association dataset threshold value standardized value GSE110178_1_v_0_tranylcypromine_mouse RummaGEO Drug Perturbation Signatures 1.0 null Rhinitis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.674 DA-35-DU85_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.558964 GSE195559_8_v_4_notch1_human RummaGEO Gene Perturbation Signatures 1.0 null GSE77108_6_v_2_saha_human RummaGEO Drug Perturbation Signatures -1.0 null t60-adrenal_consensus MoTrPAC Rat Endurance Exercise Training 1.0 5.54768 Epithalamus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.029 Lymphatic system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.043 Sclerosing cholangitis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.592 BB-20-UU03_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.275552 Pancreas GTEx Tissue Gene Expression Profiles 2023 -1.0 -0.676759 JD-44-KF86_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.487954 Corpus striatum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.002 GSE152441,GSE152442_1_v_3_folic acid_human RummaGEO Drug Perturbation Signatures 1.0 null NMUR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.88834 Brain - Cerebellum GTEx Tissue Gene Expression Profiles 2023 -1.0 -1.06267 GSE206516,GSE206518_3_v_4_ptdss2_human RummaGEO Gene Perturbation Signatures -1.0 null KA-81-AG66_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.323184 GSE151612_0_v_7_pracinostat_human RummaGEO Drug Perturbation Signatures 1.0 null GSE180377_2_v_1_lipa_mouse RummaGEO Gene Perturbation Signatures 1.0 null KA-75-LP02_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.231339 GSE129293_0_v_1_chd4_human RummaGEO Gene Perturbation Signatures 1.0 null GSE208171_0_v_1_zc4h2_human RummaGEO Gene Perturbation Signatures -1.0 null GSE135030_8_v_1_fludarabine_human RummaGEO Drug Perturbation Signatures -1.0 null GSE171292_5_v_2_ehhadh_mouse RummaGEO Gene Perturbation Signatures 1.0 null APEH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.41587 GSE152937_6_v_5_slc16a13_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-Kasumi-1-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_Kasumi-1_LYL1 Rummagene Transcription Factor Associations 2026 1.0 null IRF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.04533 GSE162276_2_v_0_pparg_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE237040_6_v_1_notch3_mouse RummaGEO Gene Perturbation Signatures -1.0 null CE-15-YU05_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.256917 GSE178560_0_v_1_irf7_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE133683_1_v_0_doxorubicin_mouse RummaGEO Drug Perturbation Signatures 1.0 null Metabolism Reactome Pathways 2024 1.0 null GSE131649_2_v_8_hemin_human RummaGEO Drug Perturbation Signatures -1.0 null Allergic disease (asthma, hay fever or eczema) GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.752288 GSE135514_2_v_0_dasatinib_human RummaGEO Drug Perturbation Signatures -1.0 null PAX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.9278 GSE148695,GSE167284_2_v_1_satb2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GA-28-SS67_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.536637 ZIC5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 112.124 PMC8253095-MOL2-15-1942-s005.xlsx-gene_lists-Genes_associated_with_H3K27ac-positive_sample_selective_AR_sites_AR Rummagene Transcription Factor Associations 2026 1.0 null FD-91-OK66_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.74855 IFI27L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55116 496100532_FWM_no dementia_no TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.00423 GSE195559_2_v_4_notch1_human RummaGEO Gene Perturbation Signatures 1.0 null GSE261563_0_v_1_atrx_human RummaGEO Gene Perturbation Signatures 1.0 null NASP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.101 PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-3_MYB Rummagene Transcription Factor Associations 2026 1.0 null GSE172020_0_v_3_testosterone_mouse RummaGEO Drug Perturbation Signatures 1.0 null Cholinergic synapse COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.685 GSE213588_9_v_3_trametinib_human RummaGEO Drug Perturbation Signatures 1.0 null Ganglion TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.297 496100367_FWM_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.94861 PMC12518476-10067_2025_7574_MOESM8_ESM.xlsx-Sheet1-Down_regulated_DEGs_of_KD_AR Rummagene Transcription Factor Associations 2026 1.0 null GSE132948,GSE132949_0_v_3_msi2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Multiple sclerosis GWAS Catalog SNP-Phenotype Associations 2025 1.0 3.5699 FF-28-ES17_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.55118 GSE237040_4_v_1_notch3_mouse RummaGEO Gene Perturbation Signatures -1.0 null Leukemia cell TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 ZNF148 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 145.359 GSE227592_13_v_1_adar_human RummaGEO Gene Perturbation Signatures 1.0 null Immune system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 496100616_FWM_no dementia_TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.85809 GSE167956_4_v_0_trim28_human RummaGEO Gene Perturbation Signatures 1.0 null BC-25-VR48_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.348215 PSMD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45586 Gfi1b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 27.3549 NHLH1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.7143 PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Ensembl_ID_AR Rummagene Transcription Factor Associations 2026 1.0 null GSE160001,GSE160670_0_v_2_lapatinib_human RummaGEO Drug Perturbation Signatures -1.0 null BIRC6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.33836 BE-79-QU25_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.86115 GSE205316,GSE205317_2_v_3_nrip1_mouse RummaGEO Gene Perturbation Signatures 1.0 null KB-92-MK13_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.216778 CT-26 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.994 GSE229973_3_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null CEP55 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.54571 GSE171177,GSE171181_1_v_0_e7107_human RummaGEO Drug Perturbation Signatures -1.0 null GSE114284_4_v_5_irf1_human RummaGEO Gene Perturbation Signatures 1.0 null DC-70-EK34_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.200553 GSE247764_0_v_2_nell2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE125007,GSE125008_6_v_0_uhrf1_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC11067031-pnas.2317690121.sd06.xlsx-gene_list_14_txt-Differentially_expressed_genes_between_PML_RARA_GFP_vs_C88A_PML_RARA_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA Rummagene Transcription Factor Associations 2026 1.0 null GSE198826,GSE198911_1_v_2_dexamethasone_mouse RummaGEO Drug Perturbation Signatures -1.0 null NE-94-VE83_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.2232 GSE203308_1_v_3_brf1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE216147_2_v_1_rbm20_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE148066,GSE157787_8_v_7_n4bp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.923 PMC11519602-41418_2024_1333_MOESM3_ESM.pdf-26-NFKB1_NFKB1 Rummagene Transcription Factor Associations 2026 1.0 null CTSK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.03232 GSE131649_4_v_9_hemin_human RummaGEO Drug Perturbation Signatures -1.0 null RTN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.08832 Upper respiratory tract disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.674 GSE218580_1_v_5_fentanyl_mouse RummaGEO Drug Perturbation Signatures 1.0 null Esophagus - Mucosa GTEx Tissue Gene Expression Profiles 2023 1.0 1.41921 Ulcerative colitis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.923 Pontocerebellar hypoplasia type 6 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.32 Nasal cavity disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.674 Testis GTEx Tissue Gene Expression Profiles 2023 -1.0 -0.877611 HES1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.8824 ZNF701 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 79.5282 LE-50-AP60_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.221095 Erythroid cell TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.043 NHLH2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 88.6071 PMC11551338-pnas.2411189121.sd01.xlsx-PXR-Unnamed_0_NR1I2 Rummagene Transcription Factor Associations 2026 1.0 null GSE242199_6_v_5_ntrk2_human RummaGEO Gene Perturbation Signatures -1.0 null Cingulate cortex TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.138 Eicosanoid metabolism via cyclooxygenases COX WikiPathways Pathways 2024 1.0 null GSE150072,GSE169209_6_v_9_qser1_human RummaGEO Gene Perturbation Signatures -1.0 null PHB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44215 GSE168596_2_v_3_adiponectin_mouse RummaGEO Drug Perturbation Signatures 1.0 null E2F8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.1527 Autoimmune disease of musculoskeletal system DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.902 GSE201309_1_v_0_matrine_human RummaGEO Drug Perturbation Signatures -1.0 null H1-7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4278 LAGE3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.13608 Bone inflammation disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.902 ZBED1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.24301 Tongue epithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.781 ZC3H10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.76665 t60-adrenal_male_1w MoTrPAC Rat Endurance Exercise Training 1.0 2.24956 GSE111385_2_v_1_tgfbr2_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT38_Protein_cis-instrument_MR-eTable_38_Cis-instrument_Mendelian_randomizaion_screen_of_1_901_cortical_proteins_on_lifetime_smoking_behavior_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null GSE216043_10_v_4_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null ZNF740 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 155.047 GSE229468,GSE229471_2_v_1_znf587_human RummaGEO Gene Perturbation Signatures 1.0 null GSE196117_6_v_7_clarithromycin_human RummaGEO Drug Perturbation Signatures -1.0 null BD-11-DV28_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.79698 GSE137818_5_v_1_brca2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE219195_1_v_2_rbm12_human RummaGEO Gene Perturbation Signatures 1.0 null Natural killer cell_Spleen_Mouse CellMarker Gene-Cell Type Associations 1.0 null GSE157282_0_v_1_doxorubicin_human RummaGEO Drug Perturbation Signatures -1.0 null GSE147613_1_v_0_cisplatin_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE202434,GSE202438_3_v_14_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null WM793_SKIN CCLE Cell Line Proteomics 1.0 10.7463 GSE247764_4_v_2_nell2_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC6484770-41388_2018_602_MOESM5_ESM.xlsx-up_P53_vs_con-Unnamed_1_TP53 Rummagene Transcription Factor Associations 2026 1.0 null Vaginal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.146 PRDM4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.20996 EA-18-FP00_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.48929 TF-77-DW08_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.545597 PSME2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.07722 Uterine lavage TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.71 DD-74-PJ26_0.01uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.244545 ZNF707 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 66.2844 GSE206516,GSE206518_0_v_4_ptdss2_human RummaGEO Gene Perturbation Signatures -1.0 null GSE242199_6_v_7_ntrk2_human RummaGEO Gene Perturbation Signatures -1.0 null GSE213588_8_v_12_trametinib_human RummaGEO Drug Perturbation Signatures -1.0 null PDGFA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02356 GSE242083,GSE242098_2_v_1_med1_human RummaGEO Gene Perturbation Signatures 1.0 null Autoimmune disease of endocrine system DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.339 ZNF449 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.8238 GSE95688_7_v_5_glutathione_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE87412,GSE92423_0_v_1_dnmt3a_mouse RummaGEO Gene Perturbation Signatures 1.0 null GA-88-CF36_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.39619 GSE217776,GSE217829_2_v_6_sgf29_human RummaGEO Gene Perturbation Signatures -1.0 null GSE213219_0_v_1_st3gal3_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE172020_0_v_2_testosterone_mouse RummaGEO Drug Perturbation Signatures 1.0 null CC-17-JL38_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.12599 AC-30-XU83_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.740735 GSE143212_1_v_2_bleomycin_mouse RummaGEO Drug Perturbation Signatures 1.0 null PMC8185471-mmc4.xlsx-D2-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_2_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15 Rummagene Transcription Factor Associations 2026 1.0 null GSE199092_2_v_0_ddx5_human RummaGEO Gene Perturbation Signatures -1.0 null GSE146612_1_v_3_amiodarone_human RummaGEO Drug Perturbation Signatures -1.0 null PSMA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48816 GSE162892_3_v_2_isox_human RummaGEO Drug Perturbation Signatures 1.0 null Endometrial disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.294 RD-90-OY66_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.68435 Amygdala TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.297 Fatty acid metabolism Reactome Pathways 2024 1.0 null HC-74-HM63_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -3.23415 Caput epididymis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.537 WEE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31799 GSE202434,GSE202438_13_v_1_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null PMC9974104-jci-133-159940-s017.xlsx-GT3-INCP-GATA3_Co-down-Symbol_GATA3 Rummagene Transcription Factor Associations 2026 1.0 null FLOT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.00663 GSE235066_4_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null Throat TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GSE190384,GSE190386_2_v_8_fulvestrant_human RummaGEO Drug Perturbation Signatures -1.0 null GSE169205_3_v_8_sirt5_human RummaGEO Gene Perturbation Signatures -1.0 null MFN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.96321 GSE125014_6_v_5_enzalutamide_human RummaGEO Drug Perturbation Signatures -1.0 null PMC10322668-Table_7.xlsx-DE_genes_at_early_infection-List_of_de-regulated_genes_at_early_interaction_time_point_of_Dm28c_T_cruzi_THP1_infected_cells_From_Libisch_2020_GLI2 Rummagene Transcription Factor Associations 2026 1.0 null GSE201309_1_v_3_matrine_human RummaGEO Drug Perturbation Signatures -1.0 null CF-91-JY05_0.01uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.220625 E2F6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 47.8654 GSE233647_4_v_6_docetaxel_human RummaGEO Drug Perturbation Signatures -1.0 null GSE48812_2_v_6_sulforaphane_human RummaGEO Drug Perturbation Signatures -1.0 null 496100495_FWM_no dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.54227 GSE220813_0_v_1_zfp750_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE218960_0_v_1_nrf1_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC6356072__F4 PFOCR Pathway Figure Associations 2023 1.0 null GSE178227_1_v_0_tet1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE233679_5_v_8_nicotinamide_human RummaGEO Drug Perturbation Signatures -1.0 null PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_CCRFCEM_ChIP-seq_TCF12 Rummagene Transcription Factor Associations 2026 1.0 null INSM1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.2083 GSE178714_1_v_2_smad2_human RummaGEO Gene Perturbation Signatures 1.0 null GSE190322,GSE190324_3_v_4_rbm4_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE233679_5_v_0_nicotinamide_human RummaGEO Drug Perturbation Signatures -1.0 null Small intestine TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 496100317_FWM_no dementia_no TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.48733 GSE218727_0_v_1_zkscan3_human RummaGEO Gene Perturbation Signatures 1.0 null KA-71-CQ35_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.213549 OE-78-XD40_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.23114 GSE185519_4_v_0_gilteritinib_human RummaGEO Drug Perturbation Signatures 1.0 null GSE237426_0_v_1_eif4a1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Thyroid gland disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.48 GSE125014_1_v_5_enzalutamide_human RummaGEO Drug Perturbation Signatures -1.0 null GA-28-SS67_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.842515 PMC9248879-supp_gr.275831.121_Supplemental_Table_S2.xlsx-TP53-dependent_proteins-GeneName_TP53 Rummagene Transcription Factor Associations 2026 1.0 null GSE124471,GSE124488_1_v_0_lats1_mouse RummaGEO Gene Perturbation Signatures 1.0 null PBX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.32791 GD-46-BU97_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.243359 Arachidonic acid metabolism KEGG Pathways 2026 1.0 null GALM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.34187 AE-95-UU45_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.751169 GSE226259_0_v_1_scd2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE142210_11_v_5_panobinostat_human RummaGEO Drug Perturbation Signatures -1.0 null GSE152055_0_v_1_mpc1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GATA1::TAL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.4959 PMC5637904-PATH-243-193-s016.xlsx-human_down_in_fat_SOX11-Unnamed_6_SOX11 Rummagene Transcription Factor Associations 2026 1.0 null PMC12238561-42003_2025_8460_MOESM2_ESM.xlsx-IDs_S05_LF_C2_3h-Unnamed_5_LTF Rummagene Transcription Factor Associations 2026 1.0 null GSE70499_3_v_2_bmal1_mouse RummaGEO Gene Perturbation Signatures -1.0 null HMG20A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.04095 GSE223008_9_v_2_calhm6_mouse RummaGEO Gene Perturbation Signatures -1.0 null Duodenum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 GSE114284_4_v_0_irf1_human RummaGEO Gene Perturbation Signatures 1.0 null PMC9195629-Table1.xlsx-Supplementary_Table_1-C-FOS_FOS Rummagene Transcription Factor Associations 2026 1.0 null GC-04-UF36_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -3.46807 DA-66-OE69_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -2.07174 GSE233679_6_v_4_nicotinamide_human RummaGEO Drug Perturbation Signatures 1.0 null GSE160817_4_v_9_slamf6_human RummaGEO Gene Perturbation Signatures 1.0 null HE-80-BQ08_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.521812 496100409_FWM_no dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.74722 GSE226114,GSE226116_1_v_0_doxorubicin_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE140997_10_v_1_nsun6_human RummaGEO Gene Perturbation Signatures -1.0 null GSE148066,GSE157787_5_v_10_n4bp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null TF-43-DT71_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.256535 Longissimus thoracis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.779 BE-27-RQ61_0.01uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.13838 GSE119564_1_v_3_zfp217_mouse RummaGEO Gene Perturbation Signatures -1.0 null Arachidonate metabolism Reactome Pathways 2024 1.0 null GSE190384,GSE190386_6_v_8_fulvestrant_human RummaGEO Drug Perturbation Signatures -1.0 null GSE210388_2_v_0_ror2_human RummaGEO Gene Perturbation Signatures -1.0 null CB-16-SY72_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.26193 GSE226249_2_v_8_pirfenidone_human RummaGEO Drug Perturbation Signatures -1.0 null Celiac disease GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.1301 GSE92364_1_v_5_asparaginase_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE198165,GSE198166_6_v_11_zfp266_mouse RummaGEO Gene Perturbation Signatures -1.0 null HOXB8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.69685 GSE158197_2_v_11_egfr_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE154197_1_v_0_ints13_human RummaGEO Gene Perturbation Signatures -1.0 null GSE198165,GSE198166_5_v_11_zfp266_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE131887_5_v_3_doxycycline_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE123638,GSE123639_3_v_1_bortezomib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE70499_0_v_7_bmal1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE143955_1_v_2_ripk1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE208350_0_v_1_fgfr1_human RummaGEO Gene Perturbation Signatures -1.0 null NCAPH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42911 MED27 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.70863 GSE142210_3_v_10_panobinostat_human RummaGEO Drug Perturbation Signatures -1.0 null INTS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.69022 GSE95688_1_v_0_glutathione_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE149264,GSE149267_4_v_1_trp53_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE233679_5_v_9_nicotinamide_human RummaGEO Drug Perturbation Signatures -1.0 null GSE143462_0_v_1_omipalisib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE242199_9_v_5_ntrk2_human RummaGEO Gene Perturbation Signatures -1.0 null GSE148066,GSE157787_8_v_10_n4bp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE162892_3_v_0_isox_human RummaGEO Drug Perturbation Signatures 1.0 null DA-20-VR86_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.348764 chr1_2586971_C_T_b38 GTEx eQTL 2025 1.0 1.20672 ZBTB14 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.4203 496100474_FWM_possible Alzheimer's disease_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.12755 ZIC1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 59.0818 GSE195582_2_v_1_pim1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Omega 6 fatty acids in senescence WikiPathways Pathways 2024 1.0 null GSE138938_1_v_2_foxp2_human RummaGEO Gene Perturbation Signatures -1.0 null GSE123638,GSE123639_2_v_1_bortezomib_human RummaGEO Drug Perturbation Signatures -1.0 null PMC9424213-41467_2022_32537_MOESM6_ESM.xlsx-siHNRNPK_cyto-DEGs_for_hnRNPK_KD_cytoplasmic_RNA_of_HeLa_cells_AR Rummagene Transcription Factor Associations 2026 1.0 null Myelencephalon TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.041 GSE207135_1_v_0_sod2_human RummaGEO Gene Perturbation Signatures -1.0 null GSE246053_4_v_2_hnf4a_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE149621_0_v_1_olaparib_human RummaGEO Drug Perturbation Signatures -1.0 null PPP1R2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.07492 ZBTB7C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.681 IMMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.33784 DF-00-DK69_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.311434 GSE100886,GSE100893_1_v_3_parp14_mouse RummaGEO Gene Perturbation Signatures 1.0 null CB-44-RT90_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.447323 PMC5637904-PATH-243-193-s016.xlsx-human_down_in_fat_SOX11-Table_S5C_Downregulated_genes_in_tumours_from_DCIS-SOX11_cells_compared_to_DCIS-lacZ_cells_injected_into_mammary_fat_pad_SOX11 Rummagene Transcription Factor Associations 2026 1.0 null GSE261563_9_v_1_atrx_human RummaGEO Gene Perturbation Signatures -1.0 null TFDP1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.6761 prostanoid biosynthetic process GO Biological Process Annotations 2023 1.0 null GSE208350_4_v_1_fgfr1_human RummaGEO Gene Perturbation Signatures 1.0 null GSE127790_5_v_3_zcchc8_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE247764_1_v_2_nell2_mouse RummaGEO Gene Perturbation Signatures 1.0 null 496100277_FWM_no dementia_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.15192 GSE216540_1_v_6_fulvestrant_human RummaGEO Drug Perturbation Signatures -1.0 null GSE120612_6_v_3_etoposide_human RummaGEO Drug Perturbation Signatures 1.0 null 496100543_FWM_probable Alzheimer's disease_TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.30449 PMC10185556-41467_2023_38439_MOESM3_ESM.xlsx-ST12_cg_gene_assoc_visc_TAD-target_gene_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null GSE96641_3_v_4_esrp2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE137818_3_v_6_brca2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.923 TRABD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.03118 GC-04-UF36_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.53753 GSE205316,GSE205317_2_v_1_nrip1_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC10319804-41467_2023_38747_MOESM10_ESM.xlsx-circARID1A_KD_genes_up-gene_name_AR Rummagene Transcription Factor Associations 2026 1.0 null prostaglandin metabolic process GO Biological Process Annotations 2023 1.0 null Disease of cellular proliferation DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.043 GSE128076_1_v_0_doxycycline_human RummaGEO Drug Perturbation Signatures -1.0 null GSE107854_2_v_0_prmt5_mouse RummaGEO Gene Perturbation Signatures -1.0 null XD-44-FJ34_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.2435 Cervix - Endocervix GTEx Tissue Gene Expression Profiles 2023 1.0 2.71798 OB-20-LP90_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.478902 Extravillous trophoblast cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.608 KAT2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.0641 TFAP2A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 153.752 PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC Rummagene Transcription Factor Associations 2026 1.0 null GSE108614,GSE108615_3_v_2_setd1a_mouse RummaGEO Gene Perturbation Signatures 1.0 null BB-62-SZ35_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.03936 GSE130715_2_v_3_budesonide_human RummaGEO Drug Perturbation Signatures 1.0 null PMC12439337-thnov15p9091s1.pdf-111-ENSG00000180806_HOXC9 Rummagene Transcription Factor Associations 2026 1.0 null GSE169152_3_v_2_ibrutinib_human RummaGEO Drug Perturbation Signatures 1.0 null Endocrine system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.48 KNTC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.00919 GSE216540_0_v_6_fulvestrant_human RummaGEO Drug Perturbation Signatures -1.0 null GSE152441,GSE152442_0_v_3_folic acid_human RummaGEO Drug Perturbation Signatures -1.0 null Thyroid gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GSE97278,GSE97280_2_v_1_nsd2_mouse RummaGEO Gene Perturbation Signatures 1.0 null MYF5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.3708 GSE198165,GSE198166_0_v_1_zfp266_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE231524,GSE231526_0_v_1_dusp6_human RummaGEO Gene Perturbation Signatures -1.0 null GSE213588_10_v_2_trametinib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE211983_1_v_3_nicotine_mouse RummaGEO Drug Perturbation Signatures -1.0 null PMC9218776-ADVS-9-2104640-s002.xlsx-SIM_-_Nurr1-Unnamed_1_SIM2 Rummagene Transcription Factor Associations 2026 1.0 null PMC10641274-mmc2.xlsx-FOXK1_Untreated-SYMBOL_FOXK1 Rummagene Transcription Factor Associations 2026 1.0 null GSE174498,GSE174500_3_v_8_asparaginase_human RummaGEO Drug Perturbation Signatures -1.0 null GSE171837_0_v_1_bortezomib_human RummaGEO Drug Perturbation Signatures 1.0 null GSE169356_2_v_1_ivermectin_human RummaGEO Drug Perturbation Signatures -1.0 null GSE242083,GSE242098_3_v_5_med1_human RummaGEO Gene Perturbation Signatures -1.0 null GC-04-UF36_0.01uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.285697 GSE198165,GSE198166_0_v_2_zfp266_mouse RummaGEO Gene Perturbation Signatures 1.0 null AA-56-JY17_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.231541 GSE162892_4_v_0_sox9_human RummaGEO Gene Perturbation Signatures 1.0 null GSE169205_0_v_2_sirt5_human RummaGEO Gene Perturbation Signatures -1.0 null COPS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.62661 GSE183041_1_v_0_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null GSE120612_7_v_1_etoposide_human RummaGEO Drug Perturbation Signatures -1.0 null GSE223008_7_v_3_calhm6_mouse RummaGEO Gene Perturbation Signatures 1.0 null CE-15-YU05_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.214647 MCM8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.40915 EDC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38943 GSE222598_1_v_0_sf3b4_human RummaGEO Gene Perturbation Signatures -1.0 null PMC6718408-41467_2019_11884_MOESM6_ESM.xlsx-TAD_genes_ST-EPN-RELA-Unnamed_4_RELA Rummagene Transcription Factor Associations 2026 1.0 null GSE128563_2_v_6_venetoclax_human RummaGEO Drug Perturbation Signatures 1.0 null SAAL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.06163 GSE235390_4_v_0_lurbinectedin_human RummaGEO Drug Perturbation Signatures -1.0 null Hypothyroidism DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.48 GSE102505_4_v_3_tunicamycin_human RummaGEO Drug Perturbation Signatures -1.0 null GSE148200_4_v_2_gemcitabine_human RummaGEO Drug Perturbation Signatures -1.0 null KE-73-XV62_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.662551 GSE160817_5_v_6_slamf6_human RummaGEO Gene Perturbation Signatures -1.0 null GSE120370_0_v_3_thrombin_mouse RummaGEO Drug Perturbation Signatures 1.0 null Erythroleukemia cell TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GSE120612_7_v_5_etoposide_human RummaGEO Drug Perturbation Signatures -1.0 null GSE193354_0_v_1_saraf_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE240030,GSE252532_0_v_2_atrx_human RummaGEO Gene Perturbation Signatures -1.0 null Zbtb2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.0059 GSE211357_2_v_0_atg7_human RummaGEO Gene Perturbation Signatures 1.0 null GSE125014_6_v_2_enzalutamide_human RummaGEO Drug Perturbation Signatures -1.0 null GSE223008_4_v_8_calhm6_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE169205_0_v_1_sirt5_human RummaGEO Gene Perturbation Signatures -1.0 null GSE154197_1_v_2_ints13_human RummaGEO Gene Perturbation Signatures -1.0 null GSE77108_6_v_1_saha_human RummaGEO Drug Perturbation Signatures -1.0 null GSE87412,GSE92423_2_v_1_dnmt3a_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE167886_2_v_0_chd7_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC7585942-mmc4.xlsx-RBM10_KD-Unnamed_3_AR Rummagene Transcription Factor Associations 2026 1.0 null SIRT5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.19662 GSE160817_3_v_6_slamf6_human RummaGEO Gene Perturbation Signatures -1.0 null GSE233679_5_v_3_nicotinamide_human RummaGEO Drug Perturbation Signatures -1.0 null Thalamus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.027 GSE196117_1_v_11_clarithromycin_human RummaGEO Drug Perturbation Signatures -1.0 null FUNDC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.83719 Uniplex complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.543 increased red blood cell distribution width MGI Mouse Phenotype Associations 2023 1.0 null GSE148200_1_v_2_gemcitabine_human RummaGEO Drug Perturbation Signatures -1.0 null GSE169152_5_v_6_ibrutinib_human RummaGEO Drug Perturbation Signatures -1.0 null Cytotoxic T-lymphocyte TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.155 LA-42-ER00_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.597827 KLF16 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 103.161 BTF3L4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02034 GSE96641_3_v_0_esrp2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE160817_2_v_1_slamf6_human RummaGEO Gene Perturbation Signatures -1.0 null PMC8569982-41065_2021_205_MOESM1_ESM.xlsx-mono_THP1_a2b_tpm1-gene_GLI2 Rummagene Transcription Factor Associations 2026 1.0 null GSE202310_1_v_0_ube3d_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE169152_5_v_4_ibrutinib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE223008_4_v_2_calhm6_mouse RummaGEO Gene Perturbation Signatures -1.0 null Cerebral gyrus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.138 LSG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10263 Oviduct TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 GSE223008_11_v_3_calhm6_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE203485_1_v_0_zdhhc2_human RummaGEO Gene Perturbation Signatures 1.0 null GSE197562_2_v_3_nox4_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE140997_10_v_7_nsun6_human RummaGEO Gene Perturbation Signatures -1.0 null GSE84148,GSE96938_3_v_1_nrros_mouse RummaGEO Gene Perturbation Signatures 1.0 null WB-48-EF24_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.440988 GD-79-TW34_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.66623 CB-16-SY72_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.627493 Cholangitis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.592 GSE77108_3_v_2_saha_human RummaGEO Drug Perturbation Signatures -1.0 null GSE146840,GSE146842_0_v_2_qrich1_human RummaGEO Gene Perturbation Signatures -1.0 null GSE99875_2_v_0_everolimus_human RummaGEO Drug Perturbation Signatures 1.0 null CB-69-DJ58_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.229547 KLF14 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 84.8934 GSE124097_3_v_0_trem2_mouse RummaGEO Gene Perturbation Signatures 1.0 null DD-65-SA37_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.234028 STK35 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.21316 GSE189356_5_v_6_dexamethasone_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE202434,GSE202438_3_v_11_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null BC-14-CG34_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.2328 Metabolism of lipids Reactome Pathways 2024 1.0 null GSE169356_2_v_5_ivermectin_human RummaGEO Drug Perturbation Signatures -1.0 null CB-31-UO16_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.58991 GSE148695,GSE167281_2_v_1_satb2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE202434,GSE202438_13_v_0_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null AC-55-XA97_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.24773 GSE207122_1_v_0_metformin_human RummaGEO Drug Perturbation Signatures -1.0 null GSE213588_8_v_4_trametinib_human RummaGEO Drug Perturbation Signatures -1.0 null CB-16-SY72_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.82179 PMC12238561-42003_2025_8460_MOESM2_ESM.xlsx-IDs_S27_LF_C2_24h-Unnamed_5_LTF Rummagene Transcription Factor Associations 2026 1.0 null PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-10_MYB Rummagene Transcription Factor Associations 2026 1.0 null Respiratory system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.674 SA-31-VB03_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.271578 GSE199660_1_v_2_secretin_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE202434,GSE202438_4_v_1_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null CC-04-WK34_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.357063 GSE137325_3_v_0_copanlisib_human RummaGEO Drug Perturbation Signatures -1.0 null DB-54-GQ68_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -2.27636 ZFP69B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24687 Head TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 AF-41-QY60_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.330495 CC-44-MG29_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.216458 PPP1R14A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02612 GSE149075_8_v_11_foxa2_mouse RummaGEO Gene Perturbation Signatures 1.0 null EA-62-MI89_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.217775 PMC5095001-oncotarget-07-36293-s002.xlsx-Table_S2-Table_S2_MYCN-correlated_genes_and_their_correlations_with_other_transcription_factors_MYCN Rummagene Transcription Factor Associations 2026 1.0 null RPL34 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.94626 FARSB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.34618 AD-16-HL96_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.28034 GSE248501_1_v_0_mst1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE179531_1_v_0_metformin_mouse RummaGEO Drug Perturbation Signatures 1.0 null Lymphatic system cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.043 DCAF12L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.05593 GSE169205_0_v_5_sirt5_human RummaGEO Gene Perturbation Signatures -1.0 null GSE132694,GSE132717_0_v_2_meis1_human RummaGEO Gene Perturbation Signatures -1.0 null GSE203308_7_v_0_brf1_mouse RummaGEO Gene Perturbation Signatures -1.0 null FE-82-WB22_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -3.31392 GSE199092_1_v_0_ddx5_human RummaGEO Gene Perturbation Signatures -1.0 null Nose disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.674 GSE148692,GSE148695_1_v_3_satb2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE213632_3_v_6_acod1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE64513_0_v_1_foxd3_human RummaGEO Gene Perturbation Signatures 1.0 null CC-03-PW00_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.445888 Whole body TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 PMC12238561-42003_2025_8460_MOESM2_ESM.xlsx-IDs_S01_LF_C1_3h-Unnamed_5_LTF Rummagene Transcription Factor Associations 2026 1.0 null GSE202434,GSE202438_13_v_11_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null GSE134375_6_v_5_stat3_human RummaGEO Gene Perturbation Signatures 1.0 null GSE229344_1_v_0_cyb5r3_human RummaGEO Gene Perturbation Signatures -1.0 null GSE197948_2_v_0_atp7b_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE200320_1_v_0_mfge8_mouse RummaGEO Gene Perturbation Signatures 1.0 null Cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.043 Musculoskeletal system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.902 WE-48-PP43_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.511723 GSE96777,GSE96778_3_v_2_zbtb4_human RummaGEO Gene Perturbation Signatures -1.0 null SMARCD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31843 GSE115763_3_v_1_klf6_human RummaGEO Gene Perturbation Signatures -1.0 null GSE195503_3_v_2_progesterone_human RummaGEO Drug Perturbation Signatures -1.0 null Intestinal disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.923 NLE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.00138 GSE160817_4_v_1_slamf6_human RummaGEO Gene Perturbation Signatures -1.0 null GSE180200,GSE180201_3_v_0_qpctl_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE126463_1_v_3_pomalidomide_human RummaGEO Drug Perturbation Signatures -1.0 null Tacrolimus DeepCoverMOA Drug Mechanisms of Action -1.0 -0.33 HEY2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1714 496100352_FWM_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.43993 GSE126463_6_v_3_pomalidomide_human RummaGEO Drug Perturbation Signatures -1.0 null GSE193177_1_v_2_st266_mouse RummaGEO Drug Perturbation Signatures 1.0 null QA-50-YO37_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.302765 ZKSCAN3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 49.9524 GSE135514_8_v_7_dasatinib_human RummaGEO Drug Perturbation Signatures -1.0 null PA-75-VL17_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.249629 PMC11868582-41423_2025_1264_MOESM4_ESM.xlsx-Table_S10-Table_S10_List_of_FICZ-induced_or_FICZ-suppressed_and_OVOL1-dependent_genes_OVOL1 Rummagene Transcription Factor Associations 2026 1.0 null GSE133763_0_v_1_chd1_human RummaGEO Gene Perturbation Signatures -1.0 null GB-46-CK08_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.47246 GSE237040_2_v_1_notch3_mouse RummaGEO Gene Perturbation Signatures -1.0 null TFAP4::ETV1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.9036 GSE180200,GSE180201_3_v_9_qpctl_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE232624_4_v_5_ethanol_human RummaGEO Drug Perturbation Signatures 1.0 null GSE217452_3_v_1_docetaxel_human RummaGEO Drug Perturbation Signatures 1.0 null PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-9_MYB Rummagene Transcription Factor Associations 2026 1.0 null GSE70935_1_v_0_cyfip1_human RummaGEO Gene Perturbation Signatures 1.0 null GSE239688_2_v_1_canagliflozin_human RummaGEO Drug Perturbation Signatures -1.0 null 496100596_FWM_dementia_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.41609 GSE95688_7_v_2_glutathione_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE223008_7_v_8_calhm6_mouse RummaGEO Gene Perturbation Signatures -1.0 null Neuroepithelioma cell TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GSE190235_3_v_2_foxo3_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE92457_9_v_10_ethanol_mouse RummaGEO Drug Perturbation Signatures 1.0 null Pineal gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.029 LRFN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.13841 GSE169356_0_v_4_ivermectin_human RummaGEO Drug Perturbation Signatures -1.0 null DBN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34007 GSE224096_2_v_0_cocaine_human RummaGEO Drug Perturbation Signatures 1.0 null MYB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.8382 RBAK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.41371 GSE190186,GSE190188_8_v_5_apoe_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE235066_7_v_2_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null RCAN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18539 prostaglandin-F synthase activity GO Molecular Function Annotations 2023 1.0 null PMC10561055-mmc3.xlsx-LPS_T0-gene_name_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null ALG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.77398 GSE233679_12_v_2_nicotinamide_human RummaGEO Drug Perturbation Signatures 1.0 null PMC10781639-41586_2023_6618_MOESM4_ESM.xlsx-ST12-Unnamed_5_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null GSE121198,GSE129782_1_v_0_arid1a_human RummaGEO Gene Perturbation Signatures -1.0 null Eicosanoid synthesis WikiPathways Pathways 2024 1.0 null PMC8350019-mmc2.xlsx-DESeq2_Pten_vs_control_batch_LF-ENSG_LTF Rummagene Transcription Factor Associations 2026 1.0 null GSE203158_5_v_13_aire_mouse RummaGEO Gene Perturbation Signatures -1.0 null VEZF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 69.8138 PMC8350019-mmc2.xlsx-DESeq2_Pten_vs_control_batch_LF-gene_name_LTF Rummagene Transcription Factor Associations 2026 1.0 null GSE198165,GSE198166_9_v_2_zfp266_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC9013128-NIHMS1795992-supplement-6.xlsx-ARID2_MUT_Dowregulated-Gene_name_ARID2 Rummagene Transcription Factor Associations 2026 1.0 null Synthesis of Prostaglandins (PG) and Thromboxanes (TX) Reactome Pathways 2024 1.0 null Autoimmune disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.923 GSE148692,GSE148695_7_v_6_satb2_mouse RummaGEO Gene Perturbation Signatures 1.0 null FF-28-ES17_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.11424 FA-63-WI26_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -2.27998 GSE216538_1_v_4_mrs2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE160817_5_v_1_slamf6_human RummaGEO Gene Perturbation Signatures -1.0 null GSE235066_7_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null PMC12775252-18_2025_5991_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_2_Up-_and_down-regulated_genes_in_TCF7L2-depleted_EVT_compared_to_control_EVT_TCF7L2 Rummagene Transcription Factor Associations 2026 1.0 null Allergic disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.674 PMC12774775-mmc2.xlsx-PAR_RARG_merge_q5_Narrow_subKO-ENSEMBL_ID_RARG Rummagene Transcription Factor Associations 2026 1.0 null RAB40C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.37254 GSE220520_1_v_7_ethanol_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE216273,GSE216292_14_v_3_palbociclib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE202434,GSE202438_4_v_14_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null NF-21-HQ00_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.678836 ZBED4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 153.792 GSE107505_0_v_2_nanog_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE119345_2_v_3_bexarotene_human RummaGEO Drug Perturbation Signatures -1.0 null Endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GSE131649_6_v_8_hemin_human RummaGEO Drug Perturbation Signatures -1.0 null FE-56-PV35_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.974401 Nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 METTL25B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.36296 EIF3J CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.93671 GSE210885_3_v_1_klf4_mouse RummaGEO Gene Perturbation Signatures 1.0 null KF-18-RY71_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.905129 S0-EE-Y7IR_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.431798 GSE162276_4_v_3_pparg_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE77108_8_v_9_saha_human RummaGEO Drug Perturbation Signatures 1.0 null GSE179974_3_v_5_carboplatin_mouse RummaGEO Drug Perturbation Signatures 1.0 null JD-81-YX02_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.212668 GSE112762,GSE112767_1_v_3_dgcr8_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC10760404-NIHMS1688779-supplement-Supplementary_Table_S6.xlsx-EMP_CREB_Targets-symbol_CREB1 Rummagene Transcription Factor Associations 2026 1.0 null ERF::NHLH1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.162 PLAGL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 71.1081 PMC4515859__F3 PFOCR Pathway Figure Associations 2023 1.0 null GSE148692,GSE148695_7_v_4_satb2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE211151_1_v_4_progesterone_human RummaGEO Drug Perturbation Signatures -1.0 null GSE146982_7_v_5_gpd1_human RummaGEO Gene Perturbation Signatures 1.0 null GSE62843,GSE64371_2_v_3_furan_mouse RummaGEO Drug Perturbation Signatures -1.0 null PMC11611169-pone.0314092.s001.docx-3-PPARG_PPARG Rummagene Transcription Factor Associations 2026 1.0 null ficolin-1-rich granule COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.751 GSE161170,GSE161268_0_v_2_med1_human RummaGEO Gene Perturbation Signatures 1.0 null Primary immunodeficiency disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.923 GSE126463_1_v_2_pomalidomide_human RummaGEO Drug Perturbation Signatures -1.0 null GSE193541_1_v_2_nifurtimox_human RummaGEO Drug Perturbation Signatures 1.0 null PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_U87MG_KD-GeneID_AR Rummagene Transcription Factor Associations 2026 1.0 null PMC10561055-mmc3.xlsx-LPS_T0-hgnc_symbol_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null MEOX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.04621 496100436_FWM_no dementia_no TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.22282 EBF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.2919 MTF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.2347 GSE145476_2_v_0_hopx_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE199255,GSE199356_4_v_1_pds5a_mouse RummaGEO Gene Perturbation Signatures -1.0 null TMEM161A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.09317 GSE200839,GSE233826_5_v_0_tnrc18_human RummaGEO Gene Perturbation Signatures -1.0 null GSE162276_2_v_0_rosiglitazone_mouse RummaGEO Drug Perturbation Signatures 1.0 null Ar JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 35.3248 GSE213588_10_v_6_trametinib_human RummaGEO Drug Perturbation Signatures -1.0 null 1011_C18ORF21_P1P2 Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures 1.0 2.04307 Cingulate gyrus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.138 DDX42 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.06403 PMC12224929-ADVS-12-2416784-s006.xlsx-DEG_circGLIS3_KD-Unnamed_6_AR Rummagene Transcription Factor Associations 2026 1.0 null Brain - Spinal cord (cervical c-1) GTEx Tissue Gene Expression Profiles 2023 1.0 1.035 HUPT3_PANCREAS CCLE Cell Line Proteomics 1.0 10.7463 FE-10-KQ78_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.761436 PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT38_Protein_cis-instrument_MR-Unnamed_2_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null BD-49-MD69_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.25564 GSE131649_4_v_8_hemin_human RummaGEO Drug Perturbation Signatures -1.0 null N4BP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.07547 GSE114284_1_v_5_irf1_human RummaGEO Gene Perturbation Signatures 1.0 null Biliary tract disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.592 RAP1GAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.88862 GSE190384,GSE190386_2_v_4_fulvestrant_human RummaGEO Drug Perturbation Signatures -1.0 null GSE213219_2_v_3_st3gal3_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE110178_2_v_3_tranylcypromine_mouse RummaGEO Drug Perturbation Signatures -1.0 null RPS27A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.07481 PPM1D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22435 Gli1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 39.2276 BF-04-NQ13_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.202281 GSE246184,GSE246195_0_v_1_sin3a_mouse RummaGEO Gene Perturbation Signatures 1.0 null oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO Molecular Function Annotations 2025 1.0 null B-cell lymphoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.043 OC-10-FB51_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.337088 GSE131649_2_v_3_hemin_human RummaGEO Drug Perturbation Signatures -1.0 null GSE148066,GSE157787_0_v_4_n4bp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE196505,GSE196507_3_v_2_kdm2b_human RummaGEO Gene Perturbation Signatures 1.0 null GSE138789_0_v_1_metformin_human RummaGEO Drug Perturbation Signatures -1.0 null GSE217452_3_v_0_docetaxel_human RummaGEO Drug Perturbation Signatures 1.0 null Allergic rhinitis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.674 PMC10641274-mmc2.xlsx-FOXK1_Untreated-ENSEMBL_FOXK1 Rummagene Transcription Factor Associations 2026 1.0 null GSE157594_6_v_2_nicotinamide_mouse RummaGEO Drug Perturbation Signatures -1.0 null PMC8047323-Table_3.xlsx-Venn_581_LPS_T24_vs_LPS_T0-GeneSymbol_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null chr1_2597921_G_A_b38 GTEx eQTL 2025 1.0 1.44604 GSE216043_11_v_6_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null AC-84-QG99_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.284645 Thymus TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GSE200839,GSE233826_2_v_6_tnrc18_human RummaGEO Gene Perturbation Signatures -1.0 null NCIH716_LARGE_INTESTINE CCLE Cell Line Proteomics 1.0 7.49126 GSE123734_1_v_0_mien1_human RummaGEO Gene Perturbation Signatures 1.0 null YY1-33199912-293T-HUMAN-KIDNEYEMBRYO ChEA Transcription Factor Targets 2022 1.0 null GSE127790_11_v_3_zcchc8_mouse RummaGEO Gene Perturbation Signatures -1.0 null HD-29-LW24_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.671569 496100362_FWM_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.95943 PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-Partitions_EPC1-PHF1-FLAG-Unnamed_20_PHF1 Rummagene Transcription Factor Associations 2026 1.0 null Autoimmune thyroiditis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.339 AD-16-HL96_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.72114 GSE184210_0_v_3_glucagon_mouse RummaGEO Drug Perturbation Signatures 1.0 null PMC6858560-NIHMS1538530-supplement-Supplementary_Tables.xlsx-Supplementary_Table_22-Supplementary_Table_22_Aberrant_Splicing_Events_in_TET2_SRSF2_co-mutated_AML_Patients_from_the_Beat-AML_cohort_TET2 Rummagene Transcription Factor Associations 2026 1.0 null ZE-45-CG69_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.433345 GC-04-UF36_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -2.77252 Diffuse large B-cell lymphoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.043 GSE132948,GSE132949_0_v_5_msi2_mouse RummaGEO Gene Perturbation Signatures 1.0 null FB-66-UU47_0.01uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.239175 GSE143743_0_v_2_c9orf72_human RummaGEO Gene Perturbation Signatures -1.0 null GSE149264,GSE149267_2_v_1_trp53_mouse RummaGEO Gene Perturbation Signatures 1.0 null Vaginal discharge DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.481 GSE171837_0_v_2_bortezomib_human RummaGEO Drug Perturbation Signatures 1.0 null GSE162276_4_v_3_rosiglitazone_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE142210_2_v_10_panobinostat_human RummaGEO Drug Perturbation Signatures -1.0 null GSE224742_0_v_1_slc1a5_human RummaGEO Gene Perturbation Signatures 1.0 null GSE158834_2_v_9_palmitic acid_human RummaGEO Drug Perturbation Signatures -1.0 null PMC12769604-13402_2025_1147_MOESM6_ESM.xlsx-Table_S4_3_Venn-Tumor_AND_Prognosis_NOT_Scissor_NR4A2 Rummagene Transcription Factor Associations 2026 1.0 null GSE122215,GSE122217_0_v_2_peg10_mouse RummaGEO Gene Perturbation Signatures -1.0 null Bone disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.902 PMC10641274-mmc2.xlsx-FOXK1_Insulin-ENSEMBL_FOXK1 Rummagene Transcription Factor Associations 2026 1.0 null GSE125014_1_v_2_enzalutamide_human RummaGEO Drug Perturbation Signatures -1.0 null AC-30-XU83_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.401859 GSE247862,GSE247863_0_v_1_eomes_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC13137955-ijbsv22p4243s2.xlsx-Sheet1-hTFtarget_E2F3_E2F3 Rummagene Transcription Factor Associations 2026 1.0 null NFKB2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 52.8867 GSE198165,GSE198166_0_v_4_zfp266_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE159678_4_v_3_chloroquine_human RummaGEO Drug Perturbation Signatures -1.0 null GSE135030_3_v_1_fludarabine_human RummaGEO Drug Perturbation Signatures -1.0 null GSE176008_7_v_2_azacitidine_human RummaGEO Drug Perturbation Signatures 1.0 null Immune system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.923 PC-62-AQ92_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.269126 TFAP4::FLI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 52.3745 MAZ JASPAR Predicted Human Transcription Factor Targets 2025 1.0 95.2262 RE-99-TA30_0.01uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.387862 GSE142210_3_v_5_panobinostat_human RummaGEO Drug Perturbation Signatures -1.0 null MGAT4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48519 Trunk TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 KA-81-AG66_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.347522 GSE148692,GSE148695_7_v_3_satb2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE72895,GSE72896_0_v_1_progesterone_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE158969_1_v_2_trastuzumab_human RummaGEO Drug Perturbation Signatures -1.0 null GSE92457_9_v_12_ethanol_mouse RummaGEO Drug Perturbation Signatures 1.0 null BE-79-QU25_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.601389 GSE114883_1_v_4_romidepsin_human RummaGEO Drug Perturbation Signatures 1.0 null Helper T-lymphocyte TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.076 GSE215086_5_v_0_batf_human RummaGEO Gene Perturbation Signatures -1.0 null JE-72-KV75_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.320849 PMC12238561-42003_2025_8460_MOESM2_ESM.xlsx-IDs_S23_LF_C1_24h-Unnamed_5_LTF Rummagene Transcription Factor Associations 2026 1.0 null GSE140937,GSE140938_1_v_2_slfn11_human RummaGEO Gene Perturbation Signatures 1.0 null SLC16A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.0108 GSE113106_2_v_1_dnm2_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-2_MYB Rummagene Transcription Factor Associations 2026 1.0 null GSE202434,GSE202438_13_v_5_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null SPTAN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.30736 CENPM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.29808 CRYZ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.39519 GSE149035_7_v_0_hepacam_human RummaGEO Gene Perturbation Signatures -1.0 null GSE127790_11_v_2_zcchc8_mouse RummaGEO Gene Perturbation Signatures -1.0 null AC-05-MR83_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.274115 GSE70499_0_v_2_bmal1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE96777,GSE96778_1_v_0_zbtb4_human RummaGEO Gene Perturbation Signatures 1.0 null ADM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.03892 GSE136622_7_v_3_srpk3_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE148066,GSE157787_0_v_7_n4bp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null PGH2 MW Enzyme Metabolite Associations 1.0 null GSE189609_1_v_0_hax1_human RummaGEO Gene Perturbation Signatures 1.0 null GSE111102,GSE111105_3_v_7_pparg_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE158834_12_v_9_palmitic acid_human RummaGEO Drug Perturbation Signatures -1.0 null GSE238116_1_v_2_egr1_human RummaGEO Gene Perturbation Signatures 1.0 null PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Combined-MYB_Combined_sgRNA_MYB Rummagene Transcription Factor Associations 2026 1.0 null GSE137818_2_v_6_brca2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Spleen GTEx Tissue Gene Expression Profiles 2023 1.0 1.15461 PPP1R7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.40108 AD-16-HL96_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.661 THAP1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.6381 Tfcp2l1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 36.9461 prostanoid biosynthetic process GO Biological Process Annotations 2025 1.0 null Prostaglandin and leukotriene metabolism in senescence WikiPathways Pathways 2024 1.0 null GSE171292_1_v_0_ehhadh_mouse RummaGEO Gene Perturbation Signatures -1.0 null PLAG1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 160.167 RPP38 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47311 GSE142210_2_v_1_panobinostat_human RummaGEO Drug Perturbation Signatures 1.0 null GSE193177_1_v_3_st266_mouse RummaGEO Drug Perturbation Signatures 1.0 null Ibrutinib2 DeepCoverMOA Drug Mechanisms of Action -1.0 -1.1 GSE213588_8_v_2_trametinib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE185922_1_v_2_riok2_human RummaGEO Gene Perturbation Signatures -1.0 null GSE125007,GSE125008_10_v_0_uhrf1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE140997_4_v_6_nsun6_human RummaGEO Gene Perturbation Signatures 1.0 null SAP18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58299 PMC11925450-elife-96850-supp2.xlsx-DNMT1_KO_vs_DNMT1_L1TD1_dKO_res-Unnamed_0_DNMT1 Rummagene Transcription Factor Associations 2026 1.0 null YD-49-HM53_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.312296 Bile duct disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.592 GSE137818_5_v_6_brca2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Nr1h4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.526 PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Unnamed_2_ATF4 Rummagene Transcription Factor Associations 2026 1.0 null GSE233679_5_v_13_nicotinamide_human RummaGEO Drug Perturbation Signatures -1.0 null Gastrodermis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.809 GSE131588,GSE131690_1_v_0_setd2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE197562_0_v_3_nox4_mouse RummaGEO Gene Perturbation Signatures -1.0 null Arthritis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.902 SP9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 83.0823 PTK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.49267 ALG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02245 prostaglandin biosynthetic process GO Biological Process Annotations 2023 1.0 null GSE233679_14_v_15_nicotinamide_human RummaGEO Drug Perturbation Signatures -1.0 null Teratocarcinoma cell TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 E2F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.133 GSE240386,GSE242143_8_v_6_morc2_human RummaGEO Gene Perturbation Signatures -1.0 null PMC9038526-mmc1.xlsx-postCOVID_LPS_vs_healthy_L-symbols_98_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null GSE140322_0_v_2_imatinib_human RummaGEO Drug Perturbation Signatures 1.0 null ZNF121 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31542 prostaglandin biosynthetic process GO Biological Process Annotations 2025 1.0 null GSE174498,GSE174500_5_v_8_asparaginase_human RummaGEO Drug Perturbation Signatures -1.0 null GSE216043_3_v_5_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null GSE207787_1_v_2_pdha1_human RummaGEO Gene Perturbation Signatures -1.0 null PMC9038526-mmc1.xlsx-postCOVID_ctr_vs_LPS-symbols_98_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null GSE193258,GSE193259_9_v_15_osimertinib_human RummaGEO Drug Perturbation Signatures 1.0 null PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-5_MYB Rummagene Transcription Factor Associations 2026 1.0 null SP3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 90.7635 ZNF232 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28895 GSE246053_1_v_2_hnf4a_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE126463_4_v_2_pomalidomide_human RummaGEO Drug Perturbation Signatures -1.0 null PMC5651844-41467_2017_1173_MOESM5_ESM.xlsx-Down_genes_shY2-1-Supplementary_Data_1_Down_regulated_genes_in_ShY2_KD_cells_AR Rummagene Transcription Factor Associations 2026 1.0 null Shell gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.722 GSE133691_1_v_3_lgr5_mouse RummaGEO Gene Perturbation Signatures 1.0 null IA-76-ZU47_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.519004 ZNF524 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.1325 SLC1A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.0025 GSE152055_2_v_3_mpc1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE197555_1_v_3_trametinib_human RummaGEO Drug Perturbation Signatures -1.0 null GE-53-SM76_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.616727 KLF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 94.2637 GSE90552_1_v_0_valproic acid_human RummaGEO Drug Perturbation Signatures 1.0 null Mitochondrion COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 GSE148252_7_v_6_npas4_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE235066_7_v_3_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null GSE131649_2_v_0_hemin_human RummaGEO Drug Perturbation Signatures -1.0 null Rheumatoid arthritis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.902 Seminal vesicle fluid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.032 GSE103068_0_v_3_volasertib_human RummaGEO Drug Perturbation Signatures -1.0 null PMC9396374-Table_4.XLSX-AR_related_genes_from_GeneCards-gene_symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null TD-29-IN36_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.10293 PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Unnamed_1_ATF4 Rummagene Transcription Factor Associations 2026 1.0 null GSE216147_0_v_1_rbm20_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE69244_1_v_0_j147_mouse RummaGEO Drug Perturbation Signatures -1.0 null GLMN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.613 GSE217776,GSE217829_1_v_6_sgf29_human RummaGEO Gene Perturbation Signatures 1.0 null PUS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.14352 GSE142210_3_v_6_panobinostat_human RummaGEO Drug Perturbation Signatures -1.0 null RAD51D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.30821 GSE131798,GSE131804_2_v_0_igf1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE203329_0_v_1_mettl5_human RummaGEO Gene Perturbation Signatures -1.0 null increased red blood cell distribution width IMPC Knockout Mouse Phenotypes 1.0 null GSE149123,GSE149128_2_v_0_cdk7_mouse RummaGEO Gene Perturbation Signatures -1.0 null Caudate nucleus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.002 GSE228261_0_v_1_elesclomol_human RummaGEO Drug Perturbation Signatures 1.0 null 496100577_FWM_probable Alzheimer's disease_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.57155 GSE152441,GSE152442_7_v_2_folic acid_human RummaGEO Drug Perturbation Signatures 1.0 null GSE235066_4_v_2_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null NDUFA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.59777 BD-69-GX17_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.396848 PMC8350019-mmc2.xlsx-DESeq2_Pten_vs_control_batch_LF-ensembl_LTF Rummagene Transcription Factor Associations 2026 1.0 null 496100278_FWM_no dementia_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.56421 GSE201239_6_v_1_fmr1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE128076_1_v_3_doxycycline_human RummaGEO Drug Perturbation Signatures -1.0 null Taste bud TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.818 Inflammatory bowel disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.923 GSE81803,GSE81912_4_v_1_fmr1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Liver disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.327 TP53INP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.0016 E2F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.6928 GSE180200,GSE180201_3_v_1_qpctl_mouse RummaGEO Gene Perturbation Signatures 1.0 null MGA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.5361 ZNF692 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.8173 POLR1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11528 GB-06-BA49_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.430822 496100455_FWM_dementia_TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.35961 GSE133691_2_v_0_lgr5_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE116810_2_v_1_selinexor_human RummaGEO Drug Perturbation Signatures -1.0 null GSE223008_4_v_12_calhm6_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE162739_8_v_1_bap1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE154767_4_v_0_adam10_mouse RummaGEO Gene Perturbation Signatures 1.0 null NF-21-HQ00_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.203123 PMC11925450-elife-96850-supp2.xlsx-DNMT1_KO_vs_DNMT1_L1TD1_dKO_res-geneName_DNMT1 Rummagene Transcription Factor Associations 2026 1.0 null PMC9974104-jci-133-159940-s017.xlsx-GT3-INCP-GATA3_Co-down-Gene_ID_GATA3 Rummagene Transcription Factor Associations 2026 1.0 null GSE203308_14_v_5_brf1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE114013,GSE114014_1_v_3_itraconazole_human RummaGEO Drug Perturbation Signatures -1.0 null GSE148692,GSE148695_5_v_3_satb2_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC9407616__F9 PFOCR Pathway Figure Associations 2024 1.0 null GSE169205_0_v_8_sirt5_human RummaGEO Gene Perturbation Signatures -1.0 null GSE216043_11_v_5_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null GSE241036_4_v_2_ethanol_mouse RummaGEO Drug Perturbation Signatures 1.0 null EE-98-PF86_0.01uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.20797 CHD4-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO ChEA Transcription Factor Targets 2022 1.0 null GSE124048,GSE124067_1_v_0_irf6_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE92965_0_v_1_klf2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE121866_0_v_2_six4_human RummaGEO Gene Perturbation Signatures -1.0 null Hematopoietic system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.043 OF-05-CB18_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.690566 PMC9218776-ADVS-9-2104640-s002.xlsx-SIM_-_Nurr1-Nurr1_modulation_mediates_neuroprotective_effects_of_statins_SIM2 Rummagene Transcription Factor Associations 2026 1.0 null PSEN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.37579 GSE152441,GSE152442_7_v_5_folic acid_human RummaGEO Drug Perturbation Signatures 1.0 null GSE148692,GSE148695_2_v_3_satb2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE165636_0_v_4_tofacitinib_human RummaGEO Drug Perturbation Signatures 1.0 null GSE203158_0_v_8_aire_mouse RummaGEO Gene Perturbation Signatures 1.0 null MAP4K3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95208 GSE84922,GSE84924_4_v_1_sall4_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE62843,GSE64371_2_v_0_furan_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE163275_1_v_0_irf8_human RummaGEO Gene Perturbation Signatures -1.0 null GSE159678_4_v_7_chloroquine_human RummaGEO Drug Perturbation Signatures -1.0 null CDC123 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75528 ZNF654 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.0446 NOB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9819 POMGNT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.21545 GSE211126_1_v_0_hapln1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE126463_0_v_2_arid2_human RummaGEO Gene Perturbation Signatures -1.0 null GSE157594_6_v_7_nicotinamide_mouse RummaGEO Drug Perturbation Signatures -1.0 null IC-28-HS37_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.90783 Esrrg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 37.934 GSE185519_4_v_7_gilteritinib_human RummaGEO Drug Perturbation Signatures 1.0 null GSE151412_2_v_1_sorafenib_human RummaGEO Drug Perturbation Signatures -1.0 null UF-27-HS98_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.342418 Body mass index GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.739794 Adrenal Gland GTEx Tissue Gene Expression Profiles 2023 -1.0 -0.71738 YA-92-YO01_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.14248 PMC5651844-41467_2017_1173_MOESM4_ESM.xlsx-sheet_1-Supplementary_Data_1_Down_regulated_genes_in_YEATS2_KD_cells_AR Rummagene Transcription Factor Associations 2026 1.0 null ETV5::FIGLA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 65.2689 EOMES JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.6914 GSE150049_2_v_0_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null Immune system cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.043 FF-28-ES17_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.35633 Ppara JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.142 GSE126463_5_v_2_pomalidomide_human RummaGEO Drug Perturbation Signatures -1.0 null 496100651_FWM_probable Alzheimer's disease_TBI_83_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -4.08804 GSE146840,GSE146842_3_v_2_qrich1_human RummaGEO Gene Perturbation Signatures -1.0 null GSE206226_0_v_3_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null GSE107505_1_v_2_nanog_mouse RummaGEO Gene Perturbation Signatures 1.0 null SE-15-AV21_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.36726 GA-47-MH68_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.293926 HEY1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.2021 AB-71-CI37_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.31341 GSE139016_3_v_1_disulfiram_human RummaGEO Drug Perturbation Signatures -1.0 null IC-76-JU42_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.74252 496100608_FWM_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.46717 GSE126463_6_v_2_pomalidomide_human RummaGEO Drug Perturbation Signatures -1.0 null abnormal lipid level MGI Mouse Phenotype Associations 2023 1.0 null PMC8047323-Table_1.xlsx-FC_LPS_T24_Vs_LPS_T0_P_0_05_FC-GeneSymbol_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null 496100416_FWM_dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.8451 GSE81803,GSE81912_0_v_1_fmr1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE153189_2_v_3_interferon gamma_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE219195_1_v_5_rbm12_human RummaGEO Gene Perturbation Signatures 1.0 null FDPS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.1304 496100412_FWM_possible Alzheimer's disease_TBI_87_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.71341 GSE242199_9_v_7_ntrk2_human RummaGEO Gene Perturbation Signatures -1.0 null ZSCAN31 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.6563 GSE210990,GSE211030_3_v_2_kmt2d_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE216538_1_v_3_mrs2_mouse RummaGEO Gene Perturbation Signatures 1.0 null XC-81-LR46_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.868333 GSE216273,GSE216292_14_v_7_palbociclib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE233679_6_v_2_nicotinamide_human RummaGEO Drug Perturbation Signatures 1.0 null GB-57-XV52_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.82477 GSE210842_3_v_1_hnf4a_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC8497824-Table_4.xlsx-Stage_4_EOMES_vs_Ctrl-Unnamed_1_EOMES Rummagene Transcription Factor Associations 2026 1.0 null RSPO4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61179 GSE142210_4_v_0_panobinostat_human RummaGEO Drug Perturbation Signatures 1.0 null chr1_2574790_T_C_b38 GTEx eQTL 2025 1.0 1.88946 GSE198165,GSE198166_8_v_2_zfp266_mouse RummaGEO Gene Perturbation Signatures 1.0 null PINX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02508 GSE225901_2_v_1_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null GB-73-QS80_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.359239 GSE162892_4_v_0_isox_human RummaGEO Drug Perturbation Signatures 1.0 null GSE221539_1_v_3_lrrc10_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE203158_1_v_15_aire_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE238116_3_v_2_egr1_human RummaGEO Gene Perturbation Signatures 1.0 null Hematopoietic system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GA-88-CF36_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.15175 ZFP57 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.359 GSE256181_1_v_0_etv2_human RummaGEO Gene Perturbation Signatures -1.0 null GSE140965_1_v_4_mybpc3_human RummaGEO Gene Perturbation Signatures 1.0 null Esophagus - Muscularis GTEx Tissue Gene Expression Profiles 2023 -1.0 -0.826834 Gastrointestinal system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.923 WC-09-GD62_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -2.04864 HAND2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA ChEA Transcription Factor Targets 2022 1.0 null EA-39-YN88_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -3.84273 PMC9978772-Table_2.XLSX-MSC-Gene_ID_MSC Rummagene Transcription Factor Associations 2026 1.0 null GSE151612_4_v_7_pracinostat_human RummaGEO Drug Perturbation Signatures 1.0 null GSE162739_4_v_1_bap1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE173201_0_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null AB-64-ZX70_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.40448 GSE116810_2_v_3_selinexor_human RummaGEO Drug Perturbation Signatures -1.0 null Basal ganglion TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.297 Lymphoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.043 GSE129725_4_v_0_bmal1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE182181_1_v_0_ricolinostat_human RummaGEO Drug Perturbation Signatures 1.0 null PMC11067031-pnas.2317690121.sd05.xlsx-Sheet1-Differentially_expressed_genes_between_PML_RARA_GFP_vs_Empty_vector_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA Rummagene Transcription Factor Associations 2026 1.0 null PMC12238561-42003_2025_8460_MOESM2_ESM.xlsx-IDs_S12_LF_C1_8h-Unnamed_5_LTF Rummagene Transcription Factor Associations 2026 1.0 null GSE135705_5_v_3_corticosterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE233647_2_v_0_docetaxel_human RummaGEO Drug Perturbation Signatures -1.0 null GSE143782_3_v_11_calcitriol_human RummaGEO Drug Perturbation Signatures -1.0 null GSE92457_7_v_8_ethanol_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE158834_12_v_9_palm_human RummaGEO Gene Perturbation Signatures -1.0 null Neck TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 NUMBL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76568 prostaglandin F synthase activity GO Molecular Function Annotations 2025 1.0 null GSE211989_3_v_2_nlrc3_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE176008_4_v_1_azacitidine_human RummaGEO Drug Perturbation Signatures -1.0 null GSE166308_1_v_0_pim1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE163240_3_v_4_enzalutamide_human RummaGEO Drug Perturbation Signatures -1.0 null PMC12774775-mmc2.xlsx-PAR_RARG_merge_q5_Narrow_subKO-Gene_Symbol_RARG Rummagene Transcription Factor Associations 2026 1.0 null prostaglandin metabolic process GO Biological Process Annotations 2025 1.0 null DA-35-DU85_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.281234 ZNF682 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.0974 GSE239688_4_v_3_canagliflozin_human RummaGEO Drug Perturbation Signatures -1.0 null TSPYL4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10896 GSE216273,GSE216292_14_v_6_palbociclib_human RummaGEO Drug Perturbation Signatures -1.0 null Blood cancer cell TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 PD-05-HV36_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.232844 PMC11551338-pnas.2411189121.sd01.xlsx-AHR-Unnamed_0_AHR Rummagene Transcription Factor Associations 2026 1.0 null GSE100528_1_v_0_mettl3_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE125219,GSE125221_4_v_0_arid1a_human RummaGEO Gene Perturbation Signatures -1.0 null GSE149366_1_v_0_sulconazole_human RummaGEO Drug Perturbation Signatures 1.0 null GSE130396_7_v_6_braf_human RummaGEO Gene Perturbation Signatures -1.0 null GSE140322_0_v_1_imatinib_human RummaGEO Drug Perturbation Signatures 1.0 null RHBDF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.01663 Rxra JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 44.8452 GSE206342_1_v_0_kpna2_human RummaGEO Gene Perturbation Signatures -1.0 null GSE117643_1_v_0_irx5_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE138815,GSE138817_0_v_2_kdm6a_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE119498_0_v_7_setd5_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE242199_2_v_0_ntrk2_human RummaGEO Gene Perturbation Signatures -1.0 null GSE205913_1_v_0_palmitic acid_human RummaGEO Drug Perturbation Signatures -1.0 null IA-27-CK10_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.26973 PMC11003700-pbio.3002240.s013.xlsx-siMYCN_RNA_IMR32_48h_q_0_05_1_5-Table_S6_Genes_commonly_and_differentially_regulated_by_MYCN_and_WDR5_in_IMR32_cells_MYCN Rummagene Transcription Factor Associations 2026 1.0 null GSE148066,GSE157787_8_v_6_n4bp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null RSF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.78057 GSE214514_1_v_7_bmal1_mouse RummaGEO Gene Perturbation Signatures 1.0 null STX17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37456 REST JASPAR Predicted Human Transcription Factor Targets 2025 1.0 77.3667 GSE123372,GSE123373_10_v_2_mecp2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE169356_2_v_4_ivermectin_human RummaGEO Drug Perturbation Signatures -1.0 null 496100484_FWM_no dementia_no TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.24695 PGF2alpha MW Enzyme Metabolite Associations 1.0 null Uterine luminal fluid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.734 GA-59-RW04_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -2.23311 GSE114284_1_v_0_irf1_human RummaGEO Gene Perturbation Signatures 1.0 null GSE71491_0_v_1_cyclophosphamide_mouse RummaGEO Drug Perturbation Signatures 1.0 null B9D1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.05827 GSE188869,GSE188871_1_v_3_kat7_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE216043_10_v_8_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null GSE144796_3_v_0_linagliptin_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE157894_1_v_0_cystine_human RummaGEO Drug Perturbation Signatures 1.0 null CF-87-AS90_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.85131 GSE203158_5_v_15_aire_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE183271_1_v_0_nicotinamide_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE148066,GSE157787_9_v_4_n4bp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_JK_LPS-Unnamed_5_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-1_MYB Rummagene Transcription Factor Associations 2026 1.0 null GSE114258_3_v_0_foxk1_mouse RummaGEO Gene Perturbation Signatures -1.0 null DF-84-RT50_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.946904 BTAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52645 KCNC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38982 GSE139455_7_v_3_stat3_human RummaGEO Gene Perturbation Signatures -1.0 null Olfactory bulb TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.041 GA-88-CF36_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.93574 PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null GSE107956,GSE107957_0_v_1_ythdf2_human RummaGEO Gene Perturbation Signatures -1.0 null GSE131649_4_v_5_hemin_human RummaGEO Drug Perturbation Signatures -1.0 null ETV2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.9266 GSE121824,GSE121826_0_v_8_scaf8_human RummaGEO Gene Perturbation Signatures 1.0 null Primary biliary cholangitis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.327 GSE105173,GSE105175_1_v_0_dhx36_human RummaGEO Gene Perturbation Signatures 1.0 null GSE199660_1_v_0_secretin_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE120612_7_v_2_etoposide_human RummaGEO Drug Perturbation Signatures -1.0 null Tumor necrosis factor receptor superfamily complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.838 GSE152441,GSE152442_1_v_2_folic acid_human RummaGEO Drug Perturbation Signatures 1.0 null GSE173405_3_v_0_dmba_mouse RummaGEO Drug Perturbation Signatures -1.0 null PMC10641274-mmc2.xlsx-FOXK1_Insulin-SYMBOL_FOXK1 Rummagene Transcription Factor Associations 2026 1.0 null GSE202434,GSE202438_10_v_1_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE149621_3_v_1_olaparib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE131887_1_v_4_doxycycline_mouse RummaGEO Drug Perturbation Signatures 1.0 null GA-28-SS67_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.392864 GSE114258_3_v_2_foxk1_mouse RummaGEO Gene Perturbation Signatures 1.0 null ARMC5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.33427 Central nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 KMT2D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.357 GSE126463_5_v_3_pomalidomide_human RummaGEO Drug Perturbation Signatures -1.0 null PMC10115638-41591_2023_2255_MOESM4_ESM.xlsx-CNS_NB_FOXR2_deletions-Unnamed_2_FOXR2 Rummagene Transcription Factor Associations 2026 1.0 null MAML2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.26449 GSE211126_3_v_0_hapln1_mouse RummaGEO Gene Perturbation Signatures -1.0 null 496100345_FWM_no dementia_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.20195 OB-06-WW76_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.540775 GSE229973_4_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null IF-87-AU84_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -3.86075 Conceptus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.853 GSE189653,GSE203344_2_v_0_fluoxetine_mouse RummaGEO Drug Perturbation Signatures 1.0 null corl279 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.236 GSE131649_4_v_0_hemin_human RummaGEO Drug Perturbation Signatures -1.0 null psn1 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.569 GSE157894_2_v_0_cystine_human RummaGEO Drug Perturbation Signatures 1.0 null GSE44157,GSE44163_3_v_0_nr6a1_mouse RummaGEO Gene Perturbation Signatures -1.0 null NUBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.78174 GSE63048_11_v_6_morc1_mouse RummaGEO Gene Perturbation Signatures -1.0 null UQCRB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.18995 496100376_FWM_probable Alzheimer's disease_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.08915 HC-92-HE59_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.349525 MED6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.00898 GSE148321,GSE169423_2_v_1_palmitic acid_human RummaGEO Drug Perturbation Signatures -1.0 null PMC6172843-13059_2018_1523_MOESM6_ESM.xls-Sheet1-Table_S5_mRNAs_variation_abundance_1_5-fold_in_YBX1-knockdown_BGC-823_cells_YBX1 Rummagene Transcription Factor Associations 2026 1.0 null GSE203485_1_v_0_sunitinib_human RummaGEO Drug Perturbation Signatures 1.0 null Pparg::Rxra JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 43.3216 GSE203308_7_v_5_brf1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE228162_2_v_5_nr2f6_mouse RummaGEO Gene Perturbation Signatures -1.0 null WC-09-GD62_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.47943 PMC9360325-DataSheet_3.xlsx-DEGs_DLPSvsMLPS_71UP-Data_file_S3C_Upregulated_DEGs_in_DCATH-2_trained_LPS-stimulated_dTHP-1_cells_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null Autoimmune disease of gastrointestinal tract DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.923 MUC3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.25305 GSE95077_5_v_2_amiloride_human RummaGEO Drug Perturbation Signatures -1.0 null GSE160442,GSE160444_1_v_0_arid1a_human RummaGEO Gene Perturbation Signatures -1.0 null Uterine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.803 Colon - Sigmoid GTEx Tissue Gene Expression Profiles 2023 -1.0 -1.52079 T-lymphocyte TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.155 Respiratory allergy DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.674 GSE127790_5_v_2_zcchc8_mouse RummaGEO Gene Perturbation Signatures -1.0 null PXYLP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28738 GSE103068_5_v_3_volasertib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE148692,GSE148695_7_v_0_satb2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE114284_2_v_0_irf1_human RummaGEO Gene Perturbation Signatures 1.0 null GSE232786_1_v_0_otud1_human RummaGEO Gene Perturbation Signatures 1.0 null GSE239688_4_v_0_canagliflozin_human RummaGEO Drug Perturbation Signatures 1.0 null GSE133763_0_v_2_chd1_human RummaGEO Gene Perturbation Signatures -1.0 null GSE223908,GSE223909_1_v_6_serpinb3_human RummaGEO Gene Perturbation Signatures 1.0 null 496100562_FWM_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.48049 GSE95386_0_v_1_trim24_human RummaGEO Gene Perturbation Signatures -1.0 null BC-01-JL64_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.565827 CE-15-YU05_0.01uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.265396 PMC6683136-41598_2019_47363_MOESM5_ESM.xlsx-GENE_SET-Negative_correlation_of_ZEB1_and_other_genes_ZEB1 Rummagene Transcription Factor Associations 2026 1.0 null GSE239688_4_v_1_canagliflozin_human RummaGEO Drug Perturbation Signatures -1.0 null QE-79-XO29_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.665178 NR4A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.02372 GSE70935_2_v_4_cyfip1_human RummaGEO Gene Perturbation Signatures -1.0 null GLIS2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 64.8987 GSE202434,GSE202438_3_v_0_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null FERD3L JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.2423 GSE223908,GSE223909_1_v_3_serpinb3_human RummaGEO Gene Perturbation Signatures 1.0 null FA-80-DR66_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.570043 GSE213588_8_v_6_trametinib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE229973_3_v_0_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null QE-79-XO29_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.910482 Prefrontal cortex TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.16 GSE158431_2_v_0_pioglitazone_mouse RummaGEO Drug Perturbation Signatures 1.0 null DC-51-WE27_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.377234 GSE221742,GSE221743_1_v_2_sipa1_human RummaGEO Gene Perturbation Signatures -1.0 null GSE160817_3_v_1_slamf6_human RummaGEO Gene Perturbation Signatures -1.0 null DF-00-BU08_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.496624 GSE183271_5_v_0_nicotinamide_mouse RummaGEO Drug Perturbation Signatures -1.0 null QE-79-XO29_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.417114 GSE131649_4_v_3_hemin_human RummaGEO Drug Perturbation Signatures -1.0 null SNAP23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.00846 FB-66-UU47_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.44233 GSE235550_1_v_0_hspa9_human RummaGEO Gene Perturbation Signatures 1.0 null non-Hodgkin lymphoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.043 PMC4770763__F3 PFOCR Pathway Figure Associations 2023 1.0 null KC-48-OO62_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.80882 GSE97278,GSE97280_2_v_3_nsd2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Skin - Not Sun Exposed (Suprapubic) GTEx Tissue Gene Expression Profiles 2023 1.0 2.94648 GSE169205_0_v_6_sirt5_human RummaGEO Gene Perturbation Signatures -1.0 null GSE233679_5_v_15_nicotinamide_human RummaGEO Drug Perturbation Signatures -1.0 null GSE115542_5_v_3_digoxin_human RummaGEO Drug Perturbation Signatures -1.0 null GSE151412_2_v_3_sorafenib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE159678_4_v_2_chloroquine_human RummaGEO Drug Perturbation Signatures -1.0 null GSE148262,GSE150691_1_v_2_hdlbp_human RummaGEO Gene Perturbation Signatures -1.0 null GSE101527_0_v_1_smad4_mouse RummaGEO Gene Perturbation Signatures 1.0 null CD-05-PU90_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.211227 MF-11-EW49_0.01uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.229071 ZBTB33 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.4993 Inflammatory bowel disease GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.609691 PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-Partitions_EPC1-PHF1-FLAG-Unnamed_19_PHF1 Rummagene Transcription Factor Associations 2026 1.0 null GSE164508_1_v_0_bortezomib_mouse RummaGEO Drug Perturbation Signatures -1.0 null WC-09-GD62_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -3.79828 GSE178714_3_v_2_smad2_human RummaGEO Gene Perturbation Signatures 1.0 null Serotonergic synapse COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.152 PMC11185762-media-2.xlsx-ATAC2wk_KD_V337M_intersect_peak-Symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null EA-18-FP00_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.6197 ALDH7A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.52547 Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.184 GSE160817_0_v_8_slamf6_human RummaGEO Gene Perturbation Signatures 1.0 null Liver cirrhosis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.327 GSE122101,GSE122103_3_v_4_ssu72_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC11908325-media-2.xlsx-Table10_MR-Unnamed_2_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null GSE114284_2_v_3_irf1_human RummaGEO Gene Perturbation Signatures 1.0 null APLNR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.0064 BD-98-XW77_0.01uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.222098 GSE116810_5_v_0_selinexor_human RummaGEO Drug Perturbation Signatures 1.0 null GSE249404_0_v_1_oxytocin_human RummaGEO Drug Perturbation Signatures -1.0 null GSE148692,GSE148695_2_v_4_satb2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE92614_1_v_0_pten_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE176008_8_v_1_azacitidine_human RummaGEO Drug Perturbation Signatures -1.0 null PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-MECP2-toNode_MECP2 Rummagene Transcription Factor Associations 2026 1.0 null GSE228106_3_v_2_paclitaxel_human RummaGEO Drug Perturbation Signatures -1.0 null GSE189653,GSE203344_5_v_3_fluoxetine_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE129389_0_v_6_tropifexor_mouse RummaGEO Drug Perturbation Signatures -1.0 null AE-85-LR48_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.280249 KA-75-LP02_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.269206 GSE125219,GSE125221_4_v_2_arid1a_human RummaGEO Gene Perturbation Signatures -1.0 null ETV2::FIGLA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.1116 GSE184356_1_v_2_tfam_human RummaGEO Gene Perturbation Signatures -1.0 null WE-43-PZ45_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.668198 Tongue epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.757 MYOG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.7323 FE-49-VJ28_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.206337 GSE104022_1_v_0_tamoxifen_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE135514_8_v_0_dasatinib_human RummaGEO Drug Perturbation Signatures -1.0 null EXOC8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.51413 PB-09-OE00_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.376445 AD-51-SS86_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.725047 GSE144838_2_v_5_egfr_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_U87MG_KD-geneSymbol_AR Rummagene Transcription Factor Associations 2026 1.0 null tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GSE157594_3_v_7_nicotinamide_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE81803,GSE81912_0_v_5_fmr1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Pod TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.519 MYOD1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.8355 GSE148066,GSE157787_9_v_7_n4bp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Organ system cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.043 GSE255432_4_v_0_imeglimin_mouse RummaGEO Drug Perturbation Signatures -1.0 null HES2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.778 GSE114258_1_v_2_foxk1_mouse RummaGEO Gene Perturbation Signatures 1.0 null FB-39-CW59_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.949565 GSE125007,GSE125008_5_v_0_uhrf1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE153354_0_v_1_tcf19_human RummaGEO Gene Perturbation Signatures 1.0 null PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Supplementary_Table_2E_Contrast_ATF4-def_Tg_8h_vs_HCT116_Tg_8h_ATF4 Rummagene Transcription Factor Associations 2026 1.0 null TECPR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.06448 GSE122067_3_v_1_mtch2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE126463_0_v_2_pomalidomide_human RummaGEO Drug Perturbation Signatures -1.0 null GSE195503_3_v_0_progesterone_human RummaGEO Drug Perturbation Signatures -1.0 null GSE131887_1_v_0_doxycycline_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE172019_2_v_8_rnf2_human RummaGEO Gene Perturbation Signatures 1.0 null GSE216540_10_v_6_fulvestrant_human RummaGEO Drug Perturbation Signatures -1.0 null AC-35-CK01_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.19786 GSE143499_0_v_1_gata6_human RummaGEO Gene Perturbation Signatures -1.0 null GSE197630_1_v_0_enzalutamide_human RummaGEO Drug Perturbation Signatures -1.0 null ZDHHC19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.74068 GSE70499_4_v_2_bmal1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE120612_7_v_0_etoposide_human RummaGEO Drug Perturbation Signatures -1.0 null Lymphoid tissue TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 CELF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52588 EA-18-FP00_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.00032 PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_A549_KD-geneSymbol_AR Rummagene Transcription Factor Associations 2026 1.0 null NFIX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.3317 GSE114013,GSE114014_1_v_4_itraconazole_human RummaGEO Drug Perturbation Signatures -1.0 null GB-73-QS80_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.451647 GSE152441,GSE152442_6_v_4_folic acid_human RummaGEO Drug Perturbation Signatures -1.0 null LRRC75B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.03988 Gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 PMC8191339-mmc1.xlsx-Table_S3_DE_genes-LPS_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null Nr1h2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.2251 GSE189653,GSE203344_4_v_3_fluoxetine_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE229973_4_v_0_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_A549_KD-GeneID_AR Rummagene Transcription Factor Associations 2026 1.0 null YD-49-HM53_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.897328 GSE57397,GSE57399_1_v_0_fbxw7_human RummaGEO Gene Perturbation Signatures 1.0 null GSE217552_3_v_4_fisetin_human RummaGEO Drug Perturbation Signatures -1.0 null Colitis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.923 PGS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.54551 GSE239688_2_v_5_canagliflozin_human RummaGEO Drug Perturbation Signatures -1.0 null ATAD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36576 GSE213588_8_v_7_trametinib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE230744,GSE237803_0_v_3_hira_human RummaGEO Gene Perturbation Signatures 1.0 null GSE231799_3_v_1_nfkbie_mouse RummaGEO Gene Perturbation Signatures 1.0 null HUPT4_PANCREAS CCLE Cell Line Proteomics 1.0 5.78426 Olfactory lobe TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.041 KLF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 72.7312 PC-62-AQ92_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.276996 GSE151364,GSE151366_1_v_2_taf4_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE188382_4_v_0_sirt5_human RummaGEO Gene Perturbation Signatures 1.0 null MC-40-IP75_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.269019 GSE114883_1_v_2_romidepsin_human RummaGEO Drug Perturbation Signatures 1.0 null GSE203158_0_v_14_aire_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-7_MYB Rummagene Transcription Factor Associations 2026 1.0 null GSE223008_6_v_8_calhm6_mouse RummaGEO Gene Perturbation Signatures -1.0 null t61-colon_consensus MoTrPAC Rat Endurance Exercise Training 1.0 4.05431 GSE62843,GSE64371_2_v_5_furan_mouse RummaGEO Drug Perturbation Signatures -1.0 null FOXE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.51996 GSE162739_6_v_1_bap1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE173307,GSE173391_0_v_1_rgcc_human RummaGEO Gene Perturbation Signatures -1.0 null FC-13-VS25_0.01uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.533086 GSE130396_1_v_6_neratinib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE196117_6_v_11_clarithromycin_human RummaGEO Drug Perturbation Signatures -1.0 null DF-45-GA42_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.241907 GSE201239_3_v_2_fmr1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE100316_3_v_6_mtor_mouse RummaGEO Gene Perturbation Signatures 1.0 null PFKFB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.2148 GSE203072_2_v_3_rpl3l_mouse RummaGEO Gene Perturbation Signatures 1.0 null Ulcerative colitis GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.0 GSE217132_0_v_1_pfkfb4_human RummaGEO Gene Perturbation Signatures -1.0 null FB-66-UU47_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.782881 GSE57871_5_v_2_vorinostat_human RummaGEO Drug Perturbation Signatures 1.0 null TFEC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.4963 Medulla oblongata TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.041 GSE203158_12_v_15_aire_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE234289_4_v_2_rfx6_human RummaGEO Gene Perturbation Signatures 1.0 null GSE233647_4_v_5_docetaxel_human RummaGEO Drug Perturbation Signatures -1.0 null PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCall_EPC1-PHF1_FLAG_K562-ENSEMBL_PHF1 Rummagene Transcription Factor Associations 2026 1.0 null ZBTB7B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 52.5017 FC-85-OX77_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.81447 GSE198165,GSE198166_9_v_4_zfp266_mouse RummaGEO Gene Perturbation Signatures 1.0 null Brain TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GSE227127_1_v_0_diclofenac_human RummaGEO Drug Perturbation Signatures -1.0 null PLPP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.51489 GSE142210_11_v_10_panobinostat_human RummaGEO Drug Perturbation Signatures -1.0 null GSE148252_5_v_4_npas4_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE146982_7_v_5_metformin_human RummaGEO Drug Perturbation Signatures 1.0 null Celiac disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.78 GSE110268_0_v_3_foxd1_human RummaGEO Gene Perturbation Signatures -1.0 null GSE152441,GSE152442_0_v_4_folic acid_human RummaGEO Drug Perturbation Signatures -1.0 null PMC12240782-Table3.xlsx-Sheet1-E2F1_E2F1 Rummagene Transcription Factor Associations 2026 1.0 null PMC10185556-41467_2023_38439_MOESM3_ESM.xlsx-ST12_cg_gene_assoc_visc_TAD-target_ensembl_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null GSE127790_9_v_2_zcchc8_mouse RummaGEO Gene Perturbation Signatures -1.0 null 496100346_FWM_no dementia_TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.44431 GSE193258,GSE193259_2_v_8_osimertinib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE216273,GSE216292_14_v_1_palbociclib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE119694_1_v_0_lifr_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE171837_0_v_3_bortezomib_human RummaGEO Drug Perturbation Signatures 1.0 null PMC6879499__F3 PFOCR Pathway Figure Associations 2023 1.0 null ZNF343 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 62.2634 GSE223008_9_v_8_calhm6_mouse RummaGEO Gene Perturbation Signatures -1.0 null Avian pallium TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.297 PET100 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.10244 GSE140937,GSE140938_0_v_2_slfn11_human RummaGEO Gene Perturbation Signatures 1.0 null GSE255432_4_v_3_imeglimin_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE62843,GSE64371_4_v_0_furan_mouse RummaGEO Drug Perturbation Signatures 1.0 null CB-24-FA25_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.308458 NF-21-HQ00_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.627824 LE-40-JW92_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.828566 Neostriatum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.002 GSE213588_8_v_13_trametinib_human RummaGEO Drug Perturbation Signatures -1.0 null Large B-cell lymphoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.043 GSE239688_2_v_3_canagliflozin_human RummaGEO Drug Perturbation Signatures -1.0 null GSE57871_6_v_2_vorinostat_human RummaGEO Drug Perturbation Signatures 1.0 null GSE84148,GSE96938_0_v_2_nrros_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE92364_0_v_5_asparaginase_mouse RummaGEO Drug Perturbation Signatures -1.0 null Testicular cancer cell TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GB-57-XV52_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.62304 GSE199660_1_v_3_secretin_mouse RummaGEO Drug Perturbation Signatures -1.0 null PMC11568168-41598_2024_79607_MOESM3_ESM.xls-11-E2F1_E2F1 Rummagene Transcription Factor Associations 2026 1.0 null Cells - EBV-transformed lymphocytes GTEx Tissue Gene Expression Profiles 2023 -1.0 -1.15406 AAR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.00103 ocular hypertension MGI Mouse Phenotype Associations 2023 1.0 null Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.202 PMC12513837-41588_2025_2336_MOESM4_ESM.xlsx-Supplementary_Table_1-Supplementary_Table_1_List_of_AR-only_and_p300_AR-shared_enhancer_regulated_genes_AR Rummagene Transcription Factor Associations 2026 1.0 null KLF5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 112.646 PRELID3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01003 GSE131649_6_v_3_hemin_human RummaGEO Drug Perturbation Signatures -1.0 null GSE135514_2_v_6_dasatinib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE147876,GSE147877_4_v_7_enzalutamide_human RummaGEO Drug Perturbation Signatures -1.0 null GSE226249_5_v_8_pirfenidone_human RummaGEO Drug Perturbation Signatures -1.0 null GSE189653,GSE203344_2_v_1_fluoxetine_mouse RummaGEO Drug Perturbation Signatures 1.0 null Cervical canal TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.504 GSE111102,GSE111105_3_v_0_pparg_mouse RummaGEO Gene Perturbation Signatures -1.0 null IFNGR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.66474 GSE168596_1_v_3_adiponectin_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE215086_5_v_6_batf_human RummaGEO Gene Perturbation Signatures -1.0 null GSE154936_3_v_2_remdesivir_human RummaGEO Drug Perturbation Signatures -1.0 null GSE196407_1_v_0_fluorouracil_mouse RummaGEO Drug Perturbation Signatures -1.0 null E2F4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.9111 Fallopian Tube GTEx Tissue Gene Expression Profiles 2023 1.0 2.75691 GSE229344_2_v_0_cyb5r3_human RummaGEO Gene Perturbation Signatures -1.0 null Dopaminergic synapse COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.71 GSE228106_3_v_4_paclitaxel_human RummaGEO Drug Perturbation Signatures -1.0 null PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCall_EPC1-PHF1_FLAG_K562-SYMBOL_PHF1 Rummagene Transcription Factor Associations 2026 1.0 null GSE242083,GSE242098_2_v_4_med1_human RummaGEO Gene Perturbation Signatures 1.0 null AD-66-NV75_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.21378 GSE135514_8_v_6_dasatinib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE130676_0_v_1_suds3_human RummaGEO Gene Perturbation Signatures 1.0 null GSE228106_3_v_5_paclitaxel_human RummaGEO Drug Perturbation Signatures -1.0 null PMC5637904-PATH-243-193-s016.xlsx-human_down_in_fat_SOX11-Unnamed_7_SOX11 Rummagene Transcription Factor Associations 2026 1.0 null ZIC4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 84.5109 Connective tissue disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.902 GSE190384,GSE190386_1_v_8_fulvestrant_human RummaGEO Drug Perturbation Signatures -1.0 null GSE221932,GSE222115_0_v_1_ezh2_human RummaGEO Gene Perturbation Signatures -1.0 null 496100554_FWM_no dementia_no TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.00788 PMC7880998-41467_2021_21255_MOESM8_ESM.xlsx-Sup_Data_5_TWIST_Panel-Gene_Name_TWIST1 Rummagene Transcription Factor Associations 2026 1.0 null SB-87-LQ34_0.01uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.257658 GSE122215,GSE122217_0_v_1_peg10_mouse RummaGEO Gene Perturbation Signatures -1.0 null OC-71-BZ81_0.01uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.249165 Thorax TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GSE122990,GSE123061_0_v_1_urod_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE223008_5_v_3_calhm6_mouse RummaGEO Gene Perturbation Signatures 1.0 null Nr1h3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 27.2046 GSE164757,GSE164759_1_v_3_trametinib_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE209598_0_v_3_tgfbr2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE216043_11_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null HN cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.821 GSE145445,GSE145454_0_v_1_cop1_mouse RummaGEO Gene Perturbation Signatures 1.0 null KLF6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 48.2967 AE-19-BK71_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.270889 GC-69-JF03_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.258342 GSE148252_1_v_4_npas4_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE102486,GSE102490_1_v_5_setdb1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE199874_4_v_5_gabpb1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE201309_5_v_0_matrine_human RummaGEO Drug Perturbation Signatures -1.0 null PMC11825621-210_2024_3353_MOESM2_ESM.xlsx-AR-IL13_AR Rummagene Transcription Factor Associations 2026 1.0 null ZBTB24 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 80.872 GSE167984,GSE167987_0_v_1_setd1b_mouse RummaGEO Gene Perturbation Signatures 1.0 null PRC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.64775 FB-66-UU47_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -2.25396 HC-74-HM63_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.941837 GSE141726,GSE141733_1_v_0_angiotensin ii_mouse RummaGEO Drug Perturbation Signatures 1.0 null RMDN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36168 GSE203158_5_v_8_aire_mouse RummaGEO Gene Perturbation Signatures -1.0 null ZNF549 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 47.8135 GSE48812_8_v_5_sulforaphane_human RummaGEO Drug Perturbation Signatures 1.0 null GSE130396_7_v_6_neratinib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE96641_5_v_2_esrp2_mouse RummaGEO Gene Perturbation Signatures 1.0 null DA-35-DU85_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.739517 GSE233679_12_v_4_nicotinamide_human RummaGEO Drug Perturbation Signatures 1.0 null COPS6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45468 AB-09-EA37_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.480498 GSE137702_2_v_1_selinexor_human RummaGEO Drug Perturbation Signatures 1.0 null GSE195559_0_v_9_notch1_human RummaGEO Gene Perturbation Signatures -1.0 null PMC9013128-NIHMS1795992-supplement-4.xlsx-SKmel147_ARID2_KO_Downregulated-Gene_name_ARID2 Rummagene Transcription Factor Associations 2026 1.0 null GSE189609_1_v_2_hax1_human RummaGEO Gene Perturbation Signatures 1.0 null BB-20-UU03_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.680305 EBF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 57.5192 SLC17A7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.0172 TBX2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA ChEA Transcription Factor Targets 2022 1.0 null GSE76425_0_v_10_lenalidomide_human RummaGEO Drug Perturbation Signatures -1.0 null GSE131649_2_v_9_hemin_human RummaGEO Drug Perturbation Signatures -1.0 null PMC8635809-Table_2.xls-LPS-downregulated-Unnamed_4_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null GSE169356_2_v_3_ivermectin_human RummaGEO Drug Perturbation Signatures -1.0 null PMC9108619-EMBJ-41-e109191-s016.xlsx-UPF3A_KO_14_3B_KD-gene_name_AR Rummagene Transcription Factor Associations 2026 1.0 null GSE96641_1_v_2_esrp2_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC9195629-Table1.xlsx-Supplementary_Table_1-JUN_JUN Rummagene Transcription Factor Associations 2026 1.0 null PMC5993422-NIHMS922534-supplement-Sup_Tables_1-23.xlsx-RELA-EnhancerAssociatedGene-Unnamed_3_RELA Rummagene Transcription Factor Associations 2026 1.0 null GSE145915_3_v_2_pcm1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Endometritis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.335 Cortical collecting duct cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.527 PMC11639743-mmc2.xlsx-LIN28B-gene_name_LIN28B Rummagene Transcription Factor Associations 2026 1.0 null UTP25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.012 GSE169205_3_v_6_sirt5_human RummaGEO Gene Perturbation Signatures -1.0 null HC-74-HM63_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.480996 FAM118A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54392 GSE242199_9_v_0_ntrk2_human RummaGEO Gene Perturbation Signatures -1.0 null PMC9336541-Table_3.XLSX-C-vs-H6-L_filter_annot-Unnamed_18_HMX1 Rummagene Transcription Factor Associations 2026 1.0 null PMC11551338-pnas.2411189121.sd01.xlsx-FXR-Unnamed_0_NR1H4 Rummagene Transcription Factor Associations 2026 1.0 null GSE142210_2_v_8_panobinostat_human RummaGEO Drug Perturbation Signatures 1.0 null GSE60837_0_v_4_bcl9_mouse RummaGEO Gene Perturbation Signatures 1.0 null FF-86-NH56_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.338777 Bone marrow cancer cell TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO Molecular Function Annotations 2023 1.0 null Nr5a1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.7501 DCAF13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.24492 GSE143782_3_v_4_calcitriol_human RummaGEO Drug Perturbation Signatures -1.0 null PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-8_MYB Rummagene Transcription Factor Associations 2026 1.0 null Hematologic cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.043 GF-35-IT27_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.22942 Epididymis TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 ERF::FIGLA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.0677 GSE198165,GSE198166_8_v_4_zfp266_mouse RummaGEO Gene Perturbation Signatures 1.0 null FAM174C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.0299 GSE138672_4_v_3_rabgef1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Pituitary GTEx Tissue Gene Expression Profiles 2023 1.0 1.58904 GSE85880,GSE85881_0_v_1_tretinoin_human RummaGEO Drug Perturbation Signatures 1.0 null Myelin sheath COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 GSE233679_5_v_1_nicotinamide_human RummaGEO Drug Perturbation Signatures -1.0 null GSE185519_3_v_0_gilteritinib_human RummaGEO Drug Perturbation Signatures 1.0 null GSE216043_10_v_9_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null GSE165071,GSE165072_1_v_0_dexamethasone_mouse RummaGEO Drug Perturbation Signatures -1.0 null PMC8812561-pnas.2110428119.sd11.xlsx-Sheet1-The_overlapping_genes_of_LCDR_KD_RNA-seq_hnRNP_K_KD_RNA-seq_hnRNP_K_RIP-seq_and_eCLIP-seq_AR Rummagene Transcription Factor Associations 2026 1.0 null PMC11625982-AJH-100-10-s001.pdf-28-ZNF680_ZNF680 Rummagene Transcription Factor Associations 2026 1.0 null GSE129287_0_v_1_cd200_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE240645_3_v_2_u90926_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE92965_0_v_1_tamoxifen_mouse RummaGEO Drug Perturbation Signatures -1.0 null PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-4_MYB Rummagene Transcription Factor Associations 2026 1.0 null GSE189941_1_v_2_kdm4c_human RummaGEO Gene Perturbation Signatures 1.0 null GSE206516,GSE206518_1_v_7_ptdss2_human RummaGEO Gene Perturbation Signatures -1.0 null GSE233647_2_v_3_docetaxel_human RummaGEO Drug Perturbation Signatures 1.0 null CB-839 DeepCoverMOA Drug Mechanisms of Action -1.0 -0.34 ARHGAP11B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.50784 GSE215086_0_v_2_batf_human RummaGEO Gene Perturbation Signatures 1.0 null GSE162892_3_v_0_sox9_human RummaGEO Gene Perturbation Signatures 1.0 null ficolin-1-rich granule lumen COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.923 OE-31-YC41_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.18283 HES5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.2019 PMC5105166-ncomms13331-s5.xlsx-Sheet1-Supplementary_Data_4_Gene_expression_signature_of_MEF2D-rearranged_cases_stranded_data_only_MEF2D Rummagene Transcription Factor Associations 2026 1.0 null PMC12103066-FEBS-292-2688-s001.pdf-171-SREBF1_SREBF1 Rummagene Transcription Factor Associations 2026 1.0 null Gli2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.9691 PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-6_MYB Rummagene Transcription Factor Associations 2026 1.0 null GSE131649_2_v_5_hemin_human RummaGEO Drug Perturbation Signatures -1.0 null E2F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.9601 GSE140997_2_v_1_nsun6_human RummaGEO Gene Perturbation Signatures -1.0 null FD-91-OK66_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.227987 AC-74-ZA35_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -3.93241 GSE162892_3_v_2_sox9_human RummaGEO Gene Perturbation Signatures 1.0 null SB-94-ZA83_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.22166 BE-79-QU25_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.15173 GSE203158_0_v_13_aire_mouse RummaGEO Gene Perturbation Signatures 1.0 null NE-94-VE83_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.311004 NFKB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.9088 Bcl11b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.0262 GSE148252_1_v_6_npas4_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE179002_4_v_7_caprin1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE233647_4_v_0_docetaxel_human RummaGEO Drug Perturbation Signatures -1.0 null GA-28-SS67_0.01uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.345803 Embryonic brain TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.0 CF-50-QK79_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.3075 PMC12396377-jcb_202307079_tables1.xlsx-Fig_1C_i_-_iii_left-x_TFEB_KO_con_VS_WT_con_DOWN_TFEB Rummagene Transcription Factor Associations 2026 1.0 null GSE142430_2_v_1_prmt5_human RummaGEO Gene Perturbation Signatures -1.0 null COPS8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.24464 GSE131649_2_v_11_hemin_human RummaGEO Drug Perturbation Signatures -1.0 null BB-20-UU03_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.68691 496100391_FWM_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.47944 KRI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33892 GSE142210_9_v_5_panobinostat_human RummaGEO Drug Perturbation Signatures -1.0 null PMC12478272-mmc1.xlsx-Table_S7-Supplementary_Table_7_Proteome-wide_MR_and_sensitivity_analysis_results_using_the_brain_pQTL_dataset_from_Wingo_et_al_1_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null GSE201239_3_v_4_fmr1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Hepatobiliary disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.592 GSE205630_0_v_1_gmds_human RummaGEO Gene Perturbation Signatures 1.0 null GSE191021_1_v_0_nono_human RummaGEO Gene Perturbation Signatures 1.0 null GSE211983_0_v_3_nicotine_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE142210_9_v_10_panobinostat_human RummaGEO Drug Perturbation Signatures -1.0 null GSE152441,GSE152442_1_v_5_folic acid_human RummaGEO Drug Perturbation Signatures 1.0 null DC-51-WE27_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.431537 GSE180200,GSE180201_3_v_11_qpctl_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE100863,GSE100864_3_v_0_tet2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE160817_7_v_9_slamf6_human RummaGEO Gene Perturbation Signatures 1.0 null GSE175571_3_v_2_acsl6_mouse RummaGEO Gene Perturbation Signatures 1.0 null UC-58-DM11_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.354727 Ibrutinib1 DeepCoverMOA Drug Mechanisms of Action -1.0 -1.1 GSE138938_1_v_3_foxp2_human RummaGEO Gene Perturbation Signatures -1.0 null Sjogren-Larsson syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.094 GSE148066,GSE157787_11_v_7_n4bp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE102505_6_v_3_tunicamycin_human RummaGEO Drug Perturbation Signatures -1.0 null