association	dataset	threshold value	standardized value
cellular response to cytokine stimulus	GO Biological Process Annotations 2025	1.0	null
IL17RB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62731
PMC8062726__F7	PFOCR Pathway Figure Associations 2023	1.0	null
GSE178714_6_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
DAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11101
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.918
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4281
response to interferon-beta	GO Biological Process Annotations 2023	1.0	null
WASHC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53296
NEURL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86636
OLIG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.2264
GSE218819_2_v_1_kdm5b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ATF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.765
SOX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94505
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0993
SCGB3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72848
IDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01472
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.459
NNT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48938
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.8374
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1367
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01001
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7821
GSE215461_0_v_1_topotecan_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE234637_3_v_0_ikzf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cellular response to virus	GO Biological Process Annotations 2025	1.0	null
SLC35E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12272
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.949
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3283
ZSCAN20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65085
GSE151090_2_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
negative regulation of protein-containing complex assembly	GO Biological Process Annotations 2023	1.0	null
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2926
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.8771
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9617
CMTM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01934
KDM5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88617
negative regulation of AIM2 inflammasome complex assembly	GO Biological Process Annotations 2023	1.0	null
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.7933
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.2135
PGM2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47571
UCHL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91827
HMBOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0689
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	140.666
PRDM12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11937
ATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1077
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6136
GSE168097_3_v_2_epinephrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1463
regulation of protein-containing complex assembly	GO Biological Process Annotations 2023	1.0	null
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7933
cellular response to interferon-beta	GO Biological Process Annotations 2023	1.0	null
GSE117212,GSE117214_0_v_1_zbtb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
C3orf52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66221
FANCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32228
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6344
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.8952
GSE193249_0_v_1_gpx8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7163
BCAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27404
ZNF565	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59642
MGA::EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1177
RPS20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51368
DPRX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9208
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2581
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2945
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.8475
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7701
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.8981
NUDT22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46131
cellular response to cytokine stimulus	GO Biological Process Annotations 2023	1.0	null
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9667
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7389
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.008
regulation of protein-containing complex assembly	GO Biological Process Annotations 2025	1.0	null
SNAPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43787
NOD-like receptor signaling pathway	KEGG Pathways 2026	1.0	null
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2252
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1678
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.34
PROSER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57375
MFSD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91428
FOSB::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6118
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2233
TEX261	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38809
GSE248935_1_v_0_cd14_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1567
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6884
OLIG3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.2464
DCP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22866
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5957
GSE123943_1_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.8636
GSE162892_4_v_5_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
SHISAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63327
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9285
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.6687
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.977
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1781
FOXD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.35
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6533
OLIG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.8048
GATA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9334
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.6623
GSE201309_5_v_7_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9706
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.0967
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8718
DMRTA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5092
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.138
cellular response to virus	GO Biological Process Annotations 2023	1.0	null
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2555
FBXL22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8536
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9188
NTMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83647
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4877
GSE178714_6_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8292
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.616
PRRX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69979
GSE234637_3_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NEUROG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.8063
TMEM151A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26996
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9638
ATL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41825
regulation of AIM2 inflammasome complex assembly	GO Biological Process Annotations 2025	1.0	null
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.4248
DBP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0322
NRL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.0704
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.792
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5907
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6382
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.5724
DGKK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92534
PMC8062726__F7	PFOCR Pathway Figure Associations 2024	1.0	null
GSE175787_4_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1138
GSE242333_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE188458_2_v_1_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6258
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0673
SETD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34771
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.2159
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2593
ZKSCAN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0398
GSE157894_1_v_0_cystine_human	RummaGEO Drug Perturbation Signatures	1.0	null
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0243
GSE221327_8_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
negative regulation of inflammasome-mediated signaling pathway	GO Biological Process Annotations 2025	1.0	null
regulation of AIM2 inflammasome complex assembly	GO Biological Process Annotations 2023	1.0	null
TSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62746
GSE221327_5_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
ARHGAP27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58979
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.6505
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1285
cellular response to interferon-beta	GO Biological Process Annotations 2025	1.0	null
LGI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39423
POLH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22551
EBF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71149
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3779
GSE127916_1_v_2_nras_human	RummaGEO Gene Perturbation Signatures	1.0	null
SCML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61818
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7695
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3308
GSE185872_0_v_1_methotrexate_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE137325_3_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9931
negative regulation of cellular component organization	GO Biological Process Annotations 2023	1.0	null
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3636
GSE149901_2_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3623
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.6086
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7659
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.1697
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4199
HSPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8463
KANK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09696
GSE133516_0_v_6_kat7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.3501
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1275
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7896
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.762
GSE118816_0_v_3_myo1c_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6411
ZNF189	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1215
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.692
ATOH7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.2129
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.6341
HLX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98542
POU3F4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85117
GSE202434,GSE202438_7_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
negative regulation of cellular component organization	GO Biological Process Annotations 2025	1.0	null
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19429
HMG20A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64166
GSE212330_1_v_0_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE186647,GSE217288_1_v_7_hnrnpc_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.1297
CILP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68263
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0327
ATOH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25892
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1659
DRGX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42145
TCF21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7159
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9034
ZSCAN29	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5021
GSE128634,GSE128636_1_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE218060_7_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE127916_1_v_4_nras_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.0229
PMC12518476-10067_2025_7574_MOESM9_ESM.xlsx-Sheet2-RNAseq_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
response to interferon-beta	GO Biological Process Annotations 2025	1.0	null
GSE165548_2_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE178714_1_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8347
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.9482
TEF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0477
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9456
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3836
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1524
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0438
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.5211
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.811
BHLHE23	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.7902
TRIM21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9329
GSE178714_1_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	85.9313
negative regulation of protein-containing complex assembly	GO Biological Process Annotations 2025	1.0	null
SLU7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10788
negative regulation of AIM2 inflammasome complex assembly	GO Biological Process Annotations 2025	1.0	null
BCL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11524
MCUR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75065
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5005
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	91.1756
SOX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6579
BHLHA15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.2217
RIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47495
GSE127261_1_v_2_ezh2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HOXB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1791
RET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61594
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7602
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0793
HOXC11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8649