association	dataset	threshold value	standardized value
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMO	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00699146
BRD-K32862555_NCGC00183412-01_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
single-organism membrane organization	GO Biological Process Annotations 2015	1.0	null
BCL3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00915853
REST_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RUSQ-0126-SM-47JWV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1203
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40752
GSE192689_0_v_2_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
mitoxantrone-6755	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NB5	DepMap CRISPR Gene Dependency	1.0	2.03819
cephaeline-2429	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.050587
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.66355
Rectum adenocarcinoma_READ_TCGA-EI-6509-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hepatobiliary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.153
SRY-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-U4B1-0826-SM-4DXTW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872864
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.882847
BRD-K12853587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03922
hsa-miR-1200	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
TTI1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K17395396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.6799
NANOG-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA3-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNT-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0476
HDAC2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HT29	CCLE Cell Line Gene Expression Profiles	1.0	1.54707
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.872916
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3721
COPZ1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-NFK9-0226-SM-2HMKQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.88188
TRAPPC4	Pathway Commons Protein-Protein Interactions	1.0	null
EOMES-21245162-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_1210_KO_Zbtb7a/Sp1_SRP302435	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.55319
GSE96991,GSE97117_5_v_1_il11_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
internal granular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17308
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04956
PMC7818749-12931_2021_1617_MOESM1_ESM.xlsx-TBX4-ENSEMBL_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
cellular chemical homeostasis	GO Biological Process Annotations 2015	1.0	null
GSE226983_2_v_0_ddx5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146156_2_v_3_tagap_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04956
SUZ12-18974828-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
HOOK1	Pathway Commons Protein-Protein Interactions	1.0	null
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.332812
ahr_19454665_epidermal_langerhans_cell_lof_mouse_gpl339_gds3575	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.049164
H3K27ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
phagocytic vesicle membrane	GO Cellular Component Annotations 2015	1.0	null
Bed nuclei of the stria terminalis, anterior division, fusiform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43318
BRD-K07482874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31672
NLRC5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00582659
orbital frontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29554
centromedian nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.875384
GJB3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00472704
BRD-K29039402	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58921
Sarcoma_SARC_TCGA-3B-A9HO-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-E2A_Pre-Pro-B-Cells_ChIP-seq_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
Heschl's gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.859022
GTEX-QV31-0126-SM-447BP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09046
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13646
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anterior cingulate area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.69606
r8 part of the paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.87069
mRNA_ASCL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
SIMA	GDSC Cell Line Gene Expression Profiles	-1.0	-1.43031
ARHGEF1	Pathway Commons Protein-Protein Interactions	1.0	null
AB-33-EM56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.264361
CSNK1D	Pathway Commons Protein-Protein Interactions	1.0	null
HUT102	CCLE Cell Line Gene Expression Profiles	-1.0	-1.72707
FBN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00462298
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052005
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8707
BRCA1	ENCODE Transcription Factor Targets	1.0	null
GSE188570,GSE188571_3_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TSC1	Pathway Commons Protein-Protein Interactions	1.0	null
Learning Disorders	CTD Gene-Disease Associations	1.0	1.22821
CA46	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44496
H4K91ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
furan	CTD Gene-Chemical Interactions	1.0	null
vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.254017
Perturb_5861_KD_H3f3a_SRP133189	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.52696
GTEX-VJYA-0126-SM-4KL1P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38709
Brain - Caudate (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.75817
Adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.248
BRD-K73838513_S1260_SKB_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
uterus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070369
BRD-K21680192_mitoxantrone_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A5R5-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.911645
Pancreatic Neoplasms	CTD Gene-Disease Associations	1.0	1.15967
BRD-K47409867	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34136
mRNA_MYC_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me1_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K35788497	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82634
NRAS	Pathway Commons Protein-Protein Interactions	1.0	null
PRPF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01676
ANPEP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00716844
VMRCRCW	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36043
Pancreatic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.397
GSE149903_3_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.12554
H3K27me3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IM-95M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42154
GTEX-R55E-1326-SM-48FCR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08706
REST_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PW2O-0226-SM-48TC7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6755
BRD-A19037878_trichostatin A_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FD-91-OK66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.362311
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-51-4081-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
QGP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.929964
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-OHPL-0526-SM-3NM8U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914856
CRCGN013_HEPG2_24H:I02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00399
PMC7902901-Table_12.xlsx-CREB1-Unnamed_7_CREB1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QEG5-1126-SM-33HC2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5408
Carcinoma, Hepatocellular_Hepatic Tissue_GSE2127	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.11169
USF2_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A3M2-01A-21R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KDM2B-26808549-CHIP-SEQ-REH-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
APOLD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00707789
GSE199092_2_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	1.0	null
KDM2B-26808549-CHIP-SEQ-SUP-B15-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RFX5	ENCODE Transcription Factor Targets	1.0	null
pancreatic carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.331756
H3K9ac_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE144484_2_v_3_mllt6_human	RummaGEO Gene Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.971401
SNX13	Pathway Commons Protein-Protein Interactions	1.0	null
PMC6113333-41598_2018_31192_MOESM11_ESM.xlsx-Sheet1-H1_NFIC_NFIC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE203158_0_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE248858_5_v_2_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF740	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	159.18
MCF7_Belinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0102352
superficial stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67374
Testis	GTEx Tissue Gene Expression Profiles 2023	1.0	1.11499
GSE213588_8_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NIPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55788
GTEX-NPJ7-2826-SM-2I3FU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.829271
URGCP	Pathway Commons Protein-Protein Interactions	1.0	null
OXSR1	Pathway Commons Protein-Protein Interactions	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.51751
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
protein transport	GO Biological Process Annotations 2023	1.0	null
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	2.14202
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07906
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.876409
KLHDC7B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00578225
CRCGN016_MCF10A.WT.HP_24H:D19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.30432
EP300_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUZ12-16625203-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
spinal cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060114
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7590-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF1_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNX17	Pathway Commons Protein-Protein Interactions	1.0	null
KDM5B	ENCODE Transcription Factor Targets	1.0	null
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
PRKDC	Pathway Commons Protein-Protein Interactions	1.0	null
BD-96-HO33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.956881
Spinal nucleus of the trigeminal, oral part, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38804
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-5872-02A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K61717269_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CEP72	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00691833
skin_5e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.07165
Pancreatic carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.427
SMARCA4-20176728-TSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A15330900	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56726
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ANKFY1	Pathway Commons Protein-Protein Interactions	1.0	null
GE-98-ZI68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.365903
PMC3526425-1471-2164-13-572-S3.xlsx-STAT6-STAT6_STAT6	Rummagene Transcription Factor Associations 2026	1.0	null
CHRD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57401
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	GO Molecular Function Annotations 2015	1.0	null
intracellular	GeneRIF Biological Term Annotations	1.0	null
GSE211983_1_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SUP-M2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
Prelimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80569
Epithelial cell_Lung_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
CRCGN015_HEPG2_48H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.772
Neurobehavioral Manifestations	CTD Gene-Disease Associations	1.0	1.2895
CBR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0047467
GTEX-PLZ6-1526-SM-2S1OC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28548
layer 4 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35772
ARHGAP1	Pathway Commons Protein-Protein Interactions	1.0	null
ACHE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00451098
GSE169152_5_v_2_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K95927760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11734
arterial stenosis	GWASdb SNP-Phenotype Associations	1.0	0.208995
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062404
SG in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.956629
Orbital area, medial part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02227
COG3	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62716
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.699
layer 3 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04172
Adenoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.7
PMC6412103-mmc1.docx-5-M00695_ETF_P_8_350E-5_N_428_31_5_2_TEAD2	Rummagene Transcription Factor Associations 2026	1.0	null
GLTP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00626763
GSE245134_2_v_3_atg5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08561
BD-49-MD69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.737588
GTEX-S3XE-0626-SM-4AD6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91579
PPIF_KO_GSE23028_45_mouse_heart (8 wk)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
mRNA_POU5F1_16518401	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Perturb_1197_KO_Klf13_SRP302435	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.59861
EE-03-SG02_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.351824
BRD-K44344720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47748
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4861-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BRD-K27256143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72032
GSE69869_0_v_1_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
supraoptic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.45558
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78K-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPI1-23127762-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-RM2N-0426-SM-2TF4T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84109
GSE48812_9_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CALR	Pathway Commons Protein-Protein Interactions	1.0	null
abnormality of forebrain morphology	GWASdb SNP-Phenotype Associations	1.0	0.232717
Thalamus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.06809
NCIH1963	CCLE Cell Line Gene CNV Profiles	1.0	1.44982
GSE140092_0_v_1_socs3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K58772419_AZD-6482_BT20_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE179974_3_v_2_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9894241-pnas.2211429119.sd05.xlsx-G1_REST-Dataset_S5_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
KA-81-AG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.535009
GTEX-O5YT-0926-SM-48TDG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19933
GTEX-REY6-0726-SM-2TF4M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05672
H4 neuroglioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.706
protein localization	GO Biological Process Annotations 2023	1.0	null
GSE185519_4_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9288051-13046_2022_2428_MOESM4_ESM.xlsx-Super_enhancers_in_AML2-OVERLAP_GENES_RUNX3	Rummagene Transcription Factor Associations 2026	1.0	null
GJB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00677648
GSE135705_5_v_3_corticosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2057
homochlorcyclizine-7295	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Postpiriform transition area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57024
tobacco use disorder	GAD Gene-Disease Associations	1.0	null
BRD-K86817746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.877
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K27991961	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1211
AP2A1	Pathway Commons Protein-Protein Interactions	1.0	null
Apical cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.164
HLE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40175
organelle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.067081
BRD-A37645929	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55484
GSE223008_6_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mantle zone of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15454
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pcgf2_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.588761
BRD-K44432556_VU0418946-2_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE148066,GSE157787_0_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.206082
NAMALWA	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:K22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1129
PMC12513837-41588_2025_2336_MOESM4_ESM.xlsx-Supplementary_Table_1-Supplementary_Table_1_List_of_AR-only_and_p300_AR-shared_enhancer_regulated_genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R53T-1126-SM-48FD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826464
GSE214823,GSE214824_4_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12978397-wjon-17-02-247-s002.xlsx-S2-Suppl_2_Two-sample_MR_analysis_of_blood_eQTLs_associated_with_LUAD_P_0_05_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.8503
supragenual nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23771
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.21124
intracellular protein transport	GO Biological Process Annotations 2025	1.0	null
UBF1/2-26484160-CHIP-SEQ-HMECS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE107505_3_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2795
GTEX-QV44-2026-SM-2S1RD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17014
Brain Lower Grade Glioma_LGG_TCGA-HT-7882-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE168587,GSE168752_3_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE203158_0_v_13_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CEBPD	ENCODE Transcription Factor Targets	1.0	null
GTEX-RU72-0726-SM-46MUW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.990724
EGR1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
3291_GATA1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.791519
MCF7_MLN8054_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0136182
SPI1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF7-22412390-EML-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3OO-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.93579
BRD-K18562847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2724
BRD-K20171002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29224
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ASPA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00530183
BCLAF1	ENCODE Transcription Factor Targets	1.0	null
GMNN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00529619
ZNF281	ChEA Transcription Factor Targets	1.0	null
IZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27957
BRD-K42805893_HG-14-8-02_HCC515_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE120336_0_v_2_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K44193634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07304
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E16_vs_D1_1084_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06416
TAF1_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DLD1	BioGPS Cell Line Gene Expression Profiles	1.0	0.89213
HL60	BioGPS Cell Line Gene Expression Profiles	1.0	1.22862
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE131887_5_v_2_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
WASH2P	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.70201
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49973
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.97073
18794137-SuppTable1e	GeneSigDB Published Gene Signatures	1.0	null
GSE221020,GSE221023_2_v_1_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ERBB3	Pathway Commons Protein-Protein Interactions	1.0	null
957_C11ORF74_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.919715
PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-NT_Fig1c-Gene_Symbol_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P44H-0426-SM-2XCEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860076
carbamoyl-phosphate synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.805
CEBPB_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Neoplasm Metastasis	CTD Gene-Disease Associations	1.0	1.38298
TCCSUP	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF141	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00714759
PMC6344081-elife-40364-supp8.xlsx-PLZF-Si-diff-expressed-gen-Down-Symbol_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OIZI-0626-SM-2XCEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63973
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5F-Up_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Abemaciclib_HT-29	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0274956
BTBD18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06489
labetalol-1550	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GCKR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00618751
BC-09-JG96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210989
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AH-1926-SM-2S1PN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03332
OAS3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00597711
CRCGN015_HEPG2_48H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.70067
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RNPEP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00445684
GTEX-QVJO-0011-R10A-SM-2S1QJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07192
BRD-K38947493	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39478
GTEX-X62O-2226-SM-46MW3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07175
BRD-K21284411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56134
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
GSE152441,GSE152442_0_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.0029
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.266
RALA	Pathway Commons Protein-Protein Interactions	1.0	null
SH3GLB1	Pathway Commons Protein-Protein Interactions	1.0	null
SNAI2_01_225	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59528
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE149075_3_v_5_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H6PD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00542759
STAT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00729755
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CA6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0062929
TNK1	Pathway Commons Protein-Protein Interactions	1.0	null
DIAPH1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE163240_3_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NANOG-21062744-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Crus 1, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52256
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	1.0	3.44505
GSE134375_0_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
stratum pyramidale of rostral CA3	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.859913
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39013
SNUC1	CCLE Cell Line Gene Expression Profiles	1.0	1.353
Perturb_14443_KO_Mtor_SRP106322	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.17857
TCEANC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22563
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42142
Lung squamous cell carcinoma_LUSC_TCGA-58-8386-11A-01R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K89967940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07296
ascites	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.468048
microglial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.621831
Bed nuclei of the stria terminalis, anterior division, anterolateral area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.2247
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.29753
TTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19351
LSM7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00818522
hsa-miR-27a	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4900-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE235390_4_v_2_lurbinectedin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-381	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GBF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00642882
BA-56-QV45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.572038
BRD-K64353626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94002
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.177301
GSE111138,GSE111149_1_v_0_runx3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.36883
SP4	ENCODE Transcription Factor Targets	1.0	null
interstitial nucleus of Cajal, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.3812
PMC11336098-41598_2024_70235_MOESM1_ESM.pdf-30-PAX9_PAX9	Rummagene Transcription Factor Associations 2026	1.0	null
MMACHC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00588351
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.19371
GM2A	Pathway Commons Protein-Protein Interactions	1.0	null
ChIP_RNF2_16625203	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
HIV_Infected-mDC_None_GSE42058	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.6127
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
FAM13A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00594249
BCAP31	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K06678077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96882
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE184902_3_v_0_adipor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WC-33-YP46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.270038
BRD-K87909389_alvocidib_SKBR3_3_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2872-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Otx2_KO_GDS4440_143_mouse_fourth ventricular choroid plexus tissue	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE149903_3_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K56107062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14454
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04418
BRD-K41859756_-666_HT29_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ARFRP1	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDK19_knockdown_148_GSE32108	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.48326
PMC7220941-41598_2020_64431_MOESM2_ESM.xlsx-WS1_2019_Affy_IDs_RA-STvsOA-ST-Unnamed_2_PAX3	Rummagene Transcription Factor Associations 2026	1.0	null
eed_20123906_mouse_embryonic_stem_cell_lof_mouse_gpl1261_gse19076	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.080606
BRD-K06399794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20173
BRD-A13122391_16-HYDROXYTRIPTOLIDE_HT29_6.0_h_0.08_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MLPH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00603965
Small_Intestine	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.992274
BRD-K21680192_mitoxantrone_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
gonad	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
TBP_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YN-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39X-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4735-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:B20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.13556
C1orf131	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2593
GSE190316,GSE190324_10_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE176008_4_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
cingulate gyrus, retrosplenial part, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14288
15474998-tableS1c	GeneSigDB Published Gene Signatures	1.0	null
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.871468
PA-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ChIP_NANOG_18347094	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
LGE-VZ border region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.834035
PMC11696420-41467_2024_55617_MOESM3_ESM.xlsx-Sheet1-Supplementary_Data_1_The_2495_differentially_expressed_genes_between_the_L3MBTL3_knockout_L3-KO4_or_L3-KO5_and_control_C_groups_of_SUM159PT_cells_L3MBTL3	Rummagene Transcription Factor Associations 2026	1.0	null
HDAC6	ENCODE Transcription Factor Targets	1.0	null
abnormality of the coronary arteries	GWASdb SNP-Phenotype Associations	1.0	0.265819
SLC6A11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00586487
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.132
GSE96641_3_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.47457
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.671
rectum	HPA Tissue Protein Expression Profiles	1.0	0.78613
POLR2A_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Wt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	80.9531
superficial stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36892
cellular process	GO Biological Process Annotations 2015	1.0	null
3457_GOLGA3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.557633
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE216274,GSE216292_4_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ARFGEF1	Pathway Commons Protein-Protein Interactions	1.0	null
CEBPB-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE160246_9_v_1_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
FOXA1-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BSG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00564097
KDM1A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW1463	CCLE Cell Line Gene Expression Profiles	1.0	1.77782
HS571T	CCLE Cell Line Gene CNV Profiles	-1.0	-2.0576
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SEPT11	Pathway Commons Protein-Protein Interactions	1.0	null
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.26982
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K83942575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74091
GSE152441,GSE152442_0_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-UJMC-1826-SM-3GADT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12737
YES1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00461115
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE247764_1_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT5A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K25165359	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40562
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WEY5-1326-SM-3GILS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896372
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
central part of CEl	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.881968
mRNA_POU5F1_16767105	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K02708799_GSK-1059615_HEPG2_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
dorsolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.53865
SMAD3-21741376-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZFP281-27345836-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ChIP_MTF2_20144788	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
peripheral portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.862157
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.26887
BRD-K76976010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04865
FCRL6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00414363
GSE216273,GSE216292_0_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hemorrhage	CTD Gene-Disease Associations	1.0	1.48196
Endoplasmic reticulum-Golgi intermediate compartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.01
GSE186810,GSE186813_7_v_5_furin_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF460	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	119.602
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
striatum_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.46753
PRKD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00494687
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.9566
BRD-K76401790_JNK-IN-5A_PC3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
organelle	GO Cellular Component Annotations 2015	1.0	null
SOX2-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SEPT7	Pathway Commons Protein-Protein Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2J6-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dementia	GWASdb SNP-Disease Associations	1.0	0.339425
Sarcoma_SARC_TCGA-DX-A2J4-01A-32R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2062
RAB7A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Paragigantocellular reticular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08897
cellular component organization	GO Biological Process Annotations 2015	1.0	null
posteroventral (inferior) parietal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03835
GREB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00118
PHF8	ENCODE Transcription Factor Targets	1.0	null
JUND_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF2	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Ruffle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.037
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
XPO4	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K36054906	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41406
SP in entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04086
EMX2_Deficiency_GDS3173_607_mouse_Embryonic urogenital epithelium - day 10.5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
WDFY3	Pathway Commons Protein-Protein Interactions	1.0	null
SNRK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00576163
GSE118794_2_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EGFR	Pathway Commons Protein-Protein Interactions	1.0	null
anterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.916245
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49496
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FIG4	Pathway Commons Protein-Protein Interactions	1.0	null
GSE150669_2_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SLC2A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00460873
organic cyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
TIMD4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0068307
Intestinal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.946
GTEX-S4UY-0006-SM-3K2A7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82907
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
transcription	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K78252315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06436
BRD-K64173373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71504
phagocytic vesicle	GO Cellular Component Annotations 2023	1.0	null
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16249
skin_5f	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.19069
STIM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00724996
BRD-K45092891	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5541
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.94762
PARVG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0041097
Temporal association areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41987
GSE186287_1_v_3_ufm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.82463
Edema	CTD Gene-Disease Associations	1.0	1.74641
GSE169152_5_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
GTEX-X4EP-0011-R2B-SM-3P625	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45783
primary motor cortex (area M1, area 4)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19469
t70-white-adipose_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.70694
ZNF343	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	82.2836
POLR2A_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVN-0826-SM-48TZ2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07269
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.984396
Simple lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11082
Mesothelioma_MESO_TCGA-TS-A7PB-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCallEPC1-PHF1_H3K27me3_k562-SYMBOL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16594
PLIN3	Pathway Commons Protein-Protein Interactions	1.0	null
ticlopidine-1975	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SARS-CoV MA15_Day4-C57BL6_None_GSE51386	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.49866
NUDC	Pathway Commons Protein-Protein Interactions	1.0	null
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.35286
wi26va4	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.854
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN010_HEPG2_24H:A08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0467
ELL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00513233
HDAC2_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMED1	Pathway Commons Protein-Protein Interactions	1.0	null
associates	GeneRIF Biological Term Annotations	1.0	null
GTEX-R55G-0226-SM-48FEI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08739
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4859-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.97191
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.72331
cytoplasmic vesicle part	GO Cellular Component Annotations 2015	1.0	null
cytoplasmic vesicle	GO Cellular Component Annotations 2015	1.0	null
7441_RPL17_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.506372
PSTPIP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00703356
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-N7MT-1226-SM-2D7W4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19085
GSE159678_4_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAFK_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VPS52	Pathway Commons Protein-Protein Interactions	1.0	null
medial amygdala, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07498
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.955133
SMAD4-21741376-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE182179_0_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GIMAP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00596905
TAF7	ENCODE Transcription Factor Targets	1.0	null
GTEX-X4EP-0526-SM-3P5YW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882913
GSE147626_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CAOV4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41577
ChIP_SUZ12_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
SLC45A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00439123
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.50425
CD-16-KY17_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.311886
H3K27ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SMC3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K93176491	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70579
RAB3GAP2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE163240_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ELF5	JASPAR Predicted Transcription Factor Targets	1.0	null
VRK1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K78431006_crizotinib_HEPG2_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE115363_3_v_5_esrrb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
paraterete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36948
SKNO1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.38818
superficial stratum of r7Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13125
MGE-Lateral region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17122
GSE219103,GSE219104_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
WSU-FSCCL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.972102
BRD-A43126523_NCGC00183690-01_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE213588_8_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SBDS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00627493
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3BZ-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.52217
amygdaloid complex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.855111
gtp binding	GO Molecular Function Annotations 2015	1.0	null
GSE214583,GSE214585_1_v_0_steap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12703482-AMS-21-5-213605-s2.xlsx-Supplementary_Table_SXV-SMR_results_of_expression_levels_of_VDR_target_genes_in_peripheral_blood_and_risk_of_hepatocellular_carcinoma_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF-21964334-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
EPB41L2	Pathway Commons Protein-Protein Interactions	1.0	null
branch	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.10225
GSE144120_3_v_1_plcg2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
COLO 205	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40532
Perturb_17598_KO_St2_SRP247658	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.6409
PC-87-OG75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.242334
BRD-K37285826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19325
PTPA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00676493
STC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0048373
Uterine Cervical Neoplasms	CTD Gene-Disease Associations	1.0	1.41911
globose nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03175
POLM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2952
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.988505
HAX1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K20368781	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.54296
PMC4731966-13195_2015_167_MOESM9_ESM.xlsx-SEKI_LPS_Up-Unnamed_3_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
ABR	Pathway Commons Protein-Protein Interactions	1.0	null
superior temporal gyrus, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.843551
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A1HT-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KCNE1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00773032
EZH2	ENCODE Transcription Factor Targets	1.0	null
chr13_110471908_G_A_b38	GTEx eQTL 2025	1.0	1.40575
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66247
COL26A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87075
SH3BP1	Pathway Commons Protein-Protein Interactions	1.0	null
inferolateral temporal cortex (area TEv, area 20)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13296
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-D1-D3_643_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE44157,GSE44163_1_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TPD52L3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00617324
tdif1	GeneRIF Biological Term Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5176-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TN2	DepMap CRISPR Gene Dependency	1.0	7.15253
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CF-65-GU65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.206501
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BT-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UTHO-2926-SM-3P5Z9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04993
Monocyte_Fetal kidney_Human	CellMarker Gene-Cell Type Associations	1.0	null
GTEX-RU72-0011-R5A-SM-2TF6U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26988
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24091
PPT1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE152441,GSE152442_6_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Type IV secretion system complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.809
SUZ12-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE71491_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K44403120	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19657
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
fluphenazine-1178	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FA-63-WI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.638095
BRD-K58644442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0303
GTEX-XMD1-0011-R11A-SM-4AT5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23452
RAC1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K99532291_SPB02303_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN010_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.51203
Weight Gain	CTD Gene-Disease Associations	1.0	1.3736
Acute Myeloid Leukemia_LAML_TCGA-AB-2803-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.97074
BRD-A35588707_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN017_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.14847
COG5	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K92317137_-666_NOMO1_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	3.24385
GSE188870,GSE188871_0_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146962_0_v_1_glucosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
DGKQ	Pathway Commons Protein-Protein Interactions	1.0	null
CEBPB-21427703-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SACM1L	Pathway Commons Protein-Protein Interactions	1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-OXRK-1826-SM-2HMJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10292
BRD-K64890080_BI-2536_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_10196_KD_FCircAE_SRP180885	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
MDAMB175VII	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.644399
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE205963_0_v_1_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7902901-Table_12.xlsx-PAX5-Unnamed_7_PAX5	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.911645
CDC42BPG	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K78126613_-666_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MED9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60769
CDK11A	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ARID3A	ENCODE Transcription Factor Targets	1.0	null
TIGAR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00530979
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Laticifer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.49
EFEMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24117
ZFX_KO_GDS2718_151_mouse_hematopoietic stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NPR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00572717
GTEX-XMK1-2526-SM-4B666	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43648
STAT3	Pathway Commons Protein-Protein Interactions	1.0	null
OSBP	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-3194-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Perturb_17217_KD_NANOG_ERP128142	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
STAT1	ENCODE Transcription Factor Targets	1.0	null
BRD-K40332193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44927
orbital frontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.29657
CD83	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00662543
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13597
GTEX-XXEK-0326-SM-4BRVV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832054
adiphenine-7279	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.57458
Uterus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.44281
GTEX-R55E-0011-R6A-SM-2TC5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.871589
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Bladder-macrophage	Tabula Sapiens Gene-Cell Associations	1.0	5.49726
GTEX-WHPG-2226-SM-3NMBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04528
GSE157555,GSE157556_4_v_7_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K08408085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.37091
brain	HPA Tissue Gene Expression Profiles	-1.0	-0.882732
uroepithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.319134
GSE217541,GSE217543_3_v_2_tet1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149943_2_v_0_cd8a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CASK	Pathway Commons Protein-Protein Interactions	1.0	null
LIG4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00680891
adrenal_4d	HPA Tissue Sample Gene Expression Profiles	1.0	1.40833
GSE226259_0_v_1_scd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
REST_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
small molecule binding	GO Molecular Function Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-7525-01A-31R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-IZ-A6M9-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Colorectal adenoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.946
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37428
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_24hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.906903
IFT25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13668
icSARS CoV_12Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.45776
GSE127790_10_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Laryngeal tuberculosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.213
CRCGN009_HEPG2_24H:L07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.8354
BRD-K57786075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02638
BRD-K47143916	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59116
GSE48812_9_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
TAF7_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FEZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30691
KDM4C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00475316
ARL2	Pathway Commons Protein-Protein Interactions	1.0	null
cervical adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.134081
ZFP14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.1441
H4K20me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.00791
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20544
SH2D3A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE242083,GSE242098_3_v_1_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE125219,GSE125221_4_v_8_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
5485_NBR1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.760091
BRD-K61717269_-666_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ADCK5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00628344
bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.721465
HIF1A_01_87	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61588
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-T6MN-0126-SM-32PLP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1628
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19252
SPATS2L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00580835
RRAS2	Pathway Commons Protein-Protein Interactions	1.0	null
SEL1L	Pathway Commons Protein-Protein Interactions	1.0	null
COLO 206F	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01245
GSE223008_9_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HDAC6_KO_GDS4375_532_mouse_Foxp3(+) Tregs	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE216538_0_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K30707190_PNU 74654_PL21_6.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Neurotoxicity Syndromes	CTD Gene-Disease Associations	1.0	1.3699
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE200897_1_v_0_pold1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K64341947_CFM 1571 hydrochloride_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	1.0	2.72478
BRD-K23673040_(Naphthalen-1-ylamino)-acetic acid [1-(5-nitro-furan-2-yl)-meth-(E)-ylidene]-hydrazide_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Pancytopenia	CTD Gene-Disease Associations	1.0	1.04757
BRD-K42191735_buparlisib_HEPG2_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.78238
macromolecule localization	GO Biological Process Annotations 2015	1.0	null
RC-K8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.970905
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.025
ribonucleoside triphosphate phosphatase activity	GO Molecular Function Annotations 2023	1.0	null
BRD-K35133923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04854
HMGN3	ENCODE Transcription Factor Targets	1.0	null
PMC11233907-mmc9.xlsx-S8-Table_S8_Colocalization_Analysis_for_MR_TWAS_PWAS_Hits_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
IM-95	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37503
GB-73-QS80_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.315916
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the endocrine system	GWASdb SNP-Phenotype Associations	1.0	0.093017
17555561-Table2	GeneSigDB Published Gene Signatures	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5J6-01A-31R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE120612_6_v_3_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
2105_DDX18_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.635006
PMC7902901-Table_12.xlsx-EBF1-Unnamed_7_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K32021110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.32947
BRD-K25203350	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58817
VTA1	Pathway Commons Protein-Protein Interactions	1.0	null
COQ8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0471
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.22702
BRD-A19500257_geldanamycin_HT29_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
regulation of cellular ph	GO Biological Process Annotations 2015	1.0	null
YY1	ENCODE Transcription Factor Targets	1.0	null
AP3B1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7097-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BTNL3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0060643
H3K4me1_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE231799_3_v_4_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.049
BRD-K51574318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11511
GSE186810,GSE186813_2_v_0_furin_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7806814-41598_2020_80145_MOESM3_ESM.xlsx-CombinedResults_TreatbySexMainE-Supplementary_Table_S2_Genes_with_significant_FDR_0_05_sex_by_LPS_treatment_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K78126613_MENADIONE_SKM1_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Colorectal adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.36
REST	ENCODE Transcription Factor Targets	1.0	null
gtpase activity	GO Molecular Function Annotations 2015	1.0	null
Perturb_1430_KO_Adm2_SRP399375	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.25552
H3K9ac_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ADAMTS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20371
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VPS33A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE169205_3_v_5_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
regulation of cellular component organization	GO Biological Process Annotations 2015	1.0	null
vesicle membrane	GO Cellular Component Annotations 2015	1.0	null
PGAM5	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K22595044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07669
STAM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00536491
MAP1S	Pathway Commons Protein-Protein Interactions	1.0	null
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056303
reticular nucleus of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.907314
phagosome-lysosome fusion	GO Biological Process Annotations 2025	1.0	null
phagosome-lysosome fusion	GO Biological Process Annotations 2015	1.0	null
GTEX-QMR6-1326-SM-32PLB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5799
PA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QCQG-1526-SM-48U25	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31554
GSE168458_1_v_3_disulfiram_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CCNT2	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A83326220_BRAZILIN_VCAP_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K46162352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20567
CRCGN016_MCF10A.TP53.M_24H:O18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.23981
BRD-K25200031	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01247
SOX2-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.78374
EED	ChEA Transcription Factor Targets	1.0	null
CDIPT	Pathway Commons Protein-Protein Interactions	1.0	null
marrow cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.131228
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.433
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
ELK1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAP1	Pathway Commons Protein-Protein Interactions	1.0	null
19286929-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1755
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K25176380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33696
17616640-TableS1	GeneSigDB Published Gene Signatures	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN008_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4339
r5 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22179
TDOTT	DepMap CRISPR Gene Dependency	1.0	2.29745
CD3E	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00764711
ventromedial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.99011
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K74701308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08946
Lymph_Node-intermediate monocyte	Tabula Sapiens Gene-Cell Associations	1.0	0.0424368
Agranular insular area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.10624
POLR2A_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-13q34_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S4P3-1626-SM-3K2AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39518
TMEM41B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18478
paracentral lobule, anterior part, left, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.983084
PHLDA2	Pathway Commons Protein-Protein Interactions	1.0	null
NANOG-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PLEKHF2	Pathway Commons Protein-Protein Interactions	1.0	null
APPL2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE175787_11_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver-endothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	0.343857
GTEX-Q2AG-0011-R10A-SM-2HMLA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4977
daunorubicin-4983	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
IGSF10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00660677
BRD-K37764012_PF-3758309_HEPG2_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-369-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
VD-88-MW70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.581408
SMC4	Pathway Commons Protein-Protein Interactions	1.0	null
MCMBP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00556578
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.37222
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
SMARCA4-20176728-TROPHOBLAST STEM CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
20371479-TableS2	GeneSigDB Published Gene Signatures	1.0	null
GTEX-XLM4-2926-SM-4AT59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02722
EEF2K	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00507808
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A5W7-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cilostamide	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.32
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.38944
Vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
kawain-7369	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04594
GSE213588_8_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TMEM9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00516057
mRNA_TCF7L2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K74399971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61758
GSE178714_5_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE223908,GSE223909_4_v_8_serpinb3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
orbital frontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.989009
stratum oriens of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.845303
WA-15-KX40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.215022
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.41196
TAOK1	Pathway Commons Protein-Protein Interactions	1.0	null
Zfp961	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.6206
CRCGN016_MCF10A.WT.HP_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.38145
MAFK_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
BRD-K59369769_tozasertib_MCF10A_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BCKDK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28115
r6 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09396
GSE100316_0_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RPS6KA3	Pathway Commons Protein-Protein Interactions	1.0	null
RMGI	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.42508
GTEX-T5JW-1626-SM-3GADZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926169
GSE248769_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN013_HEPG2_24H:D13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.60207
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.1512
YD-49-HM53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.76795
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A42L-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7480058-95058-2020.08.29.20182899-10.xlsx-1ModuleKeyDrivers-Target_gene_Ensembl_that_KD_acts_upon_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SOX2-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
BRD-K73227539	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08001
ICOS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00520672
TAOK3	Pathway Commons Protein-Protein Interactions	1.0	null
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.982248
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00756
GTEX-N7MS-0011-R1a-SM-2HMJG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36385
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R53T-0226-SM-48FEH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868145
hela cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.412391
BRD-K74694052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33134
CHD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11071
Declive (VI)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23948
P31FUJ	CCLE Cell Line Gene CNV Profiles	1.0	1.87469
REST_PFSK-1_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1	ENCODE Transcription Factor Targets	1.0	null
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.07863
BRD-K90138084	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78943
TSG101	Pathway Commons Protein-Protein Interactions	1.0	null
HCC56	DepMap CRISPR Gene Dependency	1.0	2.65311
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EFM192A	CCLE Cell Line Gene CNV Profiles	1.0	1.66753
GTEX-XV7Q-0126-SM-4BRVK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34175
BRD-K35122752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5552
BRD-K92991072_PAC 1_NCIH2073_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JO-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE108500_1_v_0_foxp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
15833844-Table2S	GeneSigDB Published Gene Signatures	1.0	null
phagosome maturation	GO Biological Process Annotations 2025	1.0	null
VCAP	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
VDR-24763502-THP-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE199092_1_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	1.0	null
BCLAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC3510027__F2	PFOCR Pathway Figure Associations 2023	1.0	null
Perturb_15698_KO_Parva_SRP331642	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.7959
BRD-K97938633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12566
EWS502	Achilles Cell Line Gene Essentiality Profiles	1.0	1.05631
TBP_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCAMP4	Pathway Commons Protein-Protein Interactions	1.0	null
GSE76771_2_v_3_atf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.36504
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.158692
BRD-K49577636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37092
GTEX-S7PM-0011-R5A-SM-3NM8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873648
BRD-K56427898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11077
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.86518
RAB3A_KO_GDS2482_705_mouse_Cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.99809
tanespimycin-1631	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-7107-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
myeloid progenitor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.129634
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-5333-01A-01R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.833845
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_3H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.54605
GATA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08335
PMC7067536__F7	PFOCR Pathway Figure Associations 2024	1.0	null
BRD-K24220535	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57926
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BLOC1S1	Pathway Commons Protein-Protein Interactions	1.0	null
RMND1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE148066,GSE157787_5_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SNX5	Pathway Commons Protein-Protein Interactions	1.0	null
GSE148066,GSE157787_9_v_1_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
valproic acid_homo sapiens_gpl570_gse14973	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A83387524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31402
STAT4-19710469-TH1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
cytoplasmic vesicle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.160863
VAC14	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K47883435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1315
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE112860_0_v_2_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SMAD2	Pathway Commons Protein-Protein Interactions	1.0	null
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.29087
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51F-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02035
IRF8-27001747-CHIP-SEQ-BMDM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_10703_KO_LRP1_SRP154940	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.71562
19096012-TableS3	GeneSigDB Published Gene Signatures	1.0	null
EGR1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:A22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.7296
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K78385490_-666_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.67391
BNIP1	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-6143-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
U343	DepMap CRISPR Gene Dependency	1.0	3.03388
Perturb_926_OE_Scnn1b_SRP272854	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.49613
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21411
BRD-K63364685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91731
RASAL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00869192
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K23192422_L-6307_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K44458042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18112
H3K4me1_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE169205_0_v_6_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
mediodorsal nucleus of thalamus_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.35301
MYO6	Pathway Commons Protein-Protein Interactions	1.0	null
COPI-coated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.802
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149264,GSE149267_9_v_1_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Anoxia	CTD Gene-Disease Associations	1.0	1.07128
VPS18	Pathway Commons Protein-Protein Interactions	1.0	null
LAMP1	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5075-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Change_in_both_CSDE1_KD_hESCs-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
endosome	GO Cellular Component Annotations 2015	1.0	null
PMC7347220__F5	PFOCR Pathway Figure Associations 2023	1.0	null
RAP2B	Pathway Commons Protein-Protein Interactions	1.0	null
GSE120612_7_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Medial geniculate complex, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27331
primary auditory cortex (core)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.27079
dorsal lateral geniculate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3268
487_ARID1B_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.521405
RUFY1	Pathway Commons Protein-Protein Interactions	1.0	null
Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.20097
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
ion binding	GO Molecular Function Annotations 2015	1.0	null
Nucleus of the lateral lemniscus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07741
LRP8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00697046
GSE158632_2_v_4_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NOL9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00441017
suggesting	GeneRIF Biological Term Annotations	1.0	null
CORL24	CCLE Cell Line Gene Expression Profiles	-1.0	-2.12728
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
nocodazole-7145	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GET1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21531
GTEX-RU72-0011-R7A-SM-2TF5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18359
PMC5637904-PATH-243-193-s016.xlsx-human_down_in_fat_SOX11-Unnamed_7_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ASH1L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00618665
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NAPG	Pathway Commons Protein-Protein Interactions	1.0	null
Lateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12851
GSE174498,GSE174500_2_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AB-97-BI36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.344727
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25019
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
organelle organization	GO Biological Process Annotations 2015	1.0	null
amygdaloid complex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.890291
GSE89767_2_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOSL1_KO_GSE43695_681_mouse_lung, bleomycin treated	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
monocrotaline-2749	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.506265
XCT 790	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.46
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
paracentral lobule, posterior part, left, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.58273
PCI-4B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRBN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00431105
OSBPL11	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.34065
stolon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.15141
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.872916
endocrine system disease	GWASdb SNP-Disease Associations	1.0	0.165118
Perturb_14475_KO_Trim28_SRP305340	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.57837
AR-35413990-HUMAN-ARPOSCRPROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.853409
GSE186483_1_v_4_lrrk2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ACO2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00352283
ROCK1_knockdown_156_GSE34769	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.67628
NANOG-18347094-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
ARL8B	Pathway Commons Protein-Protein Interactions	1.0	null
SARS-CoV MA15_Day1_None_GSE49262	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.32851
GSE223008_7_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE241036_4_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
coronary artery disease	GWASdb SNP-Disease Associations	1.0	0.563434
PCTP	Pathway Commons Protein-Protein Interactions	1.0	null
Crus 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47206
BRCA1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8563-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRO-1926-SM-2S1O3	GTEx Tissue Sample Gene Expression Profiles	1.0	2.13455
PDGFRA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00684619
HA1E	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.514
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
bone marrow disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.268332
LMSU_STOMACH	CCLE Cell Line Proteomics	1.0	2.62233
BRD-K54606188_(+)-JQ1_HCC515_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-R2-A69V-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreas	GTEx Tissue Gene Expression Profiles 2023	1.0	1.45048
TAOK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00618142
Golgi apparatus	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.502
BRD-K16189898_CHIR-99021_HA1E_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-OIZI-0005-SM-2XCED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39735
BRD-K49878220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.001
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44667
cytoplasmic membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.333979
BRD-K27754030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21983
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventral medial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14633
Te	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.572
CLASP2	Pathway Commons Protein-Protein Interactions	1.0	null
PMC11461876-42003_2024_6975_MOESM3_ESM.xlsx-Supplementary_Data_1-Supplementary_Data_1_Differentially_Expressed_Genes_HSE_THP1_Vs_THP1_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28613
GSE242555_1_v_0_fn3k_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TNFRSF11A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00464793
OELE	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.26681
15902281-TableS1c	GeneSigDB Published Gene Signatures	1.0	null
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Vomiting	CTD Gene-Disease Associations	1.0	1.1617
GSE223008_5_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_2-Methoxyestradiol_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0138308
DB	GDSC Cell Line Gene Expression Profiles	-1.0	-1.46568
GSE184892_4_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062577
SW403	CCLE Cell Line Gene CNV Profiles	1.0	2.3818
occipito-temporal gyrus, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07243
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08923
H3K18ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lateral visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20688
BRD-K96839404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57894
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
17660535-TableS4a	GeneSigDB Published Gene Signatures	1.0	null
GSE135350_3_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.58065
r4 part of pontine raphe cell population	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42551
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73834
GTEX-OHPM-1626-SM-2HMK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05543
OB olfactory fiber layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.25992
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28795
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K64535513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60392
Lung squamous cell carcinoma_LUSC_TCGA-77-A5FZ-01A-31R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
r8 part of inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.08487
PTP4A1	Pathway Commons Protein-Protein Interactions	1.0	null
r9 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31142
Anterior cingulate area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.99922
GSE183327,GSE183328_3_v_0_ddit3_human	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE254526,GSE254528_0_v_1_phf19_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN009_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.575
BRD-K68202742_trichostatin A_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC5095001-oncotarget-07-36293-s002.xlsx-Table_S2-Table_S2_MYCN-correlated_genes_and_their_correlations_with_other_transcription_factors_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
HCC56	CCLE Cell Line Gene Expression Profiles	1.0	1.35267
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EXOC4	Pathway Commons Protein-Protein Interactions	1.0	null
SH3GL2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3	ENCODE Transcription Factor Targets	1.0	null
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.837522
DB-88-VW47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.252876
Intrinsic component of Golgi membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.162
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	2.02971
primary visual cortex (striate cortex, area V1/17)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.75463
Choroideremia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
17483295-TableS1	GeneSigDB Published Gene Signatures	1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.65775
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81914
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE115364_0_v_1_idh3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE186810,GSE186813_2_v_1_furin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5088-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r5 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15553
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Testicular Diseases	CTD Gene-Disease Associations	1.0	1.04501
GSE149943_2_v_3_cd8a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH1563	CCLE Cell Line Gene CNV Profiles	1.0	1.77633
SLC7A4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00361288
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
protein localization	GO Biological Process Annotations 2015	1.0	null
Intestinal benign neoplasm	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.946
CL-40	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.901488
2747_ESYT1_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	3.637
Mammary-macrophage	Tabula Sapiens Gene-Cell Associations	1.0	0.466766
ELK4	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-X4XY-1726-SM-46MVO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61451
Main olfactory bulb, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58604
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CLCN7	Pathway Commons Protein-Protein Interactions	1.0	null
vesicle fusion	GO Biological Process Annotations 2023	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A7B2-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HNRNPM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00558688
CRCGN013_HEPG2_24H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3141
IST1	Pathway Commons Protein-Protein Interactions	1.0	null
GATA2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SNX14	Pathway Commons Protein-Protein Interactions	1.0	null
EBF1	ENCODE Transcription Factor Targets	1.0	null
STX7	Pathway Commons Protein-Protein Interactions	1.0	null
GATA3_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCL20	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00589972
GSE223008_7_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K18ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SOX2-21211035-LN229-GBM	ChEA Transcription Factor Targets 2022	1.0	null
GSE152441,GSE152442_6_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WYJK-0826-SM-3NM8Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05736
GSE213410_2_v_3_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RNF2-18974828-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE207863_0_v_1_hdac5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC35C1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00527417
SH2D1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00570932
ventrolateral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.23493
GTEX-QCQG-1426-SM-48U22	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920588
MTF2	ChEA Transcription Factor Targets	1.0	null
TRIM28	ENCODE Transcription Factor Targets	1.0	null
Secondary lysosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.786
ChIP_TRIM28_19339689	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
intercalated cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.747515
GSE147613_1_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1468
GSE224547_1_v_0_cftr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TA-34-CK62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.969912
CEBPB_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pinosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.543176
FOXA1_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LZTS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22481
BRD-K49865102_PD-0325901_HCC515_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Mycophenolic acid	DeepCoverMOA Drug Mechanisms of Action	-1.0	-1.47
hsa-miR-4755-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
BUD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00705
CD226	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00521183
internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE221577_1_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE68155_1_v_0_gpr3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K99411983_-666_SKB_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TRIM28	Pathway Commons Protein-Protein Interactions	1.0	null
orbital frontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27623
SELENBP1	Pathway Commons Protein-Protein Interactions	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06554
Anterior cingulate area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81155
BRD-K83297764	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77845
SRY-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CDC42	Pathway Commons Protein-Protein Interactions	1.0	null
GATA3	ENCODE Transcription Factor Targets	1.0	null
TLN1	Pathway Commons Protein-Protein Interactions	1.0	null
EXOC8	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
Lung adenocarcinoma_LUAD_TCGA-69-7979-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.121
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-655	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GOLIM4	Pathway Commons Protein-Protein Interactions	1.0	null
SEPTIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22873
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K74710236_VU0410183-2_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE115395_2_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
M10 melanoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.834
GTEX-R55E-2526-SM-2TC6H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.861611
GSE125157_1_v_0_piceatannol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE217776,GSE217829_4_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	1.0	null
ME-77-JX81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.322307
GSE148066,GSE157787_5_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARFGEF2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00446149
GSE211286_7_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K68257399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71361
HCC70_BREAST	CCLE Cell Line Proteomics	1.0	4.39385
Primary bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.403
r10 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02503
LEPR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00816683
MRPS14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06598
KAT2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00461832
Bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.362
EPRS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00639596
GTEX-U8XE-0626-SM-3DB8U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29219
H3K4me1_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Quinidine (15% dihydroquinidine)_Hs 766T	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00367155
GSE148066,GSE157787_3_v_1_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9996951-40659_2023_417_MOESM3_ESM.xlsx-Osteo_vs_MSC_Array2_hypo_er_txt-Downstream_NAME_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
ChIP_NR0B1_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
layer 3 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56889
Anemia, Hemolytic	CTD Gene-Disease Associations	1.0	1.02373
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.877527
ZEB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ4-0226-SM-2S1NW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834349
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95833
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-M7-A71Z-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
HS 766T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50885
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-gene_id_x_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5700-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DF-00-BU08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.481468
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3Y4-01A-51R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in postamygdaloid region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.870117
SNX1	Pathway Commons Protein-Protein Interactions	1.0	null
BORC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.951
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09066
nucleus of the central acoustic tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71563
RAB8A	Pathway Commons Protein-Protein Interactions	1.0	null
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.70757
GSE211286_4_v_6_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J5-01A-21R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RINT1	Pathway Commons Protein-Protein Interactions	1.0	null
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A7VF-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H4K20me1_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211286_1_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE197555_1_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-PX3G-0126-SM-2I3EN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12079
GSE127790_4_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
Organ system benign neoplasm	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.946
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SDF4	Pathway Commons Protein-Protein Interactions	1.0	null
Verapamil_COLO 205	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0219263
intermediate stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11164
Lung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.06919
GSE223008_4_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PIK3R1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-NFK9-0626-SM-2HMIV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28878
PMC9218776-ADVS-9-2104640-s002.xlsx-SIM_-_Nurr1-Nurr1_modulation_mediates_neuroprotective_effects_of_statins_SIM2	Rummagene Transcription Factor Associations 2026	1.0	null
SJSA1	CCLE Cell Line Gene CNV Profiles	1.0	2.53082
GMP reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.969
ARHGAP8	Pathway Commons Protein-Protein Interactions	1.0	null
ZBTB7C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7073
A388	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K67578145_GDC-0879_MCF7_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11615
BRD-K30121969	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09256
SW1783_CENTRAL_NERVOUS_SYSTEM	CCLE Cell Line Proteomics	1.0	2.96826
CTCF_choroid plexus epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A08003242_RHODOMYRTOXIN B_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
pancreatic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.072784
TAF5L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00650426
SW1463	GDSC Cell Line Gene Expression Profiles	1.0	1.78096
GTEX-PWOO-2426-SM-2S1OV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54323
GTEX-UTHO-0011-R11A-SM-3GIJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.81906
CTCF-33576154-HUMAN-LIVER-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.89417
vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CTCF_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20842
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.660922
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09461
PCYOX1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K16136897	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12723
BRD-K96076719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.04642
GSE184087_4_v_5_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
CEBPB_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.42116
PMC6347712-pnas.1812449116.sd05.xlsx-iPSC_IRF7_48h_RNAExpress-Gene_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K23703519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66553
GTEX-RM2N-1626-SM-2TF5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12798
GSE203158_1_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PE/CA-PJ15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17517
Lysosomal glycocalyx	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.965
GSE178714_5_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE133691_1_v_3_lgr5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9950457-mmc3.xlsx-GRHL2_overexpression_DOWN-gene_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
vorinostat_homo sapiens_gpl571_gse18544	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GDI2	Pathway Commons Protein-Protein Interactions	1.0	null
dorsal lateral geniculate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02802
H4K20me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DYNC1I2	Pathway Commons Protein-Protein Interactions	1.0	null
TRAIP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00551729
GSE211286_4_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GATA2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8XE-1026-SM-4E3HM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12822
ZNF454	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	159.343
YAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12554
FOXD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14683
BRD-K44494409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01611
GSE92589_0_v_1_sirolimus_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
IC-05-AW29_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.242706
BRD-K08806664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51505
GSE211286_4_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE140997_4_v_6_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UJMC-0426-SM-4IHJF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841949
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17517
medial parabrachial nucleus,right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.960568
MCF7_SGI-1776 free base_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0216073
RRAS	Pathway Commons Protein-Protein Interactions	1.0	null
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Decreased_in_both_CSDE1_KD_hESC-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CEBPB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.26688
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.220321
PTPN1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE166944_0_v_2_eif4b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OCUM1	CCLE Cell Line Gene Expression Profiles	1.0	1.67761
PACSIN2	Pathway Commons Protein-Protein Interactions	1.0	null
superficial stratum of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14541
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
19837975-TableS1	GeneSigDB Published Gene Signatures	1.0	null
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.52384
Fatty Liver	CTD Gene-Disease Associations	1.0	1.437
SPI1-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE117042_0_v_3_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SW 1990	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38169
BRD-K71414336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31075
organelle fusion	GO Biological Process Annotations 2015	1.0	null
primary motor cortex (area M1, area 4)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.906051
GTEX-RWS6-1026-SM-47JXD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884483
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.381
GSE128730_3_v_1_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-R55E-0011-R11A-SM-2TC6I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7658
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89471
hsa-miR-2467-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
K562_Sodium Phenylbutyrate_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.01822
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02353
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.970114
GSE180277_0_v_1_bach2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.55992
SUZ12-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
IZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14671
BRD-K01976263_Emetine Dihydrochloride Hydrate (74)_TYKNU_6.0_h_0.63_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE167546_1_v_2_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K20138377	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50406
CRCGN017_MCF10A.TP53.M_24H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.31815
GSE171826_1_v_0_rosiglitazone_human	RummaGEO Drug Perturbation Signatures	1.0	null
connexin	GeneRIF Biological Term Annotations	1.0	null
GSE118794_5_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE220520_5_v_4_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K20906316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35033
GTEX-PW2O-0126-SM-48TC8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03576
BRD-K77594363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19905
TAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051916
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95093
BRD-K65127260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3742
BRD-K05605336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21899
uterine cervix	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.298165
BRD-K24170552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65578
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAB33A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00588566
Piriform area, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44347
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EG-11A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BLOC-3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.46
KLF5-25053715-YYC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-HIF1_HIF2_miRNA_targets_hyp-HIF2_-related_miRNA_targets_expression_during_hypoxia_based_on_micorarray_FC_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U3ZM-0126-SM-3DB8M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05185
BRD-K30533903	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34884
GSE251992_1_v_0_saracatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNF8	Pathway Commons Protein-Protein Interactions	1.0	null
EXOC7	Pathway Commons Protein-Protein Interactions	1.0	null
DYNC1LI2	Pathway Commons Protein-Protein Interactions	1.0	null
ChIP_H3K27me3_17603471_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
nucleus accumbens, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.894291
Fetal Brain Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.899925
mRNA_MYCN_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ROS50	DepMap CRISPR Gene Dependency	1.0	3.75352
REST_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ABC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24771
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1355	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54906
TEAD4_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.90766
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NB10	DepMap CRISPR Gene Dependency	1.0	4.87053
GSE183413_1_v_2_ash1l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
18614019-TableS4c	GeneSigDB Published Gene Signatures	1.0	null
posterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.828716
single-organism membrane fusion	GO Biological Process Annotations 2015	1.0	null
GTEX-X4XX-0011-R11A-SM-46MWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.80082
BRD-K47854067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15823
GTEX-XQ3S-1126-SM-4BOPK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2508
GTEX-SUCS-0626-SM-32PM5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90521
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.209305
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPK-1626-SM-2YUN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2862
PMC11244912-media-3.xlsx-Sheet2-ESR1_mutation_E2_Co-Down_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
primary motor cortex (area M1, area 4)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.58921
5637	DepMap CRISPR Gene Dependency	1.0	3.25413
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78263
BRD-A19500257_geldanamycin_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NANOG-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K53972329_ruxolitinib_HS578T_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
OAZ1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0041203
GSE222574_0_v_2_lmna_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
phagocytic cup	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.609086
THRB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00740849
NCI 460	BioGPS Cell Line Gene Expression Profiles	1.0	1.58852
PMC11982601-IMM-175-84-s005.xlsx-Fig5D_LPS-Innate_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
OSBPL8	Pathway Commons Protein-Protein Interactions	1.0	null
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.30815
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11627398-pone.0315219.s005.xlsx-MTF1-symbol_MTF1	Rummagene Transcription Factor Associations 2026	1.0	null
FAIM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0075127
GTEX-Q2AH-1826-SM-2S1Q2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.979586
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50876
posterior (caudal) superior temporal cortex (area 22c)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.33744
Creb3l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.6644
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.143641
GSE181003_3_v_2_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE147943_7_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cortical endoplasmic reticulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.567
H3K27ac_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Change_in_both_CSDE1_KD_hESCs-gene_short_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
8517_STK24_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.702893
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K99764436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14215
BRD-K79404599_enzastaurin_HA1E_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE96641_5_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular transport	GO Biological Process Annotations 2015	1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UQCRC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00569363
NR0B1-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
endocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.573828
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7416-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27124
fisetin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00365
MCF7_Filgotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0152403
Nephritis	CTD Gene-Disease Associations	1.0	1.1437
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
chr13_110592717_T_C_b38	GTEx eQTL 2025	1.0	1.44789
BRD-K91216645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30733
GSE249404_0_v_1_oxytocin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VAMP3	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-S7SE-0011-R6A-SM-2XCD9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836429
CSNK1G1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00595337
WDR36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8381
BRD-K50008138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71147
PMC8423434-mmc7.xlsx-KLF4_HENSM-Genes_n_2172_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE227891_5_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21834
GTEX-U3ZN-1726-SM-4DXUQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.824495
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE148066,GSE157787_2_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K20043699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02279
Perturb_15827_OE_Nrf2_SRP291724	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.24688
PA-TU-8988S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.883029
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K57795803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51026
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RTLS-0526-SM-2TF64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.959355
UACC257	BioGPS Cell Line Gene Expression Profiles	1.0	1.11026
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
intracellular protein transport	GO Biological Process Annotations 2015	1.0	null
CREB1	ENCODE Transcription Factor Targets	1.0	null
MAX_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE168602,GSE168604_2_v_1_selumetinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ID4_KO_GDS4178_620_mouse_Splenic B cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
primary visual cortex (striate cortex, area V1/17)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.883442
BRD-K13299646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00668
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	1.0	2.23125
GSE195568_6_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K67689282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74995
vascular disease	GWASdb SNP-Disease Associations	1.0	0.068288
GSE172146_2_v_0_mettl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.878069
BRD-K74710236_-666_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POU2F1-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.283
BRD-K73839552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19045
SLC47A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00485444
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55675
Lung squamous cell carcinoma_LUSC_TCGA-22-4594-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AU565	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.573854
AB-00-IL62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.495313
GSE186483_6_v_4_lrrk2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SNU-719	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.3045
lomustine-7094	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HT29	BioGPS Cell Line Gene Expression Profiles	1.0	0.946014
ZNF384_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K50841342_PAC 1_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Thymus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.234
Tetrachlorodibenzodioxin	CTD Gene-Chemical Interactions	1.0	null
BRD-K58113140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16461
GSE195582_3_v_1_pim1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
chemdependency	GAD High Level Gene-Disease Associations	1.0	0.293278
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-Row_names_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K19766710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38502
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SMAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7326
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K22420708	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16601
NGF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00639111
LIVF001-029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87899
GSE114883_0_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00821
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67L-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.19037
CRCGN015_HEPG2_48H:H06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.28492
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61G-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
thyroid gland disease	GWASdb SNP-Disease Associations	1.0	0.244353
Mammary-vascular associated smooth muscle cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0746194
ARHGAP18	Pathway Commons Protein-Protein Interactions	1.0	null
FERMT1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE192663_3_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H4K20me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K56285711	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04156
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063424
Lung squamous cell carcinoma_LUSC_TCGA-22-5483-11A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FE-10-KQ78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.240758
PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67N-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prelimbic area, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24499
H3K4me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE140997_10_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ALKBH7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31607
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SH3GLB2	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN011_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6467
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.897426
hESC_Derived_CD56+_Ectoderm_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.831592
GSE192689_0_v_3_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GOLGA7	Pathway Commons Protein-Protein Interactions	1.0	null
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
HL60	Achilles Cell Line Gene Essentiality Profiles	1.0	1.56439
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.16744
CTHRC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00627777
GSE74528_0_v_1_trex2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Endocytic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Perturb_17408_KO_Rag2_SRP092590	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.54745
GTEX-T2IS-0826-SM-4DM6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846647
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Lung squamous cell carcinoma_LUSC_TCGA-22-1005-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ALDH6A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.007001
BRD-A84941884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56249
NFIC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7347220__F5	PFOCR Pathway Figure Associations 2024	1.0	null
NCIH1792	Achilles Cell Line Gene Essentiality Profiles	1.0	1.07739
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26408
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-6690-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7235-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE163275_1_v_0_irf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.159268
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RHEB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07206
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0162
GSE158197_6_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LGALS9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00611289
TLR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00617673
BRD-K14706855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71398
BRD-K08730634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01705
Perturb_1603_KO_Tlr4_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.69424
GSE230329_0_v_3_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NEDD1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K13849122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00111
BRD-K32918816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.25136
BRD-K45842176_-666_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LMO2-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_3122_KO_Slc6a14_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.65368
CRCGN015_MCF10A_48H:E02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0118
TBX20-22328084-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
A4/FUK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01997
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HDAC6_KO_GSE27896_383_mouse_Foxp3+ T-regulatory cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE214823,GSE214824_3_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
XPOT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00477336
mRNA_SMAD7_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GSE210580_5_v_2_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MM1S	Achilles Cell Line Gene Essentiality Profiles	1.0	1.0874
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.870218
KRT5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00536492
striatum_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3467
GSE142210_3_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_3hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of CoPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34978
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU478	DepMap CRISPR Gene Dependency	1.0	3.0206
GSE195568_1_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.97228
Topotecan	CTD Gene-Chemical Interactions	1.0	null
GTEX-WHSE-1126-SM-3NMBU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848321
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QK-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE195568_3_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-NPJ8-2626-SM-2D7W2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93376
NANOG-18347094-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE158632_2_v_1_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
lidocaine-1999	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE137653_2_v_3_siglecf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K99498722_S1176_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K50212643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2467
GALC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00495925
Brain Lower Grade Glioma_LGG_TCGA-DB-A4XD-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K49630774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82835
abdomen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.232039
Brain Lower Grade Glioma_LGG_TCGA-S9-A89Z-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Posterolateral visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38789
urinary bladder cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.248554
bed nucleus of stria terminalis, lateral amygdaloid division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0357
NCI-H2172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.846593
NCI-H520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.925751
BRD-K36713925	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05109
BRD-K76431854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14542
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Decreased_in_both_CSDE1_KD_hESC-hgnc_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Cortical amygdalar area, anterior part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04114
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21614
BRD-A61304759_tanespimycin_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Post-translational protein modification	Reactome Pathways 2024	1.0	null
TCF7L2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZW10	Pathway Commons Protein-Protein Interactions	1.0	null
organelle membrane	GO Cellular Component Annotations 2015	1.0	null
MON2	Pathway Commons Protein-Protein Interactions	1.0	null
ZEB1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K43053725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87581
NCI-H1876	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Tubercle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.663
GSE213588_10_v_7_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Sertoli cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
TMEM266	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00683669
ACAP2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE178340_5_v_4_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10082046-41467_2023_37049_MOESM6_ESM.xlsx-Sheet1-Supplementary_Data_3_Genes_downregulated_in_ASPS-KY_cells_by_ASPSCR1-TFE3_knockdown_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28279
Lung squamous cell carcinoma_LUSC_TCGA-98-A53D-01A-32R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_3685_KD_MEX3A_SRP321087	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E18-E20_624_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE242199_2_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCAPG	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-VJWN-0426-SM-3GIJI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.9112
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
DKMG	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.08079
GTEX-WZTO-0011-R10B-SM-4E3KB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70133
GTEX-S4Q7-0426-SM-3K2BJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15278
GSE134375_6_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OB outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10065
GSE242083,GSE242098_3_v_4_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE114685_1_v_0_grin2b_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE227698_2_v_4_g0s2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.0634
CIB1	Pathway Commons Protein-Protein Interactions	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ras protein signal transduction	GO Biological Process Annotations 2015	1.0	null
LGALS16	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00439359
HCC1599	CCLE Cell Line Gene CNV Profiles	-1.0	-2.35139
ITPK1	Pathway Commons Protein-Protein Interactions	1.0	null
10219_ZNF226_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.593786
FCGR3B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00502143
GSE226285_3_v_0_nr0b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	1.0	3.14306
KLF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	97.7106
BMI1	ChEA Transcription Factor Targets	1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.168598
MG-262-7079	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Nervous System Malformations	CTD Gene-Disease Associations	1.0	1.16533
PITPNA	Pathway Commons Protein-Protein Interactions	1.0	null
RAB35	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE60837_0_v_3_bcl9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
THAP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16296
REST_Panc1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE130383_2_v_3_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DCAF16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75728
SPTLC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30836
KLF11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	121.36
GTEX-S95S-1426-SM-2XCDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.970409
HDC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00669502
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46694
ELOVL7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00470323
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.68977
BRD-K99749624_S1003_SKB_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RABL2A	Pathway Commons Protein-Protein Interactions	1.0	null
OB glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.28345
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
UNCX	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00701554
CRCGN012_HEPG2_24H:N19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01391
BRD-K51575138_TPCA-1_EFO27_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K07770425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39625
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A76A-01A-51R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE144443_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CD14+_Monocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.05094
PMC3255547-supp_007401_DMM007401TableS6.xls-EWS-FLI1_signatures-Table_S6_Overlap_of_differentially_expressed_genes_in_Tg_HSP_EWS-FLI1_embryos_and_human_EWS-FLI1_signature_from_Smith_et_al_2006_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158815_5_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NAAA	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-NFK9-1126-SM-3LK78	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.981417
BRD-K00509183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85589
KP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02113
15833844-Table2a	GeneSigDB Published Gene Signatures	1.0	null
GTEX-PX3G-1626-SM-2S1PT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935367
GSE203485_1_v_0_zdhhc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HSC4_UPPER_AERODIGESTIVE_TRACT	CCLE Cell Line Proteomics	1.0	3.38074
ANXA6	Pathway Commons Protein-Protein Interactions	1.0	null
TBC1D1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-S7SE-0011-R5A-SM-2XCDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39177
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46694
MCF7_Tucidinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0185124
ABC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4635
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.29087
GSE210580_4_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.053
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
pargyline-2102	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SCA1_Knock-in_GDS1756_232_mouse_Cerebellum tissue - 12 weeks of age	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
macropinocytic cup	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.24027
Perturb_8364_KD_STAT3_SRP411741	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
fastigial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.29738
GSE206516,GSE206518_6_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K05804651	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11732
r8 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56459
H3K9ac_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCIH441_LUNG	CCLE Cell Line Proteomics	1.0	2.26477
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T5JC-2326-SM-32PMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853733
TMD8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23012
monocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.162188
BRD-K13803936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41739
624 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.950454
SP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.87365
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RHOT2	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
MDAMB436_BREAST	CCLE Cell Line Proteomics	1.0	2.32126
TD-69-UA90_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.241978
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Thorax	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.234
PMC3435504-msb201237-s2.xls-Supp_Table_4c-CEBP_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
membrane	GO Cellular Component Annotations 2015	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05125
CEBPB	ChEA Transcription Factor Targets	1.0	null
GSE127790_5_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Small_Intestine-neutrophil	Tabula Sapiens Gene-Cell Associations	1.0	0.0102464
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K73524144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18402
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23801
lomofungin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.026
SPI1	ENCODE Transcription Factor Targets	1.0	null
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE140997_10_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PPARG-20887899-3T3-L1 PREADIPOCYTE CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K54278059	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79218
SW982	DepMap CRISPR Gene Dependency	1.0	3.36452
BC-10-SB73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203578
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5443-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE95685_4_v_5_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hnf4a_21852396_wao9_lof_human_gpl570_gds3926	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.06837
EP300_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hematopoietic stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.120975
BOK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20501
TT	GDSC Cell Line Gene Expression Profiles	-1.0	-1.62373
RAP1A	Pathway Commons Protein-Protein Interactions	1.0	null
TNP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19844
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5454-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.60459
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.66299
BRD-K02708799_GSK-1059615_HEPG2_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6B1-01A-12R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CREB1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
precommissural nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.884599
GSE135350_2_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRCA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:F22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4117
KLF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.192
phagosome maturation	GO Biological Process Annotations 2023	1.0	null
GSE195559_2_v_5_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148066,GSE157787_2_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GF-37-MB64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.296322
subbrachial nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.91471
STX18	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K36772364_8-{[2-oxo-2-(1-pyrrolidinyl)ethyl]thio}quinoline_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K92991072_PAC 1_MDST8_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
VASP	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ovarian Neoplasms	CTD Gene-Disease Associations	1.0	1.39142
BRD-A28105619_curcubitacin I_OV7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
20963824-Table2	GeneSigDB Published Gene Signatures	1.0	null
CHEK1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K11672894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1841
increased circulating sodium level	MGI Mouse Phenotype Associations 2023	1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
GSE131673_0_v_1_arid1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XOTO-0011-R11B-SM-4B64O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21883
intracellular protein transport	GO Biological Process Annotations 2023	1.0	null
GTEX-P4PP-0526-SM-2HMKE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860473
GSE149903_0_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAP2K3	Pathway Commons Protein-Protein Interactions	1.0	null
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K14211116	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56402
Sarcoma_SARC_TCGA-K1-A3PO-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-8186-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.919086
r9 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70199
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PDE6H	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00584234
Perturb_9550_KO_Becn1_SRP255651	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.10779
TCF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4862
STEAP3	Pathway Commons Protein-Protein Interactions	1.0	null
NCIH196	Achilles Cell Line Gene Essentiality Profiles	1.0	1.65889
RUNX3	ENCODE Transcription Factor Targets	1.0	null
GSE48812_11_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
EXOC5	Pathway Commons Protein-Protein Interactions	1.0	null
PMC3435504-msb201237-s2.xls-Supp_Table_4b-MYBL2_MYBL2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7480058-95058-2020.08.29.20182899-10.xlsx-1ModuleKeyDrivers-Target_gene_symbol_that_KD_acts_upon_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC8851354-Table_5.xlsx-Ruxolitinib_reg_FD-bound-Supplementary_Table_5_Genes_regulated_by_ruxolitinib_that_are_FUS-DDIT3_targets_in_MLS_402-91_cells_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K10484463_1483-0018_ASC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-VJYA-0726-SM-4KL1T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1287
POLA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10895
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F6_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A59391763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17958
GTEX-RUSQ-1926-SM-2TF6K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92302
GTEX-TML8-1826-SM-32QOR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54826
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K00265832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71844
ADK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00615145
7477_RPL7A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.43994
7515_RPS26_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.28296
Tongue squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.07
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.968363
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K67868012_PI-103_HEPG2_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FOXO1-23066095-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAL51	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.08594
5-lipoxygenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.595
PMC6987220-41467_2020_14312_MOESM5_ESM.xlsx-P53_Spheres-0_names_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146072_0_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Fra-1_KO_GDS5078_403_mouse_Lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
USF2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZN-0126-SM-4DXUM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11213
GSE114883_0_v_4_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.56252
GSE118794_0_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RNOR-2326-SM-2TF4I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19018
Cytoplasmic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-SP5_SP5	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K49865102_PD-0325901_HCC515_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-A09533288_VERAPAMIL HYDROCHLORIDE_RKO_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
WDR33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06271
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.7508
XE-69-AT35_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.239966
GSE100316_0_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SUZ12-18974828-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SYK_knockdown_280_GDS3609	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.63573
Turner Syndrome_CNS - Brain (MMHCC)_GSE1606	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.85715
REPS1	Pathway Commons Protein-Protein Interactions	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.0617
Lung Diseases	CTD Gene-Disease Associations	1.0	1.32846
PMC7818749-12931_2021_1617_MOESM1_ESM.xlsx-TBX4-SYMBOL_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
19235837-TableS2b	GeneSigDB Published Gene Signatures	1.0	null
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3196
FE-82-WB22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.96236
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K92241597_CHR 2797_PL21_6.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE150032,GSE181873_3_v_1_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BL-41 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.68
GSE220693_1_v_0_cgas_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PWO3-1026-SM-2I5F2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14762
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.23212
HUP-T4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.963694
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21335
CISD2	Pathway Commons Protein-Protein Interactions	1.0	null
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053235
NCIH508	CCLE Cell Line Gene CNV Profiles	1.0	1.75199
CAPAN-1	GDSC Cell Line Gene Expression Profiles	1.0	1.65652
GSE130715_1_v_0_budesonide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Neoplasms	CTD Gene-Disease Associations	1.0	1.61667
BRD-K31325635	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15064
GTEX-O5YV-1026-SM-3LK72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01427
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
heterocyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
PML_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4QR-0726-SM-2I5GO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.944952
TBL1-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
EGR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.3158
BRD-K74710236_-666_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NFIC	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-Q734-0226-SM-48U1A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05541
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AP-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.929594
GSE168587,GSE168752_3_v_1_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K48207398	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14833
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.850709
GSE237984_1_v_0_magi1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92387
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4422	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
outer SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19305
CTNNB1-20460455-HCT116-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.085
GSE129153_0_v_1_forskolin_human	RummaGEO Drug Perturbation Signatures	1.0	null
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K08307026_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
4908_MCOLN1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.29662
GSE190322,GSE190324_3_v_4_rbm4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
gastroesophageal reflux disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.393746
macrophage cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.565631
MXI1	ENCODE Transcription Factor Targets	1.0	null
small intestine	HPA Tissue Protein Expression Profiles	1.0	1.8234
phagocytic vesicle	GO Cellular Component Annotations 2015	1.0	null
GSE96641_5_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6995218-12864_2020_6525_MOESM3_ESM.xlsx-D2FED48h_vs_D2FAST48h_968_AR-DE-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
r6 part of spinal trigeminal nucleus, pars oralis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49138
Gastrointestinal system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.246
BRD-K05804044_AZ-628_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K36855468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1186
BRD-K58017833	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01738
GSE232631_0_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cortex of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14425
Lung squamous cell carcinoma_LUSC_TCGA-51-4079-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nerve Degeneration	CTD Gene-Disease Associations	1.0	1.08407
BRD-K19580273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28659
POLR2A_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K11506071	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55166
MCF7_BMS-754807_1µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0145669
ELF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BLOC1S2	Pathway Commons Protein-Protein Interactions	1.0	null
PMC4387713-supp_gad.255984.114_Table_S4.xlsx-S4A-Down_Nanog_KD-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.081
PITPNM1	Pathway Commons Protein-Protein Interactions	1.0	null
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K99545815_HY-10459_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TCEAL3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00546979
acebutolol-1911	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
vesicle organization	GO Biological Process Annotations 2015	1.0	null
hsa-miR-502-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
19218430-TableS3	GeneSigDB Published Gene Signatures	1.0	null
GTEX-WYJK-0005-SM-3NMA1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00289
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15867
COPB2	Pathway Commons Protein-Protein Interactions	1.0	null
Basolateral amygdalar nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39039
BRD-K67563379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6799
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.863809
Carcinoma, Squamous Cell	CTD Gene-Disease Associations	1.0	1.15122
anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.057937
DSCAM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00647429
ph reduction	GO Biological Process Annotations 2015	1.0	null
TRIM28-17542650-NTERA2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K25866212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1101
BRD-K01436366_-666_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
emetine-2145	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-SSA3-0326-SM-32QPS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01616
GTEX-U8XE-0526-SM-3DB8R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09656
GTEX-QXCU-0626-SM-2TC69	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824588
TXLNA	Pathway Commons Protein-Protein Interactions	1.0	null
PMC8787225-Data_Sheet_1.xlsx-STable_2_DEG-Supplementary_Table_2_1150_up-_and_down-regulated_differential_expressed_genes_upon_GATA2_activation_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE153871_1_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K38634661_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K60728944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59465
stratum radiatum of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39681
PAWR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00567803
PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_ENSEMBL_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_13763_KO_Uqcrq_SRP284268	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.67742
NHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.3197
PNKP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00549733
GTEX-XUJ4-1726-SM-4BONW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835843
Lung squamous cell carcinoma_LUSC_TCGA-39-5040-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Alveolar lamellar body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.802
HD-MY-Z	GDSC Cell Line Gene Expression Profiles	-1.0	-1.82522
cell part	GO Cellular Component Annotations 2015	1.0	null
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15657
BRD-K01850737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04231
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPARG	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K57464717	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47891
GSE152441,GSE152442_1_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
DBTRG05MG	DepMap CRISPR Gene Dependency	1.0	2.47919
KF-18-RY71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.494642
CRCGN015_MCF10A_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.6003
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947557
FOXM1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder-pericyte cell	Tabula Sapiens Gene-Cell Associations	1.0	0.510662
Lung squamous cell carcinoma_LUSC_TCGA-43-7658-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3150b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
hsa-miR-382	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
ChIP_CNOT3_19339689	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
striatum_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.37689
regulation of biological quality	GO Biological Process Annotations 2015	1.0	null
PMC7681055-ACEL-19-e13226-s014.xlsx-Sheet1-Ryk-independent_FOXO3_targets_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9170821-JCMM-26-3183-s001.xlsx-Mic_DAPI_ERG_VaD_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K87872414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40087
SOX2-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Benign neoplasm	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.946
NEK6	Pathway Commons Protein-Protein Interactions	1.0	null
GUSB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00457135
BRD-K55598155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69794
GSE174701_5_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH2291	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36323
GSE247764_0_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary auditory cortex (core)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03842
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.827166
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K37486644	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05129
JUN-21703547-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ENPP3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0064282
RKN	CCLE Cell Line Gene CNV Profiles	-1.0	-2.20312
BRD-K34741587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25529
GSE210655_3_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ATP6V1B2	Pathway Commons Protein-Protein Interactions	1.0	null
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.42893
CHP1	Pathway Commons Protein-Protein Interactions	1.0	null
Inflammation	CTD Gene-Disease Associations	1.0	1.90869
GALC	Pathway Commons Protein-Protein Interactions	1.0	null
PCBP1_02_115	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60516
EDNRB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00746246
PRDM1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hypothyroidism	DisGeNET Gene-Disease Associations	1.0	null
MDAMB175VII	CCLE Cell Line Gene Expression Profiles	1.0	1.55985
GSE110178_5_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CDK5	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DHCR7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00401738
EPB41L5	Pathway Commons Protein-Protein Interactions	1.0	null
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.19641
SCFD2	Pathway Commons Protein-Protein Interactions	1.0	null
intracellular part	GO Cellular Component Annotations 2015	1.0	null
C5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00388706
H3K9ac_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE217541,GSE217543_0_v_2_tet1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
GSE126463_5_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IO-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09345
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05749
HIP1R	Pathway Commons Protein-Protein Interactions	1.0	null
mammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08367
CRCGN013_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.67873
TREM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00532653
GSE96777,GSE96778_3_v_2_zbtb4_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K17771527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61788
Acute Lung Injury_Lung Tissue_GSE1871	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.65597
Hematopoietic stem cell_Bone marrow_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.52172
ARHGAP35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18398
Kidney renal clear cell carcinoma_KIRC_TCGA-6D-AA2E-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prelimbic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40868
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A770-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K09434518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59544
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.901488
GSE184479_3_v_2_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nucleus of the lateral lemniscus, horizontal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.91812
r4 part of reticulotegmental nucleus, shell portion	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01839
ventrolateral periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25774
GOLPH3	Pathway Commons Protein-Protein Interactions	1.0	null
Golgi apparatus	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
ERBB2IP	Pathway Commons Protein-Protein Interactions	1.0	null
nephron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.099509
CRCGN011_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1174
CYP2S1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00758177
GSE161295_0_v_1_cdk8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-VUSG-1526-SM-4KKZH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835125
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ATF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.31584
JAK1	Pathway Commons Protein-Protein Interactions	1.0	null
PATU8902	DepMap CRISPR Gene Dependency	1.0	7.15787
GTEX-NPJ8-0011-R11A-SM-2YUMS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52998
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
MAX_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K54606188_(+)-JQ1_HCC515_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
769P_KIDNEY	CCLE Cell Line Proteomics	1.0	4.39385
olfactory bulb, principal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09007
BRD-K18070214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81185
GSE142210_9_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
amygdaloid complex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.959744
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
EZH2-27304074-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K85708426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06639
MAFF	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
10455_ZNF567_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.640505
GTEX-POMQ-0126-SM-48TD6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00511
GSE125219,GSE125221_3_v_8_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_16725_KO_Ncor2_ERP131241	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC38	CCLE Cell Line Gene CNV Profiles	-1.0	-2.02924
ASPC1_PANCREAS	CCLE Cell Line Proteomics	1.0	3.08003
BRD-K94294671_A-1065_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
USP28	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00540572
FLI1-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
cis-Golgi network	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.039
HCC2157	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57107
IRF1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE110178_1_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.916175
ZNF280B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00530411
Perturb_1669_KO_Rigi/Mda5_SRP119759	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.06177
SW1417_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	2.35415
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
plexiform layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27331
anterior (rostral) cingulate (medial prefrontal) cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.962818
GTEX-S7PM-0526-SM-3NM92	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.579
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01219
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AS-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AG-2826-SM-2HMJQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.47373
monovalent inorganic cation homeostasis	GO Biological Process Annotations 2015	1.0	null
BLOC1S4	Pathway Commons Protein-Protein Interactions	1.0	null
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K82883803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17067
Perturb_5895_KD_CCDC137_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.50846
macropinosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.681591
GABPA_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05271
NKG7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00803118
H3K27ac_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC9170563-12885_2022_9665_MOESM3_ESM.docx-0-Candidata_target_genes_of_CEBPB_6_CEBPB	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7346435-12864_2020_6860_MOESM6_ESM.xlsx-H1_ZF_Oocyte_Specific-Gene_SymbolH_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
IRF1	ENCODE Transcription Factor Targets	1.0	null
KMS-21BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.31436
Temporal association areas, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40237
PMC7902901-Table_12.xlsx-ATF3-Unnamed_7_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.701949
hsa-miR-1260	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Declive (VI), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28432
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0011-R8A-SM-2HMK5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2139
HB-06-WU12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.251561
GSE189772,GSE189773_3_v_2_fbxo11_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
digoxin-5324	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE226285_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNU840	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.50341
OTX2_KO_GDS4440_424_mouse_brain (fourth ventricular choroid plexus)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE233183,GSE233187_2_v_9_larp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Simvastatin	DeepCoverMOA Drug Mechanisms of Action	-1.0	-1.31
GSE130383_1_v_0_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.32132
parthenolide-1736	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-1299	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
BRD-K85441584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08314
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18585
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.872916
DCTN2	Pathway Commons Protein-Protein Interactions	1.0	null
Skin - Not Sun Exposed (Suprapubic)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.08082
NCIH508	CCLE Cell Line Gene Expression Profiles	1.0	1.6598
STARD7	Pathway Commons Protein-Protein Interactions	1.0	null
EED-16625203-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
3054_FECH_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.744774
DDX59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35442
layer 4 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40798
H3K9me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.036235
tdif1knockeddown	GeneRIF Biological Term Annotations	1.0	null
primary motor cortex (area M1, area 4)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13665
thymus	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
IGF1_OE_GDS3484_538_human_MCF-7	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE66014_0_v_1_perhexiline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Colon - Transverse	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.00374
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.4553
lateropallial prepiriform area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37406
GSE157383_0_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTPase activity	GO Molecular Function Annotations 2025	1.0	null
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.2259
GTEX-RWSA-1426-SM-47JXA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04999
Late endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.825
BRD-A28746609_-666_ASC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
macrophage	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.433374
GSE100316_5_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PSMB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23447
BRD-K69932463_AZD-8055_MDAMB231_3_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K55612106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0728
USF2_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AE-13-CX28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.226967
TROAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13163
SIRT3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00333672
GTEX-T5JW-0126-SM-4DM6K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0765
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4818-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN012_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.55315
UBF1/2-26484160-CHIP-SEQ-FIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H4K20me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DHX37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56519
BRD-K39107553	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54909
GATA2	ENCODE Transcription Factor Targets	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.983
BFSP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00738017
DD-36-YH76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.752404
NCI-H1299 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.774
IQGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53631
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830695
GSE210580_5_v_6_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
orbital frontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10098
SNAPIN	Pathway Commons Protein-Protein Interactions	1.0	null
Contractile vacuole complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.844
amygdalostriatal transition area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.847667
Kidney renal clear cell carcinoma_KIRC_TCGA-3Z-A93Z-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Trachea-macrophage	Tabula Sapiens Gene-Cell Associations	1.0	0.911579
PMC6995218-12864_2020_6525_MOESM3_ESM.xlsx-D2FAST48h_vs_D4REFED48h_750_AR--Gene_Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053898
BRD-K18637162	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97934
GTEX-RWS6-2126-SM-2XCAV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0825
Perturb_9546_KO_Cdk7b_SRP257915	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.72565
Bed nuclei of the stria terminalis, posterior division, transverse nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05558
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QVUS-0226-SM-3GIJY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10471
PD-05-HV36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.276658
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E4-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAB39	Pathway Commons Protein-Protein Interactions	1.0	null
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2873-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN009_HEPG2_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.23105
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CPLX1	Pathway Commons Protein-Protein Interactions	1.0	null
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.85583
GSE159893_2_v_1_genistein_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A85860691_chaetocin_HA1E_24.0_h_0.08_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.911645
MECP2_KD_GDS4759_334_mouse_E16 primary cortical neuron cultures	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
E2F6	ENCODE Transcription Factor Targets	1.0	null
adrenal gland	HPA Tissue Gene Expression Profiles	1.0	0.997182
SKBR3	CCLE Cell Line Gene Expression Profiles	1.0	1.6809
GSE151782_3_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE196117_6_v_8_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K82135108_elesclomol_MDST8_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE196505,GSE196507_1_v_2_kdm2b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SART1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00500442
BRD-K47748211	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01213
Griscelli syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.623
AdrenalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
BRD-K81418486_vorinostat_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K44432556_VU0418946-2_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE192689_0_v_1_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.89069
PMC10702478-jci-133-161348-s262.xlsx-High_targets8listes_TPM_DE-List_of_high_confidence_targets_of_PPAR_genes_regulated_after_18h_in_Mo_by_PA_PPARA	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN009_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.79714
dorsolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.878512
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4075-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0316
Ectorhinal area/Layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79286
BRD-K30310008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09917
BRD-A78085235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66961
CFTR_Deficiency_GDS1843_192_mouse_Lungs - Animals examined at 6 weeks of age	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.202
SW 527	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02511
ME-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04246
BRD-K06148621	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4052
GSE158197_0_v_11_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843082
POR_KO_GDS1678_762_mouse_Jejunum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-A52475911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09107
H3K79me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC11076560-42003_2024_6230_MOESM5_ESM.pdf-50-KLF7_KLF7	Rummagene Transcription Factor Associations 2026	1.0	null
GSE205976,GSE205978_1_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TGFBRAP1	Pathway Commons Protein-Protein Interactions	1.0	null
LN235	Achilles Cell Line Gene Essentiality Profiles	1.0	1.32167
TCF12_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HPAF-II	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.7534
OCUG1	DepMap CRISPR Gene Dependency	1.0	2.59688
INSIG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17416
posterior (caudal) superior temporal cortex (area 22c)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04184
MAPK1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE211989_3_v_2_nlrc3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K49424866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03078
STAT1	Pathway Commons Protein-Protein Interactions	1.0	null
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.29124
NFI-21473784-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
RAB21	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K38998073	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98354
HES1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2205
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3451-01A-02R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ion homeostasis	GO Biological Process Annotations 2015	1.0	null
BACH1	ENCODE Transcription Factor Targets	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.26845
7332_RNASEK_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.590859
MTF2-20144788-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4EP-0726-SM-3P5YJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22889
lateral orbital frontal cortex (area 12/47)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.44364
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cingulate gyrus, retrosplenial part, left, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1984
IGFBP5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0058482
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RUNX1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
GSE193258,GSE193259_9_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
STAT5B	Pathway Commons Protein-Protein Interactions	1.0	null
Liver Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.2393
BRD-K64640769	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.30728
gallbladder	HPA Tissue Protein Expression Profiles	1.0	0.78613
BRD-K88510285_B675700.cdx_A549_24.0_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ChIP_SOX2_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-WVLH-2926-SM-3MJG5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30491
H3K4me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Anterior cingulate area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.04097
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Gustatory areas, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29958
heart muscle	HPA Tissue Protein Expression Profiles	1.0	1.8234
DDX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20686
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K19295594_-666_A549_6.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K29614616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46728
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K27178321	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03801
PMC8185471-mmc4.xlsx-D2-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_2_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
GSE233049_1_v_3_atf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_JK_LPS-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.22567
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947847
GSE201309_1_v_0_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213588_8_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.915
GSE197257_0_v_1_gpd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-27b	TargetScan Predicted Conserved microRNA Targets	1.0	0.32519
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-EGR1_DC_ChIP-seq_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04184
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.13851
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.86672
EOMES-21245162-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K42873980	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53228
Ectorhinal area/Layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5413
Main olfactory bulb, inner plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31527
PRKCZ_KO_GDS4310_293_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5Q5-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PA1	DepMap CRISPR Gene Dependency	1.0	4.69794
BRD-A89554862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.11879
GSE123638,GSE123639_0_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.8236
GSE186483_2_v_0_lrrk2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE145476_2_v_0_hopx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Q fever	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63339
SHARPIN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00402257
GTEX-WHSE-0926-SM-3NMBS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1759
GTEX-T2IS-2926-SM-32QPO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78144
phagosome acidification	GO Biological Process Annotations 2025	1.0	null
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213588_8_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SET2	CCLE Cell Line Gene CNV Profiles	1.0	1.90779
MAX_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.65864
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K01973494	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15484
PDS5B	Pathway Commons Protein-Protein Interactions	1.0	null
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EXOC2	Pathway Commons Protein-Protein Interactions	1.0	null
EGR3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.1642
496100586_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.46458
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.473
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Leukopenia	CTD Gene-Disease Associations	1.0	1.17993
golgi apparatus	LOCATE Predicted Protein Localization Annotations	1.0	null
PPP1R1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00642658
FBP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00508905
KPL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.916831
CUX1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K10989535	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16931
GSE184399_0_v_2_cnot1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157036,GSE166411_3_v_1_halofuginone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:N07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.036
BRD-K60794504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34796
lateral medullary reticular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.838595
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.92693
VCAP	CCLE Cell Line Gene Expression Profiles	1.0	2.18905
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4151-01A-01R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dot1l_DELETION_GDS4295_426_mouse_AF9 - Mixed Lineage Leukemia (MLL) cells - 3 days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SNX8	Pathway Commons Protein-Protein Interactions	1.0	null
Autolysosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.562
GSE182680,GSE182683_0_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-Q2AG-0426-SM-2S1PU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19713
DAUDI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.829563
BRD-K53488735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11803
ADRM1	Pathway Commons Protein-Protein Interactions	1.0	null
TBC1D16	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00598618
Brain Lower Grade Glioma_LGG_TCGA-FG-A6J3-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YD-49-HM53_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.483712
BRD-K44177822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90029
ING4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00582903
BRD-K18594025	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28051
2291_DNAJC17_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.785654
GSE223008_6_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXO1	ChEA Transcription Factor Targets	1.0	null
layer 1 of LPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73702
BRD-K09373762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04098
artery disease	GWASdb SNP-Disease Associations	1.0	0.095564
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
FOXM1	ENCODE Transcription Factor Targets	1.0	null
Golgi stack	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.127
bounding membrane of organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.066992
KA-29-AB08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.313804
RKN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.922473
hsa-miR-3159	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.15863
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.89069
H3K27ac_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K70511574_sunitinib_HEPG2_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K52978625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32488
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04195
BRD-K42486632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41674
Artery - Aorta	GTEx Tissue Gene Expression Profiles 2023	1.0	1.65751
GSE168473_0_v_1_isoniazid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RN64-1026-SM-48FDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7254
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51486
SNU869	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GSE221633_0_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	1.0	null
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.89069
BRD-K27543887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26231
CHD7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00471469
SIN3A	ENCODE Transcription Factor Targets	1.0	null
FE-64-KC49_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.626751
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.424963
REST_PFSK-1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K95323755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0157
Cell type benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.175
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
LAMP2	Pathway Commons Protein-Protein Interactions	1.0	null
253J	DepMap CRISPR Gene Dependency	1.0	2.49949
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-N7MS-0011-R11A-SM-2HMJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.98194
SMAD4-21741376-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BC-82-PP66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.232157
HDAC2	ENCODE Transcription Factor Targets	1.0	null
diltiazem-1948	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-SJXC-0526-SM-2XCFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13852
TBC1D17	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K71726959_N9-isoproplyolomoucine_A549_24.0_h_122.55_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Liver-macrophage	Tabula Sapiens Gene-Cell Associations	1.0	1.85388
BRD-K88658905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23477
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.173003
REST_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KA-75-LP02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.261531
GTEX-RNOR-2226-SM-2TF5O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45356
NDUFAF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63249
Hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.176
CDK1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K58268854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62232
FAM129B	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54343
ZNF384_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
atherosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.265819
BRD-K85123403_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-4709-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
PMC5932012-41467_2018_4180_MOESM18_ESM.xlsx-Table_19-GSEA_Gene_lists-Zuber_Myb_KD_UP_HUMAN_AR	Rummagene Transcription Factor Associations 2026	1.0	null
VPS26A	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-CoV MA15_Day1-PFU-10^4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.01209
GTEX-T6MN-2626-SM-32PMQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39331
GSE205550,GSE205552_2_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
0179445-0000-3630	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K12440228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0676
I-II	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.63205
GTEX-WFG7-2226-SM-3GIKP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.993972
GSE148692,GSE148695_2_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Purkinje cell layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07775
BRD-K40264914	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75006
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
Endocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.26
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PDS5A	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN008_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5955
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10297
BRD-K42918627_GSK-2126458_HT29_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
lateral amygdaloid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49524
POLR2A_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KIF5B	Pathway Commons Protein-Protein Interactions	1.0	null
GSE199606_1_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_Fulvestrant_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00795326
CRAT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00520714
TLR9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00681949
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRDM1	ENCODE Transcription Factor Targets	1.0	null
BRD-K76910883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44583
BA-84-WN26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.338456
mRNA_GATA3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE77178_2_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211177,GSE211178_9_v_3_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OXRL-1626-SM-2YUMU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41223
SKMEL2_SKIN	CCLE Cell Line Proteomics	1.0	3.20608
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A47816767_-666_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46G-01A-31R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051684
BD-69-XG81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.39081
CC-08-JZ09_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.463702
GSE176555,GSE176556_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZFX_KO_GDS2718_150_mouse_embryonic stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
MS4A6E	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00707875
signal transduction	GO Biological Process Annotations 2015	1.0	null
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K4me3_CD19 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K39813155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33006
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
apical plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.264946
regulation of endocytosis	GO Biological Process Annotations 2015	1.0	null
PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-HIF1_HIF2_miRNA_targets_hyp-Unnamed_12_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_Lapatinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0128424
CD56+_NKCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.27136
RB1	Pathway Commons Protein-Protein Interactions	1.0	null
thorax	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
H3K4me1_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE206516,GSE206518_1_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VDR-24787735-THP-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.946
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PTPN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00364017
SKP1	Pathway Commons Protein-Protein Interactions	1.0	null
RAB13	Pathway Commons Protein-Protein Interactions	1.0	null
fenspiride-2106	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CA-75-HA22_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.379537
NANOG	ChEA Transcription Factor Targets	1.0	null
BRD-A52193669_2816_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN015_MCF10A_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3159
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.26977
Rectum adenocarcinoma_READ_TCGA-G5-6233-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUM1315MO2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.988497
bipolar disorder	GWASdb SNP-Disease Associations	1.0	0.562455
GSE124410_3_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WYJK-1726-SM-3NM9U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1853
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE147240_3_v_4_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
KC-48-OO62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.499384
monocytic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.190047
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.475
alzheimer's disease	GWASdb SNP-Disease Associations	1.0	0.55372
GSE264621_1_v_3_secretin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K61717269_-666_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CLN5	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K50841342_PAC 1_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TTC19	Pathway Commons Protein-Protein Interactions	1.0	null
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ADGRE1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00540708
GSE148066,GSE157787_2_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GNAQ	Pathway Commons Protein-Protein Interactions	1.0	null
withaferin A-4554	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K17239874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16616
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUS-01A-12R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XBED-2626-SM-4E3J5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.95157
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K72648699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26637
CLPB	Pathway Commons Protein-Protein Interactions	1.0	null
Fetal Growth Retardation	CTD Gene-Disease Associations	1.0	1.01324
TLR4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00436626
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_upreg-mouse_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
organic substance transport	GO Biological Process Annotations 2015	1.0	null
DUSP3	Pathway Commons Protein-Protein Interactions	1.0	null
PMC5263239-mmc2.xls-MV4_11_-_MLL-AF4-Non-spreading_targets_gene_names_1985_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
glia	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063476
Paramedian lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14657
TYK-NU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.17671
LIVF001-023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.90803
GSE231799_3_v_1_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0827
HCC1482	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.897693
H3K4me3_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Uterus-macrophage	Tabula Sapiens Gene-Cell Associations	1.0	1.00522
GTEX-XV7Q-2326-SM-4BRVZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900847
Gastrointestinal system benign neoplasm	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.946
estradiol_homo sapiens_gpl96_gse4668	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LRRC8A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00964413
H3K4me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
basolateral amygdaloid nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79993
BIN1	Pathway Commons Protein-Protein Interactions	1.0	null
regulation of vesicle-mediated transport	GO Biological Process Annotations 2015	1.0	null
SKMG1	DepMap CRISPR Gene Dependency	1.0	2.30063
SW403	CCLE Cell Line Gene Expression Profiles	1.0	2.04939
BRD-A27640568_5846833_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
amygdaloid complex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.9482
Endopiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18141
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.011
AGK	Pathway Commons Protein-Protein Interactions	1.0	null
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12286
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.52326
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08092
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.07
BICR18	CCLE Cell Line Gene CNV Profiles	1.0	1.59809
GTEX-NL3H-0011-R11A-SM-2I3E6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.19305
RAB1A	Pathway Commons Protein-Protein Interactions	1.0	null
YKT6	Pathway Commons Protein-Protein Interactions	1.0	null
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.8583
GSE247775_1_v_0_tmprss2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-2L-AAQL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K00317371_-666_COV644_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE178255_2_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7399-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skbr3	HPA Cell Line Gene Expression Profiles	1.0	0.94868
A3/KAW	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.43598
mantle zone of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0906
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GSE110178_1_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
lateral terminal nucleus of the accessory optic tract, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35041
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.983
PRKAR2A	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47895
BRD-K72128077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.25164
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC5792454-mmc2.xlsx-Table_S5-Table_S5_Genes_up_or_down_regulated_in_murine_Hoxa9_IRX3_leukemias_versus_Hoxa9_MTV_leukemias_Gene_Ontology_annotations_IRX3	Rummagene Transcription Factor Associations 2026	1.0	null
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.25547
JURKAT, CLONE E6-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18226
BRD-K08109215_I-BET_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PLK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00543646
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A897-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SJ-01A-12R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDC42SE2	Pathway Commons Protein-Protein Interactions	1.0	null
UBE2Q2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00635959
GTEX-QXCU-0326-SM-2TC63	GTEx Tissue Sample Gene Expression Profiles	1.0	1.034
GTEX-R55D-0826-SM-48FEA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831568
GSE223008_5_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11076560-42003_2024_6230_MOESM5_ESM.pdf-50-ENSG00000118263_KLF7	Rummagene Transcription Factor Associations 2026	1.0	null
IMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41516
PMC12703482-AMS-21-5-213605-s2.xlsx-Supplementary_Table_SXIV-SMR_results_of_expression_levels_of_VDR_target_genes_in_peripheral_blood_and_risk_of_melanoma_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
ES-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.859932
GSE226285_3_v_1_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
Erlotinib_HCT15	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0148025
HOXD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29996
GSE155031_5_v_0_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25T-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DEFB106B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00484911
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Rucaparib_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00928453
GTEX-WL46-0011-R1A-SM-3LK6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30867
EXOC6	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-MW-A4EC-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTPase activity	GO Molecular Function Annotations 2023	1.0	null
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.157
EGR1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
6801_PRPF4_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.697505
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43005
KYSE-520	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.123082
GSE162575,GSE162609_3_v_2_tfe3_human	RummaGEO Gene Perturbation Signatures	1.0	null
OCI-LY-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37503
SJSA1	DepMap CRISPR Gene Dependency	1.0	5.40821
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
fat_8b	HPA Tissue Sample Gene Expression Profiles	1.0	0.927456
7424_RPAP3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.669804
GSE152734,GSE152735_1_v_0_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE124932_2_v_1_sarm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91107
Brain Lower Grade Glioma_LGG_TCGA-KT-A7W1-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE225901_2_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-X4XX-3026-SM-3NMB2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.943597
primary motor cortex (area M1, area 4)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01649
JAR	DepMap CRISPR Gene Dependency	1.0	2.41227
OGFOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47341
STXBP3	Pathway Commons Protein-Protein Interactions	1.0	null
Myocardial Infarction	CTD Gene-Disease Associations	1.0	1.04352
Trichocyst	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.674
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hematopoietic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.080556
FD-59-TC81_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.398764
BRD-K07551625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05292
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202587_1_v_2_xrn1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
17069664-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
Tongue cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.139
GSE186810,GSE186813_2_v_0_furin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11479675-NIHMS2019542-supplement-2.xlsx-D_HIF1A_genes-Unnamed_1_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U3ZN-2226-SM-3DB88	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05696
KLHDC8B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00536789
RSV-A2_24Hour-KO_RSV_None_GSE18170	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	0.987441
GSE248045,GSE248046_0_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K34192219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41782
RSL1D1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00588198
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE158458_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OOBK-0226-SM-2YUMF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995136
GSE205163,GSE205164_2_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
ID-69-QF93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.225896
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
Postsynaptic Golgi apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.612
rosiglitazone_homo sapiens_gpl570_gds2453	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MT-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.19062
endocytic vesicle membrane	GO Cellular Component Annotations 2015	1.0	null
SPI1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
dorsolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11531
rab9	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.886
SOX17-20123909-XEN-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
VPS36	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83T-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q734-0126-SM-48U1E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31504
NAGLU	Pathway Commons Protein-Protein Interactions	1.0	null
LXR-22158963-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC11309649-medi-103-e37185-s002.xlsx-Sheet1-FOS_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
GSE100316_3_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ampyrone-2086	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE133661_0_v_1_c19orf12_human	RummaGEO Gene Perturbation Signatures	1.0	null
mononuclear cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.138057
SIRT7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00465016
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044419
GSE96777,GSE96778_1_v_0_zbtb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10828500-41467_2024_44701_MOESM4_ESM.xlsx-ST12-Unnamed_7_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22131
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.946
BRD-K54606188_(+)-JQ1_HCC515_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RAB25	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE253089_0_v_1_ephb2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-REY6-0926-SM-48FDA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00041
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.34029
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08439
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
F5	DepMap CRISPR Gene Dependency	1.0	6.22723
EPAS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00650179
late endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.375434
SPI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
establishment of localization in cell	GO Biological Process Annotations 2015	1.0	null
BRD-K15834839_-666_SKB_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE125007,GSE125008_4_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KDM1A_KD_GDS5055_457_mouse_adipose tissue	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ELK1	ChEA Transcription Factor Targets	1.0	null
GTEX-XQ8I-1126-SM-4BOO2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37292
SMAD3-21741376-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SNX6	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.922473
raw-264.7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.650966
ARAF	Pathway Commons Protein-Protein Interactions	1.0	null
GSE111035,GSE111040_3_v_12_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00503346
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
r5 part of the oral Sp5 subnucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.69977
NR0B1	ChEA Transcription Factor Targets	1.0	null
STX4	Pathway Commons Protein-Protein Interactions	1.0	null
CEP55	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00617375
KMT2D	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00888823
LGR5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00576223
BRD-K43051162	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29377
GSE183890_7_v_10_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4731966-13195_2015_167_MOESM9_ESM.xlsx-SEKI_LPS_Up-Unnamed_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
LAPTM5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00632009
GSE68155_3_v_2_gpr3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GATA3-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-33-4587-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Posterolateral visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00802
layer 5 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30829
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.957054
PDCD4	Pathway Commons Protein-Protein Interactions	1.0	null
eGFP-GATA2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Entorhinal area, medial part, dorsal zone, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06264
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5011-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4P3-0426-SM-4AD56	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.997777
GSE95688_7_v_2_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
IZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.851451
Squamous cell carcinoma of mouth_Oropharynx Epithelium_GSE3524	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.57825
BRD-A94046266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9684
Brain Lower Grade Glioma_LGG_TCGA-HT-A74O-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.890093
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8324-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VCAP	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
BRD-K14216332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02164
FD-81-SU40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207237
GSE140997_2_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
USP36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07223
Duodenum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MRPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26918
GSE230744,GSE237803_0_v_3_hira_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DNAJC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29352
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.42496
PMC12703482-AMS-21-5-213605-s2.xlsx-Supplementary_Table_SXVII-SMR_results_of_expression_levels_of_VDR_target_genes_in_peripheral_blood_and_risk_of_sarcoma_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
ERP27	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00463628
GSE200839,GSE233826_5_v_4_tnrc18_human	RummaGEO Gene Perturbation Signatures	1.0	null
H4K20me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K16136457	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04007
ATP6V1E1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN014_HEPG2_24H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06072
spleen_3b	HPA Tissue Sample Gene Expression Profiles	1.0	1.42439
TBC1D15	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K32862555_NCGC00183412-01_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K20284960	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35646
layer 1 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05997
BRD-K51520673	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56406
PL21	CCLE Cell Line Gene CNV Profiles	1.0	2.15233
GTEX-WK11-2526-SM-3NM9Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40516
GSE184892_6_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
QF-00-NO42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.273301
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1	ChEA Transcription Factor Targets	1.0	null
H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
increased circulating sodium level	IMPC Knockout Mouse Phenotypes	1.0	null
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K12665145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09158
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.94908
GTEX-WVLH-0011-R6A-SM-3MJFZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02236
abnormality of the cerebral white matter	GWASdb SNP-Phenotype Associations	1.0	0.479232
Anterior olfactory nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55237
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4323
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.867729
SUZ12-16625203-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K82837433_-666_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
USP7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00514098
VPS51	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KO52	CCLE Cell Line Gene CNV Profiles	1.0	1.41017
SELENOI	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00554088
GSE169571_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.86803
SKMEL30	DepMap CRISPR Gene Dependency	1.0	5.21058
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00821
mRNA_POU5F1_20526341	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GTEX-X4XX-0011-R10B-SM-46MWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907563
BRD-A19500257_geldanamycin_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_2day-MOI-10^3_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.74098
BRD-A78360835_cercosporin_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE121319_1_v_0_gprc5a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.145
GTEX-PW2O-0526-SM-2I3DX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867671
GSE123638,GSE123639_2_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ELK4_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Spleen	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.944989
MCF7_Gandotinib_1µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0136274
19658189-TableS4	GeneSigDB Published Gene Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.02895
pontine nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01535
GSE127790_10_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K78599730_manumycin A_A549_24.0_h_9.08_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K82433264	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36859
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K12281552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97015
GSE169152_5_v_4_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Main olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19576
GSE148510_3_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCT-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13088
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
membrane region	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.074894
ANAPC7	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K50046044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49428
2132_DDX56_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.526587
MAZ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.0728
layer V of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21667
EGR1	JASPAR Predicted Transcription Factor Targets	1.0	null
RHOG	Pathway Commons Protein-Protein Interactions	1.0	null
GSE140936,GSE140938_0_v_1_slfn11_human	RummaGEO Gene Perturbation Signatures	1.0	null
TA-34-CK62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200055
GSE223008_9_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S7SE-0011-R4A-SM-2XCDB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.33027
r5 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07978
guanyl nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
IHO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00588142
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-U412-0226-SM-3NMC8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07322
Perturb_8504_KO_Hr_SRP200420	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.29893
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.63049
RAD21	ENCODE Transcription Factor Targets	1.0	null
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11167
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75135
layer 2 of LPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61765
ATP6V0C	Pathway Commons Protein-Protein Interactions	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15412
CRCGN015_HEPG2_48H:B21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.04143
ZBTB7A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K52500055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46754
Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J1-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARFGEF2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K43324262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6709
Acute Myeloid Leukemia_LAML_TCGA-AB-2897-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paralemniscal isthmic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31028
PPARG-20887899-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CF-87-AS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.75067
TAFAZZIN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00559448
BRD-K90673570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13263
Kidney renal papillary cell carcinoma_KIRP_TCGA-KV-A6GD-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-W5WG-1926-SM-4KKZK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27379
BRD-K65182930_NVP-AUY922_HT29_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE127790_9_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I0-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K17840858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35025
BRD-K76907295_VU0418947-2_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
COL4A4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00763094
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922449
Leukemia	DisGeNET Gene-Disease Associations	1.0	null
HDAC1	ENCODE Transcription Factor Targets	1.0	null
BRD-K14117311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50878
PMC12337709-mmc3.xlsx-Wild-type_vs_RAG1_KO_Myeloid-Unnamed_1_RAG1	Rummagene Transcription Factor Associations 2026	1.0	null
mRNA_EOMES_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SGK3	Pathway Commons Protein-Protein Interactions	1.0	null
CEACAM19	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00534243
posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13718
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
TNFAIP8	Pathway Commons Protein-Protein Interactions	1.0	null
GSE242367_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE205163,GSE205164_2_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A19500257_geldanamycin_HT29_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4827-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIM28-19339689-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ERLIN2	Pathway Commons Protein-Protein Interactions	1.0	null
Lung Neoplasms	CTD Gene-Disease Associations	1.0	1.49558
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Unnamed_1_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
MAD2L1BP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00391646
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.078532
TC-O 9311	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.35
KLF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.386
KLF17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	83.0509
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMAD4	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1395	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.03807
localization	GO Biological Process Annotations 2015	1.0	null
TICRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26828
GSE208096_1_v_0_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PW2O-1726-SM-2S1OO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02082
UACC812	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4645
AMY1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00581939
TCFAP2C-20176728-TROPHOBLAST STEM CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
496100495_FWM_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.4598
AKR1A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00612394
TAF1	ENCODE Transcription Factor Targets	1.0	null
GSE196117_6_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nucleus of the lateral olfactory tract, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44422
STAT1-19122651-HELAS3-HUMAN-CERVICALCANCER	ChEA Transcription Factor Targets 2022	1.0	null
LS1034	CCLE Cell Line Gene Expression Profiles	1.0	1.40411
BRD-K06403738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3348
GSE160246_0_v_5_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0612
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.15079
GTEX-P4QT-0126-SM-2I3FL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19475
GTEX-T2IS-0011-R6A-SM-32QP2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08424
BRD-K53198140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10824
GSE96991,GSE97117_5_v_0_il11_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U4B1-1926-SM-3DB9E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950738
ventral lateral nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12915
GTEX-UJHI-0126-SM-4IHLP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4534
HINFP	JASPAR Predicted Transcription Factor Targets	1.0	null
RAD21_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG7-0526-SM-3GIKI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910063
BRD-K32445732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7841
BRD-K35960502_NICLOSAMIDE_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.959942
RSU1	Pathway Commons Protein-Protein Interactions	1.0	null
KA-29-AB08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.411448
PSAP	Pathway Commons Protein-Protein Interactions	1.0	null
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.91157
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7434-11A-01R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K99564685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12582
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FZD10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00478487
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RELA_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE181966_5_v_3_has2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135350_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
COLO684	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62615
nucleoside phosphate binding	GO Molecular Function Annotations 2015	1.0	null
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE114284_1_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K64132098	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42666
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_CCRFCEM_ChIP-seq_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K47504528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87061
UK 383367	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.58
Etoposide	CTD Gene-Chemical Interactions	1.0	null
GTEX-S7SE-2526-SM-2XCDL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.80865
GSE126463_0_v_3_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K79me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Whole Blood	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.04152
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
19567819-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-QVJO-1325-SM-2S1QX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48431
GTEX-WYVS-0006-SM-3NMA7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35779
GTEX-OOBJ-1626-SM-2I3F7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6118
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.882634
MCF7_JNJ-7706621_1µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0116745
Fusiform vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.525
endocytic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE85565_1_v_0_tcf21_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TAF1_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lymph node	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.003
estradiol_homo sapiens_gpl1225_gse1486	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
A-CA-04-2009(H1N1)_Day3_22532695_GSE36328	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.88061
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WVLH-0011-R2A-SM-3MJFJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.87351
TBCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15795
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.79254
BRD-K59535072	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20807
16488994-SuppTable1b	GeneSigDB Published Gene Signatures	1.0	null
ABI1	Pathway Commons Protein-Protein Interactions	1.0	null
HTT	Pathway Commons Protein-Protein Interactions	1.0	null
DA-69-UN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.592635
AC-36-SY22_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204263
PMC2820592-NIHMS144142-supplement-8.xls-LMS_SAM_3-GENES_HIGHLY_EXPRESSED_IN_GROUP_III_LMS_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	1.0	2.29069
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6875
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.908581
Tizanidine	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.48
GSE217156_1_v_3_trpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
chr13_110521350_G_C_b38	GTEx eQTL 2025	1.0	3.84595
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JD-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K43548664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32914
Skin angiosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.118
ChIP_SUZ12_16625203	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
STAT5A	ENCODE Transcription Factor Targets	1.0	null
MHCC97-H cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.819
molecular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11139
NADK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00612633
BRD-K89264608	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12918
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A55484088_BNTX maleate_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K11457257	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57862
HCC38_BREAST	CCLE Cell Line Proteomics	1.0	2.91463
SCAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23628
GSE138818_1_v_0_nanog_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RPS6KA4	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-T8EM-1326-SM-3DB7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874168
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NMRK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00650792
GSE146156_1_v_3_tagap_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K81473043_-666_HT29_24.0_h_0.35_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE182680,GSE182683_5_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
transport	GO Biological Process Annotations 2015	1.0	null
GTEX-S4UY-0426-SM-3K2AF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82473
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.71612
vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.316708
GSE175787_5_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3456-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Esmolol	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.41
PMC9218734-Supplementary_Data3.xlsx-KRIEG-KRIEG_HYPOXIA_NOT_VIA_KDM3A_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
LILRB5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00848916
GOPC	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K87080934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.48319
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
sulfadimethoxine-7400	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
16207381-Table1Sa	GeneSigDB Published Gene Signatures	1.0	null
GTEX-XV7Q-0005-SM-4BRWI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97932
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.848435
7110_RAPGEF6_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.712149
AP2A2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K66214486	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70964
GSE236504,GSE236505_0_v_1_atmin_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-1915	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
CREB3L4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2402
PMC11285331-cd-23-0539_table_s1_suppst1.xlsx-Lost_AR_Peaks-Unnamed_19_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE182179_5_v_4_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
CEBPB_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043396
GTEX-OIZH-0926-SM-48TBR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23229
GD-46-BU97_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200526
Adrenocortical carcinoma_ACC_TCGA-OR-A5KT-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9236773-7900785.f1.docx-0-PPARG_PPARG	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FNBP1L	Pathway Commons Protein-Protein Interactions	1.0	null
coronary artery disease	GWASdb SNP-Phenotype Associations	1.0	0.480014
CDC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.266
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
ZB-16-BR73_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.29351
H3K4me1_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Cytoproct	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.927
Brain - Hippocampus	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.924404
adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057416
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
MEF2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00467099
bsc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.805
isoconazole-1372	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
TEAD4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-0826-SM-3NM8Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832497
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.35441
GSE146982_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
dorsal endopiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42654
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
lateral tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29377
MNT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6325
CTCF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TADA2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00703699
ACAP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00487152
GTEX-R55D-0926-SM-3GAEU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13969
midbrain reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.57052
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney - Medulla	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.19113
NCI-H460	GDSC Cell Line Gene Expression Profiles	1.0	1.97558
DYNLL1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21997
Rab-protein geranylgeranyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.891
Macrophage_Skin_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
496100422_TCx_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.17716
endocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.404026
purine nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-QV31-1426-SM-2S1QD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900773
BRD-K70161581_-666_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ChIP_K27me3_17603471_mouseMEF	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K55728478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37467
golgi apparatus	GO Cellular Component Annotations 2015	1.0	null
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE114992,GSE114993_7_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE186810,GSE186813_2_v_1_furin_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A86109770_-666_SKB_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051536
GTEX-XUJ4-1426-SM-4BONT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04703
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Oral apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.522
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.859499
BRD-K74710236_-666_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.63105
ERK5-IN-2_HT-29	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0195196
REPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27922
GSE228261_0_v_1_elesclomol_human	RummaGEO Drug Perturbation Signatures	1.0	null
L3MBTL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00536481
SPATA5L1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00664907
BRD-K81651477_Parthenolide_SKMEL1_6.0_h_20.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.95091
layer 1 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.07888
BRD-K82877426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25951
superficial stratum of r4Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.77236
SNX2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K67484361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.44723
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.755753
layer 1 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18234
CGGBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54123
GAPVD1	Pathway Commons Protein-Protein Interactions	1.0	null
SLC17A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01299
glial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063812
NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.7267
LYN	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.946988
NHBE cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.678
GSE148692,GSE148695_2_v_6_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11906354-41588_2025_2087_MOESM4_ESM.xlsx-ST12-Unnamed_3_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K00337317_NU-7441_BT20_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02175
GTEX-WL46-2926-SM-3LK82	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54955
TJP2	Pathway Commons Protein-Protein Interactions	1.0	null
Tuberculosis	DisGeNET Gene-Disease Associations	1.0	null
GTEX-S7SE-0011-R2A-SM-2XCDC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.57802
brain disease	GWASdb SNP-Disease Associations	1.0	0.562455
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.90429
MCM2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K80995081	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2001
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.352969
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041183
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Spleen-macrophage	Tabula Sapiens Gene-Cell Associations	1.0	2.43331
PFKP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12534
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_G007-LK_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0155469
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RD-90-OY66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.425721
BRD-K47577519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16025
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN009_HEPG2_24H:C16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12381
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adult_Liver	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.07422
GSE107505_1_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182185_0_v_1_pstk_human	RummaGEO Gene Perturbation Signatures	-1.0	null
interstitial nucleus of the posterior limb of the anterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24144
GSE175787_4_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31943
placenta_6a	HPA Tissue Sample Gene Expression Profiles	1.0	2.05408
AB-09-EA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.594534
PANC0327	DepMap CRISPR Gene Dependency	1.0	4.19443
FGD4	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN014_HEPG2_24H:A03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.60841
GSE144443_5_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE197555_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_fibroblast of villous mesenchyme_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FD-59-TC81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.399177
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.860961
KIAA1033	Pathway Commons Protein-Protein Interactions	1.0	null
RSPO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0059896
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hydrolase activity, acting on acid anhydrides	GO Molecular Function Annotations 2015	1.0	null
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K24076516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37706
Perturb_6982_KO_Nlrp3_SRP173143	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.0562
BRD-K38788176	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24393
GTEX-R53T-1826-SM-3GIJX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849641
SCAMP1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K12336887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06481
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-13q34_1_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-IZ-A6M8-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_7066_KO_Lrpprc_SRP110979	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.73329
ND-39-PO34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.292866
igr37	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.557
CDX2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00719277
MPIG6B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00578817
BRD-K41538715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36532
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50459
cerebellar cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.928656
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.3487
Lung squamous cell carcinoma_LUSC_TCGA-22-4593-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K31342827_GF-109203X_PL21_6.0_h_12.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN009_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.76063
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.13738
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.574151
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.947725
BRD-K02190643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01736
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GYS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81237
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SUZ12-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE120612_7_v_3_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-REY6-1226-SM-48FDR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834784
MRPS25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60394
H3K79me2_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_3119_KO_Scarf2_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.3862
Perturb_6987_KD_Trpc6_SRP406046	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.82468
Cell tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.671
GSE169155_1_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202434,GSE202438_10_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.838673
BRD-K72615639_-666_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SUZ12	ENCODE Transcription Factor Targets	1.0	null
superior occipital gyrus, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.854206
H4K20me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.278877
ChIP_SUZ12_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX2-21211035-LN229_GBM-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL4W-0011-R11A-SM-2I3DW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24322
GSE173873_1_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
2233_DIS3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.750329
PMC9746818-jciinsight-7-152886-s077.pdf-17-ENSG00000221869_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
EoL-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.6
GTEX-S341-1726-SM-3K2AK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.829693
RHCE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00611016
COPB1	Pathway Commons Protein-Protein Interactions	1.0	null
DOPEY2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VC-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.26526
GSE147662_3_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ROCK2_knockdown_157_GSE34769	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.61917
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TE-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE78199_0_v_3_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K35222206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12034
GSE137144_5_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Weight Loss	CTD Gene-Disease Associations	1.0	1.33612
LAMTOR3	Pathway Commons Protein-Protein Interactions	1.0	null
BMI1-19503595-MEFSC-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
inferolateral temporal cortex (area TEv, area 20)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.51647
GSE115363_1_v_5_esrrb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Latex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.491
GSE157609,GSE158123_0_v_1_ifi16_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K20745677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.19657
ELMO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00669127
FLII	Pathway Commons Protein-Protein Interactions	1.0	null
TUBGCP2	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.2501
Prostate adenocarcinoma_PRAD_TCGA-J4-A67M-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
retropontine reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10464
GSE230656_0_v_1_gsdmd_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
EGR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.7893
GSE226285_3_v_1_nr0b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RAB9A	Pathway Commons Protein-Protein Interactions	1.0	null
Pigment granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.371
ILK	Pathway Commons Protein-Protein Interactions	1.0	null
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04292
H3K27ac_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCFC1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K00323141	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16912
RXR-22158963-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
supraoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.43248
SEPT2	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43373
BRD-K84636055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21717
BRD-A85860691_chaetocin_NCIH1694_6.0_h_0.08_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cytoplasmic vesicle membrane	GO Cellular Component Annotations 2015	1.0	null
EHD4	Pathway Commons Protein-Protein Interactions	1.0	null
PMC12913833-12672_2026_4481_MOESM3_ESM.xlsx-Table_S1-Table_S1_Two-sample_MR_analysis_of_blood_eQTLs_associated_with_LUAD_P_0_05_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01776
15486232-Table1	GeneSigDB Published Gene Signatures	1.0	null
CRCGN015_HEPG2_48H:E14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06709
H3K4me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-4448	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
molecular layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.30262
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hemophagocytic lymphohistiocytosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.00288
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.833671
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.838667
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
basolateral amygdaloid nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.89417
Perturb_17262_OE_Foxj2_SRP368260	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.1841
BRD-K47271260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23293
PMC5918774-13287_2018_864_MOESM2_ESM.xls-sheet-hREPC_AND_AF_MSC_AND_UM51_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-4A-A93Y-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAX5	ENCODE Transcription Factor Targets	1.0	null
BRD-K35520972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79145
DC-51-WE27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.322371
OTX2_KO_GSE27630_51_mouse_brain (fourth ventricular choroid plexus, E13)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CTCF_fibroblast of pulmonary artery_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RHOF	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K78866450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99168
GTEX-WOFM-1326-SM-3MJFR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14215
SYK	Pathway Commons Protein-Protein Interactions	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33872
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEL-HO	GDSC Cell Line Gene Expression Profiles	1.0	1.57931
VPS29	Pathway Commons Protein-Protein Interactions	1.0	null
OSBPL3	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_56_OE_Pias4_SRP183477	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-15.6063
abnormalities of the peripheral arteries	GWASdb SNP-Phenotype Associations	1.0	0.208995
CREB1-26743006-CHIP-SEQ-LNCAP-ABL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
superficial stratum of r1BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.59509
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00174
GATA3_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TP53	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K71472853	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92239
pyrophosphatase activity	GO Molecular Function Annotations 2015	1.0	null
BRD-K34445094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01315
FBXO22	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00574429
PVR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00587849
ZNF582	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75244
GATA-1_KD_GDS1245_81_mouse_megakaryocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SOAT2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00541929
GSE96649_1_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
A2780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01266
GTEX-NL3H-0011-R1a-SM-48TDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14566
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053106
BRD-K09854848_-666_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE203429_0_v_1_angptl8_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K57244822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04362
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PPP1CA	Pathway Commons Protein-Protein Interactions	1.0	null
HH	GDSC Cell Line Gene Expression Profiles	-1.0	-1.50482
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PMC8554124-DataSheet2.XLSX-57-CEBPD_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
GATA3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TYK-nu	GDSC Cell Line Gene Expression Profiles	-1.0	-1.50902
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.395205
SP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	125.8
SNX4	Pathway Commons Protein-Protein Interactions	1.0	null
GSE148692,GSE148695_7_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.53958
BC-00-YH62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.625295
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39657
AC-28-RT00_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.297445
PMC8260656-41467_2021_24380_MOESM4_ESM.xlsx-ERG_EZH2-ATTENUATED_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
disease	GWASdb SNP-Disease Associations	1.0	0.040497
DOCK5	Pathway Commons Protein-Protein Interactions	1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.87126
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K52838863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53023
r7 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56866
RBL1_KO_GDS1931_740_mouse_Neurospheres (MG-430A)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-T6MN-0011-R11A-SM-32QOX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71654
GTEX-S32W-0926-SM-4AD5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874589
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6325-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUZ12	ChEA Transcription Factor Targets	1.0	null
BRD-K57169635_dacomitinib_HCC515_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
tyrphostin AG-825-1114	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KLRC4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00521503
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07603
BRD-K84761515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1654
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.951208
Perturb_11746_KO_Mek2_SRP321493	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.82697
GTEX-UJHI-0826-SM-4IHLM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06717
PMC9746818-jciinsight-7-152886-s077.pdf-17-CEBPD_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.223
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_AA_NP-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10274745-media-4.xlsx-S3B-Table_S3_Reanalysis_of_publicly_available_data_to_identify_AR_and_ER_direct_target_genes_related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE146840,GSE146842_0_v_2_qrich1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910361
PMC7435699-mmc5.xls-Gene_lists-MITF_ChIP_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE175787_5_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K86574132_-666_VCAP_6.0_h_48.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GAS7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00567154
TXNRD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00400926
Liver Diseases	CTD Gene-Disease Associations	1.0	1.38946
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YO-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anterior olfactory nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57093
GSE196117_1_v_8_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNX7	Pathway Commons Protein-Protein Interactions	1.0	null
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.166998
rnf2_20805357_u2os_osteosarcoma_lof_human_gpl570_gse23035	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.075408
GTEX-QDVN-2326-SM-2S1PF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965035
HCT-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.881093
COV362_OVARY	CCLE Cell Line Proteomics	1.0	3.19234
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.901488
GSE184892_7_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.217346
Kidney Chromophobe_KICH_TCGA-KO-8405-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA3-27048872-CHIP-SEQ-THYMUS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBX4-33478486-IMR90-HUMAN-LUNG	ChEA Transcription Factor Targets 2022	1.0	null
GSE203485_1_v_0_sunitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
vitamin c_homo sapiens_gpl570_gse11919	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-R55G-0826-SM-2TC5U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949888
PMC7445411-CPR-53-e12862-s006.xlsx-Sheet1-Supplementary_Table_S4_Gene_expression_profiling_of_NT-MSC_and_III-MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K78385490_-666_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE164483_2_v_0_venetoclax_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
QF-00-NO42_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.265544
USF1_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K53972329_CT-INCB_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
external part of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50567
stratum lacunosum-moleculare of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.950984
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	1.0	2.97671
BRD-K52424224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33574
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Change_in_both_CSDE1_KD_hESCs-hgnc_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
mammillary area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08415
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-ensembl_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_GSK1070916_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00911908
UF-27-HS98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.478532
BRD-K04562748	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60971
outer CP in (rostral) midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00998
GTEX-OIZG-1326-SM-2HMIQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16046
ATP1A4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00506221
NCI-H1155	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.837522
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EM-01A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8185471-mmc4.xlsx-D4-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_4_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_7057_KO_Sod2_ERP107154	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.87034
CEBPD_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QCQG-0226-SM-48U28	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983959
JUN	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K07361992	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07863
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.409606
TRAPPC5	Pathway Commons Protein-Protein Interactions	1.0	null
SKBR3	DepMap CRISPR Gene Dependency	1.0	2.36681
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K57011718_UK 356618_PL21_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE213588_8_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RHEBP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00555211
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular homeostasis	GO Biological Process Annotations 2015	1.0	null
TPM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00675113
MPZL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53388
shell part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21884
BRD-K92372829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37639
RHOT1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QLQW-1326-SM-2S1QS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50855
hsa-miR-548c-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GTEX-XBED-0826-SM-47JYC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10892
CRCGN017_MCF10A.TP53.M_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10131
GSE164529_0_v_3_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
OBF-1_NULL MUTATION_GDS3473_571_mouse_Bone marrow pre-BII cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE149943_1_v_0_cd8a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE124410_6_v_0_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-MB-A5Y9-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SIU7-0226-SM-4BRX2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06028
BRD-K83289131_CAY10618_PL21_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FOXA2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K61124142	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9319
lateral nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.32573
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.842892
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_241_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
skin_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.56284
GTEX-R55F-1226-SM-2TF59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31465
YIF1A	Pathway Commons Protein-Protein Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A3YO-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K82019575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12649
SOX2-30713093-EPITHELIAL-HUMAN-TONGUE-SCC	ChEA Transcription Factor Targets 2022	1.0	null
GSE184356_1_v_2_tfam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199606_3_v_0_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMF1	Pathway Commons Protein-Protein Interactions	1.0	null
Vesicle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.502
ChIP_K27me3_17603471_mouseNPC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
RAW-264.7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.41
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A69I-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1298
single-organism organelle organization	GO Biological Process Annotations 2015	1.0	null
ARHGEF2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K17606413	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5817
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.327
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.57031
BRD-K72414522_AZD-5438_HA1E_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
GSE76771_1_v_3_atf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
membrane organization	GO Biological Process Annotations 2015	1.0	null
BRD-A47829399_artesunate_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE146982_0_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.36569
SCRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28908
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.927788
r7 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52256
GTEX-WL46-0011-R11A-SM-3MJFT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30571
BRD-K64800655_PHA-793887_HS578T_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
JHUEM7	DepMap CRISPR Gene Dependency	1.0	4.71802
GTEX-SE5C-0526-SM-2XCE1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82414
LEMD3	Pathway Commons Protein-Protein Interactions	1.0	null
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.220321
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.76054
BRD-K06500446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24803
BRD-K50157358	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45236
paracentral lobule, posterior part, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.06213
phagolysosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.313718
GSE144838_2_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB7A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1463
melanosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.219265
leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.0711
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15823
ATP6V1H	Pathway Commons Protein-Protein Interactions	1.0	null
Carcinogenesis	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K72034944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20372
GSE186810,GSE186813_7_v_5_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE133927_1_v_3_meox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PTPN9	Pathway Commons Protein-Protein Interactions	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A6C6-01A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organelle part	GO Cellular Component Annotations 2015	1.0	null
guanyl ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.049016
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.12
GSE149903_5_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE241036_0_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSK3A_knockdown_201_GDS4305	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.44983
GSE154936_3_v_2_remdesivir_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TBC1D4	Pathway Commons Protein-Protein Interactions	1.0	null
MAPK8	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_6388_KO_Mettl3_SRP254797	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GTEX-T6MN-0011-R4A-SM-32QPG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32513
BRD-K58137366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12676
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.30783
ROCK1	Pathway Commons Protein-Protein Interactions	1.0	null
IZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07326
BRD-A11702965_230752_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KDM6B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00451457
igr39	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.516
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVN-0526-SM-48TZ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21407
VAPA	Pathway Commons Protein-Protein Interactions	1.0	null
H1_Derived_Neuronal_Progenitor_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.33013
AP3D1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4PP-0926-SM-48TBZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883209
H3K4me3_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Phagocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.54
SUM102PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.75977
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A3F2-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adrenal Gland	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.742302
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-3.55946
Lateral amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40567
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-gene_id_y_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
trunk	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE183113_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82426
CNOT3	ChEA Transcription Factor Targets	1.0	null
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063896
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00819
496100654_HIP_no dementia_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0036
SEPT10	Pathway Commons Protein-Protein Interactions	1.0	null
ATP6V1C2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE151612_4_v_7_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PPARG-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
prednisolone-7424	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
zaprinast-1611	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VPS28	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K51791049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01356
superficial stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37696
BRD-K43069600_12K-516S_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cervical cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.106463
immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042427
SCYL1	Pathway Commons Protein-Protein Interactions	1.0	null
2203_DHX15_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.533905
H-7-5968	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
8-azaguanine-1791	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Temporal association areas, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42056
0175029-0000-6875	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GE-53-SM76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202824
SOX17-20123909-XEN-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K37764012_PF-3758309_HEPG2_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE248045,GSE248046_4_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PU.1-20176806-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
secondary lysosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.183631
abnormality of thyroid physiology	GWASdb SNP-Phenotype Associations	1.0	0.39507
GSE149035_3_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K50445566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61808
GSE213588_10_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K32862383	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56124
LYL1-30185409-K562-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
KYSE-180	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
GTEX-UJMC-2026-SM-3GADR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931945
IRF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE223008_0_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GTEX-U3ZM-0526-SM-4DXTB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06069
GTEX-OHPN-0011-R11A-SM-2I5FM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06923
HCC33	CCLE Cell Line Gene CNV Profiles	1.0	1.81867
GSE168076,GSE168080_1_v_0_batf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K22308901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5498
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A3-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUN-27471255-CHONDROCYTES-MOUSE-RIB	ChEA Transcription Factor Targets 2022	1.0	null
endocytic vesicle	GO Cellular Component Annotations 2025	1.0	null
ChIP_NANOG_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PTPN12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00455197
ChIP_EZH2_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
AICD_Induced  expression / Over-expression_GDS1979_288_human_SHEP-SF neuroblastoma	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K03654379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5747
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AC11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00535245
GTEX-XV7Q-0226-SM-4BRVL	GTEx Tissue Sample Gene Expression Profiles	1.0	2.73845
hsa-miR-4526	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837662
GTEX-X4XY-0526-SM-46MW1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8062
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
FGD3	Pathway Commons Protein-Protein Interactions	1.0	null
LAMA2_Deficiency_GDS3371_595_mouse_Hind limb skeletal muscle (4-week old dy3K/dy3K animals)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE109913_1_v_2_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K29560103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11341
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	1.0	2.07117
BRD-K93788137_PF-431396_A375_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.0894
EHD1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE92457_7_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.04785
ATG3	Pathway Commons Protein-Protein Interactions	1.0	null
7504_RPS15_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.689018
LU-134-A	GDSC Cell Line Gene Expression Profiles	-1.0	-1.83205
MCF7_Tranylcypromine_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0147721
Amphisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.585
NPSR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00416158
layer 1 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.90425
anion binding	GO Molecular Function Annotations 2015	1.0	null
SKBR3	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.61736
ARAP3	Pathway Commons Protein-Protein Interactions	1.0	null
Respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
endocytic vesicle	GO Cellular Component Annotations 2015	1.0	null
Liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.174
Perturb_18097_OE_Ogt_SRP214154	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.24847
BRD-K41674016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76368
BRD-K12955049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5291
carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053989
ribonucleoside triphosphate phosphatase activity	GO Molecular Function Annotations 2025	1.0	null
GTEX-QDVJ-0926-SM-2I5FU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839468
GTEX-WZTO-2826-SM-3NM8P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43985
GTEX-X8HC-1626-SM-46MWE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35191
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K91003483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23302
BRD-K06177900	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04314
membrane-bounded vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
POLR2A	ENCODE Transcription Factor Targets	1.0	null
mRNA_ESX1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE158182_3_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
APOE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00334713
MRC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00495412
CBX2-27304074-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
RPS6KA1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NUP50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27982
Poisoning	CTD Gene-Disease Associations	1.0	1.57688
ECSIT	Pathway Commons Protein-Protein Interactions	1.0	null
SMARCB1	ENCODE Transcription Factor Targets	1.0	null
GSE223241_1_v_3_cdkn2a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23012
Brain - Putamen (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	1.0	0.870168
BRD-K15794956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3706
BRD-K36575476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18812
BRD-K09149805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04266
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.378976
GTEX-T5JC-0011-R11A-SM-32PMB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.84262
GTEX-RVPV-0011-R11A-SM-2TF6F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91036
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
7734_SEC13_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.596327
Sorting endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.945
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A197-06A-32R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
carbohydrate derivative binding	GO Molecular Function Annotations 2015	1.0	null
FOXA1-21915096-LNCAP-1F5-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE124410_2_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
parthenolide-5105	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75181
KDM5A	ENCODE Transcription Factor Targets	1.0	null
IRF9	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-W5WG-1626-SM-4LMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.928257
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.870938
GATA3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
p1 part of the substantia nigra reticulata	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47152
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE125403_3_v_6_venetoclax_human	RummaGEO Drug Perturbation Signatures	-1.0	null
16488994-SuppTable1a	GeneSigDB Published Gene Signatures	1.0	null
PMC12486367-Supplementary_Data2.pdf-488-ZNF445_ZNF445	Rummagene Transcription Factor Associations 2026	1.0	null
ChIP_NANOG_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K17675814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17711
CA-75-HA22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.960826
FOS	JASPAR Predicted Transcription Factor Targets	1.0	null
phagolysosome assembly	GO Biological Process Annotations 2025	1.0	null
HPAFII	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70572
BRD-K28467941	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57368
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.61423
Breast Neoplasms	CTD Gene-Disease Associations	1.0	1.28827
acute myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.159658
TWNK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1821
hematopoietic system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
CDC23	Pathway Commons Protein-Protein Interactions	1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042251
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11188
MYC-27129775-CHIP-SEQ-CORNEA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
transport	GeneRIF Biological Term Annotations	1.0	null
HCC1187	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.8288
GSE161846,GSE161849_1_v_0_smarca4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Agranular insular area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.07254
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	1.0	2.5201
GTEX-WFON-2326-SM-3LK7M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17254
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LIN7C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1589
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.26008
THAP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0308
COLO679_SKIN	CCLE Cell Line Proteomics	1.0	8.83872
NAMALWA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04956
BRD-K78249980	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57134
CLTA	Pathway Commons Protein-Protein Interactions	1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HAND1_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K99749624_linifanib_MCF10A_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A1H6-01B-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7062471-elife-52504-supp6.xlsx-TEAD4_motif_in_OCR_around_DEGs-Gene_ID_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
RHOA	Pathway Commons Protein-Protein Interactions	1.0	null
EXOC1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN016_MCF10A.WT.HP_24H:D20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.08404
EGR1-23403033-LIVER-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE138872,GSE138874_0_v_1_il33_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_3017_KD_Ttn_SRP222910	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.65994
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TI-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nucleus of the lateral lemniscus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10148
skin	HPA Tissue Gene Expression Profiles	-1.0	-1.25449
NCIH446	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77997
NR4A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00621819
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01266
endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.13878
PMC8755441-mmc3.xlsx-IRF7-Up-SUZ12_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
COLO 678	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.901173
SNU886	DepMap CRISPR Gene Dependency	1.0	6.75676
GSE110178_5_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RWS6-0826-SM-47JXF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.920419
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A8YF-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
polymorph layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09278
MCM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00671271
layer 6b of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28615
Orbital area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5004
cuneate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.955825
GTEX-S7SE-0011-R11A-SM-2XCDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.59709
Prostate adenocarcinoma_PRAD_TCGA-J4-A67S-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Saos-2	GDSC Cell Line Gene Expression Profiles	-1.0	-2.94181
KNTC1	Pathway Commons Protein-Protein Interactions	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A82E-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
19797726-SuppTable1b	GeneSigDB Published Gene Signatures	1.0	null
4944_MED21_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.567282
CTCF_foreskin fibroblast_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1793_LUNG	CCLE Cell Line Proteomics	1.0	6.71477
BRD-K40738002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.42099
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CACNG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00669607
SP4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
establishment of localization	GO Biological Process Annotations 2015	1.0	null
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BD-61-OO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.412254
GTEX-R55E-0011-R4A-SM-2TC5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04961
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.18823
BRD-K52208857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80731
Prostate adenocarcinoma_PRAD_TCGA-CH-5744-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Golgi apparatus	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6N0-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Endomembrane system	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.502
CTSA	Pathway Commons Protein-Protein Interactions	1.0	null
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28795
CTCF_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SG in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.50989
GTEX-N7MS-0011-R5a-SM-2HMK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05955
arcuate nucleus of medulla, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.3006
GSE148066,GSE157787_3_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE127970_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QDVN-1626-SM-48TZC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33867
BC-54-ON71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.259425
CTCF	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6961-01A-21R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100622_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.66891
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.37433
WLS	Pathway Commons Protein-Protein Interactions	1.0	null
LANCL1	Pathway Commons Protein-Protein Interactions	1.0	null
CAVIN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00525523
OCT4_KD_GDS1824_135_mouse_embryonic stem (ES)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S2.xlsx-S2B_in_vivo_shared-Suppl_Table_S2B_shared_genes_between_RCAS-YAP1-MAMLD1-dR3R1_RCAS-YAP1-FAM118B_RCAS-YAP1-TFE3_in_vivo_tumors_RCAS_mouse_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE171712_0_v_1_scgb1a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
m1Lim part of the midbrain reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29685
GSE186660_2_v_1_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMAD4	ChEA Transcription Factor Targets	1.0	null
SNAP23	Pathway Commons Protein-Protein Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JH-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CA46	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54845
GSE188870,GSE188871_1_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K60918542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39931
PEO4	DepMap CRISPR Gene Dependency	1.0	5.54412
retrosplenial cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2756
TFAP2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	169.478
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC5637904-PATH-243-193-s016.xlsx-human_down_in_fat_SOX11-Table_S5C_Downregulated_genes_in_tumours_from_DCIS-SOX11_cells_compared_to_DCIS-lacZ_cells_injected_into_mammary_fat_pad_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
Adenocarcinoma	CTD Gene-Disease Associations	1.0	1.53579
GSE148262,GSE150691_1_v_2_hdlbp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9218776-ADVS-9-2104640-s002.xlsx-SIM_-_Nurr1-Unnamed_1_SIM2	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH1341	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63775
KLC1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K48389518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24793
EOMES	ChEA Transcription Factor Targets	1.0	null
GSE217156_2_v_3_trpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CHN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03241
BRD-K88080911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24794
NFIC_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.95091
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.93579
SLC18A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00477525
GSE169152_5_v_6_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SEC61G	Pathway Commons Protein-Protein Interactions	1.0	null
SNX27	Pathway Commons Protein-Protein Interactions	1.0	null
GSE202434,GSE202438_15_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A52893269	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15301
CHMP6	Pathway Commons Protein-Protein Interactions	1.0	null
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.4429
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.285316
MTA3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RECQL5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00961106
BRD-A68739437_NPK76-II-72-1_PC3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
nimesulide-1428	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K05753543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12521
REST_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kdm1a_KD_GDS5055_275_mouse_3T3-L1 preadipocytes - 48h	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SNU-601	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.3201
MRPL50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64013
EGR1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CL-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.16843
NAPA	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JF-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7898758-40168_2020_994_MOESM4_ESM.xls-PRDM15_target_genes-Gene_PRDM15	Rummagene Transcription Factor Associations 2026	1.0	null
SW948	GDSC Cell Line Gene Expression Profiles	1.0	2.15843
GSE239541_11_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE223008_7_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_3070_KO_Asb15_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.29329
periventricular stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07884
GSE128232,GSE128233_1_v_0_phf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
medial part of r8B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0373
LDLRAD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0065835
TXNDC12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00509346
RALB	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of LPrP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.77984
Infertility, Female	CTD Gene-Disease Associations	1.0	1.41229
GSE223008_4_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QCQG-1926-SM-2S1PI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17616
hsa-miR-4662a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
SPI1-22790984-ERYTHROLEUKEMIA-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
SP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43119
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.862971
BICR 22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34307
SYT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00634503
GRTP1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC12337709-mmc3.xlsx-Wild-type_vs_RAG1_KO_spleen-Unnamed_1_RAG1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K44950949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81225
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02583
GTEX-SNOS-1626-SM-3NMA4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900488
GSE100528_1_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A28105619_curcubitacin I_U937_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
4-P-PDOT	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57475
phagosome-lysosome fusion	GO Biological Process Annotations 2023	1.0	null
GTEX-WHSB-1326-SM-3LK6W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48415
GPRC5A	Pathway Commons Protein-Protein Interactions	1.0	null
FOS	ENCODE Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IG-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LRBA	Pathway Commons Protein-Protein Interactions	1.0	null
697 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.011
Perturb_65_KO_Cabin1_SRP252595	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.6536
abnormality of nervous system morphology	GWASdb SNP-Phenotype Associations	1.0	0.111562
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
stimulates	GeneRIF Biological Term Annotations	1.0	null
GTEX-X4XX-2926-SM-3NMB1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41631
PLEK2	Pathway Commons Protein-Protein Interactions	1.0	null
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052068
AML193	CCLE Cell Line Gene Expression Profiles	1.0	1.47555
Glaucoma_Retina_GSE3554	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.29305
GSE233049_2_v_0_atf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K18197334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.28335
HOOK2	Pathway Commons Protein-Protein Interactions	1.0	null
PRKAG1	Pathway Commons Protein-Protein Interactions	1.0	null
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3049
RAB18	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.878108
episupraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8969
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BS-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	119.897
intracellular ph reduction	GO Biological Process Annotations 2015	1.0	null
GTEX-WZTO-0011-R6B-SM-4E3J6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0318
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUT-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EGR1	ENCODE Transcription Factor Targets	1.0	null
GCSH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00494928
SU-DHL-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.13552
GTEX-V1D1-1026-SM-4JBHE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.950174
GSE202434,GSE202438_13_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cytoplasmic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.329837
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE138818_2_v_0_nanog_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE114883_1_v_4_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZFP281-18757296-E14-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.301
GSE148066,GSE157787_3_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TCF3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RANGAP1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE111035,GSE111040_10_v_9_plag1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149075_8_v_5_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EF-74-KW12_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227874
ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
MS4A10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00490093
TEF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0076227
GTEX-WVLH-0011-R5A-SM-3MJFW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16523
GSE135514_8_v_6_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MF-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RNOR-0011-R7A-SM-2TF4V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48844
AK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00660986
abnormality of the cerebral subcortex	GWASdb SNP-Phenotype Associations	1.0	0.357923
PMC6167382-41467_2018_6258_MOESM4_ESM.xlsx-TEAD-associated_GSC-Specific_UP-Nearest_Ensembl_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
GATA2-21666600-HMVEC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Crus 2, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5218
TCFAP2C-20176728-TROPHOBLAST-STEM-CELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_KLF4_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me1_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-2576-01A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.20554
spleen	GTEx Tissue Gene Expression Profiles	1.0	1.43155
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE151782_1_v_5_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE126776_0_v_1_pelp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MYC_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12703482-AMS-21-5-213605-s2.xlsx-Supplementary_Table_SXVI-SMR_results_of_expression_levels_of_VDR_target_genes_in_peripheral_blood_and_risk_of_prostate_cancer_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
RAB5B	Pathway Commons Protein-Protein Interactions	1.0	null
STX5	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2709-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Diarrhea	CTD Gene-Disease Associations	1.0	1.25868
GSE203158_0_v_14_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
layer 3 of LPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85944
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.89719
Perturb_5752_KO_Apoe_SRP115310	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.73047
GTEX-Q2AG-0011-R1A-SM-2HMJI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26029
Kidney renal papillary cell carcinoma_KIRP_TCGA-2K-A9WE-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.850264
superficial stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.44595
GSE228894_3_v_2_rnmt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kinetoplastid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.886
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
GSE148066,GSE157787_11_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PWOO-0726-SM-2I3EB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16186
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
rofecoxib-166	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_8361_KD_STAT3_SRP372295	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_5353_KO_Dux_SRP201141	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.23842
MAP2K4	Pathway Commons Protein-Protein Interactions	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A110-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.048385
TP63	JASPAR Predicted Transcription Factor Targets	1.0	null
YY1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.15626
chr13_110541325_G_A_b38	GTEx eQTL 2025	1.0	1.72718
GSE129241_4_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
IRF4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00625464
intermediate stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01785
Perturb_10416_KO_ZFP91_SRP315744	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.9906
GSE217776,GSE217829_1_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	1.0	null
WASL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00750563
GSE135514_8_v_9_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KHDRBS1	Pathway Commons Protein-Protein Interactions	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A5R1-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE206516,GSE206518_1_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Endocrine system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.983
superficial stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70199
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TMZS-0326-SM-3DB9P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31304
cefprozil	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08928
hsa-miR-4431	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
guanabenz-1961	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-RUSQ-0626-SM-2TF5V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33062
MCF7_CEP-33779_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0148242
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I4-11A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
16166195-TableS1a	GeneSigDB Published Gene Signatures	1.0	null
GSE258991_5_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPARG	ChEA Transcription Factor Targets	1.0	null
FOXO1-25302145-T-LYMPHOCYTE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ZBTB7A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KB-46-EJ60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.340946
BRD-A79768653_sirolimus_PC3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE87617_1_v_0_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:G24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5059
RAB43	Pathway Commons Protein-Protein Interactions	1.0	null
ChIP_PHC1_16625203	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-RU72-0011-R6A-SM-2TF71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.925718
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01181
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
QGP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35268
BRD-K24681473_S1130_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SLC30A9	Pathway Commons Protein-Protein Interactions	1.0	null
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.31372
PMC7918644-LSA-2020-00974_TableS2.xlsx-5_SAd2_BD_D-GATA3_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
GOT2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00593622
BRD-K85887470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51161
Lung squamous cell carcinoma_LUSC_TCGA-66-2756-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE220520_5_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TCF12	ENCODE Transcription Factor Targets	1.0	null
GSE137144_5_v_7_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HBEGF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00543814
BRD-K88448214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96604
GTEX-RN64-0326-SM-2TC5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0572
TPP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00615884
Oligospermia	CTD Gene-Disease Associations	1.0	1.22436
Retrosplenial area, ventral part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08617
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54G-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A110-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adenoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.946
PF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0181
PMC8494348-pone.0257161.s002.xlsx-D20-NOT_ext_ext-NOT_ext-Gene_Name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
RHOV	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00498717
CRCGN015_MCF10A.WT.HP_24H:P15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.17401
precuneus, left, superior lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.840791
MYOF	Pathway Commons Protein-Protein Interactions	1.0	null
protein transport	GO Biological Process Annotations 2025	1.0	null
BT549	DepMap CRISPR Gene Dependency	1.0	4.83126
GSE142210_3_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WZTO-0011-R4A-SM-3NMC7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10323
BRD-K94344573	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1174
GTEX-T2IS-3026-SM-32QPM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56866
hypoglossal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.863065
SNU1033	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59447
layer 2 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41427
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r6 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30829
H3K27ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KIAA0196	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K56716645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47826
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A498	GDSC Cell Line Gene Expression Profiles	1.0	1.76133
CREB1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETS1-21867929-TH2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
RREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	156.818
PLB985	Achilles Cell Line Gene Essentiality Profiles	1.0	1.57787
GSE214823,GSE214824_6_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10823279-CAS-115-283-s001.xlsx-Table_S5-Table_S5_List_of_188_genes_particularly_up-regulated_by_AR_in_AILNCaP14_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T8EM-0006-SM-3DB71	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31188
morphological abnormality of the central nervous system	GWASdb SNP-Phenotype Associations	1.0	0.126043
TRIM28-17542650-NTERA2-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUW1-0005-SM-4BOQ7	GTEx Tissue Sample Gene Expression Profiles	1.0	2.12448
GTEX-N7MS-2526-SM-2D7W3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79942
STK35	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00809752
KDM1A	ENCODE Transcription Factor Targets	1.0	null
AP1S1	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27ac_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
purine ribonucleoside binding	GO Molecular Function Annotations 2015	1.0	null
MVB12A	Pathway Commons Protein-Protein Interactions	1.0	null
DK-MG	GDSC Cell Line Gene Expression Profiles	-1.0	-1.43789
CHD1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.11423
GSE110178_5_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Piriform-amygdalar area, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39212
CEBPB	JASPAR Predicted Transcription Factor Targets	1.0	null
TRAPPC3	Pathway Commons Protein-Protein Interactions	1.0	null
NR0B1-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ETS1	ENCODE Transcription Factor Targets	1.0	null
subbrachial nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59436
CHRNB3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00629795
salivary gland	HPA Tissue Protein Expression Profiles	1.0	0.78613
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.23634
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
CHRM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00550411
Anterior cingulate area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40589
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00264
PHC1-16625203-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K87947369_VX-680_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WVLH-0011-R11A-SM-3MJFO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.07268
inferolateral temporal cortex (area TEv, area 20)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02209
GTEX-WFON-2126-SM-3LK7O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.967061
PMC8851354-Table_6.xlsx-Ruxolitinib_reg_STAT3-bound-Supplementary_Table_6_Genes_regulated_by_ruxolitinib_that_are_STAT3_targets_in_at_least_two_cell_lines_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K99660943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2548
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K94744294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09949
Urinary Bladder Neoplasms	CTD Gene-Disease Associations	1.0	1.32846
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.10973
GSE127790_6_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular pH reduction	GO Biological Process Annotations 2023	1.0	null
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.353485
KA-81-AG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.362601
H3K9ac_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
raubasine-6360	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ISL1-27105846-CHIP-SEQ-CPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1-23547873-NB4-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
NPAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70262
GTEX-PSDG-1626-SM-48TCQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13368
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KLF4-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JG-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE164874_5_v_10_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
vesicle fusion	GO Biological Process Annotations 2015	1.0	null
CDC42BPB	Pathway Commons Protein-Protein Interactions	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K17303020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76641
ATP6V1D	Pathway Commons Protein-Protein Interactions	1.0	null
SNX15	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K02822062_CT-200783_NCIH1694_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE179974_3_v_0_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K37720887_SB-525334_MCF7_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052404
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A1-11A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_1512_KO_Ash2l_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.34798
GOSR1	Pathway Commons Protein-Protein Interactions	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.45126
GSE202587_1_v_0_xrn1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.96709
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
PPARG-20176806-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HMCN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00613251
ALDH1A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00555072
Thyroid adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.253
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K78828094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04216
GTEX-WZTO-0011-R7B-SM-4E3IS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860244
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826886
hsa-miR-3163	TargetScan Predicted Conserved microRNA Targets	1.0	0.193083
Optic ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.72
TSPYL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08779
RNF2	ChEA Transcription Factor Targets	1.0	null
IL13RA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00560568
GTEX-N7MT-1426-SM-3LK5M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878828
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LMBR1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07086
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6747431__F5	PFOCR Pathway Figure Associations 2024	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05141
STAT5A	Pathway Commons Protein-Protein Interactions	1.0	null
MCF7_PFI-1_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0141061
GTEX-PVOW-2626-SM-32PL8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.8107
posterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.865964
GTEX-PLZ5-0326-SM-3P614	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19317
BRD-K12513721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25046
BRD-K08829593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18886
UBTF_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SEC22B	Pathway Commons Protein-Protein Interactions	1.0	null
GSE183327,GSE183328_1_v_0_ddit3_human	RummaGEO Gene Perturbation Signatures	1.0	null
AM38	DepMap CRISPR Gene Dependency	1.0	2.18871
GTEX-SNOS-1726-SM-32PLN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864621
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
lung	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TCN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00793898
PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-HIF1_HIF2_miRNA_targets_hyp-Unnamed_16_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
raubasine-1748	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
neurodegenerative disease	GWASdb SNP-Disease Associations	1.0	0.244132
shoot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.086563
NCIH889	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62719
GSE101239_4_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ribonucleoside binding	GO Molecular Function Annotations 2015	1.0	null
GSE152441,GSE152442_7_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AP3M1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22747
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02665
Anorexia	CTD Gene-Disease Associations	1.0	1.13621
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.894829
GSE169713,GSE169715_1_v_2_tert_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.73442
TFAP2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	138.184
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
COLO205	CCLE Cell Line Gene Expression Profiles	1.0	1.38796
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-11A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KAT2A	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41S-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of localization	GO Biological Process Annotations 2015	1.0	null
POLR2AphosphoS2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hematuria	CTD Gene-Disease Associations	1.0	1.23806
GTEX-QESD-1726-SM-2S1R7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877707
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2025	1.0	null
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXA1-26743006-CHIP-SEQ-LNCAP-ABL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0389
DB-21-FY75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.294082
GTEX-OIZH-1826-SM-2YUNP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894614
GTEX-PLZ4-1626-SM-3P618	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873796
H3K4me3_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E16_vs_E20_814_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5703-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN013_HEPG2_24H:F18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06309
CRCGN015_HEPG2_48H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.09587
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.72286
17483317-TableS4	GeneSigDB Published Gene Signatures	1.0	null
GTEX-O5YT-0526-SM-32PK8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24493
VANGL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00648876
SEC31A	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4160-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN010_HEPG2_24H:L23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25216
NCI-H460	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.82254
outer portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.58647
TMEM230	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01567
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.8129
HOPS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.838
Anterior olfactory nucleus, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29269
SOX2-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
496100584_HIP_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.63643
phagocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.602331
TEK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00511109
striatum_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05111
SYN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00773143
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Decreased_in_both_CSDE1_KD_hESC-gene_short_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Erythema	CTD Gene-Disease Associations	1.0	1.11325
Thyroid stimulating hormone levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.804576
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RJ-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.01688
PMC3419980-leu201249x2.xls-RUNX1-ETO_siRE_ChIPSeq_peaks_ge-gene_name_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
cingulate gyrus, parietal part, left, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.87227
CKAP5	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN017_MCF10A.TP53.M_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.7651
GTEX-T2IS-0011-R11A-SM-32QPC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.16338
GSE116810_5_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A0VM-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Main olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.24691
Stomatitis	CTD Gene-Disease Associations	1.0	1.13279
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH2052	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.16966
H3K36me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Listeriosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fluorouracil	CTD Gene-Chemical Interactions	1.0	null
H3K4me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GATA2_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K22944782	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36063
Heart - Left Ventricle	GTEx Tissue Gene Expression Profiles 2023	1.0	1.91669
Anterior olfactory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33154
Brain - Cerebellar Hemisphere	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.875289
BD-96-HO33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.648399
GSE155031_5_v_3_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K49456190_PRIMA-1 MET_NCIH1694_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE210885_2_v_1_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HAUS3	Pathway Commons Protein-Protein Interactions	1.0	null
rMC-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.54
ARL6IP1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE246335_4_v_5_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-4666-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
BRD-K32862555_NCGC00183412-01_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KLF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	135.372
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.39284
Cystic Fibrosis_Intestinal Epithelium_GSE765	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	3.21115
GATA2	ChEA Transcription Factor Targets	1.0	null
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3665	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
FOXO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24332
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
imatinib_homo sapiens_gpl96_gds3044	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_14455_KO_Figla_SRP228490	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.1816
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.895977
POLR2A_GM12891_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Declive (VI), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20688
GATA3_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RARB-24833708-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CAMA1	DepMap CRISPR Gene Dependency	1.0	2.11706
GSE197555_0_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GPHN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00744677
DTNBP1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE179974_3_v_4_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-1224-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Tobacco Use Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-A16700644_ISOXSUPRINE HYDROCHLORIDE_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-T6MN-0526-SM-32PMS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903215
PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_downregulated-Gene_name_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
SP2509	DeepCoverMOA Drug Mechanisms of Action	1.0	0.92
BRD-K13336710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59329
LMBR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00645484
BRD-K08618283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22365
GSE133516_0_v_2_kat7_human	RummaGEO Gene Perturbation Signatures	1.0	null
CABLES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73805
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-V955-2426-SM-3GAEF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.962775
NDUFA12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00652545
EXPH5	Pathway Commons Protein-Protein Interactions	1.0	null
Anemia	CTD Gene-Disease Associations	1.0	1.15526
PRSS53	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00643669
gracile nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.23247
Liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.158
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SIGMAR1	Pathway Commons Protein-Protein Interactions	1.0	null
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.137
VEZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.3769
H3K27ac_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DLD-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.948963
ARHGAP17	Pathway Commons Protein-Protein Interactions	1.0	null
VCAP	DepMap CRISPR Gene Dependency	1.0	9.52485
PMC11285331-cd-23-0539_table_s1_suppst1.xlsx-Lost_AR_Peaks-Unnamed_20_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HS578T	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.08264
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12869
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PLZ5-1726-SM-2I5F6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.961044
LHX1_KO_GDS2748_298_mouse_embryonic renal vesicles	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A5RJ-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U8XE-0005-SM-3DB8I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75179
Phagolysosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.031
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Kidney Injury	CTD Gene-Disease Associations	1.0	1.31746
SNU668	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76807
ctnnb1_21914722_ls174t_lof_human_gpl570_gds4386	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.008751
BRD-K37387086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34123
BRD-K60507129	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08237
regulation of transport	GO Biological Process Annotations 2015	1.0	null
lysosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.185777
GSE197571_3_v_1_foxm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.047
GTEX-N7MS-0011-R6a-SM-2HMJ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05745
BRD-K20526256_HG-14-10-04_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-A24396574_celastrol_SKBR3_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SYT11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00582772
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.81332
H3K4me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPARG-20176806-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NANOG-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.25435
PMC5287225-supp_gr.209163.116_Supplemental_Table_S4.xlsx-Table_S4-Supplemental_Table_S4_Differentially_expressed_genes_related_to_ZNF384-rearranged_ALL_ZNF384	Rummagene Transcription Factor Associations 2026	1.0	null
SB-94-ZA83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.374674
layer 3 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10584
PMC7517358__F3	PFOCR Pathway Figure Associations 2024	1.0	null
HCT15	BioGPS Cell Line Gene Expression Profiles	1.0	0.879783
BRD-K53901855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99429
spleen	HPA Tissue Gene Expression Profiles	1.0	1.06023
Cortical amygdalar area, anterior part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.85475
superficial stratum of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49198
BRD-K38347298	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49136
LAMP3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0101163
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.824493
hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.050411
GSE223540_2_v_3_anxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
16417408-Figure4	GeneSigDB Published Gene Signatures	1.0	null
BRD-K57937572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57982
SNX9	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN015_MCF10A.WT.HP_24H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.47184
PMC7220941-41598_2020_64431_MOESM2_ESM.xlsx-WS2_2019_Affy_IDs_SignalsQN-Unnamed_2_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE223008_6_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K36me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LIVF001-005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21527
NLGN3_KD_GDS4759_336_mouse_E16 primary cortical neuron cultures	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5040-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040479
MAX_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JMJD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42749
GSE138050,GSE148257_1_v_2_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-8584-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cation homeostasis	GO Biological Process Annotations 2015	1.0	null
EE-98-PF86_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.290587
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.384
GSE118077_7_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC3510027__F2	PFOCR Pathway Figure Associations 2024	1.0	null
Bcl3/NF-kappaB2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.837
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.836888
SYNJ2BP	Pathway Commons Protein-Protein Interactions	1.0	null
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.62874
BRD-K63587749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16692
Ectorhinal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6511
Endopiriform nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18527
BRD-A67788537_Salermide_PC3_24.0_h_120.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC3435504-msb201237-s2.xls-Supp_Table_4b-CEBP_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.39865
BRD-K72467884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00826
4946_MED23_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.786488
ZNF384	ENCODE Transcription Factor Targets	1.0	null
regulation of ph	GO Biological Process Annotations 2015	1.0	null
TFDP1_02_71	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60942
BRD-A27640568_5846833_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPVG-0626-SM-4B65B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982813
Lung squamous cell carcinoma_LUSC_TCGA-22-5481-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SIU7-1126-SM-2XCDW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922396
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.31333
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TAGLN2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE231524,GSE231526_0_v_1_dusp6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Piriform area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40273
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69177
medial part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05271
chemical homeostasis	GO Biological Process Annotations 2015	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.7046
LSG1	Pathway Commons Protein-Protein Interactions	1.0	null
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.78606
GSE197571_2_v_1_foxm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CEBPB-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06455
LN319	Achilles Cell Line Gene Essentiality Profiles	1.0	1.17439
BRD-K22045035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02244
MS4A13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00435006
Organ system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.164
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_12hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE179974_3_v_5_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-A5HY-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.849756
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.08436
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0595
mediodorsal nucleus of thalamus_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.65231
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
7585_RTF1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.557413
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8429-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCAMP2	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN008_HEPG2_24H:J03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3685
SRMS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00417987
Perturb_13480_KO_Bmal1_SRP260650	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.69299
OXCT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00322268
lower (caudal) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.964426
GSE166944_3_v_2_eif4b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.928969
CYTH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00381564
BRD-K57014767	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4876
GSE199606_3_v_0_csf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A17X-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE130217_5_v_3_sesn2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
peri-centrosomal recycling endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.958
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.958755
ZWILCH	Pathway Commons Protein-Protein Interactions	1.0	null
AP2B1	Pathway Commons Protein-Protein Interactions	1.0	null
PHLDA3	Pathway Commons Protein-Protein Interactions	1.0	null
arcuate nucleus of medulla, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12416
phagosome acidification	GO Biological Process Annotations 2015	1.0	null
GSE184884_2_v_1_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CRCGN008_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.2281
SPI1	ChEA Transcription Factor Targets	1.0	null
alzheimer disease	GWASdb SNP-Phenotype Associations	1.0	0.472241
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6933-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Leukemialymphoblastic(MOLT-4)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.859564
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RADX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02145
MAFK	ENCODE Transcription Factor Targets	1.0	null
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13475
GSE158632_3_v_1_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XBED-1426-SM-4AT4G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901825
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.734304
RFC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23177
GSE94849_3_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-3656	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
KDM8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00412532
ACHN	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.62977
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE114284_4_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7517358__F3	PFOCR Pathway Figure Associations 2023	1.0	null
GTEX-X4EP-0326-SM-3P5Z6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923137
GTEX-Q2AG-0011-R6A-SM-2HML7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.881484
mantle zone of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03619
GSE205316,GSE205317_2_v_3_nrip1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.217693
TRAPP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.576
primary auditory cortex (core)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.876219
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01958
PHC1	ChEA Transcription Factor Targets	1.0	null
GBA	Pathway Commons Protein-Protein Interactions	1.0	null
ANGPTL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00511193
HM7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.998412
GSE158197_6_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH1355	CCLE Cell Line Gene Expression Profiles	-1.0	-1.8069
GSE146840,GSE146842_3_v_2_qrich1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-Q2AG-0011-R7A-SM-2HMJP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1666
hsa-miR-4668-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
KYSE520	DepMap CRISPR Gene Dependency	1.0	2.84704
tauopathy	GWASdb SNP-Disease Associations	1.0	0.55372
Heart Failure	CTD Gene-Disease Associations	1.0	1.07057
NCSTN	Pathway Commons Protein-Protein Interactions	1.0	null
primary visual cortex (striate cortex, area V1/17)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.60248
BRD-K47410882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01301
single-organism process	GO Biological Process Annotations 2015	1.0	null
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.837822
PSMB8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00374351
PROSER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21756
BRD-K13673722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51839
Perturb_10584_KO_Tbx5_SRP191501	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.32655
Adrenal cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.072
TFAP2E	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.8372
GSE140651,GSE140653_2_v_6_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.99761
pigment granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.200999
GTEX-QDT8-0006-SM-32PL3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49053
BRD-K34258763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03447
TBC1D23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05657
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.39768
JD-81-YX02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.752805
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
MVP	Pathway Commons Protein-Protein Interactions	1.0	null
PTBP1_02_131	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60786
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5698-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EGF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0184738
CRCGN010_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.40206
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56269
SRY	ChEA Transcription Factor Targets	1.0	null
SEPT9	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XUW1-0826-SM-4BOP6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.918478
P-loop containing nucleoside triphosphate hydrolase	InterPro Predicted Protein Domain Annotations	1.0	null
PMC11185762-media-2.xlsx-ATAC2wk_KD_V337M_intersect_peak-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN012_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.03786
BRD-A05565054_(2-ethylpiperidin-1-yl)(4-(hydroxydiphenylmethyl)-1H-1,2,3-triazol-1-yl)methanone_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
purine nucleoside binding	GO Molecular Function Annotations 2015	1.0	null
GSE174701_1_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
SW948	CCLE Cell Line Gene Expression Profiles	1.0	1.69325
periventricular stratum of isBI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00255
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A7U6-01A-12R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE127790_6_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8789288-elife-73137-supp3.xlsx-Gene_List_Comparisons-Supplementary_file_3_Comparison_of_genes_induced_by_IRF1_or_IFNg_with_genes_in_the_type_II_ISG_screen_library_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_Jurkat_ChIP-seq_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
SW620	BioGPS Cell Line Gene Expression Profiles	1.0	1.40903
RL952	CCLE Cell Line Gene Expression Profiles	1.0	1.4071
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066448
GSE149075_2_v_5_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
u2197	HPA Cell Line Gene Expression Profiles	-1.0	-0.856619
LIN7C	Pathway Commons Protein-Protein Interactions	1.0	null
Hypothyroidism	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.983
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_10615_OE|KO_Stk4|Lgals3_SRP121622	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.20892
CBX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03345
Piriform area, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48881
Fibrosis	CTD Gene-Disease Associations	1.0	1.62803
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10U-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K82392710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50895
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MMUT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55151
EPRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06168
Disease Models, Animal	CTD Gene-Disease Associations	1.0	1.21173
ChIP_SOX2_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K25337138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57988
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA3-24758297-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CALM1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5KX-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K83902026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03976
GSE48812_2_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Agranular insular area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07353
intermediate stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10294
HT29	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.04105
BHLHE40_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
arteriosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.232925
GSE184892_0_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-PWCY-1926-SM-3NB25	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839092
H3K9ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K18178356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14846
cochlear nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.883959
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
small gtpase mediated signal transduction	GO Biological Process Annotations 2015	1.0	null
GSE101537_4_v_2_neurog3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COLO684	CCLE Cell Line Gene CNV Profiles	-1.0	-1.92479
RHOBTB3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0057227
MCF7_Cerdulatinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.014239
PAX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0041
Brain - Frontal Cortex (BA9)	GTEx Tissue Gene Expression Profiles 2023	1.0	2.88765
BRD-K96295480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22226
BRD-A75409952_wortmannin_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CHD7	ENCODE Transcription Factor Targets	1.0	null
cellular monovalent inorganic cation homeostasis	GO Biological Process Annotations 2015	1.0	null
ANXA9	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN009_HEPG2_24H:M19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.66
Simple lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21223
BRD-K60531990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.31713
adrenal gland	HPA Tissue Protein Expression Profiles	1.0	0.78613
Anterior olfactory nucleus, external part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.90144
tretinoin-6170	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC10679662-mmc2.xlsx-NC-D5-ZEB2-siRNA-Upregulated-Gene_Symbol_ZEB2	Rummagene Transcription Factor Associations 2026	1.0	null
POU5F1_01_05	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.3834
MTOR	Pathway Commons Protein-Protein Interactions	1.0	null
LARP4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69795
DMS79	CCLE Cell Line Gene CNV Profiles	1.0	1.46094
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLAGL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.51
NB69	DepMap CRISPR Gene Dependency	1.0	2.60665
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
Perturb_3088_KO_Fam210b_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.32705
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06677
PPP2R1B	Pathway Commons Protein-Protein Interactions	1.0	null
GATA2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10194
NCIH1105	CCLE Cell Line Gene CNV Profiles	1.0	1.42499
GSE210388_2_v_0_ror2_human	RummaGEO Gene Perturbation Signatures	1.0	null
phagolysosome assembly	GO Biological Process Annotations 2023	1.0	null
COLO668	CCLE Cell Line Gene CNV Profiles	1.0	1.53784
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12684
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE111035,GSE111040_3_v_13_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A69815203_CYCLOSPORINE_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CEBPB-20176806-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K21064560_PALDA_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
KMS12BM	Achilles Cell Line Gene Essentiality Profiles	1.0	1.29631
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02751
GTEX-XV7Q-0426-SM-4BRVN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04771
GTEX-QDVN-0726-SM-4B64L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01421
GSE179974_3_v_1_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE210870_0_v_2_snai1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78M-01A-21R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BE2M17	DepMap CRISPR Gene Dependency	1.0	2.36801
DA-20-VR86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.546094
GSE134375_4_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_16362_KD_VDR_SRP057721	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
CEBPA-26348894-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
COLO-704	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.55992
BRD-K72414522_AZD-5438_MCF10A_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Crus 2, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4003
ZBED4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	127.177
ARHGEF10L	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K30633507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98077
hsa-miR-3942-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
MTF2-20144788-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
15361855-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
BRD-K46494135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61218
methotrexate_homo sapiens_gpl570_gse11440	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Endopiriform nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11553
BRD-K42034238	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14311
BRD-K52911425_GDC-0941_A549_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Anterior cingulate area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.22521
Brain - Anterior cingulate cortex (BA24)	GTEx Tissue Gene Expression Profiles 2023	1.0	1.84188
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.42993
20101236-Table2	GeneSigDB Published Gene Signatures	1.0	null
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31401
GSE154464_1_v_2_cdk6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12623973-41467_2025_64981_MOESM3_ESM.xlsx-downregulated-c0_ACKR4_SCS_ceiling_LEC_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE240645_1_v_0_u90926_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
lytic vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.185777
ERMAP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00716797
Integral component of Golgi membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.169
subgranular zone of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25792
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
plicamycin_homo sapiens_gpl570_gse25127	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K82580504_-666_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-U412-0326-SM-3DB9L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832232
PMC5806898-pbio.2004411.s003.xlsx-MR_plot_data-Gene_names_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Piriform area, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29162
GSE172490_5_v_3_junb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE195514_0_v_1_stk25_human	RummaGEO Gene Perturbation Signatures	1.0	null
r4 part of descending trigeminal sensory nucleus, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.77155
GATA3_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12396377-jcb_202307079_tables1.xlsx-Fig_1C_i_-_iii_right-x_TFEB_KOcon_VS_WTcon_UP_TFEB	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QH-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DPH5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00459026
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AG-0011-R9A-SM-2HMJ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848932
IGLL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00471159
SCARB2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QVUS-2926-SM-3GIJB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20079
LIVF001-015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21921
GATA1-30185409-K562-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
GSE228413_4_v_3_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.66108
u26684	HPA Cell Line Gene Expression Profiles	-1.0	-1.04776
GSE232218_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE150669_2_v_3_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ChIP_RNF2_22325148	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Prostatic Neoplasms	CTD Gene-Disease Associations	1.0	1.01474
mood disorder	GWASdb SNP-Disease Associations	1.0	0.289486
GSE149075_6_v_4_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CCL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00582339
TAT protein transport complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.667
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07231
Early phagosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.953
ruffle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.25547
GTEX-XMK1-0126-SM-4B65F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871629
GSE201309_1_v_8_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.331719
Micropinosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.64
RAP1GDS1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE125014_6_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-IS-A3KA-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8201-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPI1-22790984-ERYTHROLEUKEMIA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
occipito-temporal gyrus, left, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.872238
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04969
EZH2	ChEA Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8083-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148321,GSE169423_2_v_1_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HS578T	CCLE Cell Line Gene CNV Profiles	-1.0	-1.79191
CTCF_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE203158_5_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.80209
CRCGN017_MCF10A.WT.HP_24H:F24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.18635
superficial stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08028
LAMB3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00496844
ENTHD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00434762
BRD-K03902789	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82437
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYOC_OE_GDS1640_269_mouse_retina	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28467
GSE99687_0_v_1_smad5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-Q2AG-0011-R4A-SM-2HMKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13601
LAMA2_Deficiency_GDS1778_747_mouse_Diaphragm (from dystrophia muscularis -dy/dy- mouse model)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CL-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05221
cytoplasmic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
TNFRSF13C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00551381
PMC7616765-EMS198548-supplement-Data_S2.xlsx-3_DEG_2D_and_3D-D9_Up_in_3D_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89723
PMC9950457-mmc3.xlsx-GRHL2_binding_sites-RBBP8NL_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE148066,GSE157787_9_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE235390_4_v_0_lurbinectedin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.836506
BRD-K65242613_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K54370483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19445
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.091
Skin Cutaneous Melanoma_SKCM_TCGA-RP-A695-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6451017-41598_2019_42107_MOESM11_ESM.xlsx-all_MYCN_as_effector_lincRNAs-mRNA_genes_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
GSE242367_1_v_0_dpp9_human	RummaGEO Gene Perturbation Signatures	1.0	null
lymphnode_5b	HPA Tissue Sample Gene Expression Profiles	1.0	1.22625
FABP4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00463786
HCK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0033591
chr13_110542505_T_C_b38	GTEx eQTL 2025	1.0	7.25477
ACKR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00579759
GTEX-WL46-0011-R7A-SM-3LK7X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10219
Head and Neck squamous cell carcinoma_HNSC_TCGA-RS-A6TO-01A-32R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_3068_KO_Apof_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.57309
BRD-K28455914	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0936
Perturb_3093_KO_H1foo_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.46765
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_5160_KO_Mettl3_SRP048598	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.39964
SP8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	108.459
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
rh30	HPA Cell Line Gene Expression Profiles	-1.0	-0.962775
cytoplasmic membrane-bounded vesicle	GO Cellular Component Annotations 2015	1.0	null
BRD-K39099034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33422
496100333_FWM_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.38382
COLO201	CCLE Cell Line Gene Expression Profiles	1.0	1.4459
FOXA1-25552417-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K23430114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35937
GSE247159_8_v_3_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
chlorphenesin-2115	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GOSR2	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A4XC-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AG-2926-SM-2HMJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30327
FOXO1-23066095-LIVER-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
7893_SEM1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.851605
L428	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38888
BRD-K57349002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45175
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
Tongue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.119
PYGB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00467684
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46829
GTEX-R55E-0011-R7A-SM-2TC5Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907399
BRD-K23867157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0729
BRD-K79202867	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18585
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K70161581_-666_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
VPS33B	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF263	ENCODE Transcription Factor Targets	1.0	null
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5531
GTEX-RVPU-0011-R7A-SM-2XCAB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876603
DMS53	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46672
PRR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15461
GTEX-Q2AG-0526-SM-2S1PW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35499
RPE1SS119	DepMap CRISPR Gene Dependency	1.0	2.34545
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
doxorubicin_homo sapiens_gpl570_gse46493	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE101767_1_v_0_wdr11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CREBBP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00649645
EFM192A	CCLE Cell Line Gene Expression Profiles	1.0	2.30991
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC10123531-NIHMS1874945-supplement-Table_S3.xlsx-SOX17_BCAT_cobound_coreg_peaks-Gene_Name_SOX17	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
EGR1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VPS45	Pathway Commons Protein-Protein Interactions	1.0	null
Neurodevelopmental disorder with microcephaly, epilepsy, and brain atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.544
ZNF213	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	98.6434
ZNF682	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.0028
dorsolateral prefrontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.35392
BRD-K69852452_7241-4207_SKB_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.880567
NB-58-SA13_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.302246
TRIM28_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDT8-3026-SM-32PKB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84423
CRCGN017_MCF10A.TP53.M_24H:P11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08552
MT-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.970905
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.29673
ENPP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00647033
CA7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00762504
MOSPD2	Pathway Commons Protein-Protein Interactions	1.0	null
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10186
blood cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062318
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.066532
Perturb_6299_KD_CGA_SRP355115	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
SPI1-23127762-K562-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE210580_5_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GNA11	Pathway Commons Protein-Protein Interactions	1.0	null
TRPC5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00612193
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EF-80-OD07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.290696
D-566MG	GDSC Cell Line Gene Expression Profiles	-1.0	-1.67523
GSE158197_2_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K51454923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65656
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
central nervous system disease	GWASdb SNP-Disease Associations	1.0	0.153254
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5182-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE96991,GSE97117_5_v_2_il11_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
REST_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE234155_7_v_1_nfix_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31449
BRD-K14000735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50452
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79393
DY 131	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.36
GSE95688_7_v_5_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE239541_5_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE166944_1_v_2_eif4b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Artery - Coronary	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.69621
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5022-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SEC61A1	Pathway Commons Protein-Protein Interactions	1.0	null
C4B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.009097
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bounding membrane of organelle	GO Cellular Component Annotations 2015	1.0	null
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
establishment of protein localization	GO Biological Process Annotations 2015	1.0	null
TBX20-22080862-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SMARCB1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:F13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.23045
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043169
NCIH522	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4564
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_12969_KO_PRMT7_SRP342313	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-RUSQ-1826-SM-2TF6E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930035
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.28395
vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.109662
Prostate adenocarcinoma_PRAD_TCGA-EJ-8472-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01217
GSE190316,GSE190324_10_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAFF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K82922770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76893
GSE242083,GSE242098_2_v_5_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GABRQ	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00768053
gata1_15860665_megakaryocytes_lof_mouse_gpl1261_gds1245	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.215497
STOML2	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-3158-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38994
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE171401_1_v_0_adnp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HIP1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QCQG-0326-SM-2I3ES	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869591
BRD-K45056520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56799
GTEX-XUZC-2026-SM-4BRW9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15348
Colorectaladenocarcinoma	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.04452
BRD-K26669427_WR 216174_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-6881-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular component organization or biogenesis	GO Biological Process Annotations 2015	1.0	null
superficial stratum of r3Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36546
PDE10A_KO_GDS4542_292_mouse_hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-A52530684_DOXORUBICIN_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67K-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cells - EBV-transformed lymphocytes	GTEx Tissue Gene Expression Profiles 2023	1.0	1.62427
RAB1B	Pathway Commons Protein-Protein Interactions	1.0	null
GSE145323,GSE145324_9_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FCMR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00476126
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.845991
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.981926
COG4	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K27331198	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26677
GSE111102,GSE111105_1_v_5_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CPC-N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ETS1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_1day-MOI-10^3_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.92114
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.93052
CEBPB_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53106
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
LS-513	GDSC Cell Line Gene Expression Profiles	1.0	1.64724
BRD-K29379705	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49167
GSE168602,GSE168604_2_v_6_selumetinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7925689-41467_2021_21687_MOESM10_ESM.xlsx-A_HIF1A-Unnamed_8_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
VPS39	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K31748787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39093
endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.050471
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
arcuate nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.99373
Brain Lower Grade Glioma_LGG_TCGA-FG-6691-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AP2M1	Pathway Commons Protein-Protein Interactions	1.0	null
caudal subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.00652
GSE149264,GSE149267_4_v_5_trp53_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_14133_KO|OE_Dnmt3a/Dnmt3b|Kdm4b|Kdm5b_SRP151021	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.59869
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.218
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-V1D1-0226-SM-4JBHG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64535
BUD23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32689
EIF3I	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26977
GADD45GIP1	Pathway Commons Protein-Protein Interactions	1.0	null
Thymus-macrophage	Tabula Sapiens Gene-Cell Associations	1.0	0.703804
PRKAA1	Pathway Commons Protein-Protein Interactions	1.0	null
ACSF2	Pathway Commons Protein-Protein Interactions	1.0	null
SNX12	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WQUQ-0006-SM-3MJF4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25225
POLR1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00714554
BRD-K93295557	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36112
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RING1B-27294783-CHIP-SEQ-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
STXBP2	Pathway Commons Protein-Protein Interactions	1.0	null
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.905774
POLR2AphosphoS5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer I of piriform cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35563
GTEX-P4QS-1626-SM-2S1NH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28691
leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.242983
BRD-K84936524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29251
NADSYN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00373695
VSIR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00464983
GTEX-P4QT-0526-SM-2I3EX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835306
Mueller cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.961
NCIH1836	CCLE Cell Line Gene CNV Profiles	1.0	1.35452
abnormality of the systemic arterial tree	GWASdb SNP-Phenotype Associations	1.0	0.112439
rab protein signal transduction	GO Biological Process Annotations 2015	1.0	null
ZNF610	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	96.4472
TAF15_02_106	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61151
H3K9me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
STAT5A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K63573625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19495
hypothyroidism	GWASdb SNP-Phenotype Associations	1.0	0.767696
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GSE123943_1_v_3_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SUZ12-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MCF7_PHA-680632_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0138963
CRCGN015_MCF10A.TP53.M_24H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.392
XPO7	Pathway Commons Protein-Protein Interactions	1.0	null
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K57242481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62718
Superior olivary complex, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00698
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Sarcoma_SARC_TCGA-DX-A2J1-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Retinal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.873
PML	ENCODE Transcription Factor Targets	1.0	null
GSE174701_1_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
RAB2A	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K58155058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3098
MOB1B	Pathway Commons Protein-Protein Interactions	1.0	null
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DD-43-WW40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227536
AR-21915096-LNCAP-1F5-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
496100431_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.78725
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0306
STX12	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K61168987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60475
GTEX-WYVS-0526-SM-3NM9W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04351
doxorubicin_homo sapiens_gpl6947_gse25741	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TBC1D7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00580185
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW1088	DepMap CRISPR Gene Dependency	1.0	2.1164
BRD-K20798215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03689
posteroventral (inferior) parietal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.41903
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.04031
SLC1A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00509352
H3K27me3_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bleomycin_mus musculus_gpl1261_gse25640	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
600MPE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.57049
BRD-K16355056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2455
GSE217541,GSE217543_0_v_1_tet1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ATR	Pathway Commons Protein-Protein Interactions	1.0	null
GSE117042_1_v_3_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NRL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5695
POLR2A_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K58670847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36841
GSE193258,GSE193259_5_v_1_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
medial superior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19265
molecular_function	GO Molecular Function Annotations 2015	1.0	null
FD-91-OK66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.755745
intermediate stratum of Pal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01777
CRCGN017_MCF10A.WT.HP_24H:K24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2094
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.02597
PL4	DepMap CRISPR Gene Dependency	1.0	3.35739
BLOC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.355
SETBP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00628491
superficial stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48395
TEAD4	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7747-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
lymphoid tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
CLTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24811
CRCGN016_MCF10A.WT.HP_24H:L11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.43378
cochlear nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.836478
Intercalated amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20245
Micronuclei, Chromosome-Defective	CTD Gene-Disease Associations	1.0	1.44954
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Amp_AA-TCGA-Unnamed_16_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.066714
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_BRD4770_1µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0134493
Prelimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67903
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.840498
BRD-K48727830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21339
SLC9A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00692422
Hepatic cecum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.485
PMC7481169-277_2020_4194_MOESM7_ESM.xlsx-RUNX1_R139G-Unnamed_1_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86771
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Foxn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.6711
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4887
BRD-K81795824_-666_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TUR	GDSC Cell Line Gene Expression Profiles	1.0	1.89227
PMC12847870-41419_2025_8402_MOESM5_ESM.xlsx-Supplemental_Table_3-Supplemental_Table_3_Top_250_genes_upregulated_in_L1236_or_L428-_conditioned_THP1-_or_monocyte-derived_macrophages_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-POYW-1326-SM-48TCG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40597
phospholipid-translocating ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.594
H3K9ac_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19012
perinuclear region of cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.519389
hsa-miR-3660	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Melanosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.394
GSE60837_0_v_4_bcl9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K51575138_TPCA-1_MDST8_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K04667232	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38635
NEK6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00516396
NBN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02787
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.437718
PMC9038526-mmc1.xlsx-postCOVID_LPS_vs_healthy_L-symbols_98_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.21813
TAF9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00515438
Early endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.858
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE218356_1_v_0_cited1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE235701,GSE261434_2_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
r3 pontine raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12962
BRD-A52627843_Thiostrepton_PC3_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08904
GSE188870,GSE188871_1_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TRIM28	ChEA Transcription Factor Targets	1.0	null
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07603
leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.051792
monocytic leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.513743
MAP4K4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00444632
SEPT8	Pathway Commons Protein-Protein Interactions	1.0	null
SHD	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-NPJ8-1826-SM-2YUNC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43491
GSE142588_2_v_1_cinobufagin_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2AphosphoS5_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RHEB	Pathway Commons Protein-Protein Interactions	1.0	null
TEX2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00726921
BRD-K87947369_VX-680_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10W-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DHRS11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00673409
NUF2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00487905
BRD-K65182930_NVP-AUY922_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC1428	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Tuberculosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.413
CSNK2A2	Pathway Commons Protein-Protein Interactions	1.0	null
BD-49-MD69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.311753
corticoid layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19117
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L8-01A-21R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of the aortic adventitia_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA1_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO201	DepMap CRISPR Gene Dependency	1.0	4.40922
BRD-K97263385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15477
GTEX-S4Z8-0226-SM-4AD5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42783
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1-23403033-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE199606_1_v_4_csf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_S-Ruxolitinib_1µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0131587
ME-31-RM40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.201092
t55-gastrocnemius_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.40853
superficial stratum of p1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00601
NKIRAS2	Pathway Commons Protein-Protein Interactions	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RM-01A-21R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FE-49-VJ28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.303511
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9198
brain	GTEx Tissue Gene Expression Profiles	-1.0	-1.19721
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.2821
A-CA-04-2009(H1N1)_0Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.87728
CEBPB_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.58587
STK38	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Leukemia_promyelocytic-HL-60	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.843232
BRD-K50841342_PAC 1_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ATP6V1A	Pathway Commons Protein-Protein Interactions	1.0	null
GPN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07985
anterior cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31206
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69682
VEGFC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0065914
Perturb_3138_KO_Med1_SRP078070	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.89975
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04863
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10R-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K23162004	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25721
SOX17	ChEA Transcription Factor Targets	1.0	null
496100582_HIP_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.89171
medial mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1131
Metabolism of proteins	Reactome Pathways 2024	1.0	null
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K47445962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28748
BRD-K16331797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06646
phagosome acidification	GO Biological Process Annotations 2023	1.0	null
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_R_species_not_found_in_common_genes_of_LF_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K50092006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01971
GSE224599_0_v_1_tfcp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
VA-48-RJ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.262957
GTEX-XOTO-2926-SM-4B65G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907661
binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00888
HT-29	GDSC Cell Line Gene Expression Profiles	1.0	1.68664
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4816-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.036372
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02804
CRCGN008_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.241
TRAT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00514755
COLO205	CCLE Cell Line Gene CNV Profiles	1.0	1.69372
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.862443
DOHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.44963
vesicle	GO Cellular Component Annotations 2015	1.0	null
GSE184902_3_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE93124_0_v_1_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Liver-monocyte	Tabula Sapiens Gene-Cell Associations	1.0	0.510662
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Oral cavity cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAPKAPK2	Pathway Commons Protein-Protein Interactions	1.0	null
17910759-TableS5	GeneSigDB Published Gene Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:F13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.05259
GTEX-Q2AI-0526-SM-2I3EJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12418
amygdaloid complex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.921772
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
SU-DHL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.839594
CEBPB-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
IL6R	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00674749
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.75002
RUNX3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00792441
RCOR1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CNOT3-19339689-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Postsubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11067
metitepine-1616	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC7346435-12864_2020_6860_MOESM6_ESM.xlsx-H1_ZF_Oocyte_Specific-GeneH_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
NPHS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00564108
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7077
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K38073091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75692
BRD-K50168500_canertinib_BT20_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7730-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K16496880	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45706
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB7A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inorganic ion homeostasis	GO Biological Process Annotations 2015	1.0	null
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85512
EGR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E20-D3_1775_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE118794_5_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
bed nucleus of stria terminalis	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.839289
GSE238116_3_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
VNN3P	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00472426
ST6GAL1_Deficiency_GDS3151_608_mouse_Mammary tumors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE158632_2_v_5_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
striatum_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	3.04064
10623_ZNF774_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.921967
GSE186810,GSE186813_3_v_5_furin_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S7SE-0011-R7A-SM-2XCDI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54911
CORL88	CCLE Cell Line Gene CNV Profiles	1.0	1.48103
Macropinosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.104
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.50134
GSE147876,GSE147877_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K28296557_Akt inhibitor IV_OV7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
17483317-TableS5	GeneSigDB Published Gene Signatures	1.0	null
esophagus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.229032
IGROV1	DepMap CRISPR Gene Dependency	1.0	2.83313
NANOG-21062744-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WL46-0011-R9A-SM-3MJFP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15679
GRIN2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00728707
GTEX-WL46-0011-R6A-SM-3LK6X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.890763
AB-33-EM56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.444666
renal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.120534
GTEX-O5YV-1126-SM-3LK73	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08507
MAP2K2	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.827485
WE-48-PP43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.322836
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE178255_1_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PVOW-0011-R5A-SM-32PL7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66817
GTEX-Q734-2026-SM-3GADA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91218
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K62533881	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16299
BMI1-19503595-MEFC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3465-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Ansiform lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49132
LGALS3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00654958
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
GTEX-WZTO-0011-R1B-SM-3NMAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21073
MCF7_PJ34_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0108792
ATF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZH-1926-SM-4DXTR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06453
Rectum adenocarcinoma_READ_TCGA-DT-5265-01A-21R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE127790_4_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210580_5_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-U88459701_atorvastatin_AGS_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
r3 part of spinal trigeminal sensory column, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36775
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.12884
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCallEPC1-PHF1_H3K27me3_k562-ENSEMBL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K24343968	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21722
EP300_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNAP29	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K29707171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21019
HSD3B7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00609541
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE157594_3_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K79me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
ELMO3	Pathway Commons Protein-Protein Interactions	1.0	null
icSARS CoV_3Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-0.509525
SW1271	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73084
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.7673
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A8RZ-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Apical plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.049
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.97139
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA46	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.3541
SOCS3_DELETION_GDS1254_80_mouse_ES (embryonic stems cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.36721
GTEX-XQ3S-1726-SM-4BOOD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25814
GATA3_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE220520_3_v_4_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.255306
GSE111035,GSE111040_8_v_5_plag1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K83213280_-666_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
amygdaloid complex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00299
GSE213228_2_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20539
GSE217115_3_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Dasatinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00931452
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S32W-1926-SM-4AD63	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904538
RAD21_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP1	ENCODE Transcription Factor Targets	1.0	null
PMC11659402-41523_2024_709_MOESM3_ESM.xlsx-Sheet2-ESR1_mutation_E2_Co-Down_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K56341841	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17803
TAF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Spleen-classical monocyte	Tabula Sapiens Gene-Cell Associations	1.0	2.2987
CD207	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00594291
GPR132	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00512413
GTEX-QMR6-0011-R4A-SM-32PKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.899784
2112_DDX23_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.524
HDH_CAG knock-in_GDS3935_569_mouse_Striatum and cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ERGIC2	Pathway Commons Protein-Protein Interactions	1.0	null
Recycling endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.53
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07037
GSE178714_5_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QXCU-0006-SM-2TC5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16529
regulation of intracellular ph	GO Biological Process Annotations 2015	1.0	null
GSE213228_4_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_downregulated-Ensembl_ID_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51503
BRD-K48113764	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30375
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.5979
KPNB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00888865
BRD-K14570970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1983
NUCB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12134
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE161064,GSE161065_0_v_1_kdm5b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.86451
GTEX-N7MS-0011-R4a-SM-2HMKW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.959679
BIK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00521783
GATA2-19941826-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_SUZ12_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-O2-A52Q-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A898-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE102132_2_v_1_irf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
TEAD4_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Intestinal benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.179
H3K4me1_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BHLHE40_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K28874552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94977
Legionnaires' disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.099
NEK9	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K79753227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42654
GSE124410_6_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
early phagosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.926543
GSE185519_4_v_7_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.168598
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of m1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29494
hsa-miR-3678-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_PRDM14_21183938	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_RNF2_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
rab20	GeneRIF Biological Term Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7072-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSEN1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE239541_8_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38169
MAPK13	Pathway Commons Protein-Protein Interactions	1.0	null
DYRK1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00591839
GSE217115_2_v_0_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00143
myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.102344
isoxicam-7268	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_1016_KO_Nt5e_SRP404924	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.1042
NDEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22355
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051977
BRD-K55662526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17093
PPM1B	Pathway Commons Protein-Protein Interactions	1.0	null
GSE228181_0_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-1260b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GTEX-P4QS-0926-SM-48TBS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47135
BRD-U61997977_WZ-4-145_A549_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Intracellular vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
HAUS1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE146074_0_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.972212
Prostate adenocarcinoma_PRAD_TCGA-J4-A67R-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELK4	ENCODE Transcription Factor Targets	1.0	null
RARA-24833708-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE193258,GSE193259_5_v_15_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K32702774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71744
ERGIC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00731215
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IN-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMC3	Pathway Commons Protein-Protein Interactions	1.0	null
female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43S-01A-21R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PDE4C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00843677
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_288_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P44H-0011-R11A-SM-2XCER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57358
Cell type benign neoplasm	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.946
GTEX-NPJ7-0011-R11A-SM-2I3E8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28516
MZ in posterodorsal (superior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.83795
GSE175787_13_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
PIK3R4	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_11864_KO|KD|OE_Trp53/Rb1|Kmt2c|Myc_SRP292755	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13088
GSE132759_4_v_2_fgfr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CACNB3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00631143
EPAS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9844
FAM131B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18074
BRD-K14027855_-666_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1ME-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VP-A872-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VPS25	Pathway Commons Protein-Protein Interactions	1.0	null
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE230744,GSE237803_5_v_2_hira_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
A172	DepMap CRISPR Gene Dependency	1.0	3.28483
KLF4-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
stratum radiatum of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.46094
DOCK1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE169617_1_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Hypertrophy	CTD Gene-Disease Associations	1.0	1.12872
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063952
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AY-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
duodenum	HPA Tissue Protein Expression Profiles	1.0	1.8234
Gastric	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.977267
H3K9ac_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K31806725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33397
WC-33-YP46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.206551
9738_VPS13A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.511021
GTEX-X4EP-0826-SM-3P5YK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07761
CRCGN011_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3251
GTEX-SIU8-0526-SM-2XCDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.983038
BRD-K52620056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50826
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEF2D_KD_GDS4759_339_mouse_E16 primary cortical neuron cultures	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.608
DOCK4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00928969
Perturb_12030_KD_ADORA1_SRP215261	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
KLRK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00600746
STX3	Pathway Commons Protein-Protein Interactions	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K09977699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07851
early endosome	GO Cellular Component Annotations 2025	1.0	null
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.51532
CEBPB-20513432-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
KLF15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	114.284
GSE124410_2_v_5_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Posterolateral visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55653
SUIT-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.928358
SPC25	Pathway Commons Protein-Protein Interactions	1.0	null
HD-51-KD29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.294502
ATP5F1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0039255
HTR3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00443652
CRCGN015_MCF10A.TP53.M_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.93675
NB-80-IM48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.980357
Lung squamous cell carcinoma_LUSC_TCGA-77-8007-11A-01R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85176
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5881-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MTA3	ENCODE Transcription Factor Targets	1.0	null
GSE125403_7_v_6_venetoclax_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZEB1	ENCODE Transcription Factor Targets	1.0	null
CEBPB_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE174701_5_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
purine ribonucleoside triphosphate binding	GO Molecular Function Annotations 2015	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MF-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2-18974828-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CA4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00734861
superior parietal lobule, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.24039
EZH2-18974828-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
EGR4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.5491
KAT2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JU-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE213228_1_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
ARCN1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K89744662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.56608
GFI1_KO_GDS4204_147_mouse_HSC	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Legionellosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.073
BRD-K91588908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7295
Simple lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03112
PMC8755441-mmc3.xlsx-ISGsets-IFNs-averageFC-ISGF3-ZP_IRF9	Rummagene Transcription Factor Associations 2026	1.0	null
GSE148066,GSE157787_3_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE122215,GSE122217_0_v_4_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mediodorsal nucleus of thalamus_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.47382
BRD-K83213911_PF 750_HA1E_24.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SPI1-23547873-NB4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC7161353-supp_073353.119_Supplemental_Tab_S8.xlsx-BRCA_HRGs_correlation_to_MBNL2-gene_name_MBNL2	Rummagene Transcription Factor Associations 2026	1.0	null
CL40	CCLE Cell Line Gene Expression Profiles	1.0	1.40665
SU-DHL-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.5344
MAPK14	Pathway Commons Protein-Protein Interactions	1.0	null
COLO-678	GDSC Cell Line Gene Expression Profiles	1.0	1.55328
EEF1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-7.82121
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PD-70-VS77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.240166
medial tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18624
GTEX-QDT8-0011-R11A-SM-32PKD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.27824
GSE167373_0_v_3_rbfox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE185519_3_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-875-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0051
GTEX-RUSQ-0426-SM-47JWR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11429
PTPN6	Pathway Commons Protein-Protein Interactions	1.0	null
ELK1	ENCODE Transcription Factor Targets	1.0	null
GPR25	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00519397
hsa-miR-4734	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GSE129241_3_v_6_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6001
SPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93099
DYNC1LI1	Pathway Commons Protein-Protein Interactions	1.0	null
PICK1	Pathway Commons Protein-Protein Interactions	1.0	null
PAX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14305
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.79026
SMC1A	Pathway Commons Protein-Protein Interactions	1.0	null
striatum_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.67045
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
GSE148692,GSE148695_2_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
testis	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
SCN1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00676967
COLO205	BioGPS Cell Line Gene Expression Profiles	1.0	1.80404
17660535-TableS4c	GeneSigDB Published Gene Signatures	1.0	null
STAT4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00533485
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.911645
BRD-A81530502_8009-7630_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.83116
Macropinocytic cup	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.729
GSK3B_knockdown_202_GDS4305	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.4438
LOXL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00390078
BRD-K28296557_Akt inhibitor IV_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
BRD-A19500257_geldanamycin_HT29_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PIAS1-25552417-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Neurosphere_Cultured_Cells_Ganglionic_Eminence_Derived	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.934431
BRD-A56592690_PX12_NCIH1694_6.0_h_30.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN015_MCF10A.TP53.M_24H:I05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5698
GTEX-P44H-2426-SM-2XCEJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12004
Phagocytic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
H3K27me3_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BE-27-RQ61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.206154
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Fasudil_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0146974
BRD-K58827489	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13871
GTEX-X261-0011-R11A-SM-4E3JY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44674
RPS6KA4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00645616
GSE200430_1_v_0_sema3d_human	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of the cerebrum	GWASdb SNP-Phenotype Associations	1.0	0.232717
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.71162
FOXA2	ENCODE Transcription Factor Targets	1.0	null
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cervical carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.097909
biological_process	GO Biological Process Annotations 2015	1.0	null
GTEX-OHPN-0226-SM-48TBV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08202
PHC1-16625203-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-A46778020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87333
CRCGN017_MCF10A.WT.HP_24H:N18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.66295
cytoplasmic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.168349
BRD-K28907958_-666_U937_6.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE135514_2_v_6_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Neutropenia	CTD Gene-Disease Associations	1.0	1.12703
7525_RPS3_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.591599
GTEX-PWCY-0226-SM-48TD8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856347
ARHGEF26	Pathway Commons Protein-Protein Interactions	1.0	null
PSMD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00804983
superficial stratum of isLim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14669
GSE196318_0_v_1_xpo4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WL46-0011-R5A-SM-3LK6V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03904
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4834-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.865049
HLA-B	Pathway Commons Protein-Protein Interactions	1.0	null
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.48663
BRD-K27221973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60368
Perturb_99_KD_Dis3l2_SRP318863	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
SPTBN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00612192
KM-12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
CD40LG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00527645
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.855851
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE225982_2_v_0_ezetimibe_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.70124
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52813
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08878
GBF1	Pathway Commons Protein-Protein Interactions	1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29V-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX2	ChEA Transcription Factor Targets	1.0	null
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WWYW-0426-SM-3NB31	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34813
RANBP1	Pathway Commons Protein-Protein Interactions	1.0	null
KIF11	Pathway Commons Protein-Protein Interactions	1.0	null
C1S	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0063562
GSE125014_6_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE148262,GSE150691_1_v_0_hdlbp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K36me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.32184
GATA2-21666600-HMVEC-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RPS6KA5	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN015_MCF10A.TP53.M_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1793
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EN-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FA-80-DR66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203199
GSE242049_1_v_0_txndc5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
CEBPB_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Accelerated cognitive decline after conversion of mild cognitive impairment to Alzheimer's disease (Alzhiemer's diagnosis trajectory interaction)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K87909389_alvocidib_MDAMB231_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01591
RUNX2	ChEA Transcription Factor Targets	1.0	null
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostatic Diseases	CTD Gene-Disease Associations	1.0	1.18882
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DCTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47539
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Apical recycling endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.422
LOVO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC5637904-PATH-243-193-s016.xlsx-human_down_in_fat_SOX11-Unnamed_6_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
SPTLC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00470521
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.25877
PMC7902901-Table_12.xlsx-STAT1-Unnamed_7_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
Main olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18758
organelle membrane fusion	GO Biological Process Annotations 2015	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2813-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ruffle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.382
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SYK_knockdown_189_GSE54065	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.28678
hsa-miR-103b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Perturb_10616_KO_Ttn_SRP136441	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.246
CA-68-KG29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.343059
outer plexiform zone in extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.63911
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.43146
USP9X	Pathway Commons Protein-Protein Interactions	1.0	null
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE194396,GSE194429_1_v_0_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.83311
Bone Marrow Diseases	CTD Gene-Disease Associations	1.0	1.02896
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12881
clidinium	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18009
intracellular signal transduction	GO Biological Process Annotations 2015	1.0	null
MAFF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARL5A	Pathway Commons Protein-Protein Interactions	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.57774
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HG3	DepMap CRISPR Gene Dependency	1.0	2.76052
mantle zone of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08465
COLO 205	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.50185
GSE242555_1_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Small GTP-binding protein domain	InterPro Predicted Protein Domain Annotations	1.0	null
BRD-K69097969_VU0418939-2_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTNNB1	ChEA Transcription Factor Targets	1.0	null
GSE242199_2_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CD-05-PU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.66477
GTEX-POYW-0006-SM-2XCF4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06096
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6I0-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF1	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6K1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.48163
MXI1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
HCFC1	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-TKQ2-0826-SM-33HB6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.844721
GSE199543,GSE239447_0_v_4_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH2009	CCLE Cell Line Gene CNV Profiles	1.0	1.53461
ITGB5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00418696
PPARG-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K97763545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81333
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXA2_FOXA2	Rummagene Transcription Factor Associations 2026	1.0	null
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.13464
BRD-K32686643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.1004
GSE149264,GSE149267_2_v_1_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Adrenalgland	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55354
TAF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSK3B	Pathway Commons Protein-Protein Interactions	1.0	null
GSE133516_5_v_2_kat7_human	RummaGEO Gene Perturbation Signatures	1.0	null
Hemolysis	CTD Gene-Disease Associations	1.0	1.12495
RNF2-16625203-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K73395020_ARP 101_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FOXA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.848089
Lateral visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34135
BRD-K79090631_CGP-60474_BT20_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K19310540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09852
Peripheral_Blood_Mononuclear_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.910178
GTEX-Q2AG-0011-R5A-SM-2HMJH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858473
SW620	CCLE Cell Line Gene Expression Profiles	1.0	1.4234
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.216
GSE158632_2_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72823
BRD-K27228812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65911
BRD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00636845
GSE220287_2_v_1_mef2d_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K91784140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18922
GTEX-T6MN-2526-SM-32PMN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00428
NEU1	Pathway Commons Protein-Protein Interactions	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE223008_0_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VAPB	Pathway Commons Protein-Protein Interactions	1.0	null
doxorubicin-4610	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RNF2-18974828-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PLEKHA1	Pathway Commons Protein-Protein Interactions	1.0	null
NANOG_01_94	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-1.56007
BRD-K25444802	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05296
BD-49-MD69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.613012
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A6E9-06A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GABPA	ENCODE Transcription Factor Targets	1.0	null
LYAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17819
FOXP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00703963
MT-CYB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38046
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48287
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_5053_KO_Ring1/Rnf2_SRP078684	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.86936
plasma membrane region	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.100786
karpas707	HPA Cell Line Gene Expression Profiles	-1.0	-2.39936
CNOT3-19339689-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-POMQ-1926-SM-3NB1Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876815
CRCGN008_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6529
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42154
GSE201309_1_v_6_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
NSF	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K53559383	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15019
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U6-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
STL336112	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.56
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.997034
BRD-K96054771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.04366
CTSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03232
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.836506
RBM15_02_171	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59535
MYO1E	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0073831
GSE213588_8_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BHLHE40	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00363105
BRD-K80724940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19459
GSE135514_2_v_9_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RNF2-16625203-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.328
U87MG_CENTRAL_NERVOUS_SYSTEM	CCLE Cell Line Proteomics	1.0	2.33649
Perturb_4594_KO_Bcl9l/Bcl9_SRP045828	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.2755
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
QB-88-PG52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.233627
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC3435504-msb201237-s2.xls-Supp_Table_4a-MYBL2_MYBL2	Rummagene Transcription Factor Associations 2026	1.0	null
cytoplasmic membrane-bounded vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K27me3_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IL-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE213588_8_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12047497-mmc5.xlsx-Sheet1-GSE20754_WT_VS_TCF1_KO_MEMORY_CD8_TCELL_UP_HNF1A	Rummagene Transcription Factor Associations 2026	1.0	null
20174566-TableS1	GeneSigDB Published Gene Signatures	1.0	null
chr13_110551134_A_G_b38	GTEx eQTL 2025	1.0	3.03795
GTEX-NL3H-0011-R3a-SM-2I3GL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26375
NXPH4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00648073
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K13859368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29395
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0011-R10A-SM-2HMJK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14628
supramarginal gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.882794
GTEX-UJMC-0726-SM-3GADX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926237
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.50995
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.3549
adrenal_4c	HPA Tissue Sample Gene Expression Profiles	1.0	0.836094
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
PRKAB1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K41513047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6884
PMC7902901-Table_12.xlsx-JUN-Unnamed_7_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
RAB3A_KO_GDS2482_706_mouse_Hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SW948	CCLE Cell Line Gene CNV Profiles	1.0	1.71444
SMARCA4	ChEA Transcription Factor Targets	1.0	null
Perturb_7058_KO_Sod2/Ogg1_ERP107154	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.8479
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01549	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.25964
GTEX-WZTO-0011-R11A-SM-4E3K9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60458
BRD-K47599661	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01924
Perturb_805_KO_Trim28_ERP125317	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.38441
SB-228357	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03395
SCAMP3	Pathway Commons Protein-Protein Interactions	1.0	null
lymphatic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.651298
H4K5ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ESR1	JASPAR Predicted Transcription Factor Targets	1.0	null
PMC9911396-41467_2023_36178_MOESM11_ESM.xlsx-Sheet1-Genes_in_10kb_vicinity_of_ZBTB12_ChIP-seq_peaks_ZBTB12	Rummagene Transcription Factor Associations 2026	1.0	null
PHOX2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13877
KIR3DL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00509651
Skin Cutaneous Melanoma_SKCM_TCGA-HR-A2OH-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE127790_5_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4580625-pone.0138726.s006.xlsx-Immune_molecular_modules-ETS2_mod_ETS2	Rummagene Transcription Factor Associations 2026	1.0	null
6-10B cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.667
GSE124097_3_v_0_trem2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GNAZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15779
membrane fusion	GO Biological Process Annotations 2015	1.0	null
H-EMC-SS	GDSC Cell Line Gene Expression Profiles	-1.0	-2.00343
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21243
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAPK3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K93310782	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42962
GSE76425_0_v_7_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K11663430_-666_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A6I3-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BL-70 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.92
GSE223008_9_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XXEK-0626-SM-4BRWE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857473
BRD-K62318087	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41575
CRCGN009_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.07149
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLA2G4A	Pathway Commons Protein-Protein Interactions	1.0	null
TFAP2C	ChEA Transcription Factor Targets	1.0	null
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RELA	ENCODE Transcription Factor Targets	1.0	null
SOX2-27498859-CHIP-SEQ-STOMACH-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Mobilized_CD34_Primary_Cells_Female	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.21136
pindolol-2075	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ATRIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09648
GSE152666,GSE152668_2_v_1_carm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hypertension	CTD Gene-Disease Associations	1.0	1.23456
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Platelet dense granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.666
periventricular stratum of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03471
AP3S1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K70819166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.1078
NCI-H630	GDSC Cell Line Gene Expression Profiles	1.0	1.49041
abnormality of the vasculature	GWASdb SNP-Phenotype Associations	1.0	0.079775
SMPD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00610853
GSE235066_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.073064
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.89222
RIN1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-downregulated_in_ATF4OE-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05708
CRCGN017_MCF10A.TP53.M_24H:P21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26881
BRD-K99250186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.68942
GSE148066,GSE157787_2_v_1_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.31148
Drug-Related Side Effects and Adverse Reactions	CTD Gene-Disease Associations	1.0	1.09154
JHH-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13613
PMC12518476-10067_2025_7574_MOESM8_ESM.xlsx-Sheet1-Up_regulated_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
phagocytic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
SPI1_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K64606589_-666_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MAD2L1	Pathway Commons Protein-Protein Interactions	1.0	null
striatal part of olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20539
NFKB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.1864
early endosome	GO Cellular Component Annotations 2015	1.0	null
3-Deazaneplanocin A	DeepCoverMOA Drug Mechanisms of Action	1.0	0.74
r7 portion of ambiguous motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13018
GSE211989_0_v_1_nlrc3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GATA3_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CUX1	Pathway Commons Protein-Protein Interactions	1.0	null
TCF3	ENCODE Transcription Factor Targets	1.0	null
intracellular pH reduction	GO Biological Process Annotations 2025	1.0	null
hypothyroidism	GWASdb SNP-Disease Associations	1.0	0.874542
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K76907295_VU0418947-2_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ADGRL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27348
ERGIC1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-UTHO-0011-R4A-SM-3GIJP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.871043
M040416	DepMap CRISPR Gene Dependency	1.0	2.16593
GTEX-WL46-2826-SM-3LK81	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.8785
CRCGN008_HEPG2_24H:M12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21905
2300_DNAJC4_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.544831
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.844925
DYNLRB1	Pathway Commons Protein-Protein Interactions	1.0	null
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.312
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K52001024	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26643
GUK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41643
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC12703482-AMS-21-5-213605-s2.xlsx-Supplementary_Table_SXIII-SMR_results_of_expression_levels_of_VDR_target_genes_in_peripheral_blood_and_risk_of_breast_cancer_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
Active Tuberculosis	DisGeNET Gene-Disease Associations	1.0	null
GSE163240_3_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE151612_4_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
H2AC12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00442915
lateral superior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04104
H3K4me3_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060835
GSE127790_11_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ChIP_EED_16625203	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PMC7902901-Table_12.xlsx-MITF-Unnamed_7_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
ciclopirox-6677	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.178403
MS4A4A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00692102
BRD-K60886324	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53278
BAG2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00542326
ZFP281-18757296-E14-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PSG3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00661239
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
PDZD8	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-4751	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GSE214382,GSE214383_5_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S341-1826-SM-3K2AB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.959654
ECC12	CCLE Cell Line Gene Expression Profiles	-1.0	-2.30422
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
IL11RA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52129
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
kanamycin-1609	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2AphosphoS5_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer 2 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.92918
protein transport	GO Biological Process Annotations 2015	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.913634
PMC12685885-Table1.xlsx-Table_S9-Du_PanCancer_ATF3_SMC_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
FOXA1	ENCODE Transcription Factor Targets	1.0	null
RPMI8226_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	2.43413
GSE202933_1_v_0_ugt2b28_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12528040-Data_Sheet_1.pdf-15-KLF4_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
NF2	Pathway Commons Protein-Protein Interactions	1.0	null
STARD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00558895
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.1399
Lymph_Node-classical monocyte	Tabula Sapiens Gene-Cell Associations	1.0	-0.0482817
NRK cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.501
SK-N-FI	GDSC Cell Line Gene Expression Profiles	-1.0	-1.59461
GSE262134_0_v_1_dnajc12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NPJ8-1626-SM-2HMIY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35553
ZB-16-BR73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.705445
PMC6995218-12864_2020_6525_MOESM3_ESM.xlsx-D2FAST48h_vs_D3REFED24h_1198_AR-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
RBX1	Pathway Commons Protein-Protein Interactions	1.0	null
TYKNU	DepMap CRISPR Gene Dependency	1.0	2.09603
BRD-K80763723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15478
GTEX-X4XX-0011-R3B-SM-46MWK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856399
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19758
GTPBP1	Pathway Commons Protein-Protein Interactions	1.0	null
MRTO4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00742618
hsa-miR-4257	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
ELK1-19687146-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
EED-16625203-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K82325043	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1108
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.965037
ZBTB7B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2674
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
UNC93B1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K33102216	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53062
Crus 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52563
nucleoside-triphosphatase activity	GO Molecular Function Annotations 2015	1.0	null
GSE235066_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-4784	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
PMC6225799-annrheumdis-2018-213524supp003.xlsx-Activated-state-LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE205163,GSE205164_3_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ARL15	Pathway Commons Protein-Protein Interactions	1.0	null
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE108326_1_v_0_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MBTPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17863
GTEX-OIZH-0126-SM-2HMIS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845326
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE197555_0_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
XRCC5_02_114	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60998
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
HGS	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBC1D10B	Pathway Commons Protein-Protein Interactions	1.0	null
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18299
KLC4	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72507
BRD-K67586245	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88592
Malignant exocrine pancreas neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.427
WDFY1	Pathway Commons Protein-Protein Interactions	1.0	null
Cyanuric chloride	DeepCoverMOA Drug Mechanisms of Action	1.0	0.33
Cortical amygdalar area, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28803
3535_GRHPR_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.682564
GSE118794_2_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.5918
ELK1-19687146-Hela cells-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.365
KLC2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OHPK-1826-SM-2YUMR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834681
GSE206516,GSE206518_2_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.860953
Brain Lower Grade Glioma_LGG_TCGA-HT-7684-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mitomycin	CTD Gene-Chemical Interactions	1.0	null
mantle zone of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0091
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02206
GSE186810,GSE186813_3_v_5_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Nausea	CTD Gene-Disease Associations	1.0	1.1294
Perturb_352_OE_JUNB_SRP287831	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Thyroid gland disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.983
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.374
JUN-21703547-K562-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
7877_SH3BP1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.569862
GTEX-U4B1-0526-SM-4DXTK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19518
CRCGN015_MCF10A_48H:L07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.18446
benzydamine-1552	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
STAT4-19710469-TH1 cell mouse-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
REST_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KCNJ4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0050543
Postpiriform transition area, layers 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18672
GSE184087_2_v_1_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE196117_1_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
endocytic vesicle	GO Cellular Component Annotations 2023	1.0	null
Perturb_3121_KO_Slc45a3_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.54674
CEBPB_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE102675_3_v_0_atf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCILY3	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63656
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
lateral subdivision of BNST	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.972503
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.64919
BRD-K10900122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35101
SLC16A14	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00498383
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61O-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01304
Pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.357
abnormal macrophage physiology	MGI Mouse Phenotype Associations 2023	1.0	null
Bed nuclei of the stria terminalis, anterior division, rhomboid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45081
GTEX-REY6-1726-SM-48FDL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21631
VPS16	Pathway Commons Protein-Protein Interactions	1.0	null
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.95619
AF-99-HA02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.493364
ZFPL1	Pathway Commons Protein-Protein Interactions	1.0	null
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPP2R2D	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.009533
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18658
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04036
r1 part of intermediate nucleus of the lateral lemniscus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.59866
GSE133505_5_v_4_myf6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KLF10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00381603
XPOT	Pathway Commons Protein-Protein Interactions	1.0	null
NELFE	ENCODE Transcription Factor Targets	1.0	null
BHLHE40_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K21253219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37673
BC-40-TU13_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200144
PSG4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00671156
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29176
GSE242049_1_v_0_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
adult stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.09875
BRD-K54236126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44267
paracentral lobule, anterior part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04232
BRD-K88278225_-666_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SUM159PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.758168
GTEX-WZTO-0011-R5B-SM-3NMC5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900071
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMAD3	ChEA Transcription Factor Targets	1.0	null
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051279
SW 480	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.39675
Bladder	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.16998
GSE223008_5_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SUZ12-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ATF1	ENCODE Transcription Factor Targets	1.0	null
Gustatory areas, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68344
GSE207514,GSE207515_0_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
rnf2_20123906_mouse_embryonic_stem_cell_lof_mouse_gpl1261_gse19076	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.053677
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MYBL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29383
GSE201657_0_v_1_ash2l_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HDAC6_KO_GDS4375_372_mouse_CD4+CD25+ T-regulatory cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K99749624_linifanib_HA1E_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SEC61B	Pathway Commons Protein-Protein Interactions	1.0	null
HM13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00521529
Phagocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.232
aplastic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.352659
PTPN4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00594223
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06733
intermediate isthmic part of the dorsal raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00201
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE223008_9_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TBC1D9B	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K45909830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47438
GSE48812_0_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Contractile vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.712
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CLEC4A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00630052
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876231
HASPIN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00766635
NCI-H522 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.566
RAMP3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00557715
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.856303
GATA3-21867929-CD8-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73253
GTEX-TSE9-0011-R11A-SM-3DB7N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.931608
RI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.839594
Perturb_9775_KD_FYB1_SRP361457	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.45335
GSE98964_0_v_2_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
UBTF	ENCODE Transcription Factor Targets	1.0	null
PATU8988T_PANCREAS	CCLE Cell Line Proteomics	1.0	2.57955
PMC11699082-BLOODA_ADV-2023-012291-mmc1.xlsx-Sheet1-CD37_inv_corr_top100_GSE10846_CHOP_GCB_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A5KD-11A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAL1-30185409-K562-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
STX17	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K51313569_palbociclib_HT29_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GOLT1B	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K47200630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02012
GSE182181_1_v_0_ricolinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BL-60 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.218
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
reduced	GeneRIF Biological Term Annotations	1.0	null
Benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.168
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE166169_1_v_3_elp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U8XE-1226-SM-4E3HN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925369
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF148	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	161.445
hsa-miR-568	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
BRD-K34318928	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.30851
mantle zone of LPrP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37522
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A6NJ-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_SYMBOL_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WVLH-0011-R4A-SM-3MJFS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827532
LILRP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00711818
RABEPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57957
ABCA6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00657839
DB-54-GQ68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.362653
phagocytic vesicle	GO Cellular Component Annotations 2025	1.0	null
protein localization	GO Biological Process Annotations 2025	1.0	null
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
isoproterenol hydrochloride_rattus norvegicus_gpl1355_gse7999	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
golgi apparatus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE135439_0_v_1_pax5_human	RummaGEO Gene Perturbation Signatures	1.0	null
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.057474
GTEX-QMR6-0011-R11A-SM-32PKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.02964
BRD-K28360340_TW 37_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE214514_3_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IE-49-AI35_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.232001
H3K4me1_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K87640319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72471
Phagocytic cup	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.193
LANCL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00677983
GTEX-T8EM-0526-SM-4DM64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01047
GSE152441,GSE152442_1_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Small GTPase superfamily	InterPro Predicted Protein Domain Annotations	1.0	null
USO1	Pathway Commons Protein-Protein Interactions	1.0	null
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1025
GSE218098,GSE218099_1_v_0_tcf19_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135350_3_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.935844
GTEX-RU72-1326-SM-2TF6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901338
GCDH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00655688
GTEX-WVLH-3026-SM-3MJG9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49571
TRIM28-19339689-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC7161353-supp_073353.119_Supplemental_Tab_S8.xlsx-LUAD_HRGs_correlation_to_MBNL2-gene_name_MBNL2	Rummagene Transcription Factor Associations 2026	1.0	null
IZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.893156
blast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.119669
abnormality of brain morphology	GWASdb SNP-Phenotype Associations	1.0	0.119147
KMT2E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03437
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
cellular cation homeostasis	GO Biological Process Annotations 2015	1.0	null
Fetal_Brain_Female	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.03891
Muscle-macrophage	Tabula Sapiens Gene-Cell Associations	1.0	1.34761
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31632
PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-DMOG_-_HIF1A-gene_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
NF1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K22475995	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28899
hippocampus (hippocampal formation)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.979171
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K31683335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00993
SUZ12-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01315
H3K27me3_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
biological regulation	GO Biological Process Annotations 2015	1.0	null
CD47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32753
GSE196117_1_v_11_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BLOC-2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.905
COPE	Pathway Commons Protein-Protein Interactions	1.0	null
PMC7067536__F7	PFOCR Pathway Figure Associations 2023	1.0	null
TUBB2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00493727
FOXA1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletal muscle	HPA Tissue Protein Expression Profiles	1.0	0.78613
STAM	Pathway Commons Protein-Protein Interactions	1.0	null
STAT6	Pathway Commons Protein-Protein Interactions	1.0	null
RAB geranylgeranylation	Reactome Pathways 2024	1.0	null
Macrophage cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.418
BRD-K54081441	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15195
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
17616640-TableS3	GeneSigDB Published Gene Signatures	1.0	null
ALDH5A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0065916
BRD-K80439500	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54926
DNM1L	Pathway Commons Protein-Protein Interactions	1.0	null
CUX1	ENCODE Transcription Factor Targets	1.0	null
BRD-K24132293_piperlongumine (HPLC)_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ERF::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.0017
cellular ion homeostasis	GO Biological Process Annotations 2015	1.0	null
GTEX-S33H-0826-SM-4AD5Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2514
AFF3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00455812
Urogenital Abnormalities	CTD Gene-Disease Associations	1.0	1.13449
H3K4me1_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Endocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.193
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A61304759_tanespimycin_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00609
intermediate stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28494
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PPP3R2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00507511
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.012
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE114992,GSE114993_7_v_11_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Secondary motor area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.14079
GSE96641_1_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE126219_0_v_1_haloperidol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC5303304-13073_2017_407_MOESM3_ESM.xlsx-mycn-sy5y-se_single_24DMSO_vs_2-Table_S2_Genes_differentially_expressed_by_24h_RA_treatment_DE_comparison_with_SY5Y-MYCN_control_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.910736
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JC-06-ED36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.243239
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.872674
CTNNB1-20460455-HCT116-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WFON-0126-SM-4LVM9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93352
HUPT4	DepMap CRISPR Gene Dependency	1.0	4.09488
Congenital Abnormalities	CTD Gene-Disease Associations	1.0	1.22727
hsa-miR-128	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
SNX3	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-QH-A6CW-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	108.513
PMC7417338-Table_1.xlsx-Sheet1-AHR_1_AHR	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN010_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.21897
PMC10870497-13046_2024_2976_MOESM12_ESM.pdf-17-HOXC6_HOXC6	Rummagene Transcription Factor Associations 2026	1.0	null
cervical cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.103328
IA-76-ZU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.356009
membrane-bounded vesicle	GO Cellular Component Annotations 2015	1.0	null
HDQP1	CCLE Cell Line Gene CNV Profiles	1.0	1.50156
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EPHB2	Pathway Commons Protein-Protein Interactions	1.0	null
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.900877
u266	HPA Cell Line Gene Expression Profiles	-1.0	-0.889523
HT55	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.00817
hydrolase activity	GO Molecular Function Annotations 2015	1.0	null
SLC2A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00523074
BRD-K51843685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07431
GSE159678_6_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UC-58-DM11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.270736
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE213588_10_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE138841_0_v_1_trim6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6326-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34389
TFDP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0060672
GSE196962_2_v_6_parg_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OXCT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33126
PTK2B	Pathway Commons Protein-Protein Interactions	1.0	null
SNTB2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE122215,GSE122217_0_v_1_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
rostral subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29387
1318_CCNB2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.568729
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.93009
NANOG-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE133691_2_v_0_lgr5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_6956_KO_Tefm_SRP114827	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.9445
RAB5A	Pathway Commons Protein-Protein Interactions	1.0	null
ODAD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52924
YD-49-HM53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.657851
Perturb_797_KO_Tnfaip3_SRP332632	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Mueller cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.219
SP in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.44731
hsa-miR-340	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GTEX-OIZG-0005-SM-2HMJC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52807
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HL-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUN	ChEA Transcription Factor Targets	1.0	null
KYSE520	CCLE Cell Line Gene CNV Profiles	1.0	1.88724
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A37704979_SB-203580_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
phagocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.662503
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC7439574-13148_2020_914_MOESM2_ESM.xlsx-log2_fold_change_2-1769_genes_are_more_than_four-fold_upregulated_in_PRDM8-_-_compared_to_control_PRDM8	Rummagene Transcription Factor Associations 2026	1.0	null
SmoothMuscle	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.981235
primary auditory cortex (core)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14315
CENPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.542
GTEX-QEG5-0626-SM-2S1PP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02256
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056739
KLF4	ChEA Transcription Factor Targets	1.0	null
layer 6 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30829
BRD-K25504083_C8273_ASC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
STK39	Pathway Commons Protein-Protein Interactions	1.0	null
GSE225901_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K03339354	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16093
496100608_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.00692
BRD-K56343971_vemurafenib_MDAMB231_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11034
cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00965
SFT2D2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE210662_2_v_0_znf165_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.286
GSE118794_0_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9170821-JCMM-26-3183-s001.xlsx-Mic_DAPI_ERG_VaDadj_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
SJSA-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
SP5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.6467
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.35736
PPP2R2A	Pathway Commons Protein-Protein Interactions	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.55226
NANOG-16518401-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
COLO 206F	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.84898
BRD-K28093873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55489
Hermansky-Pudlak syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.218
inner CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32108
nucleoside binding	GO Molecular Function Annotations 2015	1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A3LU-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04242
GATA2-19941826-K562-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3646	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
BRD-K44139682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06045
VPS37B	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_9759_KO_CTCF_SRP102228	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	16.8324
BRD-K50931403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.78031
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.163
BRD-K13566078_BMS-345541_MDAMB231_3_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE101239_4_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.27963
H3K4me1_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.975255
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K19220233_JNK-9L_HME1_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT4	ChEA Transcription Factor Targets	1.0	null
ARNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07827
MXI1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary hematopoietic stem cells G-CSF-mobilized Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.01611
GSK3B_knockdown_208_GDS4305	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.61553
H3K36me3_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052758
GSE111102,GSE111105_1_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ARF6	Pathway Commons Protein-Protein Interactions	1.0	null
DOV13	DepMap CRISPR Gene Dependency	1.0	4.24604
homeostatic process	GO Biological Process Annotations 2015	1.0	null
Agranular insular area, ventral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50502
GTEX-UTHO-0726-SM-3GAEN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.964238
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3428-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K10882151_BO2 (inhibits RAD51)_A673_6.0_h_40.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BAIAP2	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11046918-12967_2024_5211_MOESM4_ESM.xlsx-F_HT1080_FUS-DDIT3_regulated-Table_S2_Regulated_genes_between_scaffold-cultured_and_monolayer-cultured_cells_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WI4N-1426-SM-3LK7H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838347
USE1	Pathway Commons Protein-Protein Interactions	1.0	null
purine ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QLQW-0126-SM-447BK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.999453
NANOG-16518401-CHIP-PET-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
RELA_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DB-21-FY75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.40962
GSE152055_2_v_3_mpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01379
GSE174406_2_v_1_lin28b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TM9SF1	Pathway Commons Protein-Protein Interactions	1.0	null
K562	Achilles Cell Line Gene Essentiality Profiles	1.0	1.11469
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
JB-75-NC66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.306504
H3K4me1_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TAP2	Pathway Commons Protein-Protein Interactions	1.0	null
EP300_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ESCRT IV complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.719
RIC8A	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OOBK-0526-SM-2HMJJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05914
18801183-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-NPJ8-1926-SM-3MJGB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11351
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.117
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K08109215_I-BET_HCC515_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EXOC3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE160246_0_v_1_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE247764_3_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE114883_1_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
KDM5C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00495051
Perturb_4313_KO_Gata1_SRP059610	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.77559
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.893202
LIME1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00591469
VPS35	Pathway Commons Protein-Protein Interactions	1.0	null
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Differentially_Expressed_Genes_DEGs_of_OE-HIF1A_vs_OE-GAL4_Veh_in_Bulk_RNA-seq_Data_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
FOXM1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VPS11	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K82112239	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92558
GSE152441,GSE152442_7_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE102505_4_v_2_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE258991_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE88819_5_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052471
A-Vietnam-1203-2004(H5N1)_2day-wtC57BL-6J_None_GSE40792	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.45521
GTEX-RU72-0011-R11A-SM-2TF6J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4014
BRD-K54265757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81105
KLF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	142.854
CEBPB_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fever	CTD Gene-Disease Associations	1.0	1.10104
BRD-K76907295_VU0418947-2_VCAP_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VM-A8C9-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
promoter	GeneRIF Biological Term Annotations	1.0	null
Perturb_16417_Mut_Gli2_SRP154383	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.9478
cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.233459
GOLPH3L	Pathway Commons Protein-Protein Interactions	1.0	null
testis	HPA Tissue Protein Expression Profiles	1.0	0.78613
BRD-K00463125	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00693
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE248770_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE123638,GSE123639_3_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TELO2	Pathway Commons Protein-Protein Interactions	1.0	null
GABPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80783
E2F4	ENCODE Transcription Factor Targets	1.0	null
PMC11214527-mmc5.xlsx-POU5F1-gene_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
AD-29-IG16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.230458
metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE188570,GSE188571_5_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
PMC6747431__F5	PFOCR Pathway Figure Associations 2023	1.0	null
WF-85-JN16_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.295042
wt1_17420277_e11dot5_urogenital_ridge_lof_mouse_gpl1524_gds2747	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.358454
BRD-K87532481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36772
PMC8384902-mmc6.xlsx-DEG_ASCL1_3TF_shared-GeneSymbol_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSB-0326-SM-3LK6K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18703
GSE231799_2_v_1_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RVPU-1526-SM-47JXQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84657
GTEX-Q2AG-0011-R11A-SM-2HMKZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.42267
BRD-K36764776	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11979
Hep-G2/C3A cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.508
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-E2F4_E2F4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ETV4_ETV4	Rummagene Transcription Factor Associations 2026	1.0	null
Pinosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.063
CRCGN015_HEPG2_48H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.64555
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GSE127790_11_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XUJ4-0226-SM-4BOP8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824217
PTK2	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A75K-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN012_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.23258
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54311
Perturb_9834_KO_miR31_SRP354225	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.6289
BB-86-BE19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.430966
mononuclear phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.160062
RPS21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55447
abnormality of the thyroid gland	GWASdb SNP-Phenotype Associations	1.0	0.252944