association dataset threshold value standardized value abnormality of nervous system morphology HPO Gene-Disease Associations 1.0 null abnormality of the nervous system HPO Gene-Disease Associations 1.0 null Congenital Hemivertebra DisGeNET Gene-Disease Associations 1.0 null TBX18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.8523 Calcification Of Falx Cerebri DisGeNET Gene-Disease Associations 1.0 null ZNF814 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.32792 Intestinal schistosomiasis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.186 Cardiac Fibroma DisGeNET Gene-Disease Associations 1.0 null nevoid basal cell carcinoma syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.6256 PMC6761967__F5 PFOCR Pathway Figure Associations 2023 1.0 null abnormality of the mouth HPO Gene-Disease Associations 1.0 null TC205 DepMap CRISPR Gene Dependency 1.0 2.87014 rostral division of OFCi (area 11) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.862203 H1FX Pathway Commons Protein-Protein Interactions 1.0 null hsa-miR-548aj TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 Thoracic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.686 mRNA_POU5F1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null PMC3720582__F2 PFOCR Pathway Figure Associations 2023 1.0 null GSE198165,GSE198166_8_v_10_zfp266_mouse RummaGEO Gene Perturbation Signatures 1.0 null AsPC-1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.82 heart disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.078233 GSE86507,GSE86509_3_v_2_hoxb7_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-OOBK-2126-SM-3LK5T GTEx Tissue Sample Gene Expression Profiles 1.0 1.12721 AGO2_02_132 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 2.22479 ectoderm TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.864734 diethylstilbestrol_mus musculus_gpl81_gds982 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null bifid ribs HPO Gene-Disease Associations 1.0 null Cytoneme COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.29 GSE162739_8_v_1_bap1_mouse RummaGEO Gene Perturbation Signatures 1.0 null HUNS1 CCLE Cell Line Gene Expression Profiles 1.0 1.35106 GTEX-V1D1-0008-SM-4JBIJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.39924 basal cell carcinoma KEGG Pathways 1.0 null GHITM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.49951 Gonadal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.554 GSE133213_2_v_3_znrf3_mouse RummaGEO Gene Perturbation Signatures 1.0 null theca interna TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.211571 Sclerotome TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.245 abnormality of the ocular region HPO Gene-Disease Associations 1.0 null C-33 A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.958706 Brachydactyly DisGeNET Gene-Disease Associations 1.0 null Cell type benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.624 IHH Pathway Commons Protein-Protein Interactions 1.0 null RARS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.93689 Necrosis CTD Gene-Disease Associations 1.0 1.46568 HCC2688 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.959584 HTC-C3 COSMIC Cell Line Gene Mutation Profiles 1.0 null Sporangiophore TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.297 GTEX-PX3G-0008-SM-48U2L GTEx Tissue Sample Gene Expression Profiles -1.0 -1.34758 internal male genital organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.590437 BRD-K84423439 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.09386 regulation of signaling GO Biological Process Annotations 2015 1.0 null GTEX-X638-0003-SM-47JZ1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.09677 EP300_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XXEK-0005-SM-4BRWJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.23566 GIT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.05637 abnormal heart left ventricle morphology MGI Mouse Phenotype Associations 2023 1.0 null NCI-H2170 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01878 ZR-75-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.74203 nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.067056 GSE133070_3_v_1_prss1_mouse RummaGEO Gene Perturbation Signatures -1.0 null SK-MEL-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null TT1TKB DepMap CRISPR Gene Dependency 1.0 2.41213 GTEX-RU72-0006-SM-2TF65 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.873411 CTCF_CH12.LX_mm9_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormal respiratory system morphology GWASdb SNP-Phenotype Associations 1.0 0.152023 Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-5398-01A-02R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SK-MM-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.18371 thyroid_5a HPA Tissue Sample Gene Expression Profiles -1.0 -1.16899 H3K27me3_Penis Foreskin Fibroblast Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE136869_1_v_0_lpar2_mouse RummaGEO Gene Perturbation Signatures 1.0 null PRPF4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.3922 GATA6-21074721-CACO-2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null ovary HPA Tissue Protein Expression Profiles -1.0 -2.29659 NCI-H2171 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.60295 Joubert syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.271 KLF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 81.08 BRD-K12411112 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.09307 GSE219103,GSE219104_0_v_1_progesterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null STIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.30027 DAOY cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.253 GTEX-X4XX-0011-R8B-SM-46MWM GTEx Tissue Sample Gene Expression Profiles 1.0 0.852227 NR2F2_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ARPC5 Pathway Commons Protein-Protein Interactions 1.0 null EWSR1_KD_GDS4962_467_human_not specified GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null MAZ_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormality of the genitourinary system GWASdb SNP-Phenotype Associations 1.0 0.060854 CBX2-22325352-293T-REX-HUMAN ChEA Transcription Factor Targets 2022 1.0 null STK40 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.30891 Rhabdomyosarcoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.996 GTEX-PVOW-2726-SM-48TCA GTEx Tissue Sample Gene Expression Profiles 1.0 1.05921 CRCGN016_MCF10A.TP53.M_24H:H09 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.39568 JUND_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PANC 05.04 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.932825 H3K9ac_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null short digit HPO Gene-Disease Associations 1.0 null GOLGB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.12272 HNRNPH1 Pathway Commons Protein-Protein Interactions 1.0 null hip TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.308251 BRD-K97013733 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.50957 etofenamate-2907 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null WAOSEL DepMap CRISPR Gene Dependency 1.0 2.14841 PMC6078963-41467_2018_5311_MOESM5_ESM.xlsx-48h_KD_UP_Vs_ATAC-Genes_AR Rummagene Transcription Factor Associations 2026 1.0 null PAPLN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.44493 NCI-H3122 COSMIC Cell Line Gene Mutation Profiles 1.0 null SMC3 ENCODE Transcription Factor Targets 1.0 null BRD-K85418917 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.13619 DKC1 Pathway Commons Protein-Protein Interactions 1.0 null paracentral lobule, posterior part, right, bank of cingulate sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.72828 GTEX-T6MO-0006-SM-32QOU GTEx Tissue Sample Gene Expression Profiles -1.0 -2.62062 MDA-MB-175-VII Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.941527 COPS8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18368 BRD-K85722065 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.49627 GSE94849_6_v_4_pinometostat_human RummaGEO Drug Perturbation Signatures 1.0 null CA-72-JV60_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.25151 Fibroepithelial basal cell carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.798 Dorsum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.315 H2BC14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.14611 TGBC11TKB COSMIC Cell Line Gene Mutation Profiles 1.0 null inner CP in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.939786 CTCF_BJ_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Columnar cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.824 colorectal cancer GWASdb SNP-Disease Associations 1.0 0.739121 Lung adenocarcinoma_LUAD_TCGA-53-A4EZ-01A-12R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-OHPL-2426-SM-48TDN GTEx Tissue Sample Gene Expression Profiles 1.0 2.42753 GSE173262_6_v_0_ash1l_mouse RummaGEO Gene Perturbation Signatures 1.0 null POLR2A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RVPV-0006-SM-2TF6Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.05648 MYC-18358816-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Lung cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.619 Piccolo NuA4 histone acetyltransferase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.651 Posterior cardinal vein TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.183 anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.16996 GTEX-U8T8-0426-SM-3DB8X GTEx Tissue Sample Gene Expression Profiles 1.0 0.911054 minoxidil-4800 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null H3K27ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K16891407 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15744 Abnormality Of The Sternum DisGeNET Gene-Phenotype Associations 1.0 null disease of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.042906 FOSL1 ENCODE Transcription Factor Targets 1.0 null Cornified envelope COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.839 H3K4me1_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SAG Pathway Commons Protein-Protein Interactions 1.0 null SG in granular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.926524 BRD-K46308702 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.86733 hsa-miR-603 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 BRD-K44339278 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.11592 BRD-K08241590 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.08977 Musculoskeletal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.817 down-sloping shoulders HPO Gene-Disease Associations 1.0 null smoothened binding GO Molecular Function Annotations 2025 1.0 null H4K20me1_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF-31629814-HEPATOCYTES-MOUSE-TYROSINEMIA ChEA Transcription Factor Targets 2022 1.0 null ATP5A1 Pathway Commons Protein-Protein Interactions 1.0 null Meningioma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.816 CPNE8 Pathway Commons Protein-Protein Interactions 1.0 null Gastrointestinal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.852 PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Unnamed_4_KLF4 Rummagene Transcription Factor Associations 2026 1.0 null MYLK_knockdown_49_GSE14525 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.09192 GTEX-T6MN-0626-SM-32PM9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.03214 GSE169356_2_v_3_ivermectin_human RummaGEO Drug Perturbation Signatures -1.0 null BRD-K07870648 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03655 H3K9ac_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null HSPA7 Pathway Commons Protein-Protein Interactions 1.0 null SAP30 ENCODE Transcription Factor Targets 1.0 null tissue development GO Biological Process Annotations 2015 1.0 null BRD-K62620616 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15035 HCC1187 CCLE Cell Line Gene Mutation Profiles 1.0 null H3K4me3_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null salivarygland BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 Stomach cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.482 Leukemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.532 ZBTB7A_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PWCY-0526-SM-2I3ER GTEx Tissue Sample Gene Expression Profiles -1.0 -0.980326 CTCF-18555785-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null U-937 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.05545 SPINT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.50476 SIN3A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Testis BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.909632 GCT GDSC Cell Line Gene Expression Profiles 1.0 1.43348 BRD-K55238630 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.43627 ZSCAN16 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.3394 PMC12498537-KRNB_A_2569192_SM1642.docx-5-ZNF148_ZNF148 Rummagene Transcription Factor Associations 2026 1.0 null Atf3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.7483 GTEX-WYVS-2426-SM-3NMA9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.89673 Theca cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.252 GTEX-NL4W-0008-SM-4E3I2 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13515 H3K9ac_Stomach Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Holoprosencephaly 7 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.243 SG in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.841657 golgi apparatus LOCATE Predicted Protein Localization Annotations 1.0 null mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.51571 PMC9038526-mmc1.xlsx-healthy_ctr_vs_LPS-symbols_98_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null NCIH1355 CCLE Cell Line Gene Mutation Profiles 1.0 null testis_7b HPA Tissue Sample Gene Expression Profiles 1.0 1.47501 PMC10123531-NIHMS1874945-supplement-Table_S6.xlsx-SOX2_BCAT_cobound_peaks-Gene_Name_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-SIU7-0001-SM-3NMAW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.32568 MST1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.01985 COLO668 CCLE Cell Line Gene CNV Profiles 1.0 1.97365 H3K4me3_GM06990_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lung transplant rejection_Trachea_GSE3418 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.25566 ZNF384_ES-E14_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EBNA1BP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64546 MZ in rostral midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.30965 precommissural nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.41328 HMEC Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -0.921508 GTEX-OIZH-0005-SM-2HMJN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.71307 GTEX-XUJ4-0526-SM-4BOON GTEx Tissue Sample Gene Expression Profiles -1.0 -0.945333 MARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.70712 PA-TU-8988S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.975251 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4988-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null regulation of cellular component organization GO Biological Process Annotations 2025 1.0 null EIF3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38959 GSE244072_10_v_8_tfeb_mouse RummaGEO Gene Perturbation Signatures 1.0 null microphthalmos HPO Gene-Disease Associations 1.0 null YWHAE Pathway Commons Protein-Protein Interactions 1.0 null High grade glioma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.586 BBLN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.85485 ZBTB7A ENCODE Transcription Factor Targets 1.0 null Rectum adenocarcinoma_READ_TCGA-G5-6572-01A-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC7346528__F1 PFOCR Pathway Figure Associations 2024 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A700-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null stellate reticulum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.688 H3K4me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null synostosis of joints HPO Gene-Disease Associations 1.0 null H3K4me3_CD3 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BAMBI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64099 SCL-21571218-MEGAKARYOCYTES-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null JHOM2B CCLE Cell Line Gene Expression Profiles -1.0 -1.48771 GTEX-R55D-0126-SM-48FEL GTEx Tissue Sample Gene Expression Profiles 1.0 1.43223 NANOG-21062744-HESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Perturb_9517_Mut_Sall4_ERP111723 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.93992 Differentiated thyroid gland carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.467 Gli2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.1693 PMC11933697-41467_2025_58216_MOESM8_ESM.xlsx-SD6_ATF3_EV_NS1-SYMBOL_ATF3 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-PX3G-2426-SM-48TZZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.19976 Wing TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.166 ovarian neoplasm HPO Gene-Disease Associations 1.0 null GTEX-WFG8-1926-SM-4LVM1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.57831 HUP-T4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.20582 SNU520 CCLE Cell Line Gene Mutation Profiles 1.0 null eGFP-JUNB_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perineurium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.56 outer CP in ventromedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.40518 Adrenocortical carcinoma_ACC_TCGA-OR-A5LD-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AP3D1 Pathway Commons Protein-Protein Interactions 1.0 null TCF4-22108803-LS180-HUMAN ChEA Transcription Factor Targets 2022 1.0 null hippocampus (hippocampal formation)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.03325 pharynx TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.072596 NLRX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.04034 GTEX-V1D1-0006-SM-3NMCE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.850417 vertebral segmentation defect HPO Gene-Disease Associations 1.0 null endocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.532274 Ovarian Fibromata DisGeNET Gene-Disease Associations 1.0 null NANOG ChEA Transcription Factor Targets 1.0 null OVCA 420 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01878 KYSE-270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05664 frameshift GeneRIF Biological Term Annotations 1.0 null Childhood medulloblastoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.624 PMC9643473-Table1.xls-MAF_0_005-Gene_refGeneWithVer_MAF Rummagene Transcription Factor Associations 2026 1.0 null HNRNPH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39059 ZBTB7A_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE206870,GSE206872_0_v_2_ascl1_mouse RummaGEO Gene Perturbation Signatures -1.0 null TP53-22127205-IMR90-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null abnormality of cardiac morphology HPO Gene-Disease Associations 1.0 null abnormal hematopoiesis MPO Gene-Phenotype Associations 1.0 null BRD-K84090286 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.49115 VIIIA, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.982458 KRTAP13-4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.12478 CAL-72 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-PX3G-0006-SM-33HBQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03098 POLR2A_HGPS cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-UJMC-0008-SM-4IHKK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.2612 GTEX-OOBJ-0008-SM-3NB26 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.10124 HPS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.5957 dysostosis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.133282 DAP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49287 SLC52A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.15578 GTEX-OXRL-2126-SM-3NM98 GTEx Tissue Sample Gene Expression Profiles 1.0 0.962045 abnormal joint morphology HPO Gene-Disease Associations 1.0 null H3K4me3_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Neurobehavioral Manifestations CTD Gene-Disease Associations 1.0 1.22306 H3K4me3_WI38_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Physical disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.94 alopecia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.432646 GTEX-RNOR-2226-SM-2TF5O GTEx Tissue Sample Gene Expression Profiles 1.0 0.838049 GTEX-T6MN-0226-SM-32PMD GTEx Tissue Sample Gene Expression Profiles 1.0 0.972964 H2AFZ_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null autosomal dominant disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.888438 SIKE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.67664 laterodorsal subdivision of area 8 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.46892 cerebellar cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.26505 Syndactyly DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.333 CGAS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11575 GTEX-WEY5-0426-SM-3GIKT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.58688 Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3467-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PHYH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72682 H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HMY-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.2965 salivary gland HPA Tissue Gene Expression Profiles 1.0 2.24698 pachytene cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.920344 hippocampus (hippocampal formation)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.07708 POLR2A_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SW 1116 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.858562 RAD21_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTBP2 ENCODE Transcription Factor Targets 1.0 null Nkx3-1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.7431 cerebellum_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.03933 Activin AB complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.726 BRD-K13038935 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.86539 Neural tube defect DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.343 BRD-K84013239 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.09702 mimosine-6703 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.054305 H3K4me3_GM12864_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Carcinoma, Papillary DisGeNET Gene-Disease Associations 1.0 null LS1034 CCLE Cell Line Gene CNV Profiles -1.0 -1.37897 Sella Turcica, Bridged DisGeNET Gene-Disease Associations 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-V9-A7HT-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAZ_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC5730868__F1 PFOCR Pathway Figure Associations 2023 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81G-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null blood GTEx Tissue Gene Expression Profiles -1.0 -2.08344 BRD-K99074976 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.01902 GTEX-Q2AH-1526-SM-48TZG GTEx Tissue Sample Gene Expression Profiles 1.0 1.29629 FLI1-21571218-MEGAKARYOCYTES-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Prenatal Exposure Delayed Effects CTD Gene-Disease Associations 1.0 1.55476 MOLM6 CCLE Cell Line Gene Mutation Profiles 1.0 null BRD-K68300789 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 5.18988 abnormal bone marrow cell number MPO Gene-Phenotype Associations 1.0 null capan2 HPA Cell Line Gene Expression Profiles -1.0 -1.27651 EZH2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Mesenchyme TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.998 GSE154767_1_v_5_adam10_mouse RummaGEO Gene Perturbation Signatures -1.0 null Liver Neoplasms CTD Gene-Disease Associations 1.0 1.04352 TBL1XR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Synostosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.466 H3K27me3_H7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_bronchial epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-Q2AG-0626-SM-2S1PV GTEx Tissue Sample Gene Expression Profiles 1.0 1.14551 H3K4me3_Brain Germinal Matrix Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_4897_KD_U2AF1_SRP160510 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.02086 abnormality of calvarial morphology HPO Gene-Disease Associations 1.0 null inner SZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.8877 SNG-M COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-Q2AI-1226-SM-48U14 GTEx Tissue Sample Gene Expression Profiles 1.0 1.04076 H3K4me3_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null SJCRH30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.86537 BRD-K98833727 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.16462 H3K27me3_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null LOVO DepMap CRISPR Gene Dependency 1.0 2.35248 Hepatocellular carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.085 MYC-18358816-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null Mafb JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.8329 PMC6694122-41467_2019_11591_MOESM7_ESM.xlsx-f_CEBPA_DEGs-Gene_CEBPA Rummagene Transcription Factor Associations 2026 1.0 null H4K20me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K22949587 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.13461 posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.88862 HCC1171 CCLE Cell Line Gene Expression Profiles -1.0 -3.99888 abnormality of digit HPO Gene-Disease Associations 1.0 null GSE248045,GSE248046_0_v_1_runx1_mouse RummaGEO Gene Perturbation Signatures -1.0 null RCM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.937317 primary motor cortex (area M1, area 4)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.12069 posteroventral (inferior) parietal cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.41746 cerebellar cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.863947 Colonic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.424 GTEX-PWO3-1026-SM-2I5F2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.946625 protein binding GO Molecular Function Annotations 2015 1.0 null GTEX-Q2AG-0008-SM-48U2K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.36778 BRD-K10911459 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.36207 Lung non-small cell carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.319 ALS2CL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.50826 PRRC2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.1842 SNU-407 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-VUSH-0004-SM-3P61T GTEx Tissue Sample Gene Expression Profiles -1.0 -1.32344 XRCC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.74216 amygdaloid complex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.938728 decreased hematocrit MGI Mouse Phenotype Associations 2023 1.0 null Gastrointestinal Stromal Sarcoma DisGeNET Gene-Disease Associations 1.0 null regulation of biological process GO Biological Process Annotations 2015 1.0 null BRD-K40474424 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.64381 TBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.884 hamartomatous stomach polyps HPO Gene-Disease Associations 1.0 null Shox2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.9803 CHD7 ENCODE Transcription Factor Targets 1.0 null epidermal hyperplasia MPO Gene-Phenotype Associations 1.0 null posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.30448 KLF15_KO_GDS4780_509_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null mRNA_NIPBL_20720539 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Ubisch body COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.214 MAPK8IP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.36378 GTEX-QMR6-0008-SM-447AV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.854745 PMC7696523__F1 PFOCR Pathway Figure Associations 2024 1.0 null GSE153137,GSE153140_2_v_1_mettl5_mouse RummaGEO Gene Perturbation Signatures -1.0 null vertebrate muscular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053552 Perturb_15227_OE_Gai2_SRP059824 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 11.5307 Feather bud TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.508 abnormality of the oral cavity HPO Gene-Disease Associations 1.0 null GSE104508_0_v_1_dnmt3a_mouse RummaGEO Gene Perturbation Signatures 1.0 null COLO 678 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.072 H3K4me1_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null TE8 CCLE Cell Line Gene Expression Profiles -1.0 -2.18536 H3K4me3_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.19803 EPRS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40617 Pollen coat COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.615 Brain Lower Grade Glioma_LGG_TCGA-P5-A5F1-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-RWS6-0005-SM-2XCAN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04052 Multiple myeloma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.108 Palmar Pit DisGeNET Gene-Phenotype Associations 1.0 null ventral medial nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.93915 BRD-K66577743 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.70188 Growth Disorders CTD Gene-Disease Associations 1.0 1.09998 GSE179531_1_v_0_metformin_mouse RummaGEO Drug Perturbation Signatures 1.0 null OVMANA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.96045 SUM 149PT Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.13674 NOC3L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.01611 ventrolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.3091 H3K4me3_Neurosphere Cultured Cells Cortex Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null uterine endometrium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.65746 abnormality of the spinal cord HPO Gene-Disease Associations 1.0 null somite TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.726507 GSE111061_1_v_0_tofacitinib_human RummaGEO Drug Perturbation Signatures -1.0 null dorsolateral prefrontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.87215 leiomyosarcoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.165435 H3K4me3_fibroblast of foreskin _hg19_2 ENCODE Histone Modification Site Profiles 1.0 null SNU-175 COSMIC Cell Line Gene Mutation Profiles 1.0 null CCDC186 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.6349 ovarian fibroma HPO Gene-Disease Associations 1.0 null H3K4me3_mammary epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null gametocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.205634 BRD-K90475322 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.44193 PMC6761967__F5 PFOCR Pathway Figure Associations 2024 1.0 null KMS-28PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.8816 Brain Lower Grade Glioma_LGG_TCGA-WH-A86K-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null floor plate TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.276846 abnormal phagocyte morphology MPO Gene-Phenotype Associations 1.0 null H3K4me3_CD8 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null AE-39-DG66_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.247203 Calvarium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.897 Outer dental epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.488 H3K4me3_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K94018786 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05256 CAL51 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.59515 GSE122067_2_v_1_mtch2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Uterine disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.249 H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K62800316 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.3624 eye and adnexa disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.046541 superficial layers of caudal presubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.03603 TT2609-C02 COSMIC Cell Line Gene Mutation Profiles 1.0 null solasodine-4305 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null H3K4me3_CD14-positive monocyte_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null PUS7L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.67933 TRAK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.13194 IGR39 CCLE Cell Line Gene Mutation Profiles 1.0 null GTEX-S7SF-0001-SM-3K2BE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.43248 GTEX-XYKS-0002-SM-4BRWN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16524 mesoderm TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.06735 primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.10331 INA6 DepMap CRISPR Gene Dependency 1.0 2.58264 GTEX-WYJK-0526-SM-3NM8Z GTEx Tissue Sample Gene Expression Profiles 1.0 1.09203 Perturb_9390_KO_Arid1a_SRP299730 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.78554 abnormality of the forehead HPO Gene-Disease Associations 1.0 null PMC3348545-NIHMS263168-supplement-3.pdf-41-ZNF691_ZNF691 Rummagene Transcription Factor Associations 2026 1.0 null STOML2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.67499 OLIG2-26023283-AINV15-MOUSE ChEA Transcription Factor Targets 2022 1.0 null PMC9643473-Table1.xls-MAF_0_005-Gene_refGenecanonical_MAF Rummagene Transcription Factor Associations 2026 1.0 null Ovarian clear cell carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.017 abnormality of the hand HPO Gene-Disease Associations 1.0 null Hair disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.763 PLIN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.22603 MDA-MB-175-VII Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.98151 Melanophore TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.801 Gill filament TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.56 TMEM151A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.06445 hsa-miR-3121-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 ZNF384 ENCODE Transcription Factor Targets 1.0 null small intestine HPA Tissue Protein Expression Profiles 1.0 0.96344 TBX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.9375 DCLRE1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.81882 MFE-319 COSMIC Cell Line Gene Mutation Profiles 1.0 null abnormality of forebrain morphology HPO Gene-Disease Associations 1.0 null SP in perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.865481 Perturb_7435_OE_HNRNPA1_SRP077661 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.58017 GTEX-WH7G-0005-SM-3NMBX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.38248 SOX2-21211035-LN229-HUMAN ChEA Transcription Factor Targets 2022 1.0 null outer plexiform zone in extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.99231 NCI-H2081 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.934329 Cataract DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.072 whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.02381 IX, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.75919 BRD-K31584969 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.1989 H3K4me3_Pancreatic Islets Roadmap Epigenomics Histone Modification Site Profiles 1.0 null inner CP in dorsomedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.17101 TNRC6A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31053 intrinsic component of membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.107461 MED13L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31786 TUBB Pathway Commons Protein-Protein Interactions 1.0 null PXDNL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.00861 abnormality of the gastrointestinal tract HPO Gene-Disease Associations 1.0 null POLR2AphosphoS5_Panc1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null aplasia/hypoplasia of the distal phalanges of the hand HPO Gene-Disease Associations 1.0 null VACTERL association DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.09 GTEX-OHPL-0326-SM-33HC8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.916835 PMC5730868__F1 PFOCR Pathway Figure Associations 2024 1.0 null GTEX-WFON-2026-SM-4LVMW GTEx Tissue Sample Gene Expression Profiles 1.0 1.49173 Perturb_17042_KO_Phf6_SRP153916 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 12.5971 Meningioma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.576 PDE5A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.07916 ChIP_POU5F1_18358816 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null TAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39191 GSE242199_9_v_11_ntrk2_human RummaGEO Gene Perturbation Signatures -1.0 null WDFY2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11923 H3K4me1_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Mandibular nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.721 NALM6 CCLE Cell Line Gene Mutation Profiles 1.0 null hippocampus (hippocampal formation)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.49158 COL5A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.70726 RANBP9 Pathway Commons Protein-Protein Interactions 1.0 null ITFG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.13258 H3K27me3_cardiac mesoderm_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RTLS-0326-SM-2TF6A GTEx Tissue Sample Gene Expression Profiles 1.0 0.966818 Alveolar bone TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.563 ARL10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.75759 PMC6200785__F8 PFOCR Pathway Figure Associations 2023 1.0 null PMC5831777__F3 PFOCR Pathway Figure Associations 2024 1.0 null Congenital Coloboma Of Iris DisGeNET Gene-Disease Associations 1.0 null EOMES JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.1532 NCIH1876 CCLE Cell Line Gene CNV Profiles 1.0 1.55775 SNU-398 COSMIC Cell Line Gene Mutation Profiles 1.0 null reticulotegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.981683 heart BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.842468 Ciliary tip COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.568 Salivary_Gland-acinar cell of salivary gland Tabula Sapiens Gene-Cell Associations 1.0 16.2402 GSE169571_5_v_4_dexamethasone_mouse RummaGEO Drug Perturbation Signatures -1.0 null AZIN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.06709 TEAD4_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KMS-12-BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.72349 H3K4me3_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K62236460 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00935 GTEX-WFG8-0626-SM-3GILJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.60215 BRD-K99446825 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.30847 primary auditory cortex (core)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.2159 FAF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27296 IZ in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.34852 EP300_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Tail bud TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.187 POLR2A_small intestine_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Hematopoietic system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.544 GTEX-UPJH-0126-SM-4IHLL GTEx Tissue Sample Gene Expression Profiles 1.0 1.48857 vesicle LOCATE Curated Protein Localization Annotations 1.0 null parabigeminal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.911863 placenta HPA Tissue Gene Expression Profiles -1.0 -1.59169 abnormal blood cell morphology/development MPO Gene-Phenotype Associations 1.0 null G130 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.832389 blood vessel TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053451 H3K27ac_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-XPVG-2226-SM-4B65U GTEx Tissue Sample Gene Expression Profiles 1.0 1.48651 GTEX-N7MS-0326-SM-4E3K2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.911325 hippocampus HPA Tissue Protein Expression Profiles -1.0 -0.897918 AE-18-ZM98_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.215959 stomach_3b HPA Tissue Sample Gene Expression Profiles -1.0 -1.03665 BRD-K00663064 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.72557 cell property TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.162999 Lens disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.07 IV Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.89328 GTEX-WZTO-3026-SM-3NMA2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.06373 Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20R-11A-11R-A16R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Retinal cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.118 NCBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.51384 GTEX-XMK1-2426-SM-4B66I GTEx Tissue Sample Gene Expression Profiles 1.0 1.91198 MERO48A DepMap CRISPR Gene Dependency 1.0 3.83089 H3K27ac_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Sarcoma_SARC_TCGA-DX-AB2J-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null germ cell cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.933727 H3K4me3_foreskin fibroblast_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null MAX_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null congenital GeneRIF Biological Term Annotations 1.0 null RAD21_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH2887 DepMap CRISPR Gene Dependency 1.0 2.54045 Uterine Cervical Neoplasms CTD Gene-Disease Associations 1.0 1.166 H3K4me3_Adult Liver Roadmap Epigenomics Histone Modification Site Profiles 1.0 null retina TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.367876 PMC3737722__F7 PFOCR Pathway Figure Associations 2024 1.0 null MYH9 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_endothelial cell of umbilical vein_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null increased granulocyte number MPO Gene-Phenotype Associations 1.0 null H3K4me1_G1E-ER4_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-O5YT-0326-SM-32PKA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.28659 gonadal neoplasm GWASdb SNP-Phenotype Associations 1.0 0.33716 TDRKH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22077 TMEM184C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.93919 regulation of smoothened signaling pathway GO Biological Process Annotations 2023 1.0 null PMC10975450__F2 PFOCR Pathway Figure Associations 2024 1.0 null GTEX-XMK1-0008-SM-4GICF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.857088 u138mg HPA Cell Line Gene Expression Profiles -1.0 -1.9716 oligodendroglioma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.261599 DGKZ Pathway Commons Protein-Protein Interactions 1.0 null Enamel knot TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.591 primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.6992 peripheral nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.225647 GTEX-XBED-0526-SM-47JY3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.988671 GTEX-U8T8-1126-SM-4DXUE GTEx Tissue Sample Gene Expression Profiles 1.0 1.14768 H3K9ac_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null abnormality of the ovary HPO Gene-Disease Associations 1.0 null Ectexine COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.784 eGFP-JUND_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Common cardinal vein TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.533 PL45 CCLE Cell Line Gene CNV Profiles -1.0 -1.50117 bone disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.077896 leukemia cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.065424 RCC4 CCLE Cell Line Gene CNV Profiles 1.0 1.90598 16397233-Table2 GeneSigDB Published Gene Signatures 1.0 null BRD-K56776985 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.36214 Stellate reticulum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.293 KM12 COSMIC Cell Line Gene Mutation Profiles 1.0 null PAX5_GM12892_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SJSA-1 GDSC Cell Line Gene Expression Profiles 1.0 1.45687 GTEX-T5JC-0001-SM-3NMAK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14506 RPS7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99226 GSE165939_2_v_1_poldip2_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_WERI-Rb-1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null medial geniculate complex, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.42384 uterine benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.295492 soft tissue HPA Tissue Protein Expression Profiles -1.0 -1.18918 hydrocephalus HPO Gene-Disease Associations 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5081-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null abnormality of globe location HPO Gene-Disease Associations 1.0 null organelle LOCATE Predicted Protein Localization Annotations 1.0 null Congenital Kyphoscoliosis DisGeNET Gene-Disease Associations 1.0 null VIIB, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.955569 GTEX-T6MN-2026-SM-4DM7L GTEx Tissue Sample Gene Expression Profiles 1.0 1.35655 NB1 COSMIC Cell Line Gene Mutation Profiles 1.0 null no abnormal phenotype detected MGI Mouse Phenotype Associations 2023 1.0 null GSE162892_3_v_0_isox_human RummaGEO Drug Perturbation Signatures 1.0 null pulmonary valve stenosis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.508041 EP300_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE248045,GSE248046_6_v_1_runx1_mouse RummaGEO Gene Perturbation Signatures -1.0 null bladder cancer GAD Gene-Disease Associations 1.0 null GTEX-WWYW-0005-SM-3NB3K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.31074 MOLT-13 COSMIC Cell Line Gene Mutation Profiles 1.0 null SARS-CoV MA15_Day7-PFU-10^3_None_GSE33266 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.00622 GTEX-WVLH-0006-SM-3MJF7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.27985 abnormality of the shoulder HPO Gene-Disease Associations 1.0 null GTEX-UPJH-0001-SM-3NMDE GTEx Tissue Sample Gene Expression Profiles -1.0 -2.32264 SOX2-18692474-MEFS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Male reproductive organ cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.484 H3K4me1_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.765943 JUND_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RPP38 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47311 H3K4me3_BJ_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null blood TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.057326 BRD-K88658905 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.23827 PMC11533552-mmc1.docx-1-AR_AR Rummagene Transcription Factor Associations 2026 1.0 null BRD-K06398048 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.1285 RBBP5 ENCODE Transcription Factor Targets 1.0 null SNU-719 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.92419 Kidney disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.408 Thoracic cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.688 SMAD4-21799915-A2780-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Hindgut TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.177 H3K4me3_cardiac mesoderm_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-PWCY-1326-SM-48TCU GTEx Tissue Sample Gene Expression Profiles 1.0 1.75112 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FV-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null abnormality of the abdominal organs HPO Gene-Disease Associations 1.0 null T-47D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.24636 Carney complex DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.315 PEX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.29932 PMC4965740__F9 PFOCR Pathway Figure Associations 2024 1.0 null MFE-280 COSMIC Cell Line Gene Mutation Profiles 1.0 null short 4th metacarpal HPO Gene-Disease Associations 1.0 null Central nervous system benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.003 hedgehog receptor activity GO Molecular Function Annotations 2025 1.0 null receptor activity GO Molecular Function Annotations 2015 1.0 null FLI1-21571218-MEGAKARYOCYTES-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null H3K4me3_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Dental Caries DisGeNET Gene-Disease Associations 1.0 null GSE182680,GSE182683_5_v_6_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null Retinal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.154 H3K4me3_WI38_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null neuroblastoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.069147 NALM-6 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.904941 Perturb_1419_OE_Irf7_SRP324838 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 amygdaloid complex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.76954 KLF5 JASPAR Predicted Transcription Factor Targets 1.0 null Crus II, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.30082 LU-139 GDSC Cell Line Gene Expression Profiles -1.0 -1.58879 captopril_mus musculus_gpl1261_gds3683 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null abdomen TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.070946 JEKO1 CCLE Cell Line Gene CNV Profiles -1.0 -1.42116 H2AFZ_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K34797601 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.20439 BRD-K34980742 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.19277 Hydrocephalus DisGeNET Gene-Disease Associations 1.0 null GRHPR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.86307 Cerebral falx meningioma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.071 decreased lymphocyte cell number MGI Mouse Phenotype Associations 2023 1.0 null NOL11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 5.9248 GPCR ligand binding Reactome Pathways 2014 1.0 null inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.05959 BRD-K86923998 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.12528 ES5 COSMIC Cell Line Gene Mutation Profiles 1.0 null u937 HPA Cell Line Gene Expression Profiles 1.0 1.42154 VMRC-LCD Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.92419 SRRT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12779 PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context3-Nearest_Ensembl_ATF3 Rummagene Transcription Factor Associations 2026 1.0 null plasma membrane part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.043296 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HOXC6_HOXC6 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_bronchial epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HNF4A JASPAR Predicted Transcription Factor Targets 1.0 null CREB1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null THP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.2525 H3K9ac_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null T-cell acute lymphoblastic leukemia cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.088 NCI-H1437 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07599 epithelium development GO Biological Process Annotations 2015 1.0 null abnormal hematopoietic cell number MPO Gene-Phenotype Associations 1.0 null Stomach TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 intracellular membrane-bounded organelle LOCATE Curated Protein Localization Annotations 1.0 null muscle cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.279011 ZNF143_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HDAC2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null VZ in subcallosal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.32601 GLI proteins bind promoters of Hh responsive genes to promote transcription Reactome Pathways 2024 1.0 null GSE157296,GSE157298_4_v_3_kbtbd4_human RummaGEO Gene Perturbation Signatures 1.0 null sarcoma HPO Gene-Disease Associations 1.0 null EP300 ENCODE Transcription Factor Targets 1.0 null dorsolateral prefrontal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.938728 A375 GDSC Cell Line Gene Expression Profiles 1.0 1.48241 abnormality of skull size HPO Gene-Disease Associations 1.0 null H3K27me3_bronchial epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null heart muscle HPA Tissue Protein Expression Profiles 1.0 0.96344 GTEX-TMZS-0001-SM-3P61Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.25044 Neoplasms CTD Gene-Disease Associations 1.0 1.30269 NCI-H2126 COSMIC Cell Line Gene Mutation Profiles 1.0 null an3ca HPA Cell Line Gene Expression Profiles 1.0 1.24645 SW48 CCLE Cell Line Gene Mutation Profiles 1.0 null leiomyoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.161331 ChIP_RCOR3_21632747 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null ATP5PF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46193 salivarygland_6c HPA Tissue Sample Gene Expression Profiles 1.0 3.47528 H3K4me3_fibroblast of mammary gland_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null locus GeneRIF Biological Term Annotations 1.0 null GSE190534,GSE190536_0_v_1_cyclophosphamide_mouse RummaGEO Drug Perturbation Signatures -1.0 null SNU1040 CCLE Cell Line Gene Mutation Profiles 1.0 null NCIH209 CCLE Cell Line Gene CNV Profiles -1.0 -2.23467 GSE242199_6_v_11_ntrk2_human RummaGEO Gene Perturbation Signatures -1.0 null ZNF135 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 63.4367 NAT14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.14454 smoothened binding GO Molecular Function Annotations 2023 1.0 null morphological abnormality of the gastrointestinal tract HPO Gene-Disease Associations 1.0 null Ribonuclease MRP complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.285 Intracranial meningioma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.074 Liver Diseases CTD Gene-Disease Associations 1.0 1.50776 Thyroid gland disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.783 HDLM-2 GDSC Cell Line Gene Expression Profiles -1.0 -1.78183 hsa-miR-1915 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 Parietal Bossing DisGeNET Gene-Phenotype Associations 1.0 null BRD-K91239327 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.27621 Sterol-sensing domain InterPro Predicted Protein Domain Annotations 1.0 null MOLT-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-U3ZG-0006-SM-47JWX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.62596 uterus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.529508 CP67-MEL COSMIC Cell Line Gene Mutation Profiles 1.0 null spina bifida HPO Gene-Disease Associations 1.0 null T-98 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.938 GTEX-P4PP-1726-SM-2S1NS GTEx Tissue Sample Gene Expression Profiles 1.0 0.964552 LRP1B Pathway Commons Protein-Protein Interactions 1.0 null H3K27me3_cardiac mesoderm_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PHF8-20622853-HELA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Inner dental epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.772 ventrolateral prefrontal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.23002 MiaPaCa-2 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.969 XRN2-22483619-HELA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null BRD-K09863466 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.42671 hsa-miR-767-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 ets_00000000_2008_ovarian_cancer_cells_gof_human_gpl6244_gse21129 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.25295 BRD-K98271666 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.35136 POLR2A_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QVJO-1325-SM-2S1QX GTEx Tissue Sample Gene Expression Profiles 1.0 0.972781 H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ChIP_CTCF_18555785 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null ozagrel-5983 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null H3K4me3_keratinocyte_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null DNA polymerase III, clamp loader complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.775 abnormality of the anterior segment of the eye HPO Gene-Disease Associations 1.0 null GSE169356_2_v_5_ivermectin_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-UTHO-0011-R11A-SM-3GIJE GTEx Tissue Sample Gene Expression Profiles 1.0 0.846346 H3K4me3_astrocyte of the cerebellum_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null prostate HPA Tissue Protein Expression Profiles 1.0 0.96344 PCDHB6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05959 RB1_KD_GSE50532_660_human_OSTEOBLASTS GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null BRD-K07557785 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.16224 SK-N-LO cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.915 PMC7720970__F1 PFOCR Pathway Figure Associations 2024 1.0 null cerebellar cortex_35 pcw_F_12295 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.79501 GSE65617_5_v_1_aire_mouse RummaGEO Gene Perturbation Signatures -1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-UZ-A9PN-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WY7C-0006-SM-3NB3L GTEx Tissue Sample Gene Expression Profiles -1.0 -1.10782 GSE162892_4_v_2_isox_human RummaGEO Drug Perturbation Signatures 1.0 null chinese GeneRIF Biological Term Annotations 1.0 null mature ovarian follicle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.123879 IGROV-1 GDSC Cell Line Gene Expression Profiles 1.0 1.5778 GTEX-WFJO-0005-SM-3GIKY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11305 HIST1H2BO Pathway Commons Protein-Protein Interactions 1.0 null U-2 OS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.988795 KLF4-18358816-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE211215_1_v_0_pemetrexed_human RummaGEO Drug Perturbation Signatures 1.0 null integument TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.872749 Medullomyoblastoma DisGeNET Gene-Disease Associations 1.0 null Peritubular contractile cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.024 LHX9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.0348 APLP1 Pathway Commons Protein-Protein Interactions 1.0 null Myeloid leukemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.405 PWR-1E COSMIC Cell Line Gene Mutation Profiles 1.0 null skin tags HPO Gene-Disease Associations 1.0 null disease of cellular proliferation GWASdb SNP-Disease Associations 1.0 0.113278 BRD-K42455540 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00127 GSE199255,GSE199356_0_v_1_pds5a_mouse RummaGEO Gene Perturbation Signatures -1.0 null Floor plate TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.92 Neural plate TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.42 Central Neuroblastoma DisGeNET Gene-Disease Associations 1.0 null QTRT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.13236 BRD-K87159315 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.12911 KARPAS299 CCLE Cell Line Gene Mutation Profiles 1.0 null ATF6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.1999 PMC6887651-Table_1.xlsx-Sheet1-SRY_SRY Rummagene Transcription Factor Associations 2026 1.0 null GSE247764_3_v_2_nell2_mouse RummaGEO Gene Perturbation Signatures 1.0 null testicular cancer GWASdb SNP-Disease Associations 1.0 0.739121 ameloblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.552093 pedunculo(pontine) tegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.07526 H3K4me3_choroid plexus epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null artery TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056465 PMC3720582__F1 PFOCR Pathway Figure Associations 2023 1.0 null GTEX-QDT8-0326-SM-32PL1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.03957 BRD-K51600962 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07099 MAP3K14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.18968 telmisartan_rattus norvegicus_gpl4135_gse29445 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Gorlin syndrome ClinVar Gene-Phenotype Associations 2025 1.0 null H3K4me3_erythroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null distinct GeneRIF Biological Term Annotations 1.0 null abnormal ossification of hand bones HPO Gene-Disease Associations 1.0 null gonad TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.588031 PMC3889689-elife01439s001.xls-RFX2_rnaseq_chip_DirectDE_final-GeneName_RFX2 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-TML8-0001-SM-3NMAF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04535 H3K4me3_epithelial cell of proximal tubule_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE48812_3_v_6_sulforaphane_human RummaGEO Drug Perturbation Signatures 1.0 null SA1-27219007-CHIP-SEQ-BCELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-TKQ1-0926-SM-4DXU2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.23411 Integumentary system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.559 H2595 COSMIC Cell Line Gene Mutation Profiles 1.0 null signalling GeneRIF Biological Term Annotations 1.0 null H3K27me3_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hamartomatous polyps HPO Gene-Disease Associations 1.0 null BRD-K59120074 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.02488 L363 CCLE Cell Line Gene Expression Profiles 1.0 1.47629 GSE174406_2_v_1_lin28b_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-XOT4-0226-SM-4B66Z GTEx Tissue Sample Gene Expression Profiles 1.0 0.854641 ZR7530 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.03705 GTEX-XBEW-0008-SM-4AT3Y GTEx Tissue Sample Gene Expression Profiles -1.0 -0.971359 qt35 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.319 POU5F1-18700969-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Crus II, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.55754 GSE81193_3_v_5_irf3_mouse RummaGEO Gene Perturbation Signatures -1.0 null BRD-A02501536 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.18603 CL34 CCLE Cell Line Gene Mutation Profiles 1.0 null SNU-484 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.63784 BRD-A54347351 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.75318 BRD-K02395808 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.01039 Acute Myeloid Leukemia_LAML_TCGA-AB-3011-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null postcentral gyrus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.222224 GSE104508_2_v_1_dnmt3a_mouse RummaGEO Gene Perturbation Signatures 1.0 null A172 BioGPS Cell Line Gene Expression Profiles -1.0 -1.05998 GTEX-P4PQ-0326-SM-2HMJ8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.19362 BRD-K98805845 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.02533 vertebral wedging HPO Gene-Disease Associations 1.0 null GSE229978_4_v_7_morphine_mouse RummaGEO Drug Perturbation Signatures -1.0 null Syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.34 FLI1-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null H2AFZ_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null IRE1-RACK1-PP2A complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.101 Dorsal endoderm TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.744 Ventral pallidus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.890316 medial subdivision of central nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.26359 abnormal neutrophil cell number MPO Gene-Phenotype Associations 1.0 null H3K4me3_lung_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NALM-6 COSMIC Cell Line Gene Mutation Profiles 1.0 null motor delay HPO Gene-Disease Associations 1.0 null hsa-miR-3649 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 CHP-212 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.24295 H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null TBX2-33478486-IMR90-HUMAN-LUNG ChEA Transcription Factor Targets 2022 1.0 null phenotypic abnormality HPO Gene-Disease Associations 1.0 null SU-DHL-10 COSMIC Cell Line Gene Mutation Profiles 1.0 null SNU738 CCLE Cell Line Gene CNV Profiles 1.0 1.65488 BRD-K79438478 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.33578 GSE242199_6_v_3_ntrk2_human RummaGEO Gene Perturbation Signatures -1.0 null primary motor-sensory cortex (samples)_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.0092 KARPAS-299 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-OHPK-0006-SM-2HMKH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.15382 GTEX-XBEC-0006-SM-4AT5T GTEx Tissue Sample Gene Expression Profiles -1.0 -1.61456 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4822-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Urogenital Abnormalities CTD Gene-Disease Associations 1.0 1.40457 KYSE-70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.51685 NCI-H841 COSMIC Cell Line Gene Mutation Profiles 1.0 null FADU Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05745 Perturb_5172_KO|KD_Sirt1|Otx2_SRP075247 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 Germ layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.198 GSE188458_2_v_1_hydrogen peroxide_human RummaGEO Drug Perturbation Signatures 1.0 null Uterine endometrium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.787 LRRC57 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.73521 mammalian phenotype MPO Gene-Phenotype Associations 1.0 null HA1E DepMap CRISPR Gene Dependency 1.0 2.47739 stomach HPA Tissue Protein Expression Profiles 1.0 0.96344 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JB-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DB-A4X9-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null APCDD1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.20745 HEC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null HSPA5 Pathway Commons Protein-Protein Interactions 1.0 null dorsolateral prefrontal cortex_8 yrs_M_12981 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.35632 abnormality of the integument HPO Gene-Disease Associations 1.0 null kyphosis HPO Gene-Disease Associations 1.0 null RUNX3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null IST-SL1 GDSC Cell Line Gene Expression Profiles 1.0 1.56735 PMC3715061__F1 PFOCR Pathway Figure Associations 2024 1.0 null endoderm TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.34334 GSE94849_1_v_2_pinometostat_human RummaGEO Drug Perturbation Signatures -1.0 null Brain Lower Grade Glioma_LGG_TCGA-QH-A6CV-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null aplasia/hypoplasia of the 4th metacarpal HPO Gene-Disease Associations 1.0 null genital neoplasm GWASdb SNP-Phenotype Associations 1.0 0.265254 Ovarian cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.488 griseofulvin-3664 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K28563387 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.025 primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.66118 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4811-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE242199_9_v_0_ntrk2_human RummaGEO Gene Perturbation Signatures -1.0 null Tail fin TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.084 HCC1195 CCLE Cell Line Gene CNV Profiles 1.0 1.96275 KDM5B_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Endocrine gland cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.984 posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.13696 H3K4me3_GM12878_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null granule cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.222224 BRD-K39087188 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.73336 H3K4me3_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K06842972 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.71888 SG in rostral perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.33431 Hematologic cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.654 primary auditory cortex (core)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.908924 morphological abnormality of the central nervous system HPO Gene-Disease Associations 1.0 null superior olivary complex, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.891647 medulloblastoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.31537 Craniofacial region TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.956 H3K4me3_fibroblast of villous mesenchyme_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null abnormality of the teeth HPO Gene-Disease Associations 1.0 null Skin Neoplasms HuGE Navigator Gene-Phenotype Associations 1.0 null POLR2AphosphoS5_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null membrane-bounded vesicle LOCATE Curated Protein Localization Annotations 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3308-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Gas bladder TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.386 HELA COSMIC Cell Line Gene Mutation Profiles 1.0 null abnormal conjugate eye movement HPO Gene-Disease Associations 1.0 null somatosensory cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.230382 neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.062661 Mre11 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.267 H3K4me1_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Macrocephaly DisGeNET Gene-Disease Associations 1.0 null Accessory Rib DisGeNET Gene-Disease Associations 1.0 null ChIP_POU5F1_18700969 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Sarcoma_SARC_TCGA-DX-AB2T-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null U937 DepMap CRISPR Gene Dependency 1.0 2.42185 GTEx Heart 20-29 vs 30-39 GTEx Tissue-Specific Aging Signatures 1.0 3.06729 TMEM35A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31123 GTEX-SNOS-0003-SM-3NMAO GTEx Tissue Sample Gene Expression Profiles -1.0 -2.01693 Tailbud stage TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.038 developmental process GO Biological Process Annotations 2015 1.0 null Blastema TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.838 Ovary Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 1.59711 Short Ribs DisGeNET Gene-Phenotype Associations 1.0 null H1_BMP4_Derived_Trophoblast_Cultured_Cells Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -0.911558 LTBR_INHIBITION - 1 Day_GDS2005_728_mouse_Lymph nodes (MG-430B) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null HCC515 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.17396 H3K4me3_B cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null IGR37 CCLE Cell Line Gene Mutation Profiles 1.0 null Venous endothelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.698 dexamethasone_homo sapiens_gpl4133_gse42619 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-N7MS-0126-SM-3TW8O GTEx Tissue Sample Gene Expression Profiles 1.0 1.40478 hairy cell leukemia cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.517678 PMC6279925__F4 PFOCR Pathway Figure Associations 2023 1.0 null EWSR1_KD_GDS4962_468_human_Ewing sarcoma and prostate cancer GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GSE189683_1_v_2_rif1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Retinoblastoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.056 MAVS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.61459 H3K4me3_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_CD34 Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE248883_0_v_1_shmt2_mouse RummaGEO Gene Perturbation Signatures 1.0 null CRCGN009_HEPG2_24H:H15 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.3471 EGR1 ChEA Transcription Factor Targets 1.0 null abnormal external genitalia GWASdb SNP-Phenotype Associations 1.0 0.238005 Epiphyseal growth plate TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.024 BRD-K15694916 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.46157 neoplasm of the lung GWASdb SNP-Phenotype Associations 1.0 0.638004 MSANTD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.48037 Mouth disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.419 GTEX-QEG5-0006-SM-2I5FZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02754 Thyroid Neoplasm DisGeNET Gene-Disease Associations 1.0 null H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NCI-H520 COSMIC Cell Line Gene Mutation Profiles 1.0 null EFM19 DepMap CRISPR Gene Dependency 1.0 3.52432 GTEX-XBED-0003-SM-47JWP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.25338 Cancer pathways WikiPathways Pathways 2024 1.0 null abnormality of the iris HPO Gene-Disease Associations 1.0 null PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_downregulated_genes-Unnamed_7_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null CTCF_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null EGR1 ENCODE Transcription Factor Targets 1.0 null GTEX-OOBK-0008-SM-3NB27 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.960175 GTEX-W5WG-0002-SM-3NMDN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13069 Brain Lower Grade Glioma_LGG_TCGA-DU-5847-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsolateral prefrontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.950791 ZNF384_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K40612106 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.52082 Glioblastoma classical subtype DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.309 KDM4A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XMK1-0001-SM-4B64F GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02471 GSE112860_3_v_4_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE133070_2_v_4_prss1_mouse RummaGEO Gene Perturbation Signatures 1.0 null BRD-K08527280 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.35934 carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.053885 TTF2-22483619-HELA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null SRY CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.08382 Endoderm TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.497 POLR2A_H54_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-A98099470 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.32975 Aa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.532 POLR1A Pathway Commons Protein-Protein Interactions 1.0 null Perturb_9500_KI_Trp53_SRP201382 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.90571 UM-UC-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null hsa-miR-761 TargetScan Predicted Conserved microRNA Targets 1.0 0.123298 IFITM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.50578 GTEX-WH7G-2626-SM-3NMBE GTEx Tissue Sample Gene Expression Profiles 1.0 0.855974 BRD-K96057608 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.59576 BRD-K29756429 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.3741 PMC4782046-supp_30.5.508_TableS2.xlsx-TAL1_UTX-co-bound_genes-Table_S2_List_of_TAL1_UTX_co-bound_genes_in_Jurkat_cells_TAL1 Rummagene Transcription Factor Associations 2026 1.0 null CRCGN010_HEPG2_24H:H22 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.09885 abnormality of neural tube closure HPO Gene-Disease Associations 1.0 null abnormal heart left ventricle morphology IMPC Knockout Mouse Phenotypes 1.0 null colonrectum_d HPA Tissue Sample Gene Expression Profiles -1.0 -0.956633 H3K4me3_Brain Anterior Caudate Roadmap Epigenomics Histone Modification Site Profiles 1.0 null gonadal neoplasm HPO Gene-Disease Associations 1.0 null GSE237040_4_v_3_notch3_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC5288170__F1 PFOCR Pathway Figure Associations 2024 1.0 null GTEX-X3Y1-2426-SM-3P5Z7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.863799 phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.032895 Thymus BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.67879 abnormal hand bone ossification HPO Gene-Disease Associations 1.0 null H3K4me1_erythroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K46924722 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.32286 ISLR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.78275 BRD-K46897949 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.58123 DNPH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.7705 SMAD4 ChEA Transcription Factor Targets 1.0 null H3K4me3_WI38_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null GSE139966_4_v_3_figla_mouse RummaGEO Gene Perturbation Signatures -1.0 null pancreas BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.0737 Rhabdomyosarcoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.993 GTEX-P4PQ-0005-SM-2HMKJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.9268 Central element COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.557 GTEX-NL3H-0008-SM-4E3HU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.10298 PTF1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55654 GTEX-XLM4-2926-SM-4AT59 GTEx Tissue Sample Gene Expression Profiles 1.0 0.912307 X-linked dominant disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.801 GTEX-XPT6-1626-SM-4B655 GTEx Tissue Sample Gene Expression Profiles 1.0 1.32711 H3K27me3_Breast vHMEC Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SCYL2 Pathway Commons Protein-Protein Interactions 1.0 null Disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.415 GTEX-XXEK-0004-SM-4BRWO GTEx Tissue Sample Gene Expression Profiles -1.0 -2.34563 BRD-K18101782 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.59818 RIC8A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35028 GTEX-X4EO-0126-SM-3P5YN GTEx Tissue Sample Gene Expression Profiles 1.0 1.68175 triangular shaped phalanges of the hand HPO Gene-Disease Associations 1.0 null Incisor TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.368 abnormality of the cerebral ventricles HPO Gene-Disease Associations 1.0 null RCOR3-21632747-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GSE182680,GSE182683_0_v_13_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null HS852T CCLE Cell Line Gene Expression Profiles -1.0 -1.74519 Melanotic Medulloblastoma DisGeNET Gene-Disease Associations 1.0 null H3K4me3_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null A2780 COSMIC Cell Line Gene Mutation Profiles 1.0 null abnormality of the genitourinary system HPO Gene-Disease Associations 1.0 null Bud TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.95 Pancreas disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.804 H3K4me3_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null abnormality of limb bone morphology HPO Gene-Disease Associations 1.0 null Keratocystic Odontogenic Tumor DisGeNET Gene-Disease Associations 1.0 null Schistosomiasis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.042 CBX3 ENCODE Transcription Factor Targets 1.0 null NCI-H847 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.866776 neoplasm of the gastrointestinal tract HPO Gene-Disease Associations 1.0 null coarse facial features HPO Gene-Disease Associations 1.0 null TMPO Pathway Commons Protein-Protein Interactions 1.0 null BRD-K46792957 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.11745 16610948-Table3 GeneSigDB Published Gene Signatures 1.0 null hair disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.366671 H2AFZ_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-TMZS-0006-SM-3DB8G GTEx Tissue Sample Gene Expression Profiles -1.0 -1.10442 stratum intermedium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.31379 DNAJC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30553 Arachnodactyly DisGeNET Gene-Disease Associations 1.0 null gut TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.106699 leg muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.079983 ChIP_KLF4_18555785 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Pancreatic adenocarcinoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.179 H3K9ac_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null LXR-22292898-THP-1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null H3K4me2_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.412 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 enamel epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.12172 proxymetacaine-5433 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Perturb_6766_KD_PAF1_SRP103746 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.16379 SET-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.906199 NDUFS1 Pathway Commons Protein-Protein Interactions 1.0 null hsa-miR-539 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 GSE74251_2_v_1_decitabine_human RummaGEO Drug Perturbation Signatures 1.0 null VIIIA, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.987804 GTEX-UJHI-1226-SM-4IHLR GTEx Tissue Sample Gene Expression Profiles 1.0 1.83759 CST complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.625 SUZ12_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_SK-N-MC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OXRN-0005-SM-2I5EU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.68241 H3K4me1_CD34 Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null cerebellar cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.847216 GTEX-U8XE-1126-SM-3DB8W GTEx Tissue Sample Gene Expression Profiles -1.0 -0.883779 MDA-MB-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.901347 BRD-K25312635 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.18486 hsa-miR-4484 TargetScan Predicted Conserved microRNA Targets 1.0 1.26663 scoliosis HPO Gene-Disease Associations 1.0 null JUND_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Salivary gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Perturb_5056_OE_MERVL_SRP161512 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -12.8131 GSE186440,GSE186443_1_v_7_daxx_human RummaGEO Gene Perturbation Signatures 1.0 null posteroventral (inferior) parietal cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.34209 H2AFZ_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HDAC2_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null cytoplasmic part LOCATE Curated Protein Localization Annotations 1.0 null ventrolateral prefrontal cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.918346 FLNA Pathway Commons Protein-Protein Interactions 1.0 null YWHAQ Pathway Commons Protein-Protein Interactions 1.0 null Medulloblastoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.497 H3K4me1_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null abnormal hand morphology HPO Gene-Disease Associations 1.0 null H3K4me2_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Endometriosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.274 Tadpole TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.808 POLR2A_limb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_brain microvascular endothelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE242199_9_v_5_ntrk2_human RummaGEO Gene Perturbation Signatures -1.0 null Pancreatic adenocarcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.326 NCIH526 CCLE Cell Line Gene CNV Profiles 1.0 1.8875 Fibroma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.228 ACC3 BioGPS Cell Line Gene Expression Profiles -1.0 -0.833406 Brain Lower Grade Glioma_LGG_TCGA-DU-8158-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AIRE_KO_GDS2274_245_mouse_Medullary thymic epithelial cells (with low CD80 expression) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null perineurium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.336336 myclobutanil LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.37094 H3K4me3_HepG2_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null aplasia/hypoplasia affecting the eye HPO Gene-Disease Associations 1.0 null Eye disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.559 H3K9ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null LNZTA3WT4 DepMap CRISPR Gene Dependency 1.0 2.75721 spontaneous skin ulceration MPO Gene-Phenotype Associations 1.0 null GTEX-V1D1-0003-SM-3NMDP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.27035 GTEX-U3ZN-0226-SM-3DB8D GTEx Tissue Sample Gene Expression Profiles -1.0 -0.845748 UKE-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.2618 TGIF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.09665 molting cycle GO Biological Process Annotations 2015 1.0 null A2780 CCLE Cell Line Gene Mutation Profiles 1.0 null moroxydine-6705 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null EGR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TTF2 ChEA Transcription Factor Targets 1.0 null GSE216043_7_v_2_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null Hyperactive Behavior DisGeNET Gene-Phenotype Associations 1.0 null Uterine epithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.721 spanning component of plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.311478 GTEX-NPJ8-1426-SM-3MJHR GTEx Tissue Sample Gene Expression Profiles 1.0 0.987887 myotome TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.307167 BRD-K48040318 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.07722 GSE182680,GSE182683_7_v_13_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me3_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Dlx4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.8952 MHH-NB-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.858421 Leydig cell_Fetal gonad_Human CellMarker Gene-Cell Type Associations 1.0 null Breast cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.687 H3K4me2_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null regulation of cell growth GO Biological Process Annotations 2023 1.0 null aorta TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.07344 H3K4me3_BJ_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Epidermal cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.927 hsa-miR-497 TargetScan Predicted Conserved microRNA Targets 1.0 0.088999 H3K27ac_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null RKO-E6 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null Perturb_1060_Mut_Esr1_SRP087718 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.18815 GGT7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.20646 congenital nervous system abnormality DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.126937 GSE196699_7_v_3_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CREB3L1_CREB3L1 Rummagene Transcription Factor Associations 2026 1.0 null H3K27ac_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null EFO-27 COSMIC Cell Line Gene Mutation Profiles 1.0 null 9+0 non-motile cilium COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.21 abnormal genital system morphology HPO Gene-Disease Associations 1.0 null NLN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63227 RCH-ACV COSMIC Cell Line Gene Mutation Profiles 1.0 null desmoplastic/nodular medulloblastoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.654 SPHK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.77247 GSE124920_1_v_2_prmt1_mouse RummaGEO Gene Perturbation Signatures 1.0 null HDAC2 ENCODE Transcription Factor Targets 1.0 null intracellular organelle LOCATE Curated Protein Localization Annotations 1.0 null osteochondrodysplasia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.065031 NPM1 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me1_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CL-34 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCI-H128 COSMIC Cell Line Gene Mutation Profiles 1.0 null EZH2 ENCODE Transcription Factor Targets 1.0 null POLR2A_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-44-A4SU-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_B cell_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_HL-60_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_megakaryocyte_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RWSA-2426-SM-47JXR GTEx Tissue Sample Gene Expression Profiles 1.0 1.51103 Myotome TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.46 GTEX-WZTO-1026-SM-3NM9P GTEx Tissue Sample Gene Expression Profiles 1.0 2.14927 H3K4me3_fibroblast of pulmonary artery_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null A2058 CCLE Cell Line Gene Expression Profiles -1.0 -2.447 placenta_3a HPA Tissue Sample Gene Expression Profiles -1.0 -0.930111 H3K4me1_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TAF1 ENCODE Transcription Factor Targets 1.0 null S100A9 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-OIZG-0005-SM-2HMJC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.01384 Clumsiness - Motor Delay DisGeNET Gene-Disease Associations 1.0 null GR-M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.39309 GSE114883_0_v_5_romidepsin_human RummaGEO Drug Perturbation Signatures 1.0 null TMEM82 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61654 carboplatin LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.1132 GCM2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.8531 HPAC cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.577 Thyroid cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.041 CEBPB-21427703-3T3-L1-MOUSE ChEA Transcription Factor Targets 2022 1.0 null UACA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05374 Papillary carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.751 Fibula TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.531 BRD-K49755501 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.0576 H3K27me3_cardiac mesoderm_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null M-1 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.1448 ZR751 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.600847 ChIP_SOX2_18692474 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-4A-A93Y-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.303655 ATR Pathway Commons Protein-Protein Interactions 1.0 null BRD-K42987166 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.12407 Fetal alcohol spectrum disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.056 PMAIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90098 skeletal muscle HPA Tissue Protein Expression Profiles 1.0 0.96344 posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.69545 PMC9529122-pone.0274785.s002.xlsx-S1_Table-S1A_Table_Differentially_expressed_genes_in_HeyA8_overexpressin_ZNF521_vs_HeyA8_control_cells_ZNF521 Rummagene Transcription Factor Associations 2026 1.0 null BECKER COSMIC Cell Line Gene Mutation Profiles 1.0 null IGR-37 COSMIC Cell Line Gene Mutation Profiles 1.0 null CTCF ENCODE Transcription Factor Targets 1.0 null GTEX-RU72-1126-SM-2TF6H GTEx Tissue Sample Gene Expression Profiles 1.0 1.77027 GTEX-RVPV-1226-SM-2TF73 GTEx Tissue Sample Gene Expression Profiles 1.0 0.888542 GTEX-S95S-1126-SM-4B64E GTEx Tissue Sample Gene Expression Profiles 1.0 1.04467 GSE144231_4_v_5_cxcr2_mouse RummaGEO Gene Perturbation Signatures 1.0 null SUZ12 ENCODE Transcription Factor Targets 1.0 null Perturb_5010_KO_Sall4_ERP122174 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 KLF4 ChEA Transcription Factor Targets 1.0 null NCI-H1975 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07599 inner SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.35775 shh GeneRIF Biological Term Annotations 1.0 null Pelvic fin TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.523 NCI-H522 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.72764 PMC4782046-supp_30.5.508_TableS2.xlsx-TAL1_UTX-co-bound_genes-Unnamed_4_TAL1 Rummagene Transcription Factor Associations 2026 1.0 null KMS-28BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.8483 K-562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.07252 meiotic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.360036 PMC6242972-41467_2018_6699_MOESM5_ESM.xlsx-Sheet1-Supplementary_Data_2_Significantly_up-_and_down-regulated_genes_adj_P_Val_0_05_upon_TBX2_knockdown_in_the_IMR-5_75_cell_line_TBX2 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_astrocyte of the cerebellum_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null enlarged spleen MPO Gene-Phenotype Associations 1.0 null NCIH510 CCLE Cell Line Gene Mutation Profiles 1.0 null KDM1A ENCODE Transcription Factor Targets 1.0 null Mesothelioma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.727 H3K27me3_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Squamous cell carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.598 Sox11 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 30.7114 NANOG-21062744-HESC-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null H3K4me3_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null hacat HPA Cell Line Gene Expression Profiles -1.0 -0.915566 CIBAR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49202 primary auditory cortex (core)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.22775 CFL1 Pathway Commons Protein-Protein Interactions 1.0 null DPYSL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85741 MYC ChEA Transcription Factor Targets 1.0 null intellectual disability HPO Gene-Disease Associations 1.0 null GTEX-VUSG-0003-SM-3NMDK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35611 Hair follicle neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.287 ventrolateral prefrontal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.13985 GTEX-N7MS-0225-SM-4E3HO GTEx Tissue Sample Gene Expression Profiles 1.0 1.124 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-11A-13R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE248858_5_v_0_tcpobop_mouse RummaGEO Drug Perturbation Signatures 1.0 null orbital frontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.824961 UBA52 Pathway Commons Protein-Protein Interactions 1.0 null GSE211955_1_v_0_jmjd4_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE119603_1_v_0_oxaliplatin_human RummaGEO Drug Perturbation Signatures 1.0 null Frontal Bossing DisGeNET Gene-Disease Associations 1.0 null PRC1_BMI_UP.V1 MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations -1.0 null WM983B DepMap CRISPR Gene Dependency 1.0 2.2036 BRD-K10087503 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.09029 Colon cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.294 Focal dermal hypoplasia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.593 BE-13 COSMIC Cell Line Gene Mutation Profiles 1.0 null Pancreatic cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.385 abnormal spleen size MPO Gene-Phenotype Associations 1.0 null Spanning component of plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.425 pimethixene LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.84352 connective tissue disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.06878 NCI-H1155 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.48917 GSE140322_0_v_1_imatinib_human RummaGEO Drug Perturbation Signatures 1.0 null abnormality of thumb phalanx HPO Gene-Disease Associations 1.0 null SNU46 DepMap CRISPR Gene Dependency 1.0 3.89301 ARRB2 Pathway Commons Protein-Protein Interactions 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DB-A75P-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CCNT2 ENCODE Transcription Factor Targets 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KC-A4BV-01A-31R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K25638721 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.19062 Taste bud TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.788 TE125T CCLE Cell Line Gene Expression Profiles -1.0 -1.47969 Ciliary membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.81 GTEX-XMD1-0006-SM-4AT4Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03201 SW 1463 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.930262 Intraciliary transport particle A COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.012 BRD-K25573760 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05353 CCDC34 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.48971 PLEKHA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55012 SFN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.12683 BRD-K03542527 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.40647 GTEX-Q2AH-0005-SM-33HBR GTEx Tissue Sample Gene Expression Profiles -1.0 -2.05302 medulloblastoma OMIM Gene-Disease Associations 1.0 null Perturb_13714_KO_ASXL3_SRP360138 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.92963 Neoplasms, Second Primary HuGE Navigator Gene-Phenotype Associations 1.0 null Foot layer COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.807 H2BC6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.66655 integral component of plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.141178 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4337-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Puberty, Precocious CTD Gene-Disease Associations 1.0 1.16368 CRCGN011_HEPG2_24H:I14 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.0804 H2AFZ_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TBX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.1877 GTEX-OHPK-2426-SM-3MJGH GTEx Tissue Sample Gene Expression Profiles 1.0 1.02409 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3HZ-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null outer CP in midlateral extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.28245 CL11 CCLE Cell Line Gene Expression Profiles -1.0 -1.56187 MXI1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null regulation of signal transduction GO Biological Process Annotations 2015 1.0 null GTEX-XPVG-0826-SM-4B654 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.911589 caudal (posterior) extramural migratory stream Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.977678 mRNA_MYOD1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null NCI-H929 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.828629 PMC10591418-12711_2023_849_MOESM11_ESM.xls-AA_E10_vs_LS_E10-gene_name_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me1_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null 46,XY sex reversal 7 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.091 Pancreatic ductal adenocarcinoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.856 spontaneous skin ulceration MGI Mouse Phenotype Associations 2023 1.0 null hsa-miR-4709-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 Perturb_7921_OE_HLAG_SRP386250 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Bone sarcoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.159 Crus II, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.04419 Lung adenocarcinoma_LUAD_TCGA-38-A44F-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ELF1 ENCODE Transcription Factor Targets 1.0 null POU5F1-18700969-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-R55E-2726-SM-48FCX GTEx Tissue Sample Gene Expression Profiles 1.0 1.15414 Horizontal cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.905 cellular bud COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.543176 GSE101767_1_v_0_wdr11_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_endothelial cell of umbilical vein_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null TTC38 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48593 BRD-K09308989 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.1609 Choline CTD Gene-Chemical Interactions 1.0 null GSE151782_6_v_7_aim2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-XBEW-0006-SM-4AT4E GTEx Tissue Sample Gene Expression Profiles -1.0 -1.79917 GSE112860_5_v_4_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null Coloboma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.904 ASPC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.57747 Endocrine system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.045 localized skin lesion HPO Gene-Disease Associations 1.0 null MCF10F Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.94245 Spina bifida occulta DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.14 Septum pellucidum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.961 midbrain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.109838 epidermis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.65543 Ubiquinone biosynthesis complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.843 HCC1806 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.700877 outer portion of medial ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.980675 SARS-CoV MA15_Day2-PFU-10^5_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.50913 GTEX-SIU7-0006-SM-2XCE6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.2737 ESC_J1_UP_LATE.V1 MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations -1.0 null H3K4me3_epithelial cell of esophagus_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-N7MS-0526-SM-4E3JP GTEx Tissue Sample Gene Expression Profiles 1.0 2.0931 BRD-K84707727 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.00819 photoreceptor TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.379499 Proboscis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.73 HCC2688 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.852229 Lung adenocarcinoma_LUAD_TCGA-97-A4M5-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Metatarsal bone TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.686 LPCAT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.0766 cell type cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.555956 TEAD4 ENCODE Transcription Factor Targets 1.0 null GTEX-R3RS-0008-SM-48FF1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11017 Prostate adenocarcinoma_PRAD_TCGA-KK-A7AZ-01A-12R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-PVOW-0626-SM-2XCF6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.84137 PMC3720582__F2 PFOCR Pathway Figure Associations 2024 1.0 null H3K27me3_MEL cell line_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null UPCISCC200 DepMap CRISPR Gene Dependency 1.0 3.02028 CTV-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null INA Pathway Commons Protein-Protein Interactions 1.0 null GTEX-XPT6-0126-SM-4B65S GTEx Tissue Sample Gene Expression Profiles -1.0 -0.852201 IGROV-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-POYW-0008-SM-48TE4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.18196 BRD-K09871160 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.10473 GTEX-XYKS-1726-SM-4E3IO GTEx Tissue Sample Gene Expression Profiles 1.0 1.53052 GSE70499_5_v_1_bmal1_mouse RummaGEO Gene Perturbation Signatures -1.0 null 42-MG-BA COSMIC Cell Line Gene Mutation Profiles 1.0 null SF295 GDSC Cell Line Gene Expression Profiles -1.0 -1.8327 GSE247764_4_v_2_nell2_mouse RummaGEO Gene Perturbation Signatures 1.0 null YY1 ENCODE Transcription Factor Targets 1.0 null genital neoplasm HPO Gene-Disease Associations 1.0 null Scapula TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.844 perichondrium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.241746 Muscular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.659 PMC5867295__F3 PFOCR Pathway Figure Associations 2023 1.0 null GTEX-XLM4-1526-SM-4AT6D GTEx Tissue Sample Gene Expression Profiles 1.0 1.37405 GTEX-P4QR-0006-SM-2I5GN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.19366 SK-MEL-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.1449 Perturb_13256_KD_Phf5a_SRP083772 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 8.24941 Irf1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 34.6932 H3K9ac_Skeletal Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K30581008 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.31501 DETROIT 562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.98773 neuroectodermal tumor DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.09545 dorsolateral prefrontal cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.03399 PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context3-Gene_Name_ATF3 Rummagene Transcription Factor Associations 2026 1.0 null Connective tissue cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.335 MLX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.05476 PIK3R2 Pathway Commons Protein-Protein Interactions 1.0 null SLC35B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02703 Intercellular bridge COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.658 cerebellar cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.35113 GTEX-X8HC-0006-SM-46MV6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35778 PMC7346528__F1 PFOCR Pathway Figure Associations 2023 1.0 null PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_6_MRC-Gene_FOXK2 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-R3RS-0005-SM-3GAEH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.2844 GTEX-SE5C-0006-SM-4BRW5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.37581 RNF215 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.60653 SRRM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.35433 SIN3B-21632747-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Esophagus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 parietal bossing HPO Gene-Disease Associations 1.0 null Skeletal muscle TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 odontogenic neoplasm HPO Gene-Disease Associations 1.0 null H3K27me3_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K36465335 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.53316 Cowden syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.031 RAD21_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-Y8E5-0006-SM-47JWQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.58186 TUBB2A Pathway Commons Protein-Protein Interactions 1.0 null Brain cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.493 HDAC2_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7X8-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE213228_1_v_5_irak2_human RummaGEO Gene Perturbation Signatures 1.0 null SALL4-18804426-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Perturb_14693_KO_Sufu/Spop_SRP171166 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null HEY DepMap CRISPR Gene Dependency 1.0 2.20622 UACC893 CCLE Cell Line Gene Mutation Profiles 1.0 null PrefrontalCortex BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.09033 Odontogenic Tumors HuGE Navigator Gene-Phenotype Associations 1.0 null RBM6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.6727 bud TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.67821 CREB1 ENCODE Transcription Factor Targets 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NC-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null negative regulation of signal transduction GO Biological Process Annotations 2023 1.0 null CRCGN015_MCF10A.TP53.M_24H:J07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.8406 SW684 COSMIC Cell Line Gene Mutation Profiles 1.0 null BRD-K51666223 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.64878 KLF4-18555785-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.770435 GTEX-S4Q7-0008-SM-3NM8A GTEx Tissue Sample Gene Expression Profiles -1.0 -0.832413 GTEX-PWCY-1426-SM-48TCT GTEx Tissue Sample Gene Expression Profiles 1.0 1.17308 Bronchial bud TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.856 Abnormalities, Drug-Induced CTD Gene-Disease Associations 1.0 1.24465 Polydactyly DisGeNET Gene-Disease Associations 1.0 null GTEX-N7MS-2625-SM-3LK77 GTEx Tissue Sample Gene Expression Profiles 1.0 0.941291 cardiovascular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052389 Malignant exocrine pancreas neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.378 BRD-K72915114 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.18001 H3K4me3_fibroblast of the aortic adventitia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CRCGN017_MCF10A.WT.HP_24H:F11 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.1246 CD33+_Myeloid BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.945385 NCI-H727 GDSC Cell Line Gene Expression Profiles -1.0 -1.45192 Brn3a_KO_GDS1651_248_mouse_Embryonic (day 13.5) trigeminal ganglia - homozygous GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A49I-01A-12R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cranium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.423054 ATP5B Pathway Commons Protein-Protein Interactions 1.0 null Carcinoma, Basal Cell DisGeNET Gene-Disease Associations 1.0 null oropharynx TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.314772 FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null PMC7696523__F1 PFOCR Pathway Figure Associations 2023 1.0 null BRD-K80602847 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.21659 Down-Sloping Shoulders DisGeNET Gene-Phenotype Associations 1.0 null H3K27ac_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Sarcoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.769 PMC7921413-41467_2021_21650_MOESM5_ESM.xlsx-002_DE-CD34_Blasts_AP1_high_JUN Rummagene Transcription Factor Associations 2026 1.0 null YY1_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null KP4 CCLE Cell Line Gene Mutation Profiles 1.0 null abnormality of the globe HPO Gene-Disease Associations 1.0 null POLR2A_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null DMD Pathway Commons Protein-Protein Interactions 1.0 null SET-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.74463 GSE203308_7_v_5_brf1_mouse RummaGEO Gene Perturbation Signatures -1.0 null preoptic BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.72553 BRD-K59087082 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.68132 H3K4me2_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE226584,GSE226589_2_v_0_ezh2_human RummaGEO Gene Perturbation Signatures 1.0 null Perturb_5141_KO_Rn7sk_ERP002405 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 11.2957 BRD-K91952416 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.39844 GTEX-XOTO-0326-SM-4B66K GTEx Tissue Sample Gene Expression Profiles 1.0 1.91912 Anther TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.281 CPA1 Pathway Commons Protein-Protein Interactions 1.0 null reported GeneRIF Biological Term Annotations 1.0 null RPMI 2650 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.90999 Melanocytic Nevus DisGeNET Gene-Disease Associations 1.0 null HCC-366 COSMIC Cell Line Gene Mutation Profiles 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5J5-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null QGP-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Cleft Palate DisGeNET Gene-Disease Associations 1.0 null CALU-6 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.072 BRD-K24815102 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.36589 K-562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.934329 STAT5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.20972 H3K4me3_fibroblast of skin of abdomen_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Oviduct TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 U2SURP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7183 GTEX-WHWD-2326-SM-3LK6Q GTEx Tissue Sample Gene Expression Profiles 1.0 0.946436 Hedgehog signaling WikiPathways Pathways 2024 1.0 null Prostate adenocarcinoma_PRAD_TCGA-YL-A8SH-01B-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Well Differentiated Oligodendroglioma DisGeNET Gene-Disease Associations 1.0 null extramedullary hematopoiesis MPO Gene-Phenotype Associations 1.0 null Bone marrow stromal stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.664 H3K27me3_cardiac mesoderm_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null endometrium_5a HPA Tissue Sample Gene Expression Profiles 1.0 0.913811 TUBA1C Pathway Commons Protein-Protein Interactions 1.0 null Ovary epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.887 Checkpoint clamp complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.639 membrane LOCATE Curated Protein Localization Annotations 1.0 null PMC6473842__F2 PFOCR Pathway Figure Associations 2024 1.0 null KLF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 86.5988 EFM-192B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.35585 GTEX-PWOO-0006-SM-2I3E3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.38238 abnormality of the vertebrae HPO Gene-Disease Associations 1.0 null Thyroid gland adenocarcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.467 Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RF-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_10767_KO_Nrf2_SRP311380 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.65197 GSE248858_6_v_2_tcpobop_mouse RummaGEO Drug Perturbation Signatures 1.0 null Kyphoscoliosis Deformity Of Spine DisGeNET Gene-Disease Associations 1.0 null SNU-81 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-WVLH-3126-SM-3MJGA GTEx Tissue Sample Gene Expression Profiles 1.0 0.883584 GSE147669_2_v_1_tram2_human RummaGEO Gene Perturbation Signatures 1.0 null KCL22 CCLE Cell Line Gene Mutation Profiles 1.0 null NFYB-21822215-K562-HUMAN ChEA Transcription Factor Targets 2022 1.0 null DMS 273 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.28006 GSE181517_0_v_1_doxorubicin_human RummaGEO Drug Perturbation Signatures 1.0 null multiform (lateral) division of MD Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.76285 hamartoma HPO Gene-Disease Associations 1.0 null Childhood Neuroblastoma DisGeNET Gene-Disease Associations 1.0 null H3K9ac_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null hedgehog GeneRIF Biological Term Annotations 1.0 null GTEX-NPJ7-2926-SM-3MJGQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.88996 ZEB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.488 GTEX-X5EB-2026-SM-4E3KA GTEx Tissue Sample Gene Expression Profiles 1.0 1.10416 musculoskeletal system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.051167 BRD-K75900905 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.13718 RCM1 CCLE Cell Line Gene Mutation Profiles 1.0 null Primordium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.587 GSE226316_3_v_2_tead2_mouse RummaGEO Gene Perturbation Signatures -1.0 null BRD-K40565784 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.90727 Perturb_814_KD_Dnmt3a_SRP119259 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 PLPP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.20087 abnormality of limb bone HPO Gene-Disease Associations 1.0 null abnormal myeloid leukocyte morphology MPO Gene-Phenotype Associations 1.0 null Crus I, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.46159 NCI H226 BioGPS Cell Line Gene Expression Profiles -1.0 -2.08177 DGKG Pathway Commons Protein-Protein Interactions 1.0 null JEG3 DepMap CRISPR Gene Dependency 1.0 3.27097 NCI-H1355 COSMIC Cell Line Gene Mutation Profiles 1.0 null malignant neoplasm of the central nervous system HPO Gene-Disease Associations 1.0 null H3K4me1_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-4441 TargetScan Predicted Conserved microRNA Targets 1.0 0.90397 MGAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69245 cardiovascular system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.049458 greig cephalopolysyndactyly syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.801154 cerebral calcification HPO Gene-Disease Associations 1.0 null sense organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.283191 H3K4me1_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null RPS2 Pathway Commons Protein-Protein Interactions 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HI-7168-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null female reproductive organ benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.263014 Archenteron TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.663 JUND ENCODE Transcription Factor Targets 1.0 null inner SZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.72071 CRBN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.40974 GTEX-PLZ6-0006-SM-33HBZ GTEx Tissue Sample Gene Expression Profiles -1.0 -3.92086 BRD-K40964045 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.17688 glimepiride-2809 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.356 Nervous system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.315 Lymphatic system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.413 Utricle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.721 TLCD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.13877 GTEX-WHSE-0006-SM-3NMBW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.22763 signal transducer activity GO Molecular Function Annotations 2015 1.0 null NCI-H2722 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.02597 H3K9ac_Pancreatic Islets Roadmap Epigenomics Histone Modification Site Profiles 1.0 null YES1 Pathway Commons Protein-Protein Interactions 1.0 null GSE161295_2_v_5_cdk8_mouse RummaGEO Gene Perturbation Signatures 1.0 null Greig cephalopolysyndactyly syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.362 BRD-K79103937 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.31626 GTEX-RWSA-0008-SM-47JYX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.29238 GSE238018_1_v_4_mxra8_human RummaGEO Gene Perturbation Signatures 1.0 null PRKD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.09689 L428 CCLE Cell Line Gene Mutation Profiles 1.0 null aplasia/hypoplasia involving the skeleton HPO Gene-Disease Associations 1.0 null GTEX-S7PM-0008-SM-3NM9Q GTEx Tissue Sample Gene Expression Profiles -1.0 -0.987439 abnormality of the intestine HPO Gene-Disease Associations 1.0 null H3K4me3_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A6DV-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K85546819 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.44283 abnormal axial skeleton morphology HPO Gene-Disease Associations 1.0 null Telencephalon TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 ethisterone-3864 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q8-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RASopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.269 SW 1116 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.856103 DNA polymerase III complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.745 abnormality of the upper limb HPO Gene-Disease Associations 1.0 null BRD-K06956443 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.63181 Perturb_5013_KO_Sall4_ERP122174 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 GSE146074_9_v_8_ly6e_mouse RummaGEO Gene Perturbation Signatures 1.0 null CCDC127 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.19341 NCI-H727 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.916999 KPNYN CCLE Cell Line Gene CNV Profiles -1.0 -1.94381 NCI-H1435 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.44498 intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null posterior group of nuclei, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.23247 aplasia involving bones of the extremities HPO Gene-Disease Associations 1.0 null GTEX-UPK5-0006-SM-3GAD8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.37235 Malignant ovarian surface epithelial-stromal neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.084 FOSL2 ENCODE Transcription Factor Targets 1.0 null GTEX-UTHO-2926-SM-3P5Z9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.22461 POU5F1 ChEA Transcription Factor Targets 1.0 null Disease Models, Animal CTD Gene-Disease Associations 1.0 1.15189 PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC Rummagene Transcription Factor Associations 2026 1.0 null heart GTEx Tissue Gene Expression Profiles -1.0 -0.918561 CACNG7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97043 H3K4me3_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K64827406 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.34675 Signaling events mediated by the Hedgehog family PID Pathways 1.0 null PFSK-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-97-8172-01A-11R-2287-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE198165,GSE198166_9_v_4_zfp266_mouse RummaGEO Gene Perturbation Signatures 1.0 null primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.07772 leiomyomatosis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.463527 SPTAN1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-XGQ4-0004-SM-4AT5S GTEx Tissue Sample Gene Expression Profiles -1.0 -1.33217 GSE121809_1_v_0_fmr1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-TML8-1626-SM-32QOO GTEx Tissue Sample Gene Expression Profiles 1.0 1.20881 abnormal skin morphology MPO Gene-Phenotype Associations 1.0 null hsa-miR-198 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 PMC10253447__F2 PFOCR Pathway Figure Associations 2024 1.0 null Epithelial stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.132 abnormality of globe size HPO Gene-Disease Associations 1.0 null MEX3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.26568 posteroventral (inferior) parietal cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.909841 GSE248858_1_v_2_tcpobop_mouse RummaGEO Drug Perturbation Signatures 1.0 null mRNA_CDX2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Multiple endocrine neoplasia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.523 short finger HPO Gene-Disease Associations 1.0 null connective tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.524771 skin lesions MGI Mouse Phenotype Associations 2023 1.0 null HBS1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.67484 macrocephaly HPO Gene-Disease Associations 1.0 null Central nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.09 GTEX-O5YU-0008-SM-4E3I7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.884769 Perturb_16467_KO_Ncstn_SRP149348 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.66415 SOX2-18692474-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null Pollen mother cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.92 KYSE270 DepMap CRISPR Gene Dependency 1.0 2.1979 BRD-K25119693 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.13521 abnormality of nervous system physiology HPO Gene-Disease Associations 1.0 null BRD-K29684372 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.45583 posteroventral (inferior) parietal cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.33444 EIF4B Pathway Commons Protein-Protein Interactions 1.0 null PMC5795782-supp_gad.302646.117_Supplemental_Table_S1.xlsx-Table_S1_2-Supplemental_Table_S1_2_Genes_significantly_upregulated_by_ARID5B_knockdown_ARID5B Rummagene Transcription Factor Associations 2026 1.0 null Papillary Thyroid Carcinoma DisGeNET Gene-Disease Associations 1.0 null GSE110178_2_v_0_tranylcypromine_mouse RummaGEO Drug Perturbation Signatures 1.0 null H3K9ac_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null urogenital system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.760328 egg TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.115956 Kidney Chromophobe_KICH_TCGA-KL-8336-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null neuroepithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.300679 PNMA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.33087 synostosis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.139523 ZBTB7A_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null B-cell lymphoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.095 MDAMB453 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.37933 GTEX-R55C-0008-SM-48FCF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.832548 BRD-K94573433 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.17011 bupropion-6256 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null abnormal bone marrow cell number MGI Mouse Phenotype Associations 2023 1.0 null HT55 DepMap CRISPR Gene Dependency 1.0 2.81472 hair TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.147014 SP9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.07507 GTEX-Q2AG-0005-SM-33HBX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.71739 autosomal dominant inheritance HPO Gene-Disease Associations 1.0 null P4HB Pathway Commons Protein-Protein Interactions 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-7728-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K89514545 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.10099 Hair follicle bulge stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.464 UBE2S CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.00151 Class B/2 (Secretin family receptors) Reactome Pathways 2014 1.0 null GTEX-XPVG-0006-SM-4B65Z GTEx Tissue Sample Gene Expression Profiles -1.0 -1.38705 TCF12 ENCODE Transcription Factor Targets 1.0 null abnormal erythropoiesis MPO Gene-Phenotype Associations 1.0 null PMC5903287-NIHMS956886-supplement-Table_2.xls-THP1_THP2_cds_exp_down-gene_GLI2 Rummagene Transcription Factor Associations 2026 1.0 null eye disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.047596 H3K4me3_fibroblast of gingiva_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K9ac_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null pulmonary valve disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.483985 Abnormality Of The Sense Of Smell DisGeNET Gene-Phenotype Associations 1.0 null spermatid TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.314772 JEKO1 CCLE Cell Line Gene Mutation Profiles 1.0 null testis_7d HPA Tissue Sample Gene Expression Profiles 1.0 1.19993 KCL-22 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-SNMC-1026-SM-4DM7K GTEx Tissue Sample Gene Expression Profiles 1.0 1.61837 Perichondrium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.3 MAP3K1 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me1_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTNNB_Activation (deltaNB-cateninER transgenics)_GDS1560_768_mouse_Skin - 7 Day GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null skeletalmuscle_e HPA Tissue Sample Gene Expression Profiles -1.0 -0.939047 ovarian follicle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.11299 HCC2998 GDSC Cell Line Gene Expression Profiles 1.0 1.4531 plasma membrane LOCATE Predicted Protein Localization Annotations 1.0 null RMG-II cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.545 testis_7e HPA Tissue Sample Gene Expression Profiles 1.0 0.990862 Oral mucosa TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Tooth enamel TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.004 GSE137177_2_v_0_folic acid_mouse RummaGEO Drug Perturbation Signatures -1.0 null Adenoid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.981 H3K27me3_H7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormal spleen morphology MPO Gene-Phenotype Associations 1.0 null NCI-H510A COSMIC Cell Line Gene Mutation Profiles 1.0 null BOP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.84631 H3K4me3_SK-N-MC_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null NCI-H1355 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.0303 GTEX-PWO3-0005-SM-2I5FS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.73505 BRD-K74755318 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.88471 BRD-K09583061 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.02585 cell type benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.069588 Disease by infectious agent DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.132 GSE213442_1_v_0_kpna2_mouse RummaGEO Gene Perturbation Signatures 1.0 null DGKH Pathway Commons Protein-Protein Interactions 1.0 null GSE120612_4_v_5_etoposide_human RummaGEO Drug Perturbation Signatures -1.0 null ARMC7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.34872 Cognition Disorders CTD Gene-Disease Associations 1.0 1.27875 orbital frontal cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.851859 primary auditory cortex (core)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.7217 GTEX-NL3H-0011-R11A-SM-2I3E6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.09624 H3K27ac_CD4 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null FBXL5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.54806 GSE145323,GSE145324_1_v_4_rfx3_mouse RummaGEO Gene Perturbation Signatures 1.0 null IZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.80137 BRD-K10144853 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.18962 CRCGN015_MCF10A.WT.HP_24H:C21 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.3926 PMC7888619-pgen.1009309.s032.xlsx-S9_Table-S9_Table_Predicted_target_genes_of_POU3F2_POU3F2 Rummagene Transcription Factor Associations 2026 1.0 null ZNF143 ENCODE Transcription Factor Targets 1.0 null GSN Pathway Commons Protein-Protein Interactions 1.0 null GSE137177_1_v_4_folic acid_mouse RummaGEO Drug Perturbation Signatures -1.0 null Mucosa TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 BRD-K33456231 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.68181 CTCFL JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.4179 KASUMI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.59156 t60-adrenal_consensus MoTrPAC Rat Endurance Exercise Training 1.0 2.1073 posterior (caudal) superior temporal cortex (area 22c)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.28192 fibroma HPO Gene-Disease Associations 1.0 null BRD-K00611112 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.63569 GSE196699_7_v_6_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null orbital frontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.42507 Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A8OD-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CHD2 ENCODE Transcription Factor Targets 1.0 null GSE162892_4_v_2_sox9_human RummaGEO Gene Perturbation Signatures 1.0 null SIN3B ChEA Transcription Factor Targets 1.0 null bone TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.277197 BRD-K13069055 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.28137 ME-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Muscle tendon junction COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.643 GSE120612_7_v_0_etoposide_human RummaGEO Drug Perturbation Signatures 1.0 null PMC4029299__F3 PFOCR Pathway Figure Associations 2024 1.0 null Autonomic nervous system neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.074 BRD-K26395018 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.84375 inferolateral temporal cortex (area TEv, area 20)_11 yrs_F_12289 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.6431 H3K4me3_cardiac mesoderm_hg19_5 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_Panc1_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-RNOR-0326-SM-2TF51 GTEx Tissue Sample Gene Expression Profiles 1.0 2.34082 ovary_6a HPA Tissue Sample Gene Expression Profiles 1.0 0.974151 RPS8 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K34028745 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.01461 autosomal recessive disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.078458 CDC73 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44935 GTEX-XUJ4-1326-SM-4BOQ9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.16173 hedgehog signaling pathway KEGG Pathways 1.0 null ACTBL2 Pathway Commons Protein-Protein Interactions 1.0 null skin carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.28959 abnormality of the dura mater HPO Gene-Disease Associations 1.0 null Perturb_13717_KO_BAP1_SRP360138 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.91088 GSE226316_0_v_2_tead2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-PWCY-0005-SM-33HBP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.93501 Chronic Myeloproliferative Disorder DisGeNET Gene-Disease Associations 1.0 null neoplasm of striated muscle HPO Gene-Disease Associations 1.0 null COLO775 CCLE Cell Line Gene Expression Profiles 1.0 2.69123 Olfactory placode TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.941 H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DB-A64O-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U3ZM-0002-SM-3NMDM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.39394 CIA complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.615 lateral hypothalamic area, anterior region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.24543 GTEX-QESD-1726-SM-2S1R7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.94487 GTEX-UPIC-0002-SM-3NMDC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.01593 abnormality of the lens HPO Gene-Disease Associations 1.0 null GSE145215_0_v_3_krt13_mouse RummaGEO Gene Perturbation Signatures 1.0 null hippocampus (hippocampal formation)_8 yrs_M_12981 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.28283 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4355-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mo-b cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.57082 posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.77962 GSE145323,GSE145324_3_v_2_rfx3_mouse RummaGEO Gene Perturbation Signatures -1.0 null GNA13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.48519 GTEX-OOBJ-2126-SM-3NB1N GTEx Tissue Sample Gene Expression Profiles 1.0 1.35598 Atrophy CTD Gene-Disease Associations 1.0 1.51936 Stomach disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.471 GSE198165,GSE198166_0_v_3_zfp266_mouse RummaGEO Gene Perturbation Signatures -1.0 null KMS20 CCLE Cell Line Gene CNV Profiles -1.0 -1.73142 GSE92614_1_v_0_pten_mouse RummaGEO Gene Perturbation Signatures -1.0 null Renal carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.077 cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.497826 TCF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.0155 Thyroid gland anaplastic carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.344 Lymphoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.393 Limb bud TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.867 Perturb_4316_KO_Ror2_SRP292420 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 7.95969 GSE223609,GSE223610_0_v_2_kdm6a_human RummaGEO Gene Perturbation Signatures 1.0 null LIMA1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-R45C-0008-SM-48FF2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.873647 EVSAT CCLE Cell Line Gene Mutation Profiles 1.0 null RCOR3 ChEA Transcription Factor Targets 1.0 null SNU81 CCLE Cell Line Gene Mutation Profiles 1.0 null H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null globose nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.38345 fenoprofen-3612 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-XQ8I-0006-SM-4BOQ5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.39234 testis_7f HPA Tissue Sample Gene Expression Profiles 1.0 1.61928 abnormal bone ossification HPO Gene-Disease Associations 1.0 null organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.337373 lysosome LOCATE Predicted Protein Localization Annotations 1.0 null H3K4me1_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Smith-Lemli-Opitz syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.106 GTEX-OOBK-0005-SM-2YUMG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.19111 Esophageal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.138 IZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.05053 decreased hematocrit MPO Gene-Phenotype Associations 1.0 null mRNA_SFPI1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null CCDC66 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.03966 tibia TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.213471 developmental disorder of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.051571 H3K4me3_SK-N-SH_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null anterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.65226 IV, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.10174 SOX2-21211035-LN229_GBM-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GPRASP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78671 NCIH1299 CCLE Cell Line Gene Expression Profiles 1.0 1.49614 EGR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-97-7941-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Medulloblastoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.413 CDC42EP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.38811 HT-144 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.901347 guanadrel-3698 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null optic cup TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.378748 GSE112763,GSE112767_0_v_1_dgcr8_mouse RummaGEO Gene Perturbation Signatures 1.0 null NH6 CCLE Cell Line Gene CNV Profiles -1.0 -1.76975 GTEX-WEY5-0006-SM-3GIKG GTEx Tissue Sample Gene Expression Profiles -1.0 -3.10561 abnormality of the eye HPO Gene-Disease Associations 1.0 null H3C4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.20456 pituitary GTEx Tissue Gene Expression Profiles 1.0 0.947665 H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-WCDI-0008-SM-47JYE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04358 abnormal granulocyte number MPO Gene-Phenotype Associations 1.0 null LCMT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99876 GSE180200,GSE180201_15_v_9_qpctl_mouse RummaGEO Gene Perturbation Signatures 1.0 null CPC-N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.33816 BRD-K04834648 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.37327 GSE179880_10_v_13_e2f4_mouse RummaGEO Gene Perturbation Signatures -1.0 null PREPL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.44561 SREBP1-19666523-LIVER-FROM-C57BL-MICE-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null NFI-21473784-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null PMC5807095__F3 PFOCR Pathway Figure Associations 2024 1.0 null GSE189683_3_v_0_rif1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-WRHK-0005-SM-3MJF5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.17755 H2AFZ_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SOX2-18692474-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GTEX-R55E-0826-SM-2TC5M GTEx Tissue Sample Gene Expression Profiles 1.0 1.07533 H3K4me3_Panc1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE180200,GSE180201_15_v_1_qpctl_mouse RummaGEO Gene Perturbation Signatures 1.0 null Urinary system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.554 Skin BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.80874 Pancreatic ductal adenocarcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.224 GTEX-SSA3-0526-SM-32QPL GTEx Tissue Sample Gene Expression Profiles 1.0 2.61679 GTEX-Q734-0726-SM-48TZP GTEx Tissue Sample Gene Expression Profiles 1.0 2.05995 EVSA-T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13484 GSE211151_1_v_4_progesterone_human RummaGEO Drug Perturbation Signatures -1.0 null HMGN3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A5ZZ-01A-31R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Ciliopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.366 A2780 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.901779 BRD-K20026212 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.41153 GTEX-SIU8-0226-SM-2XCDS GTEx Tissue Sample Gene Expression Profiles 1.0 1.13081 GTEX-V955-1926-SM-4KL1L GTEx Tissue Sample Gene Expression Profiles 1.0 1.75717 BRD-K18623962 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.14832 Perturb_1738_KO_Arid2_SRP300754 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.80721 H3K4me2_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Breast carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.17 site of polarized growth COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.123377 H3K4me3_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null 15525570-SuppTable1 GeneSigDB Published Gene Signatures 1.0 null HMGN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27428 H3K4me3_fibroblast of lung_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.09509 H3K27ac_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.934329 Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3YL-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-UPIC-1526-SM-4IHLU GTEx Tissue Sample Gene Expression Profiles 1.0 1.03106 TLX1_01_246 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 0.77169 DorsalRootGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.864755 Prostate adenocarcinoma_PRAD_TCGA-KC-A4BR-01A-32R-A32Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH322 CCLE Cell Line Gene Expression Profiles 1.0 1.855 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3317-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-OXRP-0006-SM-2I3FN GTEx Tissue Sample Gene Expression Profiles -1.0 -2.44366 SPPL2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38771 GSE131887_1_v_3_doxycycline_mouse RummaGEO Drug Perturbation Signatures -1.0 null Skin carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.795 SP4 ENCODE Transcription Factor Targets 1.0 null GSE120413,GSE120447_0_v_1_bap1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Cardiac muscle TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 KMS28BM CCLE Cell Line Gene CNV Profiles -1.0 -1.98547 tretinoin_homo sapiens_gpl6244_gds4180 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null CORL47 CCLE Cell Line Gene Expression Profiles 1.0 1.3734 epidermis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.937994 ANXA9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32305 YBX1 Pathway Commons Protein-Protein Interactions 1.0 null neoplasm HPO Gene-Disease Associations 1.0 null cellular_component LOCATE Curated Protein Localization Annotations 1.0 null PMC6668073__F4 PFOCR Pathway Figure Associations 2024 1.0 null PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-2n_h-r_CIC Rummagene Transcription Factor Associations 2026 1.0 null STXBP5 Pathway Commons Protein-Protein Interactions 1.0 null ELOVL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.13211 GM97 BioGPS Cell Line Gene Expression Profiles 1.0 1.67431 BRD-K77953978 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.47412 CHD4 ENCODE Transcription Factor Targets 1.0 null Congenital Epicanthus DisGeNET Gene-Disease Associations 1.0 null GTEX-P4QS-2126-SM-3NMCF GTEx Tissue Sample Gene Expression Profiles 1.0 1.25889 blastomere TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.075317 polymorphic layer of rostral subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03912 malignant glioma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.064598 reproductive organ cancer GWASdb SNP-Disease Associations 1.0 0.226573 Cardiovascular system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 H3K27me3_megakaryocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TP53-22127205-IMR90-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Nexine COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.903 H3K4me3_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SHH Pathway Commons Protein-Protein Interactions 1.0 null GTEX-XMD3-2326-SM-4AT5H GTEx Tissue Sample Gene Expression Profiles 1.0 1.42694 SW 403 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.16509 Leptomeninx TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.783 SN12C COSMIC Cell Line Gene Mutation Profiles 1.0 null CAL78 CCLE Cell Line Gene CNV Profiles 1.0 1.34401 Perturb_9782_KD_Esrrb_SRP321923 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.64056 H3K4me3_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-S7PM-0626-SM-4AD4Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.3976 GTEX-SN8G-0001-SM-3NM8L GTEx Tissue Sample Gene Expression Profiles -1.0 -1.17139 intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null Hair shaft TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.256 GTEX-X585-0011-R11B-SM-46MUZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.03144 H3K9ac_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ventral midbrain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.373868 UBF1/2-26484160-CHIP-SEQ-HMEC-DERIVED-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Genetic Predisposition to Disease HuGE Navigator Gene-Phenotype Associations 1.0 null CAOV3 CCLE Cell Line Gene CNV Profiles 1.0 1.38386 RKO CCLE Cell Line Gene Expression Profiles 1.0 1.41522 blood cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.059002 GSE129287_0_v_1_cd200_mouse RummaGEO Gene Perturbation Signatures -1.0 null hsa-miR-548am TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 Perturb_5279_OE_Mnx1_ERP140947 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.95784 intermediate portion of DFC (area 9/46) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.829797 GTEX-XQ3S-2726-SM-4BOP2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.60636 MMS19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.9617 POLR2AphosphoS5_neural cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null dermal hyperplasia MGI Mouse Phenotype Associations 2023 1.0 null Leukocytosis DisGeNET Gene-Phenotype Associations 1.0 null BRD-K16705434 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.30436 Perturb_270_KO_ADIRFAS786_SRP366780 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.99383 CPEB4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.32933 isoforms GeneRIF Biological Term Annotations 1.0 null KNS42 DepMap CRISPR Gene Dependency 1.0 3.21746 Arachnoid mater TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.682 Respiratory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.614 OE-33 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.805 Acute Myeloid Leukemia_LAML_TCGA-AB-2832-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Luteal cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.647 Brain Lower Grade Glioma_LGG_TCGA-HT-7860-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cartilage-hair hypoplasia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.321 Pectoral fin TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.448 mnng/hos TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.601 Intraocular pressure GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.1699 CRCGN014_HEPG2_3H:K01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.0198 abnormality of the orbital region HPO Gene-Disease Associations 1.0 null SPSB1 Hub Proteins Protein-Protein Interactions 1.0 null GTEX-WL46-0126-SM-3TW8I GTEx Tissue Sample Gene Expression Profiles 1.0 1.19094 orbital frontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.43468 Molaris TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.082 GSE133213_6_v_15_znrf3_mouse RummaGEO Gene Perturbation Signatures -1.0 null missense GeneRIF Biological Term Annotations 1.0 null abnormal neutrophil morphology MPO Gene-Phenotype Associations 1.0 null 496100395_TCx_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.24381 HS 255.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.05844 anemia MGI Mouse Phenotype Associations 2023 1.0 null HM7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.09884 TBL1-22424771-293T-HUMAN ChEA Transcription Factor Targets 2022 1.0 null limb bud TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.667622 BRD-K84693638 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05892 KARPAS-45 COSMIC Cell Line Gene Mutation Profiles 1.0 null SUP-T1 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_Penis Foreskin Fibroblast Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K97224540 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.3613 ROS50 DepMap CRISPR Gene Dependency 1.0 3.44833 H3K4me3_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null cytoplasmic membrane-bounded vesicle LOCATE Curated Protein Localization Annotations 1.0 null XRN2 ChEA Transcription Factor Targets 1.0 null GSE87615_1_v_3_ascl1_human RummaGEO Gene Perturbation Signatures 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A708-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K43484052 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.34062 H3K4me3_astrocyte of the spinal cord_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null lipid metabolism disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.084284 BRD-K12604570 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.2135 D-542MG COSMIC Cell Line Gene Mutation Profiles 1.0 null JURKAT DepMap CRISPR Gene Dependency 1.0 4.44447 TNKS_INHIBITION_GDS5029_281_human_SW480 KRAS-mutant colorectal cancer cell line - 16hours GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null AN3-CA GDSC Cell Line Gene Expression Profiles -1.0 -1.57952 Broad Face DisGeNET Gene-Phenotype Associations 1.0 null CRCGN008_HEPG2_24H:G17 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.0073 SH10TC CCLE Cell Line Gene Mutation Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2848-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DNAH3 Pathway Commons Protein-Protein Interactions 1.0 null neck TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.308974 MTDH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.19039 aplasia/hypoplasia involving bones of the hand HPO Gene-Disease Associations 1.0 null BRD-K35826866 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.2771 H3K4me3_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null abnormality of the plantar skin of foot HPO Gene-Disease Associations 1.0 null Peripheral nervous system neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.228 GSE84462,GSE84762_0_v_7_ezh2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Thyroid gland carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.683 strabismus HPO Gene-Disease Associations 1.0 null nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.523194 Wing disc TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.009 Lung adenocarcinoma_LUAD_TCGA-44-8119-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MEWO COSMIC Cell Line Gene Mutation Profiles 1.0 null PTPN21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95382 cerebral cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.061285 BRD-K30812092 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.31554 HT115 CCLE Cell Line Gene Mutation Profiles 1.0 null abnormality of the head HPO Gene-Disease Associations 1.0 null Myeloid neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.271 BRD-K36074653 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.85307 H3K23me2_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K64992851 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.53652 PMC6879454-Data_Sheet_1.xlsx-AA_in_vitro-Unnamed_4_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null Preosteoblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.963 sulfadimidine-3765 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Lung Diseases CTD Gene-Disease Associations 1.0 1.13007 Perturb_5140_KO_Rn7sk_ERP002405 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 5.71748 primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.19144 peripheral nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.247399 abnormality of the genital system HPO Gene-Disease Associations 1.0 null BRD-K52259096 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.42432 Exine COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.49 posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.01933 hair follicle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.683511 polydactyly DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.614356 NRL_Deficiency_GDS1693_237_mouse_Photoreceptors cells of retinas at P6 GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null abnormal lymph organ size MPO Gene-Phenotype Associations 1.0 null GTEX-XPVG-2826-SM-4B66J GTEx Tissue Sample Gene Expression Profiles 1.0 0.884914 abnormality of the ribs HPO Gene-Disease Associations 1.0 null Neural Tube Defects CTD Gene-Disease Associations 1.0 1.03752 CCKBR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.24132 EEF1A2 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Lip disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.517 Sebaceous gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.213 rt4 HPA Cell Line Gene Expression Profiles -1.0 -0.923654 BXPC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.14504 H3K4me3_fibroblast of skin of abdomen_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null layer VI of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.05237 GSE100316_5_v_2_mtor_mouse RummaGEO Gene Perturbation Signatures 1.0 null abnormal hemoglobin MPO Gene-Phenotype Associations 1.0 null ASTE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.46507 posterior (caudal) superior temporal cortex (area 22c)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.29977 ANKRD49 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.76499 EPLC-272H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.87782 Tonometry DisGeNET Gene-Phenotype Associations 1.0 null GSE60837_0_v_4_bcl9_mouse RummaGEO Gene Perturbation Signatures -1.0 null lung cancer GWASdb SNP-Disease Associations 1.0 0.739121 COLO 853 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.15782 RAD21 ENCODE Transcription Factor Targets 1.0 null PMC8567138-Table_2.xlsx-Sheet1-IGFBP5_AND_IGFBP7_NOT_IGFBP3_NR4A2 Rummagene Transcription Factor Associations 2026 1.0 null Urinary Bladder Neoplasms HuGE Navigator Gene-Phenotype Associations 1.0 null fh23 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.771 Sensory system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.163 GTEX-QMR6-1326-SM-32PLB GTEx Tissue Sample Gene Expression Profiles 1.0 0.847426 UACC-812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.960528 aplasia/hypoplasia of the thumb HPO Gene-Disease Associations 1.0 null GSE150072,GSE169209_4_v_10_qser1_human RummaGEO Gene Perturbation Signatures 1.0 null HEC1B CCLE Cell Line Gene Mutation Profiles 1.0 null VSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.9412 GTEX-XQ3S-0006-SM-4BOQ4 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.910306 UACC-893 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-T6MO-0003-SM-3NMAG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.10845 GTEX-QCQG-1426-SM-48U22 GTEx Tissue Sample Gene Expression Profiles 1.0 1.47962 RMSYM DepMap CRISPR Gene Dependency 1.0 2.87859 abnormality of metabolism/homeostasis HPO Gene-Disease Associations 1.0 null H3K9ac_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-QVUS-0006-SM-3GAE8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.972343 VIIB Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.928224 SRRM2 Pathway Commons Protein-Protein Interactions 1.0 null Motor Delay DisGeNET Gene-Phenotype Associations 1.0 null TBCD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.19305 NDUFB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75053 CTCF_WERI-Rb-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R55E-0426-SM-2TC65 GTEx Tissue Sample Gene Expression Profiles 1.0 1.72134 GTEX-WFG7-0826-SM-3GIKU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.890744 Neural tube TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.097 gallamine triethiodide-5735 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Tinea favosa DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.206 sensory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.045401 telencephalon TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.058264 EPLC272H DepMap CRISPR Gene Dependency 1.0 2.12763 increased neutrophil cell number MPO Gene-Phenotype Associations 1.0 null pontine reticular formation, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.864175 H3K4me3_cardiac mesoderm_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null abnormal leukocyte cell number MPO Gene-Phenotype Associations 1.0 null GTEX-NFK9-0006-SM-3GACS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.20295 TCOF1 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K88070373 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.4796 BRD-K38969544 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.67635 CALHM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.11888 neoplasm by anatomical site HPO Gene-Disease Associations 1.0 null inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.01534 tubocurarine chloride-5449 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null UBTF_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TC-71 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.38322 posteroventral (inferior) parietal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.55539 Ellis-Van Creveld syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.306 H3K9ac_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE102757_1_v_0_panobinostat_mouse RummaGEO Drug Perturbation Signatures 1.0 null MIR122_Antisense Inhibition_GDS1729_759_mouse_Livers (from C57BL/6 adult males) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Infundibulocystic basal cell carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.302 HEL9217 CCLE Cell Line Gene CNV Profiles 1.0 1.35472 RCM-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null OVCAR-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.838053 H3K4me2_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ventrolateral prefrontal cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.05203 SREBF1 ChEA Transcription Factor Targets 1.0 null GSE224763_1_v_0_rif1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE161295_0_v_1_cdk8_mouse RummaGEO Gene Perturbation Signatures 1.0 null ARL8B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26017 globus pallidus, internal segment, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.14656 Melanoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.603 Skin Tag DisGeNET Gene-Phenotype Associations 1.0 null GSE242199_6_v_7_ntrk2_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-WFG7-0001-SM-3P61S GTEx Tissue Sample Gene Expression Profiles -1.0 -1.32803 Hepm TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.557 GLI-SUFU complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.628 GSE199255,GSE199356_6_v_1_pds5a_mouse RummaGEO Gene Perturbation Signatures -1.0 null cardiac fibroma HPO Gene-Disease Associations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QZ-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RI1 DepMap CRISPR Gene Dependency 1.0 2.30826 organ development GO Biological Process Annotations 2015 1.0 null thyroid gland HPA Tissue Protein Expression Profiles 1.0 0.96344 H3K4me1_Penis Foreskin Fibroblast Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PMC12178829-mmc4.xlsx-Sheet_4-MEG3-KD_Up-ID_AR Rummagene Transcription Factor Associations 2026 1.0 null NFYA_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.43628 basal cell carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.41052 ZNF263 ENCODE Transcription Factor Targets 1.0 null G protein-coupled receptor binding GO Molecular Function Annotations 2023 1.0 null H3K4me3_cardiac mesoderm_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null Perturb_16933_OE_Hlx_SRP070641 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 14.6069 bed nucleus of stria terminalis, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.895996 FAM217B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48737 H3K4me3_MCF-7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null sulfachlorpyridazine-2191 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null NCI-H1838 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07691 STK38L Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_GM06990_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null PMC11266089-Table3.XLSX-Fig1_Disease_targets-TP53_TP53 Rummagene Transcription Factor Associations 2026 1.0 null Cell type cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.33 H3K4me3_K562_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null COG7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.53438 RPMI8402 CCLE Cell Line Gene CNV Profiles 1.0 1.59924 phenotypic variability HPO Gene-Disease Associations 1.0 null Foregut TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.291 primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.2694 Perturb_5009_Mut_Sall4_ERP122174 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.84763 H3K4me3_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC8185471-mmc4.xlsx-D4-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_4_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15 Rummagene Transcription Factor Associations 2026 1.0 null Mandible TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.525 Signaling by Hedgehog Reactome Pathways 2014 1.0 null MDA-MB-415 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.54965 KMS12BM CCLE Cell Line Gene CNV Profiles -1.0 -1.385 Bone marrow disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.255 paracentral lobule, posterior part, right, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -3.2787 H3K4me3_epithelial cell of proximal tubule_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null stratum basale TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.952116 SP in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.41212 YAPC CCLE Cell Line Gene Expression Profiles -1.0 -1.95583 GTEX-T5JW-0426-SM-4DM7M GTEx Tissue Sample Gene Expression Profiles 1.0 1.83711 GSE145915_0_v_2_pcm1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Neuronal ribonucleoprotein granule COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.696 dorsolateral prefrontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.58742 PHF21B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43599 neoplasm of the stomach HPO Gene-Disease Associations 1.0 null sclc21h HPA Cell Line Gene Expression Profiles 1.0 0.87134 Intestine TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 milia HPO Gene-Disease Associations 1.0 null 496100409_FWM_no dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.37152 Normoblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.52 EGR1_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null cell COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.303655 GTEX-WFON-0326-SM-3GIKX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.22585 Pancreatic cancer cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.38 GSE153137,GSE153140_2_v_0_mettl5_mouse RummaGEO Gene Perturbation Signatures -1.0 null CAL-85-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.68756 Integumentary system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.313 BRD-A71666580 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.34549 cleft palate HPO Gene-Disease Associations 1.0 null THRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 49.0989 KLF4-18358816-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null Perturb_6658_KO_Egfr_SRP188688 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.98717 BRD-K14364923 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.09626 GSE182680,GSE182683_0_v_4_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-NPJ8-0007-SM-2D7VX GTEx Tissue Sample Gene Expression Profiles -1.0 -3.23793 RBM10 Pathway Commons Protein-Protein Interactions 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YT-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GMFB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.36437 sertoli cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.393442 GTEX-OHPM-0006-SM-2HMKU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.87555 H3K9ac_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null abnormal hematopoietic system morphology/development MPO Gene-Phenotype Associations 1.0 null Hair TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.128 GTEX-XMK1-2026-SM-4B65K GTEx Tissue Sample Gene Expression Profiles 1.0 1.60944 Large cell medulloblastoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.513 Perturb_5103_KO_Ssrp1_SRP235595 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.65198 orbital frontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.978319 abnormality of limbs HPO Gene-Disease Associations 1.0 null Fetalbrain BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 2.2603 POLR2A_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null RPMI 8226 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.852229 Lung adenocarcinoma_LUAD_TCGA-MP-A4T6-01A-32R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE237040_4_v_1_notch3_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me1_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE200352_11_v_3_pparg_mouse RummaGEO Gene Perturbation Signatures -1.0 null Lung adenocarcinoma_LUAD_TCGA-86-A456-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4723-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 GSE162892_3_v_0_sox9_human RummaGEO Gene Perturbation Signatures 1.0 null ventrolateral prefrontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.09075 lomefloxacin-3620 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-P78B-2526-SM-3P5ZY GTEx Tissue Sample Gene Expression Profiles 1.0 0.916993 18787207-TableS2 GeneSigDB Published Gene Signatures 1.0 null DDX54 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.23978 fibrous tissue neoplasm HPO Gene-Disease Associations 1.0 null BRD-K56563758 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.27072 Ciliary basal body COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.703 Kidney Chromophobe_KICH_TCGA-KN-8437-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SHSY5Y DepMap CRISPR Gene Dependency 1.0 2.12847 ZNF669 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.2 CRCGN008_HEPG2_24H:O01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.09045 NCI-H1092 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11112 GTEX-XOT4-0326-SM-4B66S GTEx Tissue Sample Gene Expression Profiles 1.0 2.4521 TMEM14B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02411 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A7Q1-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null basal cell nevus syndrome OMIM Gene-Disease Associations 1.0 null HSPA1B Pathway Commons Protein-Protein Interactions 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TM-A84H-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null T24 BioGPS Cell Line Gene Expression Profiles 1.0 0.937978 BACH1 ENCODE Transcription Factor Targets 1.0 null heterogeneous HPO Gene-Disease Associations 1.0 null PPOX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65057 PMC11585558-41467_2024_54547_MOESM8_ESM.xlsx-TP53_vs_WT_DEG_FFPE-gene_name_TP53 Rummagene Transcription Factor Associations 2026 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20H-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE169571_0_v_2_dexamethasone_mouse RummaGEO Drug Perturbation Signatures 1.0 null Ovarian carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.085 SMIM20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05504 H3K4me2_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CMK115 DepMap CRISPR Gene Dependency 1.0 2.76989 UBTF ENCODE Transcription Factor Targets 1.0 null Lung adenocarcinoma_LUAD_TCGA-NJ-A4YP-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sarcoma_SARC_TCGA-DX-A6YV-01A-12R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Endometrioma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.913 pancreatic cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.333949 KURAMOCHI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.80813 GSE143994_2_v_1_ythdf1_human RummaGEO Gene Perturbation Signatures 1.0 null EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-POMQ-1426-SM-3P61D GTEx Tissue Sample Gene Expression Profiles 1.0 1.58419 KIAA0319L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.87175 COG8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9471 abnormality of the skeletal system HPO Gene-Disease Associations 1.0 null Immune system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.413 anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.94411 Perturb_13785_OE_IL10RB_SRP329434 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 7.5206 anemia MPO Gene-Phenotype Associations 1.0 null BRD-K32370845 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.14626 GSE145990_1_v_0_ibrutinib_human RummaGEO Drug Perturbation Signatures 1.0 null outer CP in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.47912 GTEX-T6MN-2726-SM-4DM77 GTEx Tissue Sample Gene Expression Profiles 1.0 1.08645 GSE198165,GSE198166_9_v_10_zfp266_mouse RummaGEO Gene Perturbation Signatures 1.0 null KHDRBS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.28399 motor nucleus of trigeminal nerve Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.16435 GSE125153_1_v_0_bcl3_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-Q2AI-0006-SM-2I3FG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.63248 KMS-21BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.16828 abnormal leukocyte morphology MPO Gene-Phenotype Associations 1.0 null regional abnormality of skin HPO Gene-Disease Associations 1.0 null ECC12 CCLE Cell Line Gene Expression Profiles -1.0 -2.12427 integumentary system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.13712 posterior (caudal) superior temporal cortex (area 22c)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.91436 primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.97329 Dysostosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.44 m9 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.026 NR1I2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.8848 H3K27ac_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70T-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE242290_3_v_11_glutathione_human RummaGEO Drug Perturbation Signatures -1.0 null Hepatobiliary disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.265 BRD-K55459289 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.33637 embryonic structure TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.06912 oral cleft HPO Gene-Disease Associations 1.0 null Peripheral nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.235 PUS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.70766 PAN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.60924 Heart BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.870672 Smooth endoplasmic reticulum membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.578 Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC4325629__F1 PFOCR Pathway Figure Associations 2024 1.0 null MHH-ES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08289 H3K9ac_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PMC6723230__F2 PFOCR Pathway Figure Associations 2023 1.0 null hsa-miR-548x TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 dorsal thalamus_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.6463 H3K4me2_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_BE2C_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H146 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22468 BRD-K28349636 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.18959 EZH2_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PLAG1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 95.6667 MHH-ES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.62857 H3K4me3_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null hippocampus (hippocampal formation)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.931343 GPCR ligand binding Reactome Pathways 2024 1.0 null Retinal cone TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.744 H3K4me3_Skeletal Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MGA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.2399 SARS-CoV MA15_Day4-PFU-10^4_None_GSE33266 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.15576 BRD-K48699175 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.11303 PPP6R1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24702 abnormal shape of the frontal region HPO Gene-Disease Associations 1.0 null LU-139 COSMIC Cell Line Gene Mutation Profiles 1.0 null CRCGN017_MCF10A.WT.HP_24H:A16 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.2864 GTEX-PWN1-2426-SM-48TDD GTEx Tissue Sample Gene Expression Profiles 1.0 1.33875 membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null enlarged urinary bladder MGI Mouse Phenotype Associations 2023 1.0 null hippocampus (hippocampal formation)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.06035 GTEX-S3XE-0006-SM-3K2AA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.41881 HEC265 CCLE Cell Line Gene Mutation Profiles 1.0 null abnormality of the male genitalia GWASdb SNP-Phenotype Associations 1.0 0.217115 NURR1 MotifMap Predicted Transcription Factor Targets 1.0 null BRD-K71842353 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.61368 GTEX-TKQ2-0004-SM-3NMAC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16872 adult TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.572018 amygdaloid complex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.949556 neural tube TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.62991 H3K4me3_WI38_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null TTC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.72059 NTERA-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.67234 BRD-K63102090 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.90846 BRD-K06994380 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.09933 PON2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.04144 Kidney Chromophobe_KICH_TCGA-KN-8426-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Muscular system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 MT-ND6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.44898 H3K4me1_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE147876,GSE147877_4_v_7_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null Transmembrane receptor, patched InterPro Predicted Protein Domain Annotations 1.0 null Basal cell carcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.203 GSE198165,GSE198166_5_v_10_zfp266_mouse RummaGEO Gene Perturbation Signatures -1.0 null Autoimmune disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.04 inner CP in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.989922 H3K9ac_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null negative regulation of response to stimulus GO Biological Process Annotations 2015 1.0 null immune system phenotype MPO Gene-Phenotype Associations 1.0 null CCNA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51545 Gastrula TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.055 iris coloboma HPO Gene-Disease Associations 1.0 null primary spermatocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.195945 ventrolateral prefrontal cortex_8 yrs_M_12981 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.951533 WDR77 Pathway Commons Protein-Protein Interactions 1.0 null NCIH2081 CCLE Cell Line Gene CNV Profiles 1.0 1.51308 Inherited metabolic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.108 basal cell carcinoma, somatic OMIM Gene-Disease Associations 1.0 null Cerebral Calcification DisGeNET Gene-Phenotype Associations 1.0 null CCNT2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ChIP_K27me3_17603471_mouseMEF ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null M band COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.569 GTEX-WFON-1726-SM-4LVMQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.854901 H3K4me3_fibroblast of lung_hg19_5 ENCODE Histone Modification Site Profiles 1.0 null Dorsal aorta TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.262 Disease Reactome Pathways 2014 1.0 null NCIH1395 CCLE Cell Line Gene Expression Profiles 1.0 2.21162 SRF_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Tumor Cell Invasion DisGeNET Gene-Phenotype Associations 1.0 null BRD-K36164005 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.29743 GTEX-RVPV-0008-SM-47JYW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13096 POLR2AphosphoS5_SK-N-MC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormal skin appearance MPO Gene-Phenotype Associations 1.0 null GTEX-R45C-0006-SM-3GAD6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.86091 GSE248858_6_v_3_tcpobop_mouse RummaGEO Drug Perturbation Signatures 1.0 null salivary gland HPA Tissue Protein Expression Profiles 1.0 0.96344 increased neutrophil cell number IMPC Knockout Mouse Phenotypes 1.0 null lateral ventricle HPA Tissue Protein Expression Profiles -1.0 -0.897918 Umbilical artery TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.566 BRD-K97255584 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.63381 MAPK8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.19544 H2AFZ_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null UMUC7 DepMap CRISPR Gene Dependency 1.0 2.63825 GSE126127_0_v_4_prmt1_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_133_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null abnormality of the abdomen HPO Gene-Disease Associations 1.0 null Pilomatrixoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.29 Familial meningioma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.47 midbrain reticular formation, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.87835 HINFP JASPAR Predicted Transcription Factor Targets 1.0 null calcification of falx cerebri HPO Gene-Disease Associations 1.0 null BRD-K93040255 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.1019 GTEX-WYBS-0326-SM-3NM8S GTEx Tissue Sample Gene Expression Profiles 1.0 0.898099 sirolimus_homo sapiens_gpl6244_gse15703 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null germ layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.1554 SW403 DepMap CRISPR Gene Dependency 1.0 3.41354 Tenocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.657 enamel organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.851686 Perturb_6137_KO_Yap1/Wwtr1_SRP314027 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -9.21068 GTEX-X4EO-0006-SM-3P5ZF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.885816 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2A1-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pigmented Basal Cell Carcinoma DisGeNET Gene-Disease Associations 1.0 null H3K4me3_cardiac mesoderm_hg19_8 ENCODE Histone Modification Site Profiles 1.0 null NCI-H1651 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22468 abnormal hematocrit MPO Gene-Phenotype Associations 1.0 null palmar pits HPO Gene-Disease Associations 1.0 null multicellular organismal process GO Biological Process Annotations 2015 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-8513-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE245134_2_v_3_atg5_mouse RummaGEO Gene Perturbation Signatures 1.0 null ALVA31 BioGPS Cell Line Gene Expression Profiles 1.0 1.02269 H3K4me3_cardiac muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null KYSE-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.80799 GSE87412,GSE92423_3_v_4_dnmt3a_mouse RummaGEO Gene Perturbation Signatures 1.0 null TUHR14TKB DepMap CRISPR Gene Dependency 1.0 3.86325 BRD-K14081852 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00047 RBBP5_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ ENCODE Transcription Factor Targets 1.0 null PMC7456018-12885_2020_7318_MOESM1_ESM.docx-0-PAX8_PAX8 Rummagene Transcription Factor Associations 2026 1.0 null zygote TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.072744 GSE122215,GSE122217_5_v_2_peg10_mouse RummaGEO Gene Perturbation Signatures -1.0 null PANC1005 CCLE Cell Line Gene CNV Profiles -1.0 -1.40652 aplasia/hypoplasia of the distal phalanx of the thumb HPO Gene-Disease Associations 1.0 null Auditory vesicle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.177 inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.0611 GTEX-S3XE-1526-SM-4AD5A GTEx Tissue Sample Gene Expression Profiles 1.0 0.922066 BRD-K15690866 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.15668 HPF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.34706 KDM4D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.04613 PPM1A Pathway Commons Protein-Protein Interactions 1.0 null BRD-K04087396 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.25956 Nr2e1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.7572 H3K4me3_fibroblast of lung_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null GTEX-OHPK-1726-SM-48TC4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.844927 eyelid TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.288514 lateral orbital frontal cortex (area 12/47) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.2892 VZ in posterosuperior (dorsal) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.948112 Prostate adenocarcinoma_PRAD_TCGA-KC-A7F5-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Glucose Intolerance CTD Gene-Disease Associations 1.0 1.11151 POLR2AphosphoS5_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LU99 CCLE Cell Line Gene Expression Profiles 1.0 1.68535 Msx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.7531 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A556-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ELF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_A549_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null limb TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.467273 nervous system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.057697 Cerebral hemisphere TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Apical bud TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.929 GTEX-POMQ-0006-SM-33HBY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.52465 KMRC3 CCLE Cell Line Gene CNV Profiles -1.0 -1.66196 PPIA Pathway Commons Protein-Protein Interactions 1.0 null GSE129725_1_v_5_bmal1_mouse RummaGEO Gene Perturbation Signatures 1.0 null USP7 Hub Proteins Protein-Protein Interactions 1.0 null aplasia/hypoplasia involving the metacarpal bones HPO Gene-Disease Associations 1.0 null EIF3I Pathway Commons Protein-Protein Interactions 1.0 null abnormality of head or neck HPO Gene-Disease Associations 1.0 null Coloboma Of Iris DisGeNET Gene-Disease Associations 1.0 null GSE141726,GSE141733_1_v_0_angiotensin ii_mouse RummaGEO Drug Perturbation Signatures -1.0 null Fatty Liver CTD Gene-Disease Associations 1.0 1.4294 GTEX-OHPN-2926-SM-3LK65 GTEx Tissue Sample Gene Expression Profiles 1.0 1.19373 BRD-K13567350 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.43186 hsa-miR-937 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 MOLM16 CCLE Cell Line Gene Mutation Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4889-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TMEM88B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.39504 regulation of smoothened signaling pathway GO Biological Process Annotations 2025 1.0 null KLF10 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 102.708 GGTLC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43776 aplasia/hypoplasia involving bones of the upper limbs HPO Gene-Disease Associations 1.0 null cartilage TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.058154 yohimbic acid-2147 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null H3K4me1_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SCARA5_Down Expression_GSE32323_611_human_Colorectal Cancer Cell lines GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null lower limb region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.1967 ML1 CCLE Cell Line Gene Expression Profiles -1.0 -1.77519 lens fiber TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.28213 ventrolateral prefrontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.40401 CD3EAP Pathway Commons Protein-Protein Interactions 1.0 null Female reproductive organ cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.555 HS888T CCLE Cell Line Gene Expression Profiles -1.0 -1.69072 Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z6-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Secondary enamel knot TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.147 H3K4me3_GM12865_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CLTC Pathway Commons Protein-Protein Interactions 1.0 null ALG10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.31881 BRD-K26272845 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.83914 KIF26A Pathway Commons Protein-Protein Interactions 1.0 null ZNF263 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.8148 Primary hematopoietic stem cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.04143 SNU-668 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.858562 Somite TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.958 19605494-TableS3 GeneSigDB Published Gene Signatures 1.0 null RSV-A2_24Hour-KO_RSV_None_GSE18170 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.00187 PITPNM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15107 PSMB6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.11661 intracellular organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.243879 GSE211126_3_v_4_hapln1_mouse RummaGEO Gene Perturbation Signatures -1.0 null PLA1A Pathway Commons Protein-Protein Interactions 1.0 null ventrolateral prefrontal cortex_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.04339 H3K4me3_HL-60_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hematopoietic system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056391 BRD-K23547378 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.23438 GTEX-QESD-0006-SM-2I5G6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04171 PMC9314667-Table_1.xlsx-Regulons-SOX10_SOX10 Rummagene Transcription Factor Associations 2026 1.0 null GSE235066_7_v_0_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null H3K27me3_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null VIIIA, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.729 Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YR-11A-13R-A10U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GYG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51791 GTEX-QEL4-0426-SM-3GACZ GTEx Tissue Sample Gene Expression Profiles 1.0 0.983086 MZ in posterodorsal (superior) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03215 MYL6 Pathway Commons Protein-Protein Interactions 1.0 null JUND_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Stratum basale TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.801 H3K4me3_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-PWOO-2326-SM-2S1PQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.909913 PMC11438719-43032_2024_1653_MOESM4_ESM.xlsx-dNKall6orig_fdr01-dNK_MAF_1_MAF Rummagene Transcription Factor Associations 2026 1.0 null BRD-K24997610 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.00444 H3K4me3_GM12866_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SK-MEL-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.906928 A-172 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.57 GTEX-RU72-2626-SM-4GIE1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.98306 GTEX-TKQ2-1526-SM-4DXUN GTEx Tissue Sample Gene Expression Profiles 1.0 1.56957 Nervous system benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.159 Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z2-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_30_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.59893 Fast muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.722 GTEX-S341-0008-SM-4AD6D GTEx Tissue Sample Gene Expression Profiles -1.0 -1.36534 Reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.74 CRCGN015_HEPG2_48H:H19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.31348 ME-180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.901347 BRD-K65392756 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.23022 CSL-Notch-Mastermind transcription factor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.708 H3K27me3_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null IRF2BP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44554 Vascular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.247 Cerebral cortex TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 QGP1 CCLE Cell Line Gene Mutation Profiles 1.0 null H3K4me3_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-R55F-0226-SM-48FCI GTEx Tissue Sample Gene Expression Profiles 1.0 0.975522 intracellular part LOCATE Curated Protein Localization Annotations 1.0 null Nfat5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 29.0 H3K4me1_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE186223,GSE186224_6_v_3_hmces_mouse RummaGEO Gene Perturbation Signatures 1.0 null CRCGN013_HEPG2_24H:H24 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.55815 YWHAG Pathway Commons Protein-Protein Interactions 1.0 null GTEX-U3ZN-0002-SM-3NMDF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.22802 primary auditory cortex (core)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.8449 SIN3A_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-15b TargetScan Predicted Conserved microRNA Targets 1.0 0.085563 VI, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.45429 H3K9ac_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null superior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.14184 H3K9ac_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-F6-A8O4-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC3737722__F7 PFOCR Pathway Figure Associations 2023 1.0 null thyroid carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.348246 GSE241701_4_v_0_daxx_mouse RummaGEO Gene Perturbation Signatures -1.0 null central nervous system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.055141 GTEX-U8T8-0005-SM-3DB8F GTEx Tissue Sample Gene Expression Profiles -1.0 -1.1524 PMC11659471-41398_2024_3203_MOESM2_ESM.xlsx-Table_SE_9-Table_SE9_Z_scores_comparing_signficant_genes_from_OUD_dataset_Seney_et_al_and_rat_models_of_heroin_and_or_LPS_injection_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null NFYB ENCODE Transcription Factor Targets 1.0 null primary auditory cortex (core)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.0781 Exocrine gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 IGF1R CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.29959 BRD-K35209334 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.01206 HCC1493 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.843033 tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.0282 SNU840 DepMap CRISPR Gene Dependency 1.0 2.39003 HCC827 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.39309 GTEX-S95S-0005-SM-2XCEC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.20242 abnormality of upper lip HPO Gene-Disease Associations 1.0 null GSE130690,GSE130692_2_v_0_sirt6_mouse RummaGEO Gene Perturbation Signatures -1.0 null Intestinal cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.581 BRD-K85697068 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.24612 LAMTOR5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.29959 PNU-0230031-4288 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-VJYA-1726-SM-3NMDQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.81282 A-427 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.62521 DMS 454 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.17396 outer dental epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.762811 skin stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.405935 inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12981 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.30552 H3K4me1_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XQ3S-0001-SM-4B64K GTEx Tissue Sample Gene Expression Profiles -1.0 -0.998489 SW48 COSMIC Cell Line Gene Mutation Profiles 1.0 null abnormality of phalanx of finger HPO Gene-Disease Associations 1.0 null SWSAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.87919 papillary thyroid carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.609666 Eggshell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.745 MFE280 CCLE Cell Line Gene Mutation Profiles 1.0 null KIF3A Pathway Commons Protein-Protein Interactions 1.0 null EP300_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R55D-0006-SM-3GIJS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.900514 Mesoderm TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.133 albendazole-oxide LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.25584 vinpocetine-7213 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Ectodermal dysplasia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.149 Sexine COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.728 primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.854181 GSE198982,GSE198986_1_v_2_daunorubicin_human RummaGEO Drug Perturbation Signatures 1.0 null Thap11 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.6848 gastrointestinal system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.042951 RECQL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.39476 H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null female reproductive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.454512 SOHLH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.23855 SP in rostral perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.46381 Hoxc13_OE_GDS1890_174_mouse_Skin GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null monogenic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.81059 Short Distal Phalanx DisGeNET Gene-Phenotype Associations 1.0 null NOP10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15218 H3K27ac_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Fibrosis CTD Gene-Disease Associations 1.0 1.07447 Jaw Neoplasms HuGE Navigator Gene-Phenotype Associations 1.0 null GSE169571_3_v_4_dexamethasone_mouse RummaGEO Drug Perturbation Signatures -1.0 null loss GeneRIF Biological Term Annotations 1.0 null mRNA_ESX1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null GTEX-S341-0006-SM-3NM8D GTEx Tissue Sample Gene Expression Profiles -1.0 -2.22467 H3K4me3_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WY7C-2626-SM-3NB2P GTEx Tissue Sample Gene Expression Profiles 1.0 0.912861 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A6W2-01A-21R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE205070_1_v_7_mertk_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC9352753__F3 PFOCR Pathway Figure Associations 2024 1.0 null H3K4me2_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null JHUEM1 DepMap CRISPR Gene Dependency 1.0 3.34528 BRD-K86966177 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.0388 Nfatc1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 27.3072 GTEX-SJXC-0326-SM-2XCFI GTEx Tissue Sample Gene Expression Profiles 1.0 2.11184 Cerebellar granule cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.176 BRD-K90934902 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.27811 HOXD13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.06199 H3K4me3_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null endometrium HPA Tissue Gene Expression Profiles 1.0 0.896682 H3K4me3_HEK293_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GT-06A-12R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XUW1-0626-SM-4BOP4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.06897 GSE149442_1_v_0_gdpd3_mouse RummaGEO Gene Perturbation Signatures -1.0 null skin TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.60249 SNU489 CCLE Cell Line Gene Expression Profiles -1.0 -1.4518 MZ7-MEL COSMIC Cell Line Gene Mutation Profiles 1.0 null BHT101 CCLE Cell Line Gene Expression Profiles -1.0 -1.54351 ATM_knockout_16_GDS1544 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -2.87354 GSE182680,GSE182683_5_v_9_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null chr1_44952751_A_C_b38 GTEx eQTL 2025 1.0 1.07192 SAP30_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormal immune system cell morphology MPO Gene-Phenotype Associations 1.0 null Enamel epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.797 TRIM28 ENCODE Transcription Factor Targets 1.0 null H3K9ac_Stomach Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null DOK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.30363 hsa-miR-3183 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 ERF::FIGLA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.8065 SNUC2A CCLE Cell Line Gene Mutation Profiles 1.0 null GTEX-PW2O-0006-SM-2I3DV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04077 hindlimb TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.081193 GSE198165,GSE198166_6_v_2_zfp266_mouse RummaGEO Gene Perturbation Signatures -1.0 null KHM-1B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.948114 L-428 COSMIC Cell Line Gene Mutation Profiles 1.0 null NALM16 DepMap CRISPR Gene Dependency 1.0 4.61646 Hydrocephalus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.17 Branchial arch TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.291 H3K27me3_CD14-positive monocyte_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TM31 CCLE Cell Line Gene Expression Profiles -1.0 -1.91179 GSE149123,GSE149128_3_v_0_cdk7_mouse RummaGEO Gene Perturbation Signatures -1.0 null SNU81 CCLE Cell Line Gene Expression Profiles -1.0 -1.49782 TAF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.59862 GTEX-O5YT-0007-SM-32PK7 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.5953 Bladder disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.135 D341MED CCLE Cell Line Gene Expression Profiles 1.0 2.17415 IZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.828137 PMC4029299__F3 PFOCR Pathway Figure Associations 2023 1.0 null mRNA_NRIP1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null PBX3_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K51572611 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.07349 GTEX-XYKS-0005-SM-4BRUD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.837172 H3K4me1_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null plasma membrane LOCATE Curated Protein Localization Annotations 1.0 null BRD-A69196860 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.10808 Lung adenocarcinoma_LUAD_TCGA-MN-A4N5-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bone cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.19 DPY30 Pathway Commons Protein-Protein Interactions 1.0 null YAPC GDSC Cell Line Gene Expression Profiles -1.0 -1.64897 MZ in posteror frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.2337 GTEX-WVLH-2926-SM-3MJG5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.851299 Cleft palate DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.376 BRD-K81110981 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.11173 DU145 CCLE Cell Line Gene CNV Profiles -1.0 -3.21049 skeletal muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055721 outer CP in rostral perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.21255 GTEX-SNOS-0006-SM-32PLH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.82153 Amacrine cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.965 erg_19359602_huvec_lof_human_gpl570_gds3557 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.520517 CORL105 CCLE Cell Line Gene CNV Profiles -1.0 -1.51952 Tapetum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.755 abnormality of the thumb HPO Gene-Disease Associations 1.0 null MPRIP Pathway Commons Protein-Protein Interactions 1.0 null H2AFX Pathway Commons Protein-Protein Interactions 1.0 null Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DI-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UBTD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87953 RCOR3-21632747-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null SNUC4 CCLE Cell Line Gene Mutation Profiles 1.0 null lateral group of nuclei, left, dorsal division Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.15472 ZBTB18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.2235 GSE226452_1_v_2_imiquimod_mouse RummaGEO Drug Perturbation Signatures -1.0 null ZSCAN4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.2159 GTEX-P4PQ-0008-SM-48TDX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.886296 EKVX Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.17396 HDLBP Pathway Commons Protein-Protein Interactions 1.0 null BRD-K69671285 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.22305 abnormality of the scapula HPO Gene-Disease Associations 1.0 null GSE214596,GSE214598_1_v_4_rosiglitazone_mouse RummaGEO Drug Perturbation Signatures -1.0 null abnormality of the rib cage HPO Gene-Disease Associations 1.0 null mc2 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.883 Signaling by Hedgehog Reactome Pathways 2024 1.0 null t60-adrenal_female_8w MoTrPAC Rat Endurance Exercise Training 1.0 1.85528 BRD-K35098144 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.04641 BRD-K46994278 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.31813 PU.1-20176806-MACROPHAGES-MOUSE ChEA Transcription Factor Targets 2022 1.0 null UBTF_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null lovastatin-2494 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null MAX_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC6473842__F2 PFOCR Pathway Figure Associations 2023 1.0 null H3K4me3_fibroblast of pedal digit skin_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null MYC_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WY7C-0526-SM-3NB3D GTEx Tissue Sample Gene Expression Profiles -1.0 -0.844042 Developmental disorder of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.223 SNU245 CCLE Cell Line Gene CNV Profiles -1.0 -1.39726 abnormality of the lip HPO Gene-Disease Associations 1.0 null GSE162892_4_v_0_sox9_human RummaGEO Gene Perturbation Signatures 1.0 null Salivary_Gland-myoepithelial cell Tabula Sapiens Gene-Cell Associations 1.0 -0.0858648 CAPAN-2 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.648 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A6HN-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC7849364-supp_gad.342378.120_Supplemental_Table_S4_.xlsx-Hoja1-Table_S4-_SIX2-associated_genes_identified_by_CUT_RUN_overlapping_with_differential_expression_by_SIX2_knockdown_SIX2 Rummagene Transcription Factor Associations 2026 1.0 null heart valve disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.117224 CALD1 Pathway Commons Protein-Protein Interactions 1.0 null POLR2A_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null A3/KAW Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.982927 Fin TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.414 hypotrichosis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.418768 H3K4me2_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.322 H3K4me3_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Mismatch repair cancer syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.014 Autosomal genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.951 GSE248858_4_v_2_tcpobop_mouse RummaGEO Drug Perturbation Signatures 1.0 null SOD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.57447 epidermis development GO Biological Process Annotations 2015 1.0 null HERC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52187 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3376-01A-02R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior (caudal) superior temporal cortex (area 22c)_11 yrs_F_12289 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.3296 A549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07599 TAF1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K44368508 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.0914 Muscle cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.944 Enamel organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.704 hematopoietic cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.065783 ZR-75-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.60033 thigh TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.120952 Stratum intermedium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.54 GSE85995_1_v_0_gata3_human RummaGEO Gene Perturbation Signatures 1.0 null GTF2F1 ENCODE Transcription Factor Targets 1.0 null Esophageal cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.032 anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.835371 GTEX-OXRL-0005-SM-3LK6A GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02954 H3K4me3_cardiac muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4989-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K57517066 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.88216 BRD-K62707745 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07266 PMC8437976-41416_2021_1470_MOESM2_ESM.xls-List_of_MAF_in_SNP_Rectum-Hugo_Symbol_MAF Rummagene Transcription Factor Associations 2026 1.0 null Crus I, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.30459 CTB-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null ovary HPA Tissue Gene Expression Profiles 1.0 1.23221 PMC11438719-43032_2024_1653_MOESM4_ESM.xlsx-dNKall6orig-dNK_MAF_1_MAF Rummagene Transcription Factor Associations 2026 1.0 null VAMP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43037 GSE81193_3_v_4_irf3_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-SNOS-1126-SM-4DM67 GTEx Tissue Sample Gene Expression Profiles 1.0 1.42824 forebrain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055638 CV-1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.685 Axoneme COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.46 Uterine epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.154 abnormality of the 4th metacarpal HPO Gene-Disease Associations 1.0 null atractyloside LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.03275 Hair follicle outer root sheath TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.624 Protein kinase CK2 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.339 dorsal cochlear nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.75945 Perturb_4365_KO_UTX/JMJD3_SRP158713 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A3JJ-11A-12R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE223609,GSE223610_0_v_1_kdm6a_human RummaGEO Gene Perturbation Signatures 1.0 null CFAP119 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.55415 H3K4me3_cardiac mesoderm_hg19_7 ENCODE Histone Modification Site Profiles 1.0 null EP300_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5088-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null endometrium_4b HPA Tissue Sample Gene Expression Profiles 1.0 0.841035 Follicular adenoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.513 POLR2E Pathway Commons Protein-Protein Interactions 1.0 null TP53INP2_OE_GDS5054_385_mouse_Muscle GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null enlarged spleen MGI Mouse Phenotype Associations 2023 1.0 null H3K4me3_keratinocyte_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null PMC5999604__F3 PFOCR Pathway Figure Associations 2024 1.0 null SALL4-18804426_ESC-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null CHD7_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A410-01A-11R-A32Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WK11-0926-SM-3NMAU GTEx Tissue Sample Gene Expression Profiles 1.0 1.09438 H3K27me3_cardiac mesoderm_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null NR2F2 ENCODE Transcription Factor Targets 1.0 null GTEX-P4QR-0008-SM-48TE2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.971947 G-402 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.40411 GSE225141,GSE225143_0_v_1_mettl3_mouse RummaGEO Gene Perturbation Signatures -1.0 null Neurula TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.019 hematopoietic stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.389289 inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.1394 GSE211126_3_v_0_hapln1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-UPJH-0626-SM-4IHJN GTEx Tissue Sample Gene Expression Profiles 1.0 1.06331 skin pit HPO Gene-Disease Associations 1.0 null hsa-miR-15a TargetScan Predicted Conserved microRNA Targets 1.0 0.088999 inner SZ in dorsomedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.08917 HNRNPA3 Pathway Commons Protein-Protein Interactions 1.0 null pancreas_6a HPA Tissue Sample Gene Expression Profiles -1.0 -1.48764 GTEX-N7MS-0011-R11A-SM-2HMJS GTEx Tissue Sample Gene Expression Profiles 1.0 0.876227 Glaucoma DisGeNET Gene-Disease Associations 1.0 null H3K4me3_Duodenum Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null OVCA 429 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.81133 Lymphoid leukemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.135 RKO COSMIC Cell Line Gene Mutation Profiles 1.0 null cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null Multiple endocrine neoplasia type 2B DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.335 SW620 BioGPS Cell Line Gene Expression Profiles -1.0 -0.867948 MXI1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MXI1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PL45 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.13197 supporting cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.35557 cerebral hemisphere TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.059508 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5VV-06A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LY2 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.838517 GSE248858_6_v_0_tcpobop_mouse RummaGEO Drug Perturbation Signatures 1.0 null GTEX-U3ZH-1526-SM-4DXV1 GTEx Tissue Sample Gene Expression Profiles 1.0 2.1445 SW684 GDSC Cell Line Gene Expression Profiles -1.0 -1.9184 GTEX-QLQ7-1826-SM-2S1R5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.955715 Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3Z7-01A-12R-A23N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XUJ4-0004-SM-4BOQE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.98719 Spiradenoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.138 H3K27me3_kidney_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Megacolon DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.368 X-linked monogenic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.532 GTEX-T5JC-0005-SM-4DM7B GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02146 GTEX-XPT6-0006-SM-4B66Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.46578 animal cap TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.360409 embryo TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.10579 19192944-table2 GeneSigDB Published Gene Signatures 1.0 null SF3B6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32694 ZNF878 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.24197 H3K4me3_MCF-7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-X5EB-2526-SM-4E3HY GTEx Tissue Sample Gene Expression Profiles 1.0 1.05691 H3K4me3_cardiac fibroblast_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null cardiac rhabdomyoma HPO Gene-Disease Associations 1.0 null BRD-K48147099 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.52746 GTEX-X638-0226-SM-47JZ9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.30061 primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.887392 Elaioplast COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.596 central nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.419242 H3K9ac_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null YARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.18566 halofantrine-6509 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GSE120413,GSE120447_4_v_2_bap1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Intraciliary transport particle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.123 H3K4me3_fibroblast of lung_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null THBS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80969 SNU175 CCLE Cell Line Gene Mutation Profiles 1.0 null PMC8988201-EMMM-14-e14990-s008.xlsx-Sheet1-Dataset_EV6_Wnt_and_Hh_pathway_associated_genes_assessed_for_differential_expression_after_GPR56_KD_AR Rummagene Transcription Factor Associations 2026 1.0 null organ system cancer GWASdb SNP-Disease Associations 1.0 0.126016 ureteric bud TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.266069 GTEX-U3ZH-0002-SM-3NMDD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.990536 subgenual (subcallosal) division of MFC (area 25) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.51422 BRD-K59221664 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.50993 Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null GSE125219,GSE125221_4_v_0_arid1a_human RummaGEO Gene Perturbation Signatures -1.0 null MKS complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.946 Autosomal recessive disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.55 GSE190534,GSE190536_0_v_3_cyclophosphamide_mouse RummaGEO Drug Perturbation Signatures -1.0 null KK-47 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.621 KLF15_KO_GDS4780_419_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GSE183327,GSE183328_1_v_0_ddit3_human RummaGEO Gene Perturbation Signatures 1.0 null lytic vacuole LOCATE Predicted Protein Localization Annotations 1.0 null Nevoid basal cell carcinoma syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 3.248 KYSE270 CCLE Cell Line Gene CNV Profiles 1.0 1.37924 MAZ_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Penis Foreskin Keratinocyte Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PK59 CCLE Cell Line Gene Mutation Profiles 1.0 null GTEX-XOTO-0226-SM-4B66H GTEx Tissue Sample Gene Expression Profiles 1.0 1.48555 GSE156708_1_v_2_fbxo11_human RummaGEO Gene Perturbation Signatures 1.0 null Congenital hypoplastic anemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.016 coloboma HPO Gene-Disease Associations 1.0 null TUBA3C Pathway Commons Protein-Protein Interactions 1.0 null Macrostomia CTD Gene-Disease Associations 1.0 2.88009 GTEX-WH7G-1926-SM-4LVMM GTEx Tissue Sample Gene Expression Profiles 1.0 1.2778 ovary_6b HPA Tissue Sample Gene Expression Profiles 1.0 1.1331 BRD-A14878925 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.46691 GSE242199_9_v_3_ntrk2_human RummaGEO Gene Perturbation Signatures -1.0 null VMRC-LCD Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.06345 GSE184210_0_v_1_glucagon_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE81193_3_v_2_irf3_mouse RummaGEO Gene Perturbation Signatures -1.0 null Respiratory system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.622 Kidney cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.27 Lymphoma_burkitts(Daudi) BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.863189 tetralogy of fallot DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.374809 DMS153 CCLE Cell Line Gene CNV Profiles 1.0 1.5587 PMC8833361__F8 PFOCR Pathway Figure Associations 2024 1.0 null amygdaloid complex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.04369 STAT4 MotifMap Predicted Transcription Factor Targets 1.0 null GTEX-QEG4-1126-SM-2S1P7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.76879 primary auditory cortex (core)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.76892 inhibitory GeneRIF Biological Term Annotations 1.0 null GSE196699_0_v_1_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CEBPB_CEBPB Rummagene Transcription Factor Associations 2026 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.11853 Perturb_15709_KD_Ctcf_SRP173291 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -7.62861 basal cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.02294 animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.03434 HIST1H2AI Pathway Commons Protein-Protein Interactions 1.0 null Skin - Sun Exposed (Lower leg) GTEx Tissue Gene Expression Profiles 2023 -1.0 -0.636835 hippocampus (hippocampal formation)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.843572 H3K4me3_brain microvascular endothelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null abnormality of the skin HPO Gene-Disease Associations 1.0 null GSE164087_0_v_1_jmjd8_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-X261-0011-R11A-SM-4E3JY GTEx Tissue Sample Gene Expression Profiles 1.0 0.909247 nalbuphine-2225 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null KDM5B ENCODE Transcription Factor Targets 1.0 null SNU-C2B COSMIC Cell Line Gene Mutation Profiles 1.0 null negative regulation of cell communication GO Biological Process Annotations 2015 1.0 null abnormality of the musculature HPO Gene-Disease Associations 1.0 null GSE232631_4_v_1_brca2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-X638-0426-SM-47JY2 GTEx Tissue Sample Gene Expression Profiles 1.0 3.06914 HCC12 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.922585 BRD-K44307624 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.31743 CCDC9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.48782 PKM Pathway Commons Protein-Protein Interactions 1.0 null GTEX-XGQ4-2026-SM-4AT6G GTEx Tissue Sample Gene Expression Profiles 1.0 1.25486 SK-N-FI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.995172 GTEX-VJYA-1426-SM-4KL1Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.91505 Bladder Urothelial Carcinoma_BLCA_TCGA-R3-A69X-01A-22R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EBNA1-20929547-CHIP-SEQ-RAJI-CELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Chromophil adenoma of the kidney DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.42 lateral mammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.92972 Intestinal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.659 Small intestine TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 RBBP5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null negative regulation of signaling GO Biological Process Annotations 2015 1.0 null BRD-K48478472 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.6375 TBL1XR1 ENCODE Transcription Factor Targets 1.0 null NFIC_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Neuroma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.112 abnormal form of the vertebral bodies HPO Gene-Disease Associations 1.0 null YAPC Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.51264 Purkinje layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.013 Dlx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.5275 Breast papillary carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.024 COLO792 CCLE Cell Line Gene Expression Profiles 1.0 1.59667 PPM1B Pathway Commons Protein-Protein Interactions 1.0 null MYC ENCODE Transcription Factor Targets 1.0 null BCLAF1 Pathway Commons Protein-Protein Interactions 1.0 null GRB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.77852 BRD-K35101110 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.20109 EP300_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K95369587 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.36946 CCDC87 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10031 Microspore TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.443 H3K4me3_H7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null LN428 CCLE Cell Line Gene Expression Profiles 1.0 1.53061 BRD-K50710722 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.92187 EP300_ES-Bruce4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SNOS-0008-SM-4DM6I GTEx Tissue Sample Gene Expression Profiles -1.0 -0.964504 ALPK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.75942 G3BP1 Pathway Commons Protein-Protein Interactions 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DH-A7UV-01A-12R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_astrocyte of the spinal cord_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CRCGN014_HEPG2_3H:N04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.1736 SREBP1-19666523-LIVER-MOUSE ChEA Transcription Factor Targets 2022 1.0 null USP42 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01425 KP-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null abnormality of the face HPO Gene-Disease Associations 1.0 null short phalanx of the thumb HPO Gene-Disease Associations 1.0 null GTEX-WRHU-1126-SM-4E3I1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.832506 GSE248858_5_v_3_tcpobop_mouse RummaGEO Drug Perturbation Signatures 1.0 null alpha-estradiol-2670 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K66526269 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.06388 496100554_FWM_no dementia_no TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.15341 PMC7773934-Table_1.XLSX-Table_S2-Supplementary_Table_2_TBX22_co-expressed_genes_detailed_results_TBX22 Rummagene Transcription Factor Associations 2026 1.0 null Pericardial mesothelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.676 GSE114883_1_v_5_romidepsin_human RummaGEO Drug Perturbation Signatures 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-A5NL-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K69536411 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.11047 HDAC2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDA-MB-468 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.2965 RGS3 Pathway Commons Protein-Protein Interactions 1.0 null ATPSCKMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.91256 male reproductive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.597666 BRD-K93127164 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.20774 PCLAF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.75791 ZBTB7A_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormality of finger HPO Gene-Disease Associations 1.0 null BCL3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEx Heart 20-29 vs 50-59 GTEx Tissue-Specific Aging Signatures 1.0 3.4187 Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20N-11A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_6573_KO_Gls/Mpc2_SRP338093 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.58949 HUES64_Cell_Line Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 1.21481 GTEX-Q734-0826-SM-48U1G GTEx Tissue Sample Gene Expression Profiles 1.0 0.840699 POLR2AphosphoS2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE145476_2_v_0_hopx_mouse RummaGEO Gene Perturbation Signatures 1.0 null wagenmann-froboese syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.677105 Ciliary pocket COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.808 GSE173810_0_v_3_igf2_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC4325629__F1 PFOCR Pathway Figure Associations 2023 1.0 null BRD-K93990956 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.21394 physical disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.63907 INTS14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.47597 caudal subdivision of medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.20827 GTEX-WFG7-0005-SM-3GIKM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.18758 Plantar Pits DisGeNET Gene-Phenotype Associations 1.0 null Primary B cells from cord blood Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 0.959182 DNM1 Pathway Commons Protein-Protein Interactions 1.0 null CHMP7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.63713 Signal Transduction Reactome Pathways 2014 1.0 null GSE196699_7_v_5_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null abnormality of the palate HPO Gene-Disease Associations 1.0 null POLR2AphosphoS2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null IX Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.8265 YWHAB Pathway Commons Protein-Protein Interactions 1.0 null Perturb_13048_KO_Il33_SRP259135 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.26924 dentate nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.90163 Gastrointestinal tract TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 biological regulation GO Biological Process Annotations 2015 1.0 null hsa-miR-3664-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 CAPN6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.60744 GTEX-S7SF-1326-SM-4AD4P GTEx Tissue Sample Gene Expression Profiles 1.0 1.27456 cell part LOCATE Predicted Protein Localization Annotations 1.0 null CLIC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.15534 PMC4920139__F1 PFOCR Pathway Figure Associations 2023 1.0 null NCI-H1048 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-NL4W-0006-SM-2I3GH GTEx Tissue Sample Gene Expression Profiles -1.0 -2.35932 dentate gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.59267 STAT1_01_21 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 0.91 VI, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.54095 ChIP_DMAP1_20946988 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null SALL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.55568 BRD-K97485956 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.32518 ABI2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85658 underlies GeneRIF Biological Term Annotations 1.0 null VIIIB Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.921346 BRD-K10849007 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.80874 BRD-K06743908 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.17609 cell part LOCATE Curated Protein Localization Annotations 1.0 null HADHA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.67398 H3K4me3_fibroblast of pedal digit skin_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Adult Medulloblastoma DisGeNET Gene-Disease Associations 1.0 null 496100346_FWM_no dementia_TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.05108 Endocrine organ benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.301 dorsolateral prefrontal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.00052 GTEX-T6MN-0005-SM-32PLJ GTEx Tissue Sample Gene Expression Profiles -1.0 -2.11393 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3426-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Integumentary system benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.22 vertebral fusion HPO Gene-Disease Associations 1.0 null BRD-K02707544 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.22736 amygdaloid complex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.905128 Ciliary plasm COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.459 GTEX-OIZH-2126-SM-3NB1P GTEx Tissue Sample Gene Expression Profiles 1.0 1.17072 GTEX-T8EM-0006-SM-3DB71 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.23551 PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_203_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null Perturb_17493_KO_Gpr115_SRP275685 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.78199 LYPD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.32806 CKAP4 Pathway Commons Protein-Protein Interactions 1.0 null CACNB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.06682 PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4 Rummagene Transcription Factor Associations 2026 1.0 null Distal tip TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.475 MDA-MB-134-VI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.840657 IX, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.993275 NCI-H196 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.868651 Disease of metabolism DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.266 GTEX-T5JW-0003-SM-3NMAD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.17522 NCI-H1792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.6129 GTEX-V955-0726-SM-3GAFG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.841136 outer CP in midinferior temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.01388 GTEX-WHSE-0926-SM-3NMBS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.92384 KRIT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.06462 neuroblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056543 GTEX-V955-0004-SM-3NMDH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.05595 GTEX-NL4W-0011-R11A-SM-2I3DW GTEx Tissue Sample Gene Expression Profiles 1.0 0.898419 Salivary_Gland-t cell Tabula Sapiens Gene-Cell Associations 1.0 -0.0479192 GTEX-UJMC-0005-SM-3GACU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.935067 intracellular COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.277038 epidermal cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.737206 regulation of cellular component organization GO Biological Process Annotations 2023 1.0 null H3K4me1_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MAZ ENCODE Transcription Factor Targets 1.0 null GSE79291_1_v_2_streptozotocin_mouse RummaGEO Drug Perturbation Signatures -1.0 null Microphthalmia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.361 Colorectal cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.566 anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.910555 H3K9me3_erythroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null abnormal hair growth MPO Gene-Phenotype Associations 1.0 null H3K27ac_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MGMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.31755 Lung adenocarcinoma_LUAD_TCGA-55-6986-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cyst TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.335 semen TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.19164 placenta_6b HPA Tissue Sample Gene Expression Profiles -1.0 -1.75184 GTEX-WHPG-0004-SM-3NMDO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.15491 Lung adenocarcinoma_LUAD_TCGA-75-7025-01A-12R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Mesonephric duct TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.666 Dorsal lip TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.908 abnormality of the nose HPO Gene-Disease Associations 1.0 null Neuroepithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.288 HSC4 CCLE Cell Line Gene Expression Profiles -1.0 -2.24508 CAL-33 GDSC Cell Line Gene Expression Profiles 1.0 1.54836 ARHGAP32 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_7828_OE_ALYREF_SRP111407 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.1675 Large intestine cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.57 496100608_FWM_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.0914 primary auditory cortex (core)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.59802 Endochondral bone TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.396 rostral ventral respiratory cell group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.10438 dermal hyperplasia MPO Gene-Phenotype Associations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RV-02A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TBX20 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.9673 Epidermal stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.194 regulation of cell communication GO Biological Process Annotations 2015 1.0 null PGR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26372 HEC151 CCLE Cell Line Gene Mutation Profiles 1.0 null BRD-K69423881 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.67163 alopecia MPO Gene-Phenotype Associations 1.0 null Perturb_16510_OE_Tafazzin_SRP284254 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 ARH-77 COSMIC Cell Line Gene Mutation Profiles 1.0 null FOSL2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Adult Kidney Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Nephritis CTD Gene-Disease Associations 1.0 1.0189 H3K4me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null BRD-K55916310 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.68994 Hypogonadotropic Hypogonadism DisGeNET Gene-Disease Associations 1.0 null Odontogenic Cysts HuGE Navigator Gene-Phenotype Associations 1.0 null TK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.20544 primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.33186 Acquired Kyphoscoliosis DisGeNET Gene-Disease Associations 1.0 null GSE161295_0_v_5_cdk8_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me1_lung_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K49103797 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.33182 CTCF-18555785-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null Alopecia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.76 H3K4me3_Caco-2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SOX2 ChEA Transcription Factor Targets 1.0 null endocrine gland cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.55518 Perturb_5565_KO_Tal1_SRP119777 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 7.23335 H3K4me3_choroid plexus epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SERPING1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.20142 GSE150349_0_v_1_msx1_mouse RummaGEO Gene Perturbation Signatures -1.0 null integral component of membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.256561 H3K4me3_GM12865_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null neoplasm GWASdb SNP-Phenotype Associations 1.0 0.10928 posteroventral (inferior) parietal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.10781 PMC6744561-41467_2019_12125_MOESM7_ESM.xlsx-Normal_309_TCF7_rep1_sorted_pea-Gene_Name_TCF7 Rummagene Transcription Factor Associations 2026 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5010-01A-02R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAFK JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.4515 GTEX-P44H-0006-SM-2XCFB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.856426 Acrocapitofemoral dysplasia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.27 GJB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.09982 Acute Myeloid Leukemia_LAML_TCGA-AB-2810-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EGR3_01_34 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.58695 GSE163920_1_v_0_sirt1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Type III polyketide synthase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.809 lung HPA Tissue Protein Expression Profiles -1.0 -0.897918 spermatocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.550503 layer V of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.07894 IMR32 CCLE Cell Line Gene CNV Profiles -1.0 -2.38254 BRD-K72561299 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.73372 Tongue epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.728 GSE111035,GSE111040_10_v_9_plag1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE158815_5_v_3_trib1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE205070_1_v_4_mertk_mouse RummaGEO Gene Perturbation Signatures 1.0 null CTCF_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null posteroventral (inferior) parietal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.85282 HCC2998 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_Fetal Brain Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SCLC-21H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.86917 BRD-K33912919 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00488 TGBC24TKB GDSC Cell Line Gene Expression Profiles 1.0 2.14297 Microphthalmos DisGeNET Gene-Disease Associations 1.0 null organ system benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.048802 H3K4me3_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null HUO-3N1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Secondary spermatocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.626 SHMT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.15462 POLR1C Pathway Commons Protein-Protein Interactions 1.0 null POMP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43479 hippocampus (hippocampal formation)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.03129 Cell projection membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.503 BRD-K45717258 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.61896 Thyroid cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.856 Male reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.499 H2AFZ_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null resulting GeneRIF Biological Term Annotations 1.0 null Esophagus - Muscularis GTEx Tissue Gene Expression Profiles 2023 1.0 2.94317 Perturb_12502_KD_SRGAP1_SRP389741 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 13.1378 Thoracic spine TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.664 superior temporal gyrus, right, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.52343 membrane part GO Cellular Component Annotations 2015 1.0 null Congenital nervous system abnormality DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.741 PSMC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61534 KDM4A ENCODE Transcription Factor Targets 1.0 null smooth muscle cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.165435 abnormal appendicular skeleton morphology HPO Gene-Disease Associations 1.0 null amygdaloid complex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.855616 H3K4me3_HEK293_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null BRD-K23432132 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.50327 FASN Pathway Commons Protein-Protein Interactions 1.0 null Perturb_14505_KO_Tgfb3_SRP020224 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 8.69645 GTEX-S4Q7-0003-SM-3NM8M GTEx Tissue Sample Gene Expression Profiles -1.0 -1.79104 CW9019 DepMap CRISPR Gene Dependency 1.0 2.13129 eGFP-FOS_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Ocular cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.163 GTEX-XMD1-0011-R11A-SM-4AT5J GTEx Tissue Sample Gene Expression Profiles 1.0 0.961641 deformed sella turcica HPO Gene-Disease Associations 1.0 null Liver disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.206 BRD-K15358569 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.47046 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YD-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IFT80 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53331 Hyperplasia CTD Gene-Disease Associations 1.0 1.03567 CDX2-21074721-CACO-2-MOUSE ChEA Transcription Factor Targets 2022 1.0 null SRF_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null membrane-bounded organelle LOCATE Curated Protein Localization Annotations 1.0 null Hepatobiliary system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.269 CEBPA-26348894-LIVER-MOUSE ChEA Transcription Factor Targets 2022 1.0 null BRD-K07697589 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.61488 Pancreas TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 BRD-K87754766 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.73493 LS-411N COSMIC Cell Line Gene Mutation Profiles 1.0 null 17683608-TableS2 GeneSigDB Published Gene Signatures 1.0 null THEM4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.16386 GTEX-R55E-0726-SM-48FCZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.57257 BRD-K10135449 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.96549 HDAC2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Hip TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.082 Medulloblastoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.742 H3K4me3_erythroblast_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null SW 1990 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.08935 SMC3_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH69 CCLE Cell Line Gene Mutation Profiles 1.0 null 496100420_PCx_probable Alzheimer's disease_no TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.47609 LNCAP-CLONE-FGC COSMIC Cell Line Gene Mutation Profiles 1.0 null HCC2885 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.6327 SIN3B-21632747-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-SUCS-0006-SM-4DM59 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.92659 GSE116930,GSE116935_1_v_6_hes7_human RummaGEO Gene Perturbation Signatures 1.0 null CALU-6 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.858562 Lung squamous cell carcinoma_LUSC_TCGA-90-A4ED-01A-31R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 layer IIIb of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.2673 H3K4me3_fibroblast of gingiva_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SP4_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SKBR3 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.941741 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3347-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null eggshell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.392309 OE33 CCLE Cell Line Gene CNV Profiles -1.0 -1.38197 hedgehog family protein binding GO Molecular Function Annotations 2015 1.0 null SW 1417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.28308 TP53INP2_OE_GDS5053_312_mouse_Skeletal muscle GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null orbital frontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.85747 Optic cup TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.382 XRCC5 Pathway Commons Protein-Protein Interactions 1.0 null FLI1 ChEA Transcription Factor Targets 1.0 null kidney HPA Tissue Protein Expression Profiles -1.0 -0.897918 PMC6078963-41467_2018_5311_MOESM5_ESM.xlsx-48h_KD_UP_Vs_ATAC-z_e_o_To_AR Rummagene Transcription Factor Associations 2026 1.0 null GTEX-W5X1-2826-SM-3GILM GTEx Tissue Sample Gene Expression Profiles 1.0 2.63243 A3/KAW Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.2525 NCI-H2595 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.848826 Neuroblastoma DisGeNET Gene-Disease Associations 1.0 null PROX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.6782 CLTA Pathway Commons Protein-Protein Interactions 1.0 null Prostate adenocarcinoma_PRAD_TCGA-XQ-A8TA-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_NT2-D1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ventrolateral prefrontal cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.0545 hsa-miR-617 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 Perturb_13715_KO_ASXL3_SRP360138 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.7161 increased leukocyte cell number MPO Gene-Phenotype Associations 1.0 null POLR2A ENCODE Transcription Factor Targets 1.0 null Swim bladder TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.391 NOP10 Pathway Commons Protein-Protein Interactions 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5085-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Acrocallosal syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.031 CRCGN009_HEPG2_24H:D05 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.65957 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19D-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XGQ4-0005-SM-4AT5U GTEx Tissue Sample Gene Expression Profiles -1.0 -1.97829 biological_process GO Biological Process Annotations 2015 1.0 null GTEX-T8EM-0126-SM-4DM5R GTEx Tissue Sample Gene Expression Profiles 1.0 1.48061 PLA2G12A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.24502 Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RH-01A-12R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IGROV-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null MYCN-27167114-CHIP-SEQ-NEUROBLASTOMA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-V955-0005-SM-3P5ZC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.33312 trunk TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.306805 KDM1A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RCM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.45774 abnormality of the uvea HPO Gene-Disease Associations 1.0 null GTEX-REY6-0005-SM-2TF54 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.06035 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YM-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Imaginal disc TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.878 UBB Pathway Commons Protein-Protein Interactions 1.0 null SIN3A_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_kidney epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ZNF770 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.7872 GSE182680,GSE182683_5_v_13_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null PMC8901773-41598_2022_7986_MOESM3_ESM.xls-PIO_vs_LPS-Gene_symbol_ENSEMBL_ID_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null GSE137177_2_v_4_folic acid_mouse RummaGEO Drug Perturbation Signatures -1.0 null NCI-H209 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.48899 Artery - Tibial GTEx Tissue Gene Expression Profiles 2023 1.0 2.23358 GTEX-T2IS-1126-SM-4DM6Z GTEx Tissue Sample Gene Expression Profiles 1.0 1.86224 BRD-K87617154 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.12549 esophageal cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.273308 integument phenotype MPO Gene-Phenotype Associations 1.0 null VIM Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_Adipose Nuclei Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SERBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.70989 Cryptorchidism DisGeNET Gene-Disease Associations 1.0 null Folic Acid CTD Gene-Chemical Interactions 1.0 null all HPO Gene-Disease Associations 1.0 null XRN2-22483619-HELA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null integumentary system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.054533 posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.56213 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4843-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC4965740__F9 PFOCR Pathway Figure Associations 2023 1.0 null GSE110178_4_v_0_tranylcypromine_mouse RummaGEO Drug Perturbation Signatures 1.0 null HT29 BioGPS Cell Line Gene Expression Profiles 1.0 1.09859 Cerebral degeneration DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.075 H3K9me3_erythroblast_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null PMC5743625__F2 PFOCR Pathway Figure Associations 2023 1.0 null H3K4me2_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TRIM28_knockout_302_GSE32224 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.17602 GATA1::TAL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.8234 abnormality of eye movement HPO Gene-Disease Associations 1.0 null CAPAN-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.00335 KRI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15389 SP3_Deficiency_GDS3058_610_mouse_Embryonic heart (day 12.5 C57Bl/6) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null H3K4me3_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null E2F6_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE162739_2_v_1_bap1_mouse RummaGEO Gene Perturbation Signatures 1.0 null A427 DepMap CRISPR Gene Dependency 1.0 3.29569 EIF3H CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52596 hsa-miR-3193 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 hsa-miR-4502 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 GSE172494_3_v_1_nicotinamide_human RummaGEO Drug Perturbation Signatures 1.0 null male reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.631123 SNU407 CCLE Cell Line Gene Mutation Profiles 1.0 null UCHL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32525 GTEX-V955-2526-SM-4JBJG GTEx Tissue Sample Gene Expression Profiles 1.0 1.04278 Acute Myeloid Leukemia_LAML_TCGA-AB-2952-03B-01T-0760-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-P4PP-2426-SM-3P61L GTEx Tissue Sample Gene Expression Profiles 1.0 1.30817 Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4113-01A-01R-1193-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XMD1-2826-SM-4AT5F GTEx Tissue Sample Gene Expression Profiles 1.0 1.12419 hypertelorism HPO Gene-Disease Associations 1.0 null GTEX-WFON-1926-SM-3LK7L GTEx Tissue Sample Gene Expression Profiles 1.0 1.00758 PMC6565568-MGG3-7-e721-s001.doc-0-PAX5_PAX5 Rummagene Transcription Factor Associations 2026 1.0 null H2AFZ_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null spermatogonium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.598067 osteochondrosis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.608885 organelle LOCATE Curated Protein Localization Annotations 1.0 null Gli1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.393 hair cycle GO Biological Process Annotations 2015 1.0 null kyphoscoliosis HPO Gene-Disease Associations 1.0 null abnormal epidermal layer morphology MPO Gene-Phenotype Associations 1.0 null NRL JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.4364 GTEX-RM2N-1326-SM-48FCW GTEx Tissue Sample Gene Expression Profiles 1.0 1.23383 Lung adenocarcinoma_LUAD_TCGA-97-8552-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null thyroid gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.382131 TTF2-22483619-HELA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-T6MN-0326-SM-32PMK GTEx Tissue Sample Gene Expression Profiles 1.0 2.57414 HIST1H1C Pathway Commons Protein-Protein Interactions 1.0 null V Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.00982 LEF1-29337183-MESC-MOUSE-STEM ChEA Transcription Factor Targets 2022 1.0 null BRD-K00191683 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.89039 posteroventral (inferior) parietal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.31915 BRD-K47212522 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.19552 HEY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.907146 PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null PLOD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.00945 PMC10454035__F2 PFOCR Pathway Figure Associations 2024 1.0 null PMC10898159__F3 PFOCR Pathway Figure Associations 2024 1.0 null GTEX-X585-0426-SM-4E3JZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.27167 Organ system benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.81 TP73 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.0648 GTEX-T6MN-0002-SM-3NMAH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03045 throat TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.357802 BRD-K56441027 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.40974 GTEX-RU1J-0826-SM-46MUU GTEx Tissue Sample Gene Expression Profiles 1.0 1.41993 BRD-K51522005 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.16854 mediodorsal nucleus of thalamus_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.19736 ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055944 syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.05258 MTA3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Coarse Facial Features DisGeNET Gene-Phenotype Associations 1.0 null theca cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.567626 Neoplasm Invasiveness HuGE Navigator Gene-Phenotype Associations 1.0 null Granule cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.403 sternum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.242054 Thyroid epithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.232 PBX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.73423 hippocampus (hippocampal formation)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.20517 HS600T CCLE Cell Line Gene Mutation Profiles 1.0 null Kidney Diseases CTD Gene-Disease Associations 1.0 1.01549 GSE126127_2_v_3_prmt1_mouse RummaGEO Gene Perturbation Signatures -1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.927091 CRCGN011_HEPG2_24H:H07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.5066 thioridazine-5921 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-W5X1-0001-SM-3P61V GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08915 TBP ENCODE Transcription Factor Targets 1.0 null identification GeneRIF Biological Term Annotations 1.0 null GTEX-SUCS-0002-SM-3NMAJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.36604 PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_downregulated_genes-Unnamed_6_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null GSE248858_5_v_2_tcpobop_mouse RummaGEO Drug Perturbation Signatures 1.0 null Lung adenocarcinoma_LUAD_TCGA-86-A4P8-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QLQW-0005-SM-2S1RA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.21449 GTEX-OXRN-2626-SM-48TBX GTEx Tissue Sample Gene Expression Profiles 1.0 0.930289 short distal phalanx of the thumb HPO Gene-Disease Associations 1.0 null Short 4Th Metacarpal DisGeNET Gene-Phenotype Associations 1.0 null Obstructive hydrocephalus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.194 PMC7401461-iovs-61-3-10_s001.xlsx-Sheet1-SRY_SRY Rummagene Transcription Factor Associations 2026 1.0 null BRD-K48129913 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.31539 CardiacMyocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.52652 supernumerary bones of the axial skeleton HPO Gene-Disease Associations 1.0 null Msgn1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.286 reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.807716 ventrolateral prefrontal cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.24686 DNAJB1 Hub Proteins Protein-Protein Interactions 1.0 null CiliaryGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.00835 REST ENCODE Transcription Factor Targets 1.0 null GTEX-TML8-0926-SM-4DXSJ GTEx Tissue Sample Gene Expression Profiles 1.0 2.22872 Brain Lower Grade Glioma_LGG_TCGA-P5-A5F2-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-A46H-01A-31R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inner CP in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.849945 BRD-K07351191 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00317 LAMA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.04365 18801183-SuppTable1 GeneSigDB Published Gene Signatures 1.0 null abnormality of the falx cerebri HPO Gene-Disease Associations 1.0 null Liver cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.201 NCI-N417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.85233 fetal alcohol spectrum disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.383337 PMC5999604__F2 PFOCR Pathway Figure Associations 2023 1.0 null H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null intestinal polyp HPO Gene-Disease Associations 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null blast cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.067381 BRD-K23975481 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.87661 YY1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Craniosynostosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.101 BRD-K30895360 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.22256 abnormal facial shape HPO Gene-Disease Associations 1.0 null primary auditory cortex (core)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.12379 H3K4me3_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_HepG2_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null BRD-K80724940 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.67564 496100402_FWM_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.24792 mainolfactoryepithelium.MOE. BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.89527 QDPR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49538 NCI-H1092 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.17931 GTEX-WRHU-0926-SM-4E3IG GTEx Tissue Sample Gene Expression Profiles 1.0 0.929715 superior colliculus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.838136 TEAD4_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-S4Q7-1226-SM-4AD5I GTEx Tissue Sample Gene Expression Profiles 1.0 1.31413 PMC12178829-mmc4.xlsx-Sheet_4-MEG3-KD_Up-GeneName_AR Rummagene Transcription Factor Associations 2026 1.0 null SRSF12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.11414 HCC2998 BioGPS Cell Line Gene Expression Profiles -1.0 -1.40234 Lens fiber TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.71 Strabismus DisGeNET Gene-Disease Associations 1.0 null Benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.836 HNRNPU Pathway Commons Protein-Protein Interactions 1.0 null C32 CCLE Cell Line Gene Mutation Profiles 1.0 null BRD-K19103580 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.11799 primary visual cortex (striate cortex, area V1/17)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.42046 PRPF19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.28571 EVSA-T COSMIC Cell Line Gene Mutation Profiles 1.0 null Allantois TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.521 RAB11FIP5 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_5231_KO_Kmt5c_SRP194976 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 CTCF_lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mRNA_SETDB1_19884255 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null HCC4006 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.98239 BRD-K38519440 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.46049 Uterine Carcinosarcoma_UCS_TCGA-NA-A4R1-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NUBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.79997 Prostate adenocarcinoma_PRAD_TCGA-YL-A8SK-01B-21R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null L-363 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.74159 GTEX-T6MN-2526-SM-32PMN GTEx Tissue Sample Gene Expression Profiles 1.0 0.953178 Stat2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 66.4653 Perturb_15694_OE_NOAT113026_SRP212748 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.72141 hsa-miR-4270 TargetScan Predicted Conserved microRNA Targets 1.0 0.90397 HCC1569 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.714323 Pronephric duct TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.941 GTEX-RM2N-0008-SM-48FF3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07287 Dlx5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 30.4368 NCI-H1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.916999 GTEX-XBEC-0126-SM-4GIDT GTEx Tissue Sample Gene Expression Profiles 1.0 1.3338 TE-9 COSMIC Cell Line Gene Mutation Profiles 1.0 null SNUC1 CCLE Cell Line Gene Expression Profiles 1.0 1.94139 GTEX-Q734-1426-SM-48TZQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.839744 H3K27me3_iPS-20b Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_GM12864_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Hypotrichosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.776 H3K4me3_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NR1D2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.50411 H3K4me3_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K13309514 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.27686 Hirschsprung's disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.409 HAUS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.04457 NUP210 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.02741 NCI-H1648 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.973244 ovary TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.235748 PMC4920139__F1 PFOCR Pathway Figure Associations 2024 1.0 null GSE94849_6_v_0_pinometostat_human RummaGEO Drug Perturbation Signatures 1.0 null Cuticle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.292 mode of inheritance HPO Gene-Disease Associations 1.0 null aplasia/hypoplasia of the extremities HPO Gene-Disease Associations 1.0 null Inner nuclear layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.942 NCIH1573 DepMap CRISPR Gene Dependency 1.0 2.31146 Tooth germ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.709 abnormal dermal layer morphology MGI Mouse Phenotype Associations 2023 1.0 null Carcinoma, Basal Cell CTD Gene-Disease Associations 1.0 2.88009 increased hematopoietic cell number MPO Gene-Phenotype Associations 1.0 null LMCD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.19843 Intravenous leiomyomatosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.024 Blastopore TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.705 NFYB_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-UPJH-0006-SM-3GACW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.01125 CAPAN-1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.913 intrinsic component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 CALU-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.874053 Nephrotome TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.656 FAM181B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11795 UBXN2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.29682 Adenocarcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.606 BRD-K66700691 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.51948 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19P-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ANXA2 Pathway Commons Protein-Protein Interactions 1.0 null neoplasm of the skin HPO Gene-Disease Associations 1.0 null EGR1-20690147-ERYTHROLEUKEMIA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null nevoid GeneRIF Biological Term Annotations 1.0 null motor nucleus of trigeminal nerve, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.963765 GSE242199_2_v_0_ntrk2_human RummaGEO Gene Perturbation Signatures -1.0 null MAX_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SUCS-1326-SM-4DM5T GTEx Tissue Sample Gene Expression Profiles 1.0 1.42003 CRCGN015_MCF10A_48H:N22 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.24576 H3K4me1_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MXI1 ENCODE Transcription Factor Targets 1.0 null H3K4me2_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PMC5999604__F2 PFOCR Pathway Figure Associations 2024 1.0 null COLO205 DepMap CRISPR Gene Dependency 1.0 2.44854 dentate gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.37144 Nkx3-2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.1323 Bone disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.444 Ku70:Ku80 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.756 HT55 COSMIC Cell Line Gene Mutation Profiles 1.0 null abnormality of the cerebrum HPO Gene-Disease Associations 1.0 null fastigial nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.24502 posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.883916 VSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.6462 hyoscyamine-5524 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null ischemic bone disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.231795 GTEX-Q2AG-0326-SM-48U1O GTEx Tissue Sample Gene Expression Profiles 1.0 0.876572 diethylstilbestrol-4547 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null HCC-827 COSMIC Cell Line Gene Mutation Profiles 1.0 null tooth enamel TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.366381 primary auditory cortex (core)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.870421 abnormal eye physiology HPO Gene-Disease Associations 1.0 null CRCGN008_HEPG2_24H:O05 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.06065 GTEX-R55F-0005-SM-2TF4W GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11441 HOXB4_02_64 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.59735 H3K4me2_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-P4PP-0326-SM-33HC4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03187 NCI-H2081 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.25195 abnormal genital system morphology GWASdb SNP-Phenotype Associations 1.0 0.115013 H3K27ac_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null midbrain reticular formation, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.1818 integral component of membrane GO Cellular Component Annotations 2015 1.0 null H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PF-00562151-00-5922 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-U3ZH-1626-SM-3DB74 GTEx Tissue Sample Gene Expression Profiles 1.0 1.38868 Saccule TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.815 Perturb_1686_OE_Mnx1_SRP373412 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 Split septin rings COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.761 H2AFZ_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CBX3_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null receptor binding GO Molecular Function Annotations 2015 1.0 null Brain_Germinal_Matrix Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 0.975076 thyroid cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.391141 Lung adenocarcinoma_LUAD_TCGA-97-A4M7-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_16502_KD_ASCL1_SRP325888 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.7902 Stalk cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.657 USP24 Pathway Commons Protein-Protein Interactions 1.0 null CTCF ChEA Transcription Factor Targets 1.0 null GSE162276_4_v_0_pparg_mouse RummaGEO Gene Perturbation Signatures 1.0 null ZNF263_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormality of the stomach HPO Gene-Disease Associations 1.0 null Duckembryo TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.575 NCIH1581 DepMap CRISPR Gene Dependency 1.0 2.61974 PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_49_KLF4 Rummagene Transcription Factor Associations 2026 1.0 null aplasia/hypoplasia of the ribs HPO Gene-Disease Associations 1.0 null KMRC1 DepMap CRISPR Gene Dependency 1.0 3.37313 Protein phosphatase 4 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.344 membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.209513 PMC3720582__F1 PFOCR Pathway Figure Associations 2024 1.0 null pretectal region Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.11761 outer SZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.02853 CTCF_BJ_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null forelimb TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.077942 RUVBL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36988 primary auditory cortex (core)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.959896 mRNA_GATA3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Perturb_9503_KO_Crif1_SRP259100 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -6.93572 Bone development disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.473 Sporangium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.299 short distal phalanx of finger HPO Gene-Disease Associations 1.0 null Vertebral Wedging DisGeNET Gene-Disease Associations 1.0 null valproic acid-4438 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Dlx2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 30.201 gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.576015 Class B/2 (Secretin family receptors) Reactome Pathways 2024 1.0 null PRMT5 Pathway Commons Protein-Protein Interactions 1.0 null ACTB Pathway Commons Protein-Protein Interactions 1.0 null GTEX-N7MT-1026-SM-3TW8T GTEx Tissue Sample Gene Expression Profiles 1.0 1.08997 DNAJA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15465 GSE242096,GSE242098_1_v_0_med1_mouse RummaGEO Gene Perturbation Signatures -1.0 null smith-lemli-opitz syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.531154 GSE111660_4_v_3_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null susceptibility GeneRIF Biological Term Annotations 1.0 null eye TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.350001 hsa-miR-4423-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 negative regulation of signal transduction GO Biological Process Annotations 2025 1.0 null 18787207-Table1 GeneSigDB Published Gene Signatures 1.0 null abnormality of the skull HPO Gene-Disease Associations 1.0 null GSE92589_0_v_1_sirolimus_mouse RummaGEO Drug Perturbation Signatures -1.0 null PMC7594423-12915_2020_895_MOESM13_ESM.xlsx-Table_S6D-Table_S6D_-_Differentially_Expressed_genes_shared_between_BRCA_TRIM25_amp_and_STAD_CIC_Del_CIC Rummagene Transcription Factor Associations 2026 1.0 null Reflex, Abnormal CTD Gene-Disease Associations 1.0 1.2059 Scoliosis, Unspecified DisGeNET Gene-Disease Associations 1.0 null Cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.414 Protein phosphatase type 2A complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.483 POLR2A_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Carcinoma, Basal Cell HuGE Navigator Gene-Phenotype Associations 1.0 null H3K4ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null VZ in rostral cingulate neocortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.993388 GTEX-QLQW-1426-SM-2S1QU GTEx Tissue Sample Gene Expression Profiles 1.0 1.11224 LPAR4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26599 GSE196505,GSE196507_1_v_2_kdm2b_human RummaGEO Gene Perturbation Signatures -1.0 null Neuroepithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.416 HCC38 CCLE Cell Line Gene CNV Profiles 1.0 1.75314 germ cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.699035 RB1_KD_GSE50532_593_human_OSTEOBLASTS GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VH-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null decreased hemoglobin content MGI Mouse Phenotype Associations 2023 1.0 null Cranium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.955 GTEX-S7SE-2526-SM-2XCDL GTEx Tissue Sample Gene Expression Profiles 1.0 0.892362 Variable Expressivity DisGeNET Gene-Phenotype Associations 1.0 null MOLT4 BioGPS Cell Line Gene Expression Profiles 1.0 1.53978 Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1Z7-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE152441,GSE152442_6_v_5_folic acid_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-QCQG-0008-SM-48U2G GTEx Tissue Sample Gene Expression Profiles -1.0 -0.849982 HUNS1 DepMap CRISPR Gene Dependency 1.0 2.38427 Mouth TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 P12-ICHIKAWA COSMIC Cell Line Gene Mutation Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WO-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HIST2H2AB Pathway Commons Protein-Protein Interactions 1.0 null GTEX-WFON-0005-SM-3NMC9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.2813 PMC4848008__F2 PFOCR Pathway Figure Associations 2023 1.0 null POLR2A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE242199_9_v_7_ntrk2_human RummaGEO Gene Perturbation Signatures -1.0 null PMC9794594-DataSheet_1.xlsx-ST12-Unnamed_1_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null ChIP_SALL4_18804426 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Patched InterPro Predicted Protein Domain Annotations 1.0 null enlarged urinary bladder IMPC Knockout Mouse Phenotypes 1.0 null PMC3691204__F1 PFOCR Pathway Figure Associations 2024 1.0 null nucleus subceruleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.858249 GTEX-PLZ5-1526-SM-3P5ZX GTEx Tissue Sample Gene Expression Profiles 1.0 1.43709 GSE180200,GSE180201_5_v_1_qpctl_mouse RummaGEO Gene Perturbation Signatures -1.0 null MEOX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.80627 Epibranchial TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.752 membrane part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83T-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Leydig precursor cell_Fetal gonad_Human CellMarker Gene-Cell Type Associations 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6789-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TP53 ChEA Transcription Factor Targets 1.0 null MTA3 ENCODE Transcription Factor Targets 1.0 null H3K4me3_cardiac mesoderm_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null CLEC11A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.00559 Adult Rhabdomyosarcoma DisGeNET Gene-Disease Associations 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-2K-A9WE-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null abnormality of the cardiovascular system HPO Gene-Disease Associations 1.0 null hsa-miR-195 TargetScan Predicted Conserved microRNA Targets 1.0 0.078844 496100436_FWM_no dementia_no TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.15854 trachea BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.03205 POLR2AphosphoS5_neural cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SUPV3L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.36597 RFX5 ENCODE Transcription Factor Targets 1.0 null PSN1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.25134 GTEX-NL3H-0006-SM-2I3FW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16732 BRD-K61807670 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.56256 LY6G5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.06719 internal female genital organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.58242 mRNA_SOX2_16767105 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null BRD-K84077642 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.48568 SLC25A24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.49448 MOLM-16 COSMIC Cell Line Gene Mutation Profiles 1.0 null u266 HPA Cell Line Gene Expression Profiles 1.0 0.836964 H3F3A Pathway Commons Protein-Protein Interactions 1.0 null specific developmental disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.053654 abnormality of the distal phalanx of the thumb HPO Gene-Disease Associations 1.0 null Lung adenocarcinoma_LUAD_TCGA-NJ-A55A-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U3ZN-1926-SM-4DXSG GTEx Tissue Sample Gene Expression Profiles 1.0 0.94496 CEBPE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.53998 ovary GTEx Tissue Gene Expression Profiles 1.0 1.46272 T-47D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07691 CALU-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.859689 KPNRTBM1 CCLE Cell Line Gene CNV Profiles -1.0 -2.03888 CRCGN016_MCF10A.WT.HP_24H:L10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.05406 GTEX-R55C-1926-SM-2TF4K GTEx Tissue Sample Gene Expression Profiles 1.0 1.13566 Thyroid nodule TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.309 H3K9ac_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null YY1_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null sk-n-sh cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.23781 genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.760231 E2F6 ENCODE Transcription Factor Targets 1.0 null YMB1 CCLE Cell Line Gene CNV Profiles -1.0 -1.52272 NCI-H520 COSMIC Cell Line Gene CNV Profiles 1.0 4.51153 BRD-K35133923 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.07487 SA1-27219007-CHIP-SEQ-ERYTHROID-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-RTLS-2326-SM-46MUH GTEx Tissue Sample Gene Expression Profiles 1.0 1.15625 frontal bossing HPO Gene-Disease Associations 1.0 null GTEX-WCDI-0005-SM-3NB2M GTEx Tissue Sample Gene Expression Profiles -1.0 -1.15593 Perturb_4787_KD_Akap8_SRP075747 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.88817 GSE248858_4_v_3_tcpobop_mouse RummaGEO Drug Perturbation Signatures 1.0 null Gill arch TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.156 Rhabdomyosarcoma DisGeNET Gene-Disease Associations 1.0 null CB-83-LF14_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.205735 BT549 DepMap CRISPR Gene Dependency 1.0 2.46823 GSE127970_2_v_3_ebf1_mouse RummaGEO Gene Perturbation Signatures -1.0 null BCL3 ENCODE Transcription Factor Targets 1.0 null Retinal cell cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.056 regulation of cellular process GO Biological Process Annotations 2015 1.0 null NCIH520 CCLE Cell Line Gene CNV Profiles 1.0 3.2803 GSE182680,GSE182683_10_v_3_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null GSE189609_1_v_2_hax1_human RummaGEO Gene Perturbation Signatures -1.0 null craniofacial region TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.421148 Parenchyma of thyroid gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.518 medial mammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.98471 outer SZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.950828 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29G-06A-12R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FAM118B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32706 oocyte BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.43071 holoprosencephaly DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.327375 COLO 320DM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.29681 BRD-K54881917 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.60378 KLF9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 56.8742 Uterine seam cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.643 BRD-K41311678 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.76351 SMAD1-18555785-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null BRD-K07390518 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.62737 Carcinoma, Ovarian Epithelial DisGeNET Gene-Disease Associations 1.0 null Experimental Organism Basal Cell Carcinoma DisGeNET Gene-Phenotype Associations 1.0 null IGF2BP2 Pathway Commons Protein-Protein Interactions 1.0 null Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z4-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K45138525 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.07737 rostral subdivision of paraventricular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.03387 H3K4me3_foreskin fibroblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null FOSL1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null GSE145915_5_v_4_pcm1_mouse RummaGEO Gene Perturbation Signatures 1.0 null kasugamycin LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.80136 Pharyngeal arch cartilage TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.017 KDM2B-26808549-CHIP-SEQ-K562-HUMAN ChEA Transcription Factor Targets 2022 1.0 null BRD-K87053028 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.01965 Aplastic anemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.018 Intraciliary transport particle B COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.58 abnormal eye morphology HPO Gene-Disease Associations 1.0 null hippocampus (hippocampal formation)_11 yrs_F_12289 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.45913 MYH1 Pathway Commons Protein-Protein Interactions 1.0 null outer CP in caudal cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.11732 H3K27me3_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null medial superior olive Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.916979 DGKE Pathway Commons Protein-Protein Interactions 1.0 null GTEX-S4Z8-0006-SM-3K2AQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.955384 H3K4me3_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null abnormality of the parietal bone HPO Gene-Disease Associations 1.0 null KIF2C Pathway Commons Protein-Protein Interactions 1.0 null cerebellar cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.70069 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A6-01A-11R-A22L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Dental papilla TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.926 choroid plexus of the lateral ventricle Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.52318 mRNA_ZSCAN4C_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null leukocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.058417 BRD-K22748970 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.88357 primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.18953 BRD-K18888894 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.01752 Drug-Induced Liver Injury CTD Gene-Disease Associations 1.0 1.21567 AGO1_02_95 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.59012 Nr5a1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.4537 Fetal_Brain_Female Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 1.96892 H3K4me3_G1E-ER4_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_megakaryocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SUIT2 DepMap CRISPR Gene Dependency 1.0 2.26215 GTEX-U4B1-0326-SM-3DB8K GTEx Tissue Sample Gene Expression Profiles -1.0 -0.99592 GTEX-T5JC-2326-SM-32PMR GTEx Tissue Sample Gene Expression Profiles 1.0 0.877639 Neurofibroma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.093 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4971-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SYK_knockdown_280_GDS3609 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.67848 GTEX-VUSG-2726-SM-4KKZJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.43432 GSE94814_1_v_0_reck_mouse RummaGEO Gene Perturbation Signatures -1.0 null Ovarian Carcinoma DisGeNET Gene-Disease Associations 1.0 null mrc9 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.851 SMAD4-21799915-A2780-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-WFON-0226-SM-3GIKR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.855835 PMC5999604__F3 PFOCR Pathway Figure Associations 2023 1.0 null NCI-H1703 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.877032 Nasal Bridge Wide DisGeNET Gene-Phenotype Associations 1.0 null GTEX-S7SE-0008-SM-33HB1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.20227 aplasia/hypoplasia of the phalanges of the hand HPO Gene-Disease Associations 1.0 null Supratentorial primitive neuroectodermal tumor DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.215 ZDHHC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.48274 GTEX-WCDI-0002-SM-3P61U GTEx Tissue Sample Gene Expression Profiles -1.0 -1.22822 Spina Bifida DisGeNET Gene-Disease Associations 1.0 null abnormality of the calvaria HPO Gene-Disease Associations 1.0 null LU-134-A COSMIC Cell Line Gene Mutation Profiles 1.0 null papillary carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.180937 Pulmonary Hypertension DisGeNET Gene-Disease Associations 1.0 null BRD-K05051664 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.40397 Perturb_13716_KO_BAP1_SRP360138 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.00594 GTEX-OXRL-0008-SM-3NB29 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.985063 BRD-K97576000 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.39449 POLR2A_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K22863062 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.21556 GTEX-XBED-0006-SM-47JXO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.50335 Mitotic spindle midzone COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.537 smoothened binding GO Molecular Function Annotations 2015 1.0 null PMC10273753-12920_2023_1570_MOESM1_ESM.docx-0-POU5F1_POU5F1 Rummagene Transcription Factor Associations 2026 1.0 null PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_7_CCF-Affected_Genes_PITX1 Rummagene Transcription Factor Associations 2026 1.0 null Oligodendroglioma DisGeNET Gene-Disease Associations 1.0 null GSE210101,GSE210114_7_v_3_urod_human RummaGEO Gene Perturbation Signatures -1.0 null Breast carcinoma ClinVar Gene-Phenotype Associations 2025 1.0 null GTEX-XOTO-2926-SM-4B65G GTEx Tissue Sample Gene Expression Profiles 1.0 0.830982 HNFA-21074721-CACO-2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null BRD-K40418847 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05889 PMC6689010-41467_2019_11551_MOESM6_ESM.xlsx-d-Is_the_gene_a_target_of_SMAD1-4_SMAD1 Rummagene Transcription Factor Associations 2026 1.0 null Hereditary Hemochromatosis DisGeNET Gene-Disease Associations 1.0 null Telecanthus DisGeNET Gene-Phenotype Associations 1.0 null PCI-15A COSMIC Cell Line Gene Mutation Profiles 1.0 null leg TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.088192 Neural retina TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.106 NCL Pathway Commons Protein-Protein Interactions 1.0 null H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K31218318 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.15452 Throat TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 DHRS2 Pathway Commons Protein-Protein Interactions 1.0 null GSE150669_2_v_3_roxadustat_mouse RummaGEO Drug Perturbation Signatures -1.0 null HIST1H4F Pathway Commons Protein-Protein Interactions 1.0 null ZNF320 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 157.073 PRKACB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.4058 H3K4me1_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-RNOR-2426-SM-48FDY GTEx Tissue Sample Gene Expression Profiles 1.0 1.13074 JUN JASPAR Predicted Transcription Factor Targets 1.0 null organism form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.07574 PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_29_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null GLI proteins bind promoters of Hh responsive genes to promote transcription Reactome Pathways 2014 1.0 null BRD-K26237438 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.28058 PMC10898159__F2 PFOCR Pathway Figure Associations 2024 1.0 null CTCF_HepG2_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null DOV13 DepMap CRISPR Gene Dependency 1.0 3.10631 H3K27me3_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE163275_1_v_0_irf8_human RummaGEO Gene Perturbation Signatures 1.0 null hsa-miR-548ae TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 CARMIL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.05381 KPL-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.04893 GSE101336_1_v_0_decitabine_mouse RummaGEO Drug Perturbation Signatures -1.0 null PMC5743625__F2 PFOCR Pathway Figure Associations 2024 1.0 null GTEX-OXRO-0006-SM-2I5EM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.50338 H3K4me3_skeletal muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE184210_0_v_2_glucagon_mouse RummaGEO Drug Perturbation Signatures -1.0 null aortic root TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.214576 FAM91A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.00042 HCC1438 CCLE Cell Line Gene Mutation Profiles 1.0 null BL-41 GDSC Cell Line Gene Expression Profiles 1.0 2.03105 Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OQ-11A-21R-A220-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WL46-0426-SM-3TW8J GTEx Tissue Sample Gene Expression Profiles 1.0 1.91541 CAMA1 CCLE Cell Line Gene CNV Profiles -1.0 -1.73957 H3K4me1_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE150669_2_v_1_roxadustat_mouse RummaGEO Drug Perturbation Signatures -1.0 null GTEX-PW2O-1426-SM-48TCD GTEx Tissue Sample Gene Expression Profiles 1.0 1.83719 Skin epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.996 SKNBE2 CCLE Cell Line Gene CNV Profiles -1.0 -1.65123 Prostate adenocarcinoma_PRAD_TCGA-XQ-A8TB-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Feather TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.237 beta-catenin-TCF complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.822 hsa-miR-584 TargetScan Predicted Conserved microRNA Targets 1.0 0.632343 BRD-K54003568 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.02216 Leaf collar TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.635 inferior olive, medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.941285 D502MG DepMap CRISPR Gene Dependency 1.0 2.91197 EPS15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.933 GTEX-S7SE-0726-SM-2XCD7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.32095 GTEX-RU72-0011-R11A-SM-2TF6J GTEx Tissue Sample Gene Expression Profiles 1.0 0.835354 TEN CCLE Cell Line Gene Mutation Profiles 1.0 null abnormal granulocyte morphology MPO Gene-Phenotype Associations 1.0 null neuroepithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.33413 GTEX-WFG8-0006-SM-3GIKS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.70861 H3K4me3_cardiac fibroblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null YMB-1-E Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.59967 HMEL CCLE Cell Line Gene Expression Profiles 1.0 2.98706 YWHAH Pathway Commons Protein-Protein Interactions 1.0 null abnormality of facial skeleton HPO Gene-Disease Associations 1.0 null Schwalie et al.Nature.P3_Adipose tissue_Mouse CellMarker Gene-Cell Type Associations 1.0 null wide nasal bridge HPO Gene-Disease Associations 1.0 null UBLC1 DepMap CRISPR Gene Dependency 1.0 3.26784 JEKO-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Oculo-Dento-Digital Syndrome DisGeNET Gene-Disease Associations 1.0 null primary auditory cortex (core)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.62058 SP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.35175 GTEX-PVOW-0006-SM-3NMB8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.932104 Cataract DisGeNET Gene-Disease Associations 1.0 null H3K4me3_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.930772 POU5F1-18358816-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null 496100296_PCx_possible Alzheimer's disease_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.04027 BRD-K85059356 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.34724 BRD-K91339294 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.19522 ZNF174 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.91325 GSE162892_4_v_0_isox_human RummaGEO Drug Perturbation Signatures 1.0 null Palate TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.604 Primary immunodeficiency disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.085 H3K4me3_GM12875_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null abnormality of the female genitalia HPO Gene-Disease Associations 1.0 null MAX_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTF2F1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null aplasia/hypoplasia affecting bones of the axial skeleton HPO Gene-Disease Associations 1.0 null Joubert syndrome 32 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.696 H3K4me1_erythroblast_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null BRD-K20829034 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.35672 RAD21_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cyclin B1-CDK1 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.568 Pax7 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.2685 B-50 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.746 GTEX-O5YT-0008-SM-4E3IQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.1185 PMC3084000__AF1 PFOCR Pathway Figure Associations 2023 1.0 null GTEX-U4B1-1526-SM-4DXSL GTEx Tissue Sample Gene Expression Profiles 1.0 1.26241 GTEX-S33H-0126-SM-4AD62 GTEx Tissue Sample Gene Expression Profiles 1.0 2.5028 SMO Pathway Commons Protein-Protein Interactions 1.0 null hsa-miR-214 TargetScan Predicted Conserved microRNA Targets 1.0 0.187098 ROCK1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-W5X1-2626-SM-4LMI8 GTEx Tissue Sample Gene Expression Profiles 1.0 0.980026 External ectoderm TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.911 roles GeneRIF Biological Term Annotations 1.0 null nucleus subceruleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.997771 mediodorsal nucleus of thalamus_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.65848 KPNYN CCLE Cell Line Gene Expression Profiles 1.0 1.89249 BRD-K82882121 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.33087 GTEX-N7MS-2526-SM-2D7W3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.854656 PANC 03.27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.12467 GATA6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.08079 RHOT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.13384 TBX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.089 HT144SKINFV2 DepMap CRISPR Gene Dependency 1.0 2.79508 BRD-K41498330 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.81989 GSE48812_3_v_1_sulforaphane_human RummaGEO Drug Perturbation Signatures 1.0 null dorsal subdivision of VLC Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.02714 BRD-K18865369 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.24214 Spinal Fusion DisGeNET Gene-Disease Associations 1.0 null cleft upper lip HPO Gene-Disease Associations 1.0 null H3K4me3_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-V1-A8MM-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Anaplasia DisGeNET Gene-Disease Associations 1.0 null EVI5L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59944 NCI-H1299 GDSC Cell Line Gene Expression Profiles -1.0 -1.60424 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4819-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC5288170__F1 PFOCR Pathway Figure Associations 2023 1.0 null ZNF589 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.00184 GSE113329,GSE113335_2_v_4_taf6l_mouse RummaGEO Gene Perturbation Signatures -1.0 null lens TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.117482 skin lesions MPO Gene-Phenotype Associations 1.0 null LDHB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50161 DNM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.18047 Inflammation CTD Gene-Disease Associations 1.0 1.42508 Metabolic disorders of biological oxidation enzymes Reactome Pathways 2014 1.0 null H3K4me3_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null V, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.2904 EGR1-20690147-ERYTHROLEUKEMIA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null head and neck cancer GWASdb SNP-Disease Associations 1.0 0.739121 T98G Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.51461 GSE182680,GSE182683_5_v_2_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null H3K4me1_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Mesenchymal cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.691 GSE193282_3_v_1_cd44_mouse RummaGEO Gene Perturbation Signatures -1.0 null Malignant astrocytoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.543 TCERG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98092 496100355_HIP_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.05251 SUM44PE Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.16759 Adult medulloblastoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.409 alacrima, achalasia, and impaired intellectual development syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.079 Thyroid gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.739 GTEX-N7MS-0008-SM-4E3JI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13049 H3K4me3_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.49157 G112 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.51461 TYKNU CCLE Cell Line Gene CNV Profiles 1.0 1.4398 H3K4me2_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Rectal Mucosa Donor 31 Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 1.01346 SAP30_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE205070_2_v_5_mertk_mouse RummaGEO Gene Perturbation Signatures -1.0 null EEF1G CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -7.82121 ventrolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.930206 mandibular prognathia HPO Gene-Disease Associations 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A6W2-06A-22R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE198165,GSE198166_6_v_10_zfp266_mouse RummaGEO Gene Perturbation Signatures -1.0 null CRCGN016_MCF10A.WT.HP_24H:P11 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.3801 BACH1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE124375_13_v_0_chd2_mouse RummaGEO Gene Perturbation Signatures -1.0 null LXFL529 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.2525 BHLHE22 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.5717 NSMCE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74991 THP1 CCLE Cell Line Gene CNV Profiles 1.0 1.46276 H3K4me1_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Liver carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.089 hemivertebrae HPO Gene-Disease Associations 1.0 null muscular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05318 hsa-miR-424 TargetScan Predicted Conserved microRNA Targets 1.0 0.078844 abnormal metacarpal morphology HPO Gene-Disease Associations 1.0 null CAL33 CCLE Cell Line Gene Expression Profiles -1.0 -1.60221 inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.10311 MMS22L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25164 BRD-K95323025 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.20288 primary auditory cortex (core)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.14171 developmental GAD High Level Gene-Disease Associations 1.0 0.293278 H3K4me3_Brain Substantia Nigra Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MATCAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.57087 spinalcordupper BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.11983 H3K4me2_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Hedgehog Signaling Pathway(Mus musculus) WikiPathways Pathways 2014 1.0 null Pathways in cancer KEGG Pathways 2026 1.0 null CRCGN017_MCF10A.WT.HP_24H:C21 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.4668 RAD21_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null intrinsic component of membrane GO Cellular Component Annotations 2015 1.0 null GTEX-PLZ4-2826-SM-3P617 GTEx Tissue Sample Gene Expression Profiles 1.0 1.14897 RERF-LC-KJ Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07691 H3K4me3_Stomach Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null THRAP3 Pathway Commons Protein-Protein Interactions 1.0 null H3K27ac_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TAF1_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KE37 DepMap CRISPR Gene Dependency 1.0 4.77917 Thyroid gland medullary carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.494 Hepatomegaly CTD Gene-Disease Associations 1.0 1.19999 skin development GO Biological Process Annotations 2015 1.0 null Hedgehog 'on' state Reactome Pathways 2014 1.0 null PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Significant_DE_genes_in_AKT1_vs_KLF4_meningiomas_KLF4 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-X585-0002-SM-46MVA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.994646 Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3WC-11A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K92291448 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.23568 GTEX-WHSB-0005-SM-3LK7C GTEx Tissue Sample Gene Expression Profiles -1.0 -0.861338 C32 COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC9038526-mmc1.xlsx-postCOVID_ctr_vs_LPS-symbols_98_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null CHD2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Stomodeum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.165 NRF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.32044 Perturb_15897_KD_GLI1_SRP241956 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 CHD1 ENCODE Transcription Factor Targets 1.0 null keratocystic odontogenic tumor HPO Gene-Disease Associations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TM-A7C3-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-86-8671-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ES-I3 Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -0.953698 GSE124410_6_v_4_stk40_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE248858_4_v_7_tcpobop_mouse RummaGEO Drug Perturbation Signatures 1.0 null GTEX-XPT6-0001-SM-4B64G GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13027 H3K4me3_erythroblast_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null NEMF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.05919 GTEX-S95S-0002-SM-3NM8K GTEx Tissue Sample Gene Expression Profiles -1.0 -2.32605 Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20Q-11A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XOTO-0006-SM-4B64T GTEx Tissue Sample Gene Expression Profiles -1.0 -1.51353 SG in caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.836556 BRD-K29298614 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.2784 GSE102870_1_v_2_nr1h4_human RummaGEO Gene Perturbation Signatures -1.0 null Feather barbs TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.505 H3K4me3_WERI-Rb-1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QXCU-0126-SM-2TC5Q GTEx Tissue Sample Gene Expression Profiles 1.0 2.43425 Basosquamous carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.284 oral mucosa HPA Tissue Protein Expression Profiles 1.0 0.96344 PMC6279925__F4 PFOCR Pathway Figure Associations 2024 1.0 null POLR2A_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Orbital Separation Excessive DisGeNET Gene-Phenotype Associations 1.0 null EGR2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.5116 CRCGN013_HEPG2_24H:H15 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.72261 GTEX-PLZ4-0006-SM-2S1NY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908218 Ski complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.18 abnormality of the testis GWASdb SNP-Phenotype Associations 1.0 0.33716 anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.29894 Thyroid Carcinoma DisGeNET Gene-Disease Associations 1.0 null TK-10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01239 ventrolateral prefrontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.17447 mRNA_TCF3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null neoplasm of the genitourinary tract HPO Gene-Disease Associations 1.0 null SPTSSB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.14012 BRD-K82440152 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.26703 Chondrosarcoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.216 H2AFZ_B cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SK-MES-1 GDSC Cell Line Gene Expression Profiles 1.0 2.12611 BRD-K14671528 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.06098 CORL47 CCLE Cell Line Gene CNV Profiles -1.0 -1.46958 ERICH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0047 PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_71_KLF4 Rummagene Transcription Factor Associations 2026 1.0 null periventricular nucleus, preoptic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.53726 Perturb_6737_KD_PAF1_SRP103746 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.20719 BRD-K11474067 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.38162 neoplasm of the genitourinary tract GWASdb SNP-Phenotype Associations 1.0 0.185662 orbital cyst HPO Gene-Disease Associations 1.0 null Medulloblastoma DisGeNET Gene-Disease Associations 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MI-06A-11R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Neuroblastoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.074 H3K4me2_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC11873652-mmc1.pdf-0-AR_AR Rummagene Transcription Factor Associations 2026 1.0 null POLR2J CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.49903 BCP1 CCLE Cell Line Gene Mutation Profiles 1.0 null interpeduncular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.53311 TRIM28_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4703-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 Brachycephaly DisGeNET Gene-Disease Associations 1.0 null Nerve sheath TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.956 IALM CCLE Cell Line Gene CNV Profiles 1.0 1.50665 GTEX-SSA3-0008-SM-47JWJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.825864 CTCF_MCF-7_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null PIK3CA_mutant_27_GDS4053 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.6563 KNS-62 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.78508 increased fasting circulating glucose level MGI Mouse Phenotype Associations 2023 1.0 null SNRPD1 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K47707657 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.51134 GLIS2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 56.2492 ZNF22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.98154 CTCF_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-2467-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 TBR1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.3586 Heart TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 YY1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Fat-plasma cell Tabula Sapiens Gene-Cell Associations 1.0 -0.114324 BRD-K91279674 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.1562 ETFDH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.17119 PCGF4-22325352-293T-REX-HUMAN ChEA Transcription Factor Targets 2022 1.0 null HSPA8 Pathway Commons Protein-Protein Interactions 1.0 null UFSP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.0164 sodium arsenite CTD Gene-Chemical Interactions 1.0 null Lung adenocarcinoma_LUAD_TCGA-44-7660-01A-11R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KD DepMap CRISPR Gene Dependency 1.0 3.65573 anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.67429 SW 948 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22468 BRD-K65933652 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.17361 CRCGN015_MCF10A_48H:G18 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.0784 neoplasm of the oral cavity HPO Gene-Disease Associations 1.0 null hippocampus (hippocampal formation)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.1749 TMOD3 Pathway Commons Protein-Protein Interactions 1.0 null Acute leukemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.081 496100320_PCx_no dementia_TBI_79_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.11253 GSE48812_3_v_5_sulforaphane_human RummaGEO Drug Perturbation Signatures 1.0 null PAX5 ENCODE Transcription Factor Targets 1.0 null SK-HEP-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null single-multicellular organism process GO Biological Process Annotations 2015 1.0 null rubinstein-taybi syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.609276 Bone marrow cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.26 Carcinogenesis DisGeNET Gene-Phenotype Associations 1.0 null striatum_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.941676 BRD-K35792251 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.12998 STAMBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.08611 PMC4848008__F2 PFOCR Pathway Figure Associations 2024 1.0 null COLO677 CCLE Cell Line Gene Expression Profiles 1.0 1.48568 DOV13 COSMIC Cell Line Gene Mutation Profiles 1.0 null ETS2 MotifMap Predicted Transcription Factor Targets 1.0 null regulation of smoothened signaling pathway GO Biological Process Annotations 2015 1.0 null PMC12486367-Supplementary_Data2.pdf-327-ZNF263_ZNF263 Rummagene Transcription Factor Associations 2026 1.0 null NCOA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.64832 ZNF384_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1171 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.31918 LTBR_INHIBITION - 2 Days_GDS2005_729_mouse_Lymph nodes (MG-430B) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null BRD-K27026825 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.68206 Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U9-06A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Li-Fraumeni syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.205 Tooth TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.903 GTEx Colon 20-29 vs 50-59 GTEx Tissue-Specific Aging Signatures 1.0 4.46474 BACH1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.16568 GTEX-WFG7-0726-SM-3GIKO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14989 Plexiform neurofibroma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.065 hedgehog receptor activity GO Molecular Function Annotations 2015 1.0 null 496100362_FWM_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.64774 POLR1E Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_epithelial cell of esophagus_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null IZ in posteror frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.08914 cleidocranial dysplasia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.544705 FAM32A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.06535 NALM19 CCLE Cell Line Gene Mutation Profiles 1.0 null MAP1B Pathway Commons Protein-Protein Interactions 1.0 null Nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.164 RNR2 Hub Proteins Protein-Protein Interactions 1.0 null cefamandole-3696 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null parietal lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.195956 Lung adenocarcinoma_LUAD_TCGA-91-6835-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null musculoskeletal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.059263 keratocyst TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.551695 PMC5807095__F3 PFOCR Pathway Figure Associations 2023 1.0 null foregut TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.247719 Medulloblastoma ClinVar Gene-Phenotype Associations 2025 1.0 null nbccs GeneRIF Biological Term Annotations 1.0 null Basal cell carcinoma ClinVar Gene-Phenotype Associations 2025 1.0 null Intine COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.685 Basal Cell Carcinoma DisGeNET Gene-Disease Associations 1.0 null Ovarian sex-cord stromal tumor DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.03 RL95-2 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.777 RUNX3 ENCODE Transcription Factor Targets 1.0 null CORL24 CCLE Cell Line Gene CNV Profiles 1.0 2.49991 H3K4me1_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null RAB6A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.26256 RPS3A Pathway Commons Protein-Protein Interactions 1.0 null brain stem TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.414293 RCOR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TBP_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormality of the respiratory system GWASdb SNP-Phenotype Associations 1.0 0.120386 GTEX-UTHO-3126-SM-3P5ZB GTEx Tissue Sample Gene Expression Profiles 1.0 0.992028 PMC8432043__F1 PFOCR Pathway Figure Associations 2024 1.0 null Perturb_2005_KO_Msi2_SRP201799 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.41286 CTCF_fibroblast of upper leg skin_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Vertebrate muscular system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 RAB3A_Mutation - D77G point mutation_GDS2483_697_mouse_Cortex GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Creb5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.2005 H3K4me3_fibroblast of upper leg skin_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GATA6-21074721-CACO-2-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Perturb_11862_KO_Yap_SRP186725 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -8.64235 GTEX-OHPN-0005-SM-2YUML GTEx Tissue Sample Gene Expression Profiles -1.0 -1.05366 496100593_TCx_no dementia_TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.20529 GTEX-RVPU-0008-SM-3NM8B GTEx Tissue Sample Gene Expression Profiles -1.0 -0.957085 Lung carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.385 Immune System Diseases CTD Gene-Disease Associations 1.0 1.03493 PMC10286347-12905_2023_2426_MOESM1_ESM.docx-0-POU5F1_POU5F1 Rummagene Transcription Factor Associations 2026 1.0 null HT-115 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-OIZI-0126-SM-3NB13 GTEx Tissue Sample Gene Expression Profiles 1.0 1.24785 Prostate adenocarcinoma_PRAD_TCGA-G9-7523-01A-11R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BFTC-905 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.81133 RPL22 Pathway Commons Protein-Protein Interactions 1.0 null Renal cell carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.044 OVCAR433 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11112 BRD-K85234739 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.35226 PMC6520398-41467_2019_10148_MOESM11_ESM.xls-FigS1a-TP53_TP53 Rummagene Transcription Factor Associations 2026 1.0 null abnormal erythrocyte morphology MGI Mouse Phenotype Associations 2023 1.0 null Tooth bud TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.141 placenta_6a HPA Tissue Sample Gene Expression Profiles -1.0 -2.79276 H3K4me1_Brain Germinal Matrix Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GSE98755,GSE98756_1_v_0_fbxl19_mouse RummaGEO Gene Perturbation Signatures -1.0 null SPIN1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-R55E-0126-SM-2TC5Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.17701 SOX10 MotifMap Predicted Transcription Factor Targets 1.0 null H3K4me3_fibroblast of upper leg skin_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null cataract HPO Gene-Disease Associations 1.0 null primary auditory cortex (core)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.80573 SCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.28308 coloboma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.837246 ZNF281 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 142.158 PMC6200785__F8 PFOCR Pathway Figure Associations 2024 1.0 null GSE213228_4_v_3_irak2_human RummaGEO Gene Perturbation Signatures -1.0 null Perturb_15687_KO_Pten_SRP095406 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 POTEKP Pathway Commons Protein-Protein Interactions 1.0 null Cleft lip DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.76 Weight Loss CTD Gene-Disease Associations 1.0 1.02077 Pharyngeal tooth TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.207 negative regulation of smoothened signaling pathway GO Biological Process Annotations 2025 1.0 null PMC8848980__F6 PFOCR Pathway Figure Associations 2024 1.0 null betonicine-4301 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null D-502MG GDSC Cell Line Gene Expression Profiles 1.0 2.12557 LUDLU1 CCLE Cell Line Gene CNV Profiles -1.0 -1.34178 Osteochondrodysplasia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.097 Odontoblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.894 BRD-K42008693 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.36375 GSE192663_3_v_5_acly_mouse RummaGEO Gene Perturbation Signatures 1.0 null Prostate adenocarcinoma_PRAD_TCGA-J9-A8CK-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K01237500 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00575 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H0-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PIK3C2A Pathway Commons Protein-Protein Interactions 1.0 null ARRB1 Hub Proteins Protein-Protein Interactions 1.0 null CRCGN012_HEPG2_24H:F21 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.2175 NCI-H2110 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.859485 PORCN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.02534 GSE200352_10_v_0_pparg_mouse RummaGEO Gene Perturbation Signatures -1.0 null AM-38 COSMIC Cell Line Gene Mutation Profiles 1.0 null Tinea capitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.22 Six4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.5824 acrocephalosyndactylia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.397098 H3K4me3_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-X88G-0004-SM-47JZ6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.24555 647-V GDSC Cell Line Gene Expression Profiles -1.0 -1.48 JNK_KO_GDS3001_531_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null NCIH1339 CCLE Cell Line Gene Mutation Profiles 1.0 null GSE196104,GSE196106_2_v_0_vsx2_mouse RummaGEO Gene Perturbation Signatures -1.0 null K2 COSMIC Cell Line Gene Mutation Profiles 1.0 null Jun JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.3518 Skin stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.325 U20S BioGPS Cell Line Gene Expression Profiles -1.0 -1.19709 molecular_function GO Molecular Function Annotations 2015 1.0 null aplasia/hypoplasia of the phalanges of the thumb HPO Gene-Disease Associations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7469-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K32516224 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.40951 dorsolateral prefrontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.16227 abnormal dermal layer morphology MPO Gene-Phenotype Associations 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QH-01A-21R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SG in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.919589 GSE151494_1_v_9_nrp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null RPL7A Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null supernumerary ribs HPO Gene-Disease Associations 1.0 null MEL-HO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.876873 Skin tag DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.076 BRD-K61866431 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.37992 oculocutaneous albinism DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.370737 GSE168473_0_v_1_isoniazid_human RummaGEO Drug Perturbation Signatures 1.0 null outer SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.04013 ARRB1 Pathway Commons Protein-Protein Interactions 1.0 null SAS acetyltransferase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.64 Pollen wall COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.71 GTEX-N7MT-0007-SM-3GACQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.930983 cotinine-4650 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null HCC2218 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.637584 inner CP in posteror frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.0185 Becker GDSC Cell Line Gene Expression Profiles -1.0 -1.7534 KMS-27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.50116 Sarcoma_SARC_TCGA-PC-A5DN-01A-12R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Spindle cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.673 GSE110248_1_v_6_romidepsin_human RummaGEO Drug Perturbation Signatures 1.0 null REST_neural cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE242290_1_v_11_glutathione_human RummaGEO Drug Perturbation Signatures -1.0 null primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.402 BRD-K09689420 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.34779 Neck TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 CCN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.1238 liver HPA Tissue Protein Expression Profiles -1.0 -0.897918 GTEX-XPT6-0008-SM-4B64Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03735 NFIC ENCODE Transcription Factor Targets 1.0 null BRD-K18313650 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.68861 BRD-K29728947 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.33071 PMC3715061__F1 PFOCR Pathway Figure Associations 2023 1.0 null germ cell and embryonal cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.00035 RAB1A Pathway Commons Protein-Protein Interactions 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A86F-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SCL-21571218-MEGAKARYOCYTES-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-NPJ7-1726-SM-2YUNA GTEx Tissue Sample Gene Expression Profiles 1.0 0.977371 H3K27me3_CD4+ CD25- CD45RA+ Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Muscle TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Keratocyst TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.772 Salivary_Gland-duct epithelial cell Tabula Sapiens Gene-Cell Associations 1.0 2.36162 mRNA_KLF4_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null naphazoline-6604 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-XUYS-0002-SM-47JXL GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04058 hsa-miR-4254 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 BRD-A08778300 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.01885 HEC59 CCLE Cell Line Gene Mutation Profiles 1.0 null posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.57803 respiratory system cancer GWASdb SNP-Disease Associations 1.0 0.289142 infratentorial cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.117355 OSBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.40497 negative regulation of cellular process GO Biological Process Annotations 2015 1.0 null GSE230263,GSE230265_5_v_1_runx1_human RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_retinal pigment epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-R55C-1426-SM-48FED GTEx Tissue Sample Gene Expression Profiles 1.0 1.25873 hematopoietic system phenotype MPO Gene-Phenotype Associations 1.0 null H3K4me2_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC3691204__F1 PFOCR Pathway Figure Associations 2023 1.0 null FADU COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-X3Y1-0006-SM-3P5ZG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.34439 SUM 1315M02 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.62731 primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.6031 ventrolateral prefrontal cortex_35 pcw_F_12295 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.47758 H3K4me3_BE2C_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CDCA8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38089 PC-14 COSMIC Cell Line Gene Mutation Profiles 1.0 null canadine-4020 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GSE118617,GSE118619_0_v_1_foxp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null uterine fibroid DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.297291 LRP4 Pathway Commons Protein-Protein Interactions 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5100-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_A549_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null SPAG4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.46281 Reactive cutaneous fibrous lesion DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.076 PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_21_KLF4 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-WL46-3026-SM-3LK7Z GTEx Tissue Sample Gene Expression Profiles 1.0 1.22648 TMEM120A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01359 H3K4me1_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null extramedullary hematopoiesis MGI Mouse Phenotype Associations 2023 1.0 null GSE232631_0_v_3_brca2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Inner ear vestibulum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.045 H3K4me3_cardiac fibroblast_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null SRF ENCODE Transcription Factor Targets 1.0 null NFYA-21822215-K562-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-XBEW-0002-SM-4AT5O GTEx Tissue Sample Gene Expression Profiles -1.0 -1.73615 HEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.978045 H3K4me2_Muscle Satellite Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Specific developmental disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.227 Prostate adenocarcinoma_PRAD_TCGA-EJ-A46G-01A-31R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Rectum adenocarcinoma_READ_TCGA-F5-6864-01A-11R-1928-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NAA10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.06283 transverse gyri, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.31533 membrane part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.043413 15845616-SuppTable3 GeneSigDB Published Gene Signatures 1.0 null Brain disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.122 FEZ2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.73834 tail of caudate Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.88801 vitamin c_homo sapiens_gpl570_gse11919 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Macrostomia DisGeNET Gene-Disease Associations 1.0 null Orofacial cleft DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.769 VZ in dorsomedial extrastriate cortex (V2) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.0315 Cancer stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.68 TSACC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2851 Sarcoma_SARC_TCGA-LI-A67I-01A-31R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CRCGN015_HEPG2_48H:G16 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.0173 neural crest TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.224398 disease of metabolism DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.042477 ZRANB2 Pathway Commons Protein-Protein Interactions 1.0 null ventrolateral prefrontal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.33179 integral component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 abnormality of the nasal bridge HPO Gene-Disease Associations 1.0 null disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.044432 abnormal enchondral ossification HPO Gene-Disease Associations 1.0 null HCC2935 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.98712 Sprengel Deformity DisGeNET Gene-Disease Associations 1.0 null Notochord TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.003 NCI-H520 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 3.19301 GSE143994_0_v_1_ythdf1_human RummaGEO Gene Perturbation Signatures 1.0 null fallopian tube HPA Tissue Protein Expression Profiles 1.0 0.96344 Acute Myeloid Leukemia_LAML_TCGA-AB-2920-03B-01T-0760-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Panicle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.843 GTEX-S3XE-0426-SM-3K2AC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04733 TROVE2 Hub Proteins Protein-Protein Interactions 1.0 null PMC5316868__F3 PFOCR Pathway Figure Associations 2023 1.0 null TMEM19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.2618 H3K4me2_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null short ribs HPO Gene-Disease Associations 1.0 null SIN3A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.772759 BRD-K11504463 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.38717 GSE125219,GSE125221_4_v_2_arid1a_human RummaGEO Gene Perturbation Signatures -1.0 null SNAPC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.2409 PDLIM5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.00918 GTEX-RNOR-0005-SM-2TF4Z GTEx Tissue Sample Gene Expression Profiles -1.0 -0.962474 PMC5817105-thnov08p0972s2.xls-SIX3-GeneName_SIX3 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me1_CD8 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null UMUC3 CCLE Cell Line Gene Mutation Profiles 1.0 null DCAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.2987 PK-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.06178 abnormality of skeletal morphology HPO Gene-Disease Associations 1.0 null Neural ectoderm TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.858 temporal pole, left, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.989892 UM-UC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07599 ACTA1 Pathway Commons Protein-Protein Interactions 1.0 null PPP2R5D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.31184 496100317_FWM_no dementia_no TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.12555 NFRKB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44868 mRNA_ASCL1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null RCOR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OXRK-0006-SM-2HML1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.34874 EFE184 CCLE Cell Line Gene Expression Profiles 1.0 2.3327 KLE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.67234 BRD-K01237277 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.07258 Hedgehog 'on' state Reactome Pathways 2024 1.0 null BRD-K28623804 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.87395 GTEX-TKQ1-0006-SM-33HBI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.886918 GTEX-WWYW-3026-SM-3NB36 GTEx Tissue Sample Gene Expression Profiles 1.0 0.879904 bone development disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.269753 GTEX-U3ZM-1626-SM-4DXSK GTEx Tissue Sample Gene Expression Profiles 1.0 1.31785 GTEX-PSDG-0008-SM-48TE5 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.1122 PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-Fay_Heat_LPStoThermoneutral_LPS-Gene_Symbol_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me1_erythroblast_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-U3ZN-0006-SM-3DB7Y GTEx Tissue Sample Gene Expression Profiles -1.0 -0.934728 regulation of cell growth GO Biological Process Annotations 2025 1.0 null GTEX-R55C-0005-SM-3GAE9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.90636 CNGA3 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K35324337 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.53026 NCI-H1436 COSMIC Cell Line Gene Mutation Profiles 1.0 null BRD-K99302735 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07452 H3K4me2_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Basal cell carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.898 Small_Intestine Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -0.985725 Skin benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.22 EKVX CCLE Cell Line Gene CNV Profiles 1.0 2.3815 H3K4me3_Brain Mid Frontal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Skin disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.289 striatum_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.902532 CRCGN008_HEPG2_24H:M04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.0837 ATXN2L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.86719 BRD-K63987422 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.5895 Prenatal Injuries CTD Gene-Disease Associations 1.0 1.20196 MS751 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.44132 microphthalmia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.587444 GJA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.33669 GTEX-OHPL-0006-SM-3MJHB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.47359 mesenchyme TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.925051 H3K4me3_CD19 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Holoprosencephaly DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.2 abnormality of brain morphology HPO Gene-Disease Associations 1.0 null PMC3383648__F1 PFOCR Pathway Figure Associations 2024 1.0 null abnormality of the mandible HPO Gene-Disease Associations 1.0 null WDR73 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.26411 BRD-K16943897 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.20512 CRCGN011_HEPG2_24H:H15 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.5259 H3K4me3_Brain Cingulate Gyrus Roadmap Epigenomics Histone Modification Site Profiles 1.0 null DNAJC8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.51474 CRCGN009_HEPG2_24H:E14 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.20543 epidermal hyperplasia MGI Mouse Phenotype Associations 2023 1.0 null neoplasm by anatomical site GWASdb SNP-Phenotype Associations 1.0 0.115013 Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.345 RD cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.788 embryonic stem feeder layer BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.23083 ZR751 CCLE Cell Line Gene CNV Profiles -1.0 -1.50096 H3K4me3_skeletal muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Anemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.002 epithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.560449 primary auditory cortex (core)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.08806 CP66-MEL COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-X4EP-0005-SM-3P5ZE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.63677 smooth muscle HPA Tissue Protein Expression Profiles -1.0 -2.29659 vacuole LOCATE Predicted Protein Localization Annotations 1.0 null IMR-32 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.69077 496100457_TCx_dementia_TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.01944 H3K4me1_Adult Liver Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE113106_3_v_4_dnm2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2904-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VIIB, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.78519 TUBA4A Pathway Commons Protein-Protein Interactions 1.0 null RCOR1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ERCC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.44698 GTEX-OHPK-0326-SM-2HMJO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.98427 ACACA Pathway Commons Protein-Protein Interactions 1.0 null disease GWASdb SNP-Disease Associations 1.0 0.035367 GSE133763_0_v_1_chd1_human RummaGEO Gene Perturbation Signatures -1.0 null Leukemia DisGeNET Gene-Disease Associations 1.0 null RPL6 Pathway Commons Protein-Protein Interactions 1.0 null GSE202434,GSE202438_15_v_1_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null Basal Cell Nevus Syndrome DisGeNET Gene-Disease Associations 1.0 null GTEX-U8XE-0005-SM-3DB8I GTEx Tissue Sample Gene Expression Profiles -1.0 -0.911822 cancer GWASdb SNP-Disease Associations 1.0 0.116145 head TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.773174 Cardiovascular system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.337 H3K4me3_fibroblast of lung_hg19_7 ENCODE Histone Modification Site Profiles 1.0 null Glioblastoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.546 CHP212 CCLE Cell Line Gene CNV Profiles -1.0 -2.43091 CTCF_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Peripheral nerve sheath neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.002 URM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.04559 WDR36 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8381 SARS-CoV MA15_Day1-PFU-10^4_None_GSE33266 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.94756 GSE237053_1_v_0_comt_human RummaGEO Gene Perturbation Signatures 1.0 null KTN1 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WRHU-0626-SM-3MJFI GTEx Tissue Sample Gene Expression Profiles 1.0 2.2081 GTEX-WFG8-0001-SM-4LVN8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16644 CHL1DM DepMap CRISPR Gene Dependency 1.0 2.89356 lateral tuberal nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.58628 U937 CCLE Cell Line Gene Expression Profiles 1.0 1.36654 spleen HPA Tissue Protein Expression Profiles -1.0 -1.50075 GTEX-N7MT-1226-SM-2D7W4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.961528 FOS::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.5306 ZNF721 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.67941 GTEX-WYVS-1626-SM-3NM9R GTEx Tissue Sample Gene Expression Profiles 1.0 0.854058 GSE256181_2_v_3_etv2_human RummaGEO Gene Perturbation Signatures 1.0 null paraterminal gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.0171 BRD-K54593730 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.83059 RERFLCAD1 CCLE Cell Line Gene Expression Profiles -1.0 -2.06436 Breast disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.685 H3K27ac_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NOLC1 Pathway Commons Protein-Protein Interactions 1.0 null Floret TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.257 abnormal internal genitalia HPO Gene-Disease Associations 1.0 null GTEX-RNOR-0926-SM-2TF56 GTEx Tissue Sample Gene Expression Profiles 1.0 1.07528 BRD-K96547094 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.77311 RRP15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32051 GTEX-QESD-0526-SM-2I5G5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.843991 NANOG-16518401-CHIP-PET-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Dental lamina TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.493 H3K4me1_mononuclear cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF-27219007-CHIP-SEQ-ERYTHROID-HUMAN ChEA Transcription Factor Targets 2022 1.0 null inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.878144 H3K4me3_fibroblast of villous mesenchyme_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-T2IS-2226-SM-4DM65 GTEx Tissue Sample Gene Expression Profiles 1.0 1.01891 abnormality of joint mobility HPO Gene-Disease Associations 1.0 null BRD-K29636267 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.41132 VIIIA Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.02733 SDC3 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-XLM4-0005-SM-4AT4P GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16445 Thyroid gland follicular carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.471 BRD-A47166394 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -5.03051 TBX15 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.0486 abnormal immune system organ morphology MPO Gene-Phenotype Associations 1.0 null GTEX-QDVN-0006-SM-48U1R GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59299 Class Iii Malocclusion DisGeNET Gene-Disease Associations 1.0 null CHD4_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE162739_7_v_1_bap1_mouse RummaGEO Gene Perturbation Signatures 1.0 null FOXO1_KO_GSE40655_481_mouse_T reg GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GSE149880_2_v_3_tamoxifen_mouse RummaGEO Drug Perturbation Signatures 1.0 null LB647-SCLC GDSC Cell Line Gene Expression Profiles 1.0 1.68846 Prostate cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.47 PMC3084000__F1 PFOCR Pathway Figure Associations 2024 1.0 null Multiple endocrine neoplasia type 2A DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.497 NB7 DepMap CRISPR Gene Dependency 1.0 4.21074 CRCGN016_MCF10A.WT.HP_24H:G10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.42704 H3K4me2_myocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7611-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF382 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.5844 CTTN Pathway Commons Protein-Protein Interactions 1.0 null increased neutrophil cell number MGI Mouse Phenotype Associations 2023 1.0 null GSE248858_5_v_7_tcpobop_mouse RummaGEO Drug Perturbation Signatures 1.0 null H3K4me2_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-YL-A8SF-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H2AFZ_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OCUM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.7986 GSE200352_10_v_6_pparg_mouse RummaGEO Gene Perturbation Signatures -1.0 null Hemangioma of intra-abdominal structure DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.085 STRIP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.03407 RPL3 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K07414059 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.34228 dorsomedial hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.838973 Genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.926 HNRNPA1 Pathway Commons Protein-Protein Interactions 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A76K-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K48113109 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.36143 TGOLN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.58268 normal phenotype MPO Gene-Phenotype Associations 1.0 null COLO-704 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.971198 Fetal Death CTD Gene-Disease Associations 1.0 1.34547 adductor TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.350372 MYO1C Pathway Commons Protein-Protein Interactions 1.0 null GTEX-TSE9-0005-SM-4DXUF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.72612 Tonsil TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 abnormality of the cerebrospinal fluid HPO Gene-Disease Associations 1.0 null OVISE CCLE Cell Line Gene Mutation Profiles 1.0 null H3K27ac_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XQ8I-0726-SM-4BOPU GTEx Tissue Sample Gene Expression Profiles 1.0 0.891553 COLO 849 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.91227 NANOG-16518401-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null TE-11 GDSC Cell Line Gene Expression Profiles 1.0 1.66929 III, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.969422 X, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.40007 H3K4me1_MEL cell line_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-A74J-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-A96537953 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03508 Vdr JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.4031 PARP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.21377 MELJUSO CCLE Cell Line Gene Expression Profiles -1.0 -1.58259 HEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.80813 CRCGN015_HEPG2_48H:F04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.01083 inherited metabolic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.043837 Autosomal dominant disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.847 cancer GAD High Level Gene-Disease Associations 1.0 0.295739 abnormality of the sternum HPO Gene-Disease Associations 1.0 null H3K4me1_Neurosphere Cultured Cells Cortex Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null COLO 829 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.4227 SNRNP25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33348 HMGN3 ENCODE Transcription Factor Targets 1.0 null negative regulation of smoothened signaling pathway GO Biological Process Annotations 2023 1.0 null Hallux TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.507 GTEX-XAJ8-1326-SM-47JYT GTEx Tissue Sample Gene Expression Profiles 1.0 1.29218 primary motor cortex (area M1, area 4)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.82218 Lung adenocarcinoma_LUAD_TCGA-55-8512-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_mononuclear cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TRIM33 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35081 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4974-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE162276_4_v_0_rosiglitazone_mouse RummaGEO Drug Perturbation Signatures 1.0 null RFX5_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TE-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null stomodeum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.851686 8MGBA CCLE Cell Line Gene CNV Profiles 1.0 1.57537 anatomical structure development GO Biological Process Annotations 2015 1.0 null seminiferous tubule TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.33156 buflomedil-4258 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null PMC12634441-41375_2025_2771_MOESM8_ESM.xlsx-ATACseq-Table_S3_Bulk_ATAC-seq_GATA2_vs_control_Only_p-adj_0_05_GATA2 Rummagene Transcription Factor Associations 2026 1.0 null GSE198165,GSE198166_8_v_4_zfp266_mouse RummaGEO Gene Perturbation Signatures 1.0 null Skeletal system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 hek293 HPA Cell Line Gene Expression Profiles 1.0 0.925956 SP in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.976571 REEP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42666 Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUP-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null signal transduction GO Biological Process Annotations 2015 1.0 null DETROIT 562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22468 alveolar bone TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.669657 short metacarpal HPO Gene-Disease Associations 1.0 null GSE180200,GSE180201_5_v_0_qpctl_mouse RummaGEO Gene Perturbation Signatures -1.0 null SMAD1-18555785-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null BRD-K53619784 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.1157 PLK4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00114 leukemia cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.069011 sprengel anomaly HPO Gene-Disease Associations 1.0 null BRD-K72770355 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.19723 Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PSME3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49898 H3K4me3_mammary epithelial cell_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-3613-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.632343 negative regulation of signal transduction GO Biological Process Annotations 2015 1.0 null intrinsic component of plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.130154 CRCGN011_HEPG2_24H:I24 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.22295 membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 SW 403 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.28308 STK38 Pathway Commons Protein-Protein Interactions 1.0 null GSE203308_7_v_10_brf1_mouse RummaGEO Gene Perturbation Signatures -1.0 null HNRNPM Pathway Commons Protein-Protein Interactions 1.0 null HSPA9 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-WHPG-0006-SM-3NMBV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.36609 BRD-K07035171 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.14521 GSE238018_3_v_4_mxra8_human RummaGEO Gene Perturbation Signatures 1.0 null CHGB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34995 EZH2_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NFE2L3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.05207 SIN3A ENCODE Transcription Factor Targets 1.0 null GTEX-XBED-2026-SM-4AT5D GTEx Tissue Sample Gene Expression Profiles 1.0 0.9874 GTEX-NPJ8-2626-SM-2D7W2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.26761 H3K4me1_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null abnormality of female internal genitalia HPO Gene-Disease Associations 1.0 null hESC Derived CD184+ Endoderm Cultured Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 1.22405 Corpus luteum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.011 GTEX-SUCS-0008-SM-4DM53 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.33645 GSE126127_5_v_4_prmt1_mouse RummaGEO Gene Perturbation Signatures 1.0 null dorsolateral prefrontal cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.1262 Perturb_1295_KO_Trp53_SRP298760 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.6527 Female reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.6 GTEX-X4XX-2926-SM-3NMB1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.23985 BRD-K28885073 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.58189 BRD-K54042694 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.42391 mediodorsal nucleus of thalamus_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.25943 NIPA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30443 H3K4me3_Rectal Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null hsa-miR-4268 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 PC14 CCLE Cell Line Gene Mutation Profiles 1.0 null H3K9ac_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Jaw TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.129 Ciliary base COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.058 POLE2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62631 BRD-K91500340 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.66738 GSE232631_5_v_1_brca2_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_Caco-2_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null ZNF454 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 130.055 Uterine cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.202 TOV112D DepMap CRISPR Gene Dependency 1.0 2.31753 CRCGN009_HEPG2_24H:D11 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 7.7615 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7059-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_ES-Bruce4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K04546974 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.7736 BRD-K76611906 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.64841 Nuclear inclusion body COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.549 H3K4me1_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-4774-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 BRD-K06529600 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.5039 MRPL43 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.95928 BRD-K70854630 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.423 GTEX-SSA3-0226-SM-32QPN GTEx Tissue Sample Gene Expression Profiles 1.0 1.02727 GSE122215,GSE122217_0_v_4_peg10_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me1_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null abnormality of the hard palate HPO Gene-Disease Associations 1.0 null PKN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.13751 mRNA_SOX9_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null sirolimus_mus musculus_gpl1261_gse5332 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-SNMC-0126-SM-2XCFO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.38909 Lung adenocarcinoma_LUAD_TCGA-78-8640-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null sno(s)RNA-containing ribonucleoprotein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.961 GSK3B_KD_GDS4305_181_human_MOLM-14 myeloid leukemia cell line GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null H3K4me3_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SCLY ChEA Transcription Factor Targets 1.0 null Kidney Chromophobe_KICH_TCGA-KN-8422-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TBX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.8357 H3K4me3_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Chronic myeloid leukemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.129 Prostate adenocarcinoma_PRAD_TCGA-HC-A4ZV-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S4Z8-1926-SM-3K2AR GTEx Tissue Sample Gene Expression Profiles 1.0 0.951139 Lung disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.611 NCI-H1882 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.08037 u26684 HPA Cell Line Gene Expression Profiles 1.0 1.63135 neoplasm of the heart HPO Gene-Disease Associations 1.0 null Ceratobranchial TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.043 NPHP complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.649 PHF8 ENCODE Transcription Factor Targets 1.0 null GSE161295_4_v_3_cdk8_mouse RummaGEO Gene Perturbation Signatures -1.0 null CRCGN011_HEPG2_24H:F03 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.3463 Hamartoma DisGeNET Gene-Phenotype Associations 1.0 null 17617570-Table3 GeneSigDB Published Gene Signatures 1.0 null GSE242199_6_v_5_ntrk2_human RummaGEO Gene Perturbation Signatures -1.0 null GSE48812_11_v_1_sulforaphane_human RummaGEO Drug Perturbation Signatures 1.0 null large intestine cancer GWASdb SNP-Disease Associations 1.0 0.447588 esophagus HPA Tissue Protein Expression Profiles 1.0 0.96344 Musculoskeletal system benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.869 HNRNPK Pathway Commons Protein-Protein Interactions 1.0 null Pharyngeal cavity TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.51 BRD-K60595964 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05136 SNU601 CCLE Cell Line Gene CNV Profiles -1.0 -1.8755 H3K4me3_A549_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null TAF1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC11143203-41422_2024_945_MOESM13_ESM.pdf-37-JUNB_JUNB Rummagene Transcription Factor Associations 2026 1.0 null glaucoma HPO Gene-Disease Associations 1.0 null tooth TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.635976 D283MED DepMap CRISPR Gene Dependency 1.0 2.53334 GTEX-WOFM-0005-SM-3MJF3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12695 GTEX-VJWN-0005-SM-3GIKF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.93562 BRD-K65875972 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.52573 Perturb_5814_KO_U2af1_SRP266807 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.36329 GTEX-OHPM-0008-SM-4E3IP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11856 GSE95077_1_v_4_amiloride_human RummaGEO Drug Perturbation Signatures 1.0 null POU5F1-18358816-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null testis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.544946 Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A3JM-01A-12R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K00920341 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.71855 mesenchymal cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.525166 GSE198165,GSE198166_6_v_3_zfp266_mouse RummaGEO Gene Perturbation Signatures -1.0 null NABP1 Hub Proteins Protein-Protein Interactions 1.0 null DHH Pathway Commons Protein-Protein Interactions 1.0 null PMC8166871__F7 PFOCR Pathway Figure Associations 2024 1.0 null Cleft Lip DisGeNET Gene-Disease Associations 1.0 null ectopic calcification HPO Gene-Disease Associations 1.0 null Digestive gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 basal GeneRIF Biological Term Annotations 1.0 null arcuate nucleus of medulla, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.13175 Primary enamel knot TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.721 GSE150072,GSE169209_6_v_9_qser1_human RummaGEO Gene Perturbation Signatures -1.0 null BRD-K28746174 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.1665 NCIH2029 CCLE Cell Line Gene CNV Profiles 1.0 2.2085 SARC9371 COSMIC Cell Line Gene Mutation Profiles 1.0 null HOXD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.9189 VIIIB, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.24139 chronic fatigue syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.199681 Pancreatic Carcinoma DisGeNET Gene-Disease Associations 1.0 null GTEX-T2YK-0008-SM-4DM6M GTEx Tissue Sample Gene Expression Profiles -1.0 -0.976803 medulloblastoma HPO Gene-Disease Associations 1.0 null cerebellar cortex_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.14456 BRD-A22502911 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.1406 GTEX-S33H-2326-SM-2XCB3 GTEx Tissue Sample Gene Expression Profiles 1.0 2.45102 GATB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10869 GTEX-RU72-3126-SM-46MUB GTEx Tissue Sample Gene Expression Profiles 1.0 0.976435 HS 936.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.925022 MACF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.86684 central nuclear group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.84714 GTEX-OHPM-2126-SM-3LK75 GTEx Tissue Sample Gene Expression Profiles 1.0 1.20346 Ameloblastoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.529 skeletal system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.310421 HCC366 CCLE Cell Line Gene Mutation Profiles 1.0 null abnormality of the lung GWASdb SNP-Phenotype Associations 1.0 0.152023 BRD-K97733472 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.86266 kidney HPA Tissue Gene Expression Profiles -1.0 -0.833443 SUM52PE Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.672392 TP53INP2_OE_GDS5054_276_mouse_SKM-Tg - Skeletal muscle GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Alimentary canal TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Nkx2-1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.7708 Perturb_5057_OE_Mir344_SRP161512 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 Hair follicle inner root sheath TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.225 PFKFB3 Pathway Commons Protein-Protein Interactions 1.0 null MEWO CCLE Cell Line Gene Mutation Profiles 1.0 null abnormality of the metacarpal bones HPO Gene-Disease Associations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-VN-A88I-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SIN3A_Panc1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormality of the chin HPO Gene-Disease Associations 1.0 null GSE200352_11_v_6_pparg_mouse RummaGEO Gene Perturbation Signatures -1.0 null Perturb_15875_KO_Atoh1_SRP002802 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -8.54758 GTEX-T5JC-0008-SM-4DM6A GTEx Tissue Sample Gene Expression Profiles -1.0 -1.06349 inner dental epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.22024 Neuromast TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.729 Basal cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.787 Neural crest TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.701 COR-L47 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.05206 EIF2B2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74606 ChIP_SMAD1_18555785 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GSE157282_0_v_1_doxorubicin_human RummaGEO Drug Perturbation Signatures 1.0 null fenbendazole-4542 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null tanespimycin-5919 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Ovary epithelial cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.08 Telomerase holoenzyme complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.639 hippocampus (hippocampal formation)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.965334 brain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.370496 GSE242290_3_v_2_glutathione_human RummaGEO Drug Perturbation Signatures -1.0 null DHX8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5117 H3K27me3_cardiac mesoderm_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-NFK9-0426-SM-2YUNK GTEx Tissue Sample Gene Expression Profiles 1.0 0.84872 GTEX-S7PM-0006-SM-3NM8C GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00866 tooth germ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.783972 aplasia/hypoplasia of fingers HPO Gene-Disease Associations 1.0 null RANBP10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.04076 Methionine CTD Gene-Chemical Interactions 1.0 null PMC10789969-crt-2023-577-Supplementary-Table-S2.pdf-22-PPARD_PPARD Rummagene Transcription Factor Associations 2026 1.0 null CRCGN008_HEPG2_24H:C23 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.5117 nerve GTEx Tissue Gene Expression Profiles 1.0 1.32203 syndrome GeneRIF Biological Term Annotations 1.0 null polydactyly HPO Gene-Disease Associations 1.0 null H3K4me1_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TP53INP2_OE_GDS5054_387_mouse_muscle GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null basal cell carcinoma HPO Gene-Disease Associations 1.0 null abnormal skin adnexa morphology MPO Gene-Phenotype Associations 1.0 null negative regulation of biological process GO Biological Process Annotations 2015 1.0 null GTEX-X8HC-2726-SM-46MUA GTEx Tissue Sample Gene Expression Profiles 1.0 1.04365 variable expressivity HPO Gene-Disease Associations 1.0 null Cleft Lip HuGE Navigator Gene-Phenotype Associations 1.0 null POLR2A_HeLa-S3_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XLM4-3126-SM-4AT6M GTEx Tissue Sample Gene Expression Profiles 1.0 0.840589 GTEX-T2IS-2026-SM-4DM6W GTEx Tissue Sample Gene Expression Profiles 1.0 1.62136 496100622_HIP_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.03687 Milium Cyst DisGeNET Gene-Disease Associations 1.0 null abnormal erythrocyte morphology MPO Gene-Phenotype Associations 1.0 null MAX_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null cis-Golgi network COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.583 cellular bud tip COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.848828 Signaling by GPCR Reactome Pathways 2024 1.0 null Irregular Ossification Of Hand Bones DisGeNET Gene-Phenotype Associations 1.0 null lateral parabrachial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.06586 striatum_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.863561 GTEX-RU72-2226-SM-46MUE GTEx Tissue Sample Gene Expression Profiles 1.0 0.977683 anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.03867 testicular neoplasm GWASdb SNP-Phenotype Associations 1.0 0.638004 Hydrolethalus syndrome 2 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.114 H3K4me1_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null KMH2 CCLE Cell Line Gene Expression Profiles 1.0 1.94725 HCC1576 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.25578 NCI-H2052 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07599 cause GeneRIF Biological Term Annotations 1.0 null GSE213048_1_v_2_irf3_mouse RummaGEO Gene Perturbation Signatures 1.0 null Skeletal muscle cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.984 alopecia MGI Mouse Phenotype Associations 2023 1.0 null H3K4me3_cardiac mesoderm_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null ZYX Pathway Commons Protein-Protein Interactions 1.0 null Liver BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.04425 neural plate TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.191782 BRD-K36940835 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.42799 BRD-K96154586 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.16076 Angioblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.614 BRD-K63270352 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.60213 Ovarian disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.515 abnormality of the sella turcica HPO Gene-Disease Associations 1.0 null GSE190947_2_v_0_xbp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null intravenous leiomyomatosis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.877786 spinal dysraphism HPO Gene-Disease Associations 1.0 null LN18 BioGPS Cell Line Gene Expression Profiles 1.0 1.34791 Brain Lower Grade Glioma_LGG_TCGA-HT-A617-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-RN64-0626-SM-2TC5V GTEx Tissue Sample Gene Expression Profiles 1.0 0.884936 mouth TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.589234 GSE159678_4_v_3_chloroquine_human RummaGEO Drug Perturbation Signatures -1.0 null Gata3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.6951 TOPBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.45249 clopamide-5402 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null C3A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.898049 Childhood Medulloblastoma DisGeNET Gene-Disease Associations 1.0 null GTEX-QCQG-2026-SM-2S1PH GTEx Tissue Sample Gene Expression Profiles 1.0 0.984017 PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-BrtoFay_Thermoneutral_LPS-Gene_Symbol_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null CTBP2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-44-6148-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K32520360 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.08809 Desmoplastic Medulloblastoma DisGeNET Gene-Disease Associations 1.0 null GSE169571_0_v_1_dexamethasone_mouse RummaGEO Drug Perturbation Signatures 1.0 null Adenoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.405 BRD-K64111129 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.31901 SW626 COSMIC Cell Line Gene Mutation Profiles 1.0 null epidermal stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.457987 inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.55902 H3K4me3_fibroblast of the aortic adventitia_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-UPIC-0005-SM-3GACV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.27909 Autophagosome lumen COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.502 KLF14 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 99.0058 TTN Pathway Commons Protein-Protein Interactions 1.0 null PMC8247090__F4 PFOCR Pathway Figure Associations 2024 1.0 null COX5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.04344 GSE248045,GSE248046_4_v_1_runx1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE181517_2_v_1_doxorubicin_human RummaGEO Drug Perturbation Signatures 1.0 null ISHIKAWA(HERAKLIO)02ER- COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC6668073__F4 PFOCR Pathway Figure Associations 2023 1.0 null HTh-74 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.583 UMRC6 CCLE Cell Line Gene Expression Profiles 1.0 1.59398 NCI-H847 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.28564 schwann cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.459532 Gorlin syndrome ClinVar Gene-Phenotype Associations 1.0 null increased fasting circulating glucose level IMPC Knockout Mouse Phenotypes 1.0 null Perturb_17686_OE_HSD17B1_SRP366068 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -6.25767 CTCF_fibroblast of gingiva_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hedgehog receptor activity GO Molecular Function Annotations 2023 1.0 null NCI-H1770 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.01506 Connective tissue benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.923 Bladder Urothelial Carcinoma_BLCA_TCGA-SY-A9G0-01A-12R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sarcoma_SARC_TCGA-MO-A47P-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_10885_KD_Mafg_SRP165897 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 8.862 POLR2A_olfactory bulb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null viscus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052488 H3K4me3_SK-N-MC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A49A-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bifid Ribs DisGeNET Gene-Phenotype Associations 1.0 null CRCGN014_HEPG2_24H:I02 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.21709 NHLH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.53444 PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR Rummagene Transcription Factor Associations 2026 1.0 null BRD-K71155312 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.42934 PMC9010822__F4 PFOCR Pathway Figure Associations 2024 1.0 null Prostate disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.467 GSE161295_4_v_1_cdk8_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-OIZI-0005-SM-2XCED GTEx Tissue Sample Gene Expression Profiles -1.0 -1.06811 SCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.40186 BRD-K88960810 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.28402 abnormal coat/ hair morphology MPO Gene-Phenotype Associations 1.0 null regulation of response to stimulus GO Biological Process Annotations 2015 1.0 null layer IIIa of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.13609 thigh muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.09771 choroid plexus of the fourth ventricle Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.921828 abnormal bone structure HPO Gene-Disease Associations 1.0 null MAX ENCODE Transcription Factor Targets 1.0 null JURKAT COSMIC Cell Line Gene Mutation Profiles 1.0 null Monogenic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.021 Cardinal vein TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.04 GTEX-X5EB-0006-SM-46MV5 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.07304 Acute Myeloid Leukemia_LAML_TCGA-AB-2919-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE196699_2_v_6_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null HEC251 CCLE Cell Line Gene Mutation Profiles 1.0 null CRCGN008_HEPG2_24H:J03 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.5374 GSE125862_2_v_0_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null DNA ligase IV complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.602 intracellular part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.301425 Dok TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.567 RUNX1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA ChEA Transcription Factor Targets 2022 1.0 null Integument TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 HCC1319 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.960528 hsa-miR-342-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 BACH2 Pathway Commons Protein-Protein Interactions 1.0 null PIGT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.00316 Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Reactome Pathways 2014 1.0 null BRD-K76539747 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.45631 Forebrain TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 GSE178255_3_v_0_tlr4_mouse RummaGEO Gene Perturbation Signatures -1.0 null outer SZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.17564 clinical modifier HPO Gene-Disease Associations 1.0 null HDAC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SG in midlateral extrastriate cortex (area 19) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 3.31429 H3K4me3_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Micronuclei, Chromosome-Defective CTD Gene-Disease Associations 1.0 1.06698 Central nervous system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.359 Rhabdomyosarcoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.955 H3K4me3_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CHD1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OAW28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.36647 mediodorsal nucleus of thalamus_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.9476 Abnormality Of The Ribs DisGeNET Gene-Disease Associations 1.0 null PLAGL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 72.7952 HCC515 DepMap CRISPR Gene Dependency 1.0 3.97805 Nthy-ori 3-1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.605 GTEX-PSDG-0005-SM-3GADC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.29425 metencephalon TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.357802 GSE132694,GSE132717_0_v_2_meis1_human RummaGEO Gene Perturbation Signatures -1.0 null OVISE COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-R55F-1226-SM-2TF59 GTEx Tissue Sample Gene Expression Profiles 1.0 0.87193 MAX_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null vascular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052835 GSE180951_6_v_0_bleomycin_mouse RummaGEO Drug Perturbation Signatures 1.0 null hindbrain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.471151 PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-ensembl_AR Rummagene Transcription Factor Associations 2026 1.0 null GTEX-WEY5-0001-SM-3P61Z GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0362 537 MEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.98882 CRCGN008_HEPG2_24H:E10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.0444 GTEX-RTLS-2426-SM-46MUO GTEx Tissue Sample Gene Expression Profiles 1.0 0.877707 GSE190947_1_v_0_xbp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE196699_4_v_3_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null 15558013-FigureS1b GeneSigDB Published Gene Signatures 1.0 null KCTD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22125 TO175T CCLE Cell Line Gene Mutation Profiles 1.0 null TPM4 Pathway Commons Protein-Protein Interactions 1.0 null H3K9ac_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SF172 CCLE Cell Line Gene Expression Profiles 1.0 1.67729 H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE186654_1_v_3_tcpobop_mouse RummaGEO Drug Perturbation Signatures -1.0 null GTEX-NPJ8-0011-R11A-SM-2YUMS GTEx Tissue Sample Gene Expression Profiles 1.0 1.14585 bridged sella turcica HPO Gene-Disease Associations 1.0 null HCC1395 GDSC Cell Line Gene Expression Profiles -1.0 -2.635 hsa-miR-765 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 SUDHL10 DepMap CRISPR Gene Dependency 1.0 3.426 Carcinoma, Hepatocellular CTD Gene-Disease Associations 1.0 1.01739 Learning Disorders CTD Gene-Disease Associations 1.0 1.70014 H3K27ac_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null female reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.701489 BRD-K00909602 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.07442 secondary spermatocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.657866 hsa-miR-3619-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.131849 H3K27me3_cardiac mesoderm_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null Hedgehog Signaling Pathway(Homo sapiens) WikiPathways Pathways 2014 1.0 null Thyroid adenoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.562 PMC3889689-elife01439s001.xls-RFX2_rnaseq_chip_DirectDE_final-ENSG_ID_RFX2 Rummagene Transcription Factor Associations 2026 1.0 null LS1034 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.40915 Perturb_123_KD_Fto_SRP314220 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 5.91659 MYC_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null neurodevelopmental abnormality HPO Gene-Disease Associations 1.0 null G122 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05664 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MR-06A-11R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-RVPU-0005-SM-2TF6L GTEx Tissue Sample Gene Expression Profiles -1.0 -0.973893 DU 145 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.858562 GTEX-QLQW-1026-SM-447A9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.40514 H3K9ac_Peripheral Blood Mononuclear Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me1_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE162739_6_v_1_bap1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Lymphoma_burkitts(Raji) BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.32396 Acute myeloid leukemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.275 male reproductive organ cancer GWASdb SNP-Disease Associations 1.0 0.3805 H3K4me3_fibroblast of pulmonary artery_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PHF8_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OVSAHO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.39309 EZH2_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hydralazine-4746 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K57719270 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.02612 Basal cell carcinoma KEGG Pathways 2026 1.0 null negative regulation of smoothened signaling pathway GO Biological Process Annotations 2015 1.0 null SALL4 ChEA Transcription Factor Targets 1.0 null H3K9ac_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Xeroderma pigmentosum DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.544 BRD-K70618663 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.049 GTEX-S7SE-0326-SM-4AT5Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.65579 neoplasm of the respiratory system GWASdb SNP-Phenotype Associations 1.0 0.300263 H3K4me3_Brain Inferior Temporal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K27me3_spleen_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_11975_KO_Star_SRP302975 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.96789 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4703-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Oral epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.078 Hedgehog signaling pathway KEGG Pathways 2026 1.0 null GSE60837_0_v_3_bcl9_mouse RummaGEO Gene Perturbation Signatures -1.0 null IGROV-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.959217 NCI-H2087 GDSC Cell Line Gene Expression Profiles -1.0 -2.20075 GSE182680,GSE182683_5_v_11_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-X88G-0008-SM-47JWN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.973001 BRD-K70237115 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.13935 ARHGAP11A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78962 striatum_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.850657 hypohidrotic ectodermal dysplasia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.604591 ZNF749 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.17014 GTEX-X4XX-0011-R11A-SM-46MWQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.11331 RPS17 Pathway Commons Protein-Protein Interactions 1.0 null adult stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.360782 neoplasm by histology HPO Gene-Disease Associations 1.0 null H2BK20ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MAF::NFE2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.9523 PHF8_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BHT-101 GDSC Cell Line Gene Expression Profiles -1.0 -1.74002 Intellectual disability DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.214 H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2ME-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CRCGN016_MCF10A.TP53.M_24H:H10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.44805 BRD-K99028283 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.76508 Brain Lower Grade Glioma_LGG_TCGA-S9-A7R3-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K15739647 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.33598 single-organism process GO Biological Process Annotations 2015 1.0 null H3K4me3_H7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Pancreatic carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.378 PMC8567280-EMBR-22-e53014-s007.xlsx-Sheet1-Nearest_genes_to_BAZ2A-bound_C2-Enhancers_BAZ2A Rummagene Transcription Factor Associations 2026 1.0 null Mesothelioma_MESO_TCGA-SC-A6LM-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null membrane LOCATE Predicted Protein Localization Annotations 1.0 null TCF12_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RKO CCLE Cell Line Gene Mutation Profiles 1.0 null irregular ossification of hand bones HPO Gene-Disease Associations 1.0 null Cardiac Rhabdomyoma DisGeNET Gene-Disease Associations 1.0 null H3K4me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null reproductive organ benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.191097 GTEX-QMR6-0011-R8A-SM-32PKJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.829424 cellular_component GO Cellular Component Annotations 2015 1.0 null GTEX-POMQ-2026-SM-2S1OD GTEx Tissue Sample Gene Expression Profiles 1.0 1.18876 ZNF432 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01536 primary somatosensory cortex (area S1, areas 3,1,2)_11 yrs_F_12289 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.962002 primary auditory cortex (core)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.845828 neoplasm of the nervous system HPO Gene-Disease Associations 1.0 null AN3 CA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.26867 H3K4me3_CD4+ CD25- Th Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K70148902 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.10349 GTEX-QEG4-0126-SM-48TZE GTEx Tissue Sample Gene Expression Profiles 1.0 1.34722 EFM-192C Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16551 locus ceruleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.44919 Pancreatic cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.865 RCOR1 ENCODE Transcription Factor Targets 1.0 null PMC5831777__F3 PFOCR Pathway Figure Associations 2023 1.0 null neurofibromatosis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.303781 H3K4me3_foreskin fibroblast_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null TLE4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.72953 abnormality of the vertebral column HPO Gene-Disease Associations 1.0 null PMC8143797-elife-62857-fig3-data2.xlsx-DEgenes_SW872_CAMTA1_vs_subEV-Gene_CAMTA1 Rummagene Transcription Factor Associations 2026 1.0 null PMC9643473-Table1.xls-MAF_0_005-HGVS_gene_MAF Rummagene Transcription Factor Associations 2026 1.0 null Lymphatic system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.403 placenta_6c HPA Tissue Sample Gene Expression Profiles -1.0 -0.983837 PMC11438719-43032_2024_1653_MOESM4_ESM.xlsx-dNKall6orig_fdr01_FC_rank-dNK_MAF_1_MAF Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K83670600 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.00908 Urinary bladder cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.137 Ameloblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.43 cerebral lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.068075 BRD-K05699155 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00023 NEPRO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.1491 H2AFZ_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Centralspindlin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.504 PMC5316868__F3 PFOCR Pathway Figure Associations 2024 1.0 null H3K27me3_small intestine_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3322-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nrd1 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.573 short phalanx of finger HPO Gene-Disease Associations 1.0 null Ectoderm TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.941 rotenone-5920 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null congenital heart disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.100021 NCI-H1793 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.861373 Plasma membrane bounded cell projection cytoplasm COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.45 Mammary luminal epithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.734 GTEX-WZTO-2826-SM-3NM8P GTEx Tissue Sample Gene Expression Profiles 1.0 0.852478 Signal Transduction Reactome Pathways 2024 1.0 null Basal cell nevus syndrome ClinVar Gene-Phenotype Associations 2025 1.0 null GTEX-RU72-0011-R8A-SM-2TF61 GTEx Tissue Sample Gene Expression Profiles 1.0 0.883942 GSE138818_1_v_3_nanog_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-QLQ7-0005-SM-2S1QP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.25253 WASHC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.48855 alimentary canal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056238 Bladder Urothelial Carcinoma_BLCA_TCGA-K4-AAQO-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null theca folliculi TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.184523 TT2609C02 CCLE Cell Line Gene Mutation Profiles 1.0 null CALM1 Pathway Commons Protein-Protein Interactions 1.0 null Childhood Rhabdomyosarcoma DisGeNET Gene-Disease Associations 1.0 null transmembrane signaling receptor activity GO Molecular Function Annotations 2015 1.0 null molecular transducer activity GO Molecular Function Annotations 2015 1.0 null signaling receptor activity GO Molecular Function Annotations 2015 1.0 null testis_4a HPA Tissue Sample Gene Expression Profiles 1.0 1.47558 Embryonal rhabdomyosarcoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.266 Cilium COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.425 ALYREF Pathway Commons Protein-Protein Interactions 1.0 null PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_22_KLF4 Rummagene Transcription Factor Associations 2026 1.0 null VPS16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.09641 GTEX-S4P3-0006-SM-3K2AW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.986671 H3K4me1_CD4 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null neuroblastoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.067443 BRD-K95678449 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.24298 Cleft Palate HuGE Navigator Gene-Phenotype Associations 1.0 null ferulic-acid LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.08303 LSM7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80479 Congenital Fusion Of Ribs DisGeNET Gene-Disease Associations 1.0 null BCPAP CCLE Cell Line Gene CNV Profiles 1.0 1.34513 hsa-miR-4768-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 GTEX-P4PP-0005-SM-2HMKX GTEx Tissue Sample Gene Expression Profiles -1.0 -2.84643 abnormality of the meninges HPO Gene-Disease Associations 1.0 null H3K4me2_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC6723230__F2 PFOCR Pathway Figure Associations 2024 1.0 null H3K4me3_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CSN2 Pathway Commons Protein-Protein Interactions 1.0 null POLR2A_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intestinal cancer GWASdb SNP-Disease Associations 1.0 0.447588 Pharyngeal epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.918 RBPJ-21746931-IB4-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Long bone TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.086 WM1552C COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE137177_1_v_0_folic acid_mouse RummaGEO Drug Perturbation Signatures -1.0 null hsa-miR-521 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 BRD-K92241728 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.51343 BRD-K14763154 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15461 Mesothelioma_MESO_TCGA-MQ-A4LP-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100367_FWM_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.39933 posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.54816 nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.042206 H3K4me1_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PBX3 ENCODE Transcription Factor Targets 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XD-01A-22R-A239-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-SIU8-0008-SM-4BRUC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.869172 SOX2-21211035-LN229-GBM ChEA Transcription Factor Targets 2022 1.0 null proadifen-2707 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null OCI-AML5 COSMIC Cell Line Gene Mutation Profiles 1.0 null cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.770844 H2AFZ_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAF1_neural cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYL12B Pathway Commons Protein-Protein Interactions 1.0 null MDAMB175VII CCLE Cell Line Gene CNV Profiles -1.0 -1.61105 family GeneRIF Biological Term Annotations 1.0 null abnormal coat appearance MPO Gene-Phenotype Associations 1.0 null Malignant Neoplasm DisGeNET Gene-Disease Associations 1.0 null Musculoskeletal system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.804 GTEX-P78B-0005-SM-2I5GM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.76785 GTEX-SIU8-0326-SM-2XCDR GTEx Tissue Sample Gene Expression Profiles 1.0 2.85902 G protein-coupled receptor binding GO Molecular Function Annotations 2025 1.0 null skin cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.13712 primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.91979 lithocholic acid-4551 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-7821-01A-12R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null col10 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.503 Gastrointestinal system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.749 GTEX-RUSQ-2126-SM-47JXK GTEx Tissue Sample Gene Expression Profiles 1.0 1.05624 bendroflumethiazide-4315 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-SN8G-0006-SM-32PLD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.52748 Urinary system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.442 VIIB, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.21351 POLR2AphosphoS5_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RN64-2326-SM-48FDW GTEx Tissue Sample Gene Expression Profiles 1.0 1.62989 NKX6-2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.07312 BRD-K64299311 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.01188 NFYB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.923 Connective tissue disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.673 H3K4me1_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null BRD-K99530482 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.04469 spleen BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.46784 Lung bud TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.762 primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.936239 BRD-K64072266 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.77609 CCS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09899 non-Hodgkin lymphoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.244 SRSF8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.30495 GTEX-S4Q7-0006-SM-3K2AT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.23812 pancreas GTEx Tissue Gene Expression Profiles -1.0 -0.876869 pallister-hall syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.770844 H3K4me3_Colon Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null all GWASdb SNP-Phenotype Associations 1.0 0.032826 PMC12586484-41598_2025_22484_MOESM2_ESM.xlsx-Supplementary_Table_1-Supplementary_Table_1_DEGs_in_ATOH8-depleted_EVT_ATOH8 Rummagene Transcription Factor Associations 2026 1.0 null YWHAZ Pathway Commons Protein-Protein Interactions 1.0 null secalciferol LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.09829 H3K4me1_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null C80 DepMap CRISPR Gene Dependency 1.0 2.15311 GTEX-U8XE-0126-SM-4E3I3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.11429 rhabdomyoma HPO Gene-Disease Associations 1.0 null inferior colliculus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.867293 spanning component of membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.311478 Disease of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.241 iPS-20b Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.43028 HDAC1 ENCODE Transcription Factor Targets 1.0 null endomesoderm TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.435672 H3K4me3_K562_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null neoplasm of the central nervous system HPO Gene-Disease Associations 1.0 null BRD-K21466747 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.24494 vegetative cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.19943 RT-112 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.928115 GSE140092_0_v_1_socs3_mouse RummaGEO Gene Perturbation Signatures 1.0 null UMC-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.925067 primary auditory cortex (core)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.81391 rostral subdivision of medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.06099 Signaling by GPCR Reactome Pathways 2014 1.0 null Polydactyly DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.86 GTEX-VJYA-0005-SM-3P5ZD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0014 PUR1 MotifMap Predicted Transcription Factor Targets 1.0 null Anxiety Disorders CTD Gene-Disease Associations 1.0 1.20427 Dentin TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.676 BRD-K25876174 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.5192 hsa-miR-16 TargetScan Predicted Conserved microRNA Targets 1.0 0.062888 GTEX-WOFL-0006-SM-3TW8K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.36063 GTEX-Q2AG-3026-SM-48U1L GTEx Tissue Sample Gene Expression Profiles 1.0 1.3147 abnormal hemoglobin content MPO Gene-Phenotype Associations 1.0 null Retinal stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.22 brain cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.077155 GTEX-XLM4-0004-SM-4AT5I GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14188 C-33-A COSMIC Cell Line Gene Mutation Profiles 1.0 null CHAGOK1 CCLE Cell Line Gene CNV Profiles 1.0 1.80672 abnormality of the curvature of the vertebral column HPO Gene-Disease Associations 1.0 null primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.995076 GSE120413,GSE120447_0_v_5_bap1_mouse RummaGEO Gene Perturbation Signatures -1.0 null gastrointestinal system cancer GWASdb SNP-Disease Associations 1.0 0.136087 abnormality of the distal phalanx of finger HPO Gene-Disease Associations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TM-A84B-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XUZC-1026-SM-4BOPY GTEx Tissue Sample Gene Expression Profiles 1.0 1.33873 H3K4me1_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NFYA ENCODE Transcription Factor Targets 1.0 null CRCGN008_HEPG2_24H:I10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.26375 GTEX-Q2AG-2826-SM-2HMJQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.876606 hematopoietic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055526 H3K4me3_retinal pigment epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-O5YT-2126-SM-3MJGD GTEx Tissue Sample Gene Expression Profiles 1.0 1.65301 GSE182680,GSE182683_5_v_1_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null GSE128240_0_v_1_cyclophosphamide_mouse RummaGEO Drug Perturbation Signatures 1.0 null primary motor cortex (area M1, area 4)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.35348 Infratentorial cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.731 cartilage-hair hypoplasia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.928346 GSE148200_3_v_2_gemcitabine_human RummaGEO Drug Perturbation Signatures 1.0 null Trunk TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Medulloblastoma CTD Gene-Disease Associations 1.0 2.88009 GTEX-Q2AG-0826-SM-2HMKF GTEx Tissue Sample Gene Expression Profiles 1.0 0.909254 WDFY1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.4599 Tumor Progression DisGeNET Gene-Phenotype Associations 1.0 null hsa-miR-371b-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 BRD-K15444511 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.21388 Hair follicle bulge TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.614 CA1 field, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.11335 REST_01_338 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.6423 testis_7a HPA Tissue Sample Gene Expression Profiles 1.0 1.23765 CEP135 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.8198 cytoplasmic part LOCATE Predicted Protein Localization Annotations 1.0 null Leukocyte disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.079 cs87 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.429 oaw42 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.982 H3K4me3_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-T6MN-0008-SM-4DM7H GTEx Tissue Sample Gene Expression Profiles -1.0 -0.917983 ventrolateral prefrontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.04687 abnormality of the genital system GWASdb SNP-Phenotype Associations 1.0 0.0996 GSE112762,GSE112767_2_v_0_dgcr8_mouse RummaGEO Gene Perturbation Signatures -1.0 null keratocystic odontogenic tumors GAD Gene-Disease Associations 1.0 null EPLC272H CCLE Cell Line Gene CNV Profiles 1.0 1.33365 H3K4me3_kidney epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null abnormality of male external genitalia GWASdb SNP-Phenotype Associations 1.0 0.238005 neurodevelopmental delay HPO Gene-Disease Associations 1.0 null abnormality of the thorax HPO Gene-Disease Associations 1.0 null neoplasm of head and neck GWASdb SNP-Phenotype Associations 1.0 0.638004 BRD-K55069932 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.97554 SNU1033 CCLE Cell Line Gene Expression Profiles -1.0 -2.18732 Reproductive organ cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.703 GSE159728,GSE159730_0_v_1_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE162739_4_v_1_bap1_mouse RummaGEO Gene Perturbation Signatures 1.0 null POLR2AphosphoS5_PFSK-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1428 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.09649 Orbital Cyst DisGeNET Gene-Disease Associations 1.0 null short thumb HPO Gene-Disease Associations 1.0 null BRD-K73688688 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.18013 BRD-K61168922 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.56764 Prostate adenocarcinoma_PRAD_TCGA-2A-A8VX-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE171179,GSE171181_0_v_1_e7107_human RummaGEO Drug Perturbation Signatures 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-7128-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cytoplasmic vesicle LOCATE Curated Protein Localization Annotations 1.0 null HCC1419 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.901428 gut epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.272997 Lower respiratory tract disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.607 GTEX-XUZC-0005-SM-4BOQ8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.988028 pancreas HPA Tissue Gene Expression Profiles -1.0 -1.14528 SMAD1 ChEA Transcription Factor Targets 1.0 null nucleus of the diagonal band, left, vertical division Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.976947 Pallister-Hall syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.418 GTEX-VUSG-0006-SM-3GIK9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08511 Lung adenocarcinoma_LUAD_TCGA-91-6840-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ChIP_KLF4_18358816 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Ameloblastoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.528 TAF1_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ETV1-20927104-GIST48-HUMAN ChEA Transcription Factor Targets 2022 1.0 null decreased lymphocyte cell number IMPC Knockout Mouse Phenotypes 1.0 null Neuroectodermal tumor DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.331 TF1 CCLE Cell Line Gene CNV Profiles 1.0 1.67931 globus pallidus, external segment, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.961859 MAZ_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TASOR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.39955 organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.663578 H3K4me3_fibroblast of mammary gland_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ARR3 Pathway Commons Protein-Protein Interactions 1.0 null LSM12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.27631 KM12 BioGPS Cell Line Gene Expression Profiles 1.0 0.908607 Thyroid gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 VI, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.890941 GSE198165,GSE198166_6_v_11_zfp266_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-QMRM-0005-SM-3NB2A GTEx Tissue Sample Gene Expression Profiles -1.0 -0.875045 EPI-1571-1 (NEDD8) NURSA Protein Complexes 1.0 null flumetasone-2551 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null KLF4-18555785-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null abnormal immune system morphology MPO Gene-Phenotype Associations 1.0 null Perturb_7980_KD_Kmt2d_SRP253323 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -11.588 pallidohypothalamic nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.927651 stratum pyramidale of caudal CA2 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.900377 phenylpropanolamine-6699 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null H3K4me3_CD4+ CD25- CD45RA+ Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Immune system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.473 plantar pits HPO Gene-Disease Associations 1.0 null Sensory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.56 GTEX-R55G-0006-SM-2TC6O GTEx Tissue Sample Gene Expression Profiles -1.0 -2.28241 Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A815-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4717-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 GSE238018_1_v_0_mxra8_human RummaGEO Gene Perturbation Signatures 1.0 null Dermal papilla TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.42 SF3B2 Pathway Commons Protein-Protein Interactions 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HW-A5KK-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null outer CP in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.69506 dorsolateral prefrontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.865136 NFYB_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Small_Intestine-plasma cell Tabula Sapiens Gene-Cell Associations 1.0 1.07147 GSE71674,GSE71676_0_v_2_cbfa2t2_mouse RummaGEO Gene Perturbation Signatures -1.0 null SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22468 BRD-K32037893 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.66599 Hypertrophy CTD Gene-Disease Associations 1.0 1.21727 abnormal bone marrow cell morphology/development MPO Gene-Phenotype Associations 1.0 null jaw TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.512957 CTCF_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-V1D1-2126-SM-4JBH4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.99222 Endometrial cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.019 GNRH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43624 H3K4me3_SK-N-SH_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null autosomal genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.786394 PMC4325629__F2 PFOCR Pathway Figure Associations 2023 1.0 null GTEX-VUSH-0005-SM-3NB2H GTEx Tissue Sample Gene Expression Profiles -1.0 -0.824678 primary visual cortex (striate cortex, area V1/17)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.54811 cerebellar cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.944589 Neurofibromatosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.228 KM12 CCLE Cell Line Gene Mutation Profiles 1.0 null BRD-K17852428 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.37702 cerebellum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.361901 496100562_FWM_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.18342 binding GO Molecular Function Annotations 2015 1.0 null H3K4me1_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81H-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.559 TCF12 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.1008 no abnormal phenotype detected MPO Gene-Phenotype Associations 1.0 null BRD-K66939340 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.14048 KCTD3 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_fibroblast of foreskin _hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H2AFZ_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-QH-A870-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null juvenile TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.286026 H3K27me3_cardiac mesoderm_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Endometrial gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.667 BT-20 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.15227 HSP90AA1 Pathway Commons Protein-Protein Interactions 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A6HO-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null decreased hemoglobin content MPO Gene-Phenotype Associations 1.0 null aplasia/hypoplasia involving bones of the thorax HPO Gene-Disease Associations 1.0 null Microcephaly DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.109 GSE229914_1_v_3_keap1_human RummaGEO Gene Perturbation Signatures 1.0 null Hair follicle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.997 H3K27ac_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Miracidium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.739 POLR2A_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null PCDHB8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.23506 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19B-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CRCGN008_HEPG2_24H:E07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.2495 ZBTB7A_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHAGO-K-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.2525