association dataset threshold value standardized value Inferior olivary complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29319 parasubicular cortex (parasubiculum) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03567 Sarcoma_SARC_TCGA-X6-A7WC-01A-12R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SP3_Deficiency_GDS3058_610_mouse_Embryonic heart (day 12.5 C57Bl/6) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Bed nuclei of the stria terminalis, anterior division, juxtacapsular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.40671 H3K9me3_Fetal Brain Roadmap Epigenomics Histone Modification Site Profiles 1.0 null UBTFL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22889 hsa-let-7f TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 subcallosal cingulate gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.35829 NCIH716 CCLE Cell Line Gene CNV Profiles -1.0 -1.33529 CW-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCIH2081 CCLE Cell Line Gene CNV Profiles 1.0 1.52279 SUPT6H CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68747 CTCF_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KYSE180 CCLE Cell Line Gene CNV Profiles 1.0 1.39902 icSARA deltaORF6_30Hour_23365422_GSE33267 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.55813 COQ8B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42339 496100499_PCx_no dementia_no TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.93732 HCC202 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.946228 skin disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.945428 CTCF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 204.331 GRK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58553 hsa-miR-599 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 GCM2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.3596 Endopiriform nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37627 hsa-miR-3714 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 CCDC85B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0969 AN3-CA COSMIC Cell Line Gene Mutation Profiles 1.0 null PPP1CA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.97212 H3K9me3_G1E-ER4_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null HEY2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26964 GSE207514,GSE207515_2_v_3_acetylcysteine_human RummaGEO Drug Perturbation Signatures -1.0 null STAT3 ENCODE Transcription Factor Targets 1.0 null GJD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34505 Disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.984 HINFP JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.708 NUGC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.873184 SRSF7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.21403 Skeletal Muscle Female Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 0.884015 GSE240386,GSE242143_8_v_6_morc2_human RummaGEO Gene Perturbation Signatures 1.0 null H3K9me3_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perihypoglossal nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43453 r5 (gustatory) part of solitary complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29559 RDES CCLE Cell Line Gene CNV Profiles -1.0 -1.62284 LRRC55 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.76515 ZDHHC5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96565 KCTD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.93172 amygdalostriatal transition area Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.57477 Attention deficit hyperactivity disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.079 mammillary body, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.18603 stratum radiatum of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.847686 Brain Lower Grade Glioma_LGG_TCGA-CS-5394-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ACOT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06413 periventricular stratum of r2BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.61985 SG in rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.15147 U-2932 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.51624 GSE214382,GSE214383_5_v_2_ascl1_human RummaGEO Gene Perturbation Signatures 1.0 null Paraflocculus, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.88233 Central amygdalar nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23637 Rectal Mucosa Donor 31 Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 0.917388 LRPAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38537 RPH3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53027 496100651_FWM_probable Alzheimer's disease_TBI_83_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.95173 TOV-112D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.873184 REH DepMap CRISPR Gene Dependency 1.0 2.00492 CTCF_CH12.LX_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100326_TCx_no dementia_TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.28146 NCIH2085 CCLE Cell Line Gene CNV Profiles 1.0 2.29289 medial (magnocellular) part of MD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16396 hypoglossal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.57002 PC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.03795 Brain Lower Grade Glioma_LGG_TCGA-FG-A4MX-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Entorhinal area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19638 NRBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36633 TTC19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.50221 icSARS CoV_48Hour_23365422_GSE33267 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.83042 terete nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1332 PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_3_CTCF Rummagene Transcription Factor Associations 2026 1.0 null EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null C19orf47 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3997 NCI-H23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08735 HT115 DepMap CRISPR Gene Dependency 1.0 5.88493 superficial stratum of r9Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36337 STAT3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.1151 PKNOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.5399 Uncharacterised protein family UPF0572 InterPro Predicted Protein Domain Annotations 1.0 null FOXE3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18518 hsa-miR-432 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 TRAPPC8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34575 MYLIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78605 Central amygdalar nucleus, capsular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04467 H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ACD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7402 precuneus, left, superior lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.845038 intercalated amygdaloid nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.245 SNU-484 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03756 hsa-miR-4763-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.945428 hsa-miR-548k TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 UMUC7 DepMap CRISPR Gene Dependency 1.0 3.06491 layer 3 of AOD cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51859 integumentary system disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.945428 SNU-449 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.873184 ventral tegmental area Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.938812 CTCF_lung_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CEBPB ChEA Transcription Factor Targets 1.0 null GSDMB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.17401 r8 part of the trigeminal column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15438 superior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.22916 Entorhinal area, lateral part, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.71758 Primary hematopoietic stem cells G-CSF-mobilized Female RO_01508 Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.44858 H3K4me1_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null LN-18 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09776 Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Z-11A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-1273f TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 H3K9me3_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null LRP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44991 hsa-miR-3201 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 intermediate stratum of APal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.69847 GSE182680,GSE182683_0_v_8_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null Retrosplenial area, lateral agranular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39072 SFR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78699 ONCODG1 CCLE Cell Line Gene CNV Profiles 1.0 1.94083 Muscular system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 ANP32D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.11712 RAD21_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RVH421SKINFV1 DepMap CRISPR Gene Dependency 1.0 2.10411 Piriform-amygdalar area, pyramidal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33281 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73S-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5559-01A-01R-1514-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null medial pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39456 Koelliker-Fuse nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41816 FOSL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.72191 MZ in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.23789 ZBTB11 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.5044 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A954-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Hair disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.984 icSARA deltaORF6_60Hour_23365422_GSE33267 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.28252 IZ in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.890832 CTCF_ES-Bruce4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC15 CCLE Cell Line Gene CNV Profiles -1.0 -1.78897 Paraventricular hypothalamic nucleus, magnocellular division, medial magnocellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.36986 Entorhinal area, medial part, ventral zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00301 hsa-miR-1185 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 MZ in caudal cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.847686 BAZ1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55682 MDAMB231 CCLE Cell Line Gene CNV Profiles -1.0 -1.34027 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Paraventricular hypothalamic nucleus, magnocellular division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26159 CHP212 DepMap CRISPR Gene Dependency 1.0 2.18866 L1236 DepMap CRISPR Gene Dependency 1.0 3.4043 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6324-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NDUFAF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7873 Prostate adenocarcinoma_PRAD_TCGA-HC-7078-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1143 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.995039 Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8311-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intermediate stratum of p3ZL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1066 Prostate adenocarcinoma_PRAD_TCGA-EJ-7789-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-11A-12R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TMEM134 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30439 KURAMOCHI DepMap CRISPR Gene Dependency 1.0 3.48497 ES2 DepMap CRISPR Gene Dependency 1.0 2.24853 lateral habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.880758 transverse gyri, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.21259 Bed nuclei of the stria terminalis, anterior division, anterolateral area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.07371 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LI-01A-11R-A32Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MOSPD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08974 Entorhinal area, medial part, ventral zone, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0149 KYSE-270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.36566 GSE151612_0_v_7_pracinostat_human RummaGEO Drug Perturbation Signatures 1.0 null SW1783 CCLE Cell Line Gene CNV Profiles -1.0 -2.32404 hsa-miR-1911 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 ZNF778 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91033 tcf12_20154672_cd4pos_cd8pos_thymocytes_thymus_lof_mouse_gpl6246_gse19923 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.022062 MED25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19443 GSE178267_2_v_0_vemurafenib_human RummaGEO Drug Perturbation Signatures 1.0 null posterodorsal tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.77505 caudal subdivision of medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.991549 GCFC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86714 HIF1AN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14777 SNU-C5 COSMIC Cell Line Gene Mutation Profiles 1.0 null HYLS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30153 spinal trigeminal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.59355 caudal presubiculum (postsubiculum) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.75616 inner CP in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.11616 LP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09138 GSE102505_1_v_2_tunicamycin_human RummaGEO Drug Perturbation Signatures 1.0 null CTCF ENCODE Transcription Factor Targets 1.0 null JHH6 CCLE Cell Line Gene CNV Profiles -1.0 -1.8124 STAT3_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH146 CCLE Cell Line Gene CNV Profiles 1.0 1.36948 oval paracentral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50127 MRM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1509 SEPHS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54732 SG in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.01841 MYOG ENCODE Transcription Factor Targets 1.0 null SAP30L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91505 Abducens nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0998 Retrosplenial area, lateral agranular part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.40317 Prostate adenocarcinoma_PRAD_TCGA-HC-7080-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Main olfactory bulb, glomerular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37144 OVISE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.868479 EKVX CCLE Cell Line Gene CNV Profiles -1.0 -1.33346 MFF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99543 SNU478 DepMap CRISPR Gene Dependency 1.0 2.74188 ERF::FIGLA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.4719 hsa-miR-570 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 CCDC28A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14572 H3K9me3_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null inner CP in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.41045 PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_3_CTCF Rummagene Transcription Factor Associations 2026 1.0 null NCOR-22424771-293T-HUMAN ChEA Transcription Factor Targets 2022 1.0 null CIDEA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73519 CTCF_embryonic fibroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_kidney_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null outer SZ in midlateral extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.20064 H3K9me3_U2OS_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_CH12.LX_mm9_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null intermediate stratum of r10Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29418 Entorhinal area, medial part, ventral zone, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05117 496100626_FWM_no dementia_TBI_86_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.96231 GPBP1L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74624 ZNF654 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4783 BFTC-909 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.984459 hsa-miR-4722-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 hsa-let-7i TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 r9 part of spinal trigeminal nucleus, interpolar part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38922 TFCP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.10801 QRSL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34554 SYN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22533 H3K4me3_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null OUMS-23 COSMIC Cell Line Gene Mutation Profiles 1.0 null RH41 CCLE Cell Line Gene CNV Profiles 1.0 1.40395 GXYLT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4317 hsa-miR-335 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 HMCES CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89816 basolateral amygdaloid nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.47531 dorsomedial hypothalamic nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.35477 HCC1576 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09776 TFB2M CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82784 POLR2A_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null fertilizedegg BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 septal organ BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.02832 RAB9A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69167 GSE147366_1_v_0_med13_human RummaGEO Gene Perturbation Signatures -1.0 null IGROV-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.24744 r7 part of nucleus prepositus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24564 hsa-miR-128 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 SQ1 CCLE Cell Line Gene CNV Profiles 1.0 1.33837 MYCN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25429 intermediate stratum of m1AL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.80767 BCAS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27404 precommissural nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.17696 Retrosplenial area, lateral agranular part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.32031 SK-MEL-28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26687 Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BCL6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.9608 OVCAR-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03756 intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null ZNF528 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.9221 r10 basal plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23211 RAPGEF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95265 mRNA_NR2F2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70K-01A-12R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ARHGEF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55757 RILPL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21253 POLR2A ENCODE Transcription Factor Targets 1.0 null CTCF_MEL cell line_mm9_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null HSPA12B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69252 H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null A-VN-1203-2004(H5N1)_Day1-10^2pfu_22074594_GSE33263 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.2609 CAPRIN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.06399 H3K4me3_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE185519_3_v_7_gilteritinib_human RummaGEO Drug Perturbation Signatures 1.0 null occipito-temporal gyrus, left, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.948437 periventricular stratum of DTTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19429 GSE229580_2_v_3_creb1_human RummaGEO Gene Perturbation Signatures 1.0 null SLC39A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69703 r4 part of pontine raphe cell population Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00886 H3K4me3_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MYC_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Subparaventricular zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18274 KELLY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.27064 Bed nuclei of the stria terminalis, anterior division, oval nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13908 intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null NB7 COSMIC Cell Line Gene Mutation Profiles 1.0 null r5 part of posteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12669 superficial stratum of m1AD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10578 EWS502 CCLE Cell Line Gene CNV Profiles -1.0 -1.54613 COLO-678 COSMIC Cell Line Gene Mutation Profiles 1.0 null Primary somatosensory area, lower limb, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20959 Prostate adenocarcinoma_PRAD_TCGA-HC-7745-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lateral dorsal nucleus of thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51R-06A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4727-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 ANKRD28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31679 Brain Lower Grade Glioma_LGG_TCGA-IK-8125-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-147 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 SUZ12-20075857-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Paraventricular hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0435 stomach HPA Tissue Protein Expression Profiles 1.0 1.18259 NCI-H460 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09911 SK-MEL-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.0389 GSE201657_0_v_1_ash2l_human RummaGEO Gene Perturbation Signatures 1.0 null H2AC20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4258 superior frontal gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.13813 928 MEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.089 CHEK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88769 NB1 CCLE Cell Line Gene CNV Profiles -1.0 -2.41409 hsa-miR-491-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 island of Calleja major Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.77949 SNU13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8138 dorsal lateral geniculate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.903168 MYF6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.9641 MYDGF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01638 RI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.950064 NDUFA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01001 dactinomycin_mus musculus_gpl6246_gse21233 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null olfactorybulb BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.00687 H3K4me3_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MZ in dorsomedial parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.31809 U2OS CCLE Cell Line Gene CNV Profiles -1.0 -1.51243 TRIM37 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13154 layer 1 of ERCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.89874 PROX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.1656 G61 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09776 A4/FUK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.874126 THAP1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.573 ventricular (matrix) zone of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.1144 H3K27me3_megakaryocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Retrosplenial area, lateral agranular part, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07523 H3K9me3_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null COR-L279 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.4468 hsa-miR-4294 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 ZNF528 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60452 Primary somatosensory area, lower limb, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00989 NCI-H146 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.868479 hsa-miR-202 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 FAM181B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24489 bonemarrow BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.868511 Intercalated amygdalar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42391 Interanteromedial nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20053 NCI-H28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.984459 TTC709 DepMap CRISPR Gene Dependency 1.0 2.49438 LS-411N COSMIC Cell Line Gene Mutation Profiles 1.0 null DB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.47508 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EK-01A-12R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LYPLA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06926 PANC 04.03 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18543 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GK-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-FR-A726-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RAB3A_KO_GDS2483_700_mouse_Cortex GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null NCCIT COSMIC Cell Line Gene Mutation Profiles 1.0 null ACSM4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34649 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7424-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC9170563-12885_2022_9665_MOESM3_ESM.docx-0-Candidata_target_genes_of_CEBPB_6_CEBPB Rummagene Transcription Factor Associations 2026 1.0 null GSE119978,GSE180930_6_v_4_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null NCI-H345 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.34595 anterior orbital gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.25132 roof plate of p2 (epithalamic roofplate) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.47874 hsa-miR-616 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 NFIX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.4715 COLO 794 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.995804 organelle LOCATE Predicted Protein Localization Annotations 1.0 null hsa-miR-196b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 GSE155567_2_v_0_cd33_human RummaGEO Gene Perturbation Signatures 1.0 null inner CP in midinferior temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.971873 SNU503 CCLE Cell Line Gene CNV Profiles 1.0 2.19461 KYSE-180 COSMIC Cell Line Gene CNV Profiles 1.0 2.64759 KYSE270 CCLE Cell Line Gene CNV Profiles 1.0 2.04483 Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A6I3-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9me3_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null HCC1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.16332 496100324_FWM_no dementia_TBI_79_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.92077 PSMC3IP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04533 inner CP in dysgranular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.13983 NR2C2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.8259 hsa-miR-920 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CL-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Medial preoptic nucleus, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.62729 H3K9me3_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null episupraoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1325 TE5 CCLE Cell Line Gene CNV Profiles 1.0 1.63662 RNH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77208 ELK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8175 mantle zone of LAP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02588 Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4223-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NIH:OVCAR-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.4468 layer VI of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.40909 TGIF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.3941 TAF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.795 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NN-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Tuberomammillary nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3039 MBTD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.04878 ITK_knockout_242_GSE12465 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.29577 TNS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74201 Intermediodorsal nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41651 laterodorsal part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.863594 Extracellular ferritin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.467 substantia innominata/basal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15438 Uterine Carcinosarcoma_UCS_TCGA-N5-A4RN-01A-12R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AG-06A-31R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COR-L47 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.7821 hsa-miR-4686 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 Brain Lower Grade Glioma_LGG_TCGA-S9-A89V-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SG in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.998674 MGRN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5081 occipital pole, left, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.32577 H3K4me1_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Entorhinal area, medial part, dorsal zone, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38737 hsa-miR-4458 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IG-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intermediate stratum of VTTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.35729 CTCF_cortical plate_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null retrohypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00753 Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17468 HCC1534 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.37185 COLO 741 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.946228 Entorhinal area, lateral part, layer 2a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25145 ATXN7L3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82286 SNU-423 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.984459 MYCN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.6816 H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Pyramus (VIII), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00415 TGIF2LY JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.0378 SH3GLB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69872 HAPSTR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53655 GSE190761_0_v_1_samd1_human RummaGEO Gene Perturbation Signatures 1.0 null NCI-H630 COSMIC Cell Line Gene Mutation Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DB-5275-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-7641-01B-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDA-MB-435 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.82507 hsa-miR-4292 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 GRHL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.63941 skeletalmuscle BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.23184 SLC2A4RG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.8945 medial part of r5B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44904 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A7IP-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sperm glycocalyx COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.158 Ansiform lobule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23497 Lung adenocarcinoma_LUAD_TCGA-MN-A4N1-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE172146_2_v_0_mettl1_human RummaGEO Gene Perturbation Signatures 1.0 null J82 DepMap CRISPR Gene Dependency 1.0 2.3578 nucleus incertus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16272 stratum radiatum of caudal CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.78553 SNPH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5406 CCDC177 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11927 posterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.12746 G130 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.54461 Reactive cutaneous fibrous lesion DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.862 Uterine Carcinosarcoma_UCS_TCGA-N5-A59E-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TGIF2LX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.9186 TMEM41B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.77594 HEC-1-A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.874126 KARPAS422 DepMap CRISPR Gene Dependency 1.0 5.55586 HCT-116 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE147366_1_v_4_med13_human RummaGEO Gene Perturbation Signatures -1.0 null abducens nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.932957 CHAC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.84205 periventricular stratum of TPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34353 IGSF9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9006 SLC50A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70242 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5885-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ERRalpha_Deficiency_GDS2727_646_mouse_Heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null H3K27me3_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NCI-H520 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.69217 STAT1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.706 SCC15 CCLE Cell Line Gene CNV Profiles 1.0 1.77573 hsa-miR-3688-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 SG in dysgranular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.19983 HGC-27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.19992 JM1 DepMap CRISPR Gene Dependency 1.0 2.79346 layer I of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.12283 lateral trapezoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48559 GSE119978,GSE180930_0_v_4_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null NCI-H1417 COSMIC Cell Line Gene Mutation Profiles 1.0 null IKZF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68904 Brain Lower Grade Glioma_LGG_TCGA-DU-8168-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null STRADA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02117 supramarginal gyrus, left, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.940464 CA4 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.0102 Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A9PE-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-641 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 centromedian nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.953179 r8 (gustatory) part of solitary complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03097 lateropallial amygdalopiriform area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02528 NCI-H2085 COSMIC Cell Line Gene CNV Profiles 1.0 2.64759 ZNF681 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25048 H3K9me3_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null ICC2 DepMap CRISPR Gene Dependency 1.0 3.19564 BICR18 CCLE Cell Line Gene CNV Profiles 1.0 2.59983 hsa-miR-376c TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 RBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.11139 TNKS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50383 Crus 2, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32128 TADA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83335 DDX42 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37235 hsa-miR-4425 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 EFL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95468 superior olivary complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.938472 angular gyrus, left, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.937413 A-431 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.31612 lateral orbital frontal cortex (area 12/47) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.19486 H3K4me3_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H2122 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09776 periventricular stratum of r5Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29418 EFM-19 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.32946 hsa-miR-1825 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_3_CTCF Rummagene Transcription Factor Associations 2026 1.0 null ZNF469 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9927 superior occipital gyrus, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.969201 LOUNH91 DepMap CRISPR Gene Dependency 1.0 5.86471 upper limb region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.4151 RCCFG2 DepMap CRISPR Gene Dependency 1.0 3.04002 STARD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29109 layer 4 of ERCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.82343 PDX1 JASPAR Predicted Transcription Factor Targets 1.0 null H3K27me3_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null superficial stratum of r9BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16932 r6 part of basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00886 HRH3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13004 H3K9me3_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null 496100596_FWM_dementia_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.05007 interpositus (intermediate) nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.13344 MSX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8096 Lung adenocarcinoma_LUAD_TCGA-55-8614-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PANC 05.04 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.874337 spleen BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.11608 hsa-let-7d TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 NCIH2141 CCLE Cell Line Gene CNV Profiles -1.0 -1.54439 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FM-8000-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC2885 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.984459 H3K27me3_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9me3_Neurosphere Cultured Cells Cortex Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K27me3_Pancreatic Islets Roadmap Epigenomics Histone Modification Site Profiles 1.0 null hsa-miR-3679-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 TFAP4::ETV1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 67.4989 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A114-11A-12R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EH-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SP in rostral midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.15586 SNX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0911 CAL-51 COSMIC Cell Line Gene Mutation Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MA-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.945428 LS DepMap CRISPR Gene Dependency 1.0 3.77038 hsa-miR-371b-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 H3K9me3_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_3_JUN Rummagene Transcription Factor Associations 2026 1.0 null SCRT2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.1207 PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_2_CTCF Rummagene Transcription Factor Associations 2026 1.0 null periventricular stratum of PPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20191 superficial stratum of THyB-P Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1344 H3K27ac_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null UACC62 CCLE Cell Line Gene CNV Profiles 1.0 1.37775 NCIH2170 CCLE Cell Line Gene CNV Profiles -1.0 -1.53767 H3K27me3_megakaryocyte_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1395 COSMIC Cell Line Gene CNV Profiles 1.0 2.64759 intermediate portion of DFC (area 9/46) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.39754 GSE233183,GSE233187_2_v_9_larp1_human RummaGEO Gene Perturbation Signatures 1.0 null Retrosplenial area, lateral agranular part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16877 Entorhinal area, medial part, dorsal zone, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32053 GSU CCLE Cell Line Gene CNV Profiles 1.0 1.54212 KLC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73086 PC3 CCLE Cell Line Gene CNV Profiles -1.0 -1.6373 INPP5F CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93482 paracentral lobule, anterior part, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.94179 hsa-miR-4477b TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 sublayer 6b of PCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26691 hsa-miR-3124-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 CBP-20019798-JUKART-HUMAN ChEA Transcription Factor Targets 2022 1.0 null CTCF_G1E-ER4_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MNX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72399 frontal pole, right, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.11857 NCIH1755 CCLE Cell Line Gene CNV Profiles -1.0 -1.5093 Male-pattern baldness GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.85229 HOXD12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25644 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7048-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Uterine Carcinosarcoma_UCS_TCGA-N5-A4RM-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TOMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55319 layer II of rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.34115 H3K9ac_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PLAG1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 94.5556 127399 DepMap CRISPR Gene Dependency 1.0 2.83539 BFTC-905 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.27639 GSE242521,GSE242522_0_v_1_mettl3_human RummaGEO Gene Perturbation Signatures 1.0 null Postpiriform transition area, layers 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43202 CBX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55518 SNU-387 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.984459 Basomedial amygdalar nucleus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32741 NCI-H1882 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09911 SARC9371 COSMIC Cell Line Gene Mutation Profiles 1.0 null MDA-MB-231 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.54461 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4642-01B-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH1105 CCLE Cell Line Gene CNV Profiles 1.0 1.84944 POLR2AphosphoS5_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNX11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76945 FOS JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.3945 COL26A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51903 Pineoblastoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.269 EZH2 ENCODE Transcription Factor Targets 1.0 null cingulate gyrus, frontal part, left, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.827733 CENPX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29852 mantle zone of r10Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.81995 central nucleus of inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.95337 GOLGA8B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80561 hsa-miR-198 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 SPIRE2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38714 MYC ENCODE Transcription Factor Targets 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-A4MY-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.02828 GSE151612_4_v_7_pracinostat_human RummaGEO Drug Perturbation Signatures 1.0 null hsa-miR-331-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 H3K9me3_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null RPMI 8226 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08735 mantle zone of r9Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.61046 SIRT4_KO_GDS4823_505_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null OB glomerular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15734 Stomach Smooth Muscle Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 1.85531 HEC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null central gray of the pons, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.960051 Brain Lower Grade Glioma_LGG_TCGA-RY-A83X-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-NJ-A55R-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null red nucleus, magnocellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26286 retropontine reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24031 superficial stratum of PPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43129 dentate gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.01913 496100523_HIP_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.36056 STOX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60371 posterior intralaminar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.5472 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EJ-01A-11R-A155-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4775 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 hsa-let-7a TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 Mediodorsal nucleus of the thalamus, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.94271 SIRT4_KO_GSE56321_391_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GSE173169,GSE173170_0_v_1_epc2_human RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null USF1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Anteromedial visual area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.49773 superficial stratum of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.63824 COA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.10489 hsa-miR-3685 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 ITFG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46308 Cardiac muscle TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 substantia nigra, pars compacta, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.869606 stratum pyramidale of rostral CA2 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.98969 amygdalo-striatal transition Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21443 transverse gyri, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.93421 NH12 DepMap CRISPR Gene Dependency 1.0 3.5679 CDK8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56723 P32-ISH COSMIC Cell Line Gene Mutation Profiles 1.0 null NCI-H2170 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.54461 PHC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51546 MINO CCLE Cell Line Gene CNV Profiles -1.0 -2.13125 mRNA_SOX2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null NFIC::TLX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.0 r3 pontine raphe nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02674 SMIM30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71257 Entorhinal area, medial part, ventral zone, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.023 RERF-GC-1B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18543 Prostate adenocarcinoma_PRAD_TCGA-HC-8265-01A-11R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MYLK_knockdown_48_GSE14525 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.79435 Liver hepatocellular carcinoma_LIHC_TCGA-5C-A9VG-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sarcoma_SARC_TCGA-DX-A6YR-01A-33R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7418-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null THRB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71734 OVCA 432 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08735 ZNF575 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29915 layer 3 of AOV cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.67691 UMUC3 DepMap CRISPR Gene Dependency 1.0 2.84525 ZNF136 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.9653 EJM CCLE Cell Line Gene CNV Profiles 1.0 1.48935 HCC2270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.44333 hsa-miR-196a TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 EFE184 DepMap CRISPR Gene Dependency 1.0 2.60444 superficial stratum of r9BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.20653 medial subdivision of area 10 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.845309 Nucleus prepositus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.64935 SW684 COSMIC Cell Line Gene Mutation Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9R7-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-let-7g TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 PIWIL4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29146 Skin disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.862 superficial stratum of LAP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40843 Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3BM-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Paraventricular hypothalamic nucleus, parvicellular division, medial parvicellular part, dorsal zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03111 r8 part of the paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10202 PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_2_CTCF Rummagene Transcription Factor Associations 2026 1.0 null intercalated nucleus of medulla Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.27373 PRKDC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54676 H3K9me3_erythroblast_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null periaqueductal gray substance, dorsolateral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.61547 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SS-01A-12R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FKBP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59126 NCI-H1435 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18976 Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78N-01A-12R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inner SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.825305 r7 (gustatory) part of solitary complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13791 ZNF320 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 196.718 SUZ12-20075857-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null SLC11A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49003 r6 (gustatory) part of solitary complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.28044 hsa-miR-4782-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 SIRT4_KO_GDS4823_30_mouse_hepatocytes GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A13J-01A-11R-A10U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MYBL2-22936984-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GSE154350_1_v_0_ascl2_human RummaGEO Gene Perturbation Signatures 1.0 null CTCF_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PTK7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95954 NO11 DepMap CRISPR Gene Dependency 1.0 5.47828 dorsal entopeduncular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42968 PANC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.32737 intermediate stratum of r10Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.1708 H3K9me3_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null EBC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.992974 intermediate stratum of r5BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.40776 H3K9me3_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ANXA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05329 BEN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 3.19301 REST JASPAR Predicted Human Transcription Factor Targets 2025 1.0 51.0914 BIRC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73755 SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null intermediate stratum of r6BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0068 SIDT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25938 SLC25A45 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92729 Anterior olfactory nucleus, posteroventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42175 H3K4me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-O2-A52S-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null FAM161A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29615 496100450_HIP_no dementia_no TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.56873 PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S8-DUX4_SpecDMCs-Unnamed_3_DUX4 Rummagene Transcription Factor Associations 2026 1.0 null MEPCE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44463 CHID1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55783 MYC_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null r6 part of basomedial reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.60664 mantle zone of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.98627 fastigial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.51813 hsa-miR-219-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 FOXL1 JASPAR Predicted Transcription Factor Targets 1.0 null supragenual nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.12487 KNS62 DepMap CRISPR Gene Dependency 1.0 2.25341 NCIH2342 CCLE Cell Line Gene CNV Profiles 1.0 1.54972 SDF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81457 Basolateral amygdalar nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01204 NCI-H720 COSMIC Cell Line Gene Mutation Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5888-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null upper dorsal lateral hypothalamic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21717 outer CP in posterosuperior (dorsal) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.61742 SPTY2D1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78526 GSE216274,GSE216292_4_v_2_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null H3K9me3_CH12.LX_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-4306 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 MYPOP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69663 medial habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.52663 PPM1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21869 Crus I, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.827926 HT-115 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.833545 ZBTB26 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.161 Sarcoma_SARC_TCGA-DX-A3UC-01A-11R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SUZ12 ChEA Transcription Factor Targets 1.0 null BIN67 DepMap CRISPR Gene Dependency 1.0 9.06717 ZNF619 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05471 ZNF12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18285 caudal (posterior) extramural migratory stream Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.879853 496100622_HIP_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.05507 planum polare, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.878335 APLN_KO_GDS3228_601_mouse_Heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GSE193541_1_v_3_nifurtimox_human RummaGEO Drug Perturbation Signatures 1.0 null 496100394_TCx_probable Alzheimer's disease_no TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.17447 Brain Lower Grade Glioma_LGG_TCGA-S9-A7QY-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC2218 CCLE Cell Line Gene CNV Profiles -1.0 -3.21049 ASPM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53386 Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7591-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-874 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 dorsal juxtacommissural pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01836 BTG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54781 PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_2_CTCF Rummagene Transcription Factor Associations 2026 1.0 null EEF1G CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -7.82121 Anterior cingulate area, ventral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.54347 CREB3L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20657 ZFP14 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 73.0183 dentate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.956055 APOBEC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28111 CX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.47761 m2 part of pararubral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12149 Nucleus accumbens Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37256 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-RA-A741-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU-668 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.27639 HCC1599 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.55732 paraventricular nucleus of hypothalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.34721 medial subdivision of central nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.11451 Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null sublayer 6b of OCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14261 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70N-01A-12R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null embryonic stem feeder layer BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.959223 Disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.984 NFYA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.7281 Bladder Urothelial Carcinoma_BLCA_TCGA-S5-A6DX-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BICR10 DepMap CRISPR Gene Dependency 1.0 4.55793 SEPTIN7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22873 H3K4me3_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Substantia innominata Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08298 NCI-H510A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.54461 USF1 ENCODE Transcription Factor Targets 1.0 null adiposetissue BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.07481 Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GX-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null temporal pole, left, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.02805 lateral hypothalamic area, anterior part Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.992963 HCC1359 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.873184 H3K27me3_megakaryocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RPL22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92319 anterior paraventricular nucleus of thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28427 AEN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49807 lower limb region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.11679 NIHOVCAR3 CCLE Cell Line Gene CNV Profiles 1.0 1.95963 HUG1N CCLE Cell Line Gene CNV Profiles 1.0 1.84365 PAM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.23902 PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_3_CTCF Rummagene Transcription Factor Associations 2026 1.0 null ZNF716 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.12536 GTF2F1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2033 intermediate stratum of isBI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48061 Retrosplenial area, ventral part, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24358 layer V of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.919429 KARPAS299 DepMap CRISPR Gene Dependency 1.0 3.52588 MICALL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2718 TMEM41A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99052 posterior orbital gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.68944 r6 part of nucleus prepositus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.57256 periventricular stratum of RtC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00809 HCFC1_ES-E14_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null icSARA deltaORF6_36Hour_23365422_GSE33267 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.78063 BACH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6649 SMC3_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Orbital area, ventrolateral part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -4.03412 hsa-miR-4500 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 rostral paraventricular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34429 m2 part of paranigral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09702 MCC26 COSMIC Cell Line Gene Mutation Profiles 1.0 null MOV10L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36432 hsa-miR-4495 TargetScan Predicted Conserved microRNA Targets 1.0 1.45615 HAND2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.6795 SP in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.888068 Crus 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11842 CA3 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.99701 EJM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.868479 Brain Lower Grade Glioma_LGG_TCGA-CS-5393-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF606 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19304 Brain Lower Grade Glioma_LGG_TCGA-FG-8187-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SERPINF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.33778 FUCA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75458 HDAC2_Deficiency_GDS2624_658_mouse_Embryonic heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null SNAI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.0145 DAN-G Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.868479 LIMD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63797 Stomach TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 hsa-miR-4644 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 GDPD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.66328 HIKESHI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24025 periventricular stratum of r6BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.57256 r9 part of paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.20653 pancreas BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.925475 inner CP in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.18703 HCC4011 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08735 A549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.64657 Lung adenocarcinoma_LUAD_TCGA-64-1679-01A-21R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of r9Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23374 59M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01998 Paraventricular nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23003 ZNF75D JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.2655 BMAL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29187 TFAP2E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6281 Pyramus (VIII), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08717 layer 2 of ERCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28064 r10 part of spinal trigeminal nucleus, caudal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05775 Brain Lower Grade Glioma_LGG_TCGA-HT-7854-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4516 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 hsa-miR-924 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 H3K9me3_erythroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SP in entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.07499 CTCF_CH12.LX_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE192362_1_v_0_erastin_human RummaGEO Drug Perturbation Signatures 1.0 null Duodenum Mucosa Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -0.89164 Sarcoma_SARC_TCGA-QQ-A5V2-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Hypotrichosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.085 layer 3 of ERCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06909 Crus 1, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08898 EMX2_Deficiency_GDS3173_607_mouse_Embryonic urogenital epithelium - day 10.5 GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null SIHA CCLE Cell Line Gene CNV Profiles 1.0 1.64171 membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null hsa-miR-625 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 periventricular stratum of r6Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27909 Mesothelioma_MESO_TCGA-SC-A6LM-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU626 CCLE Cell Line Gene CNV Profiles -1.0 -1.63986 Brain Lower Grade Glioma_LGG_TCGA-DU-5870-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-G9-6365-11A-01R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SIX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35075 H3K9me3_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7XP-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CAL-78 COSMIC Cell Line Gene Mutation Profiles 1.0 null hsa-miR-3617 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 hsa-miR-3665 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 mantle zone of r5BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.45068 VZ in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.1613 hsa-miR-3924 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 CTCF_G1E-ER4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null IV, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.4998 OB olfactory fiber layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.6388 periventricular stratum of r5BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.64935 mantle zone of ERCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40762 NCI-H1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.37185 BICR 78 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.94758 Adrenocortical carcinoma_ACC_TCGA-PK-A5HB-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Entorhinal area, lateral part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.8751 rostral interpeduncular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03053 MRPL17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6672 PGM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84771 external part of AOV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.51902 TFDP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17772 hsa-miR-98 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 layer II of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.62014 SNU387 DepMap CRISPR Gene Dependency 1.0 4.04519 CXADR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77458 ELF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.5632 Prostate adenocarcinoma_PRAD_TCGA-HC-7738-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RJ-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H1437 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.089 496100328_TCx_possible Alzheimer's disease_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.19789 BRD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55349 A549 CCLE Cell Line Gene CNV Profiles -1.0 -1.45449 embryonic stem no feeder BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.07371 Sarcoma_SARC_TCGA-HB-A3L4-01A-11R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-586 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 KDM4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8164 GR-ST COSMIC Cell Line Gene Mutation Profiles 1.0 null intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null subgenual (subcallosal) division of MFC (area 25) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.24655 lateral intermediate part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 3.34509 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70Q-01A-13R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1M6-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PIGA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78843 lateral medullary reticular group, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.05124 intercalate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10884 NFIB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.2126 r9 part of spinal vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.04212 parvicellular (lateral) subparafascicular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12034 KU812 DepMap CRISPR Gene Dependency 1.0 4.42723 layer VI of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.30175 RPS6KA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98569 COLO-792 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K27me3_liver_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ARL6IP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6275 Crus 1, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.54868 IKBKB_Constitutional activation_GDS4119_621_mouse_Prostate epithelium GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null H3K27me3_erythroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE191015_1_v_3_gsdmb_human RummaGEO Gene Perturbation Signatures -1.0 null 496100367_FWM_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.01587 posterior (ventral) nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38007 medial portion of STH Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.827344 H3K9me3_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MOLT-16 COSMIC Cell Line Gene Mutation Profiles 1.0 null anteroventral nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.21679 hsa-miR-185 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 paracentral lobule, posterior part, left, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.89497 GSE140997_4_v_3_nsun6_human RummaGEO Gene Perturbation Signatures -1.0 null FOXN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89058 C1orf116 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82576 heart muscle HPA Tissue Protein Expression Profiles 1.0 1.18259 IV, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.04346 KU812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09776 HCFC1 ENCODE Transcription Factor Targets 1.0 null Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part, lateral zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17534 superficial stratum of r8Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25757 pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null HT-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null Basolateral amygdalar nucleus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09702 YAE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.5319 PCGF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.79321 CEBPB-20176806-THIOMACROPHAGE-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null H3K4me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null RCH-ACV COSMIC Cell Line Gene Mutation Profiles 1.0 null pontine raphe nucleus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.61798 layer III of piriform cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.86732 H3K9me3_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CADO-ES1 COSMIC Cell Line Gene Mutation Profiles 1.0 null hsa-miR-4738-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7593-01A-11R-2232-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null occipital pole, left, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.1497 ZNF257 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 65.4512 submedius thalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26745 JHH-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.984459 hsa-let-7e TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 Basomedial amygdalar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19774 medial preoptic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.879207 midline nuclear complex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.961904 ASPC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.873184 H3K9me3_fibroblast of lung_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null BICR16 CCLE Cell Line Gene CNV Profiles 1.0 1.32888 nucleus LOCATE Predicted Protein Localization Annotations 1.0 null WT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2081 NCI-H847 COSMIC Cell Line Gene Mutation Profiles 1.0 null hsa-let-7c TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 H3K9me3_erythroblast_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null superficial stratum of r5Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12542 SCC-15 COSMIC Cell Line Gene Mutation Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7PW-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EW7 DepMap CRISPR Gene Dependency 1.0 2.09393 Gastrointestinal tract TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5560-01A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100532_FWM_no dementia_no TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.52363 SMC3 ENCODE Transcription Factor Targets 1.0 null HS 766T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09911 Sarcoma_SARC_TCGA-DX-A1KY-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SIRT4_KO_GDS4823_22_mouse_Liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GABPA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.7407 H3K9ac_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Vertebrate muscular system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 NEURL1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66833 MFE-280 COSMIC Cell Line Gene CNV Profiles 1.0 2.64759 H3K27me3_Penis Foreskin Fibroblast Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K9me3_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-4723-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 Entorhinal area, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.70211 Pyramus (VIII) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.037 superficial stratum of OB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29776 gyrus rectus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.887506 cell part LOCATE Predicted Protein Localization Annotations 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-63-A5ML-01A-31R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Alopecia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.096 Paraflocculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.6487 inner CP in primary auditory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.824723 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73F-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KLF10 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 103.401 Brain Lower Grade Glioma_LGG_TCGA-S9-A7IZ-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sarcoma_SARC_TCGA-K1-A42X-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null outer CP in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.19689 HES1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.9134 DUSP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78949 hsa-miR-369-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 H3K27me3_cardiac mesoderm_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null r10 part of dorsal parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29559 IM9 DepMap CRISPR Gene Dependency 1.0 2.77084 EFR3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93849 cochlear nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.17556 CPC-N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14426 emboliform nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.24423 hsa-miR-18a TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 A388 DepMap CRISPR Gene Dependency 1.0 2.56486 DETROIT 562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.868479 hsa-miR-4300 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 VMCUB1 CCLE Cell Line Gene CNV Profiles 1.0 1.37567 PCYT1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25427 TGIF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.4944 ELK4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.4158 PMM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31839 Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-F2-A44G-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cuneiform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.24829 MZ7-MEL COSMIC Cell Line Gene Mutation Profiles 1.0 null ZC3H12B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1726 hsa-miR-4735-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6942-01A-21R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_erythroblast_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null SOD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.74504 periventricular stratum of r8Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03097 basointermediate isthmic reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47889 hsa-miR-592 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 periventricular stratum of AStr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21514 CALU-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.089 Liver hepatocellular carcinoma_LIHC_TCGA-ZS-A9CF-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SETD1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16359 MAP3K4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49255 central amygdaloid nucleus, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.70121 Cardiovascular system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 HCC4017 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.089 GSE225982_1_v_0_ezetimibe_human RummaGEO Drug Perturbation Signatures -1.0 null GOLGA7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67032 SW948 DepMap CRISPR Gene Dependency 1.0 2.42532 Brain Lower Grade Glioma_LGG_TCGA-S9-A7QX-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RAD21 ENCODE Transcription Factor Targets 1.0 null SF268 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09776 inferior olivary complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.54498 r9 part of the vestibular column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.61235 SU-DHL-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.950064 METTL8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41421 TMEM54 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7054 MATK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77796 r10 part of the vestibular column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.82233 NCI-H1770 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09911 URGCP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5021 layer IIIa of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.6074 NCI-H716 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.44492 TMEM51 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02219 layer 1 of PCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25234 r9 part of the trigeminal column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23374 UQCC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49338 FASTKD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60978 sublayer 6a of OCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16997 lateral subdivision of BNST Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.02296 trachea BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.814 KYSE-180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.46054 ZNF530 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 79.9769 PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_2_JUN Rummagene Transcription Factor Associations 2026 1.0 null NOTCH1_Deficiency_GDS2848_635_mouse_Hair follicles GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null paraventricular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.967732 BOLA2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93282 CTCF_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RREB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 119.455 CPSF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56669 GSE226355,GSE226357_1_v_0_ybx1_human RummaGEO Gene Perturbation Signatures -1.0 null layer II of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.854642 NUGC-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.984459 Postpiriform transition area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05826 ML1 CCLE Cell Line Gene CNV Profiles -1.0 -1.99974 Liver hepatocellular carcinoma_LIHC_TCGA-EP-A2KA-01A-11R-A180-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H1792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.905248 BLUE1 DepMap CRISPR Gene Dependency 1.0 2.01219 inner CP in midcingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.980267 ZNF669 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.5 496100391_FWM_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.20091 NAB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05664 GNB4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71648 H3K4me1_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Pineal gland cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.236 ZNF672 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20252 AGXT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47511 CLBA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87709 HSFX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88967 SP in ventromedial extrastriate cortex (VP) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.996809 LXF-289 COSMIC Cell Line Gene Mutation Profiles 1.0 null USP49 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24793 BEN CCLE Cell Line Gene CNV Profiles 1.0 3.2803 ZNF398 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13524 H2AC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.77508 CA2 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.36097 hsa-miR-4791 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 USP39 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44717 intermediate stratum of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.34881 Bed nuclei of the stria terminalis, anterior division, rhomboid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -3.01659 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MV-06A-11R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TM-A7CF-02A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ARL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55874 lateral reticular nucleus (principal part) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.874891 Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GY-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SVBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72303 Crus 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32741 Androgenic alopecia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.599 ZNF783 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46874 superficial stratum of r8BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10138 HARA DepMap CRISPR Gene Dependency 1.0 2.35862 RPL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26927 cingulum bundle, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.78077 Acute Myeloid Leukemia_LAML_TCGA-AB-2849-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KHM-1B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.873184 PECAPJ41CLONED2 DepMap CRISPR Gene Dependency 1.0 2.27921 layer 4 of FCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00473 oocyte BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.46784 mantle zone of r8Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15556 NCI-H2198 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.71772 TBX2-33478486-IMR90-HUMAN-LUNG ChEA Transcription Factor Targets 2022 1.0 null Muscle TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 r10 part of the inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.86599 NCI-H727 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.37185 interstitial nucleus of the posterior limb of the anterior commissure Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.82343 III, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.65394 U-698-M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.948749 Androgenic alopecia DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.984 MYOG_myocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Esophagus - Gastroesophageal Junction GTEx Tissue Gene Expression Profiles 2023 1.0 7.2024 superficial stratum of ERCx (cortical plate/marginal zone) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40922 NCI-H1693 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.984459 paraventricular nucleus, peduncular or principal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20191 Hypotrichosis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.984 ZNF789 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91925 496100466_PCx_probable Alzheimer's disease_no TBI_89_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.06483 Ventral posterior complex of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0546 outer SZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.07837 BEN COSMIC Cell Line Gene CNV Profiles 1.0 2.64759 OUMS-23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.20045 PANC 03.27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.0977 Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78O-01A-12R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null medial part of r10B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.98265 Lung squamous cell carcinoma_LUSC_TCGA-33-4587-01A-11R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SLC39A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34239 midbrain raphe nuclei Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.29908 U-937 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18543 Edinger-Westphal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.852098 superficial stratum of POH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13313 496100292_PCx_no dementia_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.15757 NB13 DepMap CRISPR Gene Dependency 1.0 6.02557 paraventricular nucleus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25502 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-11A-13R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EHF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.7625 KASUMI1 DepMap CRISPR Gene Dependency 1.0 2.17803 ADM5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18578 NB17 DepMap CRISPR Gene Dependency 1.0 7.65997 HCC2218 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15734 intermediate stratum of r9Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.03942 ACTR6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27473 MYBL2 ChEA Transcription Factor Targets 1.0 null SEMA6B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46393 ZNF331 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.5898 Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HL-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EW22 DepMap CRISPR Gene Dependency 1.0 5.04216 inferior occipital gyrus, left, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.855678 r8 part of spinal trigeminal nucleus, interpolar part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26157 paraventricular nucleus, cap part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44533 r10 part of spinal vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.16794 IZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.84183 H3K27me3_erythroblast_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null inferior temporal gyrus, left, bank of the its Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.899634 nucleus of the inferior collicular brachium, caudal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.29275 TRPC4AP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2479 SIHA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03756 Acute Myeloid Leukemia_LAML_TCGA-AB-2933-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TCEAL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71737 Parapyramidal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07193 HCC1187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.984459 REH COSMIC Cell Line Gene Mutation Profiles 1.0 null ZNF816 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 69.9449 MYLA DepMap CRISPR Gene Dependency 1.0 2.2717 r8 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00162 dorsal raphe nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.906711 Anterior cingulate area, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07213 CHAGO-K-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.0389 hsa-miR-1284 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 Keloid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.249 hsa-miR-4803 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 FAM50B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73755 subthalamic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.829698 superficial stratum of r5BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48388 icSARS CoV_60Hour_23365422_GSE33267 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.41137 MALSU1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77489 REEP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.93881 RELA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.2778 POLR2A_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Nucleus of the posterior commissure Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44248 ZSCAN16 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.1641 THUMPD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.15321 496100484_FWM_no dementia_no TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.73951 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7X3-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-660 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 entorhinal cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40762 H3K9me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null RNASET2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35287 GSE240439_1_v_2_decitabine_human RummaGEO Drug Perturbation Signatures 1.0 null TCFL5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68842 periventricular stratum of r7Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14143 MDA-MB-436 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.984459 496100315_TCx_no dementia_TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.1974 morphine_mus musculus_gpl6246_gse17731 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Alopecia DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.984 hsa-miR-18b TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 Paraflocculus, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40433 abducens motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.64935 Heart TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 hsa-miR-2054 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 dorsal paracommissural tectal nucleus, m1 part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10831 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70X-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE193541_0_v_3_nifurtimox_human RummaGEO Drug Perturbation Signatures 1.0 null ZNF692 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 59.6671 NCI-H2052 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.64657 NASP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28812 NCIH69 CCLE Cell Line Gene CNV Profiles -1.0 -1.64499 PRRX2 JASPAR Predicted Transcription Factor Targets 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4224-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r10 part of gigantocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.82947 subethmoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11569 Pancreatic adenocarcinoma_PAAD_TCGA-HV-A5A3-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-WY-A85B-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GCM1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.2947 GSE224131_2_v_1_mafb_human RummaGEO Gene Perturbation Signatures 1.0 null CTCF_MEL cell line_mm9_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null Temporal association areas, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07935 Acute Myeloid Leukemia_LAML_TCGA-AB-2807-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Mesothelioma_MESO_TCGA-SC-A6LN-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COLO320 CCLE Cell Line Gene CNV Profiles 1.0 1.45689 MCC13 COSMIC Cell Line Gene Mutation Profiles 1.0 null EPHA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65462 RARA::RXRG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.7984 IRF4-20064451-CD4+T-MOUSE ChEA Transcription Factor Targets 2022 1.0 null paraventricular nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.37363 Posterior complex of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.96088 RXRG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.278 Alimentary canal TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 GSE186647,GSE217288_2_v_4_hnrnpc_human RummaGEO Gene Perturbation Signatures -1.0 null DDX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52068 MDAMB436 CCLE Cell Line Gene CNV Profiles -1.0 -2.0158 SP in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.88389 PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_2_CTCF Rummagene Transcription Factor Associations 2026 1.0 null DUSP28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.48641 NR3C1 JASPAR Predicted Transcription Factor Targets 1.0 null abducens nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.11143 Prostate adenocarcinoma_PRAD_TCGA-EJ-7788-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null central medullary reticular group, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.32661 MFE319 DepMap CRISPR Gene Dependency 1.0 3.92322 icSARA deltaORF6_48Hour_23365422_GSE33267 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.18813 NCI-H2196 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.31612 medial part of the lateral habenular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0435 DB CCLE Cell Line Gene CNV Profiles -1.0 -1.96255 ZNF662 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.74621 LHX8_Deficiency_GDS3254_600_mouse_Newborn ovaries GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null ETV2::FIGLA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.6867 Skeletal Muscle Male Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.03668 GSE128730_4_v_5_neratinib_human RummaGEO Drug Perturbation Signatures 1.0 null lateral hypothalamic area, anterior region, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.29649 SNAPC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55154 H4C3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27793 RNF208 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76581 Integumentary system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.984 496100515_HIP_dementia_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.20885 TADA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69777 DENR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43861 HGC27 CCLE Cell Line Gene CNV Profiles -1.0 -1.7638 medial orbital gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.922573 Orbital area, medial part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01262 hsa-let-7b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 medial part of MPO Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29469 SLFN12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16626 H3K9me3_Brain Inferior Temporal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null r9 part of the inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.49298 Acute Myeloid Leukemia_LAML_TCGA-AB-2966-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH650 DepMap CRISPR Gene Dependency 1.0 2.30258 H3K4me3_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TCIRG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60988 Anterior cingulate area, ventral part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03994 Viscus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 blastocysts BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.23083 LS-123 COSMIC Cell Line Gene Mutation Profiles 1.0 null hsa-miR-4735-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 BCL2L10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84519 gracile nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.41813 Hair disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.045 vestibular nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.86924