles Cell Line Gene Essentiality Profiles	1.0	1.11761
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3527
KMT5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78098
BRD-K34369474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14313
PCF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41587
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4325-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEATR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03876
GALT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62708
HSC3	CCLE Cell Line Gene Expression Profiles	1.0	1.56544
BRD-A82394575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03436
COLO201	CCLE Cell Line Gene Expression Profiles	1.0	2.0354
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42217
cinoxacin-5783	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MHHCALL3	CCLE Cell Line Gene Expression Profiles	-1.0	-2.57779
BRD-A20463452	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69766
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1791
SOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99377
IZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.854196
PMC11116544-41698_2024_606_MOESM6_ESM.xlsx-Sheet1-Supplementary_Data_4_Significantly_differentially_expressed_genes_between_TCGA-HNSC_patients_carrying_amplified_MYC_and_wild-type_MYC_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
Human - Lung v1 - L1 - Serous	HuBMAP Azimuth Cell Type Annotations	1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.959347
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.94514
CD101	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00597727
MPLKIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94046
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.20222
DMS-53	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
BRD-K54948591	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13144
BRD-K90111788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19448
GUCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4847
ZNF549	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22694
AGXT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47511
HH	GDSC Cell Line Gene Expression Profiles	1.0	1.59581
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051567
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27757
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.36396
Large latent transforming growth factor-beta complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.875
PTPN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56533
KMT2E	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00420469
Brain Lower Grade Glioma_LGG_TCGA-HT-A614-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SERTAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28462
BRD-K95591068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0881
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.68529
ZNF791	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77529
gibberellic acid-2910	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K55220938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55358
PMEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78691
SUPHD1	CCLE Cell Line Gene CNV Profiles	1.0	1.33129
ASXL1-24218140-BMDM-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K33597325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04615
liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.36187
VCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88274
PK-59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1041
SKIL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00583075
DARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59513
NCIN87	Achilles Cell Line Gene Essentiality Profiles	1.0	1.24743
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12302
CRCGN011_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.4689
ATIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56334
BRD-K92712671	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10327
Kidney Chromophobe_KICH_TCGA-KN-8436-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
C2BBE1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K80715600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36797
HUG1N	Achilles Cell Line Gene Essentiality Profiles	1.0	1.83949
merbromin-3700	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
mouth	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8921
colforsin-7055	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCIH2052	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.03671
ramifenazone-6097	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SEZ6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19089
WDR91	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.56371
BRD-K83544408	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15173
stratum lacunosum-moleculare of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.75426
TRAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19229
BRD-K03902845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71591
Brain stem	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
AM38	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.13018
BRD-K60132279	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35251
orbital frontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0361
mediodorsal nucleus of thalamus_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.933772
BRD-K64730221	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07786
RNF135	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71105
SRSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4571
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20X-01A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
isoetarine-2711	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SUDHL8	CCLE Cell Line Gene Expression Profiles	1.0	1.55329
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02414
BRD-K51791049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21414
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.45678
RBPJL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72889
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.955842
GPRC5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82693
nomifensine-2224	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H4C8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99858
496100283_PCx_probable Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.18007
GSE90552_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.65245
HHEX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27972
BRD-K40765512	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14625
NDUFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27036
Renal epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.406
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3358
BL461 (RBM14)	NURSA Protein Complexes	1.0	null
BRD-A23340824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52509
NatC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.531
A3KAW	CCLE Cell Line Gene Expression Profiles	1.0	1.74282
dexamethasone-123	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K42496940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15769
FBXO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4544
JUN	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K28299335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69959
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A3CJ-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skin	GTEx Tissue Gene Expression Profiles	1.0	2.03665
QGP1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.81436
SIDT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00626431
DSP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6551
SUDHL6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65114
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07986
CRCGN016_MCF10A.TP53.M_24H:L18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.75136
IRX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32525
TCEA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28581
BRD-K12866026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.04087
CRACR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02303
CRCGN017_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.65315
endopiriform nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.849213
TSPAN7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0063983
TMEM223	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58894
496100368_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.24879
CRCGN015_MCF10A.TP53.M_24H:O24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3886
ASXL1	ChEA Transcription Factor Targets	1.0	null
BRD-K78668110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52065
BRD-K15128331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82981
citalopram-4377	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K01022714	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36011
HL-7702 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.854
posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.90235
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC8017594-LSA-2019-00332_Table_S1_Table_12.xls-DCX-KD_LIS1-KD_DEGs-LIS1-KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GATA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.239
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_33_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.79312
SK-MES-1	GDSC Cell Line Gene Expression Profiles	1.0	1.5913
MROH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79293
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GV-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K55518911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03967
pyrantel-5088	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
beclometasone-3001	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
outer SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03205
BRD-K71755682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32197
MZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.991433
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.890616
N-acetyl-L-leucine-4622	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K97666659	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26704
AML193	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61602
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54K-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Wes	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.053
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9801
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.405
Saliva	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.546
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7101-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DCAF4L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51116
PSMB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62225
CORL24	CCLE Cell Line Gene Expression Profiles	-1.0	-1.91337
BRD-K21544408	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21351
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV1-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLM1	CCLE Cell Line Gene CNV Profiles	1.0	1.42274
FYTTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66816
SERF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5669
BRD-K53896147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63548
BRD-K30632097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04784
BRD-K96779993	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08852
496100574_HIP_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.66525
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.961951
CRCGN009_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21305
SYT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49345
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.736
cyclizine-2880	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RCN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20589
Prestwick-675-6042	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZNF451	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63515
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5939
SKMM2	CCLE Cell Line Gene Expression Profiles	1.0	2.08349
BRD-K28512751	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70121
TPMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57224
NOTCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86416
KIAA0930	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83791
BRD-K38969544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31053
TTLL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63108
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41N-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Beare-Stevenson cutis gyrata syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.155
BRD-K85722065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57782
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.54517
TRAPPC6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08408
ISGF3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.673
SKMEL31	CCLE Cell Line Gene CNV Profiles	1.0	1.81672
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78O-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K27352194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01573
CAMTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47344
TNNC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52374
HDQP1	CCLE Cell Line Gene Expression Profiles	1.0	1.43905
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ARTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01491
DCBLD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02665
SW837	COSMIC Cell Line Gene Mutation Profiles	1.0	null
harman-4584	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-S5-A6DX-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
METTL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84647
BRD-K54456668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.44641
GSE121319_1_v_0_gprc5a_human	RummaGEO Gene Perturbation Signatures	1.0	null
KIFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50637
CORL88	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5248
TMEM41B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77594
SNB19	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.94363
Rectum adenocarcinoma_READ_TCGA-AF-6672-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.954381
MYB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42898
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV2-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BLTP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17486
WDR5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63597
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22267
SKM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21141
TSHZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75582
GABRD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48147
BRD-K30551445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01618
BRD-K38519440	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90257
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.964978
BRD-K80733946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1181
Pancreatic adenocarcinoma_PAAD_TCGA-F2-A44G-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GPX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56446
STRA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8907
SB-202190-7054	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
superior rostral gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.883419
UMC-11	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
HCRTR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00591773
BRD-K26472648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11
BRD-K75845970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53658
TestisSeminiferousTubule	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.83683
BRD-K76748254	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1575
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
naloxone-4645	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
outer plexiform zone in extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.85259
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01001
SLC10A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87348
ZRANB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54555
methylbenzethonium chloride-3768	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K45138525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21002
BRD-K25757432	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05598
BRD-K11930946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19817
RAD23A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63294
NME3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59519
CDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37921
IFNAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89248
BRD-K87602457	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20317
TMEM187	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92098
CRCGN011_HEPG2_24H:J13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7385
PGBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3781
ITGB1BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99918
RMND5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71812
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.494
Integrin alphaIIb-beta3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.58
Germ cell nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.042
primary motor cortex (area M1, area 4)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17385
BRD-K97798118	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1254
CELSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58066
DCAF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47879
D-245MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.9241
Type 1 diabetes mellitus_Thymic epithelial cell_GSE11	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.01255
UPK3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89632
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VH-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GNA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7578
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4813-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K92978173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52998
pregnenolone-4218	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
496100457_TCx_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.68413
Pancreatic adenocarcinoma_PAAD_TCGA-PZ-A5RE-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
body of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06558
BRD-K78344913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24718
Respiratory system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.442
PMC9643473-Table1.xls-MAF_0_005-Gene_refGenecanonical_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
CTTNBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76967
BRD-K32472782	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56781
CRCGN013_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2865
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.876777
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.56217
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.887132
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2244
SEC23IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47641
C13orf42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42391
HILPDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39002
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27863
NCIH1184	CCLE Cell Line Gene Expression Profiles	1.0	1.49073
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.60853
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.867739
BRD-K85200795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01469
UGCG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82489
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.884304
Lung squamous cell carcinoma_LUSC_TCGA-96-7544-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M5-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.47379
Brain - Cerebellar Hemisphere	GTEx Tissue Gene Expression Profiles 2023	1.0	2.19567
MAPK14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6292
RBM15B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19351
TRIM41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89181
BRD-K56592061	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.77285
BRD-K63252672	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28661
BRD-K53821452	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05239
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30535
BRD-K87995704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0793
FBXL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03132
PGAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25147
BRD-K61742182	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22305
b82	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.774
RNF40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00259
BRD-A08778300	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24054
SPCS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7594
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.86772
COLO680N	CCLE Cell Line Gene CNV Profiles	1.0	2.31688
NCIH1666	CCLE Cell Line Gene CNV Profiles	-1.0	-2.49262
TPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62728
OXT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00401811
ARMC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67096
EKVX	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.06185
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3427-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DDX43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89325
BRD-K30973947	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52472
ASS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77886
kidney	GTEx Tissue Gene Expression Profiles	-1.0	-1.38034
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.40236
ARRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57688
bromocriptine-4604	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.839
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K98271666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23203
primary motor cortex (area M1, area 4)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17481
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78P-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SiHa	GDSC Cell Line Gene Expression Profiles	-1.0	-2.13291
PIGH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60558
BRD-K60701773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45029
BRD-K43108627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35093
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18593
BRD-K07557785	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52892
BRD-K64329997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06934
BEND4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4728
BRD-K47584662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43569
microbody	LOCATE Predicted Protein Localization Annotations	1.0	null
GM97	BioGPS Cell Line Gene Expression Profiles	1.0	0.982957
EFO21	CCLE Cell Line Gene CNV Profiles	-1.0	-1.98921
BRD-K83952475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15
496100442_PCx_possible Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.90067
RAB23	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0045097
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4875-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH929	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44473
BRD-K15931098	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37594
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.86355
BRD-K60834597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57383
BRD-K31602570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15969
PGAM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82824
POLR2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74357
CBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08332
PPP1R13B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36815
USF2	JASPAR Predicted Transcription Factor Targets	1.0	null
Head	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	3.151
BRD-K62463442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20672
496100352_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.08842
TGFBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75271
NANOG-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CLDND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9804
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3715
BRD-K72125659	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37456
PANX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56343
ZNF267	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47511
BRD-K62256869	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34162
BRD-K35196805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72485
BRD-K97692908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25963
ZNF655	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68124
WDR45B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61248
CBS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45109
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00407
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.87552
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.73602
BRD-K30171122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06646
ISG20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61431
SHC4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00697678
BRD-K88385836	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08377
VIPAS39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30656
CNPY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19823
SNU1076	CCLE Cell Line Gene CNV Profiles	1.0	1.41417
IPC298	CCLE Cell Line Gene Expression Profiles	-1.0	-2.08609
basomedial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17158
CRCGN017_MCF10A.WT.HP_24H:N18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.039
MZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00958
ODC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4065
alpha-estradiol-6169	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HESX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3511
HEBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08017
BYSL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.004521
BRD-K91980109	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55659
BRD-K08995282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.80207
flucloxacillin-5527	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ECI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69768
BRD-K29652917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69584
PNRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09139
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.888819
fastigial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.950457
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22896
PRSS50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89655
norcyclobenzaprine-4776	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
globus pallidus, external segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.21472
BRD-K37033753	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18751
cisapride-2443	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-IH-A3EA-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RGS13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00642592
BRD-K57748937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08716
CCDC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99633
dipyridamole-4656	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45652
G6PD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87404
NK-92MI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4985-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
UBE2E2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00468596
SCPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32212
TRMT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2267
BRD-K37356599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1309
BRD-K26127374	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03898
CDKN2AIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40793
inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.843615
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8741
charcotmarietooth	GeneRIF Biological Term Annotations	1.0	null
BRD-K15779027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02065
BRD-K55171585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65089
BRD-K90874005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72563
GLRX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24258
GSE150049_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SF295	Achilles Cell Line Gene Essentiality Profiles	1.0	1.31347
BRD-K85546819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30006
PHF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09595
BRD-K31836496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16653
ORMDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43218
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.24315
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7PW-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHST15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03008
BRD-K80877725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00016
BRD-K83143868	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24406
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.3254
BRD-K00086692	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8175
CLNS1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08206
NCI-H1993	GDSC Cell Line Gene Expression Profiles	1.0	1.42733
frontal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.33981
HEC1B	CCLE Cell Line Gene Expression Profiles	-1.0	-2.02494
Submucosal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.701
CHL-1	GDSC Cell Line Gene Expression Profiles	1.0	2.17453
BRD-K48052543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79936
BRD-K46308702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.058
Immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
JUN_01_164	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61602
FAM83D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54705
Brain Lower Grade Glioma_LGG_TCGA-S9-A89Z-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A118-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN013_HEPG2_24H:B17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0149
CLTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63012
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04141
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1725
BRD-K26852477	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3009
FERMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45007
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.91606
GNPNAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14977
CRCGN009_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.46276
SNIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47158
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Mad-Max complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.715
Multiple synostoses syndrome 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.481
HCC2218	CCLE Cell Line Gene Expression Profiles	1.0	1.43771
POLE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62631
Enamel caries	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.043
HEY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.341
BRD-K52551495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19735
LU65	CCLE Cell Line Gene Expression Profiles	1.0	2.61382
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.90888
IA-LM	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
sirolimus-4431	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MALME 3M	BioGPS Cell Line Gene Expression Profiles	1.0	1.07568
Pancreatic adenocarcinoma_PAAD_TCGA-FB-A5VM-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.44252
SELENOH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33247
NMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70284
NCI-H441	GDSC Cell Line Gene Expression Profiles	-1.0	-1.51067
KMS28BM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37358
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30631
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0706
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CH-01A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAP1LC3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71337
BRD-K70584304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14752
RM-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.465
CDK2AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48942
Bilateral renal aplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.257
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VE-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC35E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12272
LASP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38087
TAOK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94613
salivary gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
inferolateral temporal cortex (area TEv, area 20)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.869373
BRD-K66526269	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19829
BRD-K44307624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34829
molecular_function	GO Molecular Function Annotations 2015	1.0	null
PGLS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55631
LS1034	CCLE Cell Line Gene CNV Profiles	1.0	2.26989
AHCYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.347
CHMP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68321
TFCP2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86946
Pancreatic adenocarcinoma_PAAD_TCGA-2L-AAQA-01A-21R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.WT.HP_24H:M08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.16208
BRD-K75243062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59102
TNFSF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19886
BRD-K78837609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90116
FGFR3_knockdown_174_GSE41035	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.75898
PRMT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0032603
VTI1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94082
FAM98A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18569
tolmetin-4088	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCIH2029	CCLE Cell Line Gene Expression Profiles	-1.0	-1.7698
NCI-H2373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28119
hsa-miR-3920	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
BRD-K20525312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2697
SELENOV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8657
Gill arch	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.937
NANOS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56682
BRD-K28510065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31634
ZNF74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31935
gl1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.07
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053857
BRD-K67586245	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47914
FYN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25731
HCC70	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K29628221	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30505
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.71991
PHLDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41594
BRD-K54370483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26768
LOXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6972
striatum_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.843615
CALML6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33064
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.220152
BRD-K69437108	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57101
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
dorsolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.40236
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24093
BRD-K79709959	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19148
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13306
SA1-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
TPRG1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21875
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.4355
orphenadrine-4359	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DNAJC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51474
PIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52367
POTEE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14004
ZDHHC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31269
KIR2DL4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00357272
mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
CRCGN016_MCF10A.TP53.M_24H:H10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0143
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
KGN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SAYSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80623
BRD-K94962942	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11673
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.10083
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7922-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF630	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67049
BRD-K82224868	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1457
BALL-1	GDSC Cell Line Gene Expression Profiles	1.0	1.9252
BRD-K30589514	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0671
496100397_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.25844
BRD-K08658757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67902
GALNT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84871
globus pallidus, external segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.30799
BRD-K56884305	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41146
MZ in dorsomedial parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29654
BRD-K44309337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35133
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0688
BRD-K67665252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23039
DAB2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52695
ZR751	CCLE Cell Line Gene CNV Profiles	1.0	1.46953
hypoglossal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02965
inner CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25554
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039425
C11orf71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18014
H3K9me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07834
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.917302
salsolidin-2824	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PRKCG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73376
EEF1AKMT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73797
RELA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51309
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.368
PATU8902	CCLE Cell Line Gene CNV Profiles	1.0	1.61699
BRD-K78603273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44273
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11602
Rectum adenocarcinoma_READ_TCGA-AG-3725-11A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LS513	Achilles Cell Line Gene Essentiality Profiles	1.0	1.14748
PMC12619835-41467_2025_66007_MOESM13_ESM.xlsx-Sheet1-Basal_like_KLF5_peaks_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
CIAO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76395
CRCGN011_HEPG2_24H:I24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.42055
PKIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32443
KDM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19603
basal nucleus of meynert, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16405
indapamide-4335	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SG in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17844
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.16263
BRD-K40532221	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4884
MZ in posteroventral (inferior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.870656
LN18	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.54229
6-benzylaminopurine-2313	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K03205303	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09318
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.889784
SUP-M2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K38434557	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4516
CRCGN015_HEPG2_48H:F04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04501
HDAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52744
Leukemia, Adult T Cell_Blood monocyte_GSE10789	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	0.73923
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Nearest_Ensembl_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM256	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7303
MET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98701
molecular layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25845
guaifenesin-3897	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HAGHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48327
REST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84617
BRD-K87053028	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30834
SCARA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80312
ZNF614	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23718
RNF146	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71855
bufexamac-5090	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
496100478_HIP_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.84815
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.9123
orbital frontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27863
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10306
BRD-K62203376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20157
HPAFII	Achilles Cell Line Gene Essentiality Profiles	1.0	1.64986
beclometasone-4403	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PLAU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80031
ZXDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3455
CRCGN017_MCF10A.TP53.M_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.54488
BRD-K56437119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04529
BRD-K33438042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57633
C6orf89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44367
BRD-K38060656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01587
BRD-K60353472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5434
BRD-K85441584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10688
DDX55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04935
CAL-51	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DPH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59607
Acute Myeloid Leukemia_LAML_TCGA-AB-3007-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NatB complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.506
RT112	CCLE Cell Line Gene Expression Profiles	1.0	3.38363
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.56217
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.50102
PMC5817105-thnov08p0972s2.xls-SIX3-GeneName_SIX3	Rummagene Transcription Factor Associations 2026	1.0	null
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AGER	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2585
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.876015
zalcitabine-4215	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K53489056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23416
ZBTB7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73625
NCIH526	CCLE Cell Line Gene Expression Profiles	1.0	1.6987
BRD-K53619784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55285
ISL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31339
IARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73886
HL60	BioGPS Cell Line Gene Expression Profiles	1.0	1.42106
H2BC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77795
COLO783	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63685
ZNF580	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.4706
PHA-00745360-3827	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AKIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7062
CRCGN017_MCF10A.WT.HP_24H:J08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04885
ZBTB45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17395
PLOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53387
ABI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63373
CORL88	CCLE Cell Line Gene CNV Profiles	1.0	1.41952
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17406
SAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08863
hippocampus (hippocampal formation)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13688
SCYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03484
BRD-K27451531	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07007
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4382
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34083
BRD-K44932450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0089
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.42254
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.926995
BRD-K84988480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79592
MEOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5581
Rge	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.993
YPEL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95307
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040552
H3K27me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CLOCK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00424366
BRD-K20644549	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07879
ACBD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73878
CA4 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.28232
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
dimenhydrinate-5450	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HS939-T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TEAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1317
halofantrine-6509	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K97493608	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68246
LB2518-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
S100A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37387
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4346-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZC3HC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84653