association	dataset	threshold value	standardized value
HIF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74489
NPTX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85465
Bed nuclei of the stria terminalis, anterior division, rhomboid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14817
GSE210770_0_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE183271_4_v_3_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TWIST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32192
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-3.18039
GSE185944_5_v_4_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GU-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SEC24C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15747
HES7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51707
Uvula (IX)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06366
CTCF_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP1	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-515-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
ZNF266	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37058
PLEKHA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55012
NDUFAF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7873
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08526
layer V of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.43796
TET1-21490601-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Dorsal column nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10904
intermediate stratum of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25079
GSE217694_4_v_0_pold1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FBXO10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61347
SERPINB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19324
mantle zone of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33857
Siddiqi syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.921
PMC4269325-NIHMS634665-supplement-supp_table4.xls-H3K27me3_TRIM37_KD-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	229.643
LSM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18706
r11 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78632
SMARCA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98444
NCI-H460	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TCF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7774
short insular gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08025
Brain Lower Grade Glioma_LGG_TCGA-DU-6395-01A-13R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OS-01A-12R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-532-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RJ-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1286	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE231648_1_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TMEM150A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40047
TCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21386
PITPNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79533
Septohippocampal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66924
ACADS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72714
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5098-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TP53-23651856-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ZBTB39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88537
LPAR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17642
CEBPB	ENCODE Transcription Factor Targets	1.0	null
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.158
superficial stratum of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.46231
NB7	DepMap CRISPR Gene Dependency	1.0	3.94427
negative regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
ICAM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28791
GSE67266_7_v_3_etoposide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SRY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.31332
TBC1D14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8319
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.51671
ZNF705D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79553
MRPL50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64013
SATB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5345
KM-12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18098
CNOT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64595
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5885-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF274	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18775
RKN	CCLE Cell Line Gene CNV Profiles	1.0	1.57772
Acute Myeloid Leukemia_LAML_TCGA-AB-2849-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LHX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45208
ETFBKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87905
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r8 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4514
SKNMC	DepMap CRISPR Gene Dependency	1.0	5.83082
HARA	CCLE Cell Line Gene Expression Profiles	1.0	1.49479
Ciliary pocket collar	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.529
Anterior cingulate area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39918
r2 part of vestibular nucleus Y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0392
r2 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08811
NT5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22265
hsa-miR-335-5p	MiRTarBase microRNA Targets	1.0	null
DUSP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16347
posteroventral (inferior) parietal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.01639
regulation of macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
Spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06648
GMPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85234
Brain Lower Grade Glioma_LGG_TCGA-DU-5847-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55587
GSE228106_3_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
SP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00329
CYB5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57733
STAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.281
KANK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07627
Basic cell groups and regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07061
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.856351
HACD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83425
S1PR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60934
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06796
FGF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49025
ZNF814	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30862
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61O-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.9066
IGF2BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66289
OXSM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65849
Dorsal peduncular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.53729
CTCF-31629814-HEPATOCYTES-MOUSE-TYROSINEMIA	ChEA Transcription Factor Targets 2022	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.919344
TRPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51952
HLX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98542
ZNF449	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4984
KIAA0753	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38255
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17855
FOXI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52635
Anterior olfactory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57276
MFSD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66015
Frontal pole, cerebral cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41519
GSE158502,GSE158506_3_v_0_fat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
malignant glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.246799
Kidney Chromophobe_KICH_TCGA-KM-8442-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r10 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14163
Bed nuclei of the stria terminalis, anterior division, ventral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05085
Rectum adenocarcinoma_READ_TCGA-DY-A1DE-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_13570_KD_Islr_SRP160431	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4FB-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.8499
RDH11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67712
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCallEPC1-PHF1_H3K27me3_k562-ENSEMBL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16737
intermediate stratum of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45247
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49006
KCNG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58748
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1HY-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CENPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45888
ventrolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.969403
RTL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20041
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mesothelioma_MESO_TCGA-SC-A6LN-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82013
POLR2AphosphoS2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5902
HMX1_Deficiency_GDS4810_324_mouse_Retinas of C57BL/6J	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
Johnston's organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.03
HGS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71978
POMC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34934
superficial stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17104
inner SZ in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.828643
mantle zone of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4875
H3K23ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
PMC8569982-41065_2021_205_MOESM1_ESM.xlsx-mono_THP1_a2b_tpm1-gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05581
TM9SF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34906
PLAGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0719
PRRC2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.81937
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96296
Bed nuclei of the stria terminalis, anterior division, fusiform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09562
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE248858_1_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ARHGAP23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97628
HCC1569	CCLE Cell Line Gene CNV Profiles	1.0	1.98148
H3K27me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_10774_KD_Csde1_SRP383422	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.50891
lower (caudal) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09399
amygdaloid complex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13631
Lung adenocarcinoma_LUAD_TCGA-55-8513-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.910666
Lung adenocarcinoma_LUAD_TCGA-97-7941-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS766T	CCLE Cell Line Gene CNV Profiles	1.0	2.19036
Perturb_14759_KD_LATS1/LATS2_SRP345234	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.91725
C3orf80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11113
Monogenic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.541
ELOB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23514
Perturb_16535_KO_Repin1_SRP108279	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.4558
ASPSCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92256
small intestine	GTEx Tissue Gene Expression Profiles	1.0	0.999555
hsa-miR-4297	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
CEBPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71397
SIK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02479
Lung adenocarcinoma_LUAD_TCGA-55-8614-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158197_0_v_11_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Primary somatosensory area, lower limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66924
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
spinal trigeminal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.54715
outer plexiform zone in extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.923981
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2444	COSMIC Cell Line Gene CNV Profiles	1.0	2.30944
GCLM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49046
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ABHD14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49069
layer 3 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75137
ZNF729	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93301
KMH2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39569
Depression	DisGeNET Gene-Phenotype Associations	1.0	null
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80352
Bipolar disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
OLFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05065
HCC1395	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.820255
Lung squamous cell carcinoma_LUSC_TCGA-60-2709-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LRP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2312
EAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37889
WM3211	DepMap CRISPR Gene Dependency	1.0	2.17151
Rectum adenocarcinoma_READ_TCGA-AG-3902-01A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE226316_1_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Diabetes Mellitus, Type 2	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE211286_7_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF443	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67201
H3-5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89653
8MGBA	CCLE Cell Line Gene Expression Profiles	-1.0	-1.76394
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Retrosplenial area, ventral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48875
mantle zone of r1BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24653
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10426
WASHC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93155
RUNX1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
SCRN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88138
FOSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07889
laterodorsal part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.840744
ESPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49004
VAX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70924
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.934939
septostriatal part of the olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12278
CNBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10236
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4713-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06112
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22037
GSE156907,GSE160237_1_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-A4D0-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHCHD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.69447
PMC7064149-CAM4-9-2062-s004.xlsx-Table_S5-Table_S5_DEGs_between_low-_and_high-FOXP4-AS1_expression_groups_in_PDAC_tumor_tissues_FOXP4	Rummagene Transcription Factor Associations 2026	1.0	null
ZIK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29788
Lung adenocarcinoma_LUAD_TCGA-50-5935-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29944
AGPAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.43746
P2RX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01295
NUMA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53373
KLF4-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_11337_KD_Ankrd35_SRP214047	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4814
inner SZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.947271
SAPCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47001
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
negative regulation of proteolysis	GO Biological Process Annotations 2015	1.0	null
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.76061
20174566-TableS1	GeneSigDB Published Gene Signatures	1.0	null
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
peduncular (caudal) hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09923
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10652
Perturb_4787_KD_Akap8_SRP075747	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.59449
TOP3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6302
Podocyte_Kidney_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
PDE12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98161
Perturb_11080_KD_Gls2_SRP326675	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.15265
SETD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.63873
EPM2AIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19005
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.0436
FOS	ENCODE Transcription Factor Targets	1.0	null
KHDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57491
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0963
PUR1	MotifMap Predicted Transcription Factor Targets	1.0	null
MFSD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49941
ZNF286A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49656
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-2cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
caudal subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07077
CUL4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72991
ZDBF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61645
Field CA3, stratum pyramidale	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76937
TMEM88B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75684
MAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79795
P300-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SR-786	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.00801
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.4799
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.52134
GSE158975_0_v_1_spp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NKX2-4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15422
posterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15579
enzyme regulator activity	GO Molecular Function Annotations 2015	1.0	null
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TIGD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28552
PNMA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95078
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE139987_1_v_0_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
AGS	CCLE Cell Line Gene Expression Profiles	1.0	1.46511
Secondary motor area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64698
maturity-onset diabetes of the young	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.648
RASD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37348
RIPOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08263
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.923215
Spinal nucleus of the trigeminal, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02165
KPNA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93341
DOLPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23042
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33731
TRPM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84564
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22
colon	GTEx Tissue Gene Expression Profiles	1.0	1.37202
TMEM30A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57858
Bed nuclei of the stria terminalis, posterior division, transverse nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58251
ZNF408	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36166
ELOF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03639
ACTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78616
ventrolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10652
hsa-miR-1224-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
ZNF486	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05111
HT-144	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02513
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
EFCAB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00577
Perturb_6127_KO_NEUROD1_SRP170936	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.70518
Agranular insular area, ventral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69835
GSE122101,GSE122103_3_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-2cell_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE225083_0_v_1_kras_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6494-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58903
RAD17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2047
Pancreatic adenocarcinoma_PAAD_TCGA-LB-A7SX-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KP1N	DepMap CRISPR Gene Dependency	1.0	2.94741
CEP68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78549
SLC66A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40937
GSE88819_3_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JHOM1	DepMap CRISPR Gene Dependency	1.0	2.58436
ZNF181	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85926
MRPS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86232
NCIH1648	CCLE Cell Line Gene CNV Profiles	1.0	1.34435
RAB17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93004
r11 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26463
OB olfactory fiber layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8891
NOM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42354
Sarcoma_SARC_TCGA-QQ-A5VA-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.841745
Prelimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30139
IRX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88158
regulation of primary metabolic process	GO Biological Process Annotations 2015	1.0	null
SBNO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37814
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15857
UCHL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50787
GSE232631_4_v_3_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22806
CAMA-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.089
nrf1_22586274_liver_lof_mouse_gpl4134_gse35124	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.038626
REEP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96021
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.52601
NCI-H727	COSMIC Cell Line Gene CNV Profiles	1.0	2.30944
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-2cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
OCIMY7	DepMap CRISPR Gene Dependency	1.0	7.94991
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
HDGFL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45667
SYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22533
G142	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19156
ATF6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15416
ACOT13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70082
Entorhinal area, lateral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17183
ESCO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5642
Sarcoma_SARC_TCGA-DX-A2J4-01A-32R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_8411_KO_Srsf1_SRP252896	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.8552
superficial stratum of ERCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50953
JIMT-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.30944
VZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.898006
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IX-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA-MB-435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34714
temporal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.991631
GSE231648_1_v_5_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.188938
PTPRCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33445
TRIM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57568
maturity-onset diabetes of the young type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.737
Brain Lower Grade Glioma_LGG_TCGA-HT-7480-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KON	COSMIC Cell Line Gene CNV Profiles	1.0	2.30944
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.9291
Ebf2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.8834
DHRS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70485
regulation of protein processing	GO Biological Process Annotations 2015	1.0	null
C11orf54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53885
CAMKV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47163
EHD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21695
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C15orf39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00018
KURAMOCHI	COSMIC Cell Line Gene CNV Profiles	1.0	2.30944
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30466
Inherited metabolic disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.751
SPATA20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96548
DU4475	CCLE Cell Line Gene Expression Profiles	1.0	3.40796
mantle zone of r10BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25961
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AH-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCK-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25988
Field CA3, stratum lacunosum-moleculare	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05312
PEA15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67979
ZNF816	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22715
ACBD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78442
medial pallium (hippocampal allocortex)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19709
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9241
PMC7616986-EMS181817-supplement-Supplemenatry_tables.pdf-684-PTF1A_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
Taenia tecta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52567
SLC15A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22544
TRMT10A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72682
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A4AX-01A-12R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4389-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAP3K11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94336
600MPE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.683135
claustrum, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12707
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.57294
SULT1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91906
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
EIF2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59208
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.16439
MDAMB134VI	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.7052
periventricular stratum of r2Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04031
MYORG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53419
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.906643
periventricular stratum of r1Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1857
Anterior olfactory nucleus, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.01916
ASCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43215
GSE148695,GSE167281_2_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ETS1-21867929-TH2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Schizophrenia	DisGeNET Gene-Disease Associations	1.0	null
PHACTR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47187
SAMD4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23147
layer 1 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21148
AGRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95411
METTL7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88016
Primary somatosensory area, lower limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17044
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051558
HAPLN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54551
ONECUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38701
H3K27me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GNA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42587
ATG2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0043
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.79953
PELI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99235
GSE118816_2_v_3_myo1c_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE63857_3_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GORAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01581
NCIH854	CCLE Cell Line Gene Expression Profiles	1.0	1.5377
NRIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07055
SMIM10L2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56625
Perturb_10990_KO_H1foo_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.40582
CORL24	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63234
SKMEL31	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52008
CAOV3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7517
ZNF678	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34909
ANO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98517
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.22979
RTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15194
Spinal nucleus of the trigeminal, oral part, middle dorsomedial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43912
Sarcoma_SARC_TCGA-SI-A71O-06A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TP53	ChEA Transcription Factor Targets	1.0	null
AGXT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49361
PMC3879300-pone.0084292.s002.xlsx-SPD_dataset-Gene_symbol_HOXD13	Rummagene Transcription Factor Associations 2026	1.0	null
regulation of hydrolase activity	GO Biological Process Annotations 2015	1.0	null
NR1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78131
Peptidase inhibitor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.136
oculomotor nuclear complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07214
FUOV1	CCLE Cell Line Gene Expression Profiles	-1.0	-3.22826
MZ in retrosplenial cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.68832
GSE234637_2_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_11258_KO_Mkp1_SRP169858	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.3572
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uvula (IX), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15
IFFO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.65541
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.4139
Agranular insular area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31577
Taenia tecta, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.80384
BRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26258
NCI-H2110	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86119
ZNF391	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29373
BANF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75243
ATP6V0B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54774
DUT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65798
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55879
Perturb_11285_KO_Nr1d1/Nr1d2_SRP241717	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.76646
UNKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35913
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.17815
Brain Lower Grade Glioma_LGG_TCGA-HT-7884-01B-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7295
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.78255
KCTD15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33987
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62277
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.983202
septopallidal core nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1572
ERCC6L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.68397
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A7IN-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
p95	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.523
hsa-miR-3179	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
HPRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07963
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.868834
Bed nuclei of the stria terminalis, anterior division, oval nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1452
RYR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41114
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1025
Nucleus of the solitary tract, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18083
CTCF-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Orbital area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13871
TE-8	COSMIC Cell Line Gene CNV Profiles	1.0	2.30944
GSE158197_2_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mantle zone of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.46073
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.962278
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.67623
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.42338
H3K27me3_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Troyer syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.061
ZNF133	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47282
CDT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63929
entorhinal cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51306
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R8-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1422
ChIP_MTF2_20144788	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
peptidase inhibitor activity	GO Molecular Function Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-75-7030-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of CA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46833
TBCCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72068
Colitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.02
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JX-A3PZ-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.959954
Parasolitary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00069
peptidase regulator activity	GO Molecular Function Annotations 2015	1.0	null
Perturb_10637_KO_Sip1_SRP028877	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
RAD21_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RIPK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48191
PPP1CB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5798
DNMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12201
ENTPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4305
GSE242096,GSE242098_1_v_0_med1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CENPJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62373
hsa-miR-501-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Primary somatosensory area, trunk, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14696
Type 2 diabetes	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.1
NPIPA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85196
lateral part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25831
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.911695
Uvula (IX), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0012
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.98254
ventrolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03647
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.8013
SIN3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79896
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-5397-01A-01R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8326-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SAFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12149
NRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03155
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.829273
HCC1833	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57128
PAWR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13426
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.37246
negative regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NBPF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32542
ventral reuniens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19175
Lung adenocarcinoma_LUAD_TCGA-55-8097-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.58996
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Parastrial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08407
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4696-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56106
NELFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18391
NAGPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1724
interstitial nucleus of Cajal, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.99277
Caudatenucleus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.62551
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45539
Lung squamous cell carcinoma_LUSC_TCGA-98-A53D-01A-32R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary T cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.01147
STEAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3331
MFAP3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82568
PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S9-ZNF384_SpecDMCs-Unnamed_3_ZNF384	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4779	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Skin Cutaneous Melanoma_SKCM_TCGA-OD-A75X-06A-12R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LHFPL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12934
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40684
TEPSIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89934
IDH3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78144
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6133-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37635
ADM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18578
RIPPLY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06532
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.63689
NR5A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67849
SPPL2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06208
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61224
BORCS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25803
mediodorsal nucleus of thalamus_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.993348
H3K4me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H2BC12L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18198
GSE88819_3_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VEGFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4993
intermediate stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32698
SH2B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6517
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0021
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32539
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9352
SBDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86424
SLC66A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18322
KDM5A	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GRK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58553
striatum_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.52429
SNUC1	CCLE Cell Line Gene CNV Profiles	1.0	1.51183
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
central gray of the pons, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26697
NUGC2	CCLE Cell Line Gene CNV Profiles	1.0	1.52413
ALKBH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00212
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.047
CXCL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12063
Ulcerative colitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.02
Lung adenocarcinoma_LUAD_TCGA-55-6975-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUCKS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.316
B3GNT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56531
ATM_KD_GSE54268_663_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BL1098 (DYRK3)	NURSA Protein Complexes	1.0	null
Autoimmune disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.02
CERS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17536
SERHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7542
CNN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77791
acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.167224
MEOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80627
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01174
CEBPB_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51K-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Waist-to-hip ratio adjusted for BMI (additive genetic model)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.7
BLVRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10303
FAM199X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16893
pineal_day	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.847563
CAL29	CCLE Cell Line Gene CNV Profiles	1.0	1.76839
CASZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70972
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.40863
DKMG	DepMap CRISPR Gene Dependency	1.0	2.15218
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE185944_5_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.59576
angular gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.996901
FIZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.941
layer IIIu of area 35r	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32086
LTA4H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0555
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLHDC7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63323
Brain Lower Grade Glioma_LGG_TCGA-F6-A8O3-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE131377_1_v_0_spocd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TMEM18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17187
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.56457
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Protease inhibitor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.151
PTGES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99797
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.40471
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE173232_1_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
bed nucleus of stria terminalis, lateral amygdaloid division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00453
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0218
mantle zone of S	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06571
Bed nuclei of the stria terminalis, anterior division, juxtacapsular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1753
S100A16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94671
OSC20	DepMap CRISPR Gene Dependency	1.0	2.52648
CDC42SE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61871
MTCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91853
C2BBE1	CCLE Cell Line Gene CNV Profiles	1.0	1.5031
GSE216538_1_v_6_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HS600T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.79362
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3JX-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMAD3	MotifMap Predicted Transcription Factor Targets	1.0	null
ZNF776	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71584
Perturb_10799_KO_Xbp1_SRP197108	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.39962
r5 part of the oral Sp5 subnucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17104
GSE238116_1_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-3616-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
HCC1419	DepMap CRISPR Gene Dependency	1.0	4.40347
TAF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8879
negative regulation of catalytic activity	GO Biological Process Annotations 2015	1.0	null
ZNF444	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16484
root	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07061
IGSF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9006
negative regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
CCDC59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83665
GSE148692,GSE148695_7_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.996374
CALHM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44369
MELK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56256
HCC202	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71802
CDKN2AIPNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51918
ETHE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27391
MEAF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.299
CC2D1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61403
Entorhinal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08868
abnormal skeletal muscle fiber morphology	MGI Mouse Phenotype Associations 2023	1.0	null
PORCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02534
retroparafascicular area of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.45731
DCK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65705
ZNF441	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54866
hsa-miR-3653	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
BHLHE40	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6013
Taenia tecta, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93315
Abdominal obesity-metabolic syndrome 1	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.541
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26265
Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NN-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSMD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24113
hsa-miR-4476	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
MRPL24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92579
C21orf58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30445
Lung adenocarcinoma_LUAD_TCGA-55-7284-01B-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.831438
SLC25A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76046
Spinal nucleus of the trigeminal, oral part, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1009
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.342
MAP3K21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64453
FBLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67381
FAM43A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37521
r8 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09794
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Pneo-r__CIC-1n_h-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.834458
CASP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86666
HCC1954	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.66384
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.5922
CEP76	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53425
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.24926
Perturb_10635_Mut_Cryaa_SRP104440	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.19876
AIRE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82072
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.89483
secondary prosencephalon	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05312
KCTD17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91449
GA10	CCLE Cell Line Gene Expression Profiles	1.0	2.34836
posterior (caudal) superior temporal cortex (area 22c)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03659
GSE189653,GSE203344_2_v_0_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
N4BP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44155
C1orf109	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20626
DNASE2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70778
BMF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90655
layer 3 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27085
GSE148193_1_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A3PJ-01A-21R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7203
ZBTB44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83191
NICN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44003
basal reticular formation of p1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25849
BT-474	COSMIC Cell Line Gene CNV Profiles	1.0	2.30944
negative regulation of molecular function	GO Biological Process Annotations 2015	1.0	null
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.891007
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.68393
ACACA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27565
septopallidal shell area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06424
CUL4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.45047
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
Dorsal peduncular area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.20114
GSE188599_1_v_10_resolvin e1_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF682	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.7845
SLTM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10093
ADAMTS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25943
ARPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08953
TYKNU	DepMap CRISPR Gene Dependency	1.0	4.86763
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.11618
ASPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10596
Primary somatosensory area, mouth, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41195
Rectum adenocarcinoma_READ_TCGA-F5-6571-01A-12R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100315_TCx_no dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	10.6613
CPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00659
496100476_TCx_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	10.2875
RSF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.558
KRT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87305
TRAPPC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34575
medial part of r8B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24358
CEP78	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74984
Lung adenocarcinoma_LUAD_TCGA-55-7227-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
APEX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68043
Acute Myeloid Leukemia_LAML_TCGA-AB-2941-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAB41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15397
PSMC3IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98622
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35661
abnormal quadriceps morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Perturb_2950_KD_Myog_DRP004738	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.76303
superficial stratum of r7Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03534
FBXO17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9938
layer 1 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16904
TCF3	ENCODE Transcription Factor Targets	1.0	null
HUS1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90663
MTERF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22479
Lung squamous cell carcinoma_LUSC_TCGA-46-3767-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE244072_4_v_1_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9195629-Table1.xlsx-Supplementary_Table_1-JUN_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
WRNIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02755
mantle zone of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51306
STK31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2712
GSE96641_3_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4272	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GSE148692,GSE148695_2_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FSTL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08894
CSB-26484114-CHIP-SEQ-FIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Autosomal genetic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.541
Ventral pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1958
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0571
OIP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17955
TE-10	COSMIC Cell Line Gene CNV Profiles	1.0	2.30944
regulation of peptidase activity	GO Biological Process Annotations 2015	1.0	null
USF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80094
hsa-miR-3154	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
ERG28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66298
Kidney Chromophobe_KICH_TCGA-KN-8435-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BT474	CCLE Cell Line Gene CNV Profiles	1.0	2.2909
TBX21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55736
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-2661-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1734	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02803
LXF289	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44567
Perturb_13478_KO_GPR174_SRP400800	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	14.5324
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A3JL-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU81	CCLE Cell Line Gene Expression Profiles	-1.0	-2.16419
MYO1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57953
SUPT5H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.1279
hsa-miR-1260b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
medial part of r1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24653
KATNBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37009
GSE173578_1_v_0_atf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
L33	DepMap CRISPR Gene Dependency	1.0	4.75465
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.64103
Perturb_10309_KO_Nos3_SRP286435	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.80602
SOX30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06752
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.37684
male reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.213471
Midbrain, behavioral state related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21703
Prostate adenocarcinoma_PRAD_TCGA-EJ-5507-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_1408_KO_Pth1r_SRP341470	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE232631_5_v_2_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HPAFII	CCLE Cell Line Gene Expression Profiles	1.0	1.56978
CAP domain	InterPro Predicted Protein Domain Annotations	1.0	null
RH30	CCLE Cell Line Gene Expression Profiles	-1.0	-1.53808
H3K27me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16076
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5370-01A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anterior cingulate area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45585
H413	DepMap CRISPR Gene Dependency	1.0	3.47155
Infralimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.50045
Lung squamous cell carcinoma_LUSC_TCGA-85-6175-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12278
P3H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45626
ESR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68699
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ESRRB-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SKN	DepMap CRISPR Gene Dependency	1.0	2.40341
FAM133B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71279
Field CA3, stratum oriens	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.00405
GSE211286_4_v_6_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE107505_1_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CDC42EP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04493
JM1	CCLE Cell Line Gene Expression Profiles	1.0	1.43098
Agranular insular area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32077
WM1799	DepMap CRISPR Gene Dependency	1.0	2.58141
PLP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56899
SERINC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24073
SLC16A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66662
abducens nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13364
H3K27me3_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer I of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.892363
NR2F2_01_07	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.12938
C2CD4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32719
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5QA-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.84203
RERFGC1B	DepMap CRISPR Gene Dependency	1.0	8.45849
GSE235644_1_v_0_fasn_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6899
ERGIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75805
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
layer 1 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.32034
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral subdivision of BNST	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.947614
EFO-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.868834
PAFAH1B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36333
ONDA8	DepMap CRISPR Gene Dependency	1.0	4.21292
BRMS1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71298
inferior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.4336
VCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88274
NCIH1693	CCLE Cell Line Gene Expression Profiles	1.0	1.45444
hsa-miR-1260	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU216	CCLE Cell Line Gene CNV Profiles	1.0	1.69994
MT1X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96869
hsa-miR-421	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
TMEM94	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05046
Neonatal diabetes	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.112
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01065
Mus musculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23165
H3K27me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050139
BL70	DepMap CRISPR Gene Dependency	1.0	4.12667
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE226316_4_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OSBPL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33498
Perturb_14971_KD_Crebbp_SRP154933	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-17.3152
Plagl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.8523
SEMA3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54402
intermediate stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11745
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.93265
ZNF780B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69953
SLX1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8874
GSE157777_1_v_3_foxa3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE101239_3_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9775089-biomedicines-10-03122.nxml--RUNX2_Targets_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-ND-A4WA-01A-12R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.77172
mesomere 2 (preisthmus or caudal midbrain)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04561
GSE130081,GSE130082_4_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE101336_1_v_0_decitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
SR786	CCLE Cell Line Gene CNV Profiles	-1.0	-2.00861
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14944
r7 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00225
extracellular region	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE246053_1_v_2_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01065
anterodorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.977194
UBR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09696
SG in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.866355
superficial stratum of CA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47183
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.351
pontine nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17577
ZNF101	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58361
SIX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92357
NCI-H2228	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.948139
MAP3K14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45406
COQ6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9681
Midbrain raphe nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06571
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A26S-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050096
ENDOV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.33253
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_CCRFCEM_ChIP-seq_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
DHX34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93459
Pancreas	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.927405
NCIH650	DepMap CRISPR Gene Dependency	1.0	2.1511
PATU8988T	DepMap CRISPR Gene Dependency	1.0	5.04529
SKRC20	DepMap CRISPR Gene Dependency	1.0	3.17833
r10 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25768
regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21847
NCIH838	CCLE Cell Line Gene CNV Profiles	1.0	1.41021
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40684
P53-21459846-SAOS-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ANKRD39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58987
CDX2-20551321-CACO-2-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ZNF107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27108
SKM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JN-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAIP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71823
Lung adenocarcinoma_LUAD_TCGA-78-7160-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Subiculum, ventral part, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03586
CMTM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01934
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_12084_KO_Brca1_SRP050547	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
ZDHHC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62961
PLEKHA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28474
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43986
OLFML3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4405
Brain Lower Grade Glioma_LGG_TCGA-FG-5963-02A-12R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.919185
TM31	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52436
Kidney	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.04714
DMS79	CCLE Cell Line Gene CNV Profiles	-1.0	-1.90104
Perturb_10988_KO_Gnpda2_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.26828
GSE200352_5_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r1 part of vestibulocerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41974
SP in entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.5709
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.876404
LCLC-97TM1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MRPL27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95651
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.94782
POU3F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50465
MPI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32755
PMC8567280-EMBR-22-e53014-s007.xlsx-Sheet1-Nearest_genes_to_BAZ2A-bound_C2-Enhancers_BAZ2A	Rummagene Transcription Factor Associations 2026	1.0	null
ATP6V0C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24896
abnormal sarcomere morphology	MGI Mouse Phenotype Associations 2023	1.0	null
WASHC2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2585
intermediate stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10965
LIME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68582
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SB-01A-31R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OXLD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28609
PGM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84443
G2E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61599
GPR20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37241
SIX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98198
RRBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98689
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06365
HS 766T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34507
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
TUT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15192
PBX-27287812-CHIP-SEQ-EMBYONIC-LIMB-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K27me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBM15B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19351
SNUC1	CCLE Cell Line Gene Expression Profiles	1.0	1.54834
SKMEL3	CCLE Cell Line Gene Expression Profiles	-1.0	-2.18786
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.69835
GSE232564,GSE232566_0_v_2_nsd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SW1271	DepMap CRISPR Gene Dependency	1.0	4.17213
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.999283
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050139
GSE185944_0_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.910666
MT-ATP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31003
ARHGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3167
c8166	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.832
NOC4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23057
BDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46586
NR6A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.15296
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
NDEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84851
anterior cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10496
impaired skeletal muscle regeneration	MGI Mouse Phenotype Associations 2023	1.0	null
GNG14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14554
regulation of proteolysis	GO Biological Process Annotations 2015	1.0	null
primary auditory cortex (core)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.828447
KRI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15389
IFT57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2066
FAM20B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84517
IGSF9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97917
GMEB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49397
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.8338
negative regulation of peptidase activity	GO Biological Process Annotations 2015	1.0	null
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GALE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50989
RCC10RGB	DepMap CRISPR Gene Dependency	1.0	2.49599
SMARCE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40559
abnormal skeletal muscle satellite cell proliferation	MGI Mouse Phenotype Associations 2023	1.0	null
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GU-06A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-M7-A723-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SAP130	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74503
DLD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63467
ZNF513	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56502
ATP1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25545
ZNF81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27901
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.976884
ZCCHC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47826
negative regulation of macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
P2RY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92601
CCZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74446
CHD1	ENCODE Transcription Factor Targets	1.0	null
Perturb_10271_KO_Fxr_SRP343112	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.1115
reticular nucleus of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.843683
ASAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0888
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.6687
GSE189683_1_v_2_rif1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
prostate gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.318407
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.0993
ECC10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SUIT2	CCLE Cell Line Gene Expression Profiles	1.0	2.65492
ZNF708	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.5501
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.342
schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.369997
superior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.81962
r9 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66359
MDAMB436	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68512
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.59794
JURKAT	CCLE Cell Line Gene Expression Profiles	-1.0	-2.34919
MADD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20274
GSE178227_1_v_0_tet1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FAM110C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00903
anterior nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.91421
HOP-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18945
negative regulation of protein metabolic process	GO Biological Process Annotations 2015	1.0	null
Perturb_8389_KO_Rnaseh1_SRP108593	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.39162
NPW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53963
mantle zone of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24358
CDX2-20551321-CACO-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71659
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Perturb_1407_KO_Pth1r_SRP341470	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.5204
TEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40646
Perturb_8200_KD_FUBP3_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.04492
TAF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6493
CCDC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15518
RBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99555
Brain Lower Grade Glioma_LGG_TCGA-R8-A6MK-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAAP24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90451
Syndrome	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.541
ENTPD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27223
midbrain reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.06125
acetaminophen_homo sapiens_gpl6244_gse27420	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84O-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bed nuclei of the stria terminalis, anterior division, magnocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14637
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01991
H3K27me3_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPMI-7951	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.908496
HNT34	CCLE Cell Line Gene CNV Profiles	-1.0	-2.30665
KYSE520	CCLE Cell Line Gene CNV Profiles	1.0	1.38048
NEURL1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66833
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.870794
NCI-H520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1087
HT-144	COSMIC Cell Line Gene CNV Profiles	1.0	2.30944
Entorhinal area, medial part, dorsal zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35145
TMEM229A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75062
WASHC2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60736
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.833815
inferior frontal gyrus, opercular part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.49843
REL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1176
superficial stratum of S	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06817
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11372
PLA2G12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20742
interpeduncular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.17796
PHYH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72682
Perturb_11227_KO_Cldn3_SRP288282	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.69468
Lung adenocarcinoma_LUAD_TCGA-44-A479-01A-31R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AGXT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47511
BL1704 (PHB2)	NURSA Protein Complexes	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
THAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30878
TSPAN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06693
NCIH69	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78184
inner SZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09268
NPPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09419
GSE248858_1_v_2_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
LRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58624
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GGCT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32591
PEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43654
DKKL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93193
CTCF	ENCODE Transcription Factor Targets	1.0	null
medial orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1074
estradiol_mus musculus_gpl4134_gse23241	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZNF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18285
UBAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89016
WM983B	CCLE Cell Line Gene CNV Profiles	1.0	1.34462
SNU-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06893
Perturb_10949_KO_18O10Rik_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.87874
ZNF549	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.7723
PHF8-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEX261	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38809
PPIG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05138
r11 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78535
H4C14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28202
ICAM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83792
pyramidal layer of IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.46152
TNFRSF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14957
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-A5DJ-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04048
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13881
Skin Cutaneous Melanoma_SKCM_TCGA-W3-A825-06A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LDHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57969
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11372
MCF7	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.17619
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7255-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TIGD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01599
OBI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86904
PDCD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36035
Retrohippocampal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24653
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.32576
20460173-ImmPortAntimicrobials	GeneSigDB Published Gene Signatures	1.0	null
CP in rostral hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.940689
psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.368518
extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Brain Lower Grade Glioma_LGG_TCGA-FG-7643-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IJ-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of isBM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00693
SPIN2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65284
GSE53538_1_v_0_cd2bp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
induseum griseum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.4662
CEBPB-21427703-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.0493
HIF1A_DEPLETION_GDS2760_642_human_Hypoxic MCF-7 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Medullary reticular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26717
Retrosplenial area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06817
superior rostral gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.889691
UBE2E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48559
RDH14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32214
MRPL44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53121
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45T-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F8-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Islands of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24653
BCOR-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_3849_KD_TGM2_SRP194250	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.9007
SCARF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13478
Perturb_8186_KD_DNAJC21_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.80074
orbital frontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.48985
KOPN8	CCLE Cell Line Gene Expression Profiles	1.0	1.58125
ALX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60578
GATAD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84167
SPO11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38136
AHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73785
NCIH684	CCLE Cell Line Gene Expression Profiles	1.0	1.39294
GSE112760,GSE112767_4_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_3957_Mut_GSDMB_SRP350967	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.4868
ACTR3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74825
posterior (caudal) superior temporal cortex (area 22c)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09123
Perturb_2948_KD_Hnrnpk_DRP004738	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.1524
COBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7293
COL1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47188
UBXN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41911
BCL3	ENCODE Transcription Factor Targets	1.0	null
GSE79291_1_v_2_streptozotocin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TRAFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57853
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19B-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE163862_1_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
USF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74356
MTA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48679
H3K27ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SMAD1-26771354-MESC-MOUSE-STEM	ChEA Transcription Factor Targets 2022	1.0	null
Integrin alpha9-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.554
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.0162
PXDNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93826
FGD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.80797
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Field CA2, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17183
UNC13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23932
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.7345
WFDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54207
GSE200673,GSE200691_1_v_5_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8113-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TTC642	DepMap CRISPR Gene Dependency	1.0	3.46906
PHYHIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67354
inner SZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15531
GSE168596_2_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.992193
HDAC1	ENCODE Transcription Factor Targets	1.0	null
BRIX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06304
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.801236
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE179036_1_v_0_trim24_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE163920_1_v_0_sirt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
substantia nigra, pars compacta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04671
NEFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72945
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	82.742
Basomedial amygdalar nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32698
EZH2	ENCODE Transcription Factor Targets	1.0	null
HSD17B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56283
CMK86	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56145
TP53INP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4926
Perturb_14916_KO_Cd2bp2_SRP034660	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Prostate adenocarcinoma_PRAD_TCGA-HC-7745-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.20821
Pod	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.596
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Disease of metabolism	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.751
RERFGC1B	CCLE Cell Line Gene CNV Profiles	1.0	2.06165
MRPL39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3057
PRR19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75418
PSMB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62225
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040058
frontal operculum, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.970952
SNU1041	DepMap CRISPR Gene Dependency	1.0	3.18314
Cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20036
Prostate adenocarcinoma_PRAD_TCGA-J4-A67N-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC25A52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9781
intermediate stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28718
Diabetes mellitus	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.751
ZNF616	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3066
C11orf71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18014
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GR-06A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
Fetallung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.881174
H2BC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00478
Intercalated disc	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.881
VRK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68677
cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.071163
HMOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95412
Anterior olfactory nucleus, external part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12546
BCPAP	CCLE Cell Line Gene CNV Profiles	1.0	1.53296
H3K27me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE236502_2_v_0_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053047
negative regulation of cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09444
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.44759
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02274
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15401
FBXL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93405
Prelimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.73615
hsa-miR-4251	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
REPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65866
r6 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25079
TRIM32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23718
Abdominal obesity-metabolic syndrome	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.541
Orbital area, ventrolateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54451
B4GALNT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94054
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.80518
SPTAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8119
VANGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48183
Taenia tecta, dorsal part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.98231
GSE84922,GSE84924_4_v_1_sall4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TMED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62243
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SIX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48475
VPS13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53843
NR1H3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.65388
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.6064
superficial stratum of r4Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08694
IFNGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74611
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051853
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE164757,GSE164759_1_v_3_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_11053_Mut_Lmna_SRP309326	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.5854
pontine reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.900091
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052564
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61224
SPEG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74728
superficial stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00928
ZNF136	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38258
FAM200C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0341
CCDC74B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69408
lateral habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.50235
SP in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1521
MYLIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78605
DPP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.322
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A77O-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5784
CEP170	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99639
496100457_TCx_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.32291
ZNF662	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54819
OGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35072
pyramidal layer of S	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11745
dorsomedial hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.998959
CHCHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97439
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.98655
KNS62	CCLE Cell Line Gene Expression Profiles	1.0	1.40174
SESN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56921
mantle zone of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78535
KLF5-25053715-YYC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
DUXB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93697
CELSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62219
PCIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69154
GSE120370_0_v_6_thrombin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Biceps brachii	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.504
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
decreased body weight	MGI Mouse Phenotype Associations 2023	1.0	null
Linear nucleus of the medulla	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02327
TM9SF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8779
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.747436
layer III of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.837107
Perturb_11741_Mut|KO_Kras_SRP272482	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.91686
Superior colliculus, sensory related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23764
Breast Cancer_Mammary Gland Tissue_GSE3744	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.58093
PK59	CCLE Cell Line Gene CNV Profiles	1.0	2.44001
Obesity_Muscle - Striated (Skeletal) (MMHCC)_GSE5109	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.71704
SUM185PE	DepMap CRISPR Gene Dependency	1.0	3.52276
HCC38	CCLE Cell Line Gene CNV Profiles	1.0	1.42096
Psychotic Disorders	HuGE Navigator Gene-Phenotype Associations	1.0	null
ZNF418	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44598
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RNF112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23301
KANK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37854
ATP2C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63439
GAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31537
Retrosplenial area, ventral part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46488
UACC893	DepMap CRISPR Gene Dependency	1.0	15.4192
BOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83226
Amylin receptor complex 1	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.56
H3K27me3_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8421-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF516	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13297
Taenia tecta, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.98111
parolfactory gyri, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.92664
H3K27me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
SW1573	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60432
GSE233679_5_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.917668
GSE163862_0_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
dorsal part of m2A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0249
CARHSP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15493
ASB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53169
SW 1990	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22
GAP43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81913
CCDC69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99977
RNF41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7077
dorsal preisthmic part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02654
Glucose metabolism disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.751
DPY30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28789
MAP1LC3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64058
TCF3_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_RCOR3_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Field CA3, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70353
EFM192A	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59468
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.59424
Anterior cingulate area, ventral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63274
GSE233679_12_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH2085	CCLE Cell Line Gene Expression Profiles	1.0	1.83062
Lung adenocarcinoma_LUAD_TCGA-97-7938-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ESD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83845
Brain Lower Grade Glioma_LGG_TCGA-DB-5281-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TSSK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98452
ZBTB8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61313
RCHY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60952
GSE88819_3_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10138
CYB5R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18763
intermediate stratum of SePal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02272
SLC38A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31017
Bed nuclei of the stria terminalis, posterior division, interfascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02708
IFNAR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30471
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.6687
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.02
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE200352_11_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE65617_2_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC37A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34555
KATOIII	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH23	CCLE Cell Line Gene Expression Profiles	1.0	1.7282
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5KZ-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE67266_7_v_4_etoposide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
8505C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02654
layer 4 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29504
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07224
GCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92297
GSE107505_3_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LRRC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67598
Perturb_10644_KO_Gclc_SRP321080	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.85647
GNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36761
Infralimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	4.11985
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.87113
layer 2 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15521
GSE182680,GSE182683_10_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE96641_1_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08288
Lung squamous cell carcinoma_LUSC_TCGA-60-2698-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of catalytic activity	GO Biological Process Annotations 2015	1.0	null
GMCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81351
ARHGAP35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17222
TRMT44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73387
Lung adenocarcinoma_LUAD_TCGA-44-2665-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer SZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10334
NR0B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7851
ZSCAN31	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.9767
ATG2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26478
GOSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0652
TCF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98237
Perturb_10638_Mut_Cryaa_SRP104440	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.53229
superficial stratum of FCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33857
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.1319
regulation of cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.327
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.13816
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.886
NGRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85669
SLC35E2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99882
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6913
anterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.986579
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.83591
496100355_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	8.14713
IGDCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46293
GALNT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85786
PARG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10388
EB2	CCLE Cell Line Gene Expression Profiles	1.0	1.62853
H3K27ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SKOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22509
DAZAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63255
GSE163862_2_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Genetic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.541
TCF12	ENCODE Transcription Factor Targets	1.0	null
cerebellar cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.62232
cingulate gyrus, parietal part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.939251
ventral subnucleus of MG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04561
VCPIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92985
JIMT1	CCLE Cell Line Gene CNV Profiles	1.0	1.78472
ZMYM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34683
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.947447
ZNF584	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42517
medial part of the isB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00219
KDM3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19628
ECC12	CCLE Cell Line Gene CNV Profiles	1.0	2.39866
Sarcoma_SARC_TCGA-DX-AB2J-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9385264-NIHMS1828071-supplement-8.xlsx-ESR1-gene_symbol_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE228106_3_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ASXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13293
PAQR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8187
TNFAIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31252
AFMID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33076
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.30023
Perturb_8450_KD_NPM1_SRP230777	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.65043
posteroventral (inferior) parietal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.86705
ZNF664	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47219
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.7996
HYAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.83573
Acute Myeloid Leukemia_LAML_TCGA-AB-2990-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal muscle development	MGI Mouse Phenotype Associations 2023	1.0	null
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.5222
CAVIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13457
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE120370_0_v_3_thrombin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
STT3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85154
Prelimbic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36754
hsa-miR-3130-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
M059K	DepMap CRISPR Gene Dependency	1.0	2.2915
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36965
ZC3H15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86303
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8231
layer 1 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-4.09596
GNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39204
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EU-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A4DS-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MC1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19452
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2711
Ebf4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.9889
Mono-Mac-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.874
DPP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12565
ZMAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05073
r1 part of vestibular nucleus Y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18749
DACT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94563
RPSA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8699
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21892
TP53-23651856-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ARL6IP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53387
layer 2 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.05005
hsa-miR-1252	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
CST6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85033
BMPR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71505
NCBP2AS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5464
GPX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83119
GSE96641_5_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
USP42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16099
decreased skeletal muscle fiber diameter	MGI Mouse Phenotype Associations 2023	1.0	null
PRPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82946
TET1	ChEA Transcription Factor Targets	1.0	null
CA14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99036
Interbrain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19989
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34504
TBX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82766
superficial stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57957
Perturb_10767_KO_Nrf2_SRP311380	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.3174
DCPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64007
Brain stem	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09386
SU-DHL-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.45328
decreased skeletal muscle weight	MGI Mouse Phenotype Associations 2023	1.0	null
STAT3	ENCODE Transcription Factor Targets	1.0	null
MYOG_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39032
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01065
Diabetes Mellitus	DisGeNET Gene-Disease Associations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-K7-AAU7-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autosomal dominant disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.541
ZNF771	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8984
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4642-01B-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RKN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07534
RTN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48882
Gallbladder disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.822
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE232631_5_v_3_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CAPAN2	CCLE Cell Line Gene Expression Profiles	1.0	1.42201
superficial stratum of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.05967
SF3B6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32694
GSE86507,GSE86509_7_v_2_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2522
medial subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10709
GPANK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34049
GSE188599_11_v_10_resolvin e1_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE211286_1_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.26665
Perturb_12081_KO_Stat5_SRP060232	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	18.8539
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22532
GSE210885_3_v_6_klf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GNPTAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64582
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.02
NAAA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45583
Orbital area, medial part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54805
TPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26852
MEGF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71248
GSE122101,GSE122103_3_v_4_ssu72_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TRIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01051
biological regulation	GO Biological Process Annotations 2015	1.0	null
TIMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21922
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.982107
PDIA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78105
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7893
496100515_HIP_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.47442
GSE127970_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
S100A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30582
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NPRL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1109
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Superior olivary complex, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28966
PDS5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78285
ERI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.61342
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5709-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYOD1	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCKAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98288
CXXC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19571
primary auditory cortex (core)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.883316
UGGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99951
hsa-miR-532-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
striatum_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.860733
PRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65048
NCIH650	CCLE Cell Line Gene CNV Profiles	1.0	1.39442
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.01321
FBXO33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06775
Perturb_8136_KD_G3BP2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.75513
basal part of terminal hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04315
Frontal pole, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66085
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.8255
internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057009
GSE110268_0_v_3_foxd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NANP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1239
Lung squamous cell carcinoma_LUSC_TCGA-90-6837-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCDC28B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02859
Brain Lower Grade Glioma_LGG_TCGA-DU-5870-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH889	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59348
S1PR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83103
Sperm flagellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.948
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14944
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8E-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_KO_3T3_ONLY_2084_GENES_MNT	Rummagene Transcription Factor Associations 2026	1.0	null
GSE248045,GSE248046_6_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52724
Schizotypal personality disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.033
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUO-01A-12R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HNT-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.84733
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6022-01A-21R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C15orf40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13896
PARP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58461
KDELR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21423
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01065
GSE147366_1_v_4_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13346
SNU886	CCLE Cell Line Gene Expression Profiles	-1.0	-1.80717
GSE168676_0_v_1_dach1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Post bronchodilator FEV1/FVC ratio	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.530103
TNNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13726
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059471
Intestinal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.02
ABCA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95994
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5113
SLC30A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94244
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.88232
GSE63048_11_v_12_morc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
extracellular region	LOCATE Curated Protein Localization Annotations	1.0	null
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.09869
Taenia tecta, ventral part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43498
HAUS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48106
Taenia tecta, dorsal part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2884
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE118617,GSE118619_0_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34509
ZNF558	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23438
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039257
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.50243
FU97	CCLE Cell Line Gene CNV Profiles	1.0	1.56661
CAL33	CCLE Cell Line Gene Expression Profiles	-1.0	-2.80876
HCC44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19845
Lung squamous cell carcinoma_LUSC_TCGA-43-7657-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral hemisphere of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16786
GSE211286_1_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36626
GSE246195,GSE246305_1_v_0_sin3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
island of Calleja major	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88862
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.83226
extracellular region	GO Cellular Component Annotations 2015	1.0	null
SYT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49345
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50939
episupraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62181
paravermis of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0347
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9641
anterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.76093
VMRCLCD	CCLE Cell Line Gene CNV Profiles	-1.0	-2.57035
HMEL	CCLE Cell Line Gene Expression Profiles	1.0	1.45106
RORB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.81535
POU6F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64516
LLGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41889
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
basal peduncular hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30753
GSE217115_2_v_0_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20595
GNA12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70579
Perturb_10338_KO_Nos3_SRP286435	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.4914
ECC12	COSMIC Cell Line Gene CNV Profiles	1.0	2.30944
Cervix - Ectocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	2.26606
GPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46736
TCCSUP	CCLE Cell Line Gene Expression Profiles	-1.0	-1.81088
GSE95685_2_v_0_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_8189_KD_HNRNPF_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.66173
TP63_01_202	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.15166
H2BC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55219
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A1HT-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11231_KO_Il4_SRP100781	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.74215
Superior colliculus, zonal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.93997
TC205	DepMap CRISPR Gene Dependency	1.0	2.66958
PRR35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4966
limitans nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.900073
FAM219A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17767
ZNF292	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28047
Brain Lower Grade Glioma_LGG_TCGA-DU-A76L-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VDR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73972
Prelimbic area, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.08481
ULBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64885
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.336
HIBADH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83565
PCSK1N	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92717
r7 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21337
Ependymoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.836
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.51109
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.95175
CPNE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56199
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.45408
CYB561	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84918
GSE96641_5_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
central medullary reticular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.50168
UKE-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.89263
periventricular stratum of r7Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27909
SKOV3	DepMap CRISPR Gene Dependency	1.0	2.95697
B3GNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7156
r7 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27782
inner CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.850764
ventrolateral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63374
Primary immunodeficiency disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.02
Entorhinal area, medial part, dorsal zone, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00693
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49263
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KCTD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07083
GSE199899_4_v_2_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SLFN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22435
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
PCYT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17615
SMAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3379
DAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19516
GSE205976,GSE205978_1_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Agranular insular area, ventral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06595
PTPN18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25041
SW1990	DepMap CRISPR Gene Dependency	1.0	2.04624
MRPS17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87542
UBE2Q1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49891
mantle zone of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.26407
HDGFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23265
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5726
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.917668
Brain Lower Grade Glioma_LGG_TCGA-FG-6688-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-SG-A6Z7-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pparg::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.9162
CTAGE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61345
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.91786
LPCAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81917
PRKAB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5792
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.47014
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7059-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.51084
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.055
GID4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47758
NAT14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94211
GSE227891_2_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
periventricular stratum of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00453
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BAIAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18498
ZNF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12538
subcuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.27792
SPOP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61849
SW1417	CCLE Cell Line Gene CNV Profiles	1.0	1.69152
XPNPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81745
HMGN3	ENCODE Transcription Factor Targets	1.0	null
GSE157050,GSE157051_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.4108
P12ICHIKAWA	CCLE Cell Line Gene Expression Profiles	1.0	1.83965
EMC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.6493
TP73	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4787
XBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52227
NCI-H292	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RAD21_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCDIN3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19887
MRPS34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54552
ARFGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4014
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10443
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
URGCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5021
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.093
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.915966
YES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1592
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.917668
HUT102	CCLE Cell Line Gene Expression Profiles	1.0	1.41704
ISL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31339
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039366
superior temporal gyrus, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.863405
Taenia tecta, ventral part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.27136
ZBTB32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50521
superior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00796
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22794
diffuse Z line	MGI Mouse Phenotype Associations 2023	1.0	null
MYOD1_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AAR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26333
TACSTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75208
inferior frontal gyrus, orbital part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.46813
fallopian tube	GTEx Tissue Gene Expression Profiles	1.0	0.864617
UNC13B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74371
GSE248045,GSE248046_6_v_2_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Field CA3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.93546
oculomotor nuclear complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.3967
NDUFV2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73625
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32111
PMC7782476-41467_2020_20434_MOESM7_ESM.xlsx-KLF14_string_interactions-node2_KLF14	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_6440_KD_Pten_SRP280101	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE174383_6_v_5_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mantle zone of r7Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0012
negative regulation of biological process	GO Biological Process Annotations 2015	1.0	null
SLC1A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02413
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29511
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF263	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6273
GSE197564,GSE198513_2_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RPL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65988
CNFN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04028
U251MG	CCLE Cell Line Gene Expression Profiles	-1.0	-1.65699
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5UM-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRKCG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73376
GSE248045,GSE248046_4_v_2_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WT-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USP46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67445
pyramidal layer of taenia tecta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.06068
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCallEPC1-PHF1_H3K27me3_k562-SYMBOL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
anterior olfactory area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.26407
PRKCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49644
medial superior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48967
SRD5A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0587
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_4236_KD_Cnot7_SRP091584	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.91844
CACNG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01472
amygdaloid complex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.85432
temporal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.46505
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.917668
HCC44	DepMap CRISPR Gene Dependency	1.0	2.35939
GSE248045,GSE248046_4_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE244072_10_v_8_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
L3MBTL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2108
B3GALT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22986
FAAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20576
RECQL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64004
KARPAS422	DepMap CRISPR Gene Dependency	1.0	3.7157
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.2346
AJUBA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21144
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Carbohydrate metabolic disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.751
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15496
TXLNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67228
Prostate adenocarcinoma_PRAD_TCGA-CH-5761-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Infralimbic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.53729
HS821T	CCLE Cell Line Gene Expression Profiles	1.0	1.96521
ACHN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.841745
GSE143212_0_v_3_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.02
SLC4A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03133
CHL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FKBP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95318
IZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.42338
FOXJ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82081
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary motor cortex (area M1, area 4)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.994182
ADCY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70764
hsa-miR-4799-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
ZNF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6695
MYOD1_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CLN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27907
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23305
CCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52076
CADO-ES1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.895405
DARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19175
outer CP in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.93944
Brain Lower Grade Glioma_LGG_TCGA-VV-A829-01A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HYLS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30153
Perturb_10984_KO_Fam20a_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.66562
Trachea	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.8526
KCNN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92667
posterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31742
PDPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77849
Type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.296
Perturb_10995_KO_Kmo_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.73196
Kidney Chromophobe_KICH_TCGA-KL-8338-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CMYC-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.838013
cellular_component	GO Cellular Component Annotations 2015	1.0	null
hippocampus (hippocampal formation)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.969403
PANC0504	DepMap CRISPR Gene Dependency	1.0	2.5259
ZNF510	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.71408
TATDN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30294
frontal cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33536
MYOG	ENCODE Transcription Factor Targets	1.0	null
periventricular stratum of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44643
BCL3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.94745
Brain Lower Grade Glioma_LGG_TCGA-HT-8107-01A-13R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE140	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41974
NRBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36633
COV318	CCLE Cell Line Gene Expression Profiles	1.0	1.982
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05049
regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
hsa-miR-150	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3RC-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EP300_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PNRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09139
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.971652
RPS6KA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02518
SLC1A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25456
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052184
TERF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59294
LP-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
r6 part of spinal trigeminal nucleus, pars oralis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16195
hsa-miR-4713-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SOX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5679
GSE222047_0_v_1_imidazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.856351
SUCLG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81079
RWDD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58704
TSPYL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57952
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EVSAT	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5125
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE231648_1_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PPTC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01161
Prostate adenocarcinoma_PRAD_TCGA-HC-7078-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Serine protease inhibitor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.159
CERS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93716
MTF2	ChEA Transcription Factor Targets	1.0	null
gyrus rectus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.915413
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Autoimmune disease of gastrointestinal tract	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.02
occipito-temporal gyrus, left, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01455
dorsolateral prefrontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41154
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A75O-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARMCX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0186
CHPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99921
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AP-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE65617_2_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.5868
HOXC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32344
Acute Myeloid Leukemia_LAML_TCGA-AB-2995-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUP50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85684
QGP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19845
CPHXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63257
pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.236921
PINLYP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70784
MCAS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.947447
Entorhinal area, lateral part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6644
Synaptic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.521
ASPC1	DepMap CRISPR Gene Dependency	1.0	4.60411
superficial stratum of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78729
PIP4K2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.555
INO80C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.44033
UQCRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33537
SEC24A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87207
hippocampus (hippocampal formation)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1649
Perturb_10696_KD_Gls2_SRP326675	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.601
Entorhinal area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34188
DNAJA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.37701
GSE146546,GSE146807_0_v_1_igf2bp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CHKA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67467
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
negative regulation of protein processing	GO Biological Process Annotations 2015	1.0	null
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01576
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01402
DCAF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46887
r10 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32637
ABCD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09711
ATPAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60604
Large_Intestine-goblet cell	Tabula Sapiens Gene-Cell Associations	1.0	0.0
cuneate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.6516
Central amygdalar nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04473
RFX5	ENCODE Transcription Factor Targets	1.0	null
RFX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76958
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.27433
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.72283
Idiopathic fibrosing alveolitis_Lung Tissue_GSE21369	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.60293
ZNF775	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02179
periventricular stratum of r8Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09853
HCC4006	CCLE Cell Line Gene CNV Profiles	-1.0	-2.02502
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r3 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25456
NCBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08643
GSE144231_6_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_11145_KO_1810027O10Rik_ERP013119	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.70342
PDS5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20947
RNASE8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52407
GSE178227_1_v_2_tet1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
METTL14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84721
AGAP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57787
EBLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43944
SHISA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4056
RERF-GC-1B	COSMIC Cell Line Gene CNV Profiles	1.0	2.30944
ZNF668	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85367
basolateral nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.901906
SNU668	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5742
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.573013
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A5UD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COX7C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16364
r4 part of descending trigeminal sensory nucleus, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08636
hippocampus (cortex Ammonis)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47183
pontine raphe nucleus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.940233
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18945
GSE158197_6_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VASN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60564
Esophagus - Mucosa	GTEx Tissue Gene Expression Profiles 2023	1.0	3.71419
PDCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30067
HCT15	DepMap CRISPR Gene Dependency	1.0	2.42104
OPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53061
PTPN14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36695
SPPL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21376
NCI-H2085	COSMIC Cell Line Gene CNV Profiles	1.0	2.30944
regulation of protein metabolic process	GO Biological Process Annotations 2015	1.0	null
HS 69ST	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47352
INTS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33066
CTCF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF215	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18187
G401	CCLE Cell Line Gene Expression Profiles	1.0	1.59215
ATG12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76663
hsa-miR-4482	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
LMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65476
r7 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03589
Perturb_3958_KO_GSDMB_SRP350967	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.43857
TET1-21490601-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
496100578_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.79394
GSE157777_2_v_3_foxa3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PCNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34011
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03837
hsa-miR-4653-5p	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.44516
LXF-289	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3471-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DNAAF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93347
superficial stratum of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06034
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44R-06A-41R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Paraflocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09923
HDAC2	ENCODE Transcription Factor Targets	1.0	null
HEL9217	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57169
ZGPAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37265
TSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02604
intermediate stratum of r10BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25896
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8225
forebrain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16344
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.834077
MIER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92521
PKN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66674
GSE193541_0_v_3_nifurtimox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H1155	COSMIC Cell Line Gene Mutation Profiles	1.0	null
1321N1	CCLE Cell Line Gene CNV Profiles	1.0	1.39049
RCCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12788
CORL279	CCLE Cell Line Gene Expression Profiles	-1.0	-1.81191
TRIM54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7385
Anterior cingulate area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51857
BL1097 (DYRK3)	NURSA Protein Complexes	1.0	null
SCPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32212
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE144443_0_v_6_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-7966-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF680	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46246
BRICD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04569
TIMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66638
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06796
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06861
SYT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60114
GSE217378_2_v_0_lin28b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SNU685	CCLE Cell Line Gene Expression Profiles	-1.0	-1.92686
NKX3-2	JASPAR Predicted Transcription Factor Targets	1.0	null
PIAS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00057
ENTPD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22295
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WH-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE244072_10_v_9_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bed nuclei of the stria terminalis, anterior division, anterolateral area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06256
navicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.12789
GSE232631_4_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AOB, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57957
MCFD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82258
KHM1B	CCLE Cell Line Gene Expression Profiles	1.0	2.18214
SP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.26686
superficial stratum of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.26407
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.218
GSE202175_1_v_2_triptolide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QH-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.850905
diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.218034
carbohydrate metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.188938
Perturb_10818_KO_Xbp1_SRP197108	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.4658
OccipitalLobe	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.05695
Perturb_8132_KD_EIF4A3_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.05006
KYSE-520	COSMIC Cell Line Gene CNV Profiles	1.0	2.30944
SEC31A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23271
GMIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88218
QDPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49538
cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042864
MROH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87035
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39877
SOCS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8597
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8042-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LMX1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46887
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.878412
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77434
GSE217694_3_v_2_pold1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.25371
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.902896
GSE193541_1_v_2_nifurtimox_human	RummaGEO Drug Perturbation Signatures	1.0	null
Inflammatory bowel disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.02
ZNF524	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08161
GSE226316_11_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
neural plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23467
Perturb_10278_KO_Fam151a_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.73093
LRCH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26642
EPOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96372
Uterine Carcinosarcoma_UCS_TCGA-N9-A4PZ-01A-22R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r7 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06034
inner CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.918992
r6 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44588
Kidney renal papillary cell carcinoma_KIRP_TCGA-KV-A74V-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCAF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93853
IRX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34185
UCKL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16391
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4157
TMEM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66486
periventricular stratum of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02436
ANAPC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03596
Superior colliculus, superficial gray layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03822
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A6UG-01A-32R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VPS9D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75877
cingulate gyrus, retrosplenial part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.922557
SP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.982002
GSE207471_2_v_3_btla_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE168797_1_v_6_cannabidiol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.095
GNRH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66869
APP	Pathway Commons Protein-Protein Interactions	1.0	null
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4772
EP300_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A7EI-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE103372_1_v_2_smad1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PHLPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8616
GFUS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30239
GSE153137,GSE153140_2_v_0_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
external part of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49561
Cysteine-rich  secretory protein, allergen V5/Tpx-1-related	InterPro Predicted Protein Domain Annotations	1.0	null
MOV10L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45992
Acute Myeloid Leukemia_LAML_TCGA-AB-2917-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Exocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.518
GSE200673,GSE200691_1_v_3_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61661
EPS8L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03443
YEATS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36007
HCN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12832
GSE165122_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Dermal dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.744
NLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63227
RAB31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74313
STBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78429
SP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.964925
GSE143743_0_v_2_c9orf72_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158743_1_v_2_nfkbia_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.003
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.9908
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HDLM2	CCLE Cell Line Gene CNV Profiles	-1.0	-2.21779
Perturb_10982_KO_Fads1_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.43775
COL9A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07272
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.274
PDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56251
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.02
E2F1-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14944
SR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.97673
extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.185469
ERVK3-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50502
pyramidal layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14257
CDX2	ChEA Transcription Factor Targets	1.0	null
hsa-miR-3921	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A5DX-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8299-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00128
endopiriform nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.926723
HCC15	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7584
GSE76771_2_v_3_atf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IER5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0834
ZNF362	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46028
pedunculo(pontine) tegmental  nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.841273
MARK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04578
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.72517
GSE228125_2_v_1_ptafr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AOB, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24943
molecular function regulator	GO Molecular Function Annotations 2015	1.0	null
enzyme inhibitor activity	GO Molecular Function Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-5425-01A-02R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KDM4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37368
TNFRSF12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19199
PIP5KL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00767
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45689
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
layer 2 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30753
GSE157050,GSE157051_2_v_4_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE164757,GSE164759_4_v_3_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.883857
Perturb_14758_KD_LATS1/LATS2_SRP345234	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.49369
Perturb_10272_KO_Fxr_SRP343112	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.05435
PIGH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60558
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A871-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
frontal pole, right, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.828682
PMC11502753-41467_2024_53330_MOESM11_ESM.xlsx-Sheet1-SMAD3_target_genes_A549_SMAD3	Rummagene Transcription Factor Associations 2026	1.0	null
THOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11415
Uterine Carcinosarcoma_UCS_TCGA-N6-A4V9-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TFAP2A	JASPAR Predicted Transcription Factor Targets	1.0	null
AM38	CCLE Cell Line Gene Expression Profiles	-1.0	-1.93087
SNU-61	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TE8	CCLE Cell Line Gene CNV Profiles	1.0	1.78023
RNF115	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37104
disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046879
hsa-miR-4633-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29237
MTF2-20144788-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
HCC44	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41654
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.13503
Fundus of striatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12139
SULF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89262
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7591-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_8060_KO_TP53_SRP182675	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.403
interstitial nucleus of the posterior limb of the anterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50294
GSE244072_10_v_1_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2857-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
maturity-onset diabetes of the young type 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.11
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
CRLF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68542
Zona reticulata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.144
OCILY10	CCLE Cell Line Gene Expression Profiles	1.0	2.22458
P4HTM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40196
ZNF530	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	86.0698
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039725
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A729-06A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Field CA2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03586
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.68418
PLCD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27922
pallium	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35145
SH3BP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26681
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3WX-01A-22R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.974716
GSE118617,GSE118619_2_v_3_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE244072_2_v_1_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8476
amygdaloid complex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.848925
ZNF569	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59402
pineal gland	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.34584
Spinal nucleus of the trigeminal, oral part, middle dorsomedial part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00331
HS766T	COSMIC Cell Line Gene CNV Profiles	1.0	2.30944
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8872
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E6-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KCNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35208
HCT-116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
SP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06998
QGP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44296
GCHFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35845
superior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.71554
planum temporale, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08045
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.9772
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRAK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51212
MACROH2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45983
Anterior cingulate area, ventral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88205
hsa-miR-4755-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
maturity-onset diabetes of the young type 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40684
Hypothalamic medial zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12546
TAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01718
ZNF574	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.9306
BCKDK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82006
CITED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38144
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.36787
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-589	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
MPRIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38063
hsa-miR-1273f	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
negative regulation of hydrolase activity	GO Biological Process Annotations 2015	1.0	null
MAJIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71959
UQCC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77618
GSE144838_1_v_5_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17694
GTF2H3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4971
outer CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02612
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24387
GSE208254_3_v_5_irf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MOLM6	CCLE Cell Line Gene CNV Profiles	-1.0	-2.84839
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TO175T	CCLE Cell Line Gene Expression Profiles	-1.0	-2.21761
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04689
TRAF3IP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57659
IZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.44044
ZNF202	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47465
ECH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24605
ZNF253	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75306
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24387
PROM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26903
PIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75782
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09335
SNU1544	DepMap CRISPR Gene Dependency	1.0	4.44404
Brain Lower Grade Glioma_LGG_TCGA-DB-A75K-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BHLHA15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53303
Taenia tecta, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.0431
MVD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40365
regulation of molecular function	GO Biological Process Annotations 2015	1.0	null
ZIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13596
GSE190681_1_v_0_rtcb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TMEM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2618