association	dataset	threshold value	standardized value
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GRHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.945
septal nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.864381
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46405
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.07819
MYOG	ENCODE Transcription Factor Targets	1.0	null
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.975692
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5406
Kidney Chromophobe_KICH_TCGA-KM-8476-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferior olive, dorsal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23847
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-CA-04-2009(H1N1)_12Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.12608
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14282
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3426-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM139	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0277
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00875
primary auditory cortex (core)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.60597
59M	DepMap CRISPR Gene Dependency	1.0	2.24107
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.1558
IOMMLEE	CCLE Cell Line Gene Expression Profiles	1.0	1.89764
magnocellular (medial) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.855334
ntera2	HPA Cell Line Gene Expression Profiles	1.0	0.825086
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00875
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A553-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00673
Liver hepatocellular carcinoma_LIHC_TCGA-5C-A9VH-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LU134A	DepMap CRISPR Gene Dependency	1.0	2.04424
RPP25L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5441
GSE143662_3_v_1_dcp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12178829-mmc4.xlsx-Sheet_4-MEG3-KD_Up-GeneName_AR	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.48911
WHAMM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51827
INSM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.0833
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.999417
Macular degeneration	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.852
AN3 CA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.869829
TNFRSF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28016
IER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59951
frontal pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.2051
NFKBIZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64551
SLC35D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22101
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.8575
posteroventral (inferior) parietal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.866974
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4K20me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.59347
IV, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.13544
WDR59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13998
UNC5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.02985
IPMK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30766
AOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1961
BHY	CCLE Cell Line Gene Expression Profiles	-1.0	-1.80221
H3K36me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NQO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29608
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-XS-A8TJ-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TFAP2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	165.4
PRPF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29125
PF382	DepMap CRISPR Gene Dependency	1.0	3.67685
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.39453
ILF3_02_148	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60607
GSE229698_1_v_2_traf7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.48117
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.61245
SU-DHL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46405
REP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55643
CLDND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27787
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE242290_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.62735
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.312337
PMC6379364-41598_2018_37489_MOESM2_ESM.xlsx-Sheet2_DESeq_MSC_vs_fibroblast-Unnamed_1_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
RPS20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51368
ATG14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98114
posteroventral (inferior) parietal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20206
NFE2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01562
Brain Lower Grade Glioma_LGG_TCGA-DU-6407-02B-11R-A36H-07,TCGA-DU-6407-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92357
CAL-12T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-3.81507
SNAPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43787
PIP5K1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78778
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.954779
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149124,GSE149128_2_v_1_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SJSA-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.935735
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
AIMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03686
CEBPB-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K36me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-A5EN-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE242290_1_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K36me3_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SH3BGRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54596
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZIC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73269
Tripartite attachment complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.397
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.34474
RHPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2831
ACTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59989
GSE133213_11_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RHOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92389
HACD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78026
RCHACV	DepMap CRISPR Gene Dependency	1.0	4.27511
TUBA1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40287
Lung adenocarcinoma_LUAD_TCGA-50-5051-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-UE-A6QU-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34579
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ESPNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42107
FECH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81011
FOXA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05467
Sarcoma_SARC_TCGA-DX-A6YZ-01A-12R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.27465
SMAD2/3-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TNFSF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58907
OVCAR-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.87817
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.9469
H3K36me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE217526_0_v_1_parthenolide_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary auditory cortex (core)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.04766
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.901644
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11278
SNU81	CCLE Cell Line Gene Expression Profiles	1.0	2.14176
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.863632
ACTR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22194
Primary T cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.931494
GSE199543,GSE239447_0_v_4_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
subthalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07062
CAOV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.60755
ORC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59256
lateral reticular nucleus (principal part)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2629
Methyl accepting chemotaxis protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.329
RAP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69801
FOXF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50464
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4718-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE139948_3_v_2_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-FC-A6HD-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-53-A4EZ-01A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A5A4-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.877472
hek293	HPA Cell Line Gene Expression Profiles	1.0	1.16731
Kuhnt-Junius degeneration	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.693
Prostate adenocarcinoma_PRAD_TCGA-2A-A8VX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ENDOU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82452
testis_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.11425
COL8A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47628
MZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.956109
GSE183041_1_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
COV644	CCLE Cell Line Gene Expression Profiles	-1.0	-1.65138
PMC12500934-41408_2025_1358_MOESM3_ESM.xlsx-Table_S6-DEGs_p_0_05_between_surviving_or_deceased_DLBCL_patients_that_received_R-CHOP_therapy_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.5049
hippocampus (hippocampal formation)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.67542
medial mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.20021
laterodorsal part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.41912
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.994003
Brain Lower Grade Glioma_LGG_TCGA-DB-5274-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37903
Brain Lower Grade Glioma_LGG_TCGA-RY-A83Y-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EP-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1195	CCLE Cell Line Gene CNV Profiles	-1.0	-2.25187
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IO-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SACS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94904
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.970834
TATDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.065
CLPP_KO_GDS4791_107_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ECSCR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59844
MCAS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.877715
diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.361019
primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.28257
PMC9530161-41419_2022_5296_MOESM2_ESM.xlsx-Tab6_KDM5C-KD-up_genes-Table_6_Up_regulated_genes_in_KDM5C-KD_KDM5C-KD1_Control_overlap_KDM5C-KD2_Control_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Diazinon	CTD Gene-Chemical Interactions	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-3005-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10455
posterior (caudal) superior temporal cortex (area 22c)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.91823
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4811-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0999
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WH-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A4AU-01A-32R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TPST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56041
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.17997
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4847-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-F2-A44G-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HTR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9434
STRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89266
FAAP100	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82428
inner CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33396
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4845-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
subparafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06421
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1741
IGSF9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97917
ventrolateral prefrontal cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.881035
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ASMTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12508
GSE133763_0_v_2_chd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
skin	HPA Tissue Gene Expression Profiles	1.0	1.45764
Lung squamous cell carcinoma_LUSC_TCGA-90-A4ED-01A-31R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDC25A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3536
MBD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21591
SPAG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05491
TP73	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3259
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.908669
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.908669
GSE101239_5_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TMEM134	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30439
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.49182
POLR2A_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AU565	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42954
TSSK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.03578
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.44384
SYDE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02221
MM1S	CCLE Cell Line Gene CNV Profiles	1.0	1.54797
CSNK2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33746
MARCKS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27275
BRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38033
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A562-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9160255-41467_2022_30710_MOESM4_ESM.xlsx-AR_specific_regulated_genes-ENSEMBL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NFE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11192
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07568
CHL1DM	DepMap CRISPR Gene Dependency	1.0	3.56932
RBM48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36071
GSE166783_3_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60936
AP5Z1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85994
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TIA1_KO_GSE54418_261_mouse_midbrain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NCIH1915	CCLE Cell Line Gene CNV Profiles	1.0	1.39535
SG in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03983
HCA1	DepMap CRISPR Gene Dependency	1.0	2.01833
POC1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51569
HO-1-U-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CLPP_KO_GSE40207_388_mouse_testis	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
inferior temporal gyrus, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.982754
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.972282
PMC7378211-41598_2020_69015_MOESM3_ESM.xlsx-EWS-WT1_rep1_testp-7_annotatedp-Gene_Name_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
SW 48	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.35896
ICE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01891
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.864827
Lung adenocarcinoma_LUAD_TCGA-62-A471-01A-12R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02031
LOVO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FBXW9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5136
HLA-DRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62541
ZNF451	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57265
EFO-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.484
STON2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89636
EIF4G3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22007
Clear cell adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.128
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01482
EEIG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34861
UBALD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17344
Lung adenocarcinoma_LUAD_TCGA-95-A4VP-01A-21R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE-510	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CCDC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23741
abnormality of carbohydrate metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.222983
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GALNT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53125
SMAD4-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ME1	CCLE Cell Line Gene Expression Profiles	1.0	1.88978
cetuximab_homo sapiens_gpl570_gse21483	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CLDN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26915
RPEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97241
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.116
POLR3E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84324
SP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01724
cuneate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.62917
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.878441
SCAMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96284
Perturb_11455_KD_GPRC5C_ERP135375	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.36851
PER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38375
NEURL1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27956
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.2185
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.883066
PITHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7161
ATP1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57919
Bladder Urothelial Carcinoma_BLCA_TCGA-S5-A6DX-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53423
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.865736
GMPPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74294
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.52562
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JM-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRPL49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16078
PPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57542
GRHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0179
H3K36me3_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TTC30A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27043
POLR2AphosphoS2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216540_10_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Ensembl_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
DD-36-YH76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.338295
Prostate adenocarcinoma_PRAD_TCGA-XQ-A8TA-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Leaf disc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.896
Lung adenocarcinoma_LUAD_TCGA-MN-A4N1-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H376	DepMap CRISPR Gene Dependency	1.0	2.21159
ENO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5281
subgenual (subcallosal) division of MFC (area 25)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.861866
MFN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96321
CCNE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04909
H3K36me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CLDN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07275
ARSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90967
CTSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03232
RNF112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23301
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CDC42BPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81017
GSE86507,GSE86509_0_v_8_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10214295-mmc4.xlsx-B_-_Beta_Cell_ZBTB16_targets-Gene_Name_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
Retinal degeneration	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.852
CF-87-AS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204599
H3K36me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LASV_FML29_24hr_24069471_GSE41300	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.90954
MMAC-SF	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PTPN23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45798
H3K36me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IKZF1_01_138	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60975
C11orf96	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17346
COMMD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37789
Lung adenocarcinoma_LUAD_TCGA-55-7728-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
caudal division of IPC (area 39)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1689
H3K36me3_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMD8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.00441
MED16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89232
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14282
Kidney Chromophobe_KICH_TCGA-KO-8414-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-QH-A65R-01A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FD-91-OK66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.21311
CDKN2AIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40793
HS 940.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.26814
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.921086
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13602
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
PNPLA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9134
COL7A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50099
BCP1	CCLE Cell Line Gene Expression Profiles	1.0	1.51451
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.96821
H3K36me3_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IMPDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42905
PMC9160255-41467_2022_30710_MOESM4_ESM.xlsx-AR_specific_regulated_genes-SYMBOL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HLA-A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22705
abnormality of the endocrine system	GWASdb SNP-Phenotype Associations	1.0	0.099198
endometrium_8b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.38561
SMOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61324
FOXP1-21924763-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ATXN7L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36515
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.38172
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2912
ZNF671	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42833
H3K36me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW837	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55855
NHLF	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.36326
Lung adenocarcinoma_LUAD_TCGA-97-8552-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-68-7757-01B-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.886
TARBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67707
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GAL3ST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38584
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33377
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.3235
PMC7378211-41598_2020_69015_MOESM3_ESM.xlsx-EWS-WT1_rep1_testp-7_annotatedp-ID_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
RIOK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75027
GSE133213_6_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KC-A7F5-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-A5DJ-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K36me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100605_TCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.48057
H3K36me3_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ABI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82867
YEATS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78897
SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.879435
UBE2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3684
CNOT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82637
SG231	DepMap CRISPR Gene Dependency	1.0	2.07678
ZNF470	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46902
DDX19A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81524
anterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.0647
GSE88819_1_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GOLIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5978
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A708-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF701	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	106.101
FLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.74121
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.185553
H3K36me3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAVIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84269
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.24861
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.965778
VPS13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53843
CHCHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77288
Lung squamous cell carcinoma_LUSC_TCGA-O2-A52V-01A-31R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCCOHT1	DepMap CRISPR Gene Dependency	1.0	3.66106
CTPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22318
RCOR1	ENCODE Transcription Factor Targets	1.0	null
NCIH1944	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49946
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A47N-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCDC136	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53744
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.28928
TBKBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15091
LIN28B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22623
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.87947
GSE153064,GSE153065_1_v_0_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97618
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q7-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAB29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51244
ALDOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56273
EEF1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-7.82121
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07034
GSE247764_0_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IB-33-TE51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210381
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07568
JHUEM3	CCLE Cell Line Gene Expression Profiles	-1.0	-1.74441
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM106C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00661
ZNF135	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89157
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14209
TFAP2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	178.753
Perturb_17278_KO_Upf2_SRP038144	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
LC-12-VN85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.206031
EFE184	CCLE Cell Line Gene CNV Profiles	1.0	1.76301
BMF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94798
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.841198
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A40Y-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M3-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.0305
ECE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62606
MAPK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63748
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.863977
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.916405
Lung squamous cell carcinoma_LUSC_TCGA-77-8150-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.942885
JVM2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6864
ZNF580	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.4706
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14282
NCIH1650	CCLE Cell Line Gene CNV Profiles	-1.0	-2.20636
RPL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43754
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A495-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CORL279	CCLE Cell Line Gene CNV Profiles	1.0	1.95918
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.92468
PPP1R16B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00698
RNF38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90731
III, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.883825
NCI-H1155	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SYT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60114
HDAC6	ENCODE Transcription Factor Targets	1.0	null
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.39627
ventral posterior inferior nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08392
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.338
PMC10625120-ADVS-10-2304638-s002.xlsx-Table_S6-Table_S5_The_RNA-seq_of_KLF5_in_OVCA420_cells_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
stratum radiatum of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.886526
RNF114	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11493
outer CP in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0632
H3K36me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.850487
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.922115
Lung adenocarcinoma_LUAD_TCGA-97-A4M0-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RXRA::VDR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6
TAF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07957
H4K20me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ARHGEF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13106
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
ZNF675	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60519
HDAC2	ENCODE Transcription Factor Targets	1.0	null
A-431	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46763
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5475
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZF-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ASH3	DepMap CRISPR Gene Dependency	1.0	3.09063
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GT-01A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE228181_4_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.841226
MXD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40061
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SU-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.14531
subcuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.56101
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.10307
NXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56923
DOTC2-4510	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100631_PCx_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.34955
SIRT6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ANKRD23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27075
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A217-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE235066_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Ebf2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.1647
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0387
SLC5A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72026
GSE242290_1_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SRI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41522
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-05A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.991413
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34509
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47W-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAB3IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03779
posterior (caudal) superior temporal cortex (area 22c)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22642
NB10	DepMap CRISPR Gene Dependency	1.0	2.51706
PMC8898985-NIHMS1734801-supplement-1734801_Supp_table.xlsx-5B-Hypothalamic_Vglut2_Cnr1_Ninl_Rfx5_Zfp346_Neuron_ZNF346	Rummagene Transcription Factor Associations 2026	1.0	null
inner SZ in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12464
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7398-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158834_12_v_9_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.83065
DOHH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53176
H3K9me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.852
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CO-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SHROOM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86217
cingulate gyrus, parietal part, left, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.898008
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.6088
MAPACHS77	DepMap CRISPR Gene Dependency	1.0	2.26528
C5orf22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88778
MIS18BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08338
FOXP1-21924763-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE57871_11_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.957513
COLO684	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69376
ZCCHC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16834
H4K20me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HADHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2757
PALM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15885
inner SZ in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10817
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15285
inferior rostral gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14931
NEK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20933
AGPAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.39445
LMNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5744
H3K36me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE122101,GSE122103_3_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210682_2_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09525
Prostate adenocarcinoma_PRAD_TCGA-HC-A6HX-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28574
Cell pole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.808
CNNM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34357
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.842292
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4992-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPP1R3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62631
H3K36me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_13684_OE_JMJD3_SRP151752	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.897
TBX2-33478486-IMR90-HUMAN-LUNG	ChEA Transcription Factor Targets 2022	1.0	null
TRIM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26298
HL-60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.05177
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3445-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.853485
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7344
EVSAT	CCLE Cell Line Gene Expression Profiles	1.0	1.79209
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.67982
MLXIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42841
striatum_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33246
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.2105
GSE88819_1_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.911154
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.993
GGNBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39014
amygdaloid complex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17178
OVMIU	DepMap CRISPR Gene Dependency	1.0	2.42119
SLC25A34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84461
ABI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34139
CACNA2D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36247
PRELID3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03937
NUGC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.3882
Mesothelioma_MESO_TCGA-SC-A6LN-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE235066_4_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L7-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE248769_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.38294
ZNF816	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	113.913
RB1_KD_GSE50532_591_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HAPLN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41833
Pancreas	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	2.7595
diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.324331
testis_7b	HPA Tissue Sample Gene Expression Profiles	1.0	1.46047
ZNF143	ENCODE Transcription Factor Targets	1.0	null
H3K36me3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2I	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45068
PAQR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03542
SYNGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28487
THOC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73556
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.76242
orbital frontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01167
AML193	DepMap CRISPR Gene Dependency	1.0	2.86841
FBXO46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40767
PGAM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82824
PPM1M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41457
ALCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.662
Lung adenocarcinoma_LUAD_TCGA-86-A4JF-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GART	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49183
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A6I3-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30247
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.8844
ZNF320	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	235.787
SNAI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.3869
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20775
RPS6KA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41856
NAV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19063
PC3	CCLE Cell Line Gene CNV Profiles	1.0	1.33702
HCT 116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.27234
DZIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87858
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease	GWASdb SNP-Disease Associations	1.0	0.025268
GSE158834_2_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A871-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.975625
H2AC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44891
CTCF-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GP5D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.77268
CSTF2T	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05404
H3K9me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23454
JMJD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27113
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
principal sensory nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3751
496100641_PCx_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.45073
KCL-22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TRIM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38454
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09725
H3K9me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
TRAPPC6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37116
EBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40956
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.33949
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.82825
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03042
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.7095
HEV_60Day_None_GSE53731	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.80121
GSE210655_3_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45W-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HARA	CCLE Cell Line Gene Expression Profiles	1.0	1.36879
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.5339
PMC8787225-Data_Sheet_1.xlsx-STable_2_DEG-Supplementary_Table_2_1150_up-_and_down-regulated_differential_expressed_genes_upon_GATA2_activation_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
FOXP1	ChEA Transcription Factor Targets	1.0	null
H3K36me3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4965
RHOXF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37079
CSNK2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12549
SLC37A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37905
Head and Neck squamous cell carcinoma_HNSC_TCGA-MZ-A5BI-01A-31R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.701
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A262-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32283
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23454
OST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42239
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.928451
NPEPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50886
ZNF581	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80177
NCIH647	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36912
GSE82110,GSE82299_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PARN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72239
NECTIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06264
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01771
PARP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25395
GSE151494_8_v_3_nrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-OE-A75W-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03921
OVOL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41461
ACO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34004
REH	DepMap CRISPR Gene Dependency	1.0	3.8853
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4969-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10824666-43018_2023_699_MOESM2_ESM.xls-Suppl_Table_S4-AM-1882_AUC_vs_Gene_Expression_PRISM_Breast_and_Ovarian_Cancer_Cell_lines_n_58_1_PRDM6	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HW-A5KJ-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LX-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR2C2AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19271
outer plexiform zone in extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12489
MV411	CCLE Cell Line Gene Expression Profiles	1.0	2.13653
SLITRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73152
FITM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.84806
OVKATE	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.032
anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.70373
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-3.23468
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58516
GSE233679_5_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RPS6KA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96038
ventrolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.77498
Brain Lower Grade Glioma_LGG_TCGA-QH-A6X4-01A-51R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE168797_2_v_0_cannabidiol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE209582_1_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE124375_13_v_0_chd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LGR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36066
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7378211-41598_2020_69015_MOESM3_ESM.xlsx-EWS-WT1_rep1_testp-7_annotatedp-Nearest_Ensembl_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.84856
TE11	DepMap CRISPR Gene Dependency	1.0	3.09225
NMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.05337
amygdaloid complex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.933413
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.67354
HOXB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28134
AB-97-BI36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.260024
Lassa Fever Virus_24hr_24069471_GSE41300	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.8849
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.79924
SENP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06297
MCF7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.89116
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.881884
POLR1F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3381
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.31141
MAST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.174
HMEL	CCLE Cell Line Gene Expression Profiles	1.0	1.67245
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.851168
SET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8673
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01709
GSE137702_2_v_1_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4553
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3I3-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PJVK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68736
primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11529
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7UE-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-MP-A4T6-01A-32R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TIGD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.17857
Lung squamous cell carcinoma_LUSC_TCGA-68-A59J-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63443
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.855445
PMC6855629-pone.0225186.s009.xlsx-Sheet1-DEGs_downregulated_in_HEK293_MEIS1_KO_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
TUBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13382
496100455_FWM_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.49175
ACTL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52061
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.66208
GSE186647,GSE217288_1_v_7_hnrnpc_human	RummaGEO Gene Perturbation Signatures	1.0	null
ENSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95037
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6HZ-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5338
GSE103068_5_v_1_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EN	CCLE Cell Line Gene CNV Profiles	1.0	2.60226
head of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.92968
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11593
KRBA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24491
FD-59-TC81_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.31653
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A5U2-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
substantia innominata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.894675
Lung adenocarcinoma_LUAD_TCGA-86-A4D0-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158834_11_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE156454_0_v_1_tamoxifen_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K36me3_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ULK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75557
PMC12178937-mmc6.xlsx-L_AKAP12_KDvsD_AKAP12_KD_deg_al-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ARTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20042
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-CA-ID_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
RKO	CCLE Cell Line Gene Expression Profiles	1.0	2.6517
RNF103	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09066
FARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87493
KALS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HOXB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02798
SETD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16358
METTL7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95019
PROCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85179
CCDC66	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03966
SESN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56921
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4873-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_16962_KD_PAX2_SRP044867	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
LRRC61	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8798
layer II of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.865959
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Periplasmic space	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.319
NCAPG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99011
GSE190316,GSE190324_1_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Genetic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.852
ECC10	CCLE Cell Line Gene CNV Profiles	1.0	1.36514
INPP5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31147
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73G-01A-22R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12518476-10067_2025_7574_MOESM8_ESM.xlsx-Sheet1-Down_regulated_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF33A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21841
PRICKLE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45007
GSE142210_2_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92201
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GZ-05A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100613_TCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.4481
GSE166783_8_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17453
PMC12775252-18_2025_5991_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_2_Up-_and_down-regulated_genes_in_TCF7L2-depleted_EVT_compared_to_control_EVT_TCF7L2	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DESI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50874
UBE2W	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9113
pineal gland	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.68901
SFXN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.78337
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TX-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF234	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20234
MVD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4907
SNAP29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05201
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.921778
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.883371
PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
hmc1	HPA Cell Line Gene Expression Profiles	1.0	1.65115
POLR2AphosphoS5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_splenic B cell_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COX7A2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90685
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A8OU-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K36me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.918199
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS-21BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.70528
HARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20263
Lung adenocarcinoma_LUAD_TCGA-50-8460-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-8_DEGs_RUNX1-OE_vs_control-Gene_Symbol_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A6J1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
u266	HPA Cell Line Gene Expression Profiles	1.0	0.892096
UGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98975
TP63	ChEA Transcription Factor Targets	1.0	null
LYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29617
Adrenocortical carcinoma_ACC_TCGA-OR-A5J5-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-8148-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-NJ-A4YQ-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF876P	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93129
temporal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.56361
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A3MF-01A-12R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AA-23-FM46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.322299
HEC50B	DepMap CRISPR Gene Dependency	1.0	3.14687
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3Y7-01A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW756	DepMap CRISPR Gene Dependency	1.0	3.98403
KLRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9212
RDX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56506
GSE169356_2_v_3_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01771
primary motor cortex (area M1, area 4)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04515
TRAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19229
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.217042
RNF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.65713
reticular nucleus of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.900887
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SRP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21263
CORL24	CCLE Cell Line Gene Expression Profiles	-1.0	-3.05238
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.922115
SUDHL4	DepMap CRISPR Gene Dependency	1.0	2.13453
GSE158834_12_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K36me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCDC177	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11927
ALLSIL	CCLE Cell Line Gene Expression Profiles	1.0	1.36469
496100658_FWM_probable Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01484
gracile nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.892495
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9246
HNRNPLL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21709
GSE231745_1_v_0_venetoclax_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GCM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.9902
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.987383
SEMA5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32533
mediodorsal nucleus of thalamus_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.00422
Lung squamous cell carcinoma_LUSC_TCGA-22-1012-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAL62	DepMap CRISPR Gene Dependency	1.0	2.16919
H3K36me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSDMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02334
CITED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57121
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07403
PCYOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.37153
HL60	CCLE Cell Line Gene Expression Profiles	1.0	1.67731
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-gene_id_x_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
OGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35072
QDPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49538
PGLS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60875
EXTL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84546
Brain Lower Grade Glioma_LGG_TCGA-P5-A737-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hESC_Derived_CD56+_Mesoderm_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.06408
SART3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14623
NPFF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91819
peripheral portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.862044
ETAA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51151
WDR37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96508
primary somatosensory cortex (area S1, areas 3,1,2)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.908511
paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.92605
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-8580-01A-31R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LIMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61418
DNAJA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83046
PPP1R2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60839
TGBC11TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12085
ChIP_RCOR3_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
HKBMM	DepMap CRISPR Gene Dependency	1.0	2.30042
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38624
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.0238
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04046
DNAJB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16232
primary auditory cortex (core)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.31328
TNIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09588
ITM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31665
CRAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52928
TMEM178A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32304
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.07447
MRPL22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46812
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12557
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10455
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IG-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POGLUT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26761
GSE158834_10_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
LATS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05902
PCI-38	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SA1-27219007-CHIP-SEQ-ERYTHROID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HTR1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1147
FAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27296
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00875
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.40863
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.5891
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-A4AQ-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
QTRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87103
esophagus_5c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.31952
GSE128730_4_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IFITM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6632
PPFIA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42905
ADH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20343
PSMB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64333
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23345
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.44044
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46763
PSMB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7255
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09312
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4833-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-QM-A5NM-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09136
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-Row_names_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
IDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55992
hippocampus (hippocampal formation)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.68736
NUP153	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7736
GSE233112_2_v_0_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E6-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8958
RBM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19595
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6948-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WC-09-GD62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.211899
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05017
KDM3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52728
SLC45A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70849
CSRNP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38312
KLM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1802
KCTD17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91449
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.56955
POLR2AphosphoS5_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1833	CCLE Cell Line Gene Expression Profiles	-1.0	-3.07524
Prostate adenocarcinoma_PRAD_TCGA-EJ-A65D-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FBH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97218
UACC-893	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.888927
CDC42EP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69695
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IM95	CCLE Cell Line Gene Expression Profiles	1.0	1.53146
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A6I3-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
spleen_3b	HPA Tissue Sample Gene Expression Profiles	1.0	0.918661
UBF1/2-26484160-CHIP-SEQ-FIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PRDM9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	160.802
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6992-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10214295-mmc4.xlsx-A_-_Human_Islets_ZBTB16_targets-Gene_Name_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52298
SLC35E4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77809
RHPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37257
Sarcoma_SARC_TCGA-DX-A8BH-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90283
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10455
Nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.852
Sarcoma_SARC_TCGA-IS-A3KA-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CLPP_KO_GDS4791_104_mouse_testis	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.24329
Silique	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.876
Spleen	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.05744
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.48947
ZNF492	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43989
TM9SF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57073
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2ND-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU738	DepMap CRISPR Gene Dependency	1.0	2.47803
IKBKE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59561
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.99618
BOLA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93282
METTL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26009
CHCHD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93005
NHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.5762
GSE218500_0_v_3_ruxolitinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74814
Sensory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.852
POLR2AphosphoS5_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endopiriform nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.901189
MRPS28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39965
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.929759
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PARP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48531
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.99087
GSE241622_1_v_0_ythdc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cholelithiasis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.779
PMC11252405-41467_2024_50426_MOESM4_ESM.xlsx-Fig_S4c-CTCF_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE95386_0_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	1.0	null
NDUFV3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78213
NEUROG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05804
CBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7551
TMEM138	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.18894
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09447
H3K36me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05664
POLR2AphosphoS2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92764
MV-4-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07449
TMEM9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28271
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.27438
Sarcoma_SARC_TCGA-X6-A7W8-01A-21R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2279	CCLE Cell Line Gene CNV Profiles	1.0	1.46464
Acute Myeloid Leukemia_LAML_TCGA-AB-2861-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE167956_1_v_0_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
RT11284	DepMap CRISPR Gene Dependency	1.0	2.84502
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30166
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AW-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NHLRC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57792
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.865966
ACSL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12254
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.45082
TCP10L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26109
Gallbladder disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.116
H3K36me3_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-3011-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRKD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3264
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.922742
PIP4K2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.555
SLC45A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89689
APOBEC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22205
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158834_11_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Age related macular degeneration	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.852
U266B1	CCLE Cell Line Gene CNV Profiles	1.0	1.77024
OCI-AML5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.917557
H3K36me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.14866
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.06378
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4776-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AMZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23319
NCI-H2795	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.98186
LAMTOR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04416
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3288
H3K36me3_CH12.LX_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KARPAS1718	DepMap CRISPR Gene Dependency	1.0	3.53076
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.19435
GSE179974_3_v_4_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SMCR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92235
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLAGL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	106.226
DEL	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38485
Perturb_8806_KD_SON_SRP279434	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.28971
CHML	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37986
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.74863
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A6C6-01A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF888	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85427
mediodorsal nucleus of thalamus_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41663
posterior (caudal) superior temporal cortex (area 22c)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.899162
Bladder Urothelial Carcinoma_BLCA_TCGA-S5-AA26-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Spindle pole body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.778
ACTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8761
SUDHL5	DepMap CRISPR Gene Dependency	1.0	2.01649
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03193
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.56553
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HL-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.20608
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.857736
OCIMY7	CCLE Cell Line Gene CNV Profiles	1.0	1.38333
EGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23146
ZEB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05939
rectum_8b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0425
Rectal Mucosa Donor 31	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.90779
PMC7403583-41598_2020_69884_MOESM2_ESM.xlsx-Sheet1-Supplementary_Table_1_Differentially_Expressed_Genes_FDR_q_0_05_in_U2932_ROCK2_KD_vs_Scrambled_shRNA_Constrols_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MAFG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74579
DUSP22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79056
fusiform gyrus, left, bank of cos	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.21251
Kidney Chromophobe_KICH_TCGA-KO-8409-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE57871_11_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-MM-A564-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.862839
amygdalostriatal transition area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07115
KATOIII	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37354
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.63602
GSE167956_4_v_0_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
smoothmuscle_8b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.61493
Lung adenocarcinoma_LUAD_TCGA-97-A4M1-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAMDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32071
medial group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.955609
POLR2AphosphoS5_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.116175
hr5	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.869
H3K36me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
HMGN3	ENCODE Transcription Factor Targets	1.0	null
subgranular zone of caudal dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.44766
NDFIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07413
SNIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47158
Lung adenocarcinoma_LUAD_TCGA-NJ-A4YP-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE57871_1_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5KX-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MOLM13	CCLE Cell Line Gene Expression Profiles	1.0	1.74622
PMC10214295-mmc4.xlsx-B_-_Beta_Cell_ZBTB16_targets-Ensembl_Gene_ID_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
CASTOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01382
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
temporal pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.961945
CBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00168
GSE154337_0_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-DX-A3UD-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DKMG	CCLE Cell Line Gene Expression Profiles	-1.0	-1.7929
TET1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31397
SARS-CoV MA15_Day4-PFU-10^5_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.71653
pancreas	HPA Tissue Protein Expression Profiles	1.0	1.1792
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.942885
ZDHHC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96565
periplasmic space	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.757707
AMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85796
KCNJ14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37215
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.61431
GP2D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.52634
ZFP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.07033
PMC10245467-mmc3.pdf-139-ZNF551_ZNF551	Rummagene Transcription Factor Associations 2026	1.0	null
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.26223
POLR2A_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fruit capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.871
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.858229
ALDH7A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01295
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47V-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PNPLA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14675
STAT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22646
Pancreatic adenocarcinoma_PAAD_TCGA-F2-A44H-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE127261_1_v_2_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
DHRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45432
JVE015	DepMap CRISPR Gene Dependency	1.0	3.25485
C6orf141	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80187
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4642-01B-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SULT2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87832
ZNF202	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47465
H3K36me3_CH12.LX_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04098
HINT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67499
ENO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47175
carbohydrate metabolism disease	GWASdb SNP-Disease Associations	1.0	0.321978
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KJ-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYO19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46564
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HI-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE90552_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ATP6V0D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23053
KLHL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70287
PPIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29342
ERVV-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59751
MINDY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39382
INTS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20359
Sarcoma_SARC_TCGA-QQ-A5V9-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2990-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.18449
CCNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61385
BT483	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32405
WDR83OS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12282
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.949743
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.80125
H3K36me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FAM171A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34117
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.98275
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5085-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KPNA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94249
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2957
HMBOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25883
OVCA 429	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.08391
Lung squamous cell carcinoma_LUSC_TCGA-L3-A524-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE57871_11_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-SI-A71O-06A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRODH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3307
all	GWASdb SNP-Phenotype Associations	1.0	0.029009
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67V-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HGC-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HE-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29919
DNAJC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4598
GSE131649_6_v_5_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF449	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87376
MZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.01537
SYCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11375
FYCO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98122
PDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4981
ZNF224	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46758
Ventral pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28899
LRRC55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76515
CRACR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02303
H3K36me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPL13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80865
EBF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64069
TMEM132B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79562
KCNQ4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21059
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.83328
AKIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7062
PTGFRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32858
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.857396
RBM43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28695
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
ZNF619	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05471
H3K36me3_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CALD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51855
PMC10806738-mmc2.xlsx-Table_S1-Table_S1_Table_of_significantly_adjusted_p-valued_0_05_up-regulated_genes_log2FC_1_in_MAX-R60Q_transfected_HEK293_cells_relative_to_MAX-WT_transfected_cells_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A1H6-01B-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MW-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.841226
Brain Lower Grade Glioma_LGG_TCGA-DU-A6S8-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SEPTIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56955
GTEx Lung 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	-1.0	-5.38883
ASAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0888
POLR2A	ENCODE Transcription Factor Targets	1.0	null
DNAJB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85699
PLEKHG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49156
primary auditory cortex (core)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.978074
GINM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.453
GPR25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34926
UHO1	DepMap CRISPR Gene Dependency	1.0	3.31687
ZNF101	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58361
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.858428
TRAF3IP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57659
GSE130401_6_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LB-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53438
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.32097
TRAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01794
RTKN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15073
H1_Derived_Neuronal_Progenitor_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.949739
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23615
A1CF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25197
CLPP_KO_GSE40207_378_mouse_Testies	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
JARID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32952
CCR10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4579
TRMT10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41301
ESYT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45123
GSE131649_4_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GCNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01919
ASB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63199
NDUFB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48778
PMC9530161-41419_2022_5296_MOESM2_ESM.xlsx-Tab10_KDM5C-KD-up-DKD-rescued-Table_10_Up-regulated_genes_in_KDM5C-KD_and_rescued_genes_in_DKD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GB-46-CK08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.24429
C3orf14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43708
Nde	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.939
orbital frontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.911899
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PLEC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29124
OAW28	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74285
SAP30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87156
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0783
LN428	CCLE Cell Line Gene Expression Profiles	1.0	1.7502
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.959516
SLC3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98643
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16106
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.2186
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MX-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE128730_4_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
parasubicular cortex (parasubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.02611
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.65772
NCO2	CCLE Cell Line Gene CNV Profiles	1.0	1.92831
CARD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96164
GB2	DepMap CRISPR Gene Dependency	1.0	2.13709
Mesothelioma_MESO_TCGA-LK-A4O6-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRSF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06007
Acute Myeloid Leukemia_LAML_TCGA-AB-2810-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRFAP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18813
MM127	DepMap CRISPR Gene Dependency	1.0	3.25688
Gli1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.6298
UT7	CCLE Cell Line Gene CNV Profiles	1.0	3.01473
HCC70	CCLE Cell Line Gene CNV Profiles	-1.0	-1.72333
RUSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80749
AP4M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62051
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.04157
SNU626	DepMap CRISPR Gene Dependency	1.0	2.3513
Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NN-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPP2R5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42291
SNU1079	DepMap CRISPR Gene Dependency	1.0	2.69126
NCIH1836	CCLE Cell Line Gene CNV Profiles	1.0	2.03424
placenta	HPA Tissue Protein Expression Profiles	1.0	1.1792
ZNF263	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.1145
GSE242290_3_v_2_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.81406
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6YA-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7293
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.925298
Lung adenocarcinoma_LUAD_TCGA-55-7903-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.42568
A_CA_04_2009_4dayMOI-10^5_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.33161
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04832
MYOG_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JURKAT, CLONE E6-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.28344
NPAS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44502
posteroventral (inferior) parietal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.826078
TUBA1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96659
ETFDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18966
SARAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76214
posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.829916
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14177
Autosomal genetic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.852
Lung adenocarcinoma_LUAD_TCGA-86-A456-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SULF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94142
NDUFAF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7873
VAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7818
GSE120216_3_v_0_cbfb_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
769-P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.950763
CAL51	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.840858
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.51998
FGFBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54187
CXCL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12063
GSE60691_2_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SKOV3	CCLE Cell Line Gene CNV Profiles	1.0	1.81914
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12915
TTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41177
BL41	CCLE Cell Line Gene Expression Profiles	1.0	1.35346
UACA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95137
SAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5956
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.6937
ERP29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22333
SCPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32212
PLK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1215
IL13RA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71068
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.5271
EIF2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13092
NCI-H1155	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.991036
GSE131649_4_v_10_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RBM18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60138
TMEM81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17839
CHAGOK1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.16723
C170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02772
UXT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36213
Perturb_15694_OE_NOAT113026_SRP212748	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.44946
SARS-dORF6_48Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.72895
VASP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92707
RGMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27614
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.888674
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.54394
PMC11409756-13062_2024_533_MOESM1_ESM.xlsx-Sheet1-Table_S1_Differentially_expressed_genes_DEGs_regulated_by_ZFP64_through_mRNA-seq_ZFP64	Rummagene Transcription Factor Associations 2026	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-YY-A8LH-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.24861
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2493
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LUZP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35991
GSE221327_1_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
outer SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07877
SCC25	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32005
ZNF763	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91784
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.39
MZ in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.67018
SLC43A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68135
mediodorsal nucleus of thalamus_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.58078
TARDBP_02_129	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.08283
GSE158834_10_v_6_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE114883_0_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.852
AMFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93165
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6551
esophagus	HPA Tissue Gene Expression Profiles	-1.0	-1.34174
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.964288
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2R9-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBC1D15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2357
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.2572
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-gene_id_y_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
Glutathione hydrolase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.773
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10356
inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.892079
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AZ-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KHM1B	CCLE Cell Line Gene CNV Profiles	1.0	1.68456
IGR-37	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.842292
TMEM39B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27172
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.49964
Brain Lower Grade Glioma_LGG_TCGA-FG-A6IZ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZSCAN31	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0579
KLM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52875
H3K36me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23855
GTEx Brain 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	1.0	8.20226
ZNF76	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7979
GSE151782_2_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
inner CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.872166
stratum oriens of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.889764
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.875249
ATP1B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23116
TCF12/HEB-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE193258,GSE193259_5_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HES3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64922
SFMBT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1161
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.23962
SPTBN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08884
Rectum adenocarcinoma_READ_TCGA-DY-A1H8-01A-21R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ES-A2HS-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF592	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58352
USP39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44717
GSE153871_4_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5185-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GRHPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64351
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21023
GON4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76766
NR5A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67849
EW22	DepMap CRISPR Gene Dependency	1.0	2.26094
RKO-E6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.41135
FAM133B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71279
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.53983
outer CP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23014
Brain Lower Grade Glioma_LGG_TCGA-HT-A74K-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCT4-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TFAP2E	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.5024
ZBTB33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66627
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A7-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NT5DC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23748
internal segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.826476
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.46312
PAXX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36064
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.5308
CTCF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	230.081
CEBPB	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K36me3_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62245
CCDC51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60792
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.986678
639-V	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MMP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17802
GSE227127_1_v_0_diclofenac_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GCAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20759
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1703
testis_7f	HPA Tissue Sample Gene Expression Profiles	1.0	1.63164
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_30min-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
ARPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91831
GSE158834_10_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0772
HYAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24503
CTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60521
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
ZNF774	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5808
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.950612
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE202284,GSE202289_3_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EIF4E2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98274
MALME3M	DepMap CRISPR Gene Dependency	1.0	2.5353
MCAS	DepMap CRISPR Gene Dependency	1.0	2.14888
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HDHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73941
MIER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93204
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.5475
CLPP_KO_GDS4791_374_mouse_Testies	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-8585-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE168401_1_v_3_harmine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K36me3_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62024
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.75413
GSE101239_4_v_6_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5107-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF200	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56968
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A4BA-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
spinal trigeminal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.6184
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.857396
GSE220693_1_v_0_cgas_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A952-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SET2	CCLE Cell Line Gene CNV Profiles	-1.0	-2.11089
type 2 diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.970747
u87	HPA Cell Line Gene Expression Profiles	-1.0	-1.45889
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32388
TMEM238	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70379
LZTS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18488
H3K36me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.851718
GSE103068_5_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.271
FGFR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24325
CME1	DepMap CRISPR Gene Dependency	1.0	2.84003
Tfcp2l1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.0485
KLC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16502
YKG1	DepMap CRISPR Gene Dependency	1.0	2.02009
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.83155
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A4ZP-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF692	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	95.7126
GPR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64885
ZC3H7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4411
VZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.828251
TEKT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92586
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02645
Lung adenocarcinoma_LUAD_TCGA-55-1595-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.29783
Brain Lower Grade Glioma_LGG_TCGA-DB-A4XA-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8061-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7203476-Table_2.XLSX-MI_treat_vs_control-Unnamed_0_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
RPRM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28376
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE153871_4_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EOL1	DepMap CRISPR Gene Dependency	1.0	3.68632
SNU1077	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5277
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.841226
tail of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05816
TMEM181	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.387
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
central medullary reticular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1826
rostral subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.5711
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.08162
GPR137	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85382
outer SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04071
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.917913
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A6W2-06A-22R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EXD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43572
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.47177
GSE131649_4_v_5_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-CA-geneName_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1482	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE131649_6_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
lateral hypothalamic area, anterior region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.27918
ARPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60528
arcuate nucleus of medulla, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.933684
PMC11938024-ADMA-37-2413413-s001.xlsx-Table_S1a_DE_Genes_analysis-Table_S1a_Differentailly_expressed_genes_Control_vs_NPs_treated_THP1_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
EMC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06839
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.826963
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.74899
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81A-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.940201
Degeneration of macula and posterior pole	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.852
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53965
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IM-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCFL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.8883
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.82838
Lung squamous cell carcinoma_LUSC_TCGA-60-2726-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JD-81-YX02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211191
GARP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.82
SNU1214	CCLE Cell Line Gene CNV Profiles	-1.0	-2.22464
Lung squamous cell carcinoma_LUSC_TCGA-85-A5B5-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RYK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87796
SNU1076	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6093
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28472
Prostate adenocarcinoma_PRAD_TCGA-G9-6379-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6397-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCAND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29496
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.99862
Pancreatic adenocarcinoma_PAAD_TCGA-FB-A78T-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ERF::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.5314
HCT116	CCLE Cell Line Gene Expression Profiles	1.0	1.63075
HECTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84967
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19P-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PCDHB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43023
F36P	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73466
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF213	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.3945
ARL6IP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6275
Perturb_6734_KO_TOP3B_SRP345494	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.00901
Lung squamous cell carcinoma_LUSC_TCGA-77-8154-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25395
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7UY-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27201
ERGIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62216
TMEM147	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32698
H3K36me3_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.8308
Spz1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.0
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.68947
SIG-M5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.16574
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7X8-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92216
OCUG1	DepMap CRISPR Gene Dependency	1.0	3.79347
RPP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44798
inferior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.36065
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AQ-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MFSD14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41678
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.927463
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.57587
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A852-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7477-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
D423MG	DepMap CRISPR Gene Dependency	1.0	6.46411
Lung adenocarcinoma_LUAD_TCGA-44-A4SU-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1478
bed nucleus of stria terminalis	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18131
CLPP_KO_GSE40207_392_mouse_Testis	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.24747
GSE190316,GSE190324_0_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
CERS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2097
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.33888
GPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45851
PMC12178829-mmc4.xlsx-Sheet_4-MEG3-KD_Up-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE168401_2_v_3_harmine_human	RummaGEO Drug Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.908511
GSE121043_0_v_1_aldh1a1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9424213-41467_2022_32537_MOESM6_ESM.xlsx-siHNRNPK_nuc-DEGs_for_hnRNPK_KD_Nuclear_RNA_of_HeLa_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEx Brain 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	1.0	15.5713
EIF3J	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7752
PRIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52077
gyrus rectus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09602
GSE218378_1_v_0_pbx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ARL14EP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81153
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A63U-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NALM-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.892373
Lung adenocarcinoma_LUAD_TCGA-O1-A52J-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.47893
upper (rostral) rhombic lip_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.19008
ASB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5895
CALU-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.26418
SEPTIN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44267
UCKL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16391
DB	CCLE Cell Line Gene CNV Profiles	1.0	2.07794
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.888927
CHCHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97439
PPP1R11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64472
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.954779
AGRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95411
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15277
ALDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85758
GSE158834_0_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
IGROV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.2561
GSE218960_0_v_1_nrf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
stratum lacunosum-moleculare of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.916491
Sarcoma_SARC_TCGA-DX-AB2J-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1975 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.389
QPRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24094
CYCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50858
C1orf109	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20626
COX6B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92905
PMC12178937-mmc6.xlsx-L_AKAP12_KDvsD_AKAP12_KD_deg_al-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.029036
PPP3CB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49104
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A6HP-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Monogenic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.852
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE215155_0_v_1_golph3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
STARD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11811
HGC27	CCLE Cell Line Gene Expression Profiles	1.0	2.12925
DCAF12L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12837
PCCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82611
RCC4	CCLE Cell Line Gene Expression Profiles	1.0	1.6892
H3K36me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NALM16	DepMap CRISPR Gene Dependency	1.0	2.53343
ZNF79	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96694
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A5PC-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPUSD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13238
H3K36me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12717993-MEC-34-e17796-s002.xlsx-ST12_WGS_RFMix_genes_2_anc-Unnamed_14_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
skin_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.16373
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5ED-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM72A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37952
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.57122
Rectum adenocarcinoma_READ_TCGA-BM-6198-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMSB4X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88445
MYL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57727
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE224969,GSE224971_0_v_7_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
THOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49087
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26162
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4351-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A8HX-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD248	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90024
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.64977
C14orf28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37053
abnormal glucose homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.241331
NCI-H520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.5111
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05937
testis_7e	HPA Tissue Sample Gene Expression Profiles	1.0	1.98629
CLPP_KO_GDS4791_537_mouse_testis	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-A4M7-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AN3CA	CCLE Cell Line Gene Expression Profiles	1.0	1.59194
GSE125014_6_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Prdm15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	49.4832
Acute Myeloid Leukemia_LAML_TCGA-AB-2920-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IFT20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53266
NCIH1437	DepMap CRISPR Gene Dependency	1.0	2.34556
NCIH1876	CCLE Cell Line Gene Expression Profiles	-1.0	-1.55753
TRMT61A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79567
GSE164757,GSE164759_1_v_0_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRI3BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59069
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51K-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100606_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.42337
WM88	DepMap CRISPR Gene Dependency	1.0	2.40993
PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_12613_KD_SON_SRP278179	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
PMC9336541-Table_3.XLSX-C-vs-H6-L_filter_annot-Unnamed_18_HMX1	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96443
DBTRG05MG	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52341
GSE185922_1_v_2_riok2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF510	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71408
GSE140936,GSE140938_2_v_1_slfn11_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Eye degenerative disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.852
H3K36me3_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
type ii diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.855091
small intestine	HPA Tissue Protein Expression Profiles	1.0	1.1792
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.942272
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SH-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DCAF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47879
MDA-MB-453	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.939682
Lung adenocarcinoma_LUAD_TCGA-44-A47A-01A-21R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4638-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.37117
NOLC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81065
superior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.841482
Eye disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.852
TMEM191B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16763
GNG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64186
GSE242290_1_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CHD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36837
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.834873
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-95-7944-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCCLMS1C1	DepMap CRISPR Gene Dependency	1.0	2.0676
CASTOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17335
cingulate gyrus, frontal part, left, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0133
CCDC106	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87918
JHOC5	DepMap CRISPR Gene Dependency	1.0	2.28393
ZNF524	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1133
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4822-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03272
MCTS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49044
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.3434
GMPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85234
GSE236280_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IGR-37	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.15247
H2BC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59098
Brain Lower Grade Glioma_LGG_TCGA-DU-7304-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GOLGA6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38285
parahippocampal gyrus, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11543
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.35716
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rhinovirus infection_Nose_GSE11348	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.69626
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PM-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13388
SLC1A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9803
EGI1	DepMap CRISPR Gene Dependency	1.0	3.56763
CSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79178
PRICKLE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31379
SPG11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69287
KIZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46488
Prostate adenocarcinoma_PRAD_TCGA-V1-A8MM-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE234514,GSE234516_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Gli2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.4482
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08282
PMC11653668-ADVS-11-2400133-s005.pdf-6-ZNF777_ZNF777	Rummagene Transcription Factor Associations 2026	1.0	null
UKE-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.956752
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A7HU-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.825326
GSE106661,GSE106665_0_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040355
GSE130401_4_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SPRYD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45485
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.64221
FXYD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90273
VIIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.935778
outer CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.6973
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE120612_7_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE242290_3_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.894483
glucose metabolism disease	GWASdb SNP-Disease Associations	1.0	0.321978
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.16301
TRAF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84295
IZ in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16513
PIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52367
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6K1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
esophagus_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.979731
MZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.883502
UBTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79492
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-58-8387-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A_CA_04_2009_4dayMOI-10^4_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.31943
ODF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.02435
SMURF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90719
SNU46	CCLE Cell Line Gene Expression Profiles	1.0	3.36375
SNU119	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5087
NUDHL1	CCLE Cell Line Gene Expression Profiles	1.0	1.37235
NAA20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35186
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A71R-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ANKRD13B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67755
GABRA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5047
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.96816
MZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.78156
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.2652
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.895002
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F5-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-NJ-A4YI-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60058
dorsomedial hypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12043
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.28813
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.44497
SAMM50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79697
CERCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31329
PXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9349
inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09979
Acute Myeloid Leukemia_LAML_TCGA-AB-2882-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TTLL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91683
Adrenocortical carcinoma_ACC_TCGA-OR-A5LD-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PFDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29278
TAL1-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RWDD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45785
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L8-01A-21R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RANGRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2551
superior colliculus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.26493
MKN74	CCLE Cell Line Gene CNV Profiles	-1.0	-2.91532
Prostate adenocarcinoma_PRAD_TCGA-V1-A8WV-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PNMA8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85168
hippocampus (hippocampal formation)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.47883
KE37	DepMap CRISPR Gene Dependency	1.0	2.25233
external segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03808
Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-11A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.919936
Perturb_17282_KO_Hsf5_SRP345601	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
SGPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21202
A-431	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.95096
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8396
TFAP2E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6281
inner CP in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.886434
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.845376
PLAG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	250.444
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OY-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CKMT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88018
GP2D	CCLE Cell Line Gene Expression Profiles	1.0	1.41378
COLO775	CCLE Cell Line Gene Expression Profiles	1.0	1.51507
GOLGA6L9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33337
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.10718
NCIH596	CCLE Cell Line Gene Expression Profiles	-1.0	-1.78511
Lung squamous cell carcinoma_LUSC_TCGA-43-8118-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.938485
Wt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	62.6449
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.00441
abnormality of metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.056407
Prostate adenocarcinoma_PRAD_TCGA-WW-A8ZI-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Aorta	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-2.15533
GSE234334,GSE234336_1_v_0_zhx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DYNLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30951
SK-OV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.2105
MOLM16	CCLE Cell Line Gene CNV Profiles	1.0	2.36466
GSE203308_9_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11225427-13058_2024_1861_MOESM2_ESM.xlsx-Supplemental_Table_S4-Supp_Table_S4_AR_mediated_PGx-eQTL_genes_and_associated_with_all_GWAS_traits_from_GWAS_catalog_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Inflorescence stalk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.244
inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17275
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IL-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-WP-A9GB-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFO21	CCLE Cell Line Gene Expression Profiles	1.0	1.44519
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3346-01A-01R-1766-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1532
Kidney Chromophobe_KICH_TCGA-KL-8327-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
X, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.40846
UCK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29716
PMC10214295-mmc4.xlsx-A_-_Human_Islets_ZBTB16_targets-Ensembl_Gene_ID_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.833735
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A55Z-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33082
GSE88819_1_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4P0-01A-41R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTTNBP2NL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0107
MCOLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1287
LS513	DepMap CRISPR Gene Dependency	1.0	2.08231
GSE107505_1_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Zfx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	45.6311
medial parabrachial nucleus,right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17009
Flower stalk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.442
TFAP2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	196.303
KIF5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80057
FANCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32228
OAW28	CCLE Cell Line Gene Expression Profiles	-1.0	-1.9459
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.91505
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5UM-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K36me3_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYCBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46674
GSE242290_1_v_2_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00922
Lassa Fever Virus_4hr_24069471_GSE41300	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.08458
ZNF597	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00691
MMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56132
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.4895
EB1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.987751
HJURP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30918
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.45718
NPRL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45152
NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.2746
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00947
hippocampus (hippocampal formation)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14108
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.54173
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.886586
GSE248858_4_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
UBE2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63733
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.867633
PRR35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4966
CHAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63885
PMC3910540-725780.f1.xlsx-Table_S5-MYC_target_genes_in_human_ES_cells_Ji_Wu_et_al_2011_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
IKZF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64825
ELF1	ENCODE Transcription Factor Targets	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.863073
KIFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50637
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.6884
GCM2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4587
DUSP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14805
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MB-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21972
HC-74-HM63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.219209
GSE158834_10_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
TP53I13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56761
H3K36me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MSC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17065
SH3YL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26355
TNKS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61992
Lung adenocarcinoma_LUAD_TCGA-MN-A4N4-01A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SAP18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6787
WIPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54211
DBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2331
MED12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1988
Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4U1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GNG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02229
GTPBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31355
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WP-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.87521
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AP-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KIF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91674
lateral medullary reticular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0807
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1715
hippocampus (hippocampal formation)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.97305
CCDC87	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6947
CSNK2A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86025
anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04452
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.66789
MYH14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44772
NRBF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20808
Prostate adenocarcinoma_PRAD_TCGA-HC-7752-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.863073
H1 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.992299
cerebellar cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.53405
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.944837
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.868265
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A4XJ-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PROX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59784
HOXC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2042
karpas707	HPA Cell Line Gene Expression Profiles	-1.0	-2.39936
CTSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67338
ZNF462	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65597
midbrain reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.21878
SLC2A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3858
H3K36me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLF4-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PK-59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52298
PIK3R3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05214
ENTPD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72628
MYO18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34277
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.988747
Lung squamous cell carcinoma_LUSC_TCGA-L3-A4E7-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-IZ-A6M9-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6379364-41598_2018_37489_MOESM2_ESM.xlsx-Sheet2_DESeq_MSC_vs_fibroblast-DESeq_MSC_vs_fibroblast_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
USP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0381
Head and Neck squamous cell carcinoma_HNSC_TCGA-T2-A6WX-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4341-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-KR-A7K2-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00983
GSE196835_0_v_1_ddx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HOXC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1613
ZNF329	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17551
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01886
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.01546
TDGF1P3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43579
HOXC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97333
PLPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73913
amygdaloid complex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19256
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.05293
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-A5NJ-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.85836
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.25559
SNU1066	DepMap CRISPR Gene Dependency	1.0	2.09042
NPDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87887
Ebolavirus(EBOV)_5day_Splenocytes_19683682_GSE17509	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.93075
ZNF343	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42245
MPLKIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.94046
FUT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74353
TTLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23845
Lung squamous cell carcinoma_LUSC_TCGA-34-7107-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRGBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21312
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10455
H3K36me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FLII	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16954
MLH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41677
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80Q-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SYCE1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16282
UMRC3	DepMap CRISPR Gene Dependency	1.0	2.34913
UNC5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79918
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.842759
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18125
MEX3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29703
orbital frontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.963395
CUL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29383
IZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21956
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HO-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH929	CCLE Cell Line Gene CNV Profiles	1.0	1.58395
GSE162892_4_v_5_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-8640-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AQ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE242290_3_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ACTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06893
SMARCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86439
GFER	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47354
SIVA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29925
SPIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33099
primary motor cortex (area M1, area 4)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03607
POLR2AphosphoS5_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-4625-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.23042
Perturb_1348_KD_RAC3_SRP368300	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.28215
GATAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97155
Brain Lower Grade Glioma_LGG_TCGA-R8-A73M-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE217776,GSE217829_2_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-Q3-AA2A-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.89624
testis_7a	HPA Tissue Sample Gene Expression Profiles	1.0	1.71102
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5469-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.968456
PK59	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7479
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41002
HC-74-HM63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.244047
ELK1	JASPAR Predicted Transcription Factor Targets	1.0	null
MEG01	CCLE Cell Line Gene CNV Profiles	1.0	1.63105
BRME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57963
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1364
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Autosomal dominant disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.852
C15orf39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00018
EJM	DepMap CRISPR Gene Dependency	1.0	3.21199
L363	CCLE Cell Line Gene CNV Profiles	1.0	1.3334
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4981-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0001
Guard cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.833
RNF208	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76581
496100670_TCx_probable Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.90125
DNAJB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62685
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.9861
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.5402
GSE173394_1_v_0_nfatc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.872134
ZNF483	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16355
GSE95077_1_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
RIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06445
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.836163
VEZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.5863
BRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55191
PMC9160255-41467_2022_30710_MOESM4_ESM.xlsx-AR_specific_regulated_genes-SYMBOL_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20P-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.05913
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.09135
ONDA9	DepMap CRISPR Gene Dependency	1.0	3.21914
GARIN1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07281
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF713	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39699
DDX42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4004
FAIM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12272
rostral division of OFCi (area 11)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.87103
FC-20-EQ58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.354046
FF-06-MO73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.206755
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A23K-01A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-MP-A4TD-01A-32R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VPS35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21934
ovary_8a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.11295
RPL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87616
ATP11C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18733
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A763-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Retinal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.852
YWHAZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54082
SOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99377
SNU685	CCLE Cell Line Gene Expression Profiles	-1.0	-2.15315
orbital frontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.34419
Bladder Urothelial Carcinoma_BLCA_TCGA-MV-A51V-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5001-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.51091
TASK1	DepMap CRISPR Gene Dependency	1.0	2.0499
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TA-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIM33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35081
CCNC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63023
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-3.41306
NCIH520	CCLE Cell Line Gene Expression Profiles	1.0	2.39653
ZBED2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.377
MYCN-27167114-CHIP-SEQ-NEUROBLASTOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-A4BD-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.41739
paracentral lobule, anterior part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.40344
CTCF	ENCODE Transcription Factor Targets	1.0	null
OVCA420	DepMap CRISPR Gene Dependency	1.0	2.96977
RNF170	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.71153
KDM5B	ENCODE Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DH-A669-02A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19568
KMS27	CCLE Cell Line Gene CNV Profiles	1.0	1.59259
CENPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.87922
NFXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30766
LRIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75811
KDM5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6998
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39037
APOE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82522
VMRCLCD	DepMap CRISPR Gene Dependency	1.0	2.2859
C17orf58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39327
BCL7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58
SREBF1	JASPAR Predicted Transcription Factor Targets	1.0	null
MOLM14	DepMap CRISPR Gene Dependency	1.0	3.80151
ALKAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84992
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.60673
MCRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31524
HS 578T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.09432
ME-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.25716
COLO-704	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22115
GSE221327_5_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE199204,GSE211619_4_v_3_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_1day-MOI-10^4_None_GSE44441	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.63184
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.87548
NAT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14313
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.06166
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.857396
HLA-C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92824
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04204
NB6	DepMap CRISPR Gene Dependency	1.0	2.88934
MFF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99543
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04204
MOLM13	DepMap CRISPR Gene Dependency	1.0	3.49594
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6V7-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEF2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96576
paraventricular nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.53045
CHMP4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19359
Ebolavirus(EBOV)_3day_Splenocytes_19683682_GSE17509	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.34913
GSE214823,GSE214824_5_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K36me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46189
PRXL2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5807
TPSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15142
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.835199
EZH2	ENCODE Transcription Factor Targets	1.0	null
spleen	HPA Tissue Gene Expression Profiles	1.0	0.996006
GSE203308_15_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.908669
SNTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99942
OGG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4368
Kidney renal clear cell carcinoma_KIRC_TCGA-MM-A84U-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
L428	DepMap CRISPR Gene Dependency	1.0	2.95418
Thymus	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.06884
ZNF668	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85367
MAP4K5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27816
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04301
BEN	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47563
Lung adenocarcinoma_LUAD_TCGA-NJ-A4YF-01A-12R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3YL-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23454
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.23567
FAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45107
GSE216540_0_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Dhori Virus_24Hour_20090954_GSE17400	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.13944
ZNF721	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89135
IRGQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5634
posteroventral (inferior) parietal cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11778
Lung adenocarcinoma_LUAD_TCGA-69-8255-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7825356-8844261.f3.docx-155-CREB3L3_CREB3L3	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45Q-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE140936,GSE140938_0_v_1_slfn11_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0337
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1128
ZNF710	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34387
REC1	CCLE Cell Line Gene CNV Profiles	1.0	1.79024
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.48574
Lung squamous cell carcinoma_LUSC_TCGA-43-3394-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.67275
Renal cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.127
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03261
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21304
MPHOSPH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.34697
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01536	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.3523
GSE248858_1_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ECC2	DepMap CRISPR Gene Dependency	1.0	2.30968
PMC12522211-NIHMS2104691-supplement-MMC1.xlsx-SRCAP_DE_genes-Gene_SRCAP	Rummagene Transcription Factor Associations 2026	1.0	null
GSE123861_1_v_0_sin3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.857396
UMRC6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48497
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.964288
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.64292
VCAP	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36332
NICN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44003
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.953432
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.862098
POLR2AphosphoS2_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.64378
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
E2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.4947
testis_7d	HPA Tissue Sample Gene Expression Profiles	1.0	1.48533
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28574
ATP6V0E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02748
USF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19076
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.64827
SIRT6	ENCODE Transcription Factor Targets	1.0	null
primary auditory cortex (core)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.15944
ACSL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61999
NCIN87	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7914
DUSP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30227
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.30275
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5319
H3K36me3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMT2E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96052
P30OHK	DepMap CRISPR Gene Dependency	1.0	2.36213
CALU-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.35154
ZCRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03706
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14177
ILF2_02_88	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.05889
FHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18539
U2AF1L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06644
CCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.74936
PLSCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32771
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.84688