association	dataset	threshold value	standardized value
BRD-K10058823	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34437
CRCGN009_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.32057
CRCGN015_MCF10A_48H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1755
BB-79-AG41_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.254327
PMC12179407-MCO2-6-e70261-s004.xlsx-down_TET3-KO_PQ_vs_Cas9_PQ-Unnamed_10_TET3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K53401077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0474
PMC3371315-NIHMS350140-supplement-8.xls-MCF7-T47D-SK-453_Down_MCF7-T47D-Supplementary_Table_1_ER-positive_FOXA1_signature_Genes_decreased_only_in_MCF7_and_T47D_cells_with_knockdown_of_FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K88625883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2045
BB-86-BE19_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.349449
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Combined-MYB_Combined_sgRNA_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE226249_2_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
FE-82-WB22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.714229
BRD-K50946180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15691
CRCGN016_MCF10A.TP53.M_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.67267
GSE168401_1_v_3_harmine_human	RummaGEO Drug Perturbation Signatures	1.0	null
HDAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72147
BRD-K07551625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80202
POLRMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06828
BRD-K55606442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01376
BRD-K69347147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18759
SP5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.6549
Intrinsic component of mitochondrial inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.178
YD-49-HM53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.07247
GSE120413,GSE120447_0_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GOLGA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35938
BRD-K40560569	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7189
BRD-K40733000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91265
BRD-K64763786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39158
RB-55-KL42_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.253184
GSE229978_4_v_1_morphine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12634441-41375_2025_2771_MOESM8_ESM.xlsx-ATACseq-Table_S3_Bulk_ATAC-seq_GATA2_vs_control_Only_p-adj_0_05_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K44994529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79574
GSE217776,GSE217829_1_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BC-40-TU13_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.335767
PRRC2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07184
Penile cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.039
Papillary thyroid cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.625
AB-09-YX02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.367234
BRD-K83697352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55542
GSE151090_2_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	1.0	null
WE-48-PP43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.324584
Colon - Transverse	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.03318
GSE186647,GSE217287_1_v_3_hnrnpc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Stat5a::Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.5791
BRD-K04544693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.25243
GSE131649_6_v_7_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
DA-07-LL18_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.266675
BRD-K17536501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.24044
BRD-K04498687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06094
BRD-K16496880	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.05631
BRD-K21588993	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.13858
BRD-K00411149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40664
GSE120413,GSE120447_4_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE154577_7_v_10_plagl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1624
GSE143212_1_v_2_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.704372
GSE216538_1_v_3_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE57397,GSE57399_1_v_0_fbxw7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CE-69-HJ13_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.353635
ZNF251	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04168
496100343_TCx_possible Alzheimer's disease_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.49961
GSE143462_0_v_1_omipalisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE86507,GSE86509_3_v_9_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DC-51-WE27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.384727
CHRNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13126
GSE157555,GSE157556_0_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE235066_4_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100460_TCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.28635
BRD-K88467167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66116
CRCGN008_HEPG2_24H:H04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.37025
KA-81-AG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.43302
BRD-K90762344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21727
BRD-K16330310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59853
GSE75976_3_v_6_abl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AC-84-QG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.404101
PMC6078853-molce-41-7-695-suppl2.xlsx-Sheet1-Table_S1_Genes_exhibiting_two-fold_changes_in_expression_between_WT_and_CTCF_KO_otocyst_with_FDR_less_than_0_05_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
Cytosolic large ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.961
GSE86507,GSE86509_7_v_10_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
INIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08302
GSE242290_3_v_2_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K59747214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49241
FA-88-II68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.33551
BRD-K63493628	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45252
HDX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14089
BRD-K32718856	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63122
BRD-K87433679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49251
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	76.25
NOC2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32339
GSE213715_0_v_1_iqgap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
OB-06-WW76_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.310464
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SLF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2663
GSE213588_10_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF135	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.9177
TRMT112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10699
GSE128730_4_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE154577_6_v_10_plagl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193993_4_v_3_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.32615
GSE129293_0_v_1_chd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BC-56-CP81_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.319078
GSE76425_0_v_5_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE172494_3_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
MICOS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.96
GSE112761,GSE112767_1_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE157555,GSE157556_3_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K16633334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26861
BRD-K77417197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1381
RBM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.07235
GA-28-SS67_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201953
HD-18-YL30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.212515
CRCGN011_HEPG2_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0189
BRD-K01627964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84511
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.5909
Muscle - Skeletal	GTEx Tissue Gene Expression Profiles 2023	1.0	1.64859
PMC9218776-ADVS-9-2104640-s002.xlsx-SIM_-_Nurr1-Unnamed_1_SIM2	Rummagene Transcription Factor Associations 2026	1.0	null
Thymus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SRSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20837
ADISSP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09258
BRD-K16479784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33465
BRD-K84815485	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29452
GSE140441_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K69659917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11607
BRD-K00793226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09586
BRD-K49042040	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15924
BRD-K16331797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.47326
GSE113817_0_v_1_bach1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_downregulated_genes-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE219103,GSE219104_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
DVL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00089
Hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K20733942	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71332
BRD-K43000271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.2471
BRD-K64535513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.30972
GSE48812_11_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GC-40-VJ01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.235914
GSE231799_2_v_4_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K23701005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84855
BRD-K62472719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20458
GSE148066,GSE157787_0_v_1_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TIM22 mitochondrial import inner membrane insertion complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.596
BRD-K23286105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10465
FB-66-UU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202698
BRD-K06619604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25055
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K86677819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0839
BRD-K44803159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7488
BRD-K58382884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11308
Penis carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.356
GSE221327_4_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A_48H:H22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.75161
CRCGN011_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3247
BRD-K03309398	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95197
BRD-K89094496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10216
CRCGN012_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14201
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Differentially_Expressed_Genes_DEGs_of_OE-HIF1A_vs_OE-GAL4_Veh_in_Bulk_RNA-seq_Data_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
PSMD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57071
BRD-K07384081	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25112
GSE235701,GSE261434_0_v_1_enasidenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:G12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.60198
BRD-K03542527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5637
BHLHE40	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0105
BRD-K72439355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10133
DA-20-VR86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.209334
GSE95688_7_v_5_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RPL38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39621
BRD-K35108166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2893
AB-33-EM56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.466242
EA-17-BY69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204923
CRCGN009_HEPG2_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1692
BRD-K86454955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32233
BRD-K72807299	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86927
BRD-K39491844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33303
GSE120413,GSE120447_0_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K40061713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01527
GSE144838_1_v_8_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE218060_2_v_6_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6995218-12864_2020_6525_MOESM3_ESM.xlsx-D2FAST48h_vs_D2REFED4h_641_AR-D-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE63857_3_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-MECP2-toNode_MECP2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K02517738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51385
496100327_PCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.47989
GSE171572_0_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE126127_0_v_1_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K45222498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49751
BRD-K03489727	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20081
PMC3607232-mmc1.xls-RS411_SEM_common_AF4_MLLN_K79Me-MLL_AF4_H3K79me3_SEM_n_2490_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
Mitochondrial intermembrane space	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.301
CLINDAMYCIN-PO4	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1728
GSE148066,GSE157787_9_v_1_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Mitochondrial creatine kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.563
BRD-K27058632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67749
BRD-K43359161	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22214
GSE180641_0_v_1_zfp503_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-9_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN008_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.91405
GSE147210_3_v_5_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE240645_3_v_2_u90926_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LPCAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3994
JD-62-HR05_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.30235
CRCGN017_MCF10A.WT.HP_24H:M23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0641
PF-59-CY33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.414537
GSE147210_2_v_5_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K57833824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40099
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCall_EPC1-PHF1_FLAG_K562-SYMBOL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.27094
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-10_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K50127933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.418
BRD-K45519638	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31184
BRD-K36120694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28324
BRD-K53110645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08166
Creatine kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.514
mdamb415	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.994
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-1_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE174498,GSE174500_5_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
KF-18-RY71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.418244
TONSL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35378
AA-86-YY62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.228051
BRD-K11880555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09685
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.497561
BD-49-MD69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.393513
GSE131649_6_v_5_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ATP1A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75735
EHF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92793
BRD-K63401627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61298
CIAO2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12523
Organelle envelope lumen	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GSE140651,GSE140653_2_v_1_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE221327_5_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213588_8_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE190322,GSE190324_3_v_4_rbm4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135030_11_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
WASH complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.501
ZNF76	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5888
CRCGN015_MCF10A.TP53.M_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.27505
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.4074
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-D1-D3_643_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-MBNL1_KD_HFE-145-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
POMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2788
BRD-K13844473	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94346
BRD-K09166899	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50019
BRD-K74537725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14655
GSE204832_0_v_1_imiquimod_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF-_SURVIVAL-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
BA-15-VE07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.247165
HME1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.925
HOXA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04811
GSE226285_3_v_1_nr0b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RPS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61577
CRCGN008_HEPG2_24H:J17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1528
CRCGN015_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.86672
BRD-K63086103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67299
PMC6879454-Data_Sheet_1.xlsx-AA_disease-Unnamed_4_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE189683_1_v_0_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6404
TA-34-CK62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201486
GSE43041,GSE43044_0_v_1_ldb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148066,GSE157787_11_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1813
BRD-A33596659	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26599
BRD-K96238295	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59071
CRCGN016_MCF10A.TP53.M_24H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.33948
EE-03-SG02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.673829
PMC3607232-mmc3.xlsx-a_RUNX1_SEM_MLLN_AF4C_H3K79Me-x_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE57871_5_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EC-62-OE64_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.238111
PMC5578490-pgen.1006879.s017.xlsx-Top_ETV1_downregulated_genes-Gene_Symbol_ETV1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE160083,GSE160084_2_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K04366109	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07369
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.5595
VMAC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0257
GSE130690,GSE130692_1_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DHX40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08169
BRD-K58534227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05744
BD-84-ZR31_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.256142
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.72179
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K57096799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56135
BRD-K17416171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26464
BB-20-UU03_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.235458
BRD-K29614616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74368
ZR-75-30 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.771
WBP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36262
GSE153871_1_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4815041-NIHMS715090-supplement-Supplementary_Table_10.xlsx-CCF_DP_clustering-Hugo_Symbol_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN009_HEPG2_24H:J17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.10342
BRD-K73556828	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43536
PMC8160578-JCB_202009147_TableS4.xlsx-E2F1_targets-Genes_n_1867_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
FC-20-EQ58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.685912
BRD-K10416099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.30881
BRD-K09376136	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12127
TMA16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3243
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_17_KD_HEK293-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Transcriptional Regulation by TP53	Reactome Pathways 2024	1.0	null
CRCGN015_MCF10A.WT.HP_24H:L20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09544
Mitochondrial envelope	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.1955
GSE201309_5_v_0_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE190316,GSE190324_1_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE223008_0_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.07535
TAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03725
BRD-K27616520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10757
FEZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.3208
HTT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10409
BRD-A88461048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26686
PD-70-VS77_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.253318
GSE213588_8_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
QA-50-YO37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207297
GSE90019,GSE90020_5_v_2_phf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UF-27-HS98_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.319043
PMC9564215-pnas.2203480119.sd02.xlsx-OVCAR-5_SCD_KD_cultured_in_low-hgnc_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K68162101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01268
GSE231799_3_v_4_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MDK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58819
GSE120413,GSE120447_3_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE242290_1_v_2_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K20072174	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00724
JD-81-YX02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.297918
CRCGN015_MCF10A_48H:E10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.044
PMC6400843-Table_5.xls-C_FOXM1_Correlated_genes-Symbol_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE118794_0_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KLF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.3074
CREBRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61525
GSE147210_3_v_4_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.51378
BRD-K91039552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61447
BRD-K71566411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52204
CABLES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03193
BRD-A18825024	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13926
GSE190316,GSE190324_1_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A09988375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24134
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_KD_K562-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_ENSEMBL_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
TCF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6081
GSE205729,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:G12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.42505
BRD-A78982410	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09665
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.463189
BRD-K87419143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12881
BRD-K68270916	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33061
GSE171572_3_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A59391763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46475
NUBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17603
WC-09-GD62_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.248317
GSE186810,GSE186813_2_v_5_furin_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GA-87-BR97_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.481682
BRD-K49992772	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.42643
GSE110178_2_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K07667635	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76389
BRD-K32686643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01103
BRD-K88128293	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69222
GSE131588,GSE131690_1_v_0_setd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE88819_6_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IA-76-ZU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.297831
GSE112761,GSE112767_4_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_10_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE148692,GSE148695_5_v_4_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
STAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03805
GSE229973_4_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
KA-75-LP02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.224108
Integral component of mitochondrial membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.88
BRD-K27600134	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00109
DCAF4L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21367
HC-92-HE59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.281972
BRD-K13679727	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57841
GSE118765_1_v_5_rreb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142210_11_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE242290_1_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FD-86-NE74_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.275152
BRD-K73434853	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49531
phospholipid transfer activity	GO Molecular Function Annotations 2025	1.0	null
GSE159937_2_v_0_tfcp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE140937,GSE140938_0_v_2_slfn11_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K85500722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82113
BRD-K75730049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29623
GSE112761,GSE112767_1_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE48812_4_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K20053005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0516
CRCGN015_MCF10A_48H:H23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23285
OB-06-WW76_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.388731
BRD-A41208012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16416
EMILIN complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.036
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1476
PMC5263239-mmc2.xls-SEM_wt_MLL-Gene_name_1614_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K34456337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39767
GSE131649_4_v_7_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K32319151	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18187
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2739
SNAPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33194
ATRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36747
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3295
TP53 Regulates Transcription of Cell Death Genes	Reactome Pathways 2024	1.0	null
PNPLA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95034
GSE234637_2_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE174498,GSE174500_3_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
TICRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06981
BRD-K52620056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.15255
carboplatin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34386
BRD-K13206026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21233
BRD-K78816149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41155
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-Partitions_EPC1-PHF1-FLAG-Unnamed_20_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K69093885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58587
BRD-K05734090	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92069
BRD-K79995507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90488
GSE138468_3_v_6_dyrk1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE139239_1_v_5_ddr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K10847374	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50463
GSE212486,GSE212488_0_v_1_gata4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE69869_0_v_1_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
B16-F1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.538
BRD-K63277230	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41606
YE-55-YX75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.24819
BRD-K53821452	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.18321
BE-79-QU25_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.298625
BRD-K13696195	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.25134
GSE122215,GSE122217_5_v_1_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.WT.HP_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21941
B-CPAP cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.698
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Supplementary_Table_4B_DEGs_in_ATF4-def_cells_comparing_Tg_2h_to_its_DMSO_control_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K42679620	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95102
Mitochondrial intermembrane space	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
lipid transport	GO Biological Process Annotations 2025	1.0	null
Brain - Putamen (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.03689
Generic Transcription Pathway	Reactome Pathways 2024	1.0	null
GSE48812_7_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K60777422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0414
GSE123861_1_v_0_sin3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K89476396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14142
BRD-K67809808	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31135
GSE214248_0_v_1_cxcl8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216540_0_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:K18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.76335
ZB-16-BR73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.234264
BRD-K68379391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94715
GSE159678_6_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Golgi trans cisterna	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.69
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.50012
BRD-K71817857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.52174
GSE95077_5_v_3_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02296
BRD-K10989535	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95955
GSE244710_1_v_0_srsf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NOP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.96374
NPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33028
PRDM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03781
496100352_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.28936
ABT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10469
CRCGN016_MCF10A.WT.HP_24H:F20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.10462
BRD-K79148949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02136
LRRC58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1811
Chromosome 18p deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.43
Npas2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.2022
KLF15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	85.0217
HINFP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0788
BRD-K04036799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74364
BRD-K88746179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49399
GSE157049,GSE157051_6_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
DHX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5117
GSE174498,GSE174500_3_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE128333_4_v_1_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K39267096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69361
CCDC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09745
KXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19303
Creb3l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.1892
GSE174701_5_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K63997411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52456
AA-68-OJ16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.24521
Mlxip	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.0
GSE125782_0_v_2_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE121246_1_v_0_stat5b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN010_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.82853
GSE142210_3_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K43680691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84488
BF-94-CQ58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.313179
GSE166920_6_v_4_adalimumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_3H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22439
BRD-A68427178	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43429
MLXIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41687
CRCGN015_HEPG2_48H:E18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11914
LSM12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7785
BRD-K98189856	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17368
BC-25-VR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.743876
GSE146072_0_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.67427
Immune system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K58284640	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14681
BRD-K68383485	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42506
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-Embryo-Hatchling_1272_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A68175400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.44414
CRCGN015_MCF10A.TP53.M_24H:F21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1892
ZNF574	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.3873
BRD-K76900919	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79746
BRD-K00938872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64808
PMC8191339-mmc1.xlsx-Table_S3_DE_genes-LPS_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4687
BRD-K92012390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46617
BRD-K20028052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74126
GSE100863,GSE100864_3_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GC-04-UF36_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.207651
GSE235066_7_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC5640240-ppat.1006668.s013.xlsx-MAX_ChIP_shEP400-1-Unnamed_6_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K87034416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39792
GSE199255,GSE199356_4_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ME-31-RM40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227084
BRD-K98601267	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42383
PB-09-OE00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.4376
BRD-K09227140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9169
BRD-K04706894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63602
FF-28-ES17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.395629
GSE88819_11_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE217776,GSE217829_2_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8979
GSE226316_3_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ACOT13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00266
BRD-K47631316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13556
BRD-K77884956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2877
GSE56235_1_v_0_prdm11_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Mitochondrial prohibitin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.339
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E18-D3_2440_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6995218-12864_2020_6525_MOESM3_ESM.xlsx-D2FAST48h_vs_D3REFED24h_1198_AR-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-combined_portrait-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.28454
BRD-K25773863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31994
CRCGN016_MCF10A.TP53.M_24H:P21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.45861
GSE226285_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K87669186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61067
INA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.963
GSE86507,GSE86509_3_v_5_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE131649_2_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE148252_5_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Arnt	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.95
BRD-K07336866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12112
BRD-K82112239	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86072
GSE213588_10_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K68301602	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14219
BRD-K45888106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33967
GSE102132_2_v_1_irf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K17185909	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15732
STK36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.03188
BRD-K18865369	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40852
GSE242290_3_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC3607232-mmc1.xls-MLLN_prom_RS411-MLL_body_RS411_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
Mesenchymal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.561
GSE213588_10_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A.WT.HP_24H:P17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04758
BHLHE23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03372
KCNK17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03405
GSE157555,GSE157556_0_v_6_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE48812_7_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
200d	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.532
CRCGN010_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.6331
INTS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73994
MAPKAPK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15177
CRCGN016_MCF10A.TP53.M_24H:F11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19896
BUD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00705
BRD-K64073423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51114
BRD-K07383982	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50534
ZNF770	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.2006
BRD-K40228963	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01642
BD-96-HO33_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.468947
GSE183327,GSE183328_1_v_0_ddit3_human	RummaGEO Gene Perturbation Signatures	1.0	null
DC-51-WE27_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.322896
BRD-A83672804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55109
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.2657
PMC4909989-ncomms11840-s2.xlsx-down-regulate-TEAD4-FL_YAP_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
CSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06536
BRD-K60507129	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89746
BRD-K75207324	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69347
BRD-K52062350	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11292
PMC7532671-thnov10p10957s2.xlsx-Table_S6A-Table_S6A_Differentially_expressed_genes_DEGs_in_DDX5_KD_versus_WT_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE110178_5_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K43384508	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52319
PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_SYMBOL_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6995218-12864_2020_6525_MOESM3_ESM.xlsx-D2FED48h_vs_D2FAST48h_968_AR-DE-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K09117810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22275
GSE120612_4_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cpa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.605
GSE57871_1_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K18519876	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.13582
GSE152441,GSE152442_6_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K06743908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67213
BRD-K09206831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21658
BRD-K87790666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84137
BRD-A48913311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0025
BRD-K35304243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03387
BRD-K94845132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0302
CEP164	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01626
CRCGN017_MCF10A.TP53.M_24H:N20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.121
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.1371
CRCGN017_MCF10A.TP53.M_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.02194
GSE169697,GSE169725_0_v_5_prrx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K62659610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5046
BRD-K45185240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0687
phosphatidic acid transfer activity	GO Molecular Function Annotations 2025	1.0	null
KRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35982
EOLA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45659
GSE201239_3_v_2_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A_48H:D08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.55187
pi1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.629
GSE142210_3_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE174498,GSE174500_5_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE57875_1_v_0_hnrnpl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE155836,GSE155839_3_v_2_alvocidib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8494348-pone.0257161.s002.xlsx-only_OXT_NOT_ext-OXT_ext-Gene_Name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K77609086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18268
Thorax	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE213588_8_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC3610249-1471-2164-14-184-S4.xls-miR-331-3p_targets-NR2E3_NR2E3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A23340824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33853
BRD-K72549552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38205
GSE249404_0_v_1_oxytocin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Brain - Nucleus accumbens (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.00718
BRD-K70870890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38679
RPS18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07349
GB-57-XV52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.738013
AA-58-FJ71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.31417
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8098
BRD-K18599462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47279
AD-86-ES28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.482819
GSE186065_0_v_1_sirt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K15997423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06569
GSE120370_4_v_3_thrombin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
drofenine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80825
GSE122067_2_v_1_mtch2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.72796
CRCGN016_MCF10A.TP53.M_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.64085
Tongue cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.879
organophosphate ester transport	GO Biological Process Annotations 2025	1.0	null
lomofungin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87792
BRD-K89364982	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58962
GPATCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06652
BRD-K08241590	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17583
FD-91-OK66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.2059
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_17_KD_HEK293-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HSPA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93624
butyrylcholine-cl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29057
GSE214514_1_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE166920_6_v_2_adalimumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE244710_3_v_2_srsf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2546
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-Partitions_EPC1-PHF1-FLAG-Unnamed_19_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
cls1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.949
BRD-K59856141	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53154
PMC10794847-mmc5.xlsx-PIAS1_KD_down-Table_S4_Differentially_expressed_genes_with_PIAS1_knockdown_in_the_progenitors_state_Related_to_Figure_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE168401_1_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K38998073	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10254
GA-28-SS67_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.268634
GSE211963_0_v_3_cd200_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NME6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24297
BRD-K30019337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92905
CRCGN015_HEPG2_48H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.64294
C19orf25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03142
SB-94-ZA83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.221615
mdamb157	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.623
GSE202434,GSE202438_2_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8141032-NIHMS1694738-supplement-Supplementary_Table_1.xls-MYC_BAF155_BRG1-Unnamed_14_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K12955049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06809
GSE57871_6_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KLF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	79.4766
BRD-K67137502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3317
TCF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3932
PA-75-VL17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207774
BRD-K30661365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37897
GSE210476_11_v_4_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ERF::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2564
GSE142210_9_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K79678951	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92521
RNF113A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01347
BRD-K39237487	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.522
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3006
GSE122425_1_v_0_nsun2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBED4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	98.7727
BRD-K05123945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10095
BRD-K03015524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07575
PMC6928094-395_2019_765_MOESM7_ESM.xls-DEGs_AR7_vs_Pre-patterned-List_of_differentially_expressed_genes_in_AR7_vs_Pre-patterned_cells_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
naltriben-mesylate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74108
MLX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2633
MCM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51506
JC-06-ED36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.423107
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227221
BRD-K77203880	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40447
EIF5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21474
BRD-K16357911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11064
BRD-K77041516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07937
GSE240027,GSE240030_5_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HSFX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06675
BRD-K43468685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80451
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.00347
PMC6400843-Table_5.xls-C_FOXM1_Correlated_genes-Ensembl_ID_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.06959
GSE140651,GSE140653_2_v_6_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE140936,GSE140938_0_v_1_slfn11_human	RummaGEO Gene Perturbation Signatures	1.0	null
A549_Celecoxib_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0115225
PMC8200296-LSA-2020-00928_TableS2.xlsx-table_s2_DEGs_log2foldchange_0-Table_S2_List_of_DEGs_induced_by_YY1_knockdown_YY1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE223008_4_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE151612_4_v_3_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_downregulated_genes-Unnamed_6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
DF-00-BU08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.542994
DD-74-PJ26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.51422
DMAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0347
BRD-K67531128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89657
BRD-K16976282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47897
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K38907993	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49963
GSE195568_3_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PD-70-VS77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202623
IMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41516
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.512475
PMC4467436-oncotarget-06-6267-s002.xlsx-140527_cd44Cutoff_txt-PAX6-M_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
PB-09-OE00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.36093
BRD-K75360899	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06588
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.23985
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Nearest_Ensembl_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K94191869	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29478
BRD-A82394575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51721
BRD-K20185935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09587
PMC9218776-ADVS-9-2104640-s002.xlsx-SIM_-_Nurr1-Nurr1_modulation_mediates_neuroprotective_effects_of_statins_SIM2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K86349956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23737
RPL19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07444
HOXB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25757
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E18-D1_1591_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K87316858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33852
BRD-K64704925	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5541
Artery - Tibial	GTEx Tissue Gene Expression Profiles 2023	1.0	2.99319
GSE120612_6_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
phospholipid transport	GO Biological Process Annotations 2025	1.0	null
GSE131887_1_v_0_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K43341506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09507
RFNG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37717
IFT57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5757
BRD-K94775036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40684
CA-75-HA22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.679807
IA-76-ZU47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.208214
BRD-K18573205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05948
BRD-K45348630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74935
BRD-K82019575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61709
PMC5798892-41421_2017_3_MOESM7_ESM.xlsx-TM_KO_vs_WT-Supplementary_Table_S2-2_Up-_and_downregulated_genes_in_ATF6_cells_relative_to_ATF6_cells_in_the_presence_of_TM_early_passage_ATF6	Rummagene Transcription Factor Associations 2026	1.0	null
ATP11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14576
ZBTB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1132
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
EB-67-WB79_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.249624
GSE148514_0_v_1_rreb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12824706-BLOOD_BLD-2025-028441-mmc3.xlsx-Fig4B_genes_inc_expr_NRF1-gene_name_NRF1	Rummagene Transcription Factor Associations 2026	1.0	null
chr18_12495950_GAC_G_b38	GTEx eQTL 2025	1.0	1.35175
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE157555,GSE157556_4_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K42799692	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12056
GSE213588_10_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
OB-17-DQ74_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.232791
PMC5848610-supp_gr.228809.117_Supplemental_Table_S4.xlsx-Table_S4D-Supplemental_Table_S4D_List_of_differentially_expressed_genes_upon_siZFX_with_promoters_bound_by_ZFX_in_C42B_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE148692,GSE148695_5_v_6_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K14269958	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12726
BRD-K64182862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47545
Esophagus - Mucosa	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.64874
BRD-K41331757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03179
GA-28-SS67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.226061
BRD-K19579217	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73104
PMC8283158-mmc2.xlsx-TCF4_ChIP-symbol_TCF4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K41202439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17116
BRD-K09454191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7756
BRD-K39705203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.09098
SMAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4838
GA-47-MH68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.670703
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
S0-EE-Y7IR_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.344813
C1QTNF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14807
RPAIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53795
BRD-K48582996	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3
GSE129241_1_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE235066_4_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RNA Polymerase II Transcription	Reactome Pathways 2024	1.0	null
CRCGN017_MCF10A.WT.HP_24H:A14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1499
GSE215155_0_v_1_golph3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45832
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6852
BRD-K97410356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06188
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-6_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K12397820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64457
BRD-A60487173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29697
GSE186471_1_v_2_carnosol_human	RummaGEO Drug Perturbation Signatures	1.0	null
mitochondrial intermembrane space	GO Cellular Component Annotations 2025	1.0	null
SNCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01836
PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Shee2-The_differentially_expressed_genes_between_the_BARX2_high_and_BARX2_low_group_of_LIHC_patients_BARX2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-8_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K79324911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08697
GD-66-XE49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.205272
SMARCE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00424
BRD-K58932103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58527
JE-72-KV75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.312423
GSE122215,GSE122217_0_v_1_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.323365
BRD-K05122615	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09011
PMC10534007-Table_2.xlsx-S5_unique_up_MSC_B-721_elements_included_exclusively_in_BFTC905_MSC_up_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9169777-pnas.2120787119.sd07.xlsx-Sheet1-Dataset_S7_Significantly_differentially_expressed_genes_between_G2_and_GATA3_WT_T-ALL_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE120370_0_v_3_thrombin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K14193598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90746
DCTN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72191
DDX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36743
BE-36-XE09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.209348
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0058
GSE174418,GSE174421_2_v_3_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PD-70-VS77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.511125
HA-22-CY42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.331352
chr18_12438520_C_G_b38	GTEx eQTL 2025	1.0	1.82285
BRD-K27356753	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23045
GSE131649_6_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K52520268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.33744
GSE176008_7_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE235066_4_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K19814171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23261
BRD-K42480393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46309
BRD-K20895937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.18505
BRD-K05635176	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02643
BRD-K10232513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93878
CRCGN012_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06601
BRD-K45062933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11392
GSE192870_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE220520_6_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE173810_0_v_1_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE184133,GSE184137_1_v_5_esrrb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nrf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	54.752
Apoptosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.787
BRD-K67022703	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03263
BRD-K84310612	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07001
HD-51-KD29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.254993
FF-86-NH56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.444029
LHX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36282
BRD-K59507567	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17536
Arntl	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.4938
BRD-K99522349	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84003
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCall_EPC1-PHF1_FLAG_K562-ENSEMBL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K58735963	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04328
BRD-K15434241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14927
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
QA-07-KC40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.241375
CRCGN017_MCF10A.TP53.M_24H:L05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.02448
GSE210580_0_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE72895,GSE72896_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE220520_1_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BE-85-CH49_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227552
LAYN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31284
BRD-K15928912	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92161
GSE189941_1_v_2_kdm4c_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE112761,GSE112767_2_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE129186,GSE129223_0_v_1_aicda_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-2_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K54864501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23022
GSE122215,GSE122217_5_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE57871_1_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE151612_0_v_3_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K64147309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40816
RABL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1584
GSE232836_2_v_6_morphine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Pituitary	GTEx Tissue Gene Expression Profiles 2023	1.0	1.49073
EEF1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	9.0061
CF-87-AS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.284208
BRD-K44492160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32536
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.6627
KA-81-AG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.460809
GSE231799_2_v_1_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K14671528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32509
USP9X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17372
TNPO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0938
NR4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18093
PMC11682006-13105_2024_1045_MOESM1_ESM.pdf-92-PRR12_PRR12	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E16_vs_D1_1084_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K86463534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56871
PMC6935105-40170_2019_206_MOESM9_ESM.xlsx-HIF1_down_VENN-1175_elements_included_exclusively_in_HIF1_down_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8519939-41525_2021_248_MOESM5_ESM.xlsx-MYC_UP_V1_UP-Gene_name_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE242290_1_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE226249_2_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K54025526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21335
MTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12416
BRD-K72145393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71265
BRD-K66963616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33821
ZB-16-BR73_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.205405
PMC4909989-ncomms11840-s2.xlsx-down-regulate-TEAD4-S_YAP_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K92725027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26893
BRD-K28952606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01334
GSE142210_9_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K18594025	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01437
BRD-K85668200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3733
CRCGN014_HEPG2_24H:B06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.91496
496100611_FWM_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.52055
496100315_TCx_no dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.31845
BRD-A81260764	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23941
GGTLC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13737
Brain - Cerebellar Hemisphere	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.869745
GSE112860_5_v_8_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE159446,GSE159449_1_v_0_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K67862892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09539
PMC5105166-ncomms13331-s11.xlsx-Sheet1-Supplementary_Data_10_Overlap_of_upregulated_genes_in_MEF2D-rearranged_cases_with_public_ChIPseq_RNAseq_data_MEF2D	Rummagene Transcription Factor Associations 2026	1.0	null
GSE213588_9_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.2845
TSHZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47195
BRD-K32269272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15921
RBBP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02007
GSE200687,GSE200688_1_v_0_sox15_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE117045_1_v_0_amphetamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FARSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17614
GSE221327_5_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE226285_3_v_1_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE184399_0_v_2_cnot1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE206400_3_v_0_nusinersen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PD-70-VS77_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.649878
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E20-D3_1775_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K20810649	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38367
BRD-K41643612	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07721
GSE158969_1_v_2_trastuzumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Gene_Name_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
ATP6V1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0654
GSE143212_0_v_3_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Organelle envelope lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.231
GSE159678_4_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K90697694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06325
BRD-A70099008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30731
CRCGN015_MCF10A.TP53.M_24H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2265
AD-31-GO06_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.361017
FE-64-KC49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.71172
BRD-K61034310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50324
BRD-K74107343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02268
RNF146	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14612
Mitochondrial crista junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.985
GSE192870_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:B20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0469
CB-49-OG36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.272166
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.59186
496100532_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.75087
BRD-K70158474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19993
Organelle envelope	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GTEx Colon 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	17.098
BRD-K92701606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01923
RELB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30777
GSE157036,GSE166411_3_v_1_halofuginone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.227138
PMC7441006-41388_2020_1389_MOESM2_ESM.xlsx-Supplementary_Table_1-Prostate-Specific_MYC_Overexpression_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE99112_0_v_1_upf3b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K44426506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26671
BRD-K28545166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19422
DF-00-DK69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.355837
BRD-K94936556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71386
BRD-K56889360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25942
MDA-MB-361 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.586
BRD-K15343767	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17226
PMC10933434-44319_2024_69_MOESM1_ESM.xls-HRV16_vs_MI-Associated_Gene_Name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A17741195	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17261
BRD-A71962374	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.96609
GSE158834_7_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE145323,GSE145324_1_v_0_rfx3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8384902-mmc6.xlsx-DEG_3TF_KD_unique-GeneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K10087503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28868
GSE216757_4_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Tongue epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.977
CRCGN017_MCF10A.WT.HP_24H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.41182
BRD-A11130173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51495
BRD-K61199074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09687
BRD-K91683342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32448
GSE242290_3_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC5352183-oncotarget-08-624-s009.xlsx-Table_S20-1_indicates_that_the_gene_is_both_a_TP53-MW_and_a_TP53-MSN_gene_in_the_correponding_cancer_and_0_indicates_not_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
EE-98-PF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.58504
Zfp961	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.7616
GSE241701_1_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4269325-NIHMS634665-supplement-supp_table4.xls-H3K27me3_TRIM37_KD-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE225735_0_v_4_aldosterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEx Colon 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	1.0	4.53627
TF-04-RX73_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.233583
BRD-A17902629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10414
UF-27-HS98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.655126
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5E-Down_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K13069055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04663
GSE113005_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100318_PCx_probable Alzheimer's disease_TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.14157
ND-15-RC31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.623573
BRD-K03546460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44981
496100608_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05696
BRD-K59535072	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42997
GSE149366_1_v_0_sulconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K94088690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70841
AFF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11298
CRCGN015_MCF10A.TP53.M_24H:B17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.44065
BA-84-WN26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.695634
BRD-A04231641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36941
GSE186810,GSE186813_7_v_5_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Arnt::Hif1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.7019
PMC8322331-41598_2021_94805_MOESM3_ESM.xlsx-b_STAT3_UP_assoc_transcripts-Gene_ID_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K38853406	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53487
BRD-K09721867	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23026
GSE188458_2_v_1_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN014_HEPG2_3H:D13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01832
CRCGN017_MCF10A.WT.HP_24H:I09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.64765
KCNS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89929
BRD-K02979518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84657
Lymphoid tissue	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN017_MCF10A.WT.HP_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8694
BRD-K75037209	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52366
GSE196343_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE244710_3_v_0_srsf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:E20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5017
GSE159728,GSE159730_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.11391
ACTRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60579
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-7_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
LD-39-FL02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210894
GSE248858_6_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8D-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_WT_3T3_ONLY_1626_GENES_MNT	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K27584103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6692
PMC12549544-mmc2.xlsx-AA_D1_VS_D7-Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K22437400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.27374
CRCGN017_MCF10A.TP53.M_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.31769
Listeriosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.033
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5211
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4469
Minor Salivary Gland	GTEx Tissue Gene Expression Profiles 2023	1.0	0.887147
GSE233112_2_v_0_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Papillary thyroid cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.598
GSE71385_1_v_0_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7548
GSE202310_1_v_0_ube3d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K09376957	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7297
BRD-K95213130	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4395
ERMES complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.547
POLR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14782
BRD-K70851631	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20785
BRD-K02675272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12654
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4644
GSE213588_10_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE216540_1_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K23430114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50816
BRD-K61139423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00231
CETN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88319
Gene expression (Transcription)	Reactome Pathways 2024	1.0	null
PMC8481886-Table_2.xlsx-A_subsets-common_MSC_AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K32476586	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34326
PMC4531812-13058_2015_618_MOESM11_ESM.xlsx-Metabric_Sparse_KM_976-TFAP2B_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K25305749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71689
vacuole-mitochondrion membrane contact site	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.951
PMC8519939-41525_2021_248_MOESM5_ESM.xlsx-MYC_UP_V1_UP-Ensemble_gene_ID_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE229344_2_v_0_cyb5r3_human	RummaGEO Gene Perturbation Signatures	1.0	null
DA-81-VY50_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.373541
CRCGN009_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.3325
GSE122215,GSE122217_0_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE139948_3_v_6_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
JE-04-LS32_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.230672
MAX::MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8571
BRD-K20171002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01782
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Unnamed_1_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10933434-44319_2024_69_MOESM1_ESM.xls-HRV16_vs_MI-Ensembl_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
z85	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.141
BRD-K50114736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54289
BRD-K90040724	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74978
GSE242290_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE86507,GSE86509_3_v_2_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-5_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K16862492	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02328
QF-71-QI30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.304157
Integral component of mitochondrial inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.881
Trunk	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K73149920	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46724
496100412_FWM_possible Alzheimer's disease_TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.76793
BRD-K93176491	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3207
BRD-K08107521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96232
GSE86507,GSE86509_0_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K45394633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7961
BHLHA15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53303
BRD-K30201819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25585
BRD-K05699155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82127
PMC12634441-41375_2025_2771_MOESM7_ESM.xlsx-RNAseq-Table_S2_Bulk_RNA-seq_GATA2_vs_control_Only_p-adj_0_05_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K58498516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00238
GSE57871_5_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SA-32-CC58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.362476
GTEx AdiposeTissue 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	1.0	6.09022
BRD-K17854062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68511
GSE202434,GSE202438_9_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE131649_4_v_5_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE131649_4_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOXC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22405
PDLIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48552
BRD-K25917968	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28979
Gli1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.0772
ZBTB14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.5082
GSE151412_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE152441,GSE152442_7_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A27422067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86413
BRD-A77164655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1424
BRD-K73443280	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08817
GSE100863,GSE100864_2_v_1_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.09721
GSE159893_2_v_1_genistein_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE231720,GSE231724_3_v_0_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3694
Intrinsic component of mitochondrial membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.177
BRD-K98880643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40695
CRCGN013_HEPG2_24H:M10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.17579
GSE186471_1_v_0_carnosol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Skin - Sun Exposed (Lower leg)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.808458
GSE161771_0_v_1_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K05185748	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16404
GSE174701_5_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KB-92-MK13_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.32273
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_KD_K562-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-N87 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.024
BRD-K35520972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01689
GSE166920_6_v_3_adalimumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HSPA1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1266
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE86507,GSE86509_4_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169590_0_v_1_rptor_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_6_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE155031_5_v_1_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7291745-12967_2020_2407_MOESM2_ESM.xlsx-Table_S1D_CCF_pairs-locus_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE57871_11_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K03070790	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30622
BRD-K95068765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10825
GSE139239_2_v_6_ddr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OF-05-CB18_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.50434
CRCGN017_MCF10A.TP53.M_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.35265
BRD-K14139166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.22639
SF-67-CJ22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.407
SP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	94.5674
BRD-K56336567	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.25536
TOR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56767
GSE109140_0_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100497_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12215
BRD-K25608271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18898
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release	Reactome Pathways 2024	1.0	null
GSE217378_2_v_0_lin28b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A67521865	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34511
GSE127790_13_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEx Ovary 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	5.3231
GSE229231_0_v_1_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6589
CRCGN015_MCF10A.TP53.M_24H:O22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3529
BRD-K92806245	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50066
PMC8141032-NIHMS1694738-supplement-Supplementary_Table_1.xls-MYC_BAF155_BRG1-Unnamed_15_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN011_HEPG2_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6241
BRD-K83877780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20677
GSE216540_10_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K47597660	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4265
MPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0066
BRD-K79299080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06031
BRD-K65529782	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34576
GSE140651,GSE140653_2_v_7_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10785552-13059_2023_3149_MOESM7_ESM.xlsx-RNAseq_HOXA9_rescue-Table_S6_The_DEGs_in_in_RBM5_KO_cells_with_HOXA9_overexpression_relative_to_RBM5_KO_control_HOXA9	Rummagene Transcription Factor Associations 2026	1.0	null
NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.3829
BRD-K71177762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66733
BRD-K11979048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11732
PMC9404532-NIHMS1788564-supplement-Supplementary_Tables_1-8.xlsx-Supp_Table_6-MYC_UP_V1_UP_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
H2BW1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18705
ZNF561	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06398
BRD-K73802986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18447
GSE48812_0_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE143782_3_v_4_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE186810,GSE186813_7_v_5_furin_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K19534880	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.53662
CRCGN009_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.55148
GSE157894_2_v_0_cystine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:H10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00497
GAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56387
BRD-K09395335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47115
FF-86-NH56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.378849
DF-93-BT88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.256255
CRCGN014_HEPG2_24H:A14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.22683
BRD-K20183527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12758
BRD-K77046858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12006
RPL13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84872
BRD-K70264850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18582
VAV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48054
PMC8384902-mmc5.xlsx-H128_ASCL1_ChIP-Symbol_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE149901_2_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE130081,GSE130082_0_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TBC1D24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09673
BRD-K72071403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03624
BRD-K48056188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06896
BRD-K96417480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50923
FA-80-DR66_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.241146
Cervix - Ectocervix	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.888317
GSE174498,GSE174500_2_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K07035171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03056
PMC6995218-12864_2020_6525_MOESM3_ESM.xlsx-D2FAST48h_vs_D4REFED48h_750_AR--Gene_Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
QE-79-XO29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.306632
MED9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96694
BRD-K92372829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81453
BRD-K45058172	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66387
PMC11392782-Table1.xlsx-Table_S4-Supplementary_Table_4_MR_and_colocalization_results_of_mitochondrial-related_gene_expression_on_T2DM_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.18085
HCN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47002
CRCGN015_MCF10A.WT.HP_24H:K18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.55079
BRD-K13196166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70799
BRD-K20831543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29249
VA-06-DB75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.536012
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E16_vs_D3_1784_AR-DEGS-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K71419092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96086
GSE179880_1_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE86507,GSE86509_0_v_8_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE112860_9_v_8_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE224969,GSE224971_3_v_1_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE159893_2_v_0_genistein_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE186810,GSE186813_2_v_5_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
JA-23-QE71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.283245
PMC3607232-mmc1.xls-MLLN_prom_RS411-MLL_prom_RS411_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
CC-68-YZ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.407792
BRD-K15714771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77441
AF-99-HA02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.432081
DD-36-YH76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.546212
DC-23-UM36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.494099
GSE151612_4_v_7_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K19501975	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33782
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4054
SP9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	83.7498
FB-66-UU47_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.203672
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.6841
BRD-K02921955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83641
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-3_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K52354895	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64591
PRPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4103
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.39761
BT-483 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.747
GSE171572_5_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
FA-88-II68_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.33823
CRCGN015_MCF10A_48H:O07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00236
CRCGN015_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06135
BRD-K80044183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12574
EA-18-FP00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.251347
PMC4531812-13058_2015_618_MOESM11_ESM.xlsx-TCGA_Sparse_KM-TFAP2B_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
GCLC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08503
Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.7373
NE-00-JZ19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.268495
GSE122067_2_v_0_mtch2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE174383_6_v_5_ly6d_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K98343273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3373
BRD-K76885311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29925
CRCGN015_MCF10A.TP53.M_24H:L09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.82295
AC-55-XA97_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.23821
BRD-K15373812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88573
YD-49-HM53_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.326751
DDIT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44104
GSE221327_4_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213588_9_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-MBNL1_KD_HFE-145-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K89199943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07774
ABCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02717
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-4_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE195743_1_v_4_lhx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K78907463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07405
PMC5836443-12864_2018_4568_MOESM5_ESM.xlsx-Fatty_Acid_Metab_66_AR-DE_genes-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A80081229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22989
Mitochondrial proton-transporting ATP synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.568
CRCGN013_HEPG2_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.113
WASHC2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60736
GET3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02689
BRD-K66802550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37874
BRD-K15269548	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19071
BRD-K95014616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15673
GSE166920_6_v_1_adalimumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RBM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36586
GJD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40324
GSE152734,GSE152735_2_v_0_pbrm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PD-05-HV36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.208413
BRD-K04667232	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45109
GSE86507,GSE86509_3_v_10_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null