association	dataset	threshold value	standardized value
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF225	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39023
GATA1	ChEA Transcription Factor Targets	1.0	null
OR2A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19321
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25893
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
EFHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62874
GSE224599_0_v_1_tfcp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PANC1005	Achilles Cell Line Gene Essentiality Profiles	1.0	1.08664
DAN-G	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-4730	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GSE174498,GSE174500_5_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GGTLC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63979
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.86627
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Autoimmune disease of skin and connective tissue	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.859
TAF1	ENCODE Transcription Factor Targets	1.0	null
BAG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59293
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VC-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HLA-C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97213
cingulate gyrus, retrosplenial part, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.31498
GNG14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14554
PMC4595011-pgen.1005555.s001.xlsx-BPTF_DOWN-regulated-Gene_name_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
CAPZA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.75392
E2F1-21310950-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_438_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
corresponding	GeneRIF Biological Term Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5587-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF416	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71222
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40934
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SETD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32074
FBXO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98298
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.8524
ATRFLOX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53413
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF687	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84001
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CA-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13938
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SNF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09243
BIN67	DepMap CRISPR Gene Dependency	1.0	6.73803
pair	GeneRIF Biological Term Annotations	1.0	null
anteroventral nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.956075
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.22267
CELF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29496
TFRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24084
hsa-miR-617	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
EBF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76455
FIGLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65021
GSE213588_10_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SUPT4H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94423
GSE107956,GSE107957_0_v_1_ythdf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
FBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41942
IFITM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47364
Generic Transcription Pathway	Reactome Pathways 2024	1.0	null
SMIM24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04497
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.86014
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-8635-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BICRAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.27205
GSE193157_0_v_1_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HSPA1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30301
Gene expression (Transcription)	Reactome Pathways 2024	1.0	null
HAND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39704
PMC4407272-elife06857s002.xlsx-501M_BRG1-MITF_ComDown-List-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
TMSB4X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83614
TMEM199	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68251
medial parabrachial nucleus,right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.828298
CTCF_GM13977_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1954	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.859658
UACC257	CCLE Cell Line Gene Expression Profiles	1.0	2.25032
PMC11192681-11033_2024_9703_MOESM1_ESM.xlsx-ZFP_genes_expression_vs_methyla-Relationship_between_C2H2-ZNF_gene_expression_and_DNA_methylation_ZKSCAN7	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.716
ABCA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42927
hsa-miR-4489	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
EMC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63943
PCYT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41208
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19635
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7325-01B-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Retinoic acid_SK-MEL-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.00892466
ASXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17847
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
primary auditory cortex (core)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.895357
PARP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25395
BICR 31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02612
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07346
SHISA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.432
Adrenocortical carcinoma_ACC_TCGA-OR-A5J2-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
protein alkylation	GO Biological Process Annotations 2015	1.0	null
SAC3D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55826
Lung adenocarcinoma_LUAD_TCGA-49-4490-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1473
ANKRD63	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0694
OE19	CCLE Cell Line Gene Expression Profiles	1.0	1.59906
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.64431
Brain Lower Grade Glioma_LGG_TCGA-FG-7643-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PDE6D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85547
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM263	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88813
PCOLCE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52266
Conventional osteosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.233
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.866987
BRCA1	JASPAR Predicted Transcription Factor Targets	1.0	null
CORL23	Achilles Cell Line Gene Essentiality Profiles	1.0	1.09953
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FGF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45021
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.6587
H3-3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00118
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EU-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-626	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KIAA0930	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06306
peptidyl-amino acid modification	GO Biological Process Annotations 2015	1.0	null
NCIH1915	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32208
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Dorsal nerve cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.671
BICR16	CCLE Cell Line Gene CNV Profiles	1.0	2.00672
RAB40AL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.38029
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054809
KCTD19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17345
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19632
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80K-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the hair	GWASdb SNP-Phenotype Associations	1.0	0.827983
histone methyltransferase activity	GO Molecular Function Annotations 2015	1.0	null
GSE213588_8_v_7_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7882-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC4A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24418
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4153
OV7	Achilles Cell Line Gene Essentiality Profiles	1.0	1.39005
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.11793
DDX60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98238
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51301
GSE152441,GSE152442_0_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TTI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65963
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TSPAN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75252
MZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.32164
BGC823	CCLE Cell Line Gene CNV Profiles	1.0	1.4357
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.18128
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.975186
Acute Myeloid Leukemia_LAML_TCGA-AB-2824-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4417	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67922
Brain Lower Grade Glioma_LGG_TCGA-HT-A74J-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZK-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07417
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.994064
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SET domain	InterPro Predicted Protein Domain Annotations	1.0	null
CHST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62905
LARP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12734
EP300	ENCODE Transcription Factor Targets	1.0	null
UACC812	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.932663
vestibular labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.70845
ZNF624	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76894
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XP-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3014
E2F6	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054807
REPIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09478
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6603
inner CP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09442
protein-lysine n-methyltransferase activity	GO Molecular Function Annotations 2015	1.0	null
CASD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29688
SP2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7101
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.947957
PL4	DepMap CRISPR Gene Dependency	1.0	3.12253
hsa-miR-3667-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3Y7-01A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE213588_10_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RPL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08194
Meiotic cohesin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.988
GSE150055_0_v_1_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
RAP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7047
KIJK	DepMap CRISPR Gene Dependency	1.0	3.22521
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28917
SLC25A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4549
TACC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27982
MESSA	CCLE Cell Line Gene Expression Profiles	1.0	1.52147
TAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ERBB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5018
PITX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9181
PBX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6818
CHD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41985
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00035
MKI67	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72482
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.0415
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12886
COL4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11009
BHMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27678
NHLRC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50583
496100575_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.4213
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.840646
DLX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73129
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.70673
FYN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25731
TOP1MT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7055
macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
Suntan	DisGeNET Gene-Phenotype Associations	1.0	null
GSE213588_10_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H1-10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14438
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.60385
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NFKBIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80646
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.9742
TSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04603
SP1	ENCODE Transcription Factor Targets	1.0	null
TOX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64595
VOPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28253
abnormality of the eye	GWASdb SNP-Phenotype Associations	1.0	1.96614
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RCM1	DepMap CRISPR Gene Dependency	1.0	2.7652
Lateral element	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.788
CBX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35893
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NN-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LGI4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47105
Lung adenocarcinoma_LUAD_TCGA-86-7713-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9647903-13100_2022_279_MOESM9_ESM.xls-Human_KRAB-ZFPs-Information_of_all_human_KRAB-ZFP_genes_ZKSCAN7	Rummagene Transcription Factor Associations 2026	1.0	null
MELHO	CCLE Cell Line Gene Expression Profiles	1.0	2.13558
S-Adenosylhomocysteine	HMDB Metabolites of Enzymes	1.0	null
H3K27me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01345
MYBL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5636
SYNDIG1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61782
Adrenocortical carcinoma_ACC_TCGA-OR-A5JI-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KP-N-YN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FEZF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91097
VCAP	Achilles Cell Line Gene Essentiality Profiles	1.0	2.24046
HTR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78976
WM2664	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51747
SPHK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77761
WASHC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53296
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.5962
UBE2O	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8098
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02727
ARHGEF39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79003
KALS1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.09579
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.018
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary immunodeficiency disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.859
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A6UF-01A-23R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SELENOK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71166
PMC4856960-supp_gkv1471_nar-01762-z-2015-File010.xls-Genes_5kb_E2F7_Hyp-gene_name_E2F7	Rummagene Transcription Factor Associations 2026	1.0	null
YIPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95901
NCI-H358	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SPI1	ENCODE Transcription Factor Targets	1.0	null
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-V1-A8WS-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39937
GABBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51576
RAMAC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26649
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27961
Inner ear vestibulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.077
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7472-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
germ layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.255234
SP4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU1544	DepMap CRISPR Gene Dependency	1.0	8.81647
PYGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15984
SHMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15462
UCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27677
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5835-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TGFB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42271
PRRG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05792
subgranular zone of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.909387
hsa-miR-4712-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
hsa-miR-3909	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
PMC11192681-11033_2024_9703_MOESM1_ESM.xlsx-ZFP_genes_expression_vs_methyla-Unnamed_26_ZKSCAN7	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH1944	DepMap CRISPR Gene Dependency	1.0	2.14977
USHBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78411
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A263-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7125-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YW-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU16	DepMap CRISPR Gene Dependency	1.0	2.53605
ZNF382	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27003
PLAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91263
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5187-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE123943_1_v_3_sox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TT2609-C02	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NENF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4804
ALX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43293
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3R5-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.93038
AR	ChEA Transcription Factor Targets	1.0	null
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.30782
769P	DepMap CRISPR Gene Dependency	1.0	2.65647
layer IIIu of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.466
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48337
LGI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39423
FASN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17242
STK11IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82033
TMEM9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28271
JHUEM1	DepMap CRISPR Gene Dependency	1.0	11.0241
Schizozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.538
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.84623
RAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.598
Smith-Magenis syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.161
RILPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21253
PNMA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73836
SRSF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5768
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.971164
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.949296
CTV1DM	DepMap CRISPR Gene Dependency	1.0	4.04073
organelle	GO Cellular Component Annotations 2015	1.0	null
zona incerta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.42552
PAWR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13426
RPL18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55627
hsa-miR-4713-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
184A1N4	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.554271
histone H3-K4 methylation	GO Biological Process Annotations 2023	1.0	null
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.911502
ancestors	GeneRIF Biological Term Annotations	1.0	null
peptidyl-lysine modification	GO Biological Process Annotations 2015	1.0	null
USP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0381
HCT 116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53174
H1-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1114
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F5-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OPM-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
chromosome	GO Cellular Component Annotations 2015	1.0	null
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.68417
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Infigratinib_SK-MEL-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0117969
ENTREP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31733
ZFYVE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99046
Perturb_1177_KD_RUNX1_ERP128097	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02727
ANKRD13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.59421
eGFP-HDAC8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SEPTIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2557
NUDT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68578
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.86568
non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.2796
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3319-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EN	DepMap CRISPR Gene Dependency	1.0	2.03547
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A3R1-01A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.42731
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5015
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF671	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42833
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34509
UBF1/2-26484160-CHIP-SEQ-HMEC-DERIVED-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
STAT3	ChEA Transcription Factor Targets	1.0	null
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.941989
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-8537-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9013128-NIHMS1795992-supplement-4.xlsx-501mel_ARID2_KO_Upregulated-Gene__name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
DCAF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51062
biological_process	GO Biological Process Annotations 2015	1.0	null
MGAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95382
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.889713
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A1JW-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC25A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86494
NCIH2291	CCLE Cell Line Gene Expression Profiles	1.0	1.88179
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KINGS1	DepMap CRISPR Gene Dependency	1.0	2.41423
Perturb_1167_KD_ETV6_ERP128093	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
ZNF628	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40601
KLHDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22813
SKMEL2	CCLE Cell Line Gene Expression Profiles	1.0	1.59178
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.69009
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATG4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94866
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7591-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02047
NCI-H1155	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5988-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SORL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5072
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ECHDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74593
SNUC1	CCLE Cell Line Gene Expression Profiles	1.0	1.51174
SP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATG16L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66705
KLF4-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HS936T	CCLE Cell Line Gene Expression Profiles	1.0	1.77679
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33131
PIWIL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29146
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.89457
JDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18501
paralogs	GeneRIF Biological Term Annotations	1.0	null
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9718
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
congestive heart failure	GWASdb SNP-Phenotype Associations	1.0	0.448022
CTCF_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PDZD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8817
TONSL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93496
FAM156B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02947
Barr body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.228
16207381-Table1Sa	GeneSigDB Published Gene Signatures	1.0	null
REPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65866
molecular_function	GO Molecular Function Annotations 2015	1.0	null
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
peptidyl-lysine trimethylation	GO Biological Process Annotations 2023	1.0	null
DNA binding	GO Molecular Function Annotations 2023	1.0	null
LRRC8D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43495
evolutionary	GeneRIF Biological Term Annotations	1.0	null
Pellicular membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.309
BHY	CCLE Cell Line Gene CNV Profiles	-1.0	-1.98096
MTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23855
ovary	GTEx Tissue Gene Expression Profiles	1.0	1.07935
GATM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54772
PLAAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65541
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YN-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZKSCAN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52683
SEL1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29064
regulation of transcription, dna-templated	GO Biological Process Annotations 2015	1.0	null
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TGFBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75271
TCEA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28581
SH3PXD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45031
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4985-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4778-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
ARHGEF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87788
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.9606
paracentral lobule, posterior part, left, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19079
divergence	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-378b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
HMX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57361
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EFE184	CCLE Cell Line Gene CNV Profiles	1.0	2.39944
MG63	CCLE Cell Line Gene CNV Profiles	1.0	3.27672
RPL37A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13134
NCIH2030	CCLE Cell Line Gene CNV Profiles	1.0	1.731
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.975186
EZH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82215
AP5B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31905
ZFHX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53867
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MLX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30642
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.975186
histone methylation	GO Biological Process Annotations 2015	1.0	null
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.69745
PSME3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97219
C9orf40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15602
PTPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24454
NCI-SNU-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Xenopus A6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.653
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hair disease	GWASdb SNP-Disease Associations	1.0	2.01742
ZFP69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89684
chromatin modification	GO Biological Process Annotations 2015	1.0	null
BCS1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86374
MAP4K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40374
A1BG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85948
JUN	JASPAR Predicted Transcription Factor Targets	1.0	null
CAOV3	CCLE Cell Line Gene Expression Profiles	1.0	1.98213
CORL95	CCLE Cell Line Gene CNV Profiles	-1.0	-2.28422
E2F1-21310950-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MCFD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82258
NCI-H1755	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A87Q-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lysine degradation	KEGG Pathways 2026	1.0	null
H2AC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.61338
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Set1C/COMPASS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.95
COLO-783	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.83684
central gray of the pons, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.67849
CRTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62024
AVL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37888
MYOZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.59066
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TU-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-515-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
NEDD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42472
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35058
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
SLAIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58844
Kidney Chromophobe_KICH_TCGA-KL-8332-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14691
GGCX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84393
Lung adenocarcinoma_LUAD_TCGA-64-5775-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RERFLCSQ1	CCLE Cell Line Gene CNV Profiles	1.0	1.73368
heart failure	GAD Gene-Disease Associations	1.0	null
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
medial subdivision of area 10	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19373
LOUCY	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44873
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39576
Generic Transcription Pathway	Reactome Pathways 2014	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-5963-02A-12R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DPCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88457
CORL51	CCLE Cell Line Gene Expression Profiles	1.0	1.36309
hsa-miR-4456	TargetScan Predicted Conserved microRNA Targets	1.0	0.085563
hsa-miR-4696	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5UN-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11455
SLC29A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44546
Lung adenocarcinoma_LUAD_TCGA-55-8085-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VPS29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47563
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKBR3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43526
DKK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60719
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.942111
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83V-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cochlear duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.7711
TBCEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85879
cellular component organization or biogenesis	GO Biological Process Annotations 2015	1.0	null
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
SRF	ENCODE Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29M-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21856
H3K27me3_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2318
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ALDH9A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57535
HDGF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02554
STRADB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19951
ADSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78001
hsa-miR-422a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
dorsolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04841
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2781
ZNF404	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13758
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GU-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHOX2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02817
regulation of nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
HIV Infections	HuGE Navigator Gene-Phenotype Associations	1.0	null
SMIM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24732
PMC4595011-pgen.1005555.s001.xlsx-MITF_DOWN-regulated-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
TE4	CCLE Cell Line Gene CNV Profiles	1.0	1.49014
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.86627
NSUN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49516
FAM229A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63719
TMEM44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83848
FLOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3857
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NKX6-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76716
CAL148	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64076
MDAMB134VI	CCLE Cell Line Gene CNV Profiles	-1.0	-1.83219
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8397
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055911
ACHN	CCLE Cell Line Gene CNV Profiles	1.0	1.35903
Cortical Lewy body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.207
LDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38167
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.506
MSH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19412
NCIH292	CCLE Cell Line Gene Expression Profiles	-1.0	-1.80375
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.723
BRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92459
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7693-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC364	Achilles Cell Line Gene Essentiality Profiles	1.0	1.60259
regulation of primary metabolic process	GO Biological Process Annotations 2015	1.0	null
SELENBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2134
Prostate adenocarcinoma_PRAD_TCGA-G9-6332-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cd86 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.642
after	GeneRIF Biological Term Annotations	1.0	null
NUDT12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68156
heart	GTEx Tissue Gene Expression Profiles	-1.0	-1.09795
CTCF-27219007-CHIP-SEQ-ERYTHROID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A44B-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.928873
MPST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16066
CST complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.769
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-common-common_genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_NB4_HL-60_and_Kasumi-1_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
uveal disease	GWASdb SNP-Disease Associations	1.0	1.56544
PMC11328671-jitc-12-4-s003.pdf-323-PRDM10_PRDM10	Rummagene Transcription Factor Associations 2026	1.0	null
TMBIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82525
SRSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49459
SMARCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35456
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cardiovascular	GAD High Level Gene-Disease Associations	1.0	0.293278
protein metabolic process	GO Biological Process Annotations 2015	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_481_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
LU-165	COSMIC Cell Line Gene Mutation Profiles	1.0	null
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22905
Perturb_234_KD_MITF_SRP048577	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
MT-ND4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12654
regulation of gene expression	GO Biological Process Annotations 2015	1.0	null
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15138
SNU840	DepMap CRISPR Gene Dependency	1.0	4.61237
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM168	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.966
C1orf52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43636
ZNF391	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33456
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28297
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.870773
NB17	DepMap CRISPR Gene Dependency	1.0	3.92142
SNU719	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47746
EPB41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53089
ECD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5192
CCNC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63023
hippocampus (hippocampal formation)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23279
UGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02426
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213588_8_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PCDHAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06615
BLOC1S6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00519
GRB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63242
GPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20819
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11C-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060268
CDHR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02044
C6orf62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65296
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HI-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-62-A46V-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3158-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
KO52	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61406
ZNF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12538
intracellular part	GO Cellular Component Annotations 2015	1.0	null
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.040758
Brain Lower Grade Glioma_LGG_TCGA-HT-8104-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41016
GSE167224,GSE168147_1_v_5_hnrnpk_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTR9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46435
GSE169205_3_v_7_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBED6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.72652
hsa-miR-3158-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
FDXACB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29642
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.870773
TTYH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64705
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
NCIH1437	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.32908
ALDH5A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11022
HCFC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
regulation of biosynthetic process	GO Biological Process Annotations 2015	1.0	null
HDAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11418
Finding Of Mean Corpuscular Hemoglobin	DisGeNET Gene-Phenotype Associations	1.0	null
CDK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69933
GABARAPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2442
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2J6-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral tuberal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.33448
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OL-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21003
MTA3	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A66S-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIK3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67045
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO684	DepMap CRISPR Gene Dependency	1.0	2.66359
FKBP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95318
SNU324	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56122
PUS7L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8546
ZR75B	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.03798
MKN74	CCLE Cell Line Gene CNV Profiles	-1.0	-2.00355
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.102997
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7248-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rostral subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.866806
Brain Lower Grade Glioma_LGG_TCGA-QH-A870-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
histone-lysine n-methyltransferase activity	GO Molecular Function Annotations 2015	1.0	null
HPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13422
GCAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20759
IZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09755
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A9WI-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ILVBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04153
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
regulation of rna biosynthetic process	GO Biological Process Annotations 2015	1.0	null
AGAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53959
RPSA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76554
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.866987
ANKRD30A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20448
GSE197850_4_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
CKLF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32368
nucleic acid binding	GO Molecular Function Annotations 2015	1.0	null
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01537
tuberomammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.72943
lateral hypothalamic area, tuberal region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.36093
RVH421	DepMap CRISPR Gene Dependency	1.0	2.08299
RWDD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45785
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8234
496100343_TCx_possible Alzheimer's disease_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03302
transferase activity, transferring one-carbon groups	GO Molecular Function Annotations 2015	1.0	null
FBXO45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48401
DHCR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31429
H4C15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66766
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1378
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.36514
D-247MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF550	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26623
HIRIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19264
POLR2AphosphoS5_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NYAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.54851
PMC6812029-mmc1.docx-7-ASH1L_ASH1L	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
S-Adenosylmethionine	MW Enzyme Metabolite Associations	1.0	null
Perturb_14761_KD_LATS1/LATS2_SRP345234	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.57244
NFIC::TLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4375
CAL27	CCLE Cell Line Gene Expression Profiles	1.0	1.82869
SCS214	DepMap CRISPR Gene Dependency	1.0	6.97839
SP1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BAG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81439
IL11RA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52129
POLR2A	ENCODE Transcription Factor Targets	1.0	null
NCIH3255	CCLE Cell Line Gene Expression Profiles	-1.0	-1.73061
Site of double-strand break	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.731
OCIAML2	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.541
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.942111
POMGNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91306
TYK-NU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q3-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hypotrichosis 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.404
IGR1	CCLE Cell Line Gene Expression Profiles	1.0	1.46618
ELL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15238
KDM4A	ENCODE Transcription Factor Targets	1.0	null
regulation of cellular macromolecule biosynthetic process	GO Biological Process Annotations 2015	1.0	null
EID2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.39032
FEM1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62015
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.12563
S-Adenosylhomocysteine	MW Enzyme Metabolite Associations	1.0	null
cutaneous photosensitivity	GWASdb SNP-Phenotype Associations	1.0	2.3243
PPP2R5E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01238
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of mammary gland_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
IPC298	CCLE Cell Line Gene Expression Profiles	1.0	1.8951
C1orf216	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04149
NDUFB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63739
TE1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7447
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.899624
rostral subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.881061
PPM1N	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7115
GPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37245
PGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00628
PLCB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45086
SMARCA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01711
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.896448
ARFIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61006
UBE2N	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33787
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CBLL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55711
MALT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17024
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MSN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17213
olfactory part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.964225
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Adrenocortical cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.785
S117	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49605
hsa-miR-526b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
ZIC5_01_284	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.5898
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5885-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PTMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26185
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PRRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03932
NUDT4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22283
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6155
OVISE	DepMap CRISPR Gene Dependency	1.0	10.4091
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.90826
FOXP1-21924763-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
EBC1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.07929
TUHR10TKB	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57209
PA-TU-8902	COSMIC Cell Line Gene Mutation Profiles	1.0	null
pontine raphe nucleus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.903141
COX7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97754
stratum lacunosum-moleculare of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21909
RAB22A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07979
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
59M	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34353
Rectum adenocarcinoma_READ_TCGA-EI-6513-01A-21R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
eye and adnexa disease	GWASdb SNP-Disease Associations	1.0	0.356657
SETDB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28233
CDK16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62033
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
hsa-miR-378i	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
ZNF143	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53936
Lung adenocarcinoma_LUAD_TCGA-86-7955-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE229309,GSE229314_4_v_1_elavl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Azoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.337
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PDS5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20947
ACTRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4148
SIHA	CCLE Cell Line Gene CNV Profiles	1.0	2.07128
Integumentary system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.716
496100402_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.31477
FOXI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52635
Gametocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.278
E2F6_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HIVEP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62972
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SLC31A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49736
PGGT1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23757
hsa-miR-654-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
MAX	ENCODE Transcription Factor Targets	1.0	null
Perturb_12666_OE_GFP_SRP308919	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.73077
FAM83E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85374
layer III of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11341
HINFP	JASPAR Predicted Transcription Factor Targets	1.0	null
SVIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17533
P300-27058665-CHIP-SEQ-ZR-75-30CELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
VZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.29284
RAB31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90065
PMC4856960-supp_gkv1471_nar-01762-z-2015-File012.xlsx-GO_common_7H-HIF1_chip-Common_elements_in_chip7h_and_chip_hif1_2530_official_gene_symbols_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
PA2G4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11414
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
rostral (anterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.3781
TCEAL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55393
H3K27me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-8179-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24337
MZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.92455
methyltransferase activity	GO Molecular Function Annotations 2015	1.0	null
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAP3K20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34614
ZC3H13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78506
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ATRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02826
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
FBLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5269
organelle organization	GO Biological Process Annotations 2015	1.0	null
H4C5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.57907
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RUNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56027
MAU2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8282
Ventral nerve cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.784
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.975186
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B5-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE162892_4_v_5_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
ELF1	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SP2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZMYM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80734
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
regulation of macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
SUV39H2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85478
MRPL34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30043
HOXB7-26014856-BT474-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H2AB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6314
ARL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33745
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1476
nucleus	GO Cellular Component Annotations 2023	1.0	null
Antler	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.989
MRPL47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5837
ANKRD50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83032
NFIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85895
CTCF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.903509
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.942111
LANCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10963
primary motor cortex (area M1, area 4)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.927036
IMR32	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68411
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.048356
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NG-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
positive regulation of meiotic nuclear division	GO Biological Process Annotations 2023	1.0	null
PBX3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.05954
TRIM59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71671
GSE159893_2_v_0_genistein_human	RummaGEO Drug Perturbation Signatures	1.0	null
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.871843
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.152
ODAD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86476
Pancreatic adenocarcinoma_PAAD_TCGA-OE-A75W-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FASLG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10088
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55239
JHOS-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OVMANA	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33591
Autoimmune disease of musculoskeletal system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.859
regulation of macromolecule biosynthetic process	GO Biological Process Annotations 2015	1.0	null
TIGD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15069
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4656
ALS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54206
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4FC-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-A493-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TV-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.416
SLC2A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3858
JHOS4	CCLE Cell Line Gene CNV Profiles	1.0	1.63656
E2F1	JASPAR Predicted Transcription Factor Targets	1.0	null
KIAA2026	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89814
amygdaloid complex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.87815
Lung adenocarcinoma_LUAD_TCGA-55-7914-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
protein-lysine N-methyltransferase activity	GO Molecular Function Annotations 2025	1.0	null
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.844178
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.5029
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ROCK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2729
SK-MM-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SOX21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27088
Integumentary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.859
496100458_FWM_no dementia_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.44829
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3964
YDJC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2559
VAV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08002
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62064
ZNF836	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66064
CHTF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76378
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
Sarcoma_SARC_TCGA-IS-A3K6-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU1076	CCLE Cell Line Gene Expression Profiles	1.0	1.73049
TGFBRAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75663
SLC35E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41551
PGAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91853
prdm7	GeneRIF Biological Term Annotations	1.0	null
DNAJC19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0572
SMAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3262
GSE165334_2_v_0_dabrafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXP1-21924763-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-3936	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
RMUGS	DepMap CRISPR Gene Dependency	1.0	3.45563
GSE174498,GSE174500_5_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
internal segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1232
LIME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68582
medial mammillary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.4135
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
JHESOAD1	CCLE Cell Line Gene CNV Profiles	1.0	1.37974
PBX3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RANGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.36075
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09003
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.876026
outer CP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.953233
BT16	DepMap CRISPR Gene Dependency	1.0	5.47958
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VJ-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.082
SMIM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61262
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5699-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.839
TMOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11651
LCORL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23731
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_1181_KD_CBFB_ERP128097	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Prostate adenocarcinoma_PRAD_TCGA-J4-A83I-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NTMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45184
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ITPR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50531
Nrf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	60.6299
SP1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NME2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09511
outer SZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11975
neuroepithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.796874
TIMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66638
RB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40629
APOL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40181
SNU886	CCLE Cell Line Gene Expression Profiles	-1.0	-1.75163
HEATR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77979
UBXN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1045
SIRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00861
JHH7	CCLE Cell Line Gene Expression Profiles	-1.0	-2.69021
SK-CO-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GDE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.78109
MTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61078
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AUTS2-25519132-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
lateral habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.32138
SPI1_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6472-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27921
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.018
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC25A25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42346
layer VI of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.43474
MEWO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
KNS81	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.23735
GLI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44036
Brain morphology (MOSTest)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.4699
SLC38A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.54366
MBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61381
IKZF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09307
supraoptic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.836072
Heart primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.795
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1352
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07499
PLEKHG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45158
SRSF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11042
Ookinete	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.195
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
spiral organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.794375
Autoimmune disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.859
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.33845
ZNF257	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97295
HLA-DOA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84828
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4860-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Male urethra	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.564
PMC4595011-pgen.1005555.s001.xlsx-MITF_DOWN-regulated-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3004
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11548
RAB5IF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09202
SNGM	DepMap CRISPR Gene Dependency	1.0	2.19724
supramammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19955
URGCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5021
ZNF876P	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93129
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sensory system disease	GWASdb SNP-Disease Associations	1.0	0.31713
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
paracentral lobule, posterior part, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.833235
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LIAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59108
AASS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4093
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39937
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3650	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
caudal (posterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06289
PMC4407272-elife06857s002.xlsx-501M_BRG1-MITF_ComDown-List-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
pyramidal cells of rostral CA4	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.60984
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46258
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7952
single	GeneRIF Biological Term Annotations	1.0	null
Vitiligo	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.859
RPL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90445
SP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4595011-pgen.1005555.s001.xlsx-BPTF_DOWN-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
piriform cortex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.970726
SOX2-21211035-LN229_GBM-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R8-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TATDN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1014
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51666
USP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23107
TMEM59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09076
THTPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6788
CTCF_HCT116_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39937
SG in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08445
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSTCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97284
hsa-miR-4469	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.60841
CCNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15675
NGP	DepMap CRISPR Gene Dependency	1.0	2.55457
SKMEL28	CCLE Cell Line Gene Expression Profiles	1.0	3.35844
hsa-miR-532-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
CHCHD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40937
BT20	CCLE Cell Line Gene CNV Profiles	1.0	1.55893
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	83.6657
hsa-miR-4768-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE213588_10_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Heart Failure	dbGAP Gene-Trait Associations	1.0	0.008348
UTX-26944678-CHIP-SEQ-JUKART-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NPFF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91819
ZDHHC23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32207
JAZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90463
ASB16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58364
MIGA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4327
MAZ	ENCODE Transcription Factor Targets	1.0	null
IL17RC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60218
TFAP2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50091
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7459
MST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3763
SLC31A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96938
ENTPD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65699
MAFG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.74579
NCIH1155	CCLE Cell Line Gene CNV Profiles	1.0	1.44527
heterocyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
SENP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65743
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
PDGFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88412
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.905167
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Male infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.293
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30426
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01081
Lung adenocarcinoma_LUAD_TCGA-55-8094-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCDC93	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.72687
posteroventral (inferior) parietal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16891
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CMC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07435
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZFY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93823
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SP1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACLY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37287
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.990609
red hair	GWASdb SNP-Phenotype Associations	1.0	0.844241
DNAJB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60007
Rectum adenocarcinoma_READ_TCGA-AH-6549-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02488
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Nearest_Ensembl_1_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1QA-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-69-8255-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
SIRT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1998
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
ATCAY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25933
pineal gland	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.910062
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
central part of CEl	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.935787
FBXO28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2558
Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7GZ-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.889813
NT5C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09917
Adrenocortical carcinoma_ACC_TCGA-OR-A5J1-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TTC38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46131
MBIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26584
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JG-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Olfactory placode	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.752
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7425
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7341
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-335-ZNF469_ZNF469	Rummagene Transcription Factor Associations 2026	1.0	null
ALG10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44918
precuneus, right, superior lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.918779
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RT-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2143
GSE213588_8_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAF-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
STAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22346
GATA1-19941826-K562-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
YY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.78275
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19152
KDM4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37368
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DSEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63828
FUT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71531
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.30505
ITPRIPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8571
Carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.018
DNAJB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16232
ATF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45564
nucleus of the diagonal band, left, horizontal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.905181
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF692	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96087
Rectum adenocarcinoma_READ_TCGA-EI-6881-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92685
POC1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51569
GSE162892_4_v_0_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.22984
ESRRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38978
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GA10	CCLE Cell Line Gene CNV Profiles	1.0	2.2396
hsa-miR-3176	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
ZC3H15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31022
posterior (caudal) superior temporal cortex (area 22c)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.67563
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ENPP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67891
DNPEP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38313
GSE169205_0_v_6_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20925
MUC3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88505
JPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21551
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IX-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE-510	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3C7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19464
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RT112	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.29634
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6736
posterior (caudal) superior temporal cortex (area 22c)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.828586
Adrenocortical carcinoma_ACC_TCGA-OR-A5LC-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	97.8962
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.942111
CYFIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57434
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventral tegmental area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.27098
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.934671
ACTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78616
iris disease	GWASdb SNP-Disease Associations	1.0	2.01742
PMC4909395-elife-13964-supp1.xlsx-Sheet1-Supplementary_file_1_shRNA_screen_hits_selective_to_ERG-positive_prostate_cancer_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
S100A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34179
RBM18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60138
histone H3K4 methyltransferase activity	GO Molecular Function Annotations 2025	1.0	null
TRO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61273
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCOA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4769
reticular nucleus of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.50423
NIHOVCAR3	DepMap CRISPR Gene Dependency	1.0	4.49333
SPSB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54063
ASIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0026
hsa-miR-4276	TargetScan Predicted Conserved microRNA Targets	1.0	0.212286
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5555-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EIF4G3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13021
KLF16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42494
PRM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55882
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.959317
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3471-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FU97	DepMap CRISPR Gene Dependency	1.0	2.27144
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-2355-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
SCMCRM2	DepMap CRISPR Gene Dependency	1.0	2.61264
MT-ND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.7337
LK2	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.57249
cellular component organization	GO Biological Process Annotations 2015	1.0	null
CLDN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25381
Utricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.347
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01656
HDAC2	ENCODE Transcription Factor Targets	1.0	null
SKNDZ	DepMap CRISPR Gene Dependency	1.0	3.06291
FUS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56861
Lung adenocarcinoma_LUAD_TCGA-64-5778-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Up_bins-Up_bins_gaining_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
TBX22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00308
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30251
regulation of cellular biosynthetic process	GO Biological Process Annotations 2015	1.0	null
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.73629
RAD52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6474
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HDAC6	ENCODE Transcription Factor Targets	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14854
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.8532
NCI-H2122	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PBX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62047
Macrogamete	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.763
APEX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46298
ZNF547	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3547
ZHX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27212
FAAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20576
SH10TC	CCLE Cell Line Gene Expression Profiles	-1.0	-3.46209
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
non-membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
THEM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13044
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZNF222	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36253
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.72637
stratum radiatum of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39001
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6959
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39636
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09358
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Gene_Name_1_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
ATPAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60504
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD4_01_119	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.19
RAD51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93168
ITM2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2565
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29N-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMAD5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.366
UBE3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96452
histone lysine methylation	GO Biological Process Annotations 2015	1.0	null
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-NB4-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_NB4_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
event	GeneRIF Biological Term Annotations	1.0	null
CCNQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80697
GSE210476_2_v_7_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.5411
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_17_KD_HEK293-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
EIF4E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94369
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superior occipital gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.955956
WSU-DLCL2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.636
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.25614
NUDT14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33686
binding	GO Molecular Function Annotations 2015	1.0	null
U118MG	CCLE Cell Line Gene Expression Profiles	-1.0	-2.66216
SNU-719	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.928873
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7225
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12864_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pedunculo(pontine) tegmental  nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.60332
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.967458
Nephrotome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.668
MGAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21506
protein methylation	GO Biological Process Annotations 2015	1.0	null
olfactory tubercle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.860013
Basal cell carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.716
MAPRE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.38456
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16115
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ANXA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66846
SAP30	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81711
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1438
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.46224
ZNF425	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09409
transferase activity	GO Molecular Function Annotations 2015	1.0	null
HS578T	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.40263
496100580_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01911
KCNQ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40428
hsa-miR-548q	TargetScan Predicted Conserved microRNA Targets	1.0	0.088999
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EL-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057148
ZNF365	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67613
PSAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25865
Acute Myeloid Leukemia_LAML_TCGA-AB-2897-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SHH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52199
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU520	CCLE Cell Line Gene Expression Profiles	-1.0	-1.88445
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4474-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
VCAP	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59447
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PBX3	ENCODE Transcription Factor Targets	1.0	null
KU1919	CCLE Cell Line Gene CNV Profiles	1.0	1.46766
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
FOXM1-26100407-CHIP-SEQ-HEK293-FLP-IN-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
NAPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03538
NCIH322	CCLE Cell Line Gene CNV Profiles	1.0	2.47579
TEAD4_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RC3H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55322
HNRNPA2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47804
ZBTB14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59567
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.8998
Cancer of the testis_Testis_GSE1818	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.1549
GPR161	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77095
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RABEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32581
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05241
Ikzf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.4159
SERINC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59355
supramarginal gyrus, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.910926
PMEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78691
HL-60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5176
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.467
HAGH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81742
PREP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98091
Lung squamous cell carcinoma_LUSC_TCGA-21-1082-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FMR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24653
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
melanocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.649749
hsa-miR-3170	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GCNT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0135
GPSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72494
PHF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55349
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Connective tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.859
regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
PGR-26153859-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
Dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
SP1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0019
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.148297
GSE123943_2_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZDHHC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64083
LKAAEAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52222
IRF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40249
Lung squamous cell carcinoma_LUSC_TCGA-NK-A5D1-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RTN4RL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36192
SCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95526
SP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.836736
caudal putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28675
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
outer CP in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.51137
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PML	ENCODE Transcription Factor Targets	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8428-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12756
GSE245778_1_v_0_runx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-378e	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
SYF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47305
ARTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20042
MPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72316
UBQLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40729
CTCF_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM200B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36752
CAMKV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26062
STARD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59099
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.044
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
s-adenosylmethionine-dependent methyltransferase activity	GO Molecular Function Annotations 2015	1.0	null
infection	GAD High Level Gene-Disease Associations	1.0	0.293278
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70M-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
THYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87374
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869632
CENPQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82082
NMRK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62739
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
inner ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.660304
CP66-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4769-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
ZNF169	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12441
RNF166	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.10858
utricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.38367
S-Adenosylmethionine	HMDB Metabolites of Enzymes	1.0	null
parolfactory gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.65274
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TCF21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81716
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04108
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.51406
Adrenocortical carcinoma_ACC_TCGA-OR-A5JS-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lysine n-methyltransferase activity	GO Molecular Function Annotations 2015	1.0	null
496100615_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.32779
SP2_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CCDC85C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2567
ZDHHC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96565
cellular_component	GO Cellular Component Annotations 2015	1.0	null
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.33667
A549	CCLE Cell Line Gene Expression Profiles	1.0	1.56989
PDLIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09859
BEND5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51535
MZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30315
Lung adenocarcinoma_LUAD_TCGA-55-7570-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0023
EFO-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Hep-G2/2.15 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.592
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66063
DHX57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67382
TP53RK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03689
PMC13137955-ijbsv22p4243s2.xlsx-Sheet1-hTFtarget_E2F3_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45794
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ARMCX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99612
SETD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57249
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FAM20B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84517
PMC3303130-NIHMS40463-supplement-4.xls-KamKwaMuk_AA_differences-human_geneID_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CDK13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03041
DLG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88401
UBXN2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54147
SPATA20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96548
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5397
TMPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47055
NR2E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15938
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.96037
DYNC2I1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55305
KYSE-270	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-4461	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
EBF1	ENCODE Transcription Factor Targets	1.0	null
NT5DC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87566
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062312
Synaptonemal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.26
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GRHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9817
SMG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65944
PLCXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31221
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
WHSC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
close	GeneRIF Biological Term Annotations	1.0	null
Classical Lewy body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.423
SP4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.64461
BLOC1S2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3038
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.9655
ES-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04092
GK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71186
DYRK1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67181
HUTU80	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.54475
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SSXRD motif	InterPro Predicted Protein Domain Annotations	1.0	null
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48337
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.8105
RNF19B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66681
IMMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4008
TAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49558
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Synaptonemal structure	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.254
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
SUM102PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.28562
HCFC1	ENCODE Transcription Factor Targets	1.0	null
C14orf93	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86564
CTCFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7947
hsa-miR-378d	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
ZFYVE16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34811
GSE174498,GSE174500_5_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TEKT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92586
H3K27me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Seminiferous epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.751
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.11637
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14551
SH3PXD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2961
regulation of nucleobase-containing compound metabolic process	GO Biological Process Annotations 2015	1.0	null
CNNM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34357
ATP8B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61696
GSE162892_4_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1IB-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
FAM110C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00903
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.35955
SFMBT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1161
LHX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96605
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
subthalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.49072
NCI-H1915	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7632
MARCHF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98287
SCMH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12993
Adrenocortical carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.3
SNU685	CCLE Cell Line Gene Expression Profiles	-1.0	-1.80939
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-6846-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.78566
H3K27me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13217
Lung adenocarcinoma_LUAD_TCGA-78-7167-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3622
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRINP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23236
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.7018
CREG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56124
CYP2S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15219
IPMK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28509
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SELENOT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72902
NALM-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0832
LN18	CCLE Cell Line Gene CNV Profiles	1.0	1.67338
HMC18	CCLE Cell Line Gene Expression Profiles	1.0	1.54249
CNPPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52577
ZNF644	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46021
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MARK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32543
HSDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56883
Brain Lower Grade Glioma_LGG_TCGA-P5-A736-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TSPAN14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40616
KYSE520	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
WDR13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77845
HAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40105
GAL3ST3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20009
ZNF770	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52011
FZD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83075
HSPA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66477
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JM-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.899624
MV411	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.10507
VZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02164
Osmiophilic body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.147
C99	DepMap CRISPR Gene Dependency	1.0	3.37659
D502MG	DepMap CRISPR Gene Dependency	1.0	3.17142
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.73673
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
GRPEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37587
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
Skin cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.716
cellular protein modification process	GO Biological Process Annotations 2015	1.0	null
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051696
496100587_FWM_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.03706
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.927
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.705
SEMA6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41772
PBX3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
covalent chromatin modification	GO Biological Process Annotations 2015	1.0	null
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
methylation	GO Biological Process Annotations 2015	1.0	null
FOXR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82707
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.90053
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NRF1	ENCODE Transcription Factor Targets	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.845325
ZNF253	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21886
IOMMLEE	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.13021
Apicoplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.804
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.977
YWHAE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79824
VPS37B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50124
UBE2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39395
UBR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09696
hsa-miR-3612	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE169205_0_v_1_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.297
cellular macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
primary motor cortex (area M1, area 4)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.824547
PHF8	ENCODE Transcription Factor Targets	1.0	null
PFDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91072
H3K27me3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UMUC14	DepMap CRISPR Gene Dependency	1.0	2.53218
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.207
macromolecule modification	GO Biological Process Annotations 2015	1.0	null
UMUC16	DepMap CRISPR Gene Dependency	1.0	2.41094
ARL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05959
TASK1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of skin morphology	GWASdb SNP-Phenotype Associations	1.0	0.824011
Rosacea symptom severity	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.6
SCYL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07263
Condensed nuclear chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.091
PMC7857731-elife-63093-supp1.xlsx-DEG_MITF-X6vsEV-SkMEL28-Unnamed_1_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Melanoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.992
Hatching gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.757
BC3C	CCLE Cell Line Gene CNV Profiles	1.0	1.39505
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB361	DepMap CRISPR Gene Dependency	1.0	2.25193
SGPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26568
KDM2B-26808549-CHIP-SEQ-SIL-ALL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ACCMESO1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60938
caudal presubiculum (postsubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.57163
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0095
OVTOKO	DepMap CRISPR Gene Dependency	1.0	5.26775
generated	GeneRIF Biological Term Annotations	1.0	null
NAP1L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5976
abnormality of cardiovascular system physiology	GWASdb SNP-Phenotype Associations	1.0	0.068759
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.93001
OVMANA	CCLE Cell Line Gene Expression Profiles	1.0	2.4727
XY body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.539
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.871483
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-A6UM-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NRF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28917
duplication	GeneRIF Biological Term Annotations	1.0	null
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.975186
TP73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22411
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.87022
cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
Perturb_14764_KD_LATS1/LATS2_SRP345234	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.31607
macromolecule methylation	GO Biological Process Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-8070-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-DT-5265-01A-21R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.4091
ZNF302	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4329
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R7-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0879
GOLGA6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38285
histone modification	GO Biological Process Annotations 2015	1.0	null
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-CA-04-2009(H1N1)_12Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.32055
hsa-miR-4713-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.123298
CTCF	ENCODE Transcription Factor Targets	1.0	null
PRPF40A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1541
SYT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83302
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.257
ZBTB47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02154
TPRX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.804
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.3249
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.649
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5451-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-378f	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
ZBTB17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6242
REH	CCLE Cell Line Gene Expression Profiles	1.0	1.82109
recent	GeneRIF Biological Term Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A461-01A-41R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
planum polare, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04298
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11455
HOUAI	DepMap CRISPR Gene Dependency	1.0	4.33703
ZNF292	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28047
Saccule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.737
HCA-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5176
UNC13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23932
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.890133
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
protein-lysine N-methyltransferase activity	GO Molecular Function Annotations 2023	1.0	null
SOX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33137
GINS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83189
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.870773
UROD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66679
lateral parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.924979
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MZ in dorsomedial parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.48319
RPRD1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33586
PMC6424098-mmc5.xlsx-CEBP_Binder-Gene_names_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
YAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40189
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
HPS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15205
red nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07685
SG in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09871
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TNRC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84361
TMEM256	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62057
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-5326-01A-01R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01287
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9062
DDB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48121
IRF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17794
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.62378
PLB985	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7141
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48337
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.91233
NAGK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52559
SNU869	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52611
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5K6-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRGBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17353
GLIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6619
FAM120B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78916
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAPAN1	CCLE Cell Line Gene CNV Profiles	1.0	1.75759
abnormality of the integument	GWASdb SNP-Phenotype Associations	1.0	0.480859
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.29598
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-378h	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
MDAMB361	CCLE Cell Line Gene CNV Profiles	1.0	1.73688
MLLT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89275
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE213588_8_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH1048	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58224
Lung adenocarcinoma_LUAD_TCGA-78-7155-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.59668
RAB3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58543
positive regulation of DNA recombination	GO Biological Process Annotations 2023	1.0	null
DNAJC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58217
RGS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.77238
MALSU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87227
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZNF865	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99835
hsa-miR-4308	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
anterior (rostral) cingulate (medial prefrontal) cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17304
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GL-06A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27759
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1405
suggests	GeneRIF Biological Term Annotations	1.0	null
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.00807
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20039
ZNF165	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80365
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.904572
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18377
SNUC1	DepMap CRISPR Gene Dependency	1.0	2.54283
KLF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21444
CTNNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84713
TBC1D24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55832
RNF38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90731
SIN3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79896
M059K	CCLE Cell Line Gene Expression Profiles	1.0	1.46193
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4909989-ncomms11840-s2.xlsx-down-regulate-TEAD4-S_YAP_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
GLI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.2686
REH	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37162
Gene Expression	Reactome Pathways 2014	1.0	null
LANCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79341
LHX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16263
IZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.916113
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9116
SPTSSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3408
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.358
CHUK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93533
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.49114
HOXB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34555
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ESS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90323
positive regulation of reciprocal meiotic recombination	GO Biological Process Annotations 2023	1.0	null
NID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80597
MAPK8IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01134
Brain Lower Grade Glioma_LGG_TCGA-CS-6188-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.990135
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45Z-01A-21R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-16q24_3_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
ZBTB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02947
GSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6011
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10006
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13447
NOL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.9248
FGD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96266
NDUFS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38609
CTCF_keratinocyte_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.866987
ACVR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26718
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
UBL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48348
TE441T	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41405
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TP53_01_10	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.6163
SHOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15622
NLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63227
L-363	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CNOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06211
496100312_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.66197
KLK13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60687
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NUDT22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46131
Kidney renal papillary cell carcinoma_KIRP_TCGA-KV-A74V-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071178
PML_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HSD11B1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08286
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.550106
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11908325-media-2.xlsx-Table10_MR-Unnamed_2_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
SP1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23693
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.866987
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19C-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2218	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47461
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.859
ALKBH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49079
TOM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92548
subcallosal cingulate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.921584
SNU398	CCLE Cell Line Gene CNV Profiles	1.0	1.34407
MS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HSPA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62064
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11455
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUM-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
single-organism organelle organization	GO Biological Process Annotations 2015	1.0	null
Edinger-Westphal nucleus (accessory oculomotor nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35297
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053248
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CHST3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65368
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5736
nucleus	GO Cellular Component Annotations 2015	1.0	null
SOX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5679
OGFOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53959
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13115
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55129
RNF168	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59497
OSBPL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5914
Perturb_1182_KD_RUNX1_ERP128097	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	18.1367
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-HL-60-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_HL-60_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
NEMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.52002
RC3H2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55941
FAM167B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50122
SPRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90691
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
metabolic process	GO Biological Process Annotations 2015	1.0	null
IGROV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8313
SLC39A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92257
histone H3K4 methyltransferase activity	GO Molecular Function Annotations 2023	1.0	null
PMC3921136-CIN-13-2014-021-s001.pdf-158-PRDM4_PRDM4	Rummagene Transcription Factor Associations 2026	1.0	null
MAN1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7068
TCCSUP	CCLE Cell Line Gene Expression Profiles	-1.0	-1.68985
UFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82697
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54E-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
CARHSP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15493
hsa-miR-4780	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.76895
CLTC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36805
ZSCAN31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30356
KHK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44642
CBX3	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-4299	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
SW48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KDM5B	ENCODE Transcription Factor Targets	1.0	null
SP4	ENCODE Transcription Factor Targets	1.0	null
Autosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.322
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01855
PCBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2233
histone H3 methyltransferase activity	GO Molecular Function Annotations 2025	1.0	null
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.323
LYSET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15934
TNFAIP8L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77234
POLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67247
TCF12	ENCODE Transcription Factor Targets	1.0	null
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066412
TRIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05181
colo824	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.903
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.73376
ATP5PF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46193
ZNF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89731
UPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93948
NRTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38062
PMC4889920-supp_gkw096_nar-03505-x-2015-File018.xlsx-Target_genes_per_GO_class-HKR1_ZNF875	Rummagene Transcription Factor Associations 2026	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.102027
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5438
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
AU565	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.722534
GSE152699,GSE152723_3_v_2_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6HZ-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-N-DZ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.980789
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C22orf39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80114
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RS-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.869
TRIM54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7385
MBD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82097
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-52-7809-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33007
ZNF777	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3612
TUT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04762
SKMM2	CCLE Cell Line Gene Expression Profiles	1.0	1.37354
NDUFS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37688
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-1083-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
MARCKS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27275
CJUN-26792858-CHIP-SEQ-BT549-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
496100418_TCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.23125
ABI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36399
NARF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4741
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
CREB1-26743006-CHIP-SEQ-LNCAP-ABL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-NF-A4WU-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CHMP4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22219
cellular process	GO Biological Process Annotations 2015	1.0	null
BRSK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90723
YBEY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6745
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
FASTK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18905
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KLHL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33318
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.018
Skin disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.859
CHP212	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49229
CLN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.12741
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
protein modification process	GO Biological Process Annotations 2015	1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
CCNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.74025
lateral mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.34524
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9025
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_17_KD_HEK293-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SNAI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5963
TMTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07501
LDOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34093
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PDF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.46588
hsa-miR-663b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.9158
Brain Lower Grade Glioma_LGG_TCGA-HT-8010-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
UCMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89114
NDUFS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87466
FZD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77944
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5C0-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.20996
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.913322
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J9-A52C-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETV3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61466
SRF_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39937
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.448
Lung adenocarcinoma_LUAD_TCGA-J2-A4AD-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA3-24758297-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
G-401 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.701
TUNAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25377
POLR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7009
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A3Z1-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF660	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34856
SP1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Tapetum lucidum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.148
prdm9	GeneRIF Biological Term Annotations	1.0	null
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2528
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83865
OPTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47038
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2561
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11983
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18225
KMBC2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.92107
periaqueductal gray substance, ventral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.8417
LS513	DepMap CRISPR Gene Dependency	1.0	2.6503
TDRD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40874
ZNF155	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07716
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A49A-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100364_TCx_possible Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.09693
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.20533
CCK-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0588
SCML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61818
SLR24	CCLE Cell Line Gene Expression Profiles	-1.0	-1.7659
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.11
CHKA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74909
VZ in postamygdaloid region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14464
MGRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45355
EPPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7226
MCF7	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.52287
Adrenal cortical adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
GMIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88218
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OV90	CCLE Cell Line Gene CNV Profiles	1.0	1.38932
8305C	CCLE Cell Line Gene Expression Profiles	-1.0	-2.17477
IFT172	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78022
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6218-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LSM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3587
TMEM214	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8733
SARNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59848
Low tan response	GWAS Catalog SNP-Phenotype Associations 2025	1.0	10.0
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2BC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25279
dorsal subdivision of VLC	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06821
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-331-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.140752
MRPL45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95001
GSE213588_10_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC5358377-pnas.1615015114.sd02.xlsx-Sheet1-genes_with_VDR_peaks_with_and_without_D3_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
CEP41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.75812
GABPA_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease Susceptibility	HuGE Navigator Gene-Phenotype Associations	1.0	null
MOGGUVW	DepMap CRISPR Gene Dependency	1.0	4.59268
lateral nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.903857
MPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9112
protein methyltransferase activity	GO Molecular Function Annotations 2015	1.0	null
hsa-miR-3922-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.55207
single-organism metabolic process	GO Biological Process Annotations 2015	1.0	null
protein binding	GO Molecular Function Annotations 2015	1.0	null
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.926521
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.2981
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-784-ENSG00000225614_ZNF469	Rummagene Transcription Factor Associations 2026	1.0	null
PMC3643591-supp_gkt178_nar-00084-n-2013-File008.pdf-5-TSC22D1_TSC22D1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11749115-loae020_suppl_Supplementary_Table_S2.xlsx-CHOP-high-gene_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
PRDM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32539
MAF-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
18451145-TableS1	GeneSigDB Published Gene Signatures	1.0	null
hippocampus (hippocampal formation)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.35955
UBE2E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80705
UBE2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63733
SELENOF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24268
EIF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37399
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37941
ZNF565	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59642
LBR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56337
MECOM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28401
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
LHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29919
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12985
ZNF676	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38427
posterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06146
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3I3-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE-150 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.625
D283MED	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3236
GSE213588_10_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.5052
MZ in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.938339
PDK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36015
Enteric muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.903
TRAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50119
PPFIA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77391
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Smad4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.316
PMC7857731-elife-63093-supp1.xlsx-DEG_MITF-X6vsEV-SkMEL28-Unnamed_2_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-378	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
CPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99141
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXA5	JASPAR Predicted Transcription Factor Targets	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A556-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.926839
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.201
Brain Lower Grade Glioma_LGG_TCGA-CS-6186-01A-12R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TDRKH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97979
H4C11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85171
histone H3 methyltransferase activity	GO Molecular Function Annotations 2023	1.0	null
inner CP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.79376
RKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MIER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92521
15489324-TableS2	GeneSigDB Published Gene Signatures	1.0	null
Disease Progression	HuGE Navigator Gene-Phenotype Associations	1.0	null
CORO1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75024
TBX2-35687133-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SG in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23562
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29L-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CLDN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67134
Gonocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.007
LLPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64776
abnormality of the skin	GWASdb SNP-Phenotype Associations	1.0	0.421493
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29584
KYSE220	DepMap CRISPR Gene Dependency	1.0	4.8519
CA46	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29372
ERBB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2685
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.097
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.4785
SNU503	CCLE Cell Line Gene CNV Profiles	1.0	1.41602
RUNX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29435
NCI-H630	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100462_PCx_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.43482
PBX1	ChEA Transcription Factor Targets	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5K4-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXP1_01_210	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.64677
AAR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26333
NR2F1	JASPAR Predicted Transcription Factor Targets	1.0	null
chromosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3313-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0019
DLX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34453
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.832714
VAMP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54571
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
temporal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1232
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE213588_8_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RNASEH2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11713
EZH2	ENCODE Transcription Factor Targets	1.0	null
GABPA	ENCODE Transcription Factor Targets	1.0	null
KYAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96098
ZNF804B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01525
POP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18524
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.1601
HAP-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.51
HUH-6-CLONE5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TDRD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96176
HES6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4422
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
WHSC1	ENCODE Transcription Factor Targets	1.0	null
chromatin organization	GO Biological Process Annotations 2015	1.0	null
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.1805
n-methyltransferase activity	GO Molecular Function Annotations 2015	1.0	null
RENBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74642
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.2816
molecular layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03219
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.153593
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.715
ME1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58243
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11938024-ADMA-37-2413413-s001.xlsx-Table_S1a_DE_Genes_analysis-Table_S1a_Differentailly_expressed_genes_Control_vs_NPs_treated_THP1_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1	ENCODE Transcription Factor Targets	1.0	null
CEP104	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13199
integumentary system disease	GWASdb SNP-Disease Associations	1.0	0.702427
496100605_TCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.04287
FAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45107
TRMT13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24779
TMEM54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7054
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
USP9X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50642
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.08
PCYT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17615
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4864
CNPY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2273
hsa-miR-3166	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
CXADR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76287
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.83741
REST_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
epidermal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.269174
Brain Lower Grade Glioma_LGG_TCGA-FG-7637-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07529
RUNX3	ENCODE Transcription Factor Targets	1.0	null
cochlea	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.746689
FICD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52566
PRDX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35655
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_InDel-F5-Thygro-r__CIC-1n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
VLDLR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44011
RNF34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37375
LS411N	Achilles Cell Line Gene Essentiality Profiles	1.0	2.06634
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.934138
SIDT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25938
KLHDC7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2759
G6PC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32868
TGBC24TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SEMA6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17637
NPTX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85465
NCI-H1155	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39937
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02488
hsa-miR-378c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
histone H3-K4 trimethylation	GO Biological Process Annotations 2023	1.0	null
Musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.859
UBE4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22593
GLI4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67314
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UXT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36213
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054349
Skin carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.716
heart disease	GWASdb SNP-Disease Associations	1.0	0.167767
SAMD4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59913
Krueppel-associated box	InterPro Predicted Protein Domain Annotations	1.0	null
peptidyl-lysine methylation	GO Biological Process Annotations 2015	1.0	null
CCNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93669
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NUDT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79688
SPCS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26936
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.939813
BIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42502
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
blood vessel	GTEx Tissue Gene Expression Profiles	-1.0	-0.949249
LN319	Achilles Cell Line Gene Essentiality Profiles	-1.0	-3.52873
SG in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11713
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CDK5RAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78478
SCO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2496
PKIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45742
intracellular non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
CREB1	ENCODE Transcription Factor Targets	1.0	null
MMGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75102
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K029AX	CCLE Cell Line Gene Expression Profiles	1.0	2.54806
HIPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77327
SLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60062
HINT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80654
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15743
Prostate adenocarcinoma_PRAD_TCGA-G9-6354-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GA-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.70333
PTBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.8022
AGL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9536
NMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.70284
496100592_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0203
histone H3K36 methyltransferase activity	GO Molecular Function Annotations 2023	1.0	null
SALL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82052
SUMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46197
skin disease	GWASdb SNP-Disease Associations	1.0	2.34889
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.943687
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.85981
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
496100520_HIP_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.38816
SP1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer II of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.861234
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.0339
ELP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13294
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
GSE123943_4_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.48231
PRPSAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29884
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.898588
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.188263
Pectoral fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.712
SLC22A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99357
PAK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13253
OE19	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE233548_2_v_0_plscr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CMK86	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69824
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
KIF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09943
Perturb_7505_OE_ADARB1/ILF3_SRP195616	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.94403
PGPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6622
hsa-miR-759	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.8839
SOX2	ChEA Transcription Factor Targets	1.0	null
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
medial preoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.011
NAMALWA	CCLE Cell Line Gene Expression Profiles	-1.0	-2.28514
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
F36P	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.65093
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB157	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46059
Adrenocortical carcinoma_ACC_TCGA-PA-A5YG-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF385B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6281
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.948185
GSE111247_2_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IM-95	COSMIC Cell Line Gene Mutation Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23242
NCIH82	DepMap CRISPR Gene Dependency	1.0	4.962
GNG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76613
CTCF_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SREBF1	JASPAR Predicted Transcription Factor Targets	1.0	null
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ALPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.75942
APOBEC3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3924
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18183
SLC1A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3349
stratum oriens of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.832176
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202825_2_v_1_ano1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hypoglossal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11933
CBX3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inner ear vestibulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.12084
NCI-H1436	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EBF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ING4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66328
KDELR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21423
ST486	CCLE Cell Line Gene CNV Profiles	1.0	1.90795
ZBTB20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88073
CCDC61	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90336
SUGP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81759
SGF29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3686
496100384_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.69768
CTCF_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LYRM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.95925
congestive heart failure	GWASdb SNP-Disease Associations	1.0	0.525223
hsa-miR-3690	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Krueppel-associated box-related	InterPro Predicted Protein Domain Annotations	1.0	null
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF275	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89632
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
C1orf54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93747
TMEM200C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25735
NDUFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0536
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
Cell type cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.018
small intestine	GTEx Tissue Gene Expression Profiles	1.0	0.934669
BEND4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47878
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.9513
CTSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03232
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.62896
TBC1D15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52284
macromolecular complex subunit organization	GO Biological Process Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A8D0-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15227
RICTOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52878
TGOLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.59612
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRF_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.9376
RUBCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17434
PH-797804_SK-MEL-2	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0117276
RABL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74282
MLL1/2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.956
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RNF123	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.485
ZNF154	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65156
PBX3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.866987
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5683-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.78566
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GRM	CCLE Cell Line Gene Expression Profiles	-1.0	-2.26428
PEA1	DepMap CRISPR Gene Dependency	1.0	4.45342
MRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38754
Prostate adenocarcinoma_PRAD_TCGA-G9-6347-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-6560-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-NJ-A55R-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYM1	DepMap CRISPR Gene Dependency	1.0	2.54277
VSX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32345
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.20533
IQGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53631
PCNX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41109
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular non-membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
GATD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03159
regulation of nucleic acid-templated transcription	GO Biological Process Annotations 2015	1.0	null
organic cyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
GBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55051
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
HOXD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39613
CLK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69113
MLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53728
kidney	GTEx Tissue Gene Expression Profiles	1.0	1.90541
FOXP1	ChEA Transcription Factor Targets	1.0	null
FBXO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4544
PMC9753996-jci-132-160767-s182.xlsx-EBF1_associated-A1BG_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
Small cell osteogenic sarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.49
PMC11705763-mmc8.pdf-16-ZNF679_ZNF679	Rummagene Transcription Factor Associations 2026	1.0	null
DYNC2I2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05314
TRIM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03299
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.5382
RTKN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02338
HCC2218	Achilles Cell Line Gene Essentiality Profiles	1.0	1.30705
TMEM161A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81045
stomach	HPA Tissue Protein Expression Profiles	1.0	1.90051
DDAH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17365
red nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.938258
NCIH510	CCLE Cell Line Gene CNV Profiles	-1.0	-2.13693
H4K91ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
regulation of rna metabolic process	GO Biological Process Annotations 2015	1.0	null
generalized abnormality of skin	GWASdb SNP-Phenotype Associations	1.0	0.603617
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.979369
CHST12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60992
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RABL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25272
H2BC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30955
ALYREF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30908
YY1	ENCODE Transcription Factor Targets	1.0	null
KARPAS-422 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.578
RBBP5	ENCODE Transcription Factor Targets	1.0	null
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9975
C11orf54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53885
DEAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09483
SNU601	CCLE Cell Line Gene Expression Profiles	-1.0	-2.33664
CYP26A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13508
PSMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70029
APP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63123
mouse	GeneRIF Biological Term Annotations	1.0	null
SOX2-21211035-LN229-GBM	ChEA Transcription Factor Targets 2022	1.0	null
Squamous cell carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.018
SMAGP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78798
GRHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.238
SNUC5	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62131
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
eye disease	GWASdb SNP-Disease Associations	1.0	0.356657
SP2	ENCODE Transcription Factor Targets	1.0	null
GSE154936_3_v_1_remdesivir_human	RummaGEO Drug Perturbation Signatures	1.0	null
TBX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64093
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-541	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
OAW42	CCLE Cell Line Gene Expression Profiles	1.0	1.41373
solitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.85914
RNA Polymerase II Transcription	Reactome Pathways 2024	1.0	null
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12108
TAPBPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50104
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RHEB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06381
MPZL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12236
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of skin adnexa	GWASdb SNP-Phenotype Associations	1.0	0.827983
MAP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6255
C21orf91	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.399
abnormality of hair pigmentation	GWASdb SNP-Phenotype Associations	1.0	1.96614
CTCF_fibroblast of the aortic adventitia_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4700-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OUMS27	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51946
POU1F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74068
PPP1R16B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00698
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.857588
UACC62	CCLE Cell Line Gene Expression Profiles	1.0	1.4587
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-Kasumi-1-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_Kasumi-1_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
SRF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
recombination hotspot binding	GO Molecular Function Annotations 2023	1.0	null
RHOH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19432
Lung squamous cell carcinoma_LUSC_TCGA-37-A5EL-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32422
VPS51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11802
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
regulation of reciprocal meiotic recombination	GO Biological Process Annotations 2023	1.0	null
layer III of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.65924
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.908222
HCC827GR5	DepMap CRISPR Gene Dependency	1.0	4.23657
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12916
BBC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0502
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39937
ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.557263
orbital frontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.67366
RBM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13269
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5573-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hypnozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.539
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PARP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69213
FANCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32228
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18584
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC9084694-RMB2-21-e12464-s005.xlsx-GV_MI_MII_GV-up-GeneName_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
RPMI7951	DepMap CRISPR Gene Dependency	1.0	2.50254
TFIP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81218
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.67483
RAB39B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86868
NMRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09183
SNX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43547
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of skin pigmentation	GWASdb SNP-Phenotype Associations	1.0	1.96614
parahippocampal gyrus, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.980524
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_MCF-7_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYSE-520	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.83684
SNU423	DepMap CRISPR Gene Dependency	1.0	4.81711
AURKAIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83564
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7409
hippocampus (hippocampal formation)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.867725
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69504
IZ in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22361
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease	GWASdb SNP-Disease Associations	1.0	0.096387
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SO-01B-31R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4665-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE213588_10_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ATP5MC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86947
NECTIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01388
HNRNPCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63707
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.93026
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.5952
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
OE33	Achilles Cell Line Gene Essentiality Profiles	1.0	1.31477
medial mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.41067
GATA1-19941826-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
CDC34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39605
ZNF575	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29915
STK16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46622
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A6W2-06A-22R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VEZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.59672
PHF20L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40485
E2F1	ChEA Transcription Factor Targets	1.0	null
inferior rostral gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.870589
SEC14L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06658
TPSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15142
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ATP2B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55269
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19117
A-CA-04-2009(H1N1)_0Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.83771
NGRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59907
GSE213588_10_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TEAD4	ENCODE Transcription Factor Targets	1.0	null
biological regulation	GO Biological Process Annotations 2015	1.0	null
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08153
PMC11385078-jciinsight-9-172336-s272.xlsx-1DEseq2_Report_AA_BL_vs_EA_BL-Unnamed_1_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.57503
hsa-miR-335	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.859
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.53605
vestibular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.70886
496100369_PCx_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.05128
HOXD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61483
CTCF_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
N4BP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08191
HDAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52744
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null